Year |
Citation |
Score |
2020 |
Yirsaw AW, Gillespie A, Briton E, Doerle A, Johnson L, Marston S, Telfer J, Baldwin CL. Goat γδ T cell subpopulations defined by WC1 expression, responses to pathogens and cytokine production. Developmental and Comparative Immunology. 103984. PMID 33352199 DOI: 10.1016/j.dci.2020.103984 |
0.361 |
|
2019 |
Uger R, Johnson L. Blockade of the CD47-SIRPα axis: a promising approach for cancer immunotherapy. Expert Opinion On Biological Therapy. 20: 5-8. PMID 31663384 DOI: 10.1080/14712598.2020.1685976 |
0.402 |
|
2019 |
Kruglov O, Johnson LD, Uger RA, Wong M, Wu X, Hwang ST, Akilov OE. Anti-CD7 immunotherapy is mediated by cytotoxic CD107a+IFN-γ– NK cells and can be potentiated by interferon-α in cutaneous lymphoma European Journal of Cancer. 119: S33. DOI: 10.1016/s0959-8049(19)30600-8 |
0.324 |
|
2018 |
Querfeld C, Thompson J, Taylor MH, Pillai R, Johnson LD, Catalano T, Petrova PS, Thompson T, Uger RA, Shou Y, Akilov OE. Intralesional Administration of the CD47 Antagonist TTI-621 (SIRPαFc) Induces Responses in Both Injected and Non-Injected Lesions in Patients with Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Interim Results of a Multicenter Phase I Trial Blood. 132: 1653-1653. DOI: 10.1182/Blood-2018-99-116915 |
0.351 |
|
2018 |
Lin GHY, Viller NN, Chabonneau M, Brinen L, Mutukura T, Dodge K, Helke S, Chai V, House V, Lee V, Chen H, O'Connor A, Jin D, Figueredo R, Vareki SM, ... ... Johnson LD, et al. Abstract 2709: TTI-622 (SIRPα-IgG4 Fc), a CD47-blocking innate immune checkpoint inhibitor, suppresses tumor growth and demonstrates enhanced efficacy in combination with antitumor antibodies in both hematologic and solid tumor models Cancer Research. 78: 2709-2709. DOI: 10.1158/1538-7445.Am2018-2709 |
0.383 |
|
2018 |
Querfeld C, Thompson JA, Taylor M, Pillai R, Johnson LD, Catalano T, Petrova PS, Uger BA, Irwin M, Thompson T, Sievers EL, Akilov O. Intralesional Injection of the CD47-blocking immune checkpoint inhibitor TTI-621 (SIRPaFc) induces antitumor activity in patients with relapsed/refractory mycosis fungoides and Sézary syndrome: Interim results of a multicenter Phase 1 trial European Journal of Cancer. 101: S34. DOI: 10.1016/J.Ejca.2018.07.297 |
0.372 |
|
2017 |
Lin GHY, Chai V, Lee V, Dodge K, Truong T, Wong M, Johnson LD, Linderoth E, Pang X, Winston J, Petrova PS, Uger RA, Viller NN. TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets. Plos One. 12: e0187262. PMID 29084248 DOI: 10.1371/Journal.Pone.0187262 |
0.403 |
|
2017 |
Johnson L, Pillai RK, King RL, Ansell SM, Chen RW, Flinn I, Maris MB, Irwin M, Sievers EL, Petrova PS, Uger RA. Effects of TTI-621 (SIRPαFc) on CD47 and serum cytokines associated with phagocytosis in subjects with relapsed, refractory hematologic malignancies: Pharmacodynamic findings from a first-in-human clinical trial. Journal of Clinical Oncology. 35: 112-112. DOI: 10.1200/Jco.2017.35.7_Suppl.112 |
0.502 |
|
2017 |
Thompson JA, Akilov O, Querfeld C, Taylor MH, Johnson L, Catalano T, Petrova PS, Uger RA, Irwin M, Sievers EL. A phase 1 dose-escalation trial of intratumoral TTI-621, a novel immune checkpoint inhibitor targeting CD47, in subjects with relapsed or refractory percutaneously-accessible solid tumors and mycosis fungoides. Journal of Clinical Oncology. 35: TPS3101-TPS3101. DOI: 10.1200/Jco.2017.35.15_Suppl.Tps3101 |
0.444 |
|
2017 |
Querfeld C, Thompson J, Taylor M, Pillai R, Johnson LD, Catalano T, Petrova PS, Uger RA, Irwin M, Sievers EL, Akilov OE. A Single Direct Intratumoral Injection of TTI-621 (SIRPαFc) Induces Antitumor Activity in Patients with Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Preliminary Findings Employing an Immune Checkpoint Inhibitor Blocking the CD47 Do Not Eat Signal Blood. 130: 4076-4076. DOI: 10.1182/Blood.V130.Suppl_1.4076.4076 |
0.416 |
|
2017 |
Linderoth E, Helke S, Lee V, Mutukura T, Wong M, Lin GH, Johnson LD, Pang X, Winston J, Petrova PS, Uger RA, Viller NN. Abstract 2653: The anti-myeloma activity of TTI-621 (SIRPαFc), a CD47-blocking immunotherapeutic, is enhanced when combined with a proteasome inhibitor Cancer Research. 77: 2653-2653. DOI: 10.1158/1538-7445.Am2017-2653 |
0.468 |
|
2017 |
Lin GH, Charbonneau M, Chai V, O'Connor AM, Bossen B, Chen H, Wong M, Viller NN, Linderoth E, Johnson LD, Pang X, Winston J, Petrova PS, Uger RA. Abstract 2646: Intratumoral delivery of TTI-621 (SIRPαFc), a CD47-blocking immunotherapeutic, inhibits tumor growth and prolongs animal survival in a subcutaneous B cell lymphoma model Cancer Research. 77: 2646-2646. DOI: 10.1158/1538-7445.Am2017-2646 |
0.408 |
|
2016 |
Petrova PS, Viller NN, Wong M, Pang X, Lin GH, Dodge K, Chai V, Chen H, Lee V, House V, Vigo NT, Jin D, Mutukura T, Charbonneau M, Truong T, ... ... Johnson LD, et al. TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Anti-Tumor Activity and Minimal Erythrocyte Binding. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27856600 DOI: 10.1158/1078-0432.Ccr-16-1700 |
0.478 |
|
2016 |
Ansell S, Chen RW, Flinn IW, Maris MB, O'Connor OA, Johnson LD, Irwin M, Petrova PS, Uger RA, Sievers EL. A Phase 1 Study of TTI-621, a Novel Immune Checkpoint Inhibitor Targeting CD47, in Patients with Relapsed or Refractory Hematologic Malignancies Blood. 128: 1812-1812. DOI: 10.1182/Blood.V128.22.1812.1812 |
0.394 |
|
2016 |
Viller NN, Truong T, Linderoth E, Johnson LD, Viau S, Lin GHY, Wong M, Pang X, Petrova PS, Uger RA. Abstract B028: Blockade of the CD47 “Do not eat” signal by TTI-621 (SIRPαFc) leads to enhanced antitumor CD8+ T cell responses in vitro Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B028 |
0.555 |
|
2013 |
Johnson LD, Beckham WA, Russell GH, Lum JJ, Vlachaki MT. Abstract B51: Synergistic effects of αCTLA-4 and radiotherapy in the treatment of prostate cancer. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-B51 |
0.378 |
|
2012 |
Johnson LD, Jameson SC. TGF-β sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15. Plos One. 7: e42268. PMID 22879925 DOI: 10.1371/Journal.Pone.0042268 |
0.61 |
|
2010 |
Johnson LD, Jameson SC. Self-specific CD8+ T cells maintain a semi-naive state following lymphopenia-induced proliferation. Journal of Immunology (Baltimore, Md. : 1950). 184: 5604-11. PMID 20393139 DOI: 10.4049/Jimmunol.1000109 |
0.646 |
|
2009 |
Johnson LD, Jameson SC. Immunology. A chronic need for IL-21. Science (New York, N.Y.). 324: 1525-6. PMID 19541985 DOI: 10.1126/Science.1176487 |
0.596 |
|
2009 |
Haluszczak C, Akue AD, Hamilton SE, Johnson LD, Pujanauski L, Teodorovic L, Jameson SC, Kedl RM. The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion. The Journal of Experimental Medicine. 206: 435-48. PMID 19188498 DOI: 10.1084/Jem.20081829 |
0.595 |
|
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