Alexandre Prat - Publications

Affiliations: 
Immunology and Microbiology Université de Montréal, Montréal, Canada 
Area:
Immunology, Neuroscience Biology

195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lacoste B, Prat A, Freitas-Andrade M, Gu C. The Blood-Brain Barrier: Composition, Properties, and Roles in Brain Health. Cold Spring Harbor Perspectives in Biology. PMID 38951020 DOI: 10.1101/cshperspect.a041422  0.321
2024 Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, ... ... Prat A, et al. Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology. Nature. PMID 38907058 DOI: 10.1038/s41586-024-07734-0  0.453
2024 Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, ... ... Prat A, et al. Disease-associated astrocyte epigenetic memory promotes CNS pathology. Nature. PMID 38509377 DOI: 10.1038/s41586-024-07187-5  0.527
2024 Pernin F, Cui QL, Mohammadnia A, Fernandes MGF, Hall JA, Srour M, Dudley RWR, Zandee SEJ, Klement W, Prat A, Salapa HE, Levin MC, Moore GRW, Kennedy TE, Vande Velde C, et al. Regulation of stress granule formation in human oligodendrocytes. Nature Communications. 15: 1524. PMID 38374028 DOI: 10.1038/s41467-024-45746-6  0.489
2024 Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, ... ... Prat A, et al. Disease-associated astrocyte epigenetic memory promotes CNS pathology. Biorxiv : the Preprint Server For Biology. PMID 38260616 DOI: 10.1101/2024.01.04.574196  0.537
2023 Zierfuss B, Larochelle C, Prat A. Blood-brain barrier dysfunction in multiple sclerosis: causes, consequences, and potential effects of therapies. The Lancet. Neurology. 23: 95-109. PMID 38101906 DOI: 10.1016/S1474-4422(23)00377-0  0.4
2023 Touil H, Li R, Zuroff L, Moore CS, Healy L, Cignarella F, Piccio L, Ludwin S, Prat A, Gommerman J, Bennett FC, Jacobs D, Benjamins JA, Lisak RP, Antel JP, et al. Cross-talk between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis. Ebiomedicine. 96: 104789. PMID 37703640 DOI: 10.1016/j.ebiom.2023.104789  0.574
2023 Jamann H, Desu HL, Cui QL, Halaweh A, Tastet O, Klement W, Zandee S, Pernin F, Mamane VH, Ouédraogo O, Daigneault A, Sidibé H, Millette F, Peelen E, Dhaeze T, ... ... Prat A, et al. Activated leukocyte cell adhesion molecule on human oligodendrocytes mediates CD4 T cell adhesion. Brain : a Journal of Neurology. PMID 37640028 DOI: 10.1093/brain/awad286  0.602
2023 Fernandes MGF, Mohammadnia A, Pernin F, Schmitz-Gielsdorf LE, Hodgins C, Cui QL, Yaqubi M, Blain M, Hall J, Dudley R, Srour M, Zandee SEJ, Klement W, Prat A, Stratton JA, et al. Mechanisms of metabolic stress induced cell death of human oligodendrocytes: relevance for progressive multiple sclerosis. Acta Neuropathologica Communications. 11: 108. PMID 37408029 DOI: 10.1186/s40478-023-01601-1  0.491
2023 Boudjani H, Fadda G, Dufort G, Antel J, Giacomini P, Levesque-Roy M, Oskoui M, Duquette P, Prat A, Girard M, Rebillard RM, Meijer I, Pinchefsky E, Nguyen CE, Rossignol E, et al. Clinical course, imaging, and pathological features of 45 adult and pediatric cases of myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple Sclerosis and Related Disorders. 76: 104787. PMID 37320939 DOI: 10.1016/j.msard.2023.104787  0.448
2023 Yaqubi M, Groh AMR, Dorion MF, Afanasiev E, Luo JXX, Hashemi H, Sinha S, Kieran NW, Blain M, Cui QL, Biernaskie J, Srour M, Dudley R, Hall JA, Sonnen JA, ... ... Prat A, et al. Analysis of the microglia transcriptome across the human lifespan using single cell RNA sequencing. Journal of Neuroinflammation. 20: 132. PMID 37254100 DOI: 10.1186/s12974-023-02809-7  0.493
2023 Wheeler MA, Clark IC, Lee HG, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, ... ... Prat A, et al. Droplet-based forward genetic screening of astrocyte-microglia cross-talk. Science (New York, N.Y.). 379: 1023-1030. PMID 36893254 DOI: 10.1126/science.abq4822  0.52
2023 Carmena Moratalla A, Carpentier Solorio Y, Lemaître F, Farzam-Kia N, Da Cal S, Guimond JV, Haddad E, Duquette P, Girard JM, Prat A, Larochelle C, Arbour N. Specific alterations in NKG2D T lymphocytes in relapsing-remitting and progressive multiple sclerosis patients. Multiple Sclerosis and Related Disorders. 71: 104542. PMID 36716577 DOI: 10.1016/j.msard.2023.104542  0.337
2023 Clark IC, Wheeler MA, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, Rone JM, Giovannoni F, Charabati M, Akl CF, Aleman DM, ... ... Prat A, et al. Identification of astrocyte regulators by nucleic acid cytometry. Nature. PMID 36599367 DOI: 10.1038/s41586-022-05613-0  0.329
2022 Drake SS, Charabati M, Simas T, Xu YKT, Maes EJP, Shi SS, Antel J, Prat A, Morquette B, Fournier AE. 3-Dimensional Immunostaining and Automated Deep-Learning Based Analysis of Nerve Degeneration. International Journal of Molecular Sciences. 23. PMID 36499143 DOI: 10.3390/ijms232314811  0.478
2022 Fournier AP, Tastet O, Charabati M, Hoornaert C, Bourbonnière L, Klement W, Larouche S, Tea F, Wang YC, Larochelle C, Arbour N, Ragoussis J, Zandee S, Prat A. Single-Cell Transcriptomics Identifies Brain Endothelium Inflammatory Networks in Experimental Autoimmune Encephalomyelitis. Neurology(R) Neuroimmunology & Neuroinflammation. 10. PMID 36446612 DOI: 10.1212/NXI.0000000000200046  0.406
2022 Wiendl H, Schmierer K, Hodgkinson S, Derfuss T, Chan A, Sellebjerg F, Achiron A, Montalban X, Prat A, De Stefano N, Barkhof F, Leocani L, Vermersch P, Chudecka A, Mwape C, et al. Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets: A MAGNIFY-MS Substudy. Neurology(R) Neuroimmunology & Neuroinflammation. 10. PMID 36411081 DOI: 10.1212/NXI.0000000000200048  0.325
2022 Charabati M, Zandee S, Fournier AP, Tastet O, Thai K, Zaminpeyma R, Lécuyer MA, Bourbonnière L, Larouche S, Klement W, Grasmuck C, Tea F, Zierfuss B, Filali-Mouhim A, Moumdjian R, ... ... Prat A, et al. MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes. Brain : a Journal of Neurology. PMID 36319587 DOI: 10.1093/brain/awac389  0.759
2022 Farzam-Kia N, Lemaître F, Carmena Moratalla A, Carpentier Solorio Y, Da Cal S, Jamann H, Klement W, Antel J, Duquette P, Girard JM, Prat A, Larochelle C, Arbour N. GM-CSF-stimulated human macrophages demonstrate enhanced functions contributing to T cell activation. Immunology and Cell Biology. PMID 36260372 DOI: 10.1111/imcb.12600  0.572
2022 Fournier AP, Zandee S, Charabati M, Peelen E, Tastet O, Alvarez JI, Kebir H, Bourbonnière L, Larouche S, Lahav B, Klement W, Tea F, Bouthillier A, Moumdjian R, Cayrol R, ... ... Prat A, et al. CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis. Neurology(R) Neuroimmunology & Neuroinflammation. 9. PMID 36241608 DOI: 10.1212/NXI.0000000000200022  0.73
2022 Hermans D, Houben E, Baeten P, Slaets H, Janssens K, Hoeks C, Hosseinkhani B, Duran G, Bormans S, Gowing E, Hoornaert C, Beckers L, Fung WK, Schroten H, Ishikawa H, ... ... Prat A, et al. Oncostatin M triggers brain inflammation by compromising blood-brain barrier integrity. Acta Neuropathologica. 144: 259-281. PMID 35666306 DOI: 10.1007/s00401-022-02445-0  0.446
2022 Pernin F, Luo J, Cui QL, Blain M, Fernandes MGF, Yaqubi M, Srour M, Hall J, Dudley R, Jamann H, Larochelle C, Zandee SEJ, Prat A, Stratton JA, Kennedy TE, et al. Diverse injury responses of human oligodendrocyte to mediators implicated in multiple sclerosis. Brain : a Journal of Neurology. PMID 35202462 DOI: 10.1093/brain/awac075  0.513
2022 Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, ... ... Prat A, et al. DICAM promotes T17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation. Science Translational Medicine. 14: eabj0473. PMID 34985970 DOI: 10.1126/scitranslmed.abj0473  0.798
2021 Carmena Moratalla A, Carpentier Solorio Y, Lemaitre F, Farzam-Kia N, Levert A, Zandee SEJ, Lahav B, Guimond JV, Haddad E, Girard M, Duquette P, Larochelle C, Prat A, Arbour N. Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8 T-Cell Behaviors. Neurology(R) Neuroimmunology & Neuroinflammation. 9. PMID 34873031 DOI: 10.1212/NXI.0000000000001119  0.323
2021 Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, Linnerbauer M, Sanmarco LM, Guo L, Blain M, Zandee SEJ, Chao CC, Batterman KV, Schwabenland M, Lotfy P, Tejeda-Velarde A, ... ... Prat A, et al. Barcoded viral tracing of single-cell interactions in central nervous system inflammation. Science (New York, N.Y.). 372. PMID 33888612 DOI: 10.1126/science.abf1230  0.568
2021 Sanmarco LM, Wheeler MA, Gutiérrez-Vázquez C, Polonio CM, Linnerbauer M, Pinho-Ribeiro FA, Li Z, Giovannoni F, Batterman KV, Scalisi G, Zandee SEJ, Heck ES, Alsuwailm M, Rosene DL, Becher B, ... ... Prat A, et al. Gut-licensed IFNγ NK cells drive LAMP1TRAIL anti-inflammatory astrocytes. Nature. PMID 33408417 DOI: 10.1038/s41586-020-03116-4  0.312
2020 Broux B, Zandee S, Gowing E, Charabati M, Lécuyer MA, Tastet O, Hachehouche L, Bourbonnière L, Ouimet JP, Lemaitre F, Larouche S, Cayrol R, Bouthillier A, Moumdjian R, Lahav B, ... ... Prat A, et al. Interleukin-26, preferentially produced by T17 lymphocytes, regulates CNS barrier function. Neurology(R) Neuroimmunology & Neuroinflammation. 7. PMID 32788322 DOI: 10.1212/Nxi.0000000000000870  0.743
2020 Lizak N, Malpas CB, Sharmin S, Havrdova EK, Horakova D, Izquierdo G, Eichau S, Lugaresi A, Duquette P, Girard M, Prat A, Larochelle C, Trojano M, Grand'Maison F, Grammond P, et al. Association of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis. Jama Neurology. PMID 32716480 DOI: 10.1001/Jamaneurol.2020.2453  0.321
2020 Le M, Malpas C, Sharmin S, Horáková D, Havrdova E, Trojano M, Izquierdo G, Eichau S, Ozakbas S, Lugaresi A, Prat A, Girard M, Duquette P, Larochelle C, Alroughani R, et al. Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520926955. PMID 32538713 DOI: 10.1177/1352458520926955  0.302
2020 Ayrignac X, Larochelle C, Keezer M, Roger E, Poirier J, Lahav B, Girard M, Prat A, Duquette P. Frailty in ageing persons with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520923945. PMID 32458728 DOI: 10.1177/1352458520923945  0.315
2020 Ayrignac X, Letourneau-Guillon L, Carra-Dallière C, Duquette P, Girard M, Poirier J, Lahav B, Larochelle C, Prat A. From Baló's concentric sclerosis to multiple sclerosis: a series of 6 patients. Multiple Sclerosis and Related Disorders. 42: 102078. PMID 32408148 DOI: 10.1016/J.Msard.2020.102078  0.344
2020 Masaki K, Sonobe Y, Ghadge G, Pytel P, Lépine P, Pernin F, Cui QL, Antel JP, Zandee S, Prat A, Roos RP. RNA-binding protein altered expression and mislocalization in MS. Neurology(R) Neuroimmunology & Neuroinflammation. 7. PMID 32217641 DOI: 10.1212/Nxi.0000000000000704  0.493
2020 Wheeler MA, Clark IC, Tjon EC, Li Z, Zandee SEJ, Couturier CP, Watson BR, Scalisi G, Alkwai S, Rothhammer V, Rotem A, Heyman JA, Thaploo S, Sanmarco LM, Ragoussis J, ... ... Prat A, et al. MAFG-driven astrocytes promote CNS inflammation. Nature. PMID 32051591 DOI: 10.1038/S41586-020-1999-0  0.596
2020 Chitnis T, Prat A. A roadmap to precision medicine for multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519881558. PMID 31965904 DOI: 10.1177/1352458519881558  0.348
2020 Antel JP, Becher B, Ludwin SK, Prat A, Quintana FJ. Glial Cells as Regulators of Neuroimmune Interactions in the Central Nervous System. Journal of Immunology (Baltimore, Md. : 1950). 204: 251-255. PMID 31907266 DOI: 10.4049/Jimmunol.1900908  0.562
2019 Bernard-Patrzynski F, Lécuyer MA, Puscas I, Boukhatem I, Charabati M, Bourbonnière L, Ramassamy C, Leclair G, Prat A, Roullin VG. Isolation of endothelial cells, pericytes and astrocytes from mouse brain. Plos One. 14: e0226302. PMID 31851695 DOI: 10.1371/Journal.Pone.0226302  0.426
2019 Charabati M, Rabanel JM, Ramassamy C, Prat A. Overcoming the Brain Barriers: From Immune Cells to Nanoparticles. Trends in Pharmacological Sciences. PMID 31839374 DOI: 10.1016/J.Tips.2019.11.001  0.385
2019 Chao CC, Gutiérrez-Vázquez C, Rothhammer V, Mayo L, Wheeler MA, Tjon EC, Zandee SEJ, Blain M, de Lima KA, Takenaka MC, Avila-Pacheco J, Hewson P, Liu L, Sanmarco LM, Borucki DM, ... ... Prat A, et al. Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. Cell. PMID 31813625 DOI: 10.1016/j.cell.2019.11.016  0.506
2019 Michel L, Grasmuck C, Charabati M, Lécuyer MA, Zandee S, Dhaeze T, Alvarez JI, Li R, Larouche S, Bourbonnière L, Moumdjian R, Bouthillier A, Lahav B, Duquette P, Bar-Or A, ... ... Prat A, et al. Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers. Science Translational Medicine. 11. PMID 31723036 DOI: 10.1126/Scitranslmed.Aaw0475  0.47
2019 Puscas I, Bernard-Patrzynski F, Jutras M, Lécuyer MA, Bourbonnière L, Prat A, Leclair G, Roullin VG. IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening. Pharmaceutics. 11. PMID 31717321 DOI: 10.3390/Pharmaceutics11110587  0.32
2019 Fambiatos A, Jokubaitis V, Horakova D, Kubala Havrdova E, Trojano M, Prat A, Girard M, Duquette P, Lugaresi A, Izquierdo G, Grand'Maison F, Grammond P, Sola P, Ferraro D, Alroughani R, et al. Risk of secondary progressive multiple sclerosis: A longitudinal study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519868990. PMID 31397221 DOI: 10.1177/1352458519868990  0.3
2019 Ramaglia V, Sheikh-Mohamed S, Legg K, Park C, Rojas OL, Zandee S, Fu F, Ornatsky O, Swanson EC, Pitt D, Prat A, McKee TD, Gommerman JL. Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry. Elife. 8. PMID 31368890 DOI: 10.7554/Elife.48051  0.432
2019 Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, ... ... Prat A, et al. Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39. Nature Neuroscience. PMID 31197266 DOI: 10.1038/S41593-019-0446-8  0.52
2019 Ayrignac X, Bilodeau PA, Prat A, Girard M, Labauge P, Le Lorier J, Larochelle C, Duquette P. Assessing the risk of multiple sclerosis disease-modifying therapies. Expert Review of Neurotherapeutics. PMID 31195842 DOI: 10.1080/14737175.2019.1627201  0.302
2019 Dhaeze T, Lachance C, Tremblay L, Grasmuck C, Bourbonnière L, Larouche S, Saint-Laurent O, Lécuyer MA, Rébillard RM, Zandee S, Prat A. Sex-dependent factors encoded in the immune compartment dictate relapsing or progressive phenotype in demyelinating disease. Jci Insight. 4. PMID 30895941 DOI: 10.1172/Jci.Insight.124885  0.364
2019 Derada Troletti C, Fontijn RD, Gowing E, Charabati M, van Het Hof B, Didouh I, van der Pol SMA, Geerts D, Prat A, van Horssen J, Kooij G, de Vries HE. Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology. Cell Death & Disease. 10: 45. PMID 30718504 DOI: 10.1038/S41419-018-1294-2  0.476
2019 Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutiérrez-Vázquez C, Prat A, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. PMID 30661753 DOI: 10.1016/J.Cell.2018.12.012  0.565
2019 Kalincik T, Kubala Havrdova E, Horakova D, Izquierdo G, Prat A, Girard M, Duquette P, Grammond P, Onofrj M, Lugaresi A, Ozakbas S, Kappos L, Kuhle J, Terzi M, Lechner-Scott J, et al. Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 30636699 DOI: 10.1136/Jnnp-2018-319831  0.344
2019 Dhaeze T, Tremblay L, Lachance C, Peelen E, Zandee S, Grasmuck C, Bourbonnière L, Larouche S, Ayrignac X, Rébillard RM, Poirier J, Lahav B, Duquette P, Girard M, Moumdjian R, ... ... Prat A, et al. CD70 defines a subset of proinflammatory and CNS-pathogenic T1/T17 lymphocytes and is overexpressed in multiple sclerosis. Cellular & Molecular Immunology. PMID 30635649 DOI: 10.1038/S41423-018-0198-5  0.391
2019 Ramaglia V, Sheikh-Mohamed S, Legg K, Park C, Rojas OL, Zandee S, Fu F, Ornatsky O, Swanson EC, Pitt D, Prat A, McKee TD, Gommerman JL. Author response: Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry Elife. DOI: 10.7554/Elife.48051.028  0.347
2018 Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, ... ... Prat A, et al. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. PMID 30612739 DOI: 10.1016/J.Cell.2018.11.035  0.386
2018 Hughes J, Jokubaitis V, Lugaresi A, Hupperts R, Izquierdo G, Prat A, Girard M, Duquette P, Grand'Maison F, Grammond P, Sola P, Ferraro D, Ramo-Tello C, Trojano M, Slee M, et al. Association of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis. Jama Neurology. PMID 30083762 DOI: 10.1001/Jamaneurol.2018.2109  0.38
2018 Serafini B, Zandee S, Rosicarelli B, Scorsi E, Veroni C, Larochelle C, D'Alfonso S, Prat A, Aloisi F. Epstein-Barr virus-associated immune reconstitution inflammatory syndrome as possible cause of fulminant multiple sclerosis relapse after natalizumab interruption. Journal of Neuroimmunology. 319: 9-12. PMID 29685294 DOI: 10.1016/J.Jneuroim.2018.03.011  0.466
2018 Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, Fawaz L, Moore CS, Prat A, Gommerman J, Antel JP, Itoyama Y, Nakashima I, Bar-Or A. Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis. Journal of Neuroinflammation. 15: 114. PMID 29673365 DOI: 10.1186/S12974-018-1136-2  0.622
2018 Kebir H, Carmant L, Fontaine F, Béland K, Bosoi CM, Sanon NT, Alvarez JI, Desgent S, Pittet CL, Hébert D, Langlois MJ, Rébillard RM, Nguyen DK, Cieuta-Walti C, Holmes GL, ... ... Prat A, et al. Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis. The Journal of Clinical Investigation. PMID 29629902 DOI: 10.1172/Jci97098  0.391
2018 Larochelle C, Uphaus T, Broux B, Gowing E, Paterka M, Michel L, Dudvarski Stankovic N, Bicker F, Lemaître F, Prat A, Schmidt MHH, Zipp F. EGFL7 reduces CNS inflammation in mouse. Nature Communications. 9: 819. PMID 29483510 DOI: 10.1038/S41467-018-03186-Z  0.517
2018 Paré A, Mailhot B, Lévesque SA, Juzwik C, Ignatius Arokia Doss PM, Lécuyer MA, Prat A, Rangachari M, Fournier A, Lacroix S. IL-1β enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358392 DOI: 10.1073/Pnas.1714948115  0.398
2018 de Stefano N, Achiron A, Barkhof F, Chan A, Derfuss T, Hodgkinson S, Leocani L, Montalban X, Prat A, Schmierer K, Sellebjerg F, Vermersch P, Wiendl H, Keller B, Roy S. THUR 174 The magnify-ms study: mavenclad® tablets in active rms Journal of Neurology, Neurosurgery & Psychiatry. 89: A23.1-A23. DOI: 10.1136/Jnnp-2018-Abn.81  0.344
2018 Jhuti G, Freitas R, Bennett I, Butzkueven H, Izquierdo G, Eichau S, Havrdova E, Horakova D, Duquette P, Prat A, Girard M, Grand'Maison F, Hupperts R, Lugaresi A, Onofrj M, et al. PND18 - PROGRESSION OF DISABILITY IN PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS: A RETROSPECTIVE COHORT STUDY USING DATA FROM THE MSBASE REGISTRY AND A CONTEXTUALISATION WITH AN EXISTING NATURAL HISTORY DATASET Value in Health. 21: S332. DOI: 10.1016/J.Jval.2018.09.1985  0.312
2017 Troletti CD, Lopes Pinheiro MA, Charabati M, Gowing E, van Het Hof B, der Pol SMAV, Geerts D, Prat A, Fontijn RD, Unger WW, de Vries HE. Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner. Brain, Behavior, and Immunity. PMID 29289661 DOI: 10.1016/J.Bbi.2017.12.016  0.402
2017 Ifergan I, Davidson TS, Kebir H, Xu D, Palacios-Macapagal D, Cann J, Rodgers JM, Hunter ZN, Pittet CL, Beddow S, Jones CA, Prat A, Sleeman MA, Miller SD. Targeting the GM-CSF receptor for the treatment of CNS autoimmunity. Journal of Autoimmunity. PMID 28641926 DOI: 10.1016/J.Jaut.2017.06.005  0.705
2017 Signori A, Izquierdo G, Lugaresi A, Hupperts R, Grand'Maison F, Sola P, Horakova D, Havrdova E, Prat A, Girard M, Duquette P, Boz C, Grammond P, Terzi M, Singhal B, et al. Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517703800. PMID 28382837 DOI: 10.1177/1352458517703800  0.32
2017 Li R, Rezk A, Li H, Gommerman JL, Prat A, Bar-Or A. Antibody-Independent Function of Human B Cells Contributes to Antifungal T Cell Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 28275140 DOI: 10.4049/Jimmunol.1601572  0.406
2017 Lühder F, Kebir H, Odoardi F, Litke T, Sonneck M, Alvarez JI, Winchenbach J, Eckert N, Hayardeny L, Sorani E, Lodygin D, Flügel A, Prat A. Laquinimod enhances central nervous system barrier functions. Neurobiology of Disease. PMID 28235673 DOI: 10.1016/J.Nbd.2017.02.002  0.53
2017 Kalincik T, Brown JW, Robertson N, Willis M, Scolding N, Rice CM, Wilkins A, Pearson O, Ziemssen T, Hutchinson M, McGuigan C, Jokubaitis V, Spelman T, Horakova D, Havrdova E, ... ... Prat A, et al. Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study. The Lancet. Neurology. PMID 28209331 DOI: 10.1016/S1474-4422(17)30007-8  0.317
2017 Lécuyer MA, Saint-Laurent O, Bourbonnière L, Larouche S, Larochelle C, Michel L, Charabati M, Abadier M, Zandee S, Haghayegh Jahromi N, Gowing E, Pittet C, Lyck R, Engelhardt B, Prat A. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28069965 DOI: 10.1073/Pnas.1614336114  0.474
2016 Lyck R, Lécuyer MA, Abadier M, Wyss CB, Matti C, Rosito M, Enzmann G, Zeis T, Michel L, García Martín AB, Sallusto F, Gosselet F, Deutsch U, Weiner JA, Schaeren-Wiemers N, ... Prat A, et al. ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X16678639. PMID 28273717 DOI: 10.1177/0271678X16678639  0.412
2016 Kuhlmann T, Ludwin S, Prat A, Antel J, Brück W, Lassmann H. An updated histological classification system for multiple sclerosis lesions. Acta Neuropathologica. PMID 27988845 DOI: 10.1007/S00401-016-1653-Y  0.556
2016 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, ... ... Prat A, et al. Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. 17: 1479. PMID 27849203 DOI: 10.1038/ni1216-1479c  0.432
2016 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, ... ... Prat A, et al. USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. PMID 27721430 DOI: 10.1038/Ni.3581  0.586
2016 Lizak N, Lugaresi A, Alroughani R, Lechner-Scott J, Slee M, Havrdova E, Horakova D, Trojano M, Izquierdo G, Duquette P, Girard M, Prat A, Grammond P, Hupperts R, Grand'Maison F, et al. Highly active immunomodulatory therapy ameliorates accumulation of disability in moderately advanced and advanced multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27683916 DOI: 10.1136/Jnnp-2016-313976  0.32
2016 Lorscheider J, Buzzard K, Jokubaitis V, Spelman T, Havrdova E, Horakova D, Trojano M, Izquierdo G, Girard M, Duquette P, Prat A, Lugaresi A, Grand'Maison F, Grammond P, Hupperts R, et al. Defining secondary progressive multiple sclerosis. Brain : a Journal of Neurology. PMID 27401521 DOI: 10.1093/Brain/Aww173  0.324
2016 Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain : a Journal of Neurology. PMID 27246324 DOI: 10.1093/Brain/Aww113  0.508
2016 Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, ... ... Prat A, et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nature Medicine. PMID 27158906 DOI: 10.1038/Nm.4106  0.599
2016 Jokubaitis VG, Spelman T, Kalincik T, Lorscheider J, Havrdova E, Horakova D, Duquette P, Girard M, Prat A, Izquierdo G, Grammond P, Van Pesch V, Pucci E, Grand'Maison F, Hupperts R, et al. Predictors of long-term disability accrual in relapse-onset multiple sclerosis. Annals of Neurology. PMID 27145331 DOI: 10.1002/Ana.24682  0.311
2016 Lévesque SA, Paré A, Mailhot B, Bellver-Landete V, Kébir H, Lécuyer MA, Alvarez JI, Prat A, Vaccari JP, Keane RW, Lacroix S. Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice. The Journal of Experimental Medicine. PMID 27139491 DOI: 10.1084/Jem.20151437  0.326
2016 Stewart T, Spelman T, Havrdova E, Horakova D, Trojano M, Izquierdo G, Duquette P, Girard M, Prat A, Lugaresi A, Grand'Maison F, Grammond P, Sola P, Shaygannejad V, Hupperts R, et al. Contribution of different relapse phenotypes to disability in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 27055805 DOI: 10.1177/1352458516643392  0.351
2016 Luo H, Broux B, Wang X, Hu Y, Ghannam S, Jin W, Larochelle C, Prat A, Wu J. EphrinB1 and EphrinB2 regulate T cell chemotaxis and migration in experimental autoimmune encephalomyelitis and multiple sclerosis. Neurobiology of Disease. PMID 27039370 DOI: 10.1016/J.Nbd.2016.03.013  0.494
2016 Larochelle C, Metz I, Lécuyer MA, Terouz S, Roger M, Arbour N, Brück W, Prat A. Immunological and pathological characterization of fatal rebound MS activity following natalizumab withdrawal. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 27037182 DOI: 10.1177/1352458516641775  0.386
2016 Larochelle C, Uphaus T, Prat A, Zipp F. Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology? Trends in Neurosciences. PMID 26987259 DOI: 10.1016/J.Tins.2016.02.001  0.337
2016 Michel L, Prat A. One more role for the gut: microbiota and blood brain barrier. Annals of Translational Medicine. 4: 15. PMID 26855951 DOI: 10.3978/J.Issn.2305-5839.2015.10.16  0.37
2016 Lécuyer MA, Kebir H, Prat A. Glial influences on BBB functions and molecular players in immune cell trafficking. Biochimica Et Biophysica Acta. 1862: 472-82. PMID 26454208 DOI: 10.1016/J.Bbadis.2015.10.004  0.464
2016 Vadboncoeur J, Biernacki K, Prat A, Jaworski L. Multiple sclerosis-associated uveitis Expert Review of Ophthalmology. 12: 57-67. DOI: 10.1080/17469899.2017.1264875  0.345
2015 Pikor NB, Prat A, Bar-Or A, Gommerman JL. Meningeal Tertiary Lymphoid Tissues and Multiple Sclerosis: A Gathering Place for Diverse Types of Immune Cells during CNS Autoimmunity. Frontiers in Immunology. 6: 657. PMID 26793195 DOI: 10.3389/Fimmu.2015.00657  0.437
2015 Li R, Rezk A, Healy LM, Muirhead G, Prat A, Gommerman JL, Bar-Or A. Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis. Frontiers in Immunology. 6: 626. PMID 26779181 DOI: 10.3389/Fimmu.2015.00626  0.438
2015 Alvarez JI, Kébir H, Cheslow L, Chabarati M, Larochelle C, Prat A. JAML mediates monocyte and CD8 T cell migration across the brain endothelium. Annals of Clinical and Translational Neurology. 2: 1032-7. PMID 26734656 DOI: 10.1002/Acn3.255  0.524
2015 Michel L, Touil H, Pikor NB, Gommerman JL, Prat A, Bar-Or A. B Cells in the Multiple Sclerosis Central Nervous System: Trafficking and Contribution to CNS-Compartmentalized Inflammation. Frontiers in Immunology. 6: 636. PMID 26732544 DOI: 10.3389/Fimmu.2015.00636  0.443
2015 Pikor NB, Astarita JL, Summers-Deluca L, Galicia G, Qu J, Ward LA, Armstrong S, Dominguez CX, Malhotra D, Heiden B, Kay R, Castanov V, Touil H, Boon L, O'Connor P, ... ... Prat A, et al. Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation. Immunity. 43: 1160-73. PMID 26682987 DOI: 10.1016/J.Immuni.2015.11.010  0.469
2015 Sénécal V, Deblois G, Beauseigle D, Schneider R, Brandenburg J, Newcombe J, Moore CS, Prat A, Antel J, Arbour N. Production of IL-27 in multiple sclerosis lesions by astrocytes and myeloid cells: Modulation of local immune responses. Glia. PMID 26649511 DOI: 10.1002/Glia.22948  0.606
2015 Li R, Rezk A, Miyazaki Y, Hilgenberg E, Touil H, Shen P, Moore CS, Michel L, Althekair F, Rajasekharan S, Gommerman JL, Prat A, Fillatreau S, Bar-Or A. Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy. Science Translational Medicine. 7: 310ra166. PMID 26491076 DOI: 10.1126/Scitranslmed.Aab4176  0.417
2015 Broux B, Gowing E, Prat A. Glial regulation of the blood-brain barrier in health and disease. Seminars in Immunopathology. 37: 577-90. PMID 26245144 DOI: 10.1007/S00281-015-0516-2  0.42
2015 Podjaski C, Alvarez JI, Bourbonniere L, Larouche S, Terouz S, Bin JM, Lécuyer MA, Saint-Laurent O, Larochelle C, Darlington PJ, Arbour N, Antel JP, Kennedy TE, Prat A. Netrin 1 regulates blood-brain barrier function and neuroinflammation. Brain : a Journal of Neurology. 138: 1598-612. PMID 25903786 DOI: 10.1093/Brain/Awv092  0.632
2015 Larochelle C, Lécuyer MA, Alvarez JI, Charabati M, Saint-Laurent O, Ghannam S, Kebir H, Flanagan K, Yednock T, Duquette P, Arbour N, Prat A. Melanoma cell adhesion molecule-positive CD8 T lymphocytes mediate central nervous system inflammation. Annals of Neurology. 78: 39-53. PMID 25869475 DOI: 10.1002/Ana.24415  0.487
2015 Legroux L, Pittet CL, Beauseigle D, Deblois G, Prat A, Arbour N. An optimized method to process mouse CNS to simultaneously analyze neural cells and leukocytes by flow cytometry. Journal of Neuroscience Methods. 247: 23-31. PMID 25819540 DOI: 10.1016/J.Jneumeth.2015.03.021  0.308
2015 Michel L, Larochelle C, Prat A. Update on treatments in multiple sclerosis. Presse MéDicale (Paris, France : 1983). 44: e137-51. PMID 25813102 DOI: 10.1016/J.Lpm.2015.02.008  0.32
2015 Daneman R, Prat A. The blood-brain barrier. Cold Spring Harbor Perspectives in Biology. 7: a020412. PMID 25561720 DOI: 10.1101/Cshperspect.A020412  0.428
2015 Alvarez JI, Saint-Laurent O, Godschalk A, Terouz S, Briels C, Larouche S, Bourbonnière L, Larochelle C, Prat A. Focal disturbances in the blood-brain barrier are associated with formation of neuroinflammatory lesions. Neurobiology of Disease. 74: 14-24. PMID 25448765 DOI: 10.1016/J.Nbd.2014.09.016  0.48
2014 Mayo L, Trauger SA, Blain M, Nadeau M, Patel B, Alvarez JI, Mascanfroni ID, Yeste A, Kivisäkk P, Kallas K, Ellezam B, Bakshi R, Prat A, Antel JP, Weiner HL, et al. Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation. Nature Medicine. 20: 1147-56. PMID 25216636 DOI: 10.1038/Nm.3681  0.624
2014 Miyazaki Y, Li R, Rezk A, Misirliyan H, Moore C, Farooqi N, Solis M, Goiry LG, de Faria Junior O, Dang VD, Colman D, Dhaunchak AS, Antel J, Gommerman J, Prat A, et al. A novel microRNA-132-surtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis. Plos One. 9: e105421. PMID 25136908 DOI: 10.1371/Journal.Pone.0105421  0.595
2014 Aubé B, Lévesque SA, Paré A, Chamma É, Kébir H, Gorina R, Lécuyer MA, Alvarez JI, De Koninck Y, Engelhardt B, Prat A, Côté D, Lacroix S. Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases Journal of Immunology. 193: 2438-2454. PMID 25049355 DOI: 10.4049/Jimmunol.1400401  0.452
2014 Touil H, Moore CS, Li R, Kobert A, Healy L, Prat A, Gommerman JL, Antel J, Bar-or A. Human B cell and glial cell interactions: Implications to the compartmentalized CNS inflammation of multiple sclerosis (MS) Journal of Neuroimmunology. 275: 176-177. DOI: 10.1016/J.Jneuroim.2014.08.474  0.441
2014 Larochelle C, Lécuyer M, Alvarez JI, Charabati M, Kebir H, Saint-laurent O, Cayrol R, Duquette P, Flanagan K, Arbour N, Prat A. MCAM identifies inflammatory encephalitogenic CD8 T lymphocytes presenting a high cytotoxic capacity Journal of Neuroimmunology. 275: 159. DOI: 10.1016/J.Jneuroim.2014.08.426  0.694
2014 Katayama T, Nakano A, Ifergan I, Kebir H, Lécuyer M, Larochelle C, Alvarez JI, Prat A. Functional analyses of transmigrated monocyte-derived CD123+ dendritic cells across the inflamed blood–brain barrier endothelium Journal of Neuroimmunology. 275: 155. DOI: 10.1016/J.Jneuroim.2014.08.416  0.685
2014 Broux B, Hongyu L, Ghannam S, Larochelle C, Jin W, Hu Y, Wang X, Wang Y, Wu J, Prat A. Ephrin B1 and B2 are essential for the pathogenicity and migration capacity of TH17 cells in EAE and MS Journal of Neuroimmunology. 275: 140. DOI: 10.1016/J.Jneuroim.2014.08.376  0.358
2014 Gowing E, Gendron S, Lécuyer M, Terouz S, Prat A. Characterizing the role of integrin alpha8 in mediating CD4+ T lymphocyte migration across the blood–brain barrier in multiple sclerosis Journal of Neuroimmunology. 275: 99-100. DOI: 10.1016/J.Jneuroim.2014.08.267  0.404
2014 Broux B, Hachehouche L, Kébir H, Terouz S, Bourbonniere L, Prat A. The novel TH17-associated cytokine IL-26 mediates BBB breakdown and neuroinflammation Journal of Neuroimmunology. 275: 27-28. DOI: 10.1016/J.Jneuroim.2014.08.075  0.316
2014 Alvarez JI, Podjaski C, Bourbonniere L, Larouche S, Terouz S, Lecuyer M, Hachehouche L, Nakano A, Sabbagh M, Saint-laurent O, Larochelle C, Bin J, Darlington P, Arbour N, Antel J, ... ... Prat A, et al. Netrin-1 regulates blood–brain barrier function and CNS inflammation Journal of Neuroimmunology. 275: 26-27. DOI: 10.1016/J.Jneuroim.2014.08.072  0.562
2014 Michel L, Alvarez JI, Kebir H, Bourbonnière L, Poirier J, Duquette P, Bar-or A, Gommerman J, Prat A. The CNS barriers differentially regulate the migration of B cells Journal of Neuroimmunology. 275: 11. DOI: 10.1016/J.Jneuroim.2014.08.034  0.345
2014 Li R, Fillatreau S, Gommerman J, Prat A, Bar-or A. ‘Cytokine defined’ B cell subsets in multiple sclerosis Journal of Neuroimmunology. 275: 10. DOI: 10.1016/J.Jneuroim.2014.08.032  0.366
2013 Schwartz M, Kipnis J, Rivest S, Prat A. How do immune cells support and shape the brain in health, disease, and aging? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17587-96. PMID 24198349 DOI: 10.1523/Jneurosci.3241-13.2013  0.449
2013 Alvarez JI, Katayama T, Prat A. Glial influence on the blood brain barrier. Glia. 61: 1939-58. PMID 24123158 DOI: 10.1002/Glia.22575  0.456
2013 Pickles S, Cadieux-Dion M, Alvarez JI, Lécuyer MA, Peyrard SL, Destroismaisons L, St-Onge L, Terouz S, Cossette P, Prat A, Vande Velde C. Endo-MitoEGFP mice: a novel transgenic mouse with fluorescently marked mitochondria in microvascular endothelial cells. Plos One. 8: e74603. PMID 24019971 DOI: 10.1371/Journal.Pone.0074603  0.333
2013 Agrawal SM, Williamson J, Sharma R, Kebir H, Patel K, Prat A, Yong VW. Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis. Brain : a Journal of Neurology. 136: 1760-77. PMID 23687119 DOI: 10.1093/Brain/Awt093  0.401
2013 Freedman MS, Selchen D, Arnold DL, Prat A, Banwell B, Yeung M, Morgenthau D, Lapierre Y. Treatment optimization in MS: Canadian MS Working Group updated recommendations. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 40: 307-23. PMID 23603165 DOI: 10.1017/S0317167100014244  0.312
2013 Reijerkerk A, Lopez-Ramirez MA, van Het Hof B, Drexhage JA, Kamphuis WW, Kooij G, Vos JB, van der Pouw Kraan TC, van Zonneveld AJ, Horrevoets AJ, Prat A, Romero IA, de Vries HE. MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6857-63. PMID 23595744 DOI: 10.1523/Jneurosci.3965-12.2013  0.471
2013 Darlington PJ, Touil T, Doucet JS, Gaucher D, Zeidan J, Gauchat D, Corsini R, Kim HJ, Duddy M, Jalili F, Arbour N, Kebir H, Chen J, Arnold DL, Bowman M, ... ... Prat A, et al. Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation. Annals of Neurology. 73: 341-54. PMID 23463494 DOI: 10.1002/Ana.23784  0.569
2013 Zaguia F, Saikali P, Ludwin S, Newcombe J, Beauseigle D, McCrea E, Duquette P, Prat A, Antel JP, Arbour N. Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 190: 2510-8. PMID 23396942 DOI: 10.4049/Jimmunol.1202725  0.634
2013 Mizee MR, Wooldrik D, Lakeman KA, van het Hof B, Drexhage JA, Geerts D, Bugiani M, Aronica E, Mebius RE, Prat A, de Vries HE, Reijerkerk A. Retinoic acid induces blood-brain barrier development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1660-71. PMID 23345238 DOI: 10.1523/Jneurosci.1338-12.2013  0.395
2013 Muldoon LL, Alvarez JI, Begley DJ, Boado RJ, Del Zoppo GJ, Doolittle ND, Engelhardt B, Hallenbeck JM, Lonser RR, Ohlfest JR, Prat A, Scarpa M, Smeyne RJ, Drewes LR, Neuwelt EA. Immunologic privilege in the central nervous system and the blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 13-21. PMID 23072749 DOI: 10.1038/Jcbfm.2012.153  0.441
2013 Schneider R, Beauseigle D, Duquette P, Prat A, Johnson H, Arbour N. Interferon-beta up-regulates suppressor of cytokine signaling 1 in T cells of multiple sclerosis patients Journal of the Neurological Sciences. 333: e401. DOI: 10.1016/J.Jns.2013.07.1451  0.363
2012 Larochelle C, Cayrol R, Kebir H, Alvarez JI, Lécuyer MA, Ifergan I, Viel É, Bourbonnière L, Beauseigle D, Terouz S, Hachehouche L, Gendron S, Poirier J, Jobin C, Duquette P, ... ... Prat A, et al. Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system. Brain : a Journal of Neurology. 135: 2906-24. PMID 22975388 DOI: 10.1093/Brain/Aws212  0.833
2012 Flanagan K, Fitzgerald K, Baker J, Regnstrom K, Gardai S, Bard F, Mocci S, Seto P, You M, Larochelle C, Prat A, Chow S, Li L, Vandevert C, Zago W, et al. Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS. Plos One. 7: e40443. PMID 22792325 DOI: 10.1371/Journal.Pone.0040443  0.453
2012 Zhang MA, Rego D, Moshkova M, Kebir H, Chruscinski A, Nguyen H, Akkermann R, Stanczyk FZ, Prat A, Steinman L, Dunn SE. Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way. Proceedings of the National Academy of Sciences of the United States of America. 109: 9505-10. PMID 22647601 DOI: 10.1073/Pnas.1118458109  0.404
2012 Berard JL, Zarruk JG, Arbour N, Prat A, Yong VW, Jacques FH, Akira S, David S. Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis. Glia. 60: 1145-59. PMID 22499213 DOI: 10.1002/Glia.22342  0.446
2012 Larochelle C, Cayrol R, Kebir H, Lecuyer M, Alvarez J, Arbour N, Prat A. MCAM Identifies Encephalitogenic TH17 Lymphocytes and Promotes Their Recruitment to the CNS (SC02.001) Neurology. 78: SC02.001-SC02.001. DOI: 10.1212/Wnl.78.1_Meetingabstracts.Sc02.001  0.778
2012 Kebir H, Alvarez JI, Prat A. Effects of Laquinimod on the Human Blood-Brain Barrier (P02.118) Neurology. 78: P02.118-P02.118. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.118  0.358
2011 Ifergan I, Kebir H, Terouz S, Alvarez JI, Lécuyer MA, Gendron S, Bourbonnière L, Dunay IR, Bouthillier A, Moumdjian R, Fontana A, Haqqani A, Klopstein A, Prinz M, López-Vales R, ... ... Prat A, et al. Role of Ninjurin-1 in the migration of myeloid cells to central nervous system inflammatory lesions. Annals of Neurology. 70: 751-63. PMID 22162058 DOI: 10.1002/Ana.22519  0.763
2011 Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonnière L, Bernard M, van Horssen J, de Vries HE, Charron F, Prat A. The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science (New York, N.Y.). 334: 1727-31. PMID 22144466 DOI: 10.1126/Science.1206936  0.726
2011 Pittet CL, Newcombe J, Prat A, Arbour N. Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis. Journal of Neuroinflammation. 8: 155. PMID 22067141 DOI: 10.1186/1742-2094-8-155  0.392
2011 Ifergan I, Kebir H, Alvarez JI, Marceau G, Bernard M, Bourbonnière L, Poirier J, Duquette P, Talbot PJ, Arbour N, Prat A. Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin. Brain : a Journal of Neurology. 134: 3560-77. PMID 22058139 DOI: 10.1093/Brain/Awr268  0.729
2011 Schneider R, Mohebiany AN, Ifergan I, Beauseigle D, Duquette P, Prat A, Arbour N. B cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients. Journal of Immunology (Baltimore, Md. : 1950). 187: 4119-28. PMID 21911607 DOI: 10.4049/Jimmunol.1100885  0.715
2011 Larochelle C, Alvarez JI, Prat A. How do immune cells overcome the blood-brain barrier in multiple sclerosis? Febs Letters. 585: 3770-80. PMID 21550344 DOI: 10.1016/J.Febslet.2011.04.066  0.516
2011 Prat A. Special issue on molecular basis of multiple sclerosis. Biochimica Et Biophysica Acta. 1812: 131. PMID 21168062 DOI: 10.1016/J.Bbadis.2010.12.003  0.322
2011 Cayrol R, Haqqani AS, Ifergan I, Dodelet-Devillers A, Prat A. Isolation of human brain endothelial cells and characterization of lipid raft-associated proteins by mass spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 686: 275-95. PMID 21082377 DOI: 10.1007/978-1-60761-938-3_13  0.793
2011 Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B. Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathology and Applied Neurobiology. 37: 24-39. PMID 20946472 DOI: 10.1111/J.1365-2990.2010.01140.X  0.469
2011 Alvarez JI, Cayrol R, Prat A. Disruption of central nervous system barriers in multiple sclerosis. Biochimica Et Biophysica Acta. 1812: 252-64. PMID 20619340 DOI: 10.1016/J.Bbadis.2010.06.017  0.758
2010 Laplante P, Sirois I, Raymond MA, Kokta V, Béliveau A, Prat A, Pshezhetsky AV, Hébert MJ. Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis. Cell Death and Differentiation. 17: 291-303. PMID 19730442 DOI: 10.1038/Cdd.2009.124  0.329
2010 Larochelle C, Cayrol R, Kebir H, Ifergan I, Alvarez J, Viel E, Bourbonnière L, Haqqani A, Stanimirovic D, Arbour N, Prat A. MCAM/CD146 Defines and Regulates the Function of a Population of Human Effector Memory Th17 Lymphocytes Subset Involved in Neuroinflammation Clinical Immunology. 135: S122. DOI: 10.1016/J.Clim.2010.03.366  0.777
2010 Alvarez J, Godschalk A, Terouz S, Prat A. Nascent Multiple Sclerosis Lesions are Associated with Early Disturbances in the Blood–brain Barrier Clinical Immunology. 135: S102-S103. DOI: 10.1016/J.Clim.2010.03.308  0.33
2010 Alvarez J, Dodelet-Devillers A, Ifergan I, Kebir H, Sabbagh M, Wosik K, de Vries E, van Horssen J, Fabre P, Charron F, Prat A. The Hedgehog Pathway Sustains Blood–brain Barrier Properties and Promotes CNS Immune Quiescence Clinical Immunology. 135: S68. DOI: 10.1016/J.Clim.2010.03.208  0.653
2010 Ifergan I, Kebir H, Terouz S, Alvarez J, Bourbonnière L, David S, López-Vales R, Birchler T, Prat A. Ninjurin-1 Controls the Recruitment of Antigen-presenting Cells to the CNS and the Development of Neuroinflammation Clinical Immunology. 135: S35-S36. DOI: 10.1016/J.Clim.2010.03.110  0.664
2009 Kebir H, Ifergan I, Alvarez JI, Bernard M, Poirier J, Arbour N, Duquette P, Prat A. Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis. Annals of Neurology. 66: 390-402. PMID 19810097 DOI: 10.1002/Ana.21748  0.7
2009 Schulze-Topphoff U, Prat A, Prozorovski T, Siffrin V, Paterka M, Herz J, Bendix I, Ifergan I, Schadock I, Mori MA, Van Horssen J, Schröter F, Smorodchenko A, Han MH, Bader M, et al. Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system. Nature Medicine. 15: 788-93. PMID 19561616 DOI: 10.1038/Nm.1980  0.72
2009 Dodelet-Devillers A, Cayrol R, van Horssen J, Haqqani AS, de Vries HE, Engelhardt B, Greenwood J, Prat A. Functions of lipid raft membrane microdomains at the blood-brain barrier. Journal of Molecular Medicine (Berlin, Germany). 87: 765-74. PMID 19484210 DOI: 10.1007/S00109-009-0488-6  0.711
2009 Chintawar S, Cayrol R, Antel J, Pandolfo M, Prat A. Blood-brain barrier promotes differentiation of human fetal neural precursor cells. Stem Cells (Dayton, Ohio). 27: 838-46. PMID 19350685 DOI: 10.1002/Stem.25  0.764
2009 Sabbagh M, Ifergan I, Moumdjian R, Nalbantoglu J, Prat A. OR.92. Human Glioblastoma Cancer Stem Cells Promote Intra-tumoral Immune Regulatory Functions Clinical Immunology. 131: S38. DOI: 10.1016/J.Clim.2009.03.107  0.641
2009 Alvarez J, Dodelet-Devillers A, Ifergan I, Bernard M, Van Horssen J, Charron F, Prat A. OR.81. Astrocyte-secreted Sonic Hedgehog Supports CNS Anti-inflammatory Activity and Promotes Optimal Human Blood Brain Barrier Functioning Clinical Immunology. 131: S34. DOI: 10.1016/J.Clim.2009.03.096  0.693
2009 Kebir H, Ifergan I, Alvarez J, Bernard M, Poirier J, Duquette P, Prat A. OR.56. Preferential Recruitment of IL-17 and IFN-γ Co-expressing CD4+T Lymphocytes Into the Central Nervous System Clinical Immunology. 131: S24-S25. DOI: 10.1016/J.Clim.2009.03.068  0.683
2009 Cayrol R, Kebir H, Ifergan I, Dodelet-Devillers A, Terouz S, Haqqani A, Poirier J, Stanimirovic D, Duquette P, Arbour N, Prat A. OR.21. MCAM/CD146 is Expressed by Brain Endothelial Cells and Defines a Unique Effector Memory Lymphocyte Subset Involved in Neuroinflammation Clinical Immunology. 131: S12. DOI: 10.1016/J.Clim.2009.03.028  0.8
2009 Ifergan I, Kebir H, Marceau G, Bernard M, Talbot P, Arbour N, Prat A. OR.18. VLA-4-Dependent Recruitment of Effector Memory CD8+T Lymphocytes into the Central Nervous System Clinical Immunology. 131: S11. DOI: 10.1016/J.Clim.2009.03.025  0.671
2009 Terouz S, Kebir H, Ifergan I, Dodelet-Devillers A, Bernard M, Horssen JV, Stanimirovic D, Prat A. OR.17. Ninjurin-1 is a Novel Adhesion Molecule of the Blood-brain Barrier Involved in the Recruitment of Monocytes to the Central Nervous System Clinical Immunology. 131: S10-S11. DOI: 10.1016/J.Clim.2009.03.024  0.705
2008 Vincent T, Saikali P, Cayrol R, Roth AD, Bar-Or A, Prat A, Antel JP. Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment. Journal of Immunology (Baltimore, Md. : 1950). 181: 5730-7. PMID 18832732 DOI: 10.4049/Jimmunol.181.8.5730  0.776
2008 Niemelä J, Ifergan I, Yegutkin GG, Jalkanen S, Prat A, Airas L. IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier. European Journal of Immunology. 38: 2718-26. PMID 18825744 DOI: 10.1002/Eji.200838437  0.679
2008 Schulze-Topphoff U, Prat A, Bader M, Zipp F, Aktas O. Roles of the kallikrein/kinin system in the adaptive immune system. International Immunopharmacology. 8: 155-160. PMID 18182219 DOI: 10.1016/J.Intimp.2007.08.001  0.396
2008 Cayrol R, Wosik K, Berard JL, Dodelet-Devillers A, Ifergan I, Kebir H, Haqqani AS, Kreymborg K, Krug S, Moumdjian R, Bouthillier A, Becher B, Arbour N, David S, Stanimirovic D, ... Prat A, et al. Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system. Nature Immunology. 9: 137-45. PMID 18157132 DOI: 10.1038/Ni1551  0.826
2008 Ifergan I, Kébir H, Bernard M, Wosik K, Dodelet-Devillers A, Cayrol R, Arbour N, Prat A. The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. Brain : a Journal of Neurology. 131: 785-99. PMID 18156156 DOI: 10.1093/Brain/Awm295  0.816
2008 Ifergan I, Kebir H, Arbour N, Prat A. F.24. Inflamed CNS-Endothelial Barrier Promotes Recruitment of Effector Memory CD8+ T Lymphocytes Clinical Immunology. 127: S50-S51. DOI: 10.1016/J.Clim.2008.03.136  0.675
2008 Ifergan I, Kebir H, Dodelet-Devillers A, Cayrol R, Arbour N, Prat A. OR.99. The Blood-brain Barrier Induces Differentiation of Migrating Monocytes into Th17-polarizing Dendritic Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.106  0.794
2008 Bar-Or A, Touil T, Kebir H, Jalili F, Hilliker K, Theoret G, Bowman M, Prat A, Freedman M, Atkins H. OR.96. The Abrogation of Inflammatory Disease Activity in MS Patients Treated with Immune Ablation and Autologous Haematopoetic Stem-cell Transplantation (AHSCT) is Associated with Significant Decreases in ThIL-17, but not Th1 Responses Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.103  0.375
2007 Kebir H, Kreymborg K, Ifergan I, Dodelet-Devillers A, Cayrol R, Bernard M, Giuliani F, Arbour N, Becher B, Prat A. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nature Medicine. 13: 1173-5. PMID 17828272 DOI: 10.1038/Nm1651  0.815
2007 Jack CS, Arbour N, Blain M, Meier UC, Prat A, Antel JP. Th1 polarization of CD4+ T cells by Toll-like receptor 3-activated human microglia. Journal of Neuropathology and Experimental Neurology. 66: 848-59. PMID 17805015 DOI: 10.1097/Nen.0B013E3181492A7  0.601
2007 Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A. Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9032-42. PMID 17715340 DOI: 10.1523/Jneurosci.2088-07.2007  0.745
2007 Wosik K, Biernacki K, Khouzam MP, Prat A. Death receptor expression and function at the human blood brain barrier. Journal of the Neurological Sciences. 259: 53-60. PMID 17395209 DOI: 10.1016/J.Jns.2006.08.018  0.467
2007 Lee G, Babakhanian K, Ramaswamy M, Prat A, Wosik K, Bendayan R. Expression of the ATP-binding cassette membrane transporter, ABCG2, in human and rodent brain microvessel endothelial and glial cell culture systems. Pharmaceutical Research. 24: 1262-74. PMID 17380269 DOI: 10.1007/S11095-007-9244-1  0.358
2007 Saikali P, Antel JP, Newcombe J, Chen Z, Freedman M, Blain M, Cayrol R, Prat A, Hall JA, Arbour N. NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1220-8. PMID 17267578 DOI: 10.1523/Jneurosci.4402-06.2007  0.785
2007 Kebir H, Ifergan I, Dodelet-Devillers A, Giuliani F, Cayrol R, Arbour N, Prat A. Cytotoxic Human IL-22-expressing Th17 Lymphocytes Promote Immune Cell Migration Into the Central Nervous System Clinical Immunology. 123: S60. DOI: 10.1016/J.Clim.2007.03.351  0.792
2007 Ifergan I, Kebir H, Arbour N, Prat A. Human Blood–brain Barrier-associated DCs Originate from Blood Monocytes and Polarize CD4+ Lymphocytes into Th17 or Th1 Clinical Immunology. 123: S151-S152. DOI: 10.1016/J.Clim.2007.03.071  0.681
2007 Cayrol R, Dodelet-Devillers A, Ifergan I, Haqqani A, Kebir H, Stanimirovic D, Prat A. ALCAM is a Novel Adhesion Molecule of the Inflammed Endothelium Involved in Leukocyte Trafficking to the Central Nervous System Clinical Immunology. 123: S137. DOI: 10.1016/J.Clim.2007.03.028  0.775
2006 Ifergan I, Wosik K, Cayrol R, Kébir H, Auger C, Bernard M, Bouthillier A, Moumdjian R, Duquette P, Prat A. Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis. Annals of Neurology. 60: 45-55. PMID 16729291 DOI: 10.1002/Ana.20875  0.812
2005 Prat A, Antel J. Pathogenesis of multiple sclerosis. Current Opinion in Neurology. 18: 225-30. PMID 15891404 DOI: 10.1097/01.Wco.0000169737.99040.31  0.563
2005 Prat A, Biernacki K, Saroli T, Orav JE, Guttmann CR, Weiner HL, Khoury SJ, Antel JP. Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. Archives of Neurology. 62: 795-800. PMID 15883268 DOI: 10.1001/Archneur.62.5.795  0.56
2005 Prat A, Biernacki K, Antel JP. Th1 and Th2 lymphocyte migration across the human BBB is specifically regulated by interferon beta and copolymer-1. Journal of Autoimmunity. 24: 119-24. PMID 15829404 DOI: 10.1016/J.Jaut.2005.01.004  0.638
2005 Biernacki K, Antel JP, Blain M, Narayanan S, Arnold DL, Prat A. Interferon beta promotes nerve growth factor secretion early in the course of multiple sclerosis. Archives of Neurology. 62: 563-8. PMID 15824253 DOI: 10.1001/Archneur.62.4.563  0.601
2004 Kim HJ, Biernacki K, Prat A, Antel JP, Bar-Or A. Inflammatory potential and migratory capacities across human brain endothelial cells of distinct glatiramer acetate-reactive T cells generated in treated multiple sclerosis patients. Clinical Immunology (Orlando, Fla.). 111: 38-46. PMID 15093550 DOI: 10.1016/J.Clim.2004.01.004  0.611
2004 Biernacki K, Prat A, Blain M, Antel JP. Regulation of cellular and molecular trafficking across human brain endothelial cells by Th1- and Th2-polarized lymphocytes. Journal of Neuropathology and Experimental Neurology. 63: 223-32. PMID 15055446 DOI: 10.1093/Jnen/63.3.223  0.651
2003 Séguin R, Biernacki K, Rotondo RL, Prat A, Antel JP. Regulation and functional effects of monocyte migration across human brain-derived endothelial cells. Journal of Neuropathology and Experimental Neurology. 62: 412-9. PMID 12722833 DOI: 10.1093/Jnen/62.4.412  0.643
2003 Alter A, Duddy M, Hebert S, Biernacki K, Prat A, Antel JP, Yong VW, Nuttall RK, Pennington CJ, Edwards DR, Bar-Or A. Determinants of human B cell migration across brain endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4497-505. PMID 12707326 DOI: 10.4049/Jimmunol.170.9.4497  0.619
2003 Séguin R, Biernacki K, Prat A, Wosik K, Kim HJ, Blain M, McCrea E, Bar-Or A, Antel JP. Differential effects of Th1 and Th2 lymphocyte supernatants on human microglia. Glia. 42: 36-45. PMID 12594735 DOI: 10.1002/Glia.10201  0.625
2003 Séguin R, Moditi Z, Rotondo R, Biernacki K, Wosik K, Prat A, Antel JP. Human brain endothelial cells supply support for monocyte immunoregulatory functions. Journal of Neuroimmunology. 135: 96-106. PMID 12576229 DOI: 10.1016/S0165-5728(02)00431-9  0.632
2002 Prat A, Biernacki K, Lavoie JF, Poirier J, Duquette P, Antel JP. Migration of multiple sclerosis lymphocytes through brain endothelium. Archives of Neurology. 59: 391-7. PMID 11890842 DOI: 10.1001/Archneur.59.3.391  0.642
2001 Biernacki K, Prat A, Blain M, Antel JP. Regulation of Th1 and Th2 lymphocyte migration by human adult brain endothelial cells Journal of Neuropathology and Experimental Neurology. 60: 1127-1136. PMID 11764086 DOI: 10.1093/Jnen/60.12.1127  0.469
2001 Pouly S, Prat A, Blain M, Olivier A, Antel J. NG2 immunoreactivity on human brain endothelial cells Acta Neuropathologica. 102: 313-320. PMID 11603805 DOI: 10.1007/S004010000350  0.408
2001 Prat A, Biernacki K, Wosik K, Antel JP. Glial cell influence on the human blood-brain barrier Glia. 36: 145-155. PMID 11596123 DOI: 10.1002/Glia.1104  0.492
2001 Calabresi PA, Prat A, Biernacki K, Rollins J, Antel JP. T lymphocytes conditioned with Interferon beta induce membrane and soluble VCAM on human brain endothelial cells. Journal of Neuroimmunology. 115: 161-7. PMID 11282166 DOI: 10.1016/S0165-5728(01)00253-3  0.491
2000 Prat A, Biernacki K, Pouly S, Nalbantoglu J, Couture R, Antel JP. Kinin B1 receptor expression and function on human brain endothelial cells Journal of Neuropathology and Experimental Neurology. 59: 896-906. PMID 11079780 DOI: 10.1093/Jnen/59.10.896  0.319
2000 Qin Y, Zhang DQ, Prat A, Pouly S, Antel J. Characterization of T cell lines derived from glatiramer-acetate-treated multiple sclerosis patients Journal of Neuroimmunology. 108: 201-206. PMID 10900354 DOI: 10.1016/S0165-5728(00)00263-0  0.33
2000 Antel J, Prat A. Antigen and superantigen presentation in the human CNS Journal of Neuroimmunology. 107: 118-123. PMID 10854645 DOI: 10.1016/S0165-5728(00)00229-0  0.303
2000 Prat A, Biernacki K, Becher B, Antel JP. B7 expression and antigen presentation by human brain endothelial cells: Requirement for proinflammatory cytokines Journal of Neuropathology and Experimental Neurology. 59: 129-136. PMID 10749102 DOI: 10.1093/Jnen/59.2.129  0.503
2000 Prat A, Pelletier D, Duquette P, Arnold DL, Antel JP. Heterogeneity of T-lymphocyte function in primary progressive multiple sclerosis: Relation to magnetic resonance imaging lesion volume Annals of Neurology. 47: 234-237. PMID 10665495 DOI: 10.1002/1531-8249(200002)47:2<234::Aid-Ana14>3.0.Co;2-S  0.347
2000 Becher B, Prat A, Antel JP. Brain-immune connection: Immuno-regulatory properties of CNS-resident cells Glia. 29: 293-304. PMID 10652440 DOI: 10.1002/(Sici)1098-1136(20000215)29:4<293::Aid-Glia1>3.0.Co;2-A  0.43
1999 Prat A, Weinrib L, Becher B, Poirier J, Duquette P, Couture R, Antel JP. Bradykinin B1 receptor expression and function on T lymphocytes in active multiple sclerosis Neurology. 53: 2087-2092. PMID 10599786 DOI: 10.1212/Wnl.53.9.2087  0.414
1999 Prat A, Al-Asmi A, Duquette P, Antel JP. Lymphocyte migration and multiple sclerosis: Relation with disease course and therapy Annals of Neurology. 46: 253-256. PMID 10443892 DOI: 10.1002/1531-8249(199908)46:2<253::Aid-Ana16>3.0.Co;2-C  0.394
1999 Becher B, Giacomini PS, Pelletier D, McCrea E, Prat A, Antel JP. Interferon-? secretion by peripheral blood T-cell subsets in multiple sclerosis: Correlation with disease phase and interferon-? therapy Annals of Neurology. 45: 247-250. DOI: 10.1002/1531-8249(199902)45:2<247::Aid-Ana16>3.0.Co;2-U  0.445
1998 Prat A, Becher B, Blain M, Antel J. Induction of B7.1 and B7.2 co-stimulatory molecule on the surface of human brain endothelial cells Journal of Neuroimmunology. 90: 24. DOI: 10.1016/S0165-5728(98)91325-X  0.354
1998 Prat A, Weinrib L, Becher B, Duquette P, Couture R, Antel J. Bradykinin B1 receptor regulates the migration of lymphocytes in multiple sclerosis Journal of Neuroimmunology. 90: 24. DOI: 10.1016/S0165-5728(98)91324-8  0.344
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