Wyndham W. Lathem, Ph.D. - Publications

Affiliations: 
2003 University of Wisconsin, Madison, Madison, WI 
Area:
Microbiology Biology, Pathology, Public Health

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ritzert JT, Lathem WW. Depletion of Glucose Activates Catabolite Repression during Pneumonic Plague. Journal of Bacteriology. PMID 29555700 DOI: 10.1128/Jb.00737-17  0.349
2016 Eddy JL, Schroeder JA, Zimbler DL, Caulfield AJ, Lathem WW. Proteolysis of plasminogen activator inhibitor-1 by Yersinia pestis remodulates the host environment to promote virulence. Journal of Thrombosis and Haemostasis : Jth. PMID 27377187 DOI: 10.1111/Jth.13408  0.411
2015 Zimbler DL, Eddy JL, Schroeder JA, Lathem WW. Inactivation of peroxiredoxin 6 by the Pla protease of Yersinia pestis. Infection and Immunity. PMID 26553463 DOI: 10.1128/Iai.01168-15  0.374
2015 Eddy JL, Schroeder JA, Zimbler DL, Bellows LE, Lathem WW. Impact of the Pla protease substrate α2-antiplasmin on the progression of primary pneumonic plague. Infection and Immunity. PMID 26438794 DOI: 10.1128/Iai.01086-15  0.358
2015 Zimbler DL, Schroeder JA, Eddy JL, Lathem WW. Early emergence of Yersinia pestis as a severe respiratory pathogen. Nature Communications. 6: 7487. PMID 26123398 DOI: 10.1038/Ncomms8487  0.373
2014 Eddy JL, Gielda LM, Caulfield AJ, Rangel SM, Lathem WW. Production of outer membrane vesicles by the plague pathogen Yersinia pestis. Plos One. 9: e107002. PMID 25198697 DOI: 10.1371/Journal.Pone.0107002  0.357
2014 Caulfield AJ, Lathem WW. Disruption of fas-fas ligand signaling, apoptosis, and innate immunity by bacterial pathogens. Plos Pathogens. 10: e1004252. PMID 25101900 DOI: 10.1371/Journal.Ppat.1004252  0.321
2014 Caulfield AJ, Walker ME, Gielda LM, Lathem WW. The Pla protease of Yersinia pestis degrades fas ligand to manipulate host cell death and inflammation. Cell Host & Microbe. 15: 424-34. PMID 24721571 DOI: 10.1016/J.Chom.2014.03.005  0.403
2014 Schiano CA, Koo JT, Schipma MJ, Caulfield AJ, Jafari N, Lathem WW. Genome-wide analysis of small RNAs expressed by Yersinia pestis identifies a regulator of the Yop-Ysc type III secretion system. Journal of Bacteriology. 196: 1659-70. PMID 24532772 DOI: 10.1128/Jb.01456-13  0.395
2014 Lathem WW, Schroeder JA, Bellows LE, Ritzert JT, Koo JT, Price PA, Caulfield AJ, Goldman WE. Posttranscriptional regulation of the Yersinia pestis cyclic AMP receptor protein Crp and impact on virulence. Mbio. 5: e01038-13. PMID 24520064 DOI: 10.1128/Mbio.01038-13  0.393
2013 Houppert AS, Bohman L, Merritt PM, Cole CB, Caulfield AJ, Lathem WW, Marketon MM. RfaL is required for Yersinia pestis type III secretion and virulence. Infection and Immunity. 81: 1186-97. PMID 23357388 DOI: 10.1128/Iai.01417-12  0.401
2012 Schiano CA, Lathem WW. Post-transcriptional regulation of gene expression in Yersinia species. Frontiers in Cellular and Infection Microbiology. 2: 129. PMID 23162797 DOI: 10.3389/Fcimb.2012.00129  0.373
2012 Bellows LE, Koestler BJ, Karaba SM, Waters CM, Lathem WW. Hfq-dependent, co-ordinate control of cyclic diguanylate synthesis and catabolism in the plague pathogen Yersinia pestis. Molecular Microbiology. 86: 661-74. PMID 22924957 DOI: 10.1111/Mmi.12011  0.399
2012 Koo JT, Lathem WW. Global discovery of small noncoding RNAs in pathogenic Yersinia species. Advances in Experimental Medicine and Biology. 954: 305-14. PMID 22782777 DOI: 10.1007/978-1-4614-3561-7_38  0.386
2012 Caulfield AJ, Lathem WW. Substrates of the plasminogen activator protease of Yersinia pestis. Advances in Experimental Medicine and Biology. 954: 253-60. PMID 22782771 DOI: 10.1007/978-1-4614-3561-7_32  0.442
2011 Koo JT, Alleyne TM, Schiano CA, Jafari N, Lathem WW. Global discovery of small RNAs in Yersinia pseudotuberculosis identifies Yersinia-specific small, noncoding RNAs required for virulence. Proceedings of the National Academy of Sciences of the United States of America. 108: E709-17. PMID 21876162 DOI: 10.1073/Pnas.1101655108  0.375
2010 Schiano CA, Bellows LE, Lathem WW. The small RNA chaperone Hfq is required for the virulence of Yersinia pseudotuberculosis. Infection and Immunity. 78: 2034-44. PMID 20231416 DOI: 10.1128/Iai.01046-09  0.435
2007 Lathem WW, Price PA, Miller VL, Goldman WE. A plasminogen-activating protease specifically controls the development of primary pneumonic plague. Science (New York, N.Y.). 315: 509-13. PMID 17255510 DOI: 10.1126/Science.1137195  0.336
2006 Cathelyn JS, Crosby SD, Lathem WW, Goldman WE, Miller VL. RovA, a global regulator of Yersinia pestis, specifically required for bubonic plague. Proceedings of the National Academy of Sciences of the United States of America. 103: 13514-9. PMID 16938880 DOI: 10.1073/Pnas.0603456103  0.422
2005 Lathem WW, Crosby SD, Miller VL, Goldman WE. Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 17786-91. PMID 16306265 DOI: 10.1073/Pnas.0506840102  0.393
2005 Grys TE, Siegel MB, Lathem WW, Welch RA. The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells. Infection and Immunity. 73: 1295-303. PMID 15731026 DOI: 10.1128/Iai.73.3.1295-1303.2005  0.665
2004 Lathem WW, Bergsbaken T, Welch RA. Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by Escherichia coli O157:H7. The Journal of Experimental Medicine. 199: 1077-87. PMID 15096536 DOI: 10.1084/Jem.20030255  0.654
2003 Lathem WW, Bergsbaken T, Witowski SE, Perna NT, Welch RA. Acquisition of stcE, a C1 esterase inhibitor-specific metalloprotease, during the evolution of Escherichia coli O157:H7. The Journal of Infectious Diseases. 187: 1907-14. PMID 12792867 DOI: 10.1086/374719  0.669
2002 Lathem WW, Grys TE, Witowski SE, Torres AG, Kaper JB, Tarr PI, Welch RA. StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor. Molecular Microbiology. 45: 277-88. PMID 12123444 DOI: 10.1046/J.1365-2958.2002.02997.X  0.669
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