| Year |
Citation |
Score |
| 2024 |
Göbel S, Pelz L, Silva CAT, Brühlmann B, Hill C, Altomonte J, Kamen A, Reichl U, Genzel Y. Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration. Applied Microbiology and Biotechnology. 108: 240. PMID 38413399 DOI: 10.1007/s00253-024-13078-6 |
0.399 |
|
| 2023 |
Silva CAT, Kamen AA, Henry O. Intensified Influenza Virus Production in Suspension HEK293SF Cell Cultures Operated in Fed-Batch or Perfusion with Continuous Harvest. Vaccines. 11. PMID 38140223 DOI: 10.3390/vaccines11121819 |
0.396 |
|
| 2023 |
Sène MA, Xia Y, Kamen AA. Comparative Transcriptomic Analyses of a Vero Cell Line in Suspension versus Adherent Culture Conditions. International Journal of Cell Biology. 2023: 9364689. PMID 37680537 DOI: 10.1155/2023/9364689 |
0.308 |
|
| 2023 |
Moço PD, Xu X, Silva CAT, Kamen AA. Production of adeno-associated viral vector serotype 6 by triple transfection of suspension HEK293 cells at higher cell densities. Biotechnology Journal. e2300051. PMID 37337925 DOI: 10.1002/biot.202300051 |
0.414 |
|
| 2023 |
Dash S, Farnós O, Yang Z, Sudalaiyadum Perumal A, Chaves Fulber JP, Venereo-Sánchez A, Leclerc D, Kamen AA. A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing. Protein Expression and Purification. 210: 106295. PMID 37201590 DOI: 10.1016/j.pep.2023.106295 |
0.412 |
|
| 2022 |
Sène MA, Xia Y, Kamen AA. From functional genomics of vero cells to CRISPR-based genomic deletion for improved viral production rates. Biotechnology and Bioengineering. PMID 35869699 DOI: 10.1002/bit.28190 |
0.361 |
|
| 2022 |
Tran MY, Kamen AA. Production of Lentiviral Vectors Using a HEK-293 Producer Cell Line and Advanced Perfusion Processing. Frontiers in Bioengineering and Biotechnology. 10: 887716. PMID 35774066 DOI: 10.3389/fbioe.2022.887716 |
0.337 |
|
| 2022 |
Dash S, Sharon DM, Mullick A, Kamen AA. Only a small fraction of cells produce assembled capsids during transfection-based manufacturing of adeno-associated virus vectors. Biotechnology and Bioengineering. PMID 35182435 DOI: 10.1002/bit.28068 |
0.387 |
|
| 2021 |
Fulber JPC, Farnós O, Kiesslich S, Yang Z, Dash S, Susta L, Wootton SK, Kamen AA. Process Development for Newcastle Disease Virus-Vectored Vaccines in Serum-Free Vero Cell Suspension Cultures. Vaccines. 9. PMID 34835266 DOI: 10.3390/vaccines9111335 |
0.374 |
|
| 2021 |
González-Domínguez I, Lorenzo E, Bernier A, Cervera L, Gòdia F, Kamen A. A Four-Step Purification Process for Gag VLPs: From Culture Supernatant to High-Purity Lyophilized Particles. Vaccines. 9. PMID 34696262 DOI: 10.3390/vaccines9101154 |
0.375 |
|
| 2021 |
Do Minh A, Star AT, Stupak J, Fulton KM, Haqqani AS, Gélinas JF, Li J, Twine SM, Kamen AA. Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures. Viruses. 13. PMID 33946875 DOI: 10.3390/v13050797 |
0.332 |
|
| 2021 |
Kiesslich S, Kim GN, Shen CF, Yong Kang C, Kamen AA. Bioreactor production of rVSV-based vectors in Vero cell suspension cultures. Biotechnology and Bioengineering. PMID 33837958 DOI: 10.1002/bit.27785 |
0.404 |
|
| 2020 |
Joshi PRH, Venereo-Sanchez A, Chahal PS, Kamen AA. Advancements in Molecular Systems Design and Bioprocessing of Recombinant Adeno-associated Virus Gene Delivery Vectors using the Insect-Cell Baculovirus Expression Platform. Biotechnology Journal. e2000021. PMID 33277815 DOI: 10.1002/biot.202000021 |
0.392 |
|
| 2020 |
Farnós O, Venereo-Sánchez A, Xu X, Chan C, Dash S, Chaabane H, Sauvageau J, Brahimi F, Saragovi U, Leclerc D, Kamen AA. Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation. Vaccines. 8. PMID 33158147 DOI: 10.3390/vaccines8040654 |
0.349 |
|
| 2020 |
Transfiguracion J, Tran MY, Lanthier S, Tremblay S, Coulombe N, Acchione M, Kamen AA. Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography. Molecular Therapy. Methods & Clinical Development. 18: 803-810. PMID 32953931 DOI: 10.1016/j.omtm.2020.08.005 |
0.332 |
|
| 2020 |
Kiesslich S, Kamen AA. Vero cell upstream bioprocess development for the production of viral vectors and vaccines. Biotechnology Advances. 44: 107608. PMID 32768520 DOI: 10.1016/j.biotechadv.2020.107608 |
0.334 |
|
| 2020 |
Gélinas JF, Kiesslich S, Gilbert R, Kamen AA. Titration methods for rVSV-based vaccine manufacturing. Methodsx. 7: 100806. PMID 32195130 DOI: 10.1016/j.mex.2020.100806 |
0.309 |
|
| 2020 |
Kiesslich S, Vila-Chã Losa JP, Gélinas JF, Kamen AA. Serum-free production of rVSV-ZEBOV in Vero cells: Microcarrier bioreactor versus scale-X™ hydro fixed-bed. Journal of Biotechnology. 310: 32-39. PMID 32006630 DOI: 10.1016/j.jbiotec.2020.01.015 |
0.394 |
|
| 2020 |
Do Minh A, Tran MY, Kamen AA. Lentiviral Vector Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells. Methods in Molecular Biology (Clifton, N.J.). 2086: 77-83. PMID 31707669 DOI: 10.1007/978-1-0716-0146-4_6 |
0.358 |
|
| 2020 |
Moço PD, Aharony N, Kamen A. Adeno‐Associated Viral Vectors for Homology‐Directed Generation of CAR‐T Cells Biotechnology Journal. 15: 1900286. PMID 31642193 DOI: 10.1002/Biot.201900286 |
0.396 |
|
| 2019 |
Gélinas JF, Azizi H, Kiesslich S, Lanthier S, Perdersen J, Chahal PS, Ansorge S, Kobinger G, Gilbert R, Kamen AA. Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells. Vaccine. PMID 31548015 DOI: 10.1016/j.vaccine.2019.09.044 |
0.352 |
|
| 2019 |
Venereo-Sánchez A, Fulton K, Koczka K, Twine S, Chahal P, Ansorge S, Gilbert R, Henry O, Kamen A. Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF. Vaccine. PMID 31358407 DOI: 10.1016/J.Vaccine.2019.07.057 |
0.43 |
|
| 2019 |
Shen CF, Guilbault C, Li X, Elahi SM, Ansorge S, Kamen A, Gilbert R. Development of suspension adapted Vero cell culture process technology for production of viral vaccines. Vaccine. PMID 31288997 DOI: 10.1016/J.Vaccine.2019.07.003 |
0.506 |
|
| 2019 |
Joshi PRH, Cervera L, Ahmed I, Kondratov O, Zolotukhin S, Schrag J, Chahal PS, Kamen AA. Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System. Molecular Therapy. Methods & Clinical Development. 13: 279-289. PMID 30886878 DOI: 10.1016/j.omtm.2019.02.003 |
0.359 |
|
| 2019 |
Fuenmayor J, Cervera L, Gòdia F, Kamen A. Extended gene expression for Gag VLP production achieved at bioreactor scale Journal of Chemical Technology & Biotechnology. 94: 302-308. DOI: 10.1002/Jctb.5777 |
0.365 |
|
| 2018 |
Chavez-Pena C, Kamen AA. RNA interference technology to improve the baculovirus-insect cell expression system. Biotechnology Advances. 36: 443-451. PMID 29395442 DOI: 10.1016/j.biotechadv.2018.01.008 |
0.307 |
|
| 2018 |
Gutiérrez-Granados S, Cervera L, Kamen AA, Gòdia F. Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics. Critical Reviews in Biotechnology. 38: 918-940. PMID 29295632 DOI: 10.1080/07388551.2017.1419459 |
0.407 |
|
| 2018 |
Cervera L, Kamen AA. Large-Scale Transient Transfection of Suspension Mammalian Cells for VLP Production. Methods in Molecular Biology (Clifton, N.J.). 1674: 117-127. PMID 28921433 DOI: 10.1007/978-1-4939-7312-5_10 |
0.382 |
|
| 2017 |
Robert MA, Nassoury N, Chahal PS, Venne MH, Racine T, Qiu X, Kobinger G, Kamen A, Gilbert R, Gaillet B. Gene Transfer of ZMapp Antibodies Mediated By Recombinant Adeno-Associated Virus Protects Against Ebola Infections. Human Gene Therapy. PMID 29179602 DOI: 10.1089/Hum.2017.101 |
0.342 |
|
| 2017 |
Sharon D, Kamen A. Advancements in the design and scalable production of viral gene transfer vectors. Biotechnology and Bioengineering. PMID 28941274 DOI: 10.1002/Bit.26461 |
0.413 |
|
| 2017 |
Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal P, Bourget L, Ansorge S, Gilbert R, Henry O, Kamen A. Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line. Vaccine. PMID 28648546 DOI: 10.1016/J.Vaccine.2017.06.024 |
0.49 |
|
| 2017 |
Milián E, Julien T, Biaggio R, Venereo-Sanchez A, Montes J, Manceur AP, Ansorge S, Petiot E, Rosa-Calatrava M, Kamen A. Accelerated mass production of influenza virus seed stocks in HEK-293 suspension cell cultures by reverse genetics Vaccine. 35: 3423-3430. PMID 28495315 DOI: 10.1016/J.Vaccine.2017.04.065 |
0.399 |
|
| 2017 |
Robert MA, Chahal PS, Audy A, Kamen A, Gilbert R, Gaillet B. Manufacturing of recombinant adeno-associated viruses using mammalian expression platforms. Biotechnology Journal. PMID 28177193 DOI: 10.1002/Biot.201600193 |
0.487 |
|
| 2017 |
Petiot E, Ansorge S, Rosa-Calatrava M, Kamen A. Critical phases of viral production processes monitored by capacitance. Journal of Biotechnology. 242: 19-29. PMID 27867077 DOI: 10.1016/J.Jbiotec.2016.11.010 |
0.5 |
|
| 2016 |
Venereo-Sanchez A, Gilbert R, Simoneau M, Caron A, Chahal P, Chen W, Ansorge S, Li X, Henry O, Kamen A. Hemagglutinin and neuraminidase containing virus-like particles produced in HEK-293 suspension culture: An effective influenza vaccine candidate. Vaccine. PMID 27155499 DOI: 10.1016/J.Vaccine.2016.04.089 |
0.416 |
|
| 2016 |
Shen CF, Jacob D, Zhu T, Bernier A, Shao Z, Yu X, Patel M, Lanthier S, Kamen A. Optimization and scale-up of cell culture and purification processes for production of an adenovirus-vectored tuberculosis vaccine candidate. Vaccine. PMID 27154390 DOI: 10.1016/J.Vaccine.2016.04.090 |
0.446 |
|
| 2016 |
Thompson CM, Aucoin MG, Kamen AA. Production of Virus-Like Particles for Vaccination. Methods in Molecular Biology (Clifton, N.J.). 1350: 299-315. PMID 26820864 DOI: 10.1007/978-1-4939-3043-2_14 |
0.33 |
|
| 2016 |
Thompson CM, Montes J, Aucoin MG, Kamen AA. Recombinant Protein Production in Large-Scale Agitated Bioreactors Using the Baculovirus Expression Vector System. Methods in Molecular Biology (Clifton, N.J.). 1350: 241-61. PMID 26820861 DOI: 10.1007/978-1-4939-3043-2_11 |
0.363 |
|
| 2016 |
Robert M, Kamen A, Kobinger G, Gilbert R, Gaillet B. 555. Development of a Post-Exposure Treatment for Ebola Virus Infections Based on AAV Vectors and Zmapp Antibody Cocktail Molecular Therapy. 24: S222. DOI: 10.1016/S1525-0016(16)33363-9 |
0.413 |
|
| 2016 |
Chahal P, Schulze ÉA, Bernier A, Lanthier S, Coulombe N, Kamen A, Gilbert R. 292. Towards Large-Scale Manufacturing of Adeno-Associated Virus by Transient Transfection of HEK293 Suspension Cells in a Stirred Tank Bioreactor Using Serum-Free Medium Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33101-X |
0.53 |
|
| 2015 |
Emmerling VV, Pegel A, Milian EG, Venereo-Sanchez A, Kunz M, Wegele J, Kamen AA, Kochanek S, Hoerer M. Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells. Biotechnology Journal. 11: 290-7. PMID 26284700 DOI: 10.1002/biot.201500176 |
0.413 |
|
| 2015 |
Petiot E, Cuperlovic-Culf M, Shen CF, Kamen A. Influence of HEK293 metabolism on the production of viral vectors and vaccine. Vaccine. PMID 26073013 DOI: 10.1016/J.Vaccine.2015.05.097 |
0.462 |
|
| 2015 |
Kallel H, Kamen AA. Large-scale adenovirus and poxvirus-vectored vaccine manufacturing to enable clinical trials Biotechnology Journal. 10: 741-747. PMID 25914340 DOI: 10.1002/biot.201400390 |
0.306 |
|
| 2015 |
Caron AL, Picanço-Castro V, Ansorge S, Covas DT, Kamen A, Swiech K. Production of lentiviral vectors encoding recombinant factor VIII expression in serum-free suspension cultures Brazilian Archives of Biology and Technology. 58: 923-928. DOI: 10.1590/S1516-89132015060367 |
0.475 |
|
| 2015 |
Shen CF, Jacob D, Shao Z, Bernier A, Yu X, Patel M, Zhu T, Kamen A. Optimization and scale-up of cell culture and purification processes for production of an adenovirus-based tuberculosis vaccine Bmc Proceedings. 9: 23. DOI: 10.1186/1753-6561-9-S9-P23 |
0.418 |
|
| 2014 |
Gilbert R, Guilbault C, Gagnon D, Bernier A, Bourget L, Elahi SM, Kamen A, Massie B. Establishment and validation of new complementing cells for production of E1-deleted adenovirus vectors in serum-free suspension culture. Journal of Virological Methods. 208: 177-88. PMID 25159033 DOI: 10.1016/J.Jviromet.2014.08.013 |
0.503 |
|
| 2014 |
Trabelsi K, Kamen A, Kallel H. Development of a vectored vaccine against Hepatitis E virus Vaccine. 32: 2808-2811. PMID 24583005 DOI: 10.1016/J.Vaccine.2014.02.041 |
0.441 |
|
| 2014 |
Chahal PS, Schulze E, Tran R, Montes J, Kamen AA. Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery. Journal of Virological Methods. 196: 163-73. PMID 24239634 DOI: 10.1016/j.jviromet.2013.10.038 |
0.4 |
|
| 2014 |
Merten O, Schweizer M, Chahal P, Kamen A. Manufacturing of viral vectors: part II. Downstream processing and safety aspects Pharmaceutical Bioprocessing. 2: 237-251. DOI: 10.4155/Pbp.14.15 |
0.418 |
|
| 2013 |
Emma P, Kamen A. Real-time monitoring of influenza virus production kinetics in HEK293 cell cultures Biotechnology Progress. 29: 275-284. PMID 22848016 DOI: 10.1002/Btpr.1601 |
0.468 |
|
| 2012 |
Shao W, Paul A, Abbasi S, Chahal PS, Mena JA, Montes J, Kamen A, Prakash S. A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis. International Journal of Nanomedicine. 7: 1575-86. PMID 22619514 DOI: 10.2147/Ijn.S26891 |
0.399 |
|
| 2012 |
Garnier A, Voyer R, Tom R, Perret S, Jardin B, Kamen A. Dissolved carbon dioxide accumulation in a large scale and high density production of TGFβ receptor with baculovirus infected Sf-9 cells. Cytotechnology. 22: 53-63. PMID 22358915 DOI: 10.1007/Bf00353924 |
0.426 |
|
| 2012 |
Male KB, Leung AC, Montes J, Kamen A, Luong JH. Probing inhibitory effects of nanocrystalline cellulose: inhibition versus surface charge. Nanoscale. 4: 1373-9. PMID 22252333 DOI: 10.1039/C2Nr11886F |
0.364 |
|
| 2012 |
Shen CF, Kamen A. Hyperosmotic pressure on HEK 293 cells during the growth phase, but not the production phase, improves adenovirus production. Journal of Biotechnology. 157: 228-36. PMID 22154564 DOI: 10.1016/J.Jbiotec.2011.11.016 |
0.473 |
|
| 2012 |
Shen CF, Lanthier S, Jacob D, Montes J, Beath A, Beresford A, Kamen A. Process optimization and scale-up for production of rabies vaccine live adenovirus vector (AdRG1.3). Vaccine. 30: 300-6. PMID 22079076 DOI: 10.1016/J.Vaccine.2011.10.095 |
0.365 |
|
| 2012 |
Nadeau I, Garnier A, Côté J, Massie B, Chavarie C, Kamen A. Improvement of recombinant protein production with the human adenovirus/293S expression system using fed-batch strategies. Biotechnology and Bioengineering. 51: 613-23. PMID 18629828 DOI: 10.1002/(Sici)1097-0290(19960920)51:6<613::Aid-Bit1>3.0.Co;2-K |
0.495 |
|
| 2011 |
Swiech K, Kamen A, Ansorge S, Durocher Y, Picanço-Castro V, Russo-Carbolante EM, Neto MS, Covas DT. Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII. Bmc Biotechnology. 11: 114. PMID 22115125 DOI: 10.1186/1472-6750-11-114 |
0.446 |
|
| 2011 |
Petiot E, Jacob D, Lanthier S, Lohr V, Ansorge S, Kamen AA. Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture. Bmc Biotechnology. 11: 84. PMID 21884612 DOI: 10.1186/1472-6750-11-84 |
0.36 |
|
| 2011 |
Dormond E, Kamen AA. Manufacturing of adenovirus vectors: production and purification of helper dependent adenovirus Methods in Molecular Biology (Clifton, N.J.). 737: 139-156. PMID 21590396 DOI: 10.1007/978-1-61779-095-9_6 |
0.341 |
|
| 2011 |
Segura MM, Kamen AA, Garnier A. Overview of current scalable methods for purification of viral vectors. Methods in Molecular Biology (Clifton, N.J.). 737: 89-116. PMID 21590394 DOI: 10.1007/978-1-61779-095-9_4 |
0.332 |
|
| 2011 |
Henry O, Jolicoeur M, Kamen A. Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis. Bioprocess and Biosystems Engineering. 34: 263-73. PMID 20848294 DOI: 10.1007/S00449-010-0468-9 |
0.39 |
|
| 2011 |
Cass B, Pham PL, Kamen A, Durocher Y. Reprint of: Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme Protein Expression and Purification. DOI: 10.1016/J.Pep.2011.08.012 |
0.402 |
|
| 2011 |
Ansorge S, Lanthier S, Transfiguracion J, Henry O, Kamen A. Monitoring lentiviral vector production kinetics using online permittivity measurements Biochemical Engineering Journal. 54: 16-25. DOI: 10.1016/J.Bej.2011.01.002 |
0.453 |
|
| 2010 |
Mahmoud KA, Mena JA, Male KB, Hrapovic S, Kamen A, Luong JH. Effect of surface charge on the cellular uptake and cytotoxicity of fluorescent labeled cellulose nanocrystals. Acs Applied Materials & Interfaces. 2: 2924-32. PMID 20919683 DOI: 10.1021/Am1006222 |
0.329 |
|
| 2010 |
Aucoin MG, Mena JA, Kamen AA. Bioprocessing of baculovirus vectors: a review. Current Gene Therapy. 10: 174-86. PMID 20380645 DOI: 10.2174/156652310791321288 |
0.328 |
|
| 2010 |
Le Ru A, Jacob D, Transfiguracion J, Ansorge S, Henry O, Kamen AA. Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing. Vaccine. 28: 3661-71. PMID 20347632 DOI: 10.1016/J.Vaccine.2010.03.029 |
0.358 |
|
| 2010 |
Segura MM, Garnier A, Durocher Y, Ansorge S, Kamen A. New protocol for lentiviral vector mass production. Methods in Molecular Biology (Clifton, N.J.). 614: 39-52. PMID 20225034 DOI: 10.1007/978-1-60761-533-0_2 |
0.465 |
|
| 2010 |
Dormond E, Chahal P, Bernier A, Tran R, Perrier M, Kamen A. An efficient process for the purification of helper-dependent adenoviral vector and removal of helper virus by iodixanol ultracentrifugation. Journal of Virological Methods. 165: 83-9. PMID 20116403 DOI: 10.1016/J.Jviromet.2010.01.008 |
0.382 |
|
| 2010 |
Mena JA, Aucoin MG, Montes J, Chahal PS, Kamen AA. Improving adeno-associated vector yield in high density insect cell cultures. The Journal of Gene Medicine. 12: 157-67. PMID 20101623 DOI: 10.1002/jgm.1420 |
0.398 |
|
| 2010 |
Shen CF, Voyer R, Tom R, Kamen A. Reassessing culture media and critical metabolites that affect adenovirus production. Biotechnology Progress. 26: 200-7. PMID 19728394 DOI: 10.1002/Btpr.286 |
0.49 |
|
| 2010 |
Ansorge S, Henry O, Kamen A. Recent progress in lentiviral vector mass production Biochemical Engineering Journal. 48: 362-377. DOI: 10.1016/J.Bej.2009.10.017 |
0.457 |
|
| 2009 |
Meghrous J, Mahmoud W, Jacob D, Chubet R, Cox M, Kamen AA. Development of a simple and high-yielding fed-batch process for the production of influenza vaccines. Vaccine. 28: 309-16. PMID 19879996 DOI: 10.1016/j.vaccine.2009.10.048 |
0.356 |
|
| 2009 |
Ansorge S, Lanthier S, Transfiguracion J, Durocher Y, Henry O, Kamen A. Development of a scalable process for high-yield lentiviral vector production by transient transfection of HEK293 suspension cultures. The Journal of Gene Medicine. 11: 868-76. PMID 19618482 DOI: 10.1002/Jgm.1370 |
0.512 |
|
| 2009 |
Dormond E, Perrier M, Kamen A. Identification of critical infection parameters to control helper-dependent adenoviral vector production Journal of Biotechnology. 142: 142-150. PMID 19501266 DOI: 10.1016/J.Jbiotec.2009.03.021 |
0.431 |
|
| 2009 |
Ghani K, Wang X, Campos-Lima POd, Olszewska M, Kamen A, Rivière I, Caruso M. Efficient Human Hematopoietic Cell Transduction Using RD114- and GALV-Pseudotyped Retroviral Vectors Produced in Suspension and Serum-Free Media Human Gene Therapy. 20: 966-974. PMID 19453219 DOI: 10.1089/Hum.2009.001 |
0.506 |
|
| 2009 |
Dormond E, Perrier M, Kamen A. From the first to the third generation adenoviral vector: What parameters are governing the production yield? Biotechnology Advances. 27: 133-144. PMID 19013226 DOI: 10.1016/J.Biotechadv.2008.10.003 |
0.484 |
|
| 2009 |
Dormond E, Meneses-Acosta A, Jacob D, Durocher Y, Gilbert R, Perrier M, Kamen A. An efficient and scalable process for helper-dependent adenoviral vector production using polyethylenimine-adenofection Biotechnology and Bioengineering. 102: 800-810. PMID 18821637 DOI: 10.1002/Bit.22113 |
0.516 |
|
| 2008 |
Transfiguracion J, Bernier A, Voyer R, Coelho H, Coffey M, Kamen A. Rapid and reliable quantification of reovirus type 3 by high performance liquid chromatography during manufacturing of Reolysin Journal of Pharmaceutical and Biomedical Analysis. 48: 598-605. PMID 18632239 DOI: 10.1016/J.Jpba.2008.05.038 |
0.379 |
|
| 2008 |
Segura MM, Kamen A, Garnier A. Purification of retrovirus particles using heparin affinity chromatography. Methods in Molecular Biology (Clifton, N.J.). 434: 1-11. PMID 18470635 DOI: 10.1007/978-1-60327-248-3_1 |
0.417 |
|
| 2008 |
Meneses-Acosta A, Dormond E, Jacob D, Tom R, Bernier A, Perret S, St-Laurent G, Durocher Y, Gilbert R, Kamen A. Development of a suspension serum-free helper-dependent adenovirus production system and assessment of co-infection conditions. Journal of Virological Methods. 148: 106-14. PMID 18079009 DOI: 10.1016/J.Jviromet.2007.10.017 |
0.465 |
|
| 2008 |
Segura MM, Garnier A, Di Falco MR, Whissell G, Meneses-Acosta A, Arcand N, Kamen A. Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations. Journal of Virology. 82: 1107-17. PMID 18032515 DOI: 10.1128/Jvi.01909-07 |
0.354 |
|
| 2008 |
Aucoin MG, Perrier M, Kamen AA. Critical assessment of current adeno-associated viral vector production and quantification methods. Biotechnology Advances. 26: 73-88. PMID 17964108 DOI: 10.1016/J.Biotechadv.2007.09.001 |
0.322 |
|
| 2007 |
Shen CF, Kiyota T, Jardin B, Konishi Y, Kamen A. Characterization of yeastolate fractions that promote insect cell growth and recombinant protein production. Cytotechnology. 54: 25-34. PMID 19003015 DOI: 10.1007/S10616-007-9062-7 |
0.343 |
|
| 2007 |
Aucoin MG, Jacob D, Chahal PS, Meghrous J, Bernier A, Kamen AA. Virus-like particle and viral vector production using the baculovirus expression vector system/insect cell system: adeno-associated virus-based products. Methods in Molecular Biology (Clifton, N.J.). 388: 281-96. PMID 17951776 DOI: 10.1007/978-1-59745-457-5_14 |
0.346 |
|
| 2007 |
Elias CB, Jardin B, Kamen A. Recombinant protein production in large-scale agitated bioreactors using the baculovirus expression vector system Methods in Molecular Biology. 388: 225-245. PMID 17951773 DOI: 10.1385/1-59745-457-5:225 |
0.408 |
|
| 2007 |
Ghani K, Cottin S, Kamen A, Caruso M. Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media Gene Therapy. 14: 1705-1711. PMID 17928873 DOI: 10.1038/Sj.Gt.3303039 |
0.509 |
|
| 2007 |
Gilbert PA, Kamen A, Bernier A, Garnier A. A simple macroscopic model for the diffusion and adsorption kinetics of r-adenovirus. Biotechnology and Bioengineering. 98: 239-51. PMID 17597100 DOI: 10.1002/Bit.21340 |
0.345 |
|
| 2007 |
Durocher Y, Pham PL, St-Laurent G, Jacob D, Cass B, Chahal P, Lau CJ, Nalbantoglu J, Kamen A. Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells. Journal of Virological Methods. 144: 32-40. PMID 17467815 DOI: 10.1016/J.Jviromet.2007.03.014 |
0.552 |
|
| 2007 |
Segura MM, Garnier A, Durocher Y, Coelho H, Kamen A. Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification. Biotechnology and Bioengineering. 98: 789-99. PMID 17461423 DOI: 10.1002/Bit.21467 |
0.486 |
|
| 2007 |
Transfiguracion J, Jorio H, Meghrous J, Jacob D, Kamen A. High yield purification of functional baculovirus vectors by size exclusion chromatography. Journal of Virological Methods. 142: 21-28. PMID 17306891 DOI: 10.1016/J.Jviromet.2007.01.002 |
0.474 |
|
| 2007 |
Carpentier E, Paris S, Kamen AA, Durocher Y. Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells. Journal of Biotechnology. 128: 268-80. PMID 17118475 DOI: 10.1016/J.Jbiotec.2006.10.014 |
0.3 |
|
| 2007 |
Chahal PS, Aucoin MG, Kamen A. Primary recovery and chromatographic purification of adeno-associated virus type 2 produced by baculovirus/insect cell system. Journal of Virological Methods. 139: 61-70. PMID 17055590 DOI: 10.1016/J.Jviromet.2006.09.011 |
0.414 |
|
| 2007 |
Segura MM, Kamen A, Lavoie MC, Garnier A. Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 846: 124-31. PMID 16971193 DOI: 10.1016/J.Jchromb.2006.08.032 |
0.375 |
|
| 2007 |
Henry O, Ansorge S, Aucoin M, Voyer R, Kamen A. On-Line Monitoring Of Cell Size Distribution In Mammalian Cell Culture Processes Ifac Proceedings Volumes. 40: 277-282. DOI: 10.3182/20070604-3-Mx-2914.00048 |
0.392 |
|
| 2007 |
Henry O, Kamen A, Perrier M. Monitoring the physiological state of mammalian cell perfusion processes by on-line estimation of intracellular fluxes Journal of Process Control. 17: 241-251. DOI: 10.3182/20060402-4-Br-2902.00047 |
0.367 |
|
| 2006 |
Pham PL, Kamen A, Durocher Y. Large-scale transfection of mammalian cells for the fast production of recombinant protein. Molecular Biotechnology. 34: 225-37. PMID 17172668 DOI: 10.1385/Mb:34:2:225 |
0.388 |
|
| 2006 |
Aucoin MG, Perrier M, Kamen AA. Production of adeno-associated viral vectors in insect cells using triple infection: optimization of baculovirus concentration ratios. Biotechnology and Bioengineering. 95: 1081-92. PMID 16952153 DOI: 10.1002/Bit.21069 |
0.399 |
|
| 2006 |
Ghani K, Garnier A, Coelho H, Transfiguracion J, Trudel P, Kamen A. Retroviral vector production using suspension-adapted 293GPG cells in a 3L acoustic filter-based perfusion bioreactor. Biotechnology and Bioengineering. 95: 653-60. PMID 16947907 DOI: 10.1002/Bit.20947 |
0.529 |
|
| 2006 |
Jorio H, Tran R, Kamen A. Stability of serum-free and purified baculovirus stocks under various storage conditions. Biotechnology Progress. 22: 319-25. PMID 16454526 DOI: 10.1021/Bp050218V |
0.35 |
|
| 2006 |
Segura MM, Kamen A, Garnier A. Downstream processing of oncoretroviral and lentiviral gene therapy vectors. Biotechnology Advances. 24: 321-37. PMID 16448798 DOI: 10.1016/J.Biotechadv.2005.12.001 |
0.403 |
|
| 2006 |
Jorio H, Tran R, Meghrous J, Bourget L, Kamen A. Analysis of baculovirus aggregates using flow cytometry. Journal of Virological Methods. 134: 8-14. PMID 16364459 DOI: 10.1016/J.Jviromet.2005.11.009 |
0.3 |
|
| 2006 |
Segura MM, Garnier A, Kamen A. Purification and characterization of retrovirus vector particles by rate zonal ultracentrifugation. Journal of Virological Methods. 133: 82-91. PMID 16325928 DOI: 10.1016/J.Jviromet.2005.10.030 |
0.381 |
|
| 2006 |
Deschênes JS, Desbiens A, Perrier M, Kamen A. Use of cell bleed in a high cell density perfusion culture and multivariable control of biomass and metabolite concentrations Asia-Pacific Journal of Chemical Engineering. 1: 82-91. DOI: 10.1002/Apj.10 |
0.394 |
|
| 2005 |
Altaras NE, Aunins JG, Evans RK, Kamen A, Konz JO, Wolf JJ. Production and formulation of adenovirus vectors. Advances in Biochemical Engineering/Biotechnology. 99: 193-260. PMID 16568893 DOI: 10.1007/10_008 |
0.443 |
|
| 2005 |
Henry O, Perrier M, Kamen A. Metabolic flux analysis of HEK-293 cells in perfusion cultures for the production of adenoviral vectors. Metabolic Engineering. 7: 467-76. PMID 16198135 DOI: 10.1016/J.Ymben.2005.08.002 |
0.467 |
|
| 2005 |
Meghrous J, Aucoin MG, Jacob D, Chahal PS, Arcand N, Kamen AA. Production of recombinant adeno-associated viral vectors using a baculovirus/insect cell suspension culture system: from shake flasks to a 20-L bioreactor. Biotechnology Progress. 21: 154-60. PMID 15903253 DOI: 10.1021/bp049802e |
0.371 |
|
| 2005 |
Benslimane C, Elias CB, Hawari J, Kamen A. Insights into the central metabolism of Spodoptera frugiperda (Sf-9) and Trichoplusia ni BTI-Tn-5B1-4 (Tn-5) insect cells by radiolabeling studies Biotechnology Progress. 21: 78-86. PMID 15903243 DOI: 10.1021/Bp049800U |
0.37 |
|
| 2005 |
Segura MM, Kamen A, Trudel P, Garnier A. A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography. Biotechnology and Bioengineering. 90: 391-404. PMID 15812800 DOI: 10.1002/Bit.20301 |
0.399 |
|
| 2005 |
Pham PL, Perret S, Cass B, Carpentier E, St-Laurent G, Bisson L, Kamen A, Durocher Y. Transient gene expression in HEK293 cells: peptone addition posttransfection improves recombinant protein synthesis. Biotechnology and Bioengineering. 90: 332-44. PMID 15803471 DOI: 10.1002/Bit.20428 |
0.448 |
|
| 2005 |
Cass B, Pham PL, Kamen A, Durocher Y. Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme. Protein Expression and Purification. 40: 77-85. PMID 15721774 DOI: 10.1016/J.Pep.2004.10.023 |
0.402 |
|
| 2005 |
Durocher Y, Pham PL, St-Laurent G, Jacob D, Cass B, Nalbantoglu J, Kamen A. 518. Production of Recombinant Type 2 Adeno-Associated Virus in Bioreactors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.058 |
0.512 |
|
| 2004 |
Transfiguracion J, Coelho H, Kamen A. High-performance liquid chromatographic total particles quantification of retroviral vectors pseudotyped with vesicular stomatitis virus-G glycoprotein Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 813: 167-173. PMID 15556530 DOI: 10.1016/J.Jchromb.2004.09.034 |
0.407 |
|
| 2004 |
Shen CF, Hawari J, Kamen A. Micro-quantitation of lipids in serum-free cell culture media: a critical aspect is the minimization of interference from medium components and chemical reagents. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 810: 119-27. PMID 15358315 DOI: 10.1016/J.Jchromb.2004.07.020 |
0.338 |
|
| 2004 |
Henry O, Dormond E, Perrier M, Kamen A. Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures. Biotechnology and Bioengineering. 86: 765-74. PMID 15162452 DOI: 10.1002/Bit.20074 |
0.497 |
|
| 2004 |
Shirgaonkar IZ, Lanthier S, Kamen A. Acoustic cell filter: A proven cell retention technology for perfusion of animal cell cultures Biotechnology Advances. 22: 433-444. PMID 15135491 DOI: 10.1016/J.Biotechadv.2004.03.003 |
0.369 |
|
| 2004 |
Kamen A, Henry O. Development and optimization of an adenovirus production process. The Journal of Gene Medicine. 6: S184-92. PMID 14978761 DOI: 10.1002/Jgm.503 |
0.505 |
|
| 2004 |
Henry O, Perrier M, Kamen A. On-Line Monitoring of Adenovirus Production in Perfusion Cultures Ifac Proceedings Volumes. 37: 381-386. DOI: 10.1016/S1474-6670(17)32611-3 |
0.44 |
|
| 2003 |
Nadeau I, Kamen A. Production of adenovirus vector for gene therapy. Biotechnology Advances. 20: 475-89. PMID 14550017 DOI: 10.1016/S0734-9750(02)00030-7 |
0.449 |
|
| 2003 |
Pham PL, Perret S, Doan HC, Cass B, St-Laurent G, Kamen A, Durocher Y. Large-scale transient transfection of serum-free suspension-growing HEK293 EBNA1 cells: peptone additives improve cell growth and transfection efficiency. Biotechnology and Bioengineering. 84: 332-42. PMID 12968287 DOI: 10.1002/Bit.10774 |
0.447 |
|
| 2003 |
Transfiguracion J, Jaalouk DE, Ghani K, Galipeau J, Kamen A. Size-Exclusion Chromatography Purification of High-Titer Vesicular Stomatitis Virus G Glycoprotein-Pseudotyped Retrovectors for Cell and Gene Therapy Applications Human Gene Therapy. 14: 1139-1153. PMID 12908966 DOI: 10.1089/104303403322167984 |
0.444 |
|
| 2003 |
Elias CB, Carpentier E, Durocher Y, Bisson L, Wagner R, Kamen A. Improving glucose and glutamine metabolism of human HEK 293 and Trichoplusia ni insect cells engineered to express a cytosolic pyruvate carboxylase enzyme. Biotechnology Progress. 19: 90-7. PMID 12573011 DOI: 10.1021/Bp025572X |
0.401 |
|
| 2002 |
Shen CF, Meghrous J, Kamen A. Quantitation of baculovirus particles by flow cytometry. Journal of Virological Methods. 105: 321-30. PMID 12270664 DOI: 10.1016/S0166-0934(02)00128-3 |
0.405 |
|
| 2002 |
Durocher Y, Perret S, Kamen A. High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Research. 30: E9. PMID 11788735 DOI: 10.1093/Nar/30.2.E9 |
0.458 |
|
| 2002 |
Nadeau I, Gilbert PA, Jacob D, Perrier M, Kamen A. Low-protein medium affects the 293SF central metabolism during growth and infection with adenovirus. Biotechnology and Bioengineering. 77: 91-104. PMID 11745177 DOI: 10.1002/Bit.10128 |
0.418 |
|
| 2001 |
Gilbert R, Nalbantoglu J, Howell JM, Davies L, Fletcher S, Amalfitano A, Petrof BJ, Kamen A, Massie B, Karpati G. Dystrophin expression in muscle following gene transfer with a fully deleted ("gutted") adenovirus is markedly improved by trans-acting adenoviral gene products. Human Gene Therapy. 12: 1741-55. PMID 11560768 DOI: 10.1089/104303401750476249 |
0.361 |
|
| 2001 |
Klyushnichenko V, Bernier A, Kamen A, Harmsen E. Improved high-performance liquid chromatographic method in the analysis of adenovirus particles Journal of Chromatography B: Biomedical Sciences and Applications. 755: 27-36. PMID 11393714 DOI: 10.1016/S0378-4347(00)00597-1 |
0.327 |
|
| 2001 |
Luong JHT, Habibi-Rezaei M, Meghrous J, Xiao C, Male KB, Kamen A. Monitoring motility, spreading, and mortality of adherent insect cells using an impedance sensor. Analytical Chemistry. 73: 1844-1848. PMID 11338600 DOI: 10.1021/Ac0011585 |
0.37 |
|
| 2001 |
Garnier A, Gilbert P, Kamen A. Modeling of the Diffusion/ Adsorption Process of 293S Cells Infected by Recombinant Adenoviruses Ifac Proceedings Volumes. 34: 367-372. DOI: 10.1016/S1474-6670(17)34247-7 |
0.326 |
|
| 2001 |
Nadeau I, Jacob D, Henry O, Perrier M, Kamen A. Enhanced Adenovirus Production by 293 Cells Using a Low-Protein Medium: A Metabolic Flux Analysis Ifac Proceedings Volumes. 34: 361-366. DOI: 10.1016/S1474-6670(17)34246-5 |
0.422 |
|
| 2000 |
Nadeau I, Sabatié J, Koehl M, Perrier M, Kamen A. Human 293 cell metabolism in low glutamine-supplied culture: interpretation of metabolic changes through metabolic flux analysis. Metabolic Engineering. 2: 277-92. PMID 11120640 DOI: 10.1006/Mben.2000.0152 |
0.377 |
|
| 2000 |
Nadeau I, Jacob D, Perrier M, Kamen A. 293SF metabolic flux analysis during cell growth and infection with an adenoviral vector. Biotechnology Progress. 16: 872-84. PMID 11027184 DOI: 10.1021/Bp000098L |
0.424 |
|
| 2000 |
Durocher Y, Perret S, Thibaudeau E, Gaumond MH, Kamen A, Stocco R, Abramovitz M. A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture. Analytical Biochemistry. 284: 316-26. PMID 10964415 DOI: 10.1006/Abio.2000.4698 |
0.336 |
|
| 2000 |
Meghrous J, Kamen A, Palli SR, Sohi SS, Caputo GF, Bedard SC. Production of Choristoneura fumiferana Nucleopolyhedrovirus in C. fumiferana (CF-2C1 Cells) in a 3 Litre Bioreactor Using Serum-free Medium Biocontrol Science and Technology. 10: 301-313. DOI: 10.1080/09583150050044574 |
0.432 |
|
| 2000 |
Gilbert PA, Garnier A, Jacob D, Kamen A. On-line measurement of green fluorescent protein (GFP) fluorescence for the monitoring of recombinant adenovirus production Biotechnology Letters. 22: 561-567. DOI: 10.1023/A:1005672410905 |
0.37 |
|
| 1999 |
Siegwart P, Côté J, Male K, Luong JH, Perrier M, Kamen A. Adaptive control at low glucose concentration of HEK-293 cell serum-free cultures. Biotechnology Progress. 15: 608-16. PMID 10441351 DOI: 10.1021/Bp990077V |
0.369 |
|
| 1998 |
Côté J, Garnier A, Massie B, Kamen A. Serum-free production of recombinant proteins and adenoviral vectors by 293SF-3F6 cells Biotechnology and Bioengineering. 59: 567-575. PMID 10099373 DOI: 10.1002/(Sici)1097-0290(19980905)59:5<567::Aid-Bit6>3.0.Co;2-8 |
0.473 |
|
| 1997 |
Côté J, Bourget L, Garnier A, Kamen A. Study of adenovirus production in serum-free 293SF suspension culture by GFP-expression monitoring Biotechnology Progress. 13: 709-714. PMID 9413130 DOI: 10.1021/Bp970110I |
0.453 |
|
| 1997 |
Bédard C, Perret S, Kamen AA. Fed-batch culture of Sf-9 cells supports 3 x 107 cells per ml and improves baculovirus-expressed recombinant protein yields Biotechnology Letters. 19: 629-632. DOI: 10.1023/A:1018378529299 |
0.306 |
|
| 1994 |
Garnier A, Côté J, Nadeau I, Kamen A, Massie B. Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells Cytotechnology. 15: 145-155. PMID 7765926 DOI: 10.1007/Bf00762389 |
0.509 |
|
| 1994 |
Bédard C, Kamen A, Tom R, Massie B. Maximization of recombinant protein yield in the insect cell/baculovirus system by one-time addition of nutrients to high-density batch cultures. Cytotechnology. 15: 129-38. PMID 7765925 DOI: 10.1007/Bf00762387 |
0.424 |
|
| 1994 |
Bédard C, Jolicoeur M, Jardin B, Tom R, Perret S, Kamen A. Insect cell density in bioreactor cultures can be estimated from on-line measurements of optical density Biotechnology Techniques. 8: 605-610. DOI: 10.1007/Bf00241682 |
0.405 |
|
| 1994 |
Caron AW, Tom RL, Kamen AA, Massie B. Baculovirus expression system scaleup by perfusion of high-density Sf-9 cell cultures Biotechnology and Bioengineering. 43: 881-891. DOI: 10.1002/Bit.260430907 |
0.388 |
|
| 1993 |
Bédard C, Tom R, Kamen A. Growth, nutrient consumption, and end-product accumulation in Sf-9 and BTI-EAA insect cell cultures: insights into growth limitation and metabolism. Biotechnology Progress. 9: 615-24. PMID 7764350 DOI: 10.1021/Bp00024A008 |
0.42 |
|
| 1993 |
Côte J, Kamen AA, André G. Protein-free culture medium improvement: testing additives and their interactive effects in 96-well plates Applied Microbiology and Biotechnology. 39: 577-584. DOI: 10.1007/BF00205055 |
0.326 |
|
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