| Year |
Citation |
Score |
| 2023 |
Miao X, Shen S, Koch G, Wang X, Li J, Shen X, Qu J, Straubinger RM, Jusko WJ. Systems pharmacodynamic model of combined gemcitabine and trabectedin in pancreatic cancer cells. Part I.Çô Effects on signal transduction pathways related to tumor growth. Journal of Pharmaceutical Sciences. 113: 214-227. PMID 38498417 DOI: 10.1016/j.xphs.2023.10.030 |
0.582 |
|
| 2023 |
Miao X, Koch G, Shen S, Wang X, Li J, Shen X, Qu J, Straubinger RM, Jusko WJ. Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways. Journal of Pharmaceutical Sciences. PMID 37918792 DOI: 10.1016/j.xphs.2023.10.036 |
0.59 |
|
| 2022 |
Lin Q, Shen S, Qian Z, Rasam SS, Serratore A, Jusko WJ, Kandel ES, Qu J, Straubinger RM. Comparative proteomic analysis identifies key metabolic regulators of gemcitabine resistance in pancreatic cancer. Molecular & Cellular Proteomics : McP. 100409. PMID 36084875 DOI: 10.1016/j.mcpro.2022.100409 |
0.552 |
|
| 2022 |
Ren T, Zhu X, Jusko NM, Krzyzanski W, Jusko WJ. Pharmacodynamic model of slow reversible binding and its applications in pharmacokinetic/pharmacodynamic modeling: review and tutorial. Journal of Pharmacokinetics and Pharmacodynamics. PMID 36040645 DOI: 10.1007/s10928-022-09822-y |
0.524 |
|
| 2021 |
Pawaskar D, Chen X, Glassman F, May F, Roberts A, Biondo M, McKenzie A, Nolte MW, Jusko WJ, Tortorici M. Pharmacokinetic/pharmacodynamic modeling for dose selection for the first-in-human trial of the activated Factor XII inhibitor garadacimab (CSL312). Clinical and Translational Science. PMID 34811931 DOI: 10.1111/cts.13192 |
0.792 |
|
| 2021 |
Krzyzanski W, Milad MA, Jobe AH, Peppard T, Bies RR, Jusko WJ. Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women. Journal of Pharmacokinetics and Pharmacodynamics. PMID 33954911 DOI: 10.1007/s10928-021-09755-y |
0.307 |
|
| 2021 |
Lin Q, Qian Z, Jusko WJ, Mager DE, Ma WW, Straubinger RM. Synergistic pharmacodynamic effects of gemcitabine and fibroblast growth factor receptor inhibitors on pancreatic cancer cell cycle kinetics and proliferation. The Journal of Pharmacology and Experimental Therapeutics. PMID 33753538 DOI: 10.1124/jpet.120.000412 |
0.692 |
|
| 2020 |
Li X, DuBois DC, Almon RR, Jusko WJ. . The Journal of Pharmacology and Experimental Therapeutics. PMID 32883831 DOI: 10.1124/Jpet.120.000191 |
0.363 |
|
| 2020 |
Acevedo A, DuBois D, Almon RR, Jusko WJ, Androulakis IP. Modeling Pathway Dynamics of the Skeletal Muscle Response to Intravenous Methylprednisolone (MPL) Administration in Rats: Dosing and Tissue Effects. Frontiers in Bioengineering and Biotechnology. 8: 759. PMID 32760706 DOI: 10.3389/Fbioe.2020.00759 |
0.374 |
|
| 2020 |
Jusko WJ, Molins EAG, Ayyar VS. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32759367 DOI: 10.1124/Dmd.120.000118 |
0.764 |
|
| 2020 |
Song D, Sun L, DuBois DC, Almon RR, Meng S, Jusko WJ. Physiologically-Based Pharmacokinetics of Dexamethasone in Rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32601175 DOI: 10.1124/Dmd.120.091017 |
0.377 |
|
| 2020 |
Li X, Conklin LS, van den Anker J, Hoffman EP, Clemens PR, Jusko WJ. Exposure-Response Analysis of Vamorolone (VBP15) in Boys With Duchenne Muscular Dystrophy. Journal of Clinical Pharmacology. PMID 32434278 DOI: 10.1002/Jcph.1632 |
0.371 |
|
| 2020 |
Ayyar VS, Jusko WJ. Transitioning from Basic toward Systems Pharmacodynamic Models: Lessons from Corticosteroids. Pharmacological Reviews. 72: 414-438. PMID 32123034 DOI: 10.1124/Pr.119.018101 |
0.783 |
|
| 2019 |
Jobe AH, Milad MA, Peppard T, Jusko WJ. Pharmacokinetics and Pharmacodynamics of intramuscular and oral betamethasone and dexamethasone in reproductive age women in India. Clinical and Translational Science. PMID 31808984 DOI: 10.1111/Cts.12724 |
0.359 |
|
| 2019 |
Yu R, Song D, DuBois DC, Almon RR, Jusko WJ. Modeling Combined Anti-Inflammatory Effects of Dexamethasone and Tofacitinib in Arthritic Rats. The Aaps Journal. 21: 93. PMID 31342216 DOI: 10.1208/S12248-019-0362-6 |
0.406 |
|
| 2019 |
Ayyar VS, Song D, DuBois DC, Almon RR, Jusko WJ. Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics - I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat. The Journal of Pharmacology and Experimental Therapeutics. PMID 31197020 DOI: 10.1124/Jpet.119.257519 |
0.77 |
|
| 2019 |
Ayyar VS, DuBois DC, Nakamura T, Almon RR, Jusko WJ. Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics - II: Sex Differences in Methylprednisolone Pharmacokinetics and Corticosterone Suppression. The Journal of Pharmacology and Experimental Therapeutics. PMID 31197019 DOI: 10.1124/Jpet.119.257527 |
0.775 |
|
| 2019 |
Ayyar VS, DuBois DC, Almon RR, Jusko WJ. Modeling Corticosteroid Pharmacokinetics & Pharmacodynamics - III: Estrous Cycle- and Estrogen Receptor-Dependent Antagonism of GILZ Enhancement by Corticosteroids. The Journal of Pharmacology and Experimental Therapeutics. PMID 31197018 DOI: 10.1124/Jpet.119.257543 |
0.773 |
|
| 2019 |
Mavroudis PD, Ayyar VS, Jusko WJ. ATLAS mPBPK: a MATLAb-based tool for modeling and Simulation of minimal Physiologically Based PharmacoKinetic models. Cpt: Pharmacometrics & Systems Pharmacology. PMID 31154668 DOI: 10.1002/psp4.12441 |
0.75 |
|
| 2019 |
Acevedo A, Berthel A, DuBois D, Almon RR, Jusko WJ, Androulakis IP. Pathway-Based Analysis of the Liver Response to Intravenous Methylprednisolone Administration in Rats: Acute Versus Chronic Dosing. Gene Regulation and Systems Biology. 13: 1177625019840282. PMID 31019365 DOI: 10.1177/1177625019840282 |
0.363 |
|
| 2019 |
Mavroudis PD, van den Anker J, Conklin LS, Damsker JM, Hoffman EP, Nagaraju K, Clemens PR, Jusko WJ. Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys With Duchenne Muscular Dystrophy. Journal of Clinical Pharmacology. PMID 30742306 DOI: 10.1002/Jcph.1388 |
0.384 |
|
| 2019 |
Ayyar VS, Krzyzanski W, Jusko WJ. Indirect pharmacodynamic models for responses with circadian removal. Journal of Pharmacokinetics and Pharmacodynamics. 46: 89-101. PMID 30694437 DOI: 10.1007/S10928-019-09620-Z |
0.766 |
|
| 2019 |
Luo D, Carter KA, Molins EAG, Straubinger NL, Geng J, Shao S, Jusko WJ, Straubinger RM, Lovell JF. Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30684512 DOI: 10.1016/J.Jconrel.2019.01.030 |
0.628 |
|
| 2019 |
Jusko WJ, Gobburu JV. Role of dosage regimen in controlling indirect pharmacodynamic responses. Advanced Drug Delivery Reviews. 33: 221-233. PMID 10837662 DOI: 10.1016/S0169-409X(98)00030-1 |
0.356 |
|
| 2018 |
Conklin LS, Damsker JM, Hoffman EP, Jusko WJ, Mavroudis PD, Schwartz BD, Mengle-Gaw LJ, Smith EC, Mah JK, Guglieri M, Nevo Y, Kuntz N, McDonald CM, Tulinius M, Ryan MM, et al. Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug. Pharmacological Research. PMID 30219580 DOI: 10.1016/J.Phrs.2018.09.007 |
0.348 |
|
| 2018 |
Ayyar VS, Sukumaran S, DuBois DC, Almon RR, Jusko WJ. Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver. The Journal of Pharmacology and Experimental Therapeutics. PMID 30087156 DOI: 10.1124/Jpet.118.251959 |
0.75 |
|
| 2018 |
Zhu X, Shen X, Qu J, Straubinger RM, Jusko WJ. Multi-Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells. Cpt: Pharmacometrics & Systems Pharmacology. PMID 30084546 DOI: 10.1002/psp4.12320 |
0.655 |
|
| 2018 |
Zhu X, Trueman S, Straubinger RM, Jusko WJ. Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts. Journal of Pharmacokinetics and Pharmacodynamics. PMID 30069744 DOI: 10.1007/S10928-018-9603-Z |
0.71 |
|
| 2018 |
Molins EAG, Jusko WJ. Assessment of Three-Drug Combination Pharmacodynamic Interactions in Pancreatic Cancer Cells. The Aaps Journal. 20: 80. PMID 29951754 DOI: 10.1208/S12248-018-0235-4 |
0.31 |
|
| 2018 |
Ayyar VS, Sukumaran S, DuBois DC, Almon RR, Qu J, Jusko WJ. Receptor/gene/protein-mediated signaling connects methylprednisolone exposure to metabolic and immune-related pharmacodynamic actions in liver. Journal of Pharmacokinetics and Pharmacodynamics. PMID 29704219 DOI: 10.1007/S10928-018-9585-X |
0.772 |
|
| 2018 |
Zhu X, Shen X, Qu J, Straubinger RM, Jusko WJ. Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells. Frontiers in Pharmacology. 9: 84. PMID 29520231 DOI: 10.3389/Fphar.2018.00084 |
0.679 |
|
| 2018 |
Chen X, Jiang X, Doddareddy RJRD, Geist B, McIntosh T, Jusko WJ, Zhou H, Wang W. Development and translational application of a minimal physiologically-based pharmacokinetic (mPBPK) model for a monoclonal antibody (mAb) against interleukin 23 (IL-23) in IL-23-induced psoriasis-like (PsL) mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 29420255 DOI: 10.1124/Jpet.117.244855 |
0.366 |
|
| 2017 |
McLaughlin MJ, He Y, Brunstrom-Hernandez J, Thio LL, Carleton BC, Ross CJD, Gaedigk A, Lewandowski A, Dai H, Jusko WJ, Leeder JS. Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children with Cerebral Palsy. Pm & R : the Journal of Injury, Function, and Rehabilitation. PMID 28867665 DOI: 10.1016/J.Pmrj.2017.08.441 |
0.403 |
|
| 2017 |
Ayyar VS, DuBois DC, Almon RR, Jusko WJ. Mechanistic Multi-Tissue Modeling of GILZ Regulation: Integrating Circadian Gene Expression with Receptor-Mediated Corticosteroid Pharmacodynamics. The Journal of Pharmacology and Experimental Therapeutics. PMID 28729456 DOI: 10.1124/Jpet.117.242990 |
0.778 |
|
| 2017 |
Li X, DuBois DC, Song D, Almon RR, Jusko WJ, Chen X. Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28416614 DOI: 10.1124/Dmd.117.075614 |
0.387 |
|
| 2017 |
Chen X, DuBois DC, Almon RR, Jusko WJ. Interrelationships between Infliximab and rhTNF-α in Plasma using Minimal Physiologically-Based Pharmacokinetic (mPBPK) Models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28411280 DOI: 10.1124/Dmd.116.074807 |
0.32 |
|
| 2017 |
Chen X, DuBois DC, Almon RR, Jusko WJ. Characterization and Interspecies Scaling of rhTNF-α Pharmacokinetics with Minimal Physiologically-Based Pharmacokinetic (mPBPK) Models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28411279 DOI: 10.1124/Dmd.116.074799 |
0.401 |
|
| 2017 |
Ayyar VS, Almon RR, DuBois DC, Sukumaran S, Qu J, Jusko WJ. Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism. Journal of Proteomics. PMID 28315483 DOI: 10.1016/J.Jprot.2017.03.007 |
0.756 |
|
| 2017 |
Li X, DuBois DC, Almon RR, Jusko WJ. Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28246127 DOI: 10.1124/Dmd.116.074526 |
0.415 |
|
| 2017 |
Li X, DuBois DC, Almon RR, Jusko WJ. Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28246126 DOI: 10.1124/Dmd.116.074500 |
0.389 |
|
| 2017 |
Koch G, Jusko WJ, Schropp J. Target mediated drug disposition with drug-drug interaction, Part II: competitive and uncompetitive cases. Journal of Pharmacokinetics and Pharmacodynamics. PMID 28074396 DOI: 10.1007/S10928-016-9502-0 |
0.357 |
|
| 2017 |
Koch G, Jusko WJ, Schropp J. Target-mediated drug disposition with drug-drug interaction, Part I: single drug case in alternative formulations. Journal of Pharmacokinetics and Pharmacodynamics. PMID 28074395 DOI: 10.1007/S10928-016-9501-1 |
0.356 |
|
| 2016 |
Miao X, Koch G, Ait-Oudhia S, Straubinger RM, Jusko WJ. Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells. Frontiers in Pharmacology. 7: 421. PMID 27895579 DOI: 10.3389/Fphar.2016.00421 |
0.732 |
|
| 2016 |
Koch G, Schropp J, Jusko WJ. Assessment of non-linear combination effect terms for drug-drug interactions. Journal of Pharmacokinetics and Pharmacodynamics. PMID 27638639 DOI: 10.1007/S10928-016-9490-0 |
0.373 |
|
| 2016 |
Jusko WJ. Clarification of contraceptive drug pharmacokinetics in obesity. Contraception. PMID 27542520 DOI: 10.1016/J.Contraception.2016.08.003 |
0.343 |
|
| 2016 |
Jusko WJ. Perspectives on variability in pharmacokinetics of an oral contraceptive product. Contraception. PMID 27475034 DOI: 10.1016/J.Contraception.2016.07.019 |
0.37 |
|
| 2016 |
Rao RT, DuBois DC, Almon RR, Jusko WJ, Androulakis IP. Mathematical Modeling of the Circadian Dynamics of the Neuroendocrine-Immune Network in Experimentally Induced Arthritis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00006.2016. PMID 27221115 DOI: 10.1152/Ajpendo.00006.2016 |
0.314 |
|
| 2016 |
Chen X, Jiang X, Jusko WJ, Zhou H, Wang W. Minimal physiologically-based pharmacokinetic (mPBPK) model for a monoclonal antibody against interleukin-6 in mice with collagen-induced arthritis. Journal of Pharmacokinetics and Pharmacodynamics. PMID 27119518 DOI: 10.1007/S10928-016-9472-2 |
0.353 |
|
| 2015 |
Miao X, Koch G, Straubinger RM, Jusko WJ. Pharmacodynamic modeling of combined chemotherapeutic effects predicts synergistic activity of gemcitabine and trabectedin in pancreatic cancer cells. Cancer Chemotherapy and Pharmacology. PMID 26604207 DOI: 10.1007/S00280-015-2907-4 |
0.723 |
|
| 2015 |
Lon HK, DuBois DC, Earp JC, Almon RR, Jusko WJ. Modeling effects of dexamethasone on disease progression of bone mineral density in collagen-induced arthritic rats. Pharmacology Research & Perspectives. 3: e00169. PMID 26516581 DOI: 10.1002/Prp2.169 |
0.776 |
|
| 2015 |
Jusko WJ, Fung HL. Preface to the special issue to honor Gerhard Levy and 50 years of PK/PD. Journal of Pharmacokinetics and Pharmacodynamics. 42: 427. PMID 26403701 DOI: 10.1007/S10928-015-9443-Z |
0.322 |
|
| 2015 |
Zhu X, Straubinger RM, Jusko WJ. Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells. Journal of Pharmacokinetics and Pharmacodynamics. 42: 477-96. PMID 26252969 DOI: 10.1007/S10928-015-9429-X |
0.702 |
|
| 2015 |
Yoo H, Iirola T, Vilo S, Manner T, Aantaa R, Lahtinen M, Scheinin M, Olkkola KT, Jusko WJ. Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects. European Journal of Clinical Pharmacology. 71: 1197-207. PMID 26233335 DOI: 10.1007/S00228-015-1913-0 |
0.3 |
|
| 2015 |
Ayyar VS, Almon RR, Jusko WJ, DuBois DC. Quantitative tissue-specific dynamics of in vivo GILZ mRNA expression and regulation by endogenous and exogenous glucocorticoids. Physiological Reports. 3. PMID 26056061 DOI: 10.14814/Phy2.12382 |
0.756 |
|
| 2015 |
Chen X, DuBois DC, Almon RR, Jusko WJ. Biodistribution of etanercept to tissues and sites of inflammation in arthritic rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 898-907. PMID 25834031 DOI: 10.1124/Dmd.114.062901 |
0.38 |
|
| 2015 |
Kamisoglu K, Sukumaran S, Nouri-Nigjeh E, Tu C, Li J, Shen X, Duan X, Qu J, Almon RR, DuBois DC, Jusko WJ, Androulakis IP. Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics. Omics : a Journal of Integrative Biology. 19: 80-91. PMID 25611119 DOI: 10.1089/Omi.2014.0130 |
0.31 |
|
| 2015 |
Grimsrud KN, Ait-Oudhia S, Durbin-Johnson BP, Rocke DM, Mama KR, Rezende ML, Stanley SD, Jusko WJ. Pharmacokinetic and pharmacodynamic analysis comparing diverse effects of detomidine, medetomidine, and dexmedetomidine in the horse: a population analysis. Journal of Veterinary Pharmacology and Therapeutics. 38: 24-34. PMID 25073816 DOI: 10.1111/Jvp.12139 |
0.402 |
|
| 2014 |
Wang X, DuBois DC, Sukumaran S, Ayyar V, Jusko WJ, Almon RR. Variability in Zucker diabetic fatty rats: differences in disease progression in hyperglycemic and normoglycemic animals. Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy. 7: 531-41. PMID 25419150 DOI: 10.2147/Dmso.S69891 |
0.753 |
|
| 2014 |
Cao Y, Jusko WJ. Survey of monoclonal antibody disposition in man utilizing a minimal physiologically-based pharmacokinetic model. Journal of Pharmacokinetics and Pharmacodynamics. 41: 571-80. PMID 25146360 DOI: 10.1007/S10928-014-9374-0 |
0.362 |
|
| 2014 |
Wang X, DuBois DC, Cao Y, Jusko WJ, Almon RR. Diabetes disease progression in Goto-Kakizaki rats: effects of salsalate treatment. Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy. 7: 381-9. PMID 25120374 DOI: 10.2147/Dmso.S65818 |
0.312 |
|
| 2014 |
Cao Y, Jusko WJ. Incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies. Journal of Pharmacokinetics and Pharmacodynamics. 41: 375-87. PMID 25077917 DOI: 10.1007/S10928-014-9372-2 |
0.389 |
|
| 2014 |
Nouri-Nigjeh E, Sukumaran S, Tu C, Li J, Shen X, Duan X, DuBois DC, Almon RR, Jusko WJ, Qu J. Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by methylprednisolone in 60 rats. Analytical Chemistry. 86: 8149-57. PMID 25072516 DOI: 10.1021/Ac501380S |
0.351 |
|
| 2014 |
He Y, Brunstrom-Hernandez JE, Thio LL, Lackey S, Gaebler-Spira D, Kuroda MM, Stashinko E, Hoon AH, Vargus-Adams J, Stevenson RD, Lowenhaupt S, McLaughlin JF, Christensen A, Dosa NP, Butler M, ... ... Jusko WJ, et al. Population pharmacokinetics of oral baclofen in pediatric patients with cerebral palsy. The Journal of Pediatrics. 164: 1181-1188.e8. PMID 24607242 DOI: 10.1016/J.Jpeds.2014.01.029 |
0.501 |
|
| 2013 |
Fang J, Sukumaran S, Dubois DC, Almon RR, Jusko WJ. Meta-modeling of methylprednisolone effects on glucose regulation in rats. Plos One. 8: e81679. PMID 24312573 DOI: 10.1371/Journal.Pone.0081679 |
0.477 |
|
| 2013 |
Lon HK, Liu D, DuBois DC, Almon RR, Jusko WJ. Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach. Journal of Pharmacokinetics and Pharmacodynamics. 40: 701-12. PMID 24233383 DOI: 10.1007/S10928-013-9341-1 |
0.819 |
|
| 2013 |
Cao Y, Balthasar JP, Jusko WJ. Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies. Journal of Pharmacokinetics and Pharmacodynamics. 40: 597-607. PMID 23996115 DOI: 10.1007/S10928-013-9332-2 |
0.355 |
|
| 2013 |
Hamed SS, Straubinger RM, Jusko WJ. Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells. Cancer Chemotherapy and Pharmacology. 72: 553-63. PMID 23835677 DOI: 10.1007/S00280-013-2226-6 |
0.6 |
|
| 2013 |
Jusko WJ. Moving from basic toward systems pharmacodynamic models. Journal of Pharmaceutical Sciences. 102: 2930-40. PMID 23681608 DOI: 10.1002/Jps.23590 |
0.34 |
|
| 2013 |
Liu DY, Lon HK, Wang YL, DuBois DC, Almon RR, Jusko WJ. Pharmacokinetics, pharmacodynamics and toxicities of methotrexate in healthy and collagen-induced arthritic rats. Biopharmaceutics & Drug Disposition. 34: 203-14. PMID 23456770 DOI: 10.1002/Bdd.1838 |
0.815 |
|
| 2013 |
Pawaskar DK, Straubinger RM, Fetterly GJ, Hylander BH, Repasky EA, Ma WW, Jusko WJ. Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice. Cancer Chemotherapy and Pharmacology. 71: 1231-40. PMID 23455452 DOI: 10.1007/S00280-013-2117-X |
0.8 |
|
| 2013 |
Pawaskar DK, Straubinger RM, Fetterly GJ, Hylander BH, Repasky EA, Ma WW, Jusko WJ. Physiologically based pharmacokinetic models for everolimus and sorafenib in mice. Cancer Chemotherapy and Pharmacology. 71: 1219-29. PMID 23455451 DOI: 10.1007/S00280-013-2116-Y |
0.804 |
|
| 2013 |
DuBois DC, Sukumaran S, Jusko WJ, Almon RR. Evidence for a glucocorticoid receptor beta splice variant in the rat and its physiological regulation in liver. Steroids. 78: 312-20. PMID 23257260 DOI: 10.1016/J.Steroids.2012.11.014 |
0.339 |
|
| 2013 |
Pawaskar DK, Straubinger RM, Fetterly GJ, Ma WW, Jusko WJ. Interactions of everolimus and sorafenib in whole blood lymphocyte proliferation. Pharmaceutical Research. 30: 707-13. PMID 23151723 DOI: 10.1007/S11095-012-0909-Z |
0.795 |
|
| 2013 |
Pawaskar DK, Straubinger RM, Fetterly GJ, Ma WW, Jusko WJ. Interactions of everolimus and sorafenib in pancreatic cancer cells. The Aaps Journal. 15: 78-84. PMID 23054975 DOI: 10.1208/S12248-012-9417-7 |
0.791 |
|
| 2013 |
Fang J, Landersdorfer CB, Cirincione B, Jusko WJ. Study reanalysis using a mechanism-based pharmacokinetic/pharmacodynamic model of pramlintide in subjects with type 1 diabetes. The Aaps Journal. 15: 15-29. PMID 23054970 DOI: 10.1208/S12248-012-9409-7 |
0.494 |
|
| 2012 |
Cao Y, Jusko WJ. Applications of minimal physiologically-based pharmacokinetic models. Journal of Pharmacokinetics and Pharmacodynamics. 39: 711-23. PMID 23179857 DOI: 10.1007/S10928-012-9280-2 |
0.388 |
|
| 2012 |
Lon HK, Liu D, Jusko WJ. Pharmacokinetic/pharmacodynamic modeling in inflammation. Critical Reviews in Biomedical Engineering. 40: 295-312. PMID 23140121 DOI: 10.1615/Critrevbiomedeng.V40.I4.50 |
0.808 |
|
| 2012 |
Cao Y, DuBois DC, Almon RR, Jusko WJ. Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats. Biopharmaceutics & Drug Disposition. 33: 285-91. PMID 22782506 DOI: 10.1002/Bdd.1797 |
0.339 |
|
| 2012 |
Jusko WJ. Use of pharmacokinetic data below lower limit of quantitation values. Pharmaceutical Research. 29: 2628-31. PMID 22729370 DOI: 10.1007/S11095-012-0805-6 |
0.383 |
|
| 2012 |
Landersdorfer CB, He YL, Jusko WJ. Mechanism-based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV. British Journal of Clinical Pharmacology. 73: 391-401. PMID 22442826 DOI: 10.1111/J.1365-2125.2011.04108.X |
0.411 |
|
| 2012 |
Sukumaran S, Lepist EI, DuBois DC, Almon RR, Jusko WJ. Pharmacokinetic/pharmacodynamic modeling of methylprednisolone effects on iNOS mRNA expression and nitric oxide during LPS-induced inflammation in rats. Pharmaceutical Research. 29: 2060-9. PMID 22422321 DOI: 10.1007/S11095-012-0733-5 |
0.365 |
|
| 2012 |
Gao W, Jusko WJ. Modeling disease progression and rosiglitazone intervention in type 2 diabetic Goto-Kakizaki rats. The Journal of Pharmacology and Experimental Therapeutics. 341: 617-25. PMID 22378938 DOI: 10.1124/Jpet.112.192419 |
0.382 |
|
| 2012 |
Gao W, Jusko WJ. Target-mediated pharmacokinetic and pharmacodynamic model of exendin-4 in rats, monkeys, and humans. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 990-7. PMID 22338110 DOI: 10.1124/Dmd.111.042291 |
0.502 |
|
| 2012 |
Cao Y, Gao W, Jusko WJ. Pharmacokinetic/pharmacodynamic modeling of GLP-1 in healthy rats. Pharmaceutical Research. 29: 1078-86. PMID 22179928 DOI: 10.1007/S11095-011-0652-X |
0.446 |
|
| 2012 |
Chaudhuri TR, Straubinger NL, Pitoniak R, Hylander BL, Jusko WJ, Ma WW, Straubinger RM. Abstract 5685: Effects of sonic Hedgehog inhibitor combined with nanoparticulate drug delivery on vascular permeability and efficacy in a pancreatic cancer model Cancer Research. 72: 5685-5685. DOI: 10.1158/1538-7445.Am2012-5685 |
0.611 |
|
| 2012 |
Pawaskar DK, Straubinger RM, Fetterly G, Hylander BH, Repasky EA, Ma WW, Jusko WJ. Abstract 3681: Multi-scale analysis of everolimus and sorafenib combination in pancreatic cancer xenografts Cancer Research. 72: 3681-3681. DOI: 10.1158/1538-7445.Am2012-3681 |
0.819 |
|
| 2012 |
Ma W, Weekes C, Pawaskar D, Fetterly G, Messersmith W, Dy G, Straubinger R, Jusko W, Eckhardt S, Adjei A. 584 Preclinical and Clinical Evaluation of the Combination of Sorafenib and Everolimus in Patients with Advanced Solid Tumors European Journal of Cancer. 48: 179. DOI: 10.1016/S0923-7534(20)33076-3 |
0.794 |
|
| 2011 |
Liu D, Lon HK, Dubois DC, Almon RR, Jusko WJ. Population pharmacokinetic-pharmacodynamic-disease progression model for effects of anakinra in Lewis rats with collagen-induced arthritis. Journal of Pharmacokinetics and Pharmacodynamics. 38: 769-86. PMID 22002845 DOI: 10.1007/S10928-011-9219-Z |
0.816 |
|
| 2011 |
Møller JB, Jusko WJ, Gao W, Hansen T, Pedersen O, Holst JJ, Overgaard RV, Madsen H, Ingwersen SH. Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test. Journal of Pharmacokinetics and Pharmacodynamics. 38: 713-25. PMID 21922329 DOI: 10.1007/S10928-011-9216-2 |
0.398 |
|
| 2011 |
Cao Y, Dubois DC, Sun H, Almon RR, Jusko WJ. Modeling diabetes disease progression and salsalate intervention in Goto-Kakizaki rats. The Journal of Pharmacology and Experimental Therapeutics. 339: 896-904. PMID 21903749 DOI: 10.1124/Jpet.111.185686 |
0.317 |
|
| 2011 |
Sukumaran S, Jusko WJ, DuBois DC, Almon RR. Mechanistic modeling of the effects of glucocorticoids and circadian rhythms on adipokine expression. The Journal of Pharmacology and Experimental Therapeutics. 337: 734-46. PMID 21398515 DOI: 10.1124/Jpet.111.179960 |
0.326 |
|
| 2011 |
Fang J, DuBois DC, He Y, Almon RR, Jusko WJ. Dynamic modeling of methylprednisolone effects on body weight and glucose regulation in rats. Journal of Pharmacokinetics and Pharmacodynamics. 38: 293-316. PMID 21394487 DOI: 10.1007/S10928-011-9194-4 |
0.547 |
|
| 2011 |
Lon HK, Liu D, Zhang Q, DuBois DC, Almon RR, Jusko WJ. Pharmacokinetic-pharmacodynamic disease progression model for effect of etanercept in Lewis rats with collagen-induced arthritis. Pharmaceutical Research. 28: 1622-30. PMID 21360252 DOI: 10.1007/S11095-011-0396-7 |
0.807 |
|
| 2011 |
Scheff JD, Almon RR, Dubois DC, Jusko WJ, Androulakis IP. Assessment of pharmacologic area under the curve when baselines are variable. Pharmaceutical Research. 28: 1081-9. PMID 21234658 DOI: 10.1007/S11095-010-0363-8 |
0.314 |
|
| 2011 |
Nie J, DuBois DC, Jusko WJ, Almon RR. Mechanistic population modeling of diabetes disease progression in Goto-Kakizaki rat muscle. Biopharmaceutics & Drug Disposition. 32: 50-63. PMID 21162119 DOI: 10.1002/Bdd.738 |
0.316 |
|
| 2011 |
Gao W, Jusko WJ. Pharmacokinetic and pharmacodynamic modeling of exendin-4 in type 2 diabetic Goto-Kakizaki rats. The Journal of Pharmacology and Experimental Therapeutics. 336: 881-90. PMID 21156817 DOI: 10.1124/Jpet.110.175752 |
0.424 |
|
| 2011 |
Gao W, Bihorel S, DuBois DC, Almon RR, Jusko WJ. Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats. Journal of Pharmacokinetics and Pharmacodynamics. 38: 143-62. PMID 21127951 DOI: 10.1007/S10928-010-9182-0 |
0.392 |
|
| 2011 |
Pawaskar DK, Straubinger R, Fetterly G, Ma W, Jusko W. Abstract 27: Physiologically based pharmacokinetic model for interactions of sorafenib and everolimus in mice Cancer Research. 71: 27-27. DOI: 10.1158/1538-7445.Am2011-27 |
0.818 |
|
| 2010 |
Nguyen TT, Almon RR, Dubois DC, Jusko WJ, Androulakis IP. Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: transcriptional dynamics and regulatory structures. Bmc Bioinformatics. 11: 515. PMID 20946642 DOI: 10.1186/1471-2105-11-515 |
0.327 |
|
| 2010 |
Sukumaran S, Almon RR, DuBois DC, Jusko WJ. Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action. Advanced Drug Delivery Reviews. 62: 904-17. PMID 20542067 DOI: 10.1016/J.Addr.2010.05.009 |
0.333 |
|
| 2010 |
Findling RL, Landersdorfer CB, Kafantaris V, Pavuluri M, McNamara NK, McClellan J, Frazier JA, Sikich L, Kowatch R, Lingler J, Faber J, Taylor-Zapata P, Jusko WJ. First-dose pharmacokinetics of lithium carbonate in children and adolescents. Journal of Clinical Psychopharmacology. 30: 404-10. PMID 20531219 DOI: 10.1097/Jcp.0B013E3181E66A62 |
0.356 |
|
| 2010 |
Nguyen TT, Almon RR, DuBois DC, Jusko WJ, Androulakis IP. Importance of replication in analyzing time-series gene expression data: corticosteroid dynamics and circadian patterns in rat liver. Bmc Bioinformatics. 11: 279. PMID 20500897 DOI: 10.1186/1471-2105-11-279 |
0.304 |
|
| 2010 |
Bulitta JB, Yang JC, Yohonn L, Ly NS, Brown SV, D'Hondt RE, Jusko WJ, Forrest A, Tsuji BT. Attenuation of colistin bactericidal activity by high inoculum of Pseudomonas aeruginosa characterized by a new mechanism-based population pharmacodynamic model. Antimicrobial Agents and Chemotherapy. 54: 2051-62. PMID 20211900 DOI: 10.1128/Aac.00881-09 |
0.754 |
|
| 2010 |
Ghoshal S, Rao I, Earp JC, Jusko WJ, Wetzler M. Down-regulation of heat shock protein 70 improves arsenic trioxide and 17-DMAG effects on constitutive signal transducer and activator of transcription 3 activity. Cancer Chemotherapy and Pharmacology. 66: 681-9. PMID 20035426 DOI: 10.1007/S00280-009-1210-7 |
0.677 |
|
| 2009 |
Khinkis LA, Krzyzanski W, Jusko WJ, Greco WR. D-optimal designs for parameter estimation for indirect pharmacodynamic response models. Journal of Pharmacokinetics and Pharmacodynamics. 36: 523-39. PMID 19904585 DOI: 10.1007/S10928-009-9135-7 |
0.335 |
|
| 2009 |
Woo S, Pawaskar D, Jusko WJ. Methods of utilizing baseline values for indirect response models. Journal of Pharmacokinetics and Pharmacodynamics. 36: 381-405. PMID 19697107 DOI: 10.1007/S10928-009-9128-6 |
0.772 |
|
| 2009 |
Cho HY, Blum RA, Sunderland T, Cooper GJ, Jusko WJ. Pharmacokinetic and pharmacodynamic modeling of a copper-selective chelator (TETA) in healthy adults. Journal of Clinical Pharmacology. 49: 916-28. PMID 19602718 DOI: 10.1177/0091270009337939 |
0.415 |
|
| 2009 |
Mager DE, Woo S, Jusko WJ. Scaling pharmacodynamics from in vitro and preclinical animal studies to humans. Drug Metabolism and Pharmacokinetics. 24: 16-24. PMID 19252333 DOI: 10.2133/Dmpk.24.16 |
0.69 |
|
| 2009 |
Jin JY, Jusko WJ. Pharmacodynamics of glucose regulation by methylprednisolone. I. Adrenalectomized rats. Biopharmaceutics & Drug Disposition. 30: 21-34. PMID 19156931 DOI: 10.1002/Bdd.643 |
0.501 |
|
| 2009 |
Jin JY, Jusko WJ. Pharmacodynamics of glucose regulation by methylprednisolone. II. normal rats. Biopharmaceutics & Drug Disposition. 30: 35-48. PMID 19156669 DOI: 10.1002/Bdd.642 |
0.515 |
|
| 2009 |
Almon RR, DuBois DC, Lai W, Xue B, Nie J, Jusko WJ. Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats. The Journal of Endocrinology. 200: 331-46. PMID 19074471 DOI: 10.1677/Joe-08-0404 |
0.301 |
|
| 2009 |
Landersdorfer CB, DuBois DC, Almon RR, Jusko WJ. Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats. The Journal of Pharmacology and Experimental Therapeutics. 328: 644-51. PMID 18971370 DOI: 10.1124/Jpet.108.144766 |
0.304 |
|
| 2009 |
Bulitta JB, Ly NS, Yang JC, Forrest A, Jusko WJ, Tsuji BT. Development and qualification of a pharmacodynamic model for the pronounced inoculum effect of ceftazidime against Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 53: 46-56. PMID 18852268 DOI: 10.1128/Aac.00489-08 |
0.763 |
|
| 2009 |
Bulitta JB, Zhao P, Arnold RD, Kessler DR, Daifuku R, Pratt J, Luciano G, Hanauske AR, Gelderblom H, Awada A, Jusko WJ. Mechanistic population pharmacokinetics of total and unbound paclitaxel for a new nanodroplet formulation versus Taxol in cancer patients. Cancer Chemotherapy and Pharmacology. 63: 1049-63. PMID 18791718 DOI: 10.1007/S00280-008-0827-2 |
0.313 |
|
| 2009 |
Earp JC, Dubois DC, Almon RR, Jusko WJ. Quantitative dynamic models of arthritis progression in the rat. Pharmaceutical Research. 26: 196-203. PMID 18758921 DOI: 10.1007/S11095-008-9711-3 |
0.7 |
|
| 2008 |
Yao Z, Hoffman EP, Ghimbovschi S, DuBois DC, Almon RR, Jusko WJ. Pharmacodynamic/pharmacogenomic modeling of insulin resistance genes in rat muscle after methylprednisolone treatment: exploring regulatory signaling cascades. Gene Regulation and Systems Biology. 2: 141-61. PMID 19787081 DOI: 10.4137/Grsb.S613 |
0.535 |
|
| 2008 |
Hazra A, DuBois DC, Almon RR, Snyder GH, Jusko WJ. Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats. Gene Regulation and Systems Biology. 2: 1-19. PMID 19787073 DOI: 10.4137/Grsb.S0 |
0.351 |
|
| 2008 |
Rohatagi S, Carrothers TJ, Jin J, Jusko WJ, Khariton T, Walker J, Truitt K, Salazar DE. Model-based development of a PPARgamma agonist, rivoglitazone, to aid dose selection and optimize clinical trial designs. Journal of Clinical Pharmacology. 48: 1420-9. PMID 18936283 DOI: 10.1177/0091270008323260 |
0.37 |
|
| 2008 |
Earp JC, Pyszczynski NA, Molano DS, Jusko WJ. Pharmacokinetics of dexamethasone in a rat model of rheumatoid arthritis. Biopharmaceutics & Drug Disposition. 29: 366-72. PMID 18613033 DOI: 10.1002/Bdd.626 |
0.738 |
|
| 2008 |
Landersdorfer CB, Jusko WJ. Pharmacokinetic/pharmacodynamic modelling in diabetes mellitus. Clinical Pharmacokinetics. 47: 417-48. PMID 18563953 DOI: 10.2165/00003088-200847070-00001 |
0.338 |
|
| 2008 |
Almon RR, Yang E, Lai W, Androulakis IP, DuBois DC, Jusko WJ. Circadian variations in rat liver gene expression: relationships to drug actions. The Journal of Pharmacology and Experimental Therapeutics. 326: 700-16. PMID 18562560 DOI: 10.1124/Jpet.108.140186 |
0.318 |
|
| 2008 |
Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Keller CE, Almon RR, Jusko WJ. Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats. The Journal of Pharmacology and Experimental Therapeutics. 326: 532-45. PMID 18448865 DOI: 10.1124/Jpet.108.137372 |
0.701 |
|
| 2008 |
Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Almon RR, Jusko WJ. Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis. The Journal of Pharmacology and Experimental Therapeutics. 326: 546-54. PMID 18448864 DOI: 10.1124/Jpet.108.137414 |
0.724 |
|
| 2008 |
Mager DE, Jusko WJ. Development of translational pharmacokinetic-pharmacodynamic models. Clinical Pharmacology and Therapeutics. 83: 909-12. PMID 18388873 DOI: 10.1038/Clpt.2008.52 |
0.604 |
|
| 2008 |
Yao Z, Hoffman EP, Ghimbovschi S, Dubois DC, Almon RR, Jusko WJ. Mathematical modeling of corticosteroid pharmacogenomics in rat muscle following acute and chronic methylprednisolone dosing. Molecular Pharmaceutics. 5: 328-39. PMID 18271548 DOI: 10.1021/Mp700094S |
0.55 |
|
| 2008 |
Yang E, Almon RR, Dubois DC, Jusko WJ, Androulakis IP. Extracting global system dynamics of corticosteroid genomic effects in rat liver. The Journal of Pharmacology and Experimental Therapeutics. 324: 1243-54. PMID 18086872 DOI: 10.1124/Jpet.107.133074 |
0.336 |
|
| 2008 |
Woo S, Krzyzanski W, Duliege AM, Stead RB, Jusko WJ. Population pharmacokinetics and pharmacodynamics of peptidic erythropoiesis receptor agonist (ERA) in healthy volunteers. Journal of Clinical Pharmacology. 48: 43-52. PMID 18025524 DOI: 10.1177/0091270007309702 |
0.528 |
|
| 2008 |
Woo S, Krzyzanski W, Jusko WJ. Pharmacodynamic model for chemotherapy-induced anemia in rats. Cancer Chemotherapy and Pharmacology. 62: 123-33. PMID 17891399 DOI: 10.1007/S00280-007-0582-9 |
0.583 |
|
| 2008 |
Yao Z, DuBois DC, Almon RR, Jusko WJ. Pharmacokinetic/pharmacodynamic modeling of corticosterone suppression and lymphocytopenia by methylprednisolone in rats. Journal of Pharmaceutical Sciences. 97: 2820-32. PMID 17828751 DOI: 10.1002/Jps.21167 |
0.593 |
|
| 2008 |
Hazra A, Pyszczynski NA, DuBois DC, Almon RR, Jusko WJ. Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats. Pharmaceutical Research. 25: 769-80. PMID 17674160 DOI: 10.1007/S11095-007-9371-8 |
0.307 |
|
| 2007 |
Woo S, Krzyzanski W, Jusko WJ. Target-mediated pharmacokinetic and pharmacodynamic model of recombinant human erythropoietin (rHuEPO). Journal of Pharmacokinetics and Pharmacodynamics. 34: 849-68. PMID 17943422 DOI: 10.1007/S10928-007-9074-0 |
0.615 |
|
| 2007 |
Hazra A, Pyszczynski N, DuBois DC, Almon RR, Jusko WJ. Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids. Journal of Pharmacokinetics and Pharmacodynamics. 34: 643-67. PMID 17593325 DOI: 10.1007/S10928-007-9063-3 |
0.347 |
|
| 2007 |
Woo S, Jusko WJ. Interspecies comparisons of pharmacokinetics and pharmacodynamics of recombinant human erythropoietin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1672-8. PMID 17576810 DOI: 10.1124/Dmd.107.015248 |
0.567 |
|
| 2007 |
Hazra A, Pyszczynski N, DuBois DC, Almon RR, Jusko WJ. Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats. Biopharmaceutics & Drug Disposition. 28: 263-73. PMID 17569107 DOI: 10.1002/Bdd.551 |
0.367 |
|
| 2007 |
Almon RR, DuBois DC, Yao Z, Hoffman EP, Ghimbovschi S, Jusko WJ. Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens. Physiological Genomics. 30: 282-99. PMID 17473217 DOI: 10.1152/Physiolgenomics.00242.2006 |
0.566 |
|
| 2007 |
Wetzler M, Earp JC, Brady MT, Keng MK, Jusko WJ. Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2261-70. PMID 17404111 DOI: 10.1158/1078-0432.Ccr-06-2468 |
0.689 |
|
| 2007 |
Samtani MN, Jusko WJ. Quantification of dexamethasone and corticosterone in rat biofluids and fetal tissue using highly sensitive analytical methods: assay validation and application to a pharmacokinetic study. Biomedical Chromatography : Bmc. 21: 585-97. PMID 17385808 DOI: 10.1002/Bmc.788 |
0.674 |
|
| 2007 |
Hong Y, Mager DE, Blum RA, Jusko WJ. Population pharmacokinetic/pharmacodynamic modeling of systemic corticosteroid inhibition of whole blood lymphocytes: modeling interoccasion pharmacodynamic variability. Pharmaceutical Research. 24: 1088-97. PMID 17385022 DOI: 10.1007/S11095-006-9232-X |
0.629 |
|
| 2007 |
Yao Z, Zhao B, Hoffman EP, Ghimbovschi S, DuBois DC, Almon RR, Jusko WJ. Application of scaling factors in simultaneous modeling of microarray data from diverse chips. Pharmaceutical Research. 24: 643-9. PMID 17318415 DOI: 10.1007/S11095-006-9215-Y |
0.525 |
|
| 2007 |
Almon RR, DuBois DC, Jusko WJ. A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens. Endocrinology. 148: 2209-25. PMID 17303664 DOI: 10.1210/En.2006-0790 |
0.365 |
|
| 2007 |
Hazra A, DuBois DC, Almon RR, Jusko WJ. Assessing the dynamics of nuclear glucocorticoid-receptor complex: adding flexibility to gene expression modeling. Journal of Pharmacokinetics and Pharmacodynamics. 34: 333-54. PMID 17285360 DOI: 10.1007/S10928-007-9049-1 |
0.381 |
|
| 2006 |
Hazra A, Krzyzanski W, Jusko WJ. Mathematical assessment of properties of precursor-dependent indirect pharmacodynamic response models. Journal of Pharmacokinetics and Pharmacodynamics. 33: 683-717. PMID 17053985 DOI: 10.1007/S10928-006-9030-4 |
0.412 |
|
| 2006 |
Woo S, Krzyzanski W, Jusko WJ. Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 319: 1297-306. PMID 16973883 DOI: 10.1124/Jpet.106.111377 |
0.612 |
|
| 2006 |
Schwab M, Coksaygan T, Samtani MN, Jusko WJ, Nathanielsz PW. Kinetics of betamethasone and fetal cardiovascular adverse effects in pregnant sheep after different doses. Obstetrics and Gynecology. 108: 617-25. PMID 16946223 DOI: 10.1097/01.AOG.0000232815.80648.01 |
0.667 |
|
| 2006 |
Krzyzanski W, Dmochowski J, Matsushima N, Jusko WJ. Assessment of dosing impact on intra-individual variability in estimation of parameters for basic indirect response models. Journal of Pharmacokinetics and Pharmacodynamics. 33: 635-55. PMID 16941234 DOI: 10.1007/S10928-006-9028-Y |
0.354 |
|
| 2006 |
Qu J, Jusko WJ, Straubinger RM. Utility of cleavable isotope-coded affinity-tagged reagents for quantification of low-copy proteins induced by methylprednisolone using liquid chromatography/tandem mass spectrometry. Analytical Chemistry. 78: 4543-52. PMID 16808464 DOI: 10.1021/Ac0521697 |
0.574 |
|
| 2006 |
Meno-Tetang GM, Li H, Mis S, Pyszczynski N, Heining P, Lowe P, Jusko WJ. Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1480-7. PMID 16751263 DOI: 10.1124/Dmd.105.009001 |
0.797 |
|
| 2006 |
Yao Z, DuBois DC, Almon RR, Jusko WJ. Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle. Pharmaceutical Research. 23: 670-9. PMID 16673181 DOI: 10.1007/S11095-005-9608-3 |
0.521 |
|
| 2006 |
Krzyzanski W, Woo S, Jusko WJ. Pharmacodynamic models for agents that alter production of natural cells with various distributions of lifespans. Journal of Pharmacokinetics and Pharmacodynamics. 33: 125-66. PMID 16565883 DOI: 10.1007/S10928-006-9007-3 |
0.536 |
|
| 2006 |
Hon YY, Jusko WJ, Spratlin VE, Jann MW. Altered methylprednisolone pharmacodynamics in healthy subjects with histamine N-methyltransferase C314T genetic polymorphism. Journal of Clinical Pharmacology. 46: 408-17. PMID 16554448 DOI: 10.1177/0091270006286434 |
0.317 |
|
| 2006 |
Yao Z, Krzyzanski W, Jusko WJ. Assessment of basic indirect pharmacodynamic response models with physiological limits. Journal of Pharmacokinetics and Pharmacodynamics. 33: 167-93. PMID 16547797 DOI: 10.1007/S10928-006-9003-7 |
0.557 |
|
| 2006 |
Samtani MN, Pyszczynski NA, Dubois DC, Almon RR, Jusko WJ. Modeling glucocorticoid-mediated fetal lung maturation: I. Temporal patterns of corticosteroids in rat pregnancy. The Journal of Pharmacology and Experimental Therapeutics. 317: 117-26. PMID 16371449 DOI: 10.1124/Jpet.105.095851 |
0.686 |
|
| 2006 |
Samtani MN, Pyszczynski NA, Dubois DC, Almon RR, Jusko WJ. Modeling glucocorticoid-mediated fetal lung maturation: II. Temporal patterns of gene expression in fetal rat lung. The Journal of Pharmacology and Experimental Therapeutics. 317: 127-38. PMID 16371448 DOI: 10.1124/Jpet.105.095869 |
0.681 |
|
| 2006 |
Drake AS, Michael BT, Wang XH, Sait SJ, Earp JC, Jusko WJ, Ferrone S, Wang ES, Wetzler M. The Effects of Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Monoclonal Antibodies (mAb) Against 11q23 Positive Acute Leukemia Cells. Blood. 108: 4550-4550. DOI: 10.1182/Blood.V108.11.4550.4550 |
0.696 |
|
| 2006 |
Mager DE, Jusko WJ. Mechanistic Pharmacokinetic/Pharmacodynamic Models II Pharmacometrics: the Science of Quantitative Pharmacology. 607-631. DOI: 10.1002/9780470087978.ch23 |
0.497 |
|
| 2005 |
Perez-Ruixo JJ, Kimko HC, Chow AT, Piotrovsky V, Krzyzanski W, Jusko WJ. Population cell life span models for effects of drugs following indirect mechanisms of action. Journal of Pharmacokinetics and Pharmacodynamics. 32: 767-93. PMID 16328102 DOI: 10.1007/S10928-005-0019-1 |
0.656 |
|
| 2005 |
Gordi T, Xie R, Jusko WJ. Semi-mechanistic pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of artemisinin. British Journal of Clinical Pharmacology. 60: 594-604. PMID 16305583 DOI: 10.1111/J.1365-2125.2005.02508.X |
0.379 |
|
| 2005 |
Almon RR, Dubois DC, Jin JY, Jusko WJ. Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time series. The Aaps Journal. 7: E156-94. PMID 16146338 DOI: 10.1208/Aapsj070117 |
0.512 |
|
| 2005 |
Krzyzanski W, Jusko WJ, Wacholtz MC, Minton N, Cheung WK. Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after multiple subcutaneous doses in healthy subjects. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 26: 295-306. PMID 16102948 DOI: 10.1016/J.Ejps.2005.06.010 |
0.417 |
|
| 2005 |
Samtani MN, Jusko WJ. Stability of dexamethasone sodium phosphate in rat plasma. International Journal of Pharmaceutics. 301: 262-6. PMID 16054309 DOI: 10.1016/J.Ijpharm.2005.06.003 |
0.685 |
|
| 2005 |
Almon RR, Lai W, DuBois DC, Jusko WJ. Corticosteroid-regulated genes in rat kidney: mining time series array data. American Journal of Physiology. Endocrinology and Metabolism. 289: E870-82. PMID 15985454 DOI: 10.1152/Ajpendo.00196.2005 |
0.322 |
|
| 2005 |
Samtani MN, Lohle M, Grant A, Nathanielsz PW, Jusko WJ. Betamethasone pharmacokinetics after two prodrug formulations in sheep: implications for antenatal corticosteroid use. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1124-30. PMID 15860658 DOI: 10.1124/Dmd.105.004309 |
0.683 |
|
| 2005 |
Mager DE, Neuteboom B, Jusko WJ. Pharmacokinetics and pharmacodynamics of PEGylated IFN-beta 1a following subcutaneous administration in monkeys. Pharmaceutical Research. 22: 58-61. PMID 15771230 DOI: 10.1007/S11095-004-9009-Z |
0.588 |
|
| 2005 |
Chakraborty A, Yeung S, Pyszczynski NA, Jusko WJ. Pharmacodynamic interactions between recombinant mouse interleukin-10 and prednisolone using a mouse endotoxemia model. Journal of Pharmaceutical Sciences. 94: 590-603. PMID 15666292 DOI: 10.1002/Jps.20257 |
0.641 |
|
| 2005 |
Samtani MN, Jusko WJ. Comparison of dexamethasone pharmacokinetics in female rats after intravenous and intramuscular administration. Biopharmaceutics & Drug Disposition. 26: 85-91. PMID 15654687 DOI: 10.1002/Bdd.435 |
0.722 |
|
| 2005 |
Almon RR, Dubois DC, Jin JY, Jusko WJ. Temporal profiling of the transcriptional basis for the development of corticosteroid-induced insulin resistance in rat muscle. The Journal of Endocrinology. 184: 219-32. PMID 15642798 DOI: 10.1677/Joe.1.05953 |
0.485 |
|
| 2004 |
Earp J, Krzyzanski W, Chakraborty A, Zamacona MK, Jusko WJ. Assessment of drug interactions relevant to pharmacodynamic indirect response models. Journal of Pharmacokinetics and Pharmacodynamics. 31: 345-80. PMID 15669772 DOI: 10.1007/S10928-004-8319-4 |
0.793 |
|
| 2004 |
Samtani MN, Schwab M, Nathanielsz PW, Jusko WJ. Area/moment and compartmental modeling of pharmacokinetics during pregnancy: applications to maternal/fetal exposures to corticosteroids in sheep and rats. Pharmaceutical Research. 21: 2279-92. PMID 15648260 DOI: 10.1007/S11095-004-7681-7 |
0.662 |
|
| 2004 |
Smith P, Bullock JM, Booker BM, Haas CE, Berenson CS, Jusko WJ. The influence of St. John's wort on the pharmacokinetics and protein binding of imatinib mesylate. Pharmacotherapy. 24: 1508-14. PMID 15537555 DOI: 10.1592/Phco.24.16.1508.50958 |
0.354 |
|
| 2004 |
Kamal MA, Jusko WJ. Interactions of prednisolone and other immunosuppressants used in dual treatment of systemic lupus erythematosus in lymphocyte proliferation assays. Journal of Clinical Pharmacology. 44: 1034-45. PMID 15317831 DOI: 10.1177/0091270004267808 |
0.327 |
|
| 2004 |
Ramakrishnan R, Cheung WK, Wacholtz MC, Minton N, Jusko WJ. Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after single and multiple doses in healthy volunteers. Journal of Clinical Pharmacology. 44: 991-1002. PMID 15317827 DOI: 10.1177/0091270004268411 |
0.636 |
|
| 2004 |
Lepist EI, Jusko WJ. Modeling and allometric scaling of s(+)-ketoprofen pharmacokinetics and pharmacodynamics: a retrospective analysis. Journal of Veterinary Pharmacology and Therapeutics. 27: 211-8. PMID 15305849 DOI: 10.1111/J.1365-2885.2004.00579.X |
0.326 |
|
| 2004 |
Almon RR, DuBois DC, Piel WH, Jusko WJ. The genomic response of skeletal muscle to methylprednisolone using microarrays: tailoring data mining to the structure of the pharmacogenomic time series. Pharmacogenomics. 5: 525-52. PMID 15212590 DOI: 10.1517/14622416.5.5.525 |
0.313 |
|
| 2004 |
Samtani MN, Schwab M, Nathanielsz PW, Jusko WJ. Stabilization and HPLC analysis of betamethasone sodium phosphate in plasma. Journal of Pharmaceutical Sciences. 93: 726-32. PMID 14762910 DOI: 10.1002/Jps.10577 |
0.665 |
|
| 2004 |
Jin JY, DuBois DC, Almon RR, Jusko WJ. Receptor/gene-mediated pharmacodynamic effects of methylprednisolone on phosphoenolpyruvate carboxykinase regulation in rat liver. The Journal of Pharmacology and Experimental Therapeutics. 309: 328-39. PMID 14722324 DOI: 10.1124/Jpet.103.061515 |
0.539 |
|
| 2003 |
Almon RR, Chen J, Snyder G, DuBois DC, Jusko WJ, Hoffman EP. In vivo multi-tissue corticosteroid microarray time series available online at Public Expression Profile Resource (PEPR). Pharmacogenomics. 4: 791-9. PMID 14596642 DOI: 10.1517/Phgs.4.6.791.22816 |
0.369 |
|
| 2003 |
Mager DE, Lin SX, Blum RA, Lates CD, Jusko WJ. Dose equivalency evaluation of major corticosteroids: pharmacokinetics and cell trafficking and cortisol dynamics. Journal of Clinical Pharmacology. 43: 1216-27. PMID 14551176 DOI: 10.1177/0091270003258651 |
0.615 |
|
| 2003 |
Zimmerman JJ, Harper D, Getsy J, Jusko WJ. Pharmacokinetic interactions between sirolimus and microemulsion cyclosporine when orally administered jointly and 4 hours apart in healthy volunteers. Journal of Clinical Pharmacology. 43: 1168-76. PMID 14517200 DOI: 10.1177/0091270003257227 |
0.387 |
|
| 2003 |
Almon RR, DuBois DC, Pearson KE, Stephan DA, Jusko WJ. Gene arrays and temporal patterns of drug response: corticosteroid effects on rat liver. Functional & Integrative Genomics. 3: 171-9. PMID 12928814 DOI: 10.1007/S10142-003-0090-X |
0.333 |
|
| 2003 |
Mager DE, Moledina N, Jusko WJ. Relative immunosuppressive potency of therapeutic corticosteroids measured by whole blood lymphocyte proliferation. Journal of Pharmaceutical Sciences. 92: 1521-5. PMID 12820156 DOI: 10.1002/Jps.10402 |
0.584 |
|
| 2003 |
Jin JY, Almon RR, DuBois DC, Jusko WJ. Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays. The Journal of Pharmacology and Experimental Therapeutics. 307: 93-109. PMID 12808002 DOI: 10.1124/Jpet.103.053256 |
0.515 |
|
| 2003 |
Levy G, Mager DE, Cheung WK, Jusko WJ. Comparative pharmacokinetics of coumarin anticoagulants L: Physiologic modeling of S-warfarin in rats and pharmacologic target-mediated warfarin disposition in man. Journal of Pharmaceutical Sciences. 92: 985-94. PMID 12712418 DOI: 10.1002/Jps.10345 |
0.716 |
|
| 2003 |
Mager DE, Wyska E, Jusko WJ. Diversity of mechanism-based pharmacodynamic models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 510-8. PMID 12695336 DOI: 10.1124/Dmd.31.5.510 |
0.574 |
|
| 2003 |
Ramakrishnan R, Cheung WK, Farrell F, Joffee L, Jusko WJ. Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous dose administration in cynomolgus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 306: 324-31. PMID 12676891 DOI: 10.1124/Jpet.102.047191 |
0.609 |
|
| 2003 |
Mager DE, Pyszczynski NA, Jusko WJ. Integrated QSPR--pharmacodynamic model of genomic effects of several corticosteroids. Journal of Pharmaceutical Sciences. 92: 881-9. PMID 12661073 DOI: 10.1002/Jps.10343 |
0.637 |
|
| 2003 |
Mager DE, Neuteboom B, Efthymiopoulos C, Munafo A, Jusko WJ. Receptor-mediated pharmacokinetics and pharmacodynamics of interferon-beta1a in monkeys. The Journal of Pharmacology and Experimental Therapeutics. 306: 262-70. PMID 12660309 DOI: 10.1124/Jpet.103.049502 |
0.62 |
|
| 2003 |
Krzyzanski W, Jusko WJ. Multiple-pool cell lifespan model of hematologic effects of anticancer agents. Journal of Pharmacokinetics and Pharmacodynamics. 29: 311-37. PMID 12518707 DOI: 10.1023/A:1020984823092 |
0.396 |
|
| 2002 |
Mager DE, Jusko WJ. Receptor-mediated pharmacokinetic/pharmacodynamic model of interferon-beta 1a in humans. Pharmaceutical Research. 19: 1537-43. PMID 12425473 DOI: 10.1023/A:1020468902694 |
0.635 |
|
| 2002 |
Booker BM, Magee MH, Blum RA, Lates CD, Jusko WJ. Pharmacokinetic and pharmacodynamic interactions between diltiazem and methylprednisolone in healthy volunteers. Clinical Pharmacology and Therapeutics. 72: 370-82. PMID 12386639 DOI: 10.1067/Mcp.2002.127944 |
0.368 |
|
| 2002 |
Mager DE, Jusko WJ. Quantitative structure-pharmacokinetic/pharmacodynamic relationships of corticosteroids in man. Journal of Pharmaceutical Sciences. 91: 2441-51. PMID 12379930 DOI: 10.1002/Jps.10231 |
0.595 |
|
| 2002 |
Almon RR, DuBois DC, Brandenburg EH, Shi W, Zhang S, Straubinger RM, Jusko WJ. Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis. Journal of Pharmacokinetics and Pharmacodynamics. 29: 103-29. PMID 12361239 DOI: 10.1023/A:1019762323576 |
0.606 |
|
| 2002 |
Ramakrishnan R, DuBois DC, Almon RR, Pyszczynski NA, Jusko WJ. Fifth-generation model for corticosteroid pharmacodynamics: application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats. Journal of Pharmacokinetics and Pharmacodynamics. 29: 1-24. PMID 12194533 DOI: 10.1023/A:1015765201129 |
0.607 |
|
| 2002 |
Bernstein SH, Jusko WJ, Krzyzanski W, Nichol J, Wetzler M. Pharmacodynamic modeling of thrombopoietin, platelet, and megakaryocyte dynamics in patients with acute myeloid leukemia undergoing dose intensive chemotherapy. Journal of Clinical Pharmacology. 42: 501-11. PMID 12017344 DOI: 10.1177/00912700222011553 |
0.345 |
|
| 2002 |
Magee MH, Blum RA, Lates CD, Jusko WJ. Pharmacokinetic/pharmacodynamic model for prednisolone inhibition of whole blood lymphocyte proliferation. British Journal of Clinical Pharmacology. 53: 474-84. PMID 11994053 DOI: 10.1046/J.1365-2125.2002.01567.X |
0.329 |
|
| 2002 |
Chakraborty A, Jusko WJ. Pharmacodynamic interaction of recombinant human interleukin-10 and prednisolone using in vitro whole blood lymphocyte proliferation. Journal of Pharmaceutical Sciences. 91: 1334-42. PMID 11977109 DOI: 10.1002/Jps.3000 |
0.64 |
|
| 2002 |
Li H, Meno-Tetang GM, Chiba K, Arima N, Heining P, Jusko WJ. Pharmacokinetics and cell trafficking dynamics of 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride (FTY720) in cynomolgus monkeys after single oral and intravenous doses. The Journal of Pharmacology and Experimental Therapeutics. 301: 519-26. PMID 11961052 DOI: 10.1124/Jpet.301.2.519 |
0.788 |
|
| 2002 |
Ramakrishnan R, DuBois DC, Almon RR, Pyszczynski NA, Jusko WJ. Pharmacodynamics and pharmacogenomics of methylprednisolone during 7-day infusions in rats. The Journal of Pharmacology and Experimental Therapeutics. 300: 245-56. PMID 11752123 DOI: 10.1124/Jpet.300.1.245 |
0.6 |
|
| 2001 |
Mager DE, Jusko WJ. General pharmacokinetic model for drugs exhibiting target-mediated drug disposition. Journal of Pharmacokinetics and Pharmacodynamics. 28: 507-32. PMID 11999290 DOI: 10.1023/A:1014414520282 |
0.634 |
|
| 2001 |
Meno-Tetang GM, Blum RA, Schwartz KE, Jusko WJ. Effects of oral prasterone (dehydroepiandrosterone) on single-dose pharmacokinetics of oral prednisone and cortisol suppression in normal women. Journal of Clinical Pharmacology. 41: 1195-205. PMID 11697752 DOI: 10.1177/00912700122012742 |
0.383 |
|
| 2001 |
Magee MH, Blum RA, Lates CD, Jusko WJ. Prednisolone pharmacokinetics and pharmacodynamics in relation to sex and race. Journal of Clinical Pharmacology. 41: 1180-94. PMID 11697751 DOI: 10.1177/00912700122012733 |
0.328 |
|
| 2001 |
Ramakrishnan R, Jusko WJ. Interactions of aspirin and salicylic acid with prednisolone for inhibition of lymphocyte proliferation. International Immunopharmacology. 1: 2035-42. PMID 11606034 DOI: 10.1016/S1567-5769(01)00132-1 |
0.564 |
|
| 2001 |
Mager DE, Jusko WJ. Pharmacodynamic modeling of time-dependent transduction systems. Clinical Pharmacology and Therapeutics. 70: 210-6. PMID 11557908 DOI: 10.1067/Mcp.2001.118244 |
0.538 |
|
| 2001 |
Wyska E, Jusko WJ. Approaches to pharmacokinetic/ pharmacodynamic modeling during pregnancy. Seminars in Perinatology. 25: 124-32. PMID 11453607 DOI: 10.1053/Sper.2001.24905 |
0.368 |
|
| 2001 |
Krzyzanski W, Jusko WJ. Indirect pharmacodynamic models for responses with multicompartmental distribution or polyexponential disposition. Journal of Pharmacokinetics and Pharmacodynamics. 28: 57-78. PMID 11253614 DOI: 10.1023/A:1011517718990 |
0.335 |
|
| 2001 |
Levy G, Zamacona MK, Jusko WJ. Developing compliance instructions for drug labeling. Clinical Pharmacology and Therapeutics. 68: 586-91. PMID 11180017 DOI: 10.1067/Mcp.2000.110976 |
0.507 |
|
| 2001 |
Chow FS, Sharma A, Jusko WJ. Modeling interactions between adrenal suppression and T-helper lymphocyte trafficking during multiple dosing of methylprednisolone. Journal of Pharmacokinetics and Biopharmaceutics. 27: 559-75. PMID 11153446 DOI: 10.1023/A:1020974408657 |
0.352 |
|
| 2001 |
Gabrielsson J, Jusko WJ, Alari L. Modeling of dose-response-time data: four examples of estimating the turnover parameters and generating kinetic functions from response profiles. Biopharmaceutics & Drug Disposition. 21: 41-52. PMID 11100906 DOI: 10.1002/1099-081X(200003)21:2<41::Aid-Bdd217>3.0.Co;2-D |
0.415 |
|
| 2000 |
Fasanmade AA, Jusko WJ. Immunodynamics of methylprednisolone induced T-cell trafficking and deactivation using whole blood lymphocyte proliferation techniques in the rat. Biopharmaceutics & Drug Disposition. 20: 255-61. PMID 10594870 DOI: 10.1002/(Sici)1099-081X(199907)20:5<255::Aid-Bdd183>3.0.Co;2-E |
0.325 |
|
| 1999 |
Krzyzanski W, Ramakrishnan R, Jusko WJ. Basic pharmacodynamic models for agents that alter production of natural cells. Journal of Pharmacokinetics and Biopharmaceutics. 27: 467-89. PMID 10948694 DOI: 10.1023/A:1023249813106 |
0.581 |
|
| 1999 |
Meno-Tetang GM, Hon YY, Van Wart S, Jusko WJ. Pharmacokinetic and pharmacodynamic interactions between dehydroepiandrosterone and prednisolone in the rat. Drug Metabolism and Drug Interactions. 15: 51-70. PMID 10707113 DOI: 10.1515/Dmdi.1999.15.1.51 |
0.698 |
|
| 1999 |
Gumbhir-Shah K, Kellerman DJ, DeGraw S, Koch P, Jusko WJ. Pharmacokinetics and pharmacodynamics of cumulative single doses of inhaled salbutamol enantiomers in asthmatic subjects. Pulmonary Pharmacology & Therapeutics. 12: 353-62. PMID 10587476 DOI: 10.1006/Pupt.1999.0217 |
0.343 |
|
| 1999 |
Chakraborty A, Krzyzanski W, Jusko WJ. Mathematical modeling of circadian cortisol concentrations using indirect response models: comparison of several methods. Journal of Pharmacokinetics and Biopharmaceutics. 27: 23-43. PMID 10533696 DOI: 10.1023/A:1020678628317 |
0.353 |
|
| 1999 |
Ferron GM, Pyszczynski NA, Jusko WJ. Pharmacokinetic and pharmacoimmunodynamic interactions between prednisolone and sirolimus in adrenalectomized rats. Journal of Pharmacokinetics and Biopharmaceutics. 27: 1-21. PMID 10533695 DOI: 10.1023/A:1020626611479 |
0.412 |
|
| 1999 |
Sun YN, Jusko WJ. Role of baseline parameters in determining indirect pharmacodynamic responses. Journal of Pharmaceutical Sciences. 88: 987-90. PMID 10514344 DOI: 10.1021/Js9901155 |
0.308 |
|
| 1999 |
Sharma A, Jusko WJ, Fulmor IE, Norton J, Uderman HD, Salazar DE. Pharmacokinetics and pharmacodynamics of avitriptan during intravenous administration in healthy subjects. Journal of Clinical Pharmacology. 39: 685-94. PMID 10392323 DOI: 10.1177/00912709922008326 |
0.405 |
|
| 1999 |
Chakraborty A, Blum RA, Mis SM, Cutler DL, Jusko WJ. Pharmacokinetic and adrenal interactions of IL-10 and prednisone in healthy volunteers. Journal of Clinical Pharmacology. 39: 624-35. PMID 10354967 DOI: 10.1177/00912709922008137 |
0.303 |
|
| 1999 |
Krzyzanski W, Jusko WJ. Characterization of pharmacodynamic recession slopes for direct and indirect response models. Journal of Pharmacokinetics and Biopharmaceutics. 26: 409-36. PMID 10214560 DOI: 10.1023/A:1021012117627 |
0.417 |
|
| 1999 |
Krzyzanski W, Jusko WJ. Mathematical formalism and characteristics of four basic models of indirect pharmacodynamic responses for drug infusions. Journal of Pharmacokinetics and Biopharmaceutics. 26: 385-408. PMID 10214559 DOI: 10.1023/A:1021060000789 |
0.386 |
|
| 1999 |
Flores-Murrieta FJ, Ko HC, Flores-Acevedo DM, López-Muñoz FJ, Jusko WJ, Sale ME, Castañeda-Hernández G. Pharmacokinetic-pharmacodynamic modeling of tolmetin antinociceptive effect in the rat using an indirect response model: a population approach. Journal of Pharmacokinetics and Biopharmaceutics. 26: 547-57. PMID 10205770 DOI: 10.1023/A:1023273100270 |
0.429 |
|
| 1999 |
Meno-Tetang GM, Gobburu JV, Jusko WJ. Influence of gender on prednisolone effects on whole blood T-cell deactivation and trafficking in rats. Journal of Pharmaceutical Sciences. 88: 46-51. PMID 9874701 DOI: 10.1021/Js9802695 |
0.357 |
|
| 1999 |
Sharma A, Slugg PH, Hammett JL, Jusko WJ. Estimation of oral bioavailability of a long half-life drug in healthy subjects. Pharmaceutical Research. 15: 1782-6. PMID 9834003 DOI: 10.1023/A:1011977116543 |
0.341 |
|
| 1999 |
Davis CB, Tobia LP, Kwok DC, Oishi CM, Kheterpal N, Hepburn TW, Benincosa LJ, Chow FS, Jusko WJ. Accumulation of antibody-target complexes and the pharmacodynamics of clotting after single intravenous administration of humanized anti-factor IX monoclonal antibody to rats Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents. 6: 171-179. DOI: 10.1080/107175499266922 |
0.359 |
|
| 1998 |
Sun YN, DuBois DC, Almon RR, Pyszczynski NA, Jusko WJ. Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down- regulation and tyrosine aminotransferase induction in rat liver Journal of Pharmacokinetics and Biopharmaceutics. 26: 619-648. PMID 10485078 DOI: 10.1023/A:1020746822634 |
0.394 |
|
| 1998 |
Sun YN, DuBois DC, Almon RR, Jusko WJ. Fourth-generation model for corticosteroid pharmacodynamics: A model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver Journal of Pharmacokinetics and Biopharmaceutics. 26: 289-317. PMID 10098101 DOI: 10.1023/A:1023233409550 |
0.37 |
|
| 1998 |
Radwanski E, Chakraborty A, Van Wart S, Huhn RD, Cutler DL, Affrime MB, Jusko WJ. Pharmacokinetics and leukocyte responses of recombinant human interleukin-10. Pharmaceutical Research. 15: 1895-901. PMID 9892475 DOI: 10.1023/A:1011918425629 |
0.68 |
|
| 1998 |
Sharma A, Jusko WJ. Characteristics of indirect pharmacodynamic models and applications to clinical drug responses. British Journal of Clinical Pharmacology. 45: 229-39. PMID 9517366 DOI: 10.1046/J.1365-2125.1998.00676.X |
0.364 |
|
| 1998 |
Krzyzanski W, Jusko WJ. Integrated functions for four basic models of indirect pharmacodynamic response. Journal of Pharmaceutical Sciences. 87: 67-72. PMID 9452970 DOI: 10.1021/Js970168R |
0.383 |
|
| 1998 |
Sharma A, Slugg PH, Hammett JL, Jusko WJ. Clinical pharmacokinetics and pharmacodynamics of a new squalene synthase inhibitor, BMS-188494, in healthy volunteers. The Journal of Clinical Pharmacology. 38: 1116-1121. DOI: 10.1177/009127009803801205 |
0.398 |
|
| 1998 |
Gumbhir‐Shah K, Kellerman DJ, DeGraw S, Koch P, Jusko WJ. Pharmacokinetic and pharmacodynamic characteristics and safety of inhaled albuterol enantiomers in healthy volunteers The Journal of Clinical Pharmacology. 38: 1096-1106. DOI: 10.1177/009127009803801203 |
0.33 |
|
| 1997 |
Krzyzanski W, Jusko WJ. Mathematical formalism for the properties of four basic models of indirect pharmacodynamic responses. Journal of Pharmacokinetics and Biopharmaceutics. 25: 107-23. PMID 9353696 DOI: 10.1023/A:1025723927981 |
0.383 |
|
| 1997 |
Sharma A, Jusko WJ. Characterization of four basic models of indirect pharmacodynamic responses. Journal of Pharmacokinetics and Biopharmaceutics. 24: 611-35. PMID 9300353 DOI: 10.1007/Bf02353483 |
0.394 |
|
| 1997 |
Krzyzanski W, Jusko WJ. Application of moment analysis to the sigmoid effect model for drug administered intravenously. Pharmaceutical Research. 14: 949-52. PMID 9244156 DOI: 10.1023/A:1012120421395 |
0.373 |
|
| 1997 |
Jusko WJ, Ferron GM, Mis SM, Kahan BD, Zimmerman JJ. Pharmacokinetics of prednisolone during administration of sirolimus in patients with renal transplants. Journal of Clinical Pharmacology. 36: 1100-6. PMID 9013365 DOI: 10.1002/J.1552-4604.1996.Tb04162.X |
0.363 |
|
| 1997 |
Cheng H, Gong Y, Jusko WJ. A computer program using disposition decomposition analysis in pharmacodynamics. Biopharmaceutics & Drug Disposition. 18: 9-15. PMID 9008265 DOI: 10.1002/(Sici)1099-081X(199701)18:1<9::Aid-Bdd999>3.0.Co;2-4 |
0.31 |
|
| 1997 |
Ferron GM, Rochdi M, Jusko WJ, Scherrmann JM. Oral absorption characteristics and pharmacokinetics of colchicine in healthy volunteers after single and multiple doses. Journal of Clinical Pharmacology. 36: 874-83. PMID 8930773 DOI: 10.1002/J.1552-4604.1996.Tb04753.X |
0.411 |
|
| 1997 |
Cheng H, Jusko WJ. Disposition decomposition analysis for pharmacodynamic modeling of the link compartment. Biopharmaceutics & Drug Disposition. 17: 117-24. PMID 8907718 DOI: 10.1002/(Sici)1099-081X(199603)17:2<117::Aid-Bdd949>3.0.Co;2-A |
0.374 |
|
| 1997 |
Meno-Tetang GM, Hon YY, Jusko WJ. Synergistic interaction between dehydroepiandrosterone and prednisolone in the inhibition of rat lymphocyte proliferation. Immunopharmacology and Immunotoxicology. 18: 443-56. PMID 8872495 DOI: 10.3109/08923979609052746 |
0.331 |
|
| 1996 |
LEVY G, JUSKO WJ. EFFECT OF VISCOSITY ON DRUG ABSORPTION. Journal of Pharmaceutical Sciences. 54: 219-24. PMID 14293807 DOI: 10.1002/Jps.2600540212 |
0.522 |
|
| 1996 |
Mishina EV, Jusko WJ. Liposomal methylprednisolone in rats: dose-proportionality and chronic-dose pharmacokinetics/pharmacodynamics. Pharmaceutical Research. 13: 141-5. PMID 8668664 DOI: 10.1023/A:1016054022750 |
0.335 |
|
| 1996 |
Slayter KL, Ludwig EA, Lew KH, Middleton E, Ferry JJ, Jusko WJ. Oral contraceptive effects on methylprednisolone pharmacokinetics and pharmacodynamics. Clinical Pharmacology and Therapeutics. 59: 312-21. PMID 8653994 DOI: 10.1016/S0009-9236(96)80009-9 |
0.355 |
|
| 1996 |
Jusko WJ. Analysis of tacrolimus (FK 506) in relation to therapeutic drug monitoring. Therapeutic Drug Monitoring. 17: 596-601. PMID 8588227 DOI: 10.1097/00007691-199512000-00009 |
0.323 |
|
| 1996 |
Jusko WJ, Ko HC, Ebling WF. Convergence of direct and indirect pharmacodynamic response models. Journal of Pharmacokinetics and Biopharmaceutics. 23: 5-8; discussion 9-10. PMID 8576844 DOI: 10.1007/Bf02353781 |
0.386 |
|
| 1996 |
Jusko WJ. Historical perspectives on mechanistic pharmacokinetic/pharmacodynamic modelling European Journal of Pharmaceutical Sciences. 4: S17-S18. DOI: 10.1016/S0928-0987(96)00026-7 |
0.356 |
|
| 1995 |
Xu ZX, Sun YN, DuBois DC, Almon RR, Jusko WJ. Third-generation model for corticosteroid pharmacodynamics: Roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver Journal of Pharmacokinetics and Biopharmaceutics. 23: 163-181. PMID 8719235 DOI: 10.1007/Bf02354270 |
0.323 |
|
| 1995 |
Griensven JMTv, Jusko WJ, Lemkes HHPJ, Kroon R, Verhorst CJ, Chiang ST, Cohen AF. Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes Clinical Pharmacology & Therapeutics. 58: 631-640. PMID 8529328 DOI: 10.1016/0009-9236(95)90019-5 |
0.335 |
|
| 1995 |
Milsap RL, Jusko WJ. Pharmacokinetics in the infant. Environmental Health Perspectives. 107-10. PMID 7737034 DOI: 10.1289/Ehp.94102S11107 |
0.325 |
|
| 1995 |
Ko HC, Almon RR, Jusko WJ. Effect of corticosteroid binding globulin on the pharmacokinetics of prednisolone in rats. Pharmaceutical Research. 12: 902-4. PMID 7667198 DOI: 10.1023/A:1016225423795 |
0.31 |
|
| 1995 |
Fasanmade AA, Jusko WJ. Optimizing whole blood lymphocyte proliferation in the rat. Journal of Immunological Methods. 184: 163-7. PMID 7658020 DOI: 10.1016/0022-1759(95)00084-N |
0.302 |
|
| 1995 |
Xu ZX, Lee MJ, Blum RA, Jusko WJ. Pharmacodynamic modeling of prednisolone effects on natural killer cell trafficking. Pharmaceutical Research. 12: 459-63. PMID 7617538 DOI: 10.1023/A:1016229307923 |
0.311 |
|
| 1995 |
DuBois DC, Xu ZX, McKay L, Almon RR, Pyszcznski N, Jusko WJ. Differential dynamics of receptor down-regulation and tyrosine aminotransferase induction following glucocorticoid treatment Journal of Steroid Biochemistry and Molecular Biology. 54: 237-243. PMID 7577705 DOI: 10.1016/0960-0760(95)00139-Q |
0.351 |
|
| 1995 |
Fasanmade AA, Jusko WJ. Effect of halofantrine and its desbutyl metabolite on lymphocyte proliferation dynamics. Life Sciences. 57: PL175-80. PMID 7564875 DOI: 10.1016/0024-3205(95)02097-3 |
0.323 |
|
| 1995 |
Lee MJ, Pyszczynski N, Jusko WJ. Combined inhibition effects of tacrolimus and methylprednisolone on in vitro human lymphocyte proliferation. Immunopharmacology and Immunotoxicology. 17: 335-45. PMID 7544367 DOI: 10.3109/08923979509019755 |
0.363 |
|
| 1995 |
Lee MJ, Straubinger RM, Jusko WJ. Physicochemical, Pharmacokinetic and Pharmacodynamic Evaluation of Liposomal Tacrolimus (FK 506) in Rats Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 1055-1059. PMID 7494802 DOI: 10.1023/A:1016222817860 |
0.602 |
|
| 1995 |
Jusko WJ. Pharmacokinetics and receptor-mediated pharmacodynamics of corticosteroids. Toxicology. 102: 189-96. PMID 7482553 DOI: 10.1016/0300-483X(95)03047-J |
0.427 |
|
| 1995 |
Ko HC, Jusko WJ. Pharmacodynamic Modeling of Finasteride, a 5α-Reductase Inhibitor Pharmacotherapy. 15: 509-511. DOI: 10.1002/J.1875-9114.1995.Tb04389.X |
0.365 |
|
| 1994 |
Milad MA, Ludwig EA, Lew KH, Kohli RK, Jusko WJ. The Pharmacokinetics and Pharmacodynamics of Methylprednisolone in Chronic Renal Failure. American Journal of Therapeutics. 1: 49-57. PMID 11835067 DOI: 10.1097/00045391-199406000-00009 |
0.354 |
|
| 1994 |
Garg V, Jusko WJ. Pharmacodynamic modeling of nonsteroidal anti-inflammatory drugs: Antipyretic effect of ibuprofen [2] Clinical Pharmacology and Therapeutics. 55: 87-88. PMID 8299322 DOI: 10.1038/Clpt.1994.16 |
0.327 |
|
| 1994 |
Milad MA, Jusko WJ. Pharmacodynamic interpretation of adrenocorticotropin stimulation tests. The Annals of Pharmacotherapy. 27: 1195-7. PMID 8251686 DOI: 10.1177/106002809302701008 |
0.331 |
|
| 1994 |
Lew KH, Jusko WJ. Pharmacodynamic modeling of cortisol suppression from fluocortolone. European Journal of Clinical Pharmacology. 45: 581-3. PMID 8157047 DOI: 10.1007/Bf00315319 |
0.44 |
|
| 1994 |
Ermer JC, Hicks DR, Wheeler SC, Kraml M, Jusko WJ. Concomitant etodolac affects neither the unbound clearance nor the pharmacologic effect of warfarin. Clinical Pharmacology and Therapeutics. 55: 305-16. PMID 8143396 DOI: 10.1038/Clpt.1994.31 |
0.41 |
|
| 1994 |
Garg V, Jusko WJ. Bioavailability and reversible metabolism of prednisone and prednisolone in man Biopharmaceutics and Drug Disposition. 15: 163-172. PMID 8011967 DOI: 10.1002/Bdd.2510150208 |
0.36 |
|
| 1994 |
Wald JA, Jusko WJ. Prednisolone pharmacodynamics: leukocyte trafficking in the rat. Life Sciences. 55: PL371-8. PMID 7968208 DOI: 10.1016/0024-3205(94)00693-8 |
0.382 |
|
| 1994 |
Jusko WJ, Ko HC. Physiologic indirect response models characterize diverse types of pharmacodynamic effects. Clinical Pharmacology and Therapeutics. 56: 406-19. PMID 7955802 DOI: 10.1038/Clpt.1994.155 |
0.404 |
|
| 1994 |
Jusko WJ, Pyszczynski NA, Bushway MS, D'Ambrosio R, Mis SM. Fifteen years of operation of a high-performance liquid chromatographic assay for prednisolone, cortisol and prednisone in plasma. Journal of Chromatography. B, Biomedical Applications. 658: 47-54. PMID 7952131 DOI: 10.1016/0378-4347(94)00218-5 |
0.313 |
|
| 1994 |
Mishina EV, Jusko WJ. Inhibition of rat splenocyte proliferation with methylprednisolone: in vivo effect of liposomal formulation. Pharmaceutical Research. 11: 848-54. PMID 7937524 DOI: 10.1023/A:1018929824798 |
0.425 |
|
| 1994 |
Garg V, Jusko WJ. Effects of indomethacin on the pharmacokinetics and pharmacodynamics of prednisolone in rats Journal of Pharmaceutical Sciences. 83: 747-750. PMID 7915309 DOI: 10.1002/Jps.2600830531 |
0.39 |
|
| 1994 |
Milad MA, Ludwig EA, Anné S, Middleton E, Jusko WJ. Pharmacodynamic model for joint exogenous and endogenous corticosteroid suppression of lymphocyte trafficking. Journal of Pharmacokinetics and Biopharmaceutics. 22: 469-80. PMID 7473077 DOI: 10.1007/Bf02353790 |
0.362 |
|
| 1994 |
Troy SM, Hicks DR, Parker VD, Jusko WJ, Rofsky HE, Porter RJ. Differences in pharmacokinetics and comparative bioavailability between premarin® and estratab® in healthy postmenopausal women Current Therapeutic Research. 55: 359-372. DOI: 10.1016/S0011-393X(05)80521-1 |
0.34 |
|
| 1993 |
Jusko WJ. Conceptualization of drug distribution to a hypothetical pharmacodynamic effect compartment. Clinical Pharmacology and Therapeutics. 54: 112-3. PMID 8330459 DOI: 10.1038/Clpt.1993.119 |
0.318 |
|
| 1993 |
Mishina EV, Straubinger RM, Pyszczynski NA, Jusko WJ. Enhancement of Tissue Delivery and Receptor Occupancy of Methylprednisolone in Rats by a Liposomal Formulation Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 10: 1402-1410. PMID 8272400 DOI: 10.1023/A:1018954704886 |
0.614 |
|
| 1993 |
Chow AT, Meek PD, Jusko WJ. High‐pressure liquid chromatographic assay of theophylline in dog feces following oral administration of sustained‐release products Journal of Pharmaceutical Sciences. 82: 956-958. PMID 8229696 DOI: 10.1002/Jps.2600820917 |
0.319 |
|
| 1993 |
Ludwig EA, Kong AN, Camara DS, Jusko WJ. Pharmacokinetics of methylprednisolone hemisuccinate and methylprednisolone in chronic liver disease. Journal of Clinical Pharmacology. 33: 805-10. PMID 8227476 DOI: 10.1002/J.1552-4604.1993.Tb01955.X |
0.347 |
|
| 1993 |
Lew KH, Ludwig EA, Milad MA, Donovan K, Middleton E, Ferry JJ, Jusko WJ. Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics. Clinical Pharmacology and Therapeutics. 54: 402-14. PMID 8222483 DOI: 10.1038/Clpt.1993.167 |
0.33 |
|
| 1993 |
Jusko WJ, Milsap RL. Pharmacokinetic principles of drug distribution in saliva. Annals of the New York Academy of Sciences. 694: 36-47. PMID 8215084 DOI: 10.1111/J.1749-6632.1993.Tb18340.X |
0.317 |
|
| 1993 |
Dayneka NL, Garg V, Jusko WJ. Comparison of four basic models of indirect pharmacodynamic responses Journal of Pharmacokinetics and Biopharmaceutics. 21: 457-478. PMID 8133465 DOI: 10.1007/Bf01061691 |
0.414 |
|
| 1993 |
Piekoszewski W, Jusko WJ. Plasma protein binding of tacrolimus in humans. Journal of Pharmaceutical Sciences. 82: 340-1. PMID 7680714 DOI: 10.1002/Jps.2600820325 |
0.317 |
|
| 1993 |
Haughey DB, Jusko WJ. Receptor-mediated methylprednisolone pharmacodynamics in rats: steroid-induced receptor down-regulation. Journal of Pharmacokinetics and Biopharmaceutics. 20: 333-55. PMID 1362219 DOI: 10.1007/Bf01062462 |
0.307 |
|
| 1992 |
Dove AM, Szefler SJ, Hill MR, Jusko WJ, Larsen GL, Accurso FJ. Altered prednisolone pharmacokinetics in patients with cystic fibrosis. The Journal of Pediatrics. 120: 789-94. PMID 1578318 DOI: 10.1016/S0022-3476(05)80250-1 |
0.356 |
|
| 1992 |
Garg V, Blum R, Wilner KD, Jusko WJ. Effect of the anti-inflammatory agent tenidap on the pharmacokinetics and pharmacodynamics of prednisolone. Journal of Clinical Pharmacology. 32: 222-30. PMID 1564126 DOI: 10.1002/J.1552-4604.1992.Tb03830.X |
0.378 |
|
| 1992 |
Haughey DB, Jusko WJ. Bioavailability and nonlinear disposition of methylprednisolone and methylprednisone in the rat. Journal of Pharmaceutical Sciences. 81: 117-21. PMID 1545348 DOI: 10.1002/Jps.2600810203 |
0.383 |
|
| 1992 |
Fisher LE, Ludwig EA, Wald JA, Sloan RR, Middleton E, Jusko WJ. Pharmacokinetics and pharmacodynamics of methylprednisolone when administered at 8 am versus 4 pm. Clinical Pharmacology and Therapeutics. 51: 677-88. PMID 1535301 DOI: 10.1038/Clpt.1992.80 |
0.401 |
|
| 1992 |
Klamerus KJ, Moloney K, Rudolph RL, Sisenwine SF, Jusko WJ, Chiang ST. Introduction of a Composite Parameter to the Pharmacokinetics of Venlafaxine and its Active O‐Desmethyl Metabolite The Journal of Clinical Pharmacology. 32: 716-724. PMID 1487561 DOI: 10.1002/J.1552-4604.1992.Tb03875.X |
0.363 |
|
| 1992 |
Fisher LE, Ludwig EA, Jusko WJ. Pharmacoimmunodynamics of methylprednisolone: trafficking of helper T lymphocytes. Journal of Pharmacokinetics and Biopharmaceutics. 20: 319-31. PMID 1479558 DOI: 10.1007/Bf01062461 |
0.369 |
|
| 1992 |
Wald JA, Jusko WJ. Corticosteroid pharmacodynamic modeling: osteocalcin suppression by prednisolone. Pharmaceutical Research. 9: 1096-8. PMID 1409384 DOI: 10.1023/A:1015875016041 |
0.328 |
|
| 1992 |
Wald JA, Law RM, Ludwig EA, Sloan RR, Middleton E, Jusko WJ. Evaluation of dose-related pharmacokinetics and pharmacodynamics of prednisolone in man. Journal of Pharmacokinetics and Biopharmaceutics. 20: 567-89. PMID 1302763 DOI: 10.1007/Bf01064420 |
0.432 |
|
| 1991 |
Cheng HY, Jusko WJ. Drug redistribution and mean transit time concepts for nonlinear pharmacokinetic systems. Biopharmaceutics & Drug Disposition. 12: 73-9. PMID 2039813 DOI: 10.1002/Bdd.2510120108 |
0.337 |
|
| 1991 |
Veng-Pedersen P, Cheng HY, Jusko WJ. Regarding dose-independent pharmacokinetic parameters in nonlinear pharmacokinetics. Journal of Pharmaceutical Sciences. 80: 608-12. PMID 1941554 DOI: 10.1002/Jps.2600800622 |
0.311 |
|
| 1991 |
Cheng H, Jusko WJ, Gillespie WR. Relationships between the area under the first moment curve after single bolus injection and the integral of plasma concentrations after constant-rate intravenous infusion. Journal of Pharmaceutical Sciences. 80: 507-10. PMID 1880736 DOI: 10.1002/Jps.2600800523 |
0.355 |
|
| 1991 |
Kong AN, Jusko WJ. Disposition of methylprednisolone and its sodium succinate prodrug in vivo and in perfused liver of rats: nonlinear and sequential first-pass elimination. Journal of Pharmaceutical Sciences. 80: 409-15. PMID 1880717 DOI: 10.1002/Jps.2600800502 |
0.347 |
|
| 1991 |
Cheng HY, Jusko WJ. Mean residence times and distribution volumes for drugs undergoing linear reversible metabolism and tissue distribution and linear or nonlinear elimination from the central compartments. Pharmaceutical Research. 8: 508-11. PMID 1871048 DOI: 10.1023/A:1015811514050 |
0.333 |
|
| 1991 |
Yamashita SK, Ludwig EA, Middleton E, Jusko WJ. Lack of pharmacokinetic and pharmacodynamic interactions between ketoconazole and prednisolone. Clinical Pharmacology and Therapeutics. 49: 558-70. PMID 1827622 DOI: 10.1038/Clpt.1991.66 |
0.415 |
|
| 1991 |
Wald JA, Salazar DE, Cheng H, Jusko WJ. Two-compartment basophil cell trafficking model for methylprednisolone pharmacodynamics Journal of Pharmacokinetics and Biopharmaceutics. 19: 521-536. PMID 1783990 DOI: 10.1007/Bf01062961 |
0.401 |
|
| 1990 |
Jungbluth GL, Jusko WJ. Ion-paired reversed-phase high-performance liquid chromatography assay for determination of ceftriaxone in human plasma and urine. Journal of Pharmaceutical Sciences. 78: 968-70. PMID 2621584 DOI: 10.1002/Jps.2600781118 |
0.307 |
|
| 1990 |
Tornatore KM, Morse GD, Jusko WJ, Walshe JJ. Methylprednisolone disposition in renal transplant recipients receiving triple-drug immunosuppression. Transplantation. 48: 962-5. PMID 2595785 DOI: 10.1097/00007890-198912000-00013 |
0.352 |
|
| 1990 |
Cheng HY, Jusko WJ. Effects of variation in drug elimination on five methods for assessing zero-order drug absorption rates. Pharmaceutical Research. 7: 76-9. PMID 2300540 DOI: 10.1023/A:1015843811150 |
0.334 |
|
| 1990 |
Chow AT, Jusko WJ. Michaelis-Menten metabolite formation kinetics: Equations relating area under the curve and metabolite recovery to the administered dose Journal of Pharmaceutical Sciences. 79: 902-906. PMID 2280360 DOI: 10.1002/Jps.2600791012 |
0.378 |
|
| 1990 |
Huang ML, Jusko WJ. Nonlinear pharmacokinetics and interconversion of prednisolone and prednisone in rats Journal of Pharmacokinetics and Biopharmaceutics. 18: 401-421. PMID 2266496 DOI: 10.1007/Bf01061702 |
0.391 |
|
| 1990 |
Reiss WG, Slaughter RL, Ludwig EA, Middleton E, Jusko WJ. Steroid dose sparing: pharmacodynamic responses to single versus divided doses of methylprednisolone in man. The Journal of Allergy and Clinical Immunology. 85: 1058-66. PMID 2191992 DOI: 10.1016/0091-6749(90)90051-5 |
0.424 |
|
| 1990 |
Nichols AI, Jusko WJ. Receptor-mediated prednisolone pharmacodynamics in rats: model verification using a dose-sparing regimen. Journal of Pharmacokinetics and Biopharmaceutics. 18: 189-208. PMID 1974305 DOI: 10.1007/Bf01062199 |
0.4 |
|
| 1990 |
Kong A, Jungbluth GL, Pasko MT, Beam TR, Jusko WJ. Pharmacokinetics of methylprednisolone sodium succinate and methylprednisolone in patients undergoing cardiopulmonary bypass. Pharmacotherapy. 10: 29-34. DOI: 10.1002/J.1875-9114.1990.Tb02547.X |
0.343 |
|
| 1990 |
Jusko WJ. Corticosteroid Pharmacodynamics: Models for a Broad Array of Receptor-Mediated Pharmacologic Effects The Journal of Clinical Pharmacology. 30: 303-310. DOI: 10.1002/J.1552-4604.1990.Tb03598.X |
0.357 |
|
| 1989 |
Cheng HY, Jusko WJ. Mean residence time concepts for pharmacokinetic systems with nonlinear drug elimination described by the Michaelis-Menten equation. Pharmaceutical Research. 5: 156-64. PMID 3244627 DOI: 10.1023/A:1015960806202 |
0.356 |
|
| 1989 |
Haughey DB, Jusko WJ. Analysis of methylprednisolone, methylprednisone and corticosterone for assessment of methylprednisolone disposition in the rat. Journal of Chromatography. 430: 241-8. PMID 3235500 DOI: 10.1016/S0378-4347(00)83159-X |
0.344 |
|
| 1989 |
Cheng HY, Jusko WJ. Relationships between steady-state and single-dose plasma drug concentrations for pharmacokinetic systems with nonlinear elimination. Biopharmaceutics & Drug Disposition. 10: 513-28. PMID 2804255 DOI: 10.1002/Bdd.2510100509 |
0.39 |
|
| 1989 |
Jungbluth GL, Pasko MT, Beam TR, Jusko WJ. Ceftriaxone disposition in open-heart surgery patients. Antimicrobial Agents and Chemotherapy. 33: 850-6. PMID 2764536 DOI: 10.1128/Aac.33.6.850 |
0.387 |
|
| 1989 |
Jungbluth GL, Jusko WJ. Dose-dependent pharmacokinetics of mezlocillin in rats. Antimicrobial Agents and Chemotherapy. 33: 839-43. PMID 2764534 DOI: 10.1128/Aac.33.6.839 |
0.41 |
|
| 1989 |
Cheng H, Jusko WJ. The area function method for assessing the drug absorption rate in linear systems with zero-order input. Pharmaceutical Research. 6: 133-9. PMID 2762213 DOI: 10.1023/A:1015928509101 |
0.363 |
|
| 1989 |
Cheng HY, Jusko WJ. Application of mean residence-time concepts to pharmacokinetic systems with noninstantaneous input and nonlinear elimination. Pharmaceutical Research. 6: 4-12. PMID 2717515 DOI: 10.1023/A:1015883131875 |
0.371 |
|
| 1989 |
Cheng HY, Jusko WJ. An area function method for calculating the apparent elimination rate constant of a metabolite. Journal of Pharmacokinetics and Biopharmaceutics. 17: 125-30. PMID 2715930 DOI: 10.1007/Bf01059091 |
0.322 |
|
| 1989 |
Kong AN, Ludwig EA, Slaughter RL, DiStefano PM, DeMasi J, Middleton E, Jusko WJ. Pharmacokinetics and pharmacodynamic modeling of direct suppression effects of methylprednisolone on serum cortisol and blood histamine in human subjects. Clinical Pharmacology and Therapeutics. 46: 616-28. PMID 2689044 DOI: 10.1038/Clpt.1989.196 |
0.42 |
|
| 1989 |
Jusko WJ. Pharmacokinetics of capacity-limited systems. Journal of Clinical Pharmacology. 29: 488-93. PMID 2666450 DOI: 10.1002/J.1552-4604.1989.Tb03369.X |
0.34 |
|
| 1989 |
Ludwig EA, Slaughter RL, Savliwala M, Brass C, Jusko WJ. Steroid-specific effects of ketoconazole on corticosteroid disposition: unaltered prednisolone elimination. Dicp : the Annals of Pharmacotherapy. 23: 858-61. PMID 2596127 DOI: 10.1177/106002808902301104 |
0.368 |
|
| 1989 |
Nichols AI, Boudinot FD, Jusko WJ. Second generation model for prednisolone pharmacodynamics in the rat. Journal of Pharmacokinetics and Biopharmaceutics. 17: 209-27. PMID 2571711 DOI: 10.1007/Bf01059029 |
0.685 |
|
| 1989 |
Giacoia GP, Jungbluth GL, Jusko WJ. Effect of Formula Feeding on Oral Absorption of Caffeine in
Premature Infants Developmental Pharmacology and Therapeutics. 12: 205-210. DOI: 10.1159/000480948 |
0.338 |
|
| 1988 |
Janicke DM, Parker SW, Cafarell RF, Apicella MA, Jusko WJ. Pharmacokinetics of two multiple-dose mezlocillin regimens. Antimicrobial Agents and Chemotherapy. 32: 777-9. PMID 3395106 DOI: 10.1128/Aac.32.5.777 |
0.367 |
|
| 1988 |
Kong AN, Jusko WJ. Definitions and applications of mean transit and residence times in reference to the two-compartment mammillary plasma clearance model. Journal of Pharmaceutical Sciences. 77: 157-65. PMID 3361431 DOI: 10.1002/Jps.2600770213 |
0.364 |
|
| 1988 |
Green CG, Kraus CK, Lemanske RF, Farrell PM, Jusko WJ. Rapid methylprednisolone clearance in a patient with cystic fibrosis. Drug Intelligence & Clinical Pharmacy. 22: 876-8. PMID 3234253 DOI: 10.1177/106002808802201107 |
0.329 |
|
| 1988 |
SUTFIN TA, PERINI GI, MOLNAR G, JUSKO WJ. Multiple-Dose Pharmacokinetics of Imipramine and Its Major Active and Conjugated Metabolites in Depressed Patients Journal of Clinical Psychopharmacology. 8: 48???52. DOI: 10.1097/00004714-198802000-00009 |
0.314 |
|
| 1987 |
Boudinot FD, Jusko WJ. Dose-dependent pharmacokinetics of prednisolone in normal and adrenalectomized rats. Journal of Pharmacokinetics and Biopharmaceutics. 14: 453-67. PMID 3806371 DOI: 10.1007/Bf01059655 |
0.681 |
|
| 1987 |
Chow AT, Jusko WJ. Application of Moment Analysis to Nonlinear Drug Disposition Described by the Michaelis–Menten Equation Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 4: 59-61. PMID 3508531 DOI: 10.1023/A:1016486012446 |
0.343 |
|
| 1987 |
Ebling WF, Rich SA, Szefler SJ, Jusko WJ. Troleandomycin effects on methylprednisolone and methylprednisone interconversion and disposition in the rabbit. European Journal of Drug Metabolism and Pharmacokinetics. 12: 50-7. PMID 3497038 DOI: 10.1007/Bf03189861 |
0.415 |
|
| 1987 |
Kandrotas RJ, Slaughter RL, Brass C, Jusko WJ. Ketoconazole effects on methylprednisolone disposition and their joint suppression of endogenous cortisol. Clinical Pharmacology and Therapeutics. 42: 465-70. PMID 3311551 DOI: 10.1038/Clpt.1987.179 |
0.382 |
|
| 1987 |
Boudinot FD, D'Ambrosio R, Jusko WJ. Receptor-mediated pharmacodynamics of prednisolone in the rat. Journal of Pharmacokinetics and Biopharmaceutics. 14: 469-93. PMID 2879901 DOI: 10.1007/Bf01059656 |
0.66 |
|
| 1986 |
Szefler SJ, Ebling WF, Georgitis JW, Jusko WJ. Methylprednisolone versus prednisolone pharmacokinetics in relation to dose in adults. European Journal of Clinical Pharmacology. 30: 323-9. PMID 3732369 DOI: 10.1007/Bf00541537 |
0.367 |
|
| 1986 |
Janicke DM, Morse GD, Apicella MA, Jusko WJ, Walshe JJ. Pharmacokinetic modeling of bidirectional transfer during peritoneal dialysis. Clinical Pharmacology and Therapeutics. 40: 209-18. PMID 3731683 DOI: 10.1038/Clpt.1986.165 |
0.38 |
|
| 1986 |
Glynn AM, Slaughter RL, Brass C, D'Ambrosio R, Jusko WJ. Effects of ketoconazole on methylprednisolone pharmacokinetics and cortisol secretion. Clinical Pharmacology and Therapeutics. 39: 654-9. PMID 3709030 DOI: 10.1038/Clpt.1986.114 |
0.369 |
|
| 1985 |
Green AW, Ebling WF, Gardner MJ, Jusko WJ. Cimetidine-methylprednisolone-theophylline metabolic interaction. The American Journal of Medicine. 77: 1115-8. PMID 6507464 DOI: 10.1016/0002-9343(84)90199-2 |
0.389 |
|
| 1985 |
Janicke DM, Cafarell RF, Parker SW, Apicella MA, Jusko WJ. Pharmacokinetics of aztreonam in patients with gram-negative infections. Antimicrobial Agents and Chemotherapy. 27: 16-20. PMID 4039117 DOI: 10.1128/Aac.27.1.16 |
0.309 |
|
| 1985 |
Morse G, Janicke D, Cafarell R, Piontek K, Apicella M, Jusko WJ, Walshe J. Moxalactam epimer disposition in patients undergoing continuous ambulatory peritoneal dialysis. Clinical Pharmacology and Therapeutics. 38: 150-6. PMID 4017417 DOI: 10.1038/Clpt.1985.151 |
0.328 |
|
| 1985 |
Boudinot FD, Homon CA, Jusko WJ, Ruelius HW. Protein binding of oxazepam and its glucuronide conjugates to human albumin. Biochemical Pharmacology. 34: 2115-21. PMID 4004929 DOI: 10.1016/0006-2952(85)90404-6 |
0.624 |
|
| 1984 |
Janicke DM, Rubio TT, Wirth FH, Karotkin EH, Jusko WJ. Developmental pharmacokinetics of mezlocillin in newborn infants. The Journal of Pediatrics. 104: 773-81. PMID 6716226 DOI: 10.1016/S0022-3476(84)80966-X |
0.329 |
|
| 1984 |
Boudinot FD, Jusko WJ. Plasma protein binding interaction of prednisone and prednisolone. Journal of Steroid Biochemistry. 21: 337-9. PMID 6492791 DOI: 10.1016/0022-4731(84)90288-7 |
0.613 |
|
| 1984 |
Gengo FM, Schentag JJ, Jusko WJ. Pharmacokinetics of capacity-limited tissue distribution of methicillin in rabbits. Journal of Pharmaceutical Sciences. 73: 867-73. PMID 6470946 DOI: 10.1002/Jps.2600730703 |
0.363 |
|
| 1984 |
Sutfin TA, DeVane CL, Jusko WJ. The analysis and disposition of imipramine and its active metabolites in man. Psychopharmacology. 82: 310-7. PMID 6427820 DOI: 10.1007/Bf00427676 |
0.377 |
|
| 1984 |
Lui N, Almon RR, Jusko WJ. Comparison of filtration and equilibrium dialysis methods for [3H]imipramine binding to human platelets. Analytical Biochemistry. 139: 42-57. PMID 6331229 DOI: 10.1016/0003-2697(84)90387-7 |
0.333 |
|
| 1984 |
Boudinot FD, Jusko WJ. Fluid shifts and other factors affecting plasma protein binding of prednisolone by equilibrium dialysis. Journal of Pharmaceutical Sciences. 73: 774-80. PMID 6204037 DOI: 10.1002/Jps.2600730617 |
0.638 |
|
| 1984 |
Sutfin TA, D'Ambrosio R, Jusko WJ. Liquid-chromatographic determination of eight tri- and tetracyclic antidepressants and their major active metabolites. Clinical Chemistry. 30: 471-474. DOI: 10.1093/Clinchem/30.3.471 |
0.34 |
|
| 1983 |
Assael BM, Banfi G, Appiani AC, Edefonti A, Jusko WJ. Disposition of pulse dose methylprednisolone in adult and paediatric patients with the nephrotic syndrome. European Journal of Clinical Pharmacology. 23: 429-33. PMID 7151847 DOI: 10.1007/Bf00605993 |
0.371 |
|
| 1983 |
Milsap RL, Jusko WJ. Binding of prednisolone to alpha 1-acid glycoprotein. Journal of Steroid Biochemistry. 18: 191-4. PMID 6843123 DOI: 10.1016/0022-4731(83)90087-0 |
0.3 |
|
| 1983 |
Devane CL, Jusko WJ. Drug and metabolite concentrations combined in predicting steady-state concentrations from test doses. Biopharmaceutics & Drug Disposition. 4: 19-29. PMID 6839000 DOI: 10.1002/Bdd.2510040105 |
0.393 |
|
| 1983 |
Boekenoogen SJ, Szefler SJ, Jusko WJ. Prednisolone disposition and protein binding in oral contraceptive users. The Journal of Clinical Endocrinology and Metabolism. 56: 702-9. PMID 6833459 DOI: 10.1210/Jcem-56-4-702 |
0.333 |
|
| 1983 |
Milsap RL, George DE, Szefler SJ, Murray KA, Lebenthal E, Jusko WJ. Effect of inflammatory bowel disease on absorption and disposition of prednisolone. Digestive Diseases and Sciences. 28: 161-8. PMID 6825536 DOI: 10.1007/Bf01315146 |
0.302 |
|
| 1983 |
Jusko WJ, Rose JQ. Monitoring prednisone and prednisolone. Therapeutic Drug Monitoring. 2: 169-76. PMID 6762710 DOI: 10.1097/00007691-198004000-00011 |
0.404 |
|
| 1982 |
Rocci ML, Jusko WJ. Dose-dependent protein binding and disposition of prednisolone in rabbits. Journal of Pharmaceutical Sciences. 70: 1201-4. PMID 7299663 DOI: 10.1002/Jps.2600701105 |
0.377 |
|
| 1982 |
Tornatore KM, Kanarkowski R, McCarthy TL, Gardner MJ, Yurchak AM, Jusko WJ. Effect of chronic oral contraceptive steroids on theophylline disposition. European Journal of Clinical Pharmacology. 23: 129-34. PMID 7140802 DOI: 10.1007/Bf00545966 |
0.303 |
|
| 1982 |
Potter WZ, Calil HM, Sutfin TA, Zavadil AP, Jusko WJ, Rapoport J, Goodwin FK. Active metabolites of imipramine and desipramine in man. Clinical Pharmacology and Therapeutics. 31: 393-401. PMID 7060321 DOI: 10.1038/Clpt.1982.50 |
0.303 |
|
| 1982 |
Szefler SJ, Brenner M, Jusko WJ, Spector SL, Flesher KA, Ellis EF. Dose- and time-related effect of troleandomycin on methylprednisolone elimination. Clinical Pharmacology and Therapeutics. 32: 166-71. PMID 6980076 DOI: 10.1038/Clpt.1982.143 |
0.343 |
|
| 1982 |
Mangione A, Boudinot FD, Schultz RM, Jusko WJ. Dose-dependent pharmacokinetics of mezlocillin in relation to renal impairment. Antimicrobial Agents and Chemotherapy. 21: 428-35. PMID 6213190 DOI: 10.1128/Aac.21.3.428 |
0.656 |
|
| 1982 |
Mangione A, Janicke DM, Boudinot FD, Schultz RM, Jusko WJ. Dose-dependent pharmacokinetics of mezlocillin in subjects with normal and impaired renal function. The Journal of Antimicrobial Chemotherapy. 81-5. PMID 6210686 DOI: 10.1093/jac/9.suppl_A.81 |
0.586 |
|
| 1981 |
Rose JQ, Nickelsen JA, Ellis EF, Middleton E, Jusko WJ. Prednisolone disposition in steroid-dependent asthmatic children. The Journal of Allergy and Clinical Immunology. 67: 188-93. PMID 7462536 DOI: 10.1016/0091-6749(81)90060-9 |
0.351 |
|
| 1981 |
DeVane CL, Savett M, Jusko WJ. Desipramine and 2-hydroxy-desipramine pharmacokinetics in normal volunteers. European Journal of Clinical Pharmacology. 19: 61-4. PMID 7461025 DOI: 10.1007/Bf00558386 |
0.412 |
|
| 1981 |
Mackichan JJ, Pyszczynski DR, Jusko WJ. Dose-dependent disposition of oral propranolol in normal subjects. Biopharmaceutics & Drug Disposition. 1: 159-66. PMID 7448344 DOI: 10.1002/Bdd.2510010403 |
0.395 |
|
| 1981 |
Rose JQ, Yurchak AM, Jusko WJ. Dose dependent pharmacokinetics of prednisone and prednisolone in man. Journal of Pharmacokinetics and Biopharmaceutics. 9: 389-417. PMID 7310640 DOI: 10.1007/Bf01060885 |
0.394 |
|
| 1981 |
DeVane CL, Jusko WJ. Plasma concentration monitoring of hydroxylated metabolites of imipramine and desipramine. Drug Intelligence & Clinical Pharmacy. 15: 263-6. PMID 7274042 DOI: 10.1177/106002808101500403 |
0.307 |
|
| 1981 |
Rose JQ, Yurchak AM, Meikle AW, Jusko WJ. Effect of smoking on prednisone, prednisolone, and dexamethasone pharmacokinetics. Journal of Pharmacokinetics and Biopharmaceutics. 9: 1-14. PMID 7229914 DOI: 10.1007/Bf01059339 |
0.36 |
|
| 1981 |
Janicke DM, Mangione A, Schultz RW, Jusko WJ. Mezlocillin disposition in chronic hemodialysis patients Antimicrobial Agents and Chemotherapy. 20: 590-594. PMID 6459760 DOI: 10.1128/Aac.20.5.590 |
0.364 |
|
| 1980 |
Rose JQ, Nickelsen JA, Middleton E, Yurchak AM, Park BH, Jusko WJ. Prednisolone disposition in steroid-dependent asthmatics. The Journal of Allergy and Clinical Immunology. 66: 366-73. PMID 7440853 DOI: 10.1016/0091-6749(80)90115-3 |
0.392 |
|
| 1980 |
Janssen FW, Jusko WJ, Chiang ST, Kirkman SK, Southgate PJ, Coleman AJ, Ruelius HW. Metabolism and kinetics of oxaprozin in normal subjects. Clinical Pharmacology and Therapeutics. 27: 352-62. PMID 7357792 DOI: 10.1038/Clpt.1980.47 |
0.409 |
|
| 1979 |
Lima JJ, Goldfarb AL, Conti DR, Golden LH, Bascomb BL, Benedetti GM, Jusko WJ. Safety and efficacy of procainamide infusions. The American Journal of Cardiology. 43: 98-105. PMID 758776 DOI: 10.1016/0002-9149(79)90051-1 |
0.335 |
|
| 1979 |
Rose JQ, Jusko WJ, Nickelsen JA, Green OC. Prednisolone pharmacokinetics in relation to dose. The Journal of Pediatrics. 94: 1014-5. PMID 448518 DOI: 10.1016/S0022-3476(79)80261-9 |
0.324 |
|
| 1979 |
Jusko WJ, Gardner MJ, Mangione A, Schentag JJ, Koup JR, Vance JW. Factors affecting theophylline clearances: Age, tobacco, marijuana, cirrhosis, congestive heart failure, obesity, oral contraceptives, benzodiazepines, barbiturates, and ethanol Journal of Pharmaceutical Sciences. 68: 1358-1366. PMID 41932 DOI: 10.1002/Jps.2600681106 |
0.324 |
|
| 1979 |
MacKichan JJ, Jusko WJ, Duffner PK, Cohen ME. Liquid-chromatographic assay of diazepam and its major metabolites in plasma. Clinical Chemistry. 25: 856-859. DOI: 10.1093/Clinchem/25.6.856 |
0.306 |
|
| 1978 |
Jusko WJ, Gretch M. Plasma and tissue protein binding of drugs in pharmacokinetics. Drug Metabolism Reviews. 5: 43-140. PMID 829788 DOI: 10.3109/03602537608995839 |
0.338 |
|
| 1978 |
Owerbach J, Johnson NF, Bates TR, Pieniaszek HJ, Jusko WJ. High-performance liquid chromatographic assay of sulfapyridine and acetylsulfapyridine in biological fluids. Journal of Pharmaceutical Sciences. 67: 1250-3. PMID 690830 DOI: 10.1002/Jps.2600670916 |
0.303 |
|
| 1978 |
Colburn WA, Schentag JJ, Jusko WJ, Gibaldi M. A model for the prospective identification of the prenephrotoxic state during gentamicin therapy. Journal of Pharmacokinetics and Biopharmaceutics. 6: 179-86. PMID 671224 DOI: 10.1007/Bf01312260 |
0.321 |
|
| 1978 |
Lima JJ, Conti DR, Goldfarb AL, Golden LH, Jusko WJ. Pharmacokinetic approach to intravenous procainamide therapy. European Journal of Clinical Pharmacology. 13: 303-8. PMID 668789 DOI: 10.1007/Bf00716367 |
0.322 |
|
| 1978 |
Schentag JJ, Lasezkay G, Cumbo TJ, Plaut ME, Jusko WJ. Accumulation pharmacokinetics of tobramycin. Antimicrobial Agents and Chemotherapy. 13: 649-56. PMID 666293 DOI: 10.1128/Aac.13.4.649 |
0.401 |
|
| 1978 |
Lima JJ, Jusko WJ. Determination of procainamide acetylator status. Clinical Pharmacology and Therapeutics. 23: 25-9. PMID 618707 DOI: 10.1002/Cpt197823125 |
0.324 |
|
| 1977 |
Schentag JJ, Jusko WJ, Vance JW, Cumbo TJ, Abrutyn E, DeLattre M, Gerbracht LM. Gentamicin disposition and tissue accumulation on multiple dosing Journal of Pharmacokinetics and Biopharmaceutics. 5: 559-577. PMID 599407 DOI: 10.1007/Bf01059684 |
0.372 |
|
| 1977 |
Yaffe SJ, Gerbracht LM, Mosovich LL, Mattar ME, Danish M, Jusko WJ. Pharmacokinetics of methicillin in patients with cystic fibrosis. The Journal of Infectious Diseases. 135: 828-31. PMID 404369 DOI: 10.1093/Infdis/135.5.828 |
0.323 |
|
| 1977 |
Schentag JJ, Jusko WJ. Renal clearance and tissue accumulation of gentamicin. Clinical Pharmacology and Therapeutics. 22: 364-70. PMID 330081 DOI: 10.1002/Cpt1977223364 |
0.391 |
|
| 1976 |
Jusko WJ, Koup JR, Alván G. Nonlinear assessment of phenytoin bioavailability. Journal of Pharmacokinetics and Biopharmaceutics. 4: 327-36. PMID 978395 DOI: 10.1007/Bf01063122 |
0.327 |
|
| 1976 |
Jusko WJ, Baliah T, Kim KH, Gerbracht LM, Yaffe SJ. Pharmacokinetics of gentamicin during peritoneal dialysis in children. Kidney International. 9: 430-8. PMID 940277 DOI: 10.1038/Ki.1976.53 |
0.334 |
|
| 1976 |
Giacoia G, Jusko WJ, Menke J, Koup JR. Theophylline pharmacokinetics in premature infants with apnea. The Journal of Pediatrics. 89: 829-32. PMID 789845 DOI: 10.1016/S0022-3476(76)80818-9 |
0.338 |
|
| 1976 |
Koup JR, Jusko WJ, Goldfarb AL. pH-dependent secretion of procainamide into saliva. Journal of Pharmaceutical Sciences. 64: 2008-10. PMID 1514 DOI: 10.1002/Jps.2600641226 |
0.318 |
|
| 1976 |
Koup JR, Schentag JJ, Vance JW, Kuritzky PM, Pyszczynski DR, Jusko WJ. System for Clinical Pharmacokinetic Monitoring of Theophylline Therapy American Journal of Health-System Pharmacy. 33: 949-957. DOI: 10.1093/Ajhp/33.9.949 |
0.321 |
|
| 1975 |
Lewis GP, Jusko WJ. Pharmacokinetics of ampicillin in cirrhosis. Clinical Pharmacology and Therapeutics. 18: 475-84. PMID 1164828 DOI: 10.1002/Cpt1975184475 |
0.349 |
|
| 1975 |
Koup JR, Greenblatt DJ, Jusko WJ, Smith TW, Koch-Weser J. Pharmacokinetics of digoxin in normal subjects after intravenous bolus and infusion doses. Journal of Pharmacokinetics and Biopharmaceutics. 3: 181-92. PMID 1159622 DOI: 10.1007/Bf01067907 |
0.353 |
|
| 1975 |
Koup JR, Jusko WJ, Elwood CM, Kohli RK. Digoxin pharmacokinetics: role of renal failure in dosage regimen design. Clinical Pharmacology and Therapeutics. 18: 9-21. PMID 1149366 DOI: 10.1002/Cpt19751819 |
0.33 |
|
| 1975 |
Lalka D, Jusko WJ, Bardos TJ. Reactions of 2,2-dimethylaziridine-type alkylating agents in biological systems II: comparative pharmacokinetics in dogs. Journal of Pharmaceutical Sciences. 64: 230-5. PMID 236372 DOI: 10.1002/Jps.2600640208 |
0.361 |
|
| 1975 |
Jusko WJ, Slaunwhite WR, Aceto T. Partial pharmacodynamic model for the circadian-episodic secretion of cortisol in man. The Journal of Clinical Endocrinology and Metabolism. 40: 278-89. PMID 163972 DOI: 10.1210/Jcem-40-2-278 |
0.341 |
|
| 1974 |
Danish M, Schultz R, Jusko WJ. Pharmacokinetics of gentamicin and kanamycin during hemodialysis. Antimicrobial Agents and Chemotherapy. 6: 841-7. PMID 4451356 DOI: 10.1128/Aac.6.6.841 |
0.366 |
|
| 1974 |
Mattar ME, Jusko WJ, Gerbracht L, Mosovich L, Yaffe SJ. PHARMACOKINETICS OF DICLOXACILLIN IN PATIENTS WITH CYSTIC FIBROSIS Pediatric Research. 8: 358-358. DOI: 10.1203/00006450-197404000-00110 |
0.347 |
|
| 1973 |
Jusko WJ. The Clinical Status of Predictive Pharmacokinetics Ifac Proceedings Volumes. 6: 57-60. DOI: 10.1016/S1474-6670(17)67970-9 |
0.342 |
|
| 1971 |
Jusko WJ, Levy G, Yaffe SJ, Allen JE. Riboflavin absorption in children with biliary obstruction. American Journal of Diseases of Children (1960). 121: 48-52. PMID 5539814 DOI: 10.1001/Archpedi.1971.02100120084011 |
0.486 |
|
| 1970 |
Jusko WJ, Levy G. Pharmacokinetic evidence for saturable renal tubular reabsorption of riboflavin. Journal of Pharmaceutical Sciences. 59: 765-72. PMID 5463652 DOI: 10.1002/Jps.2600590608 |
0.527 |
|
| 1970 |
Jusko WJ, Leonards JR, Levy G. Riboflavin distribution and elimination in two functionally anephric human patients. Journal of Pharmaceutical Sciences. 59: 566-7. PMID 5440692 DOI: 10.1002/Jps.2600590430 |
0.52 |
|
| 1970 |
Jusko WJ, Levy G, Yaffe SJ. Effect of age on intestinal absorption of riboflavin in humans. Journal of Pharmaceutical Sciences. 59: 487-90. PMID 5440675 DOI: 10.1002/Jps.2600590410 |
0.512 |
|
| 1970 |
Jusko WJ, Levy G, Yaffe SJ, Gorodischer R. Effect of probenecid on renal clearance of riboflavin in man. Journal of Pharmaceutical Sciences. 59: 473-7. PMID 5440673 DOI: 10.1002/Jps.2600590407 |
0.493 |
|
| 1969 |
Levy G, Gibaldi M, Jusko WJ. Multicompartment pharmacokinetic models and pharmacologic effects. Journal of Pharmaceutical Sciences. 58: 422-4. PMID 5787438 DOI: 10.1002/Jps.2600580406 |
0.591 |
|
| 1969 |
Jusko WJ, Levy G. Plasma protein binding of riboflavin and riboflavin-5'-phosphate in man. Journal of Pharmaceutical Sciences. 58: 58-62. PMID 5765837 DOI: 10.1002/Jps.2600580110 |
0.512 |
|
| 1967 |
Jusko WJ, Levy G. Effect of probenecid on riboflavin absorption and excretion in man. Journal of Pharmaceutical Sciences. 56: 1145-9. PMID 6049701 DOI: 10.1002/Jps.2600560920 |
0.528 |
|
| 1967 |
Jusko WJ, Levy G. Absorption, metabolism, and excretion of riboflavin-5'-phosphate in man. Journal of Pharmaceutical Sciences. 56: 58-62. PMID 6030496 DOI: 10.1002/Jps.2600560112 |
0.468 |
|
| 1967 |
Levy G, Jusko WJ. Apparent renal tubular secretion of riboflavin in man. Journal of Pharmaceutical Sciences. 55: 1322. PMID 5969798 DOI: 10.1002/Jps.2600551137 |
0.448 |
|
| 1967 |
Levy G, Jusko WJ. Factors affecting the absorption of riboflavin in man. Journal of Pharmaceutical Sciences. 55: 285-9. PMID 5960174 DOI: 10.1002/Jps.2600550305 |
0.517 |
|
| Show low-probability matches. |