| Year |
Citation |
Score |
| 2024 |
Mühlenbeck H, Tsutsui Y, Lemmon MA, Bender KW, Zipfel C. Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling. Elife. 12. PMID 39028038 DOI: 10.7554/eLife.92110 |
0.429 |
|
| 2023 |
Mudumbi KC, Burns EA, Schodt DJ, Petrova ZO, Kiyatkin A, Kim LW, Mangiacapre EM, Ortiz-Caraveo I, Rivera Ortiz H, Hu C, Ashtekar KD, Lidke KA, Lidke DS, Lemmon MA. Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes. Cell Reports. 43: 113603. PMID 38117650 DOI: 10.1016/j.celrep.2023.113603 |
0.838 |
|
| 2023 |
Chongsaritsinsuk J, Steigmeyer AD, Mahoney KE, Rosenfeld MA, Lucas TM, Smith CM, Li A, Ince D, Kearns FL, Battison AS, Hollenhorst MA, Judy Shon D, Tiemeyer KH, Attah V, Kwon C, ... ... Lemmon MA, et al. Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE. Nature Communications. 14: 6169. PMID 37794035 DOI: 10.1038/s41467-023-41756-y |
0.697 |
|
| 2023 |
Mühlenbeck H, Tsutsui Y, Lemmon MA, Bender KW, Zipfel C. Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling. Biorxiv : the Preprint Server For Biology. PMID 37662281 DOI: 10.1101/2023.08.23.554490 |
0.418 |
|
| 2023 |
Berko ER, Witek GM, Matkar S, Petrova ZO, Wu MA, Smith CM, Daniels A, Kalna J, Kennedy A, Gostuski I, Casey C, Krytska K, Gerelus M, Pavlick D, Ghazarian S, ... ... Lemmon MA, et al. Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma. Nature Communications. 14: 2601. PMID 37147298 DOI: 10.1038/s41467-023-38195-0 |
0.64 |
|
| 2023 |
Mudumbi KC, Burns EA, Schodt DJ, Petrova ZO, Kiyatkin A, Kim LW, Mangiacapre EM, Ortiz-Caraveo I, Ortiz HR, Hu C, Ashtekar KD, Lidke KA, Lidke DS, Lemmon MA. Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes. Biorxiv : the Preprint Server For Biology. PMID 37090557 DOI: 10.1101/2023.04.10.536273 |
0.838 |
|
| 2022 |
van Alderwerelt van Rosenburgh IK, Lu DM, Grant MJ, Stayrook SE, Phadke M, Walther Z, Goldberg SB, Politi K, Lemmon MA, Ashtekar KD, Tsutsui Y. Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations. Nature Communications. 13: 6791. PMID 36357385 DOI: 10.1038/s41467-022-34398-z |
0.351 |
|
| 2022 |
Sheetz JB, Lemmon MA. Looking lively: emerging principles of pseudokinase signaling. Trends in Biochemical Sciences. PMID 35585008 DOI: 10.1016/j.tibs.2022.04.011 |
0.815 |
|
| 2022 |
Sheetz JB, Lemmon MA, Tsutsui Y. Dynamics of protein kinases and pseudokinases by HDX-MS. Methods in Enzymology. 667: 303-338. PMID 35525545 DOI: 10.1016/bs.mie.2022.03.037 |
0.804 |
|
| 2022 |
Hu C, Leche CA, Kiyatkin A, Yu Z, Stayrook SE, Ferguson KM, Lemmon MA. Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias. Nature. 602: 518-522. PMID 35140400 DOI: 10.1038/s41586-021-04393-3 |
0.566 |
|
| 2021 |
Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, ... Lemmon MA, et al. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature. 600: 148-152. PMID 34819665 DOI: 10.1038/s41586-021-04141-7 |
0.83 |
|
| 2021 |
Shi F, Mendrola JM, Sheetz JB, Wu N, Sommer A, Speer KF, Noordermeer JN, Kan ZY, Perry K, Englander SW, Stayrook SE, Fradkin LG, Lemmon MA. ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Reports. 37: 109834. PMID 34686333 DOI: 10.1016/j.celrep.2021.109834 |
0.82 |
|
| 2021 |
Smith C, Li A, Krishnamurthy N, Lemmon MA. Phosphatidylserine binding directly regulates TIM-3 function. The Biochemical Journal. PMID 34435619 DOI: 10.1042/BCJ20210425 |
0.719 |
|
| 2021 |
Patil K, Jordan EJ, Park JH, Suresh K, Smith CM, Lemmon AA, Mossé YP, Lemmon MA, Radhakrishnan R. Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33674381 DOI: 10.1073/pnas.2019132118 |
0.708 |
|
| 2021 |
Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GM, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, et al. Drugging the 'undruggable' MYCN oncogenic transcription factor: Overcoming previous obstacles to impact childhood cancers. Cancer Research. PMID 33509943 DOI: 10.1158/0008-5472.CAN-20-3108 |
0.576 |
|
| 2020 |
Artim SC, Kiyatkin A, Lemmon MA. Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB. The Biochemical Journal. PMID 33043964 DOI: 10.1042/BCJ20200695 |
0.395 |
|
| 2020 |
Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, Lemmon MA. Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics. Science Signaling. 13. PMID 32817373 DOI: 10.1126/Scisignal.Aaz5267 |
0.665 |
|
| 2020 |
Sheetz JB, Mathea S, Karvonen H, Malhotra K, Chatterjee D, Niininen W, Perttilä R, Preuss F, Suresh K, Stayrook SE, Tsutsui Y, Radhakrishnan R, Ungureanu D, Knapp S, Lemmon MA. Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Molecular Cell. PMID 32619402 DOI: 10.1016/J.Molcel.2020.06.018 |
0.848 |
|
| 2020 |
Ferguson KM, Hu C, Lemmon MA. Insulin and EGF receptor family members share parallel activation mechanisms. Protein Science : a Publication of the Protein Society. PMID 32297376 DOI: 10.1002/Pro.3871 |
0.654 |
|
| 2020 |
Starrett JH, Guernet AA, Cuomo ME, Poels KE, van Alderwerelt van Rosenburgh IK, Nagelberg A, Farnsworth D, Price KS, Khan H, Ashtekar KD, Gaefele M, Ayeni D, Stewart TF, Kuhlmann A, Kaech S, ... ... Lemmon MA, et al. Drug sensitivity and allele-specificity of first-line osimertinib resistance EGFR mutations. Cancer Research. PMID 32193290 DOI: 10.1158/0008-5472.Can-19-3819 |
0.32 |
|
| 2019 |
Truini A, Starrett JH, Stewart TF, Ashtekar KD, Walther Z, Wurtz A, Lu D, Park JH, DeVeaux M, Song X, Gettinger S, Zelterman D, Lemmon MA, Goldberg SB, Politi K. The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31182434 DOI: 10.1158/1078-0432.Ccr-19-0780 |
0.361 |
|
| 2019 |
Jordan EJ, Patil K, Suresh K, Park JH, Mosse YP, Lemmon MA, Radhakrishnan R. Computational algorithms for in silico profiling of activating mutations in cancer. Cellular and Molecular Life Sciences : Cmls. PMID 30982079 DOI: 10.1007/S00018-019-03097-2 |
0.379 |
|
| 2019 |
Speer KF, Sommer A, Tajer B, Mullins MC, Klein PS, Lemmon MA. Non-acylated Wnts Can Promote Signaling. Cell Reports. 26: 875-883.e5. PMID 30673610 DOI: 10.1016/J.Celrep.2018.12.104 |
0.459 |
|
| 2018 |
Sheetz JB, Lemmon MA. Flipping ATP to AMPlify Kinase Functions. Cell. 175: 641-642. PMID 30340038 DOI: 10.1016/J.Cell.2018.10.011 |
0.799 |
|
| 2018 |
Emptage RP, Lemmon MA, Ferguson KM, Marmorstein R. Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. Structure (London, England : 1993). 26: 1137-1143.e3. PMID 30099988 DOI: 10.1016/J.Str.2018.05.008 |
0.548 |
|
| 2018 |
Liu L, Thaker TM, Freed DM, Frazier N, Malhotra K, Lemmon MA, Jura N. Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure (London, England : 1993). PMID 29358026 DOI: 10.1016/J.Str.2017.12.012 |
0.502 |
|
| 2018 |
Lee S, Choi J, Mohanty J, Sousa LP, Tome F, Pardon E, Steyaert J, Lemmon MA, Lax I, Schlessinger J. Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature. PMID 29342135 DOI: 10.1038/nature25010 |
0.492 |
|
| 2017 |
Freed DM, Bessman NJ, Kiyatkin A, Salazar-Cavazos E, Byrne PO, Moore JO, Valley CC, Ferguson KM, Leahy DJ, Lidke DS, Lemmon MA. EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell. PMID 28988771 DOI: 10.1016/J.Cell.2017.09.017 |
0.468 |
|
| 2017 |
Moore JO, Lemmon MA, Ferguson KM. Dimerization of Tie2 mediated by its membrane-proximal FNIII domains. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396397 DOI: 10.1073/Pnas.1617800114 |
0.545 |
|
| 2016 |
Emptage RP, Lemmon MA, Ferguson KM. Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase. The Biochemical Journal. PMID 27879374 DOI: 10.1042/Bcj20160792 |
0.572 |
|
| 2016 |
Novotny CJ, Pollari S, Park JH, Lemmon MA, Shen W, Shokat KM. Overcoming resistance to HER2 inhibitors through state-specific kinase binding. Nature Chemical Biology. 12: 923-930. PMID 27595329 DOI: 10.1038/Nchembio.2171 |
0.431 |
|
| 2016 |
Freed DM, Park JH, Radhakrishnan R, Lemmon MA. Deletion Mutations Keep Kinase Inhibitors in the Loop. Cancer Cell. 29: 423-5. PMID 27070691 DOI: 10.1016/J.Ccell.2016.03.017 |
0.36 |
|
| 2016 |
Lemmon MA, Freed DM, Schlessinger J, Kiyatkin A. The Dark Side of Cell Signaling: Positive Roles for Negative Regulators. Cell. 164: 1172-1184. PMID 26967284 DOI: 10.1016/J.Cell.2016.02.047 |
0.52 |
|
| 2016 |
Novotny CJ, Pollari S, Park JH, Lemmon MA, Schultz PG, Shen W, Shokat KM. Abstract 3904: Overcoming resistance to HER2 inhibitors through cell based screening Cancer Research. 76: 3904-3904. DOI: 10.1158/1538-7445.Am2016-3904 |
0.387 |
|
| 2015 |
Infarinato NR, Park JH, Krytska K, Ryles HT, Sano R, Szigety KM, Li Y, Zou HY, Lee NV, Smeal T, Lemmon MA, Mosse YP. The ALK/ROS1 inhibitor PF-06463922 overcomes primary resistance to crizotinib in ALK-driven neuroblastoma. Cancer Discovery. PMID 26554404 DOI: 10.1158/2159-8290.Cd-15-1056 |
0.318 |
|
| 2015 |
Ganetzky R, Finn E, Bagchi A, Zollo O, Conlin L, Deardorff M, Harr M, Simpson MA, McGrath JA, Zackai E, Lemmon MA, Sondheimer N. EGFR mutations cause a lethal syndrome of epithelial dysfunction with progeroid features. Molecular Genetics & Genomic Medicine. 3: 452-8. PMID 26436111 DOI: 10.1002/Mgg3.156 |
0.481 |
|
| 2015 |
Freed DM, Alvarado D, Lemmon MA. Ligand regulation of a constitutively dimeric EGF receptor. Nature Communications. 6: 7380. PMID 26060020 DOI: 10.1038/Ncomms8380 |
0.532 |
|
| 2015 |
Moravcevic K, Alvarado D, Schmitz KR, Kenniston JA, Mendrola JM, Ferguson KM, Lemmon MA. Comparison of Saccharomyces cerevisiae F-BAR domain structures reveals a conserved inositol phosphate binding site. Structure (London, England : 1993). 23: 352-63. PMID 25620000 DOI: 10.1016/J.Str.2014.12.009 |
0.807 |
|
| 2015 |
Infarinato N, Park J, Sano R, Krytska K, Ryles H, Zou H, Lee N, Smeal T, Lemmon MA, Mosse YP. Abstract 1619: The next-generation ALK inhibitor PF-06463922 overcomes primary resistance to crizotinib in neuroblastoma Cancer Research. 75: 1619-1619. DOI: 10.1158/1538-7445.Am2015-1619 |
0.372 |
|
| 2015 |
Jordan EJ, Huwe PJ, Mosse Y, Lemmon M, Radhakrishnan R. Predicting the Effects of Clinically Observed Kinase Mutations using Molecular Modeling and Machine Learning Algorithms Biophysical Journal. 108: 376a. DOI: 10.1016/J.Bpj.2014.11.2063 |
0.401 |
|
| 2014 |
Bresler SC, Weiser DA, Huwe PJ, Park JH, Krytska K, Ryles H, Laudenslager M, Rappaport EF, Wood AC, McGrady PW, Hogarty MD, London WB, Radhakrishnan R, Lemmon MA, Mossé YP. ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma. Cancer Cell. 26: 682-94. PMID 25517749 DOI: 10.1016/J.Ccell.2014.09.019 |
0.71 |
|
| 2014 |
Bessman NJ, Freed DM, Lemmon MA. Putting together structures of epidermal growth factor receptors. Current Opinion in Structural Biology. 29: 95-101. PMID 25460273 DOI: 10.1016/J.Sbi.2014.10.002 |
0.493 |
|
| 2014 |
Bessman NJ, Bagchi A, Ferguson KM, Lemmon MA. Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor. Cell Reports. 9: 1306-17. PMID 25453753 DOI: 10.1016/J.Celrep.2014.10.010 |
0.464 |
|
| 2014 |
Fayngerts SA, Wu J, Oxley CL, Liu X, Vourekas A, Cathopoulis T, Wang Z, Cui J, Liu S, Sun H, Lemmon MA, Zhang L, Shi Y, Chen YH. TIPE3 is the transfer protein of lipid second messengers that promote cancer. Cancer Cell. 26: 465-78. PMID 25242044 DOI: 10.1016/J.Ccr.2014.07.025 |
0.321 |
|
| 2014 |
Lemmon MA, Schlessinger J, Ferguson KM. The EGFR family: not so prototypical receptor tyrosine kinases. Cold Spring Harbor Perspectives in Biology. 6: a020768. PMID 24691965 DOI: 10.1101/Cshperspect.A020768 |
0.642 |
|
| 2014 |
Bagchi A, Bessman NJ, Wu NZ, Raines L, Kan Z, Hu W, Englander SW, Leahy DJ, Lemmon MA, Ferguson KM. Allosteric Regulation of the Epidermal Growth Factor Receptor Biophysical Journal. 106: 105a. DOI: 10.1016/J.Bpj.2013.11.650 |
0.477 |
|
| 2013 |
Red Brewer M, Yun CH, Lai D, Lemmon MA, Eck MJ, Pao W. Mechanism for activation of mutated epidermal growth factor receptors in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: E3595-604. PMID 24019492 DOI: 10.1073/Pnas.1220050110 |
0.464 |
|
| 2013 |
Mendrola JM, Shi F, Park JH, Lemmon MA. Receptor tyrosine kinases with intracellular pseudokinase domains. Biochemical Society Transactions. 41: 1029-36. PMID 23863174 DOI: 10.1042/Bst20130104 |
0.709 |
|
| 2013 |
Brewer MLR, Lai D, Lemmon MA, Pao W. Abstract 1106: Mechanism for activation of mutated EGF receptors in lung cancer. Cancer Research. 73: 1106-1106. DOI: 10.1158/1538-7445.Am2013-1106 |
0.401 |
|
| 2013 |
Huwe PJ, Bresler S, Park J, Lemmon M, Radhakrishnan R. Understanding Kinase Activation of ALK in Neuroblastoma Patients Biophysical Journal. 104: 662a. DOI: 10.1016/J.Bpj.2012.11.3654 |
0.737 |
|
| 2013 |
Moore JO, Lemmon MA, Ferguson KM. Tie2 Receptor Dimerization Mediated by its Extracellular FNIII Domains Biophysical Journal. 104: 608a. DOI: 10.1016/J.Bpj.2012.11.3370 |
0.567 |
|
| 2012 |
Park JH, Liu Y, Lemmon MA, Radhakrishnan R. Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain. The Biochemical Journal. 448: 417-23. PMID 23101586 DOI: 10.1042/Bj20121513 |
0.52 |
|
| 2012 |
Artim SC, Mendrola JM, Lemmon MA. Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family. The Biochemical Journal. 448: 213-20. PMID 22992069 DOI: 10.1042/Bj20121365 |
0.532 |
|
| 2012 |
Park JH, Lemmon MA. Occupy EGFR. Cancer Discovery. 2: 398-400. PMID 22588876 DOI: 10.1158/2159-8290.Cd-12-0144 |
0.419 |
|
| 2012 |
Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, ... ... Lemmon MA, et al. Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma. Oncogene. 31: 4859-67. PMID 22266870 DOI: 10.1038/Onc.2011.647 |
0.714 |
|
| 2012 |
Bessman NJ, Lemmon MA. Finding the missing links in EGFR. Nature Structural & Molecular Biology. 19: 1-3. PMID 22218287 DOI: 10.1038/Nsmb.2221 |
0.41 |
|
| 2012 |
Moravcevic K, Oxley CL, Lemmon MA. Conditional peripheral membrane proteins: facing up to limited specificity. Structure (London, England : 1993). 20: 15-27. PMID 22193136 DOI: 10.1016/J.Str.2011.11.012 |
0.826 |
|
| 2012 |
Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, ... ... Lemmon MA, et al. Erratum: Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma Oncogene. 31: 4888-4888. DOI: 10.1038/Onc.2012.208 |
0.668 |
|
| 2011 |
Bresler SC, Wood AC, Haglund EA, Courtright J, Belcastro LT, Plegaria JS, Cole K, Toporovskaya Y, Zhao H, Carpenter EL, Christensen JG, Maris JM, Lemmon MA, Mossé YP. Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma. Science Translational Medicine. 3: 108ra114. PMID 22072639 DOI: 10.1126/Scitranslmed.3002950 |
0.73 |
|
| 2011 |
Watt B, Tenza D, Lemmon MA, Kerje S, Raposo G, Andersson L, Marks MS. Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic. Plos Genetics. 7: e1002286. PMID 21949659 DOI: 10.1371/Journal.Pgen.1002286 |
0.327 |
|
| 2011 |
Shi F, Lemmon MA. Biochemistry. KSR plays CRAF-ty. Science (New York, N.Y.). 332: 1043-4. PMID 21617065 DOI: 10.1126/Science.1208063 |
0.617 |
|
| 2011 |
Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases. The Biochemical Journal. 436: 241-51. PMID 21426301 DOI: 10.1042/Bj20101791 |
0.44 |
|
| 2011 |
Kazanietz MG, Lemmon MA. Protein kinase C regulation: C1 meets C-tail. Structure (London, England : 1993). 19: 144-6. PMID 21300283 DOI: 10.1016/J.Str.2011.01.004 |
0.411 |
|
| 2011 |
Bresler SC, Wood A, Haglund E, Christensen J, Maris JM, Lemmon MA, Mosse YP. Abstract 4685: Mechanistic guidance of ALK inhibition for the treatment of neuroblastoma Cancer Research. 71: 4685-4685. DOI: 10.1158/1538-7445.Am2011-4685 |
0.756 |
|
| 2011 |
Carpenter EL, Haglund EA, Chow AK, Wood AC, Belcastro LT, Christensen JG, Vigny M, Maris JM, Lemmon MA, Mosse YP. Abstract 4563: Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma Cancer Research. 71: 4563-4563. DOI: 10.1158/1538-7445.Am2011-4563 |
0.352 |
|
| 2010 |
Sosa MS, Lopez-Haber C, Yang C, Wang H, Lemmon MA, Busillo JM, Luo J, Benovic JL, Klein-Szanto A, Yagi H, Gutkind JS, Parsons RE, Kazanietz MG. Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. Molecular Cell. 40: 877-92. PMID 21172654 DOI: 10.1016/J.Molcel.2010.11.029 |
0.356 |
|
| 2010 |
Moravcevic K, Mendrola JM, Schmitz KR, Wang YH, Slochower D, Janmey PA, Lemmon MA. Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids Cell. 143: 966-977. PMID 21145462 DOI: 10.1016/J.Cell.2010.11.028 |
0.847 |
|
| 2010 |
Alvarado D, Klein DE, Lemmon MA. Structural basis for negative cooperativity in growth factor binding to an EGF receptor. Cell. 142: 568-79. PMID 20723758 DOI: 10.1016/J.Cell.2010.07.015 |
0.699 |
|
| 2010 |
Kenniston JA, Lemmon MA. Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients. The Embo Journal. 29: 3054-67. PMID 20700106 DOI: 10.1038/Emboj.2010.187 |
0.51 |
|
| 2010 |
Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 141: 1117-34. PMID 20602996 DOI: 10.1016/J.Cell.2010.06.011 |
0.639 |
|
| 2010 |
Shi F, Telesco SE, Liu Y, Radhakrishnan R, Lemmon MA. ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 107: 7692-7. PMID 20351256 DOI: 10.1073/Pnas.1002753107 |
0.735 |
|
| 2010 |
Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Conserved Hydrophobic and Hydrophilic Bond Interaction Networks in ErbB Family Kinases Biophysical Journal. 98: 445a. DOI: 10.1016/J.Bpj.2009.12.2417 |
0.407 |
|
| 2009 |
Watt B, van Niel G, Fowler DM, Hurbain I, Luk KC, Stayrook SE, Lemmon MA, Raposo G, Shorter J, Kelly JW, Marks MS. N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. The Journal of Biological Chemistry. 284: 35543-55. PMID 19840945 DOI: 10.1074/Jbc.M109.047449 |
0.377 |
|
| 2009 |
Szentpetery Z, Balla A, Kim YJ, Lemmon MA, Balla T. Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study. Bmc Cell Biology. 10: 67. PMID 19769794 DOI: 10.1186/1471-2121-10-67 |
0.444 |
|
| 2009 |
Alvarado D, Klein DE, Lemmon MA. ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor. Nature. 461: 287-91. PMID 19718021 DOI: 10.1038/Nature08297 |
0.683 |
|
| 2009 |
Bethoney KA, King MC, Hinshaw JE, Ostap EM, Lemmon MA. A possible effector role for the pleckstrin homology (PH) domain of dynamin. Proceedings of the National Academy of Sciences of the United States of America. 106: 13359-64. PMID 19666604 DOI: 10.1073/Pnas.0906945106 |
0.818 |
|
| 2009 |
Red Brewer M, Choi SH, Alvarado D, Moravcevic K, Pozzi A, Lemmon MA, Carpenter G. The juxtamembrane region of the EGF receptor functions as an activation domain. Molecular Cell. 34: 641-51. PMID 19560417 DOI: 10.1016/J.Molcel.2009.04.034 |
0.839 |
|
| 2009 |
Nishihama R, Schreiter JH, Onishi M, Vallen EA, Hanna J, Moravcevic K, Lippincott MF, Han H, Lemmon MA, Pringle JR, Bi E. Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae. The Journal of Cell Biology. 185: 995-1012. PMID 19528296 DOI: 10.1083/Jcb.200903125 |
0.814 |
|
| 2009 |
Lian L, Wang Y, Flick M, Choi J, Scott EW, Degen J, Lemmon MA, Abrams CS. Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis. Blood. 113: 3577-84. PMID 19190246 DOI: 10.1182/Blood-2008-09-178913 |
0.36 |
|
| 2009 |
Wilson KJ, Gilmore JL, Foley J, Lemmon MA, Riese DJ. Functional selectivity of EGF family peptide growth factors: implications for cancer. Pharmacology & Therapeutics. 122: 1-8. PMID 19135477 DOI: 10.1016/J.Pharmthera.2008.11.008 |
0.718 |
|
| 2009 |
Lemmon MA. Ligand-induced ErbB receptor dimerization. Experimental Cell Research. 315: 638-48. PMID 19038249 DOI: 10.1016/J.Yexcr.2008.10.024 |
0.465 |
|
| 2008 |
Klein DE, Stayrook SE, Shi F, Narayan K, Lemmon MA. Structural basis for EGFR ligand sequestration by Argos. Nature. 453: 1271-5. PMID 18500331 DOI: 10.1038/Nature06978 |
0.796 |
|
| 2008 |
Qiu C, Tarrant MK, Choi SH, Sathyamurthy A, Bose R, Banjade S, Pal A, Bornmann WG, Lemmon MA, Cole PA, Leahy DJ. Mechanism of activation and inhibition of the HER4/ErbB4 kinase. Structure (London, England : 1993). 16: 460-7. PMID 18334220 DOI: 10.1016/J.Str.2007.12.016 |
0.514 |
|
| 2008 |
Lemmon MA. Membrane recognition by phospholipid-binding domains. Nature Reviews. Molecular Cell Biology. 9: 99-111. PMID 18216767 DOI: 10.1038/Nrm2328 |
0.437 |
|
| 2007 |
Dawson JP, Bu Z, Lemmon MA. Ligand-induced structural transitions in ErbB receptor extracellular domains. Structure (London, England : 1993). 15: 942-54. PMID 17697999 DOI: 10.1016/J.Str.2007.06.013 |
0.753 |
|
| 2007 |
Lemmon MA, Ferguson KM. A new twist in the transmembrane signaling tool-kit. Cell. 130: 213-5. PMID 17662934 DOI: 10.1016/J.Cell.2007.07.006 |
0.456 |
|
| 2007 |
Lemmon MA. Pleckstrin homology (PH) domains and phosphoinositides. Biochemical Society Symposium. 81-93. PMID 17233582 DOI: 10.1042/Bss0740081 |
0.509 |
|
| 2007 |
Wang Y, Lian L, Flick M, Degen J, Lemmon M, Abrams CS. Mice Lacking Pleckstrin or Pleckstrin-2 Each Have Unique Platelet Secretion Defects. Blood. 110: 134-134. DOI: 10.1182/Blood.V110.11.134.134 |
0.307 |
|
| 2007 |
Lemmon MA. Activation and Inhibition of the EGF Receptor The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A46-B |
0.372 |
|
| 2006 |
Schlessinger J, Lemmon MA. Nuclear signaling by receptor tyrosine kinases: the first robin of spring. Cell. 127: 45-8. PMID 17018275 DOI: 10.1016/J.Cell.2006.09.013 |
0.583 |
|
| 2006 |
Baumeister MA, Rossman KL, Sondek J, Lemmon MA. The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity. The Biochemical Journal. 400: 563-72. PMID 17007612 DOI: 10.1042/Bj20061020 |
0.831 |
|
| 2006 |
Choi SH, Mendrola JM, Lemmon MA. EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer. Oncogene. 26: 1567-76. PMID 16953218 DOI: 10.1038/Sj.Onc.1209957 |
0.484 |
|
| 2006 |
Choudhury P, Srivastava S, Li Z, Ko K, Albaqumi M, Narayan K, Coetzee WA, Lemmon MA, Skolnik EY. Specificity of the myotubularin family of phosphatidylinositol-3-phosphatase is determined by the PH/GRAM domain. The Journal of Biological Chemistry. 281: 31762-9. PMID 16914545 DOI: 10.1074/Jbc.M606344200 |
0.761 |
|
| 2006 |
Alvarado D, Evans TA, Sharma R, Lemmon MA, Duffy JB. Argos mutants define an affinity threshold for spitz inhibition in vivo. The Journal of Biological Chemistry. 281: 28993-9001. PMID 16870613 DOI: 10.1074/Jbc.M603782200 |
0.463 |
|
| 2006 |
Narayan K, Lemmon MA. Determining selectivity of phosphoinositide-binding domains. Methods (San Diego, Calif.). 39: 122-33. PMID 16829131 DOI: 10.1016/J.Ymeth.2006.05.006 |
0.492 |
|
| 2006 |
Ozcan F, Klein P, Lemmon MA, Lax I, Schlessinger J. On the nature of low- and high-affinity EGF receptors on living cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 5735-40. PMID 16571657 DOI: 10.1073/Pnas.0601469103 |
0.606 |
|
| 2006 |
Miura GI, Buglino J, Alvarado D, Lemmon MA, Resh MD, Treisman JE. Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. Developmental Cell. 10: 167-76. PMID 16459296 DOI: 10.1016/J.Devcel.2005.11.017 |
0.432 |
|
| 2006 |
Yang C, Liu Y, Lemmon MA, Kazanietz MG. Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4. Molecular and Cellular Biology. 26: 831-42. PMID 16428439 DOI: 10.1128/Mcb.26.3.831-842.2006 |
0.443 |
|
| 2006 |
Michell RH, Heath VL, Lemmon MA, Dove SK. Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions. Trends in Biochemical Sciences. 31: 52-63. PMID 16364647 DOI: 10.1016/J.Tibs.2005.11.013 |
0.355 |
|
| 2006 |
Lian L, Wang Y, Chen X, Bach T, Lenox L, Zhu P, Flick M, Scott E, Degen J, Freedman B, Koretzky G, Lemmon M, Abrams CS. Knockout of the PKC Substrate Pleckstrin Causes Pleomorphic Defects in Platelets, Lymphocytes and Granulocytes. Blood. 108: 394-394. DOI: 10.1182/Blood.V108.11.394.394 |
0.326 |
|
| 2005 |
Dawson JP, Berger MB, Lin CC, Schlessinger J, Lemmon MA, Ferguson KM. Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface. Molecular and Cellular Biology. 25: 7734-42. PMID 16107719 DOI: 10.1128/Mcb.25.17.7734-7742.2005 |
0.825 |
|
| 2005 |
Reeves GT, Kalifa R, Klein DE, Lemmon MA, Shvartsman SY. Computational analysis of EGFR inhibition by Argos. Developmental Biology. 284: 523-35. PMID 15982648 DOI: 10.1016/J.Ydbio.2005.05.013 |
0.646 |
|
| 2005 |
Lemmon MA. Pleckstrin homology domains: two halves make a hole? Cell. 120: 574-6. PMID 15766521 DOI: 10.1016/J.Cell.2005.02.023 |
0.449 |
|
| 2005 |
Flesch FM, Yu JW, Lemmon MA, Burger KN. Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain. The Biochemical Journal. 389: 435-41. PMID 15755258 DOI: 10.1042/Bj20041721 |
0.574 |
|
| 2005 |
Lemmon MA. Pleckstrin homology domains: not just for phosphoinositides. Biochemical Society Transactions. 32: 707-11. PMID 15493994 DOI: 10.1042/Bst0320707 |
0.502 |
|
| 2004 |
Klein DE, Nappi VM, Reeves GT, Shvartsman SY, Lemmon MA. Argos inhibits epidermal growth factor receptor signalling by ligand sequestration. Nature. 430: 1040-4. PMID 15329724 DOI: 10.1038/Nature02840 |
0.687 |
|
| 2004 |
Berger MB, Mendrola JM, Lemmon MA. ErbB3/HER3 does not homodimerize upon neuregulin binding at the cell surface. Febs Letters. 569: 332-6. PMID 15225657 DOI: 10.1016/J.Febslet.2004.06.014 |
0.729 |
|
| 2004 |
King MC, Raposo G, Lemmon MA. Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB. Proceedings of the National Academy of Sciences of the United States of America. 101: 8957-62. PMID 15184662 DOI: 10.1073/Pnas.0403167101 |
0.312 |
|
| 2004 |
Dove SK, Piper RC, McEwen RK, Yu JW, King MC, Hughes DC, Thuring J, Holmes AB, Cooke FT, Michell RH, Parker PJ, Lemmon MA. Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. The Embo Journal. 23: 1922-33. PMID 15103325 DOI: 10.1038/Sj.Emboj.7600203 |
0.469 |
|
| 2004 |
Yu JW, Mendrola JM, Audhya A, Singh S, Keleti D, DeWald DB, Murray D, Emr SD, Lemmon MA. Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. Molecular Cell. 13: 677-88. PMID 15023338 DOI: 10.1016/S1097-2765(04)00083-8 |
0.611 |
|
| 2004 |
Wild AC, Yu JW, Lemmon MA, Blumer KJ. The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate. The Journal of Biological Chemistry. 279: 17101-10. PMID 14766750 DOI: 10.1074/Jbc.M314035200 |
0.62 |
|
| 2004 |
Klein P, Mattoon D, Lemmon MA, Schlessinger J. A structure-based model for ligand binding and dimerization of EGF receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 929-34. PMID 14732694 DOI: 10.1073/Pnas.0307285101 |
0.632 |
|
| 2004 |
Mattoon D, Klein P, Lemmon MA, Lax I, Schlessinger J. The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function. Proceedings of the National Academy of Sciences of the United States of America. 101: 923-8. PMID 14732693 DOI: 10.1073/Pnas.0307286101 |
0.632 |
|
| 2003 |
Lemmon MA. The EGF receptor family as therapeutic targets in breast cancer. Breast Disease. 18: 33-43. PMID 15687687 DOI: 10.3233/Bd-2003-18105 |
0.402 |
|
| 2003 |
Burgess AW, Cho HS, Eigenbrot C, Ferguson KM, Garrett TP, Leahy DJ, Lemmon MA, Sliwkowski MX, Ward CW, Yokoyama S. An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Molecular Cell. 12: 541-52. PMID 14527402 DOI: 10.1016/S1097-2765(03)00350-2 |
0.494 |
|
| 2003 |
Schlessinger J, Lemmon MA. SH2 and PTB domains in tyrosine kinase signaling. Science's Stke : Signal Transduction Knowledge Environment. 2003: RE12. PMID 12865499 DOI: 10.1126/Stke.2003.191.Re12 |
0.645 |
|
| 2003 |
Lemmon MA. Phosphoinositide recognition domains. Traffic (Copenhagen, Denmark). 4: 201-13. PMID 12694559 DOI: 10.1034/J.1600-0854.2004.00071.X |
0.538 |
|
| 2003 |
Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Molecular Cell. 11: 507-17. PMID 12620237 DOI: 10.1016/S1097-2765(03)00047-9 |
0.708 |
|
| 2003 |
Yu JW, Lemmon MA. Genome-wide analysis of signaling domain function. Current Opinion in Chemical Biology. 7: 103-9. PMID 12547434 DOI: 10.1016/S1367-5931(02)00008-X |
0.552 |
|
| 2003 |
Baumeister MA, Martinu L, Rossman KL, Sondek J, Lemmon MA, Chou MM. Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting. The Journal of Biological Chemistry. 278: 11457-64. PMID 12525493 DOI: 10.1074/Jbc.M211901200 |
0.84 |
|
| 2002 |
Saxena A, Morozov P, Frank D, Musalo R, Lemmon MA, Skolnik EY, Tycko B. Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1. The Journal of Biological Chemistry. 277: 49935-44. PMID 12374806 DOI: 10.1074/Jbc.M206497200 |
0.775 |
|
| 2002 |
Aasland R, Abrams C, Ampe C, Ball LJ, Bedford MT, Cesareni G, Gimona M, Hurley JH, Jarchau T, Lehto VP, Lemmon MA, Linding R, Mayer BJ, Nagai M, Sudol M, et al. Normalization of nomenclature for peptide motifs as ligands of modular protein domains. Febs Letters. 513: 141-4. PMID 11911894 DOI: 10.1016/S0014-5793(01)03295-1 |
0.371 |
|
| 2002 |
Lemmon MA, Ferguson KM, Abrams CS. Pleckstrin homology domains and the cytoskeleton. Febs Letters. 513: 71-6. PMID 11911883 DOI: 10.1016/S0014-5793(01)03243-4 |
0.545 |
|
| 2002 |
Mendrola JM, Berger MB, King MC, Lemmon MA. The single transmembrane domains of ErbB receptors self-associate in cell membranes. The Journal of Biological Chemistry. 277: 4704-12. PMID 11741943 DOI: 10.1074/Jbc.M108681200 |
0.736 |
|
| 2001 |
Snyder JT, Rossman KL, Baumeister MA, Pruitt WM, Siderovski DP, Der CJ, Lemmon MA, Sondek J. Quantitative analysis of the effect of phosphoinositide interactions on the function of Dbl family proteins. The Journal of Biological Chemistry. 276: 45868-75. PMID 11577097 DOI: 10.1074/Jbc.M106731200 |
0.829 |
|
| 2001 |
Yu JW, Lemmon MA. All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate. The Journal of Biological Chemistry. 276: 44179-84. PMID 11557775 DOI: 10.1074/Jbc.M108811200 |
0.61 |
|
| 2001 |
Lemmon MA, Ferguson KM. Molecular determinants in pleckstrin homology domains that allow specific recognition of phosphoinositides Biochemical Society Transactions. 29: 377-384. PMID 11497993 DOI: 10.1042/Bst0290377 |
0.505 |
|
| 2001 |
Sankaran VG, Klein DE, Sachdeva MM, Lemmon MA. High-affinity binding of a FYVE domain to phosphatidylinositol 3-phosphate requires intact phospholipid but not FYVE domain oligomerization. Biochemistry. 40: 8581-7. PMID 11456498 DOI: 10.1021/Bi010425D |
0.725 |
|
| 2001 |
Lee A, Lemmon MA. Analysis of phosphoinositide binding by pleckstrin homology domain from dynamin. Methods in Enzymology. 329: 457-68. PMID 11210566 DOI: 10.1016/S0076-6879(01)29107-1 |
0.519 |
|
| 2001 |
Plotnikov AN, Eliseenkova AV, Ibrahimi OA, Shriver Z, Sasisekharan R, Lemmon MA, Mohammadi M. Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition. The Journal of Biological Chemistry. 276: 4322-9. PMID 11060292 DOI: 10.1074/Jbc.M006502200 |
0.372 |
|
| 2001 |
Lemmon MA. Molecular determinants within pleckstrin homology (PH) domains that allow for specific recognition of phosphoinositides Biochemical Society Transactions. 29: A47-A47. DOI: 10.1042/Bst029A047A |
0.435 |
|
| 2000 |
Ferguson KM, Kavran JM, Sankaran VG, Fournier E, Isakoff SJ, Skolnik EY, Lemmon MA. Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Molecular Cell. 6: 373-84. PMID 10983984 DOI: 10.1016/S1097-2765(00)00037-X |
0.505 |
|
| 2000 |
Ferguson KM, Darling PJ, Mohan MJ, Macatee TL, Lemmon MA. Extracellular domains drive homo- but not hetero-dimerization of erbB receptors. The Embo Journal. 19: 4632-43. PMID 10970856 DOI: 10.1093/Emboj/19.17.4632 |
0.518 |
|
| 2000 |
Lemmon MA. Structural basis for high-affinity phosphoinositide binding by pleckstrin homology domains. Biochemical Society Transactions. 27: 617-24. PMID 10917653 DOI: 10.1042/Bst0270617 |
0.475 |
|
| 2000 |
Razzini G, Brancaccio A, Lemmon MA, Guarnieri S, Falasca M. The role of the pleckstrin homology domain in membrane targeting and activation of phospholipase Cbeta(1). The Journal of Biological Chemistry. 275: 14873-81. PMID 10809731 DOI: 10.1074/Jbc.275.20.14873 |
0.399 |
|
| 2000 |
LEMMON MA, FERGUSON KM. Signal-dependent membrane targeting by pleckstrin homology (PH) domains Biochemical Journal. 350: 1-18. DOI: 10.1042/Bj3500001 |
0.525 |
|
| 1999 |
Lee A, Frank DW, Marks MS, Lemmon MA. Dominant-negative inhibition of receptor-mediated endocytosis by a dynamin-1 mutant with a defective pleckstrin homology domain. Current Biology : Cb. 9: 261-4. PMID 10074457 DOI: 10.1016/S0960-9822(99)80115-8 |
0.535 |
|
| 1999 |
Lemmon MA. Structural bases for specific phosphoinositide binding by PH domains Biochemical Society Transactions. 27: A73-A73. DOI: 10.1042/Bst027A073A |
0.478 |
|
| 1998 |
Jost M, Simpson F, Kavran JM, Lemmon MA, Schmid SL. Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation. Current Biology : Cb. 8: 1399-402. PMID 9889104 DOI: 10.1016/S0960-9822(98)00022-0 |
0.425 |
|
| 1998 |
Kavran JM, Klein DE, Lee A, Falasca M, Isakoff SJ, Skolnik EY, Lemmon MA. Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains. The Journal of Biological Chemistry. 273: 30497-508. PMID 9804818 DOI: 10.1074/Jbc.273.46.30497 |
0.707 |
|
| 1998 |
Klein DE, Lee A, Frank DW, Marks MS, Lemmon MA. The pleckstrin homology domains of dynamin isoforms require oligomerization for high affinity phosphoinositide binding. The Journal of Biological Chemistry. 273: 27725-33. PMID 9765310 DOI: 10.1074/Jbc.273.42.27725 |
0.709 |
|
| 1998 |
Isakoff SJ, Cardozo T, Andreev J, Li Z, Ferguson KM, Abagyan R, Lemmon MA, Aronheim A, Skolnik EY. Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast. The Embo Journal. 17: 5374-87. PMID 9736615 DOI: 10.1093/Emboj/17.18.5374 |
0.783 |
|
| 1998 |
Lemmon MA, Schlessinger J. Transmembrane signaling by receptor oligomerization. Methods in Molecular Biology (Clifton, N.J.). 84: 49-71. PMID 9666441 DOI: 10.1385/0-89603-488-7:49 |
0.534 |
|
| 1998 |
Falasca M, Logan SK, Lehto VP, Baccante G, Lemmon MA, Schlessinger J. Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. The Embo Journal. 17: 414-22. PMID 9430633 DOI: 10.1093/Emboj/17.2.414 |
0.632 |
|
| 1998 |
Lemmon MA, Ferguson KM. Pleckstrin homology domains. Current Topics in Microbiology and Immunology. 228: 39-74. PMID 9401202 DOI: 10.1007/978-3-642-80481-6_3 |
0.518 |
|
| 1997 |
Artalejo CR, Lemmon MA, Schlessinger J, Palfrey HC. Specific role for the PH domain of dynamin-1 in the regulation of rapid endocytosis in adrenal chromaffin cells. The Embo Journal. 16: 1565-74. PMID 9130701 DOI: 10.1093/Emboj/16.7.1565 |
0.597 |
|
| 1997 |
Lemmon MA, Pinchasi D, Zhou M, Lax I, Schlessinger J. Kit receptor dimerization is driven by bivalent binding of stem cell factor. The Journal of Biological Chemistry. 272: 6311-7. PMID 9045650 DOI: 10.1074/Jbc.272.10.6311 |
0.647 |
|
| 1997 |
Burke CL, Lemmon MA, Coren BA, Engelman DM, Stern DF. Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformation. Oncogene. 14: 687-96. PMID 9038376 DOI: 10.1038/Sj.Onc.1200873 |
0.677 |
|
| 1997 |
Lemmon MA, Bu Z, Ladbury JE, Zhou M, Pinchasi D, Lax I, Engelman DM, Schlessinger J. Two EGF molecules contribute additively to stabilization of the EGFR dimer. The Embo Journal. 16: 281-94. PMID 9029149 DOI: 10.1093/Emboj/16.2.281 |
0.714 |
|
| 1997 |
Mingarro I, Whitley P, Lemmon MA, von Heijne G. Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix: a rapid way to map helix-helix interactions in integral membrane proteins. Protein Science : a Publication of the Protein Society. 5: 1339-41. PMID 8819166 DOI: 10.1002/Pro.5560050712 |
0.357 |
|
| 1996 |
Lemmon MA, Ferguson KM, Schlessinger J. PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell. 85: 621-4. PMID 8646770 DOI: 10.1016/S0092-8674(00)81022-3 |
0.642 |
|
| 1996 |
Mandiyan V, O'Brien R, Zhou M, Margolis B, Lemmon MA, Sturtevant JM, Schlessinger J. Thermodynamic studies of SHC phosphotyrosine interaction domain recognition of the NPXpY motif. The Journal of Biological Chemistry. 271: 4770-5. PMID 8617744 DOI: 10.1074/Jbc.271.9.4770 |
0.602 |
|
| 1996 |
Zheng J, Cahill SM, Lemmon MA, Fushman D, Schlessinger J, Cowburn D. Identification of the binding site for acidic phospholipids on the pH domain of dynamin: implications for stimulation of GTPase activity. Journal of Molecular Biology. 255: 14-21. PMID 8568861 DOI: 10.1006/Jmbi.1996.0002 |
0.732 |
|
| 1996 |
Ferguson KM, Lemmon MA, Schlessinger J, Sigler PB. PH domains: diverse sequences with a common membrane association function Acta Crystallographica Section a Foundations of Crystallography. 52: C185-C185. DOI: 10.1107/S0108767396091908 |
0.493 |
|
| 1995 |
Ferguson KM, Lemmon MA, Schlessinger J, Sigler PB. Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. Cell. 83: 1037-46. PMID 8521504 DOI: 10.1016/0092-8674(95)90219-8 |
0.623 |
|
| 1995 |
Schlessinger J, Lax I, Lemmon M. Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? Cell. 83: 357-60. PMID 8521464 DOI: 10.1016/0092-8674(95)90112-4 |
0.594 |
|
| 1995 |
Fushman D, Cahill S, Lemmon MA, Schlessinger J, Cowburn D. Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 92: 816-20. PMID 7846058 DOI: 10.1073/Pnas.92.3.816 |
0.71 |
|
| 1995 |
Lee CH, Leung B, Lemmon MA, Zheng J, Cowburn D, Kuriyan J, Saksela K. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein Embo Journal. 14: 5006-5015. PMID 7588629 |
0.597 |
|
| 1995 |
Ferguson KM, Lemmon MA, Sigler PB, Schlessinger J. Scratching the surface with the PH domain. Nature Structural Biology. 2: 715-8. PMID 7552736 DOI: 10.1038/Nsb0995-715 |
0.612 |
|
| 1995 |
Ladbury JE, Lemmon MA, Zhou M, Green J, Botfield MC, Schlessinger J. Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. Proceedings of the National Academy of Sciences of the United States of America. 92: 3199-203. PMID 7536927 DOI: 10.1073/Pnas.92.8.3199 |
0.647 |
|
| 1995 |
Lemmon MA, Ferguson KM, O'Brien R, Sigler PB, Schlessinger J. Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain. Proceedings of the National Academy of Sciences of the United States of America. 92: 10472-6. PMID 7479822 DOI: 10.1073/Pnas.92.23.10472 |
0.63 |
|
| 1995 |
Lee C, Leung B, Lemmon MA, Zheng J, Cowburn D, Kuriyan J, Saksela K. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein The Embo Journal. 14: 5006-5015. DOI: 10.1002/J.1460-2075.1995.Tb00183.X |
0.638 |
|
| 1994 |
Lemmon MA, Engelman DM. Specificity and promiscuity in membrane helix interactions. Febs Letters. 346: 17-20. PMID 8206151 DOI: 10.1016/0014-5793(94)00467-6 |
0.56 |
|
| 1994 |
Sorokin A, Lemmon MA, Ullrich A, Schlessinger J. Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond. The Journal of Biological Chemistry. 269: 9752-9. PMID 8144568 |
0.573 |
|
| 1994 |
Lemmon MA, Engelman DM. Specificity and promiscuity in membrane helix interactions. Quarterly Reviews of Biophysics. 27: 157-218. PMID 7984776 DOI: 10.1017/S0033583500004522 |
0.588 |
|
| 1994 |
Ferguson KM, Lemmon MA, Schlessinger J, Sigler PB. Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin. Cell. 79: 199-209. PMID 7954789 DOI: 10.1016/0092-8674(94)90190-2 |
0.591 |
|
| 1994 |
Lemmon MA, Schlessinger J. Regulation of signal transduction and signal diversity by receptor oligomerization. Trends in Biochemical Sciences. 19: 459-63. PMID 7855887 DOI: 10.1016/0968-0004(94)90130-9 |
0.63 |
|
| 1994 |
Lemmon MA, Treutlein HR, Adams PD, Brünger AT, Engelman DM. A dimerization motif for transmembrane alpha-helices. Nature Structural Biology. 1: 157-63. PMID 7656033 DOI: 10.1038/Nsb0394-157 |
0.58 |
|
| 1994 |
Spivak-Kroizman T, Lemmon MA, Dikic I, Ladbury JE, Pinchasi D, Huang J, Jaye M, Crumley G, Schlessinger J, Lax I. Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation. Cell. 79: 1015-24. PMID 7528103 DOI: 10.1016/0092-8674(94)90032-9 |
0.705 |
|
| 1994 |
Lemmon MA, Ladbury JE, Mandiyan V, Zhou M, Schlessinger J. Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2. The Journal of Biological Chemistry. 269: 31653-8. PMID 7527391 |
0.605 |
|
| 1994 |
Arkin IT, Adams PD, MacKenzie KR, Lemmon MA, Brünger AT, Engelman DM. Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel. The Embo Journal. 13: 4757-64. PMID 7525269 DOI: 10.1002/J.1460-2075.1994.Tb06801.X |
0.591 |
|
| 1994 |
Lemmon MA, Ladbury JE. Thermodynamic studies of tyrosyl-phosphopeptide binding to the SH2 domain of p56lck. Biochemistry. 33: 5070-6. PMID 7513553 DOI: 10.1021/Bi00183A010 |
0.534 |
|
| 1993 |
Engelman DM, Adair BD, Brünger A, Flanagan JM, Hunt JF, Lemmon MA, Treutlein H, Zhang J. Dimerization of glycophorin A transmembrane helices: mutagenesis and modeling. Society of General Physiologists Series. 48: 11-21. PMID 8503039 |
0.483 |
|
| 1993 |
Engelman DM, Adair BD, Brunger A, Flanagan JM, Hunt JF, Lemmon MA, Treutlein H, Zhang J. Dimerization of glycophorin A transmembrane helices: Mutagenesis and modeling Journal of General Physiology. 101: 11-21. DOI: 10.1007/978-94-011-2718-9_11 |
0.645 |
|
| 1992 |
Lemmon MA, Flanagan JM, Hunt JF, Adair BD, Bormann BJ, Dempsey CE, Engelman DM. Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices. The Journal of Biological Chemistry. 267: 7683-9. PMID 1560003 |
0.55 |
|
| 1992 |
Treutlein HR, Lemmon MA, Engelman DM, Brünger AT. The glycophorin A transmembrane domain dimer: sequence-specific propensity for a right-handed supercoil of helices. Biochemistry. 31: 12726-32. PMID 1463744 DOI: 10.1021/Bi00166A003 |
0.58 |
|
| 1992 |
Lemmon MA, Flanagan JM, Treutlein HR, Zhang J, Engelman DM. Sequence specificity in the dimerization of transmembrane α-helices Biochemistry. 31: 12719-12725. PMID 1463743 DOI: 10.1021/Bi00166A002 |
0.577 |
|
| 1992 |
Lemmon MA, Engelman DM. Helix-helix interactions inside lipid bilayers Current Opinion in Structural Biology. 2: 511-518. DOI: 10.1016/0959-440X(92)90080-Q |
0.58 |
|
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