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Norbert F. Voelkel - Publications

Affiliations: 
Biochemistry Virginia Commonwealth University, Richmond, VA, United States 
Area:
Genetics, Cell Biology
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354 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fließer E, Jandl K, Lins T, Birnhuber A, Valzano F, Kolb D, Foris V, Heinemann A, Olschewski H, Evermann M, Hoetzenecker K, Kreuter M, Voelkel NF, Marsh LM, Wygrecka M, et al. Lung Fibrosis Is Linked to Increased Endothelial Cell Activation and Dysfunctional Vascular Barrier Integrity. American Journal of Respiratory Cell and Molecular Biology. PMID 38843440 DOI: 10.1165/rcmb.2024-0046OC  0.386
2023 Borek I, Birnhuber A, Voelkel NF, Marsh LM, Kwapiszewska G. The vascular perspective on acute and chronic lung disease. The Journal of Clinical Investigation. 133. PMID 37581311 DOI: 10.1172/JCI170502  0.445
2021 Voelkel NF, Bogaard HJ. Sugen, hypoxia and the lung circulation. Pulmonary Circulation. 11: 20458940211051188. PMID 34631012 DOI: 10.1177/20458940211051188  0.302
2021 Tian W, Jiang SY, Jiang X, Tamosiuniene R, Kim D, Guan T, Arsalane S, Pasupneti S, Voelkel NF, Tang Q, Nicolls MR. The Role of Regulatory T Cells in Pulmonary Arterial Hypertension. Frontiers in Immunology. 12: 684657. PMID 34489935 DOI: 10.3389/fimmu.2021.684657  0.446
2021 Miwa H, Sakao S, Sanada TJ, Suzuki H, Hata A, Shiina Y, Kobayashi T, Kato F, Nishimura R, Tanabe N, Voelkel N, Yoshino I, Tatsumi K. Cell tracking suggests pathophysiological and therapeutic role of bone marrow cells in Sugen5416/hypoxia rat model of pulmonary arterial hypertension. The Canadian Journal of Cardiology. PMID 33609715 DOI: 10.1016/j.cjca.2021.02.006  0.406
2020 Gomez-Arroyo J, Voelkel NF, Abbate A. SCUBE Diving: Biomarker Discovery for Pulmonary Hypertension From Bench to Bedside. Jacc. Basic to Translational Science. 5: 1093-1094. PMID 33296445 DOI: 10.1016/j.jacbts.2020.09.009  0.743
2020 Voelkel NF, Peters-Golden M. A new treatment for severe pulmonary arterial hypertension based on an old idea: inhibition of 5-lipoxygenase. Pulmonary Circulation. 10: 2045894019882635. PMID 32257113 DOI: 10.1177/2045894019882635  0.461
2020 Sandoval J, Del Valle-Mondragón L, Masso F, Zayas N, Pulido T, Teijeiro R, Gonzalez-Pacheco H, Olmedo-Ocampo R, Sisniega C, Paez-Arenas A, Pastelin-Hernandez G, Gomez-Arroyo J, Voelkel NF. Angiotensin Converting Enzyme 2 and Angiotensin (1-7) axis in Pulmonary Arterial Hypertension. The European Respiratory Journal. PMID 32241831 DOI: 10.1183/13993003.02416-2019  0.718
2020 Agarwal S, Harter ZJ, Krishnamachary B, Chen L, Nguyen T, Voelkel NF, Dhillon NK. Sugen-morphine model of pulmonary arterial hypertension. Pulmonary Circulation. 10: 2045894019898376. PMID 32110385 DOI: 10.1177/2045894019898376  0.481
2020 Cool CD, Kuebler WM, Bogaard HJ, Spiekerkoetter E, Nicolls MR, Voelkel NF. The Hallmarks of Severe Pulmonary Arterial Hypertension: The Cancer Hypothesis - Ten years later. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32023082 DOI: 10.1152/ajplung.00476.2019  0.431
2019 Spiekerkoetter E, Goncharova EA, Guignabert C, Stenmark K, Kwapiszewska G, Rabinovitch M, Voelkel N, Bogaard HJ, Graham B, Pullamsetti SS, Kuebler WM. Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure. Pulmonary Circulation. 9: 2045894019889775. PMID 31798835 DOI: 10.1177/2045894019889775  0.468
2019 Tian W, Jiang X, Sung YK, Shuffle E, Wu TH, Kao PN, Tu AB, Dorfmüller P, Cao A, Wang L, Peng G, Kim Y, Zhang P, Chappell J, Pasupneti S, ... ... Voelkel NF, et al. Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation. Circulation. PMID 31462075 DOI: 10.1161/Circulationaha.119.040629  0.525
2019 Kwapiszewska G, Johansen AKZ, Gomez-Arroyo J, Voelkel NF. The Role of the Aryl Hydrocarbon Receptor/ARNT/Cytochrome P450 System in Pulmonary Vascular Diseases- A Hypothesis. Circulation Research. PMID 31242807 DOI: 10.1161/CIRCRESAHA.119.315054  0.734
2019 Bogaard HJ, Voelkel NF. Is Myocardial Fibrosis Impairing Right Heart Function? American Journal of Respiratory and Critical Care Medicine. PMID 30608865 DOI: 10.1164/Rccm.201812-2307Ed  0.302
2018 Naito A, Sakao S, Lang IM, Voelkel NF, Jujo T, Ishida K, Sugiura T, Matsumiya G, Yoshino I, Tanabe N, Tatsumi K. Endothelial cells from pulmonary endarterectomy specimens possess a high angiogenic potential and express high levels of hepatocyte growth factor. Bmc Pulmonary Medicine. 18: 197. PMID 30594174 DOI: 10.1186/S12890-018-0769-3  0.529
2018 Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, ... ... Voelkel NF, et al. Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement. American Journal of Respiratory and Critical Care Medicine. 198: e15-e43. PMID 30109950 DOI: 10.1164/Rccm.201806-1160St  0.393
2018 Voelkel NF, Newman JH. The Light at the End of the Long Pulmonary Hypertension Tunnel Brightens. American Journal of Respiratory and Critical Care Medicine. PMID 29944843 DOI: 10.1164/Rccm.201802-0325Le  0.459
2018 Kovacs G, Agusti A, Barberà JA, Celli B, Criner G, Humbert M, Sin DD, Voelkel N, Olschewski H. Pulmonary Vascular Involvement in COPD - Is There a Pulmonary Vascular Phenotype? American Journal of Respiratory and Critical Care Medicine. PMID 29746142 DOI: 10.1164/Rccm.201801-0095Pp  0.551
2018 Bauer A, Khalil M, Schmidt D, Bauer J, Esmaeili A, Apitz C, Voelkel N, Schranz D. EXPRESS: Creation of a restrictive atrial communication in Pulmonary Arterial Hypertension (PAH): effective palliation of syncope and end-stage heart failure. Pulmonary Circulation. 2045894018776518. PMID 29693479 DOI: 10.1177/2045894018776518  0.355
2018 Tamosiuniene R, Manouvakhova O, Mesange P, Saito T, Qian J, Sanyal M, Lin YC, Nguyen LP, Luria A, Tu AB, Sante JM, Rabinovitch M, Fitzgerald DJ, Graham BB, Habtezion A, ... Voelkel NF, et al. A Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension. Circulation Research. PMID 29545367 DOI: 10.1161/Circresaha.117.312058  0.428
2018 Orcholski ME, Yuan K, Rajasingh C, Tsai H, Shamskhou EA, Dhillon NK, Voelkel NF, Zamanian RT, de Jesus Perez VA. DRUG INDUCED PULMONARY ARTERIAL HYPERTENSION: A PRIMER FOR CLINICIANS AND SCIENTISTS. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29417823 DOI: 10.1152/Ajplung.00553.2017  0.438
2017 Gomez-Arroyo J, Voelkel NF, Huizar JF, Abbate A. Targeting Neurohormonal Activation in Pulmonary Arterial Hypertension: Putting the Puzzle Together. Jacc. Basic to Translational Science. 2: 36-38. PMID 30167553 DOI: 10.1016/J.Jacbts.2016.11.003  0.746
2017 Almodovar S, Swanson J, Giavedoni LD, Kanthaswamy S, Long CS, Voelkel NF, Edwards MG, Folkvord JM, Connick E, Westmoreland SV, Luciw PA, Flores SC. Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques. Viral Immunology. PMID 29256819 DOI: 10.1089/Vim.2017.0051  0.432
2017 Tian W, Rockson SG, Jiang X, Kim J, Begaye A, Shuffle EM, Tu AB, Cribb M, Nepiyushchikh Z, Feroze AH, Zamanian RT, Dhillon GS, Voelkel NF, Peters-Golden M, Kitajewski J, et al. Leukotriene B4 antagonism ameliorates experimental lymphedema. Science Translational Medicine. 9. PMID 28490670 DOI: 10.1126/Scitranslmed.Aal3920  0.316
2017 Mizuno S, Ishizaki T, Kadowaki M, Akai M, Shiozaki K, Iguchi M, Oikawa T, Nakagawa K, Osanai K, Toga H, Gomez-Arroyo J, Kraskauskas D, Cool CD, Bogaard HJ, Voelkel NF. p53 signaling pathway polymorphisms associated with emphysematous changes in COPD patients. Chest. PMID 28315337 DOI: 10.1016/J.Chest.2017.03.012  0.673
2016 Schranz D, Akintuerk H, Voelkel NF. 'End-stage' heart failure therapy: potential lessons from congenital heart disease: from pulmonary artery banding and interatrial communication to parallel circulation. Heart (British Cardiac Society). PMID 28011759 DOI: 10.1136/heartjnl-2015-309110  0.38
2016 Voelkel NF, Bogaard HJ. Adding complexity to plexogenic arteriopathy. The European Respiratory Journal. 48: 1553-1555. PMID 27903686 DOI: 10.1183/13993003.01867-2016  0.447
2016 Nicolls MR, Voelkel NF. The Roles of Immunity in the Prevention and Evolution of Pulmonary Arterial Hypertension. A Perspective. American Journal of Respiratory and Critical Care Medicine. PMID 27786553 DOI: 10.1164/Rccm.201608-1630Pp  0.534
2016 Kato R, Mizuno S, Kadowaki M, Shiozaki K, Akai M, Nakagawa K, Oikawa T, Iguchi M, Osanai K, Ishizaki T, Voelkel NF, Toga H. Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease. Respiratory Research. 17: 139. PMID 27784320 DOI: 10.1186/S12931-016-0452-2  0.455
2016 Gomez-Arroyo J, Abbate A, Voelkel NF. Pulmonary arterial hypertension and the Enigma code of smouldering inflammation. The European Respiratory Journal. 48: 305-7. PMID 27478186 DOI: 10.1183/13993003.00996-2016  0.723
2016 Zhou C, Townsley MI, Alexeyev M, Voelkel NF, Stevens T. Endothelial hyperpermeability in severe pulmonary arterial hypertension: Role of store operated calcium entry. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00057.2016. PMID 27422996 DOI: 10.1152/Ajplung.00057.2016  0.539
2016 Sakao S, Daimon M, Voelkel NF, Miyauchi H, Jujo T, Sugiura T, Ishida K, Tanabe N, Kobayashi Y, Tatsumi K. Right ventricular sugars and fats in chronic thromboembolic pulmonary hypertension. International Journal of Cardiology. 219: 143-149. PMID 27323340 DOI: 10.1016/J.Ijcard.2016.06.010  0.455
2016 Voelkel NF, Tamosiuniene R, Nicolls MR. Challenges and opportunities in treating inflammation associated with pulmonary hypertension. Expert Review of Cardiovascular Therapy. PMID 27096622 DOI: 10.1080/14779072.2016.1180976  0.525
2016 Happé CM, De Raaf MA, Rol N, Schalij I, Vonk-Noordegraaf A, Westerhof N, Voelkel NF, de Man FS, Bogaard HJ. Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00023.2016. PMID 27036867 DOI: 10.1152/Ajplung.00023.2016  0.543
2016 Schranz D, Voelkel NF. "Nihilism" of chronic heart failure therapy in children and why effective therapy is withheld. European Journal of Pediatrics. 175: 445-55. PMID 26895877 DOI: 10.1007/S00431-016-2700-3  0.301
2016 van de Veerdonk MC, Bogaard HJ, Voelkel NF. The right ventricle and pulmonary hypertension. Heart Failure Reviews. PMID 26833318 DOI: 10.1007/S10741-016-9526-Y  0.462
2016 Happé CM, Szulcek R, Voelkel NF, Bogaard HJ. Reconciling paradigms of abnormal pulmonary blood flow and quasi-malignant cellular alterations in pulmonary arterial hypertension. Vascular Pharmacology. 83: 17-25. PMID 26804008 DOI: 10.1016/J.Vph.2016.01.004  0.576
2015 Qian J, Tian W, Jiang X, Tamosiuniene R, Sung YK, Shuffle EM, Tu AB, Valenzuela A, Jiang S, Zamanian RT, Fiorentino DF, Voelkel NF, Peters-Golden M, Stenmark KR, Chung L, et al. Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension. Hypertension. 66: 1227-39. PMID 26558820 DOI: 10.1161/Hypertensionaha.115.06370  0.563
2015 De Raaf MA, Kroeze Y, Middelman A, de Man FS, de Jong H, Vonk Noordegraaf A, de Korte C, Voelkel NF, Homberg J, Bogaard HJ. Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00127.2015. PMID 26386116 DOI: 10.1152/Ajplung.00127.2015  0.534
2015 Sakao S, Miyauchi H, Voelkel NF, Sugiura T, Tanabe N, Kobayashi Y, Tatsumi K. Increased Right Ventricular Fatty Acid Accumulation in Chronic Thromboembolic Pulmonary Hypertension. Annals of the American Thoracic Society. 12: 1465-72. PMID 26356218 DOI: 10.1513/Annalsats.201504-236Le  0.443
2015 Sakao S, Voelkel NF, Tanabe N, Tatsumi K. Determinants of an elevated pulmonary arterial pressure in patients with pulmonary arterial hypertension. Respiratory Research. 16: 84. PMID 26150101 DOI: 10.1186/S12931-015-0246-Y  0.557
2015 Al-Husseini A, Kraskauskas D, Mezzaroma E, Nordio A, Farkas D, Drake JI, Abbate A, Felty Q, Voelkel NF. Vascular endothelial growth factor receptor 3 signaling contributes to angioobliterative pulmonary hypertension. Pulmonary Circulation. 5: 101-16. PMID 25992275 DOI: 10.1086/679704  0.485
2015 Voelkel NF, Bogaard HJ, Gomez-Arroyo J. The need to recognize the pulmonary circulation and the right ventricle as an integrated functional unit: facts and hypotheses (2013 Grover Conference series). Pulmonary Circulation. 5: 81-9. PMID 25992273 DOI: 10.1086/679702  0.726
2015 Al-Husseini A, Wijesinghe DS, Farkas L, Kraskauskas D, Drake JI, Van Tassel B, Abbate A, Chalfant CE, Voelkel NF. Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. Plos One. 10: e0120157. PMID 25785937 DOI: 10.1371/Journal.Pone.0120157  0.59
2015 Abbate A, Arena R, Abouzaki N, Van Tassell BW, Canada J, Shah K, Biondi-Zoccai G, Voelkel NF. Heart failure with preserved ejection fraction: refocusing on diastole. International Journal of Cardiology. 179: 430-40. PMID 25465302 DOI: 10.1016/J.Ijcard.2014.11.106  0.31
2015 Gomez-Arroyo J, Sakagami M, Syed AA, Farkas L, Van Tassell B, Kraskauskas D, Mizuno S, Abbate A, Bogaard HJ, Byron PR, Voelkel NF. Iloprost reverses established fibrosis in experimental right ventricular failure. The European Respiratory Journal. 45: 449-62. PMID 25261325 DOI: 10.1183/09031936.00188013  0.756
2015 Qian J, Tian W, Jiang X, Tamosiuniene R, Sung YK, Shuffle EM, Tu AB, Valenzuela A, Jiang S, Zamanian RT, Fiorentino DF, Voelkel NF, Peters-Golden M, Stenmark KR, Chung L, et al. Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension Hypertension. DOI: 10.1161/HYPERTENSIONAHA.115.06370  0.435
2014 Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, Naeije R, Newman J, Oudiz RJ, Provencher S, Torbicki A, Voelkel NF, Hassoun PM. [Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology]. TüRk Kardiyoloji DerneğI ArşIvi : TüRk Kardiyoloji DerneğInin YayıN OrganıDıR. 42: 29-44. PMID 25697032  0.402
2014 Sakao S, Voelkel NF, Tatsumi K. The vascular bed in COPD: pulmonary hypertension and pulmonary vascular alterations. European Respiratory Review : An Official Journal of the European Respiratory Society. 23: 350-5. PMID 25176971 DOI: 10.1183/09059180.00007913  0.586
2014 Gomez-Arroyo J, Sandoval J, Simon MA, Dominguez-Cano E, Voelkel NF, Bogaard HJ. Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction. Annals of the American Thoracic Society. 11: 1101-15. PMID 25079379 DOI: 10.1513/Annalsats.201312-425Fr  0.773
2014 De Raaf MA, Hussaini AA, Gomez-Arroyo J, Kraskaukas D, Farkas D, Happé C, Voelkel NF, Bogaard HJ. Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series). Pulmonary Circulation. 4: 237-43. PMID 25006442 DOI: 10.1086/675986  0.779
2014 Voelkel NF, Gomez-Arroyo J. The role of vascular endothelial growth factor in pulmonary arterial hypertension. The angiogenesis paradox. American Journal of Respiratory Cell and Molecular Biology. 51: 474-84. PMID 24932885 DOI: 10.1165/Rcmb.2014-0045Tr  0.754
2014 Grinnan D, Bogaard HJ, Grizzard J, Van Tassell B, Abbate A, DeWilde C, Priday A, Voelkel NF. Treatment of group I pulmonary arterial hypertension with carvedilol is safe. American Journal of Respiratory and Critical Care Medicine. 189: 1562-4. PMID 24930531 DOI: 10.1164/Rccm.201311-2025Le  0.486
2014 Saluja B, Li H, Desai UR, Voelkel NF, Sakagami M. Sulfated caffeic acid dehydropolymer attenuates elastase and cigarette smoke extract-induced emphysema in rats: sustained activity and a need of pulmonary delivery. Lung. 192: 481-92. PMID 24831783 DOI: 10.1007/S00408-014-9597-2  0.338
2014 de Raaf MA, Schalij I, Gomez-Arroyo J, Rol N, Happé C, de Man FS, Vonk-Noordegraaf A, Westerhof N, Voelkel NF, Bogaard HJ. SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction. The European Respiratory Journal. 44: 160-8. PMID 24791833 DOI: 10.1183/09031936.00204813  0.765
2014 Farkas D, Kraskauskas D, Drake JI, Alhussaini AA, Kraskauskiene V, Bogaard HJ, Cool CD, Voelkel NF, Farkas L. CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit⁺ cells in rats. Plos One. 9: e89810. PMID 24587052 DOI: 10.1371/Journal.Pone.0089810  0.539
2014 Gomez-Arroyo J, Santos-Martinez LE, Aranda A, Pulido T, Beltran M, Muñoz-Castellanos L, Dominguez-Cano E, Sonnino C, Voelkel NF, Sandoval J. Differences in right ventricular remodeling secondary to pressure overload in patients with pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 189: 603-6. PMID 24579837 DOI: 10.1164/Rccm.201309-1711Le  0.743
2014 Voelkel NF, Humbert M. Translational research in pulmonary hypertension: challenge and opportunity. The European Respiratory Journal. 43: 325-8. PMID 24488987 DOI: 10.1183/09031936.00125313  0.523
2013 Voelkel NF. Pulmonary vascular diseases: in search of a hub among the spokes-an exercise in hypothesis generation. Pulmonary Circulation. 3: 723-7. PMID 25006390 DOI: 10.1086/674771  0.43
2013 Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, Naeije R, Newman J, Oudiz RJ, Provencher S, Torbicki A, Voelkel NF, Hassoun PM. Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. Journal of the American College of Cardiology. 62: D22-33. PMID 24355638 DOI: 10.1016/j.jacc.2013.10.027  0.404
2013 Voelkel NF, Mizuno S, Yasuo M. Does drug-induced emphysema exist? The European Respiratory Journal. 42: 1464-8. PMID 24293420 DOI: 10.1183/09031936.00110513  0.446
2013 Tian W, Jiang X, Tamosiuniene R, Sung YK, Qian J, Dhillon G, Gera L, Farkas L, Rabinovitch M, Zamanian RT, Inayathullah M, Fridlib M, Rajadas J, Peters-Golden M, Voelkel NF, et al. Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension. Science Translational Medicine. 5: 200ra117. PMID 23986401 DOI: 10.1126/Scitranslmed.3006674  0.489
2013 Voelkel NF, Gomez-Arroyo J, Abbate A, Bogaard HJ. Mechanisms of right heart failure-A work in progress and a plea for failure prevention. Pulmonary Circulation. 3: 137-43. PMID 23662190 DOI: 10.4103/2045-8932.109957  0.643
2013 Drake JI, Gomez-Arroyo J, Dumur CI, Kraskauskas D, Natarajan R, Bogaard HJ, Fawcett P, Voelkel NF. Chronic carvedilol treatment partially reverses the right ventricular failure transcriptional profile in experimental pulmonary hypertension. Physiological Genomics. 45: 449-61. PMID 23632417 DOI: 10.1152/Physiolgenomics.00166.2012  0.715
2013 Bogaard HJ, Mizuno S, Voelkel NF. Letter by Bogaard et al regarding article, "histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid". Circulation. 127: e539. PMID 23569123 DOI: 10.1161/Circulationaha.112.127092  0.528
2013 Voelkel NF, Mizuno S, Bogaard HJ. The role of hypoxia in pulmonary vascular diseases: a perspective. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L457-65. PMID 23377344 DOI: 10.1152/Ajplung.00335.2012  0.537
2013 Yasuo M, Mizuno S, Allegood J, Kraskauskas D, Bogaard HJ, Spiegel S, Voelkel NF. Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate. Plos One. 8: e53927. PMID 23326540 DOI: 10.1371/Journal.Pone.0053927  0.432
2013 Gomez-Arroyo J, Mizuno S, Szczepanek K, Van Tassell B, Natarajan R, dos Remedios CG, Drake JI, Farkas L, Kraskauskas D, Wijesinghe DS, Chalfant CE, Bigbee J, Abbate A, Lesnefsky EJ, Bogaard HJ, ... Voelkel NF, et al. Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension. Circulation. Heart Failure. 6: 136-44. PMID 23152488 DOI: 10.1161/Circheartfailure.111.966127  0.737
2013 Voelkel NF, Bogaard HJ, Al Husseini A, Farkas L, Gomez-Arroyo J, Natarajan R. Antioxidants for the treatment of patients with severe angioproliferative pulmonary hypertension? Antioxidants & Redox Signaling. 18: 1810-7. PMID 22870869 DOI: 10.1089/Ars.2012.4828  0.785
2013 Al Husseini A, Bagnato G, Farkas L, Gomez-Arroyo J, Farkas D, Mizuno S, Kraskauskas D, Abbate A, Van Tassel B, Voelkel NF, Bogaard HJ. Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats. The European Respiratory Journal. 41: 104-14. PMID 22835607 DOI: 10.1183/09031936.00196511  0.755
2012 Nicolls MR, Mizuno S, Taraseviciene-Stewart L, Farkas L, Drake JI, Al Husseini A, Gomez-Arroyo JG, Voelkel NF, Bogaard HJ. New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary Circulation. 2: 434-42. PMID 23372927 DOI: 10.4103/2045-8932.105031  0.795
2012 Mizuno S, Farkas L, Al Husseini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF. Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. American Journal of Respiratory Cell and Molecular Biology. 47: 679-87. PMID 22842496 DOI: 10.1165/Rcmb.2012-0077Oc  0.773
2012 Morjaria S, Grinnan D, Voelkel N. Massive dilatation of the pulmonary artery in association with pulmonic stenosis and pulmonary hypertension. Pulmonary Circulation. 2: 256-7. PMID 22837867 DOI: 10.4103/2045-8932.97640  0.533
2012 Bogaard HJ, Al Husseini A, Farkas L, Farkas D, Gomez-Arroyo J, Abbate A, Voelkel NF. Severe pulmonary hypertension: The role of metabolic and endocrine disorders. Pulmonary Circulation. 2: 148-54. PMID 22837855 DOI: 10.4103/2045-8932.97592  0.772
2012 Voelkel NF, Gomez-Arroyo J, Abbate A, Bogaard HJ, Nicolls MR. Pathobiology of pulmonary arterial hypertension and right ventricular failure. The European Respiratory Journal. 40: 1555-65. PMID 22743666 DOI: 10.1183/09031936.00046612  0.747
2012 Gomez-Arroyo J, Voelkel NF, Bogaard HJ, Taraseviciene-Stewart L. Usefulness of a mouse model of reversible pulmonary arterial hypertension: be cautious, choose carefully. American Journal of Respiratory and Critical Care Medicine. 185: 1326; author reply 1. PMID 22707737 DOI: 10.1164/Ajrccm.185.12.1326  0.751
2012 Fisher BJ, Kraskauskas D, Martin EJ, Farkas D, Wegelin JA, Brophy D, Ward KR, Voelkel NF, Fowler AA, Natarajan R. Mechanisms of attenuation of abdominal sepsis induced acute lung injury by ascorbic acid. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L20-32. PMID 22523283 DOI: 10.1152/Ajplung.00300.2011  0.384
2012 Spikes L, Dalvi P, Tawfik O, Gu H, Voelkel NF, Cheney P, O'Brien-Ladner A, Dhillon NK. Enhanced pulmonary arteriopathy in simian immunodeficiency virus-infected macaques exposed to morphine American Journal of Respiratory and Critical Care Medicine. 185: 1235-1243. PMID 22447963 DOI: 10.1164/Rccm.201110-1909Oc  0.336
2012 Mizuno S, Bogaard HJ, Gomez-Arroyo J, Alhussaini A, Kraskauskas D, Cool CD, Voelkel NF. MicroRNA-199a-5p is associated with hypoxia-inducible factor-1α expression in lungs from patients with COPD. Chest. 142: 663-72. PMID 22383663 DOI: 10.1378/Chest.11-2746  0.691
2012 Mezzaroma E, Di X, Graves P, Toldo S, Van Tassell BW, Kannan H, Baumgarten C, Voelkel N, Gewirtz DA, Abbate A. A mouse model of radiation-induced cardiomyopathy. International Journal of Cardiology. 156: 231-3. PMID 22340985 DOI: 10.1016/J.Ijcard.2012.01.038  0.319
2012 Kearns MT, Dalal S, Horstmann SA, Richens TR, Tanaka T, Doe JM, Boe DM, Voelkel NF, Taraseviciene-Stewart L, Janssen WJ, Lee CG, Elias JA, Bratton D, Tuder RM, Henson PM, et al. Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L711-8. PMID 22307908 DOI: 10.1152/Ajplung.00116.2011  0.368
2012 Gomez-Arroyo J, Saleem SJ, Mizuno S, Syed AA, Bogaard HJ, Abbate A, Taraseviciene-Stewart L, Sung Y, Kraskauskas D, Farkas D, Conrad DH, Nicolls MR, Voelkel NF. A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L977-91. PMID 22307907 DOI: 10.1152/Ajplung.00362.2011  0.755
2012 Mizuno S, Yasuo M, Bogaard HJ, Kraskauskas D, Alhussaini A, Gomez-Arroyo J, Farkas D, Farkas L, Voelkel NF. Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation. Plos One. 7: e30678. PMID 22276220 DOI: 10.1371/Journal.Pone.0030678  0.632
2012 Van Tassell BW, Bhardwaj HL, Grizzard JD, Kontos MC, Bogaard H, Gomez-Arroyo J, Toldo S, Mezzaroma E, Voelkel NF, Abbate A. Right ventricular systolic dysfunction in patients with reperfused ST-segment elevation acute myocardial infarction. International Journal of Cardiology. 155: 314-6. PMID 22197216 DOI: 10.1016/J.Ijcard.2011.12.004  0.627
2012 Bogaard HJ, Mizuno S, Guignabert C, Al Hussaini AA, Farkas D, Ruiter G, Kraskauskas D, Fadel E, Allegood JC, Humbert M, Vonk Noordegraaf A, Spiegel S, Farkas L, Voelkel NF. Copper dependence of angioproliferation in pulmonary arterial hypertension in rats and humans. American Journal of Respiratory Cell and Molecular Biology. 46: 582-91. PMID 22162909 DOI: 10.1165/Rcmb.2011-0296Oc  0.559
2012 Almodovar S, Knight R, Allshouse AA, Roemer S, Lozupone C, McDonald D, Widmann J, Voelkel NF, Shelton RJ, Suarez EB, Hammer KW, Goujard C, Petrosillo N, Simonneau G, Hsue PY, et al. Human Immunodeficiency Virus nef signature sequences are associated with pulmonary hypertension. Aids Research and Human Retroviruses. 28: 607-18. PMID 22066947 DOI: 10.1089/Aid.2011.0021  0.313
2012 Lee JH, Hanaoka M, Kitaguchi Y, Kraskauskas D, Shapiro L, Voelkel NF, Taraseviciene-Stewart L. Imbalance of apoptosis and cell proliferation contributes to the development and persistence of emphysema. Lung. 190: 69-82. PMID 22015802 DOI: 10.1007/S00408-011-9326-Z  0.366
2012 Gomez-Arroyo JG, Farkas L, Alhussaini AA, Farkas D, Kraskauskas D, Voelkel NF, Bogaard HJ. The monocrotaline model of pulmonary hypertension in perspective. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L363-9. PMID 21964406 DOI: 10.1152/Ajplung.00212.2011  0.776
2012 Maruoka M, Sakao S, Kantake M, Tanabe N, Kasahara Y, Kurosu K, Takiguchi Y, Masuda M, Yoshino I, Voelkel NF, Tatsumi K. Characterization of myofibroblasts in chronic thromboembolic pulmonary hypertension. International Journal of Cardiology. 159: 119-27. PMID 21406312 DOI: 10.1016/J.Ijcard.2011.02.037  0.512
2012 Gomez-Arroyo J, Bogaard HJ, Farkas L, Abbate A, Voelkel NF. Pulmonary hypertension and right ventricular dysfunction in chronic lung diseases: New pathobiologic concepts Current Respiratory Medicine Reviews. 8: 116-122. DOI: 10.2174/157339812799859798  0.77
2011 Voelkel NF, Natarajan R, Drake JI, Bogaard HJ. Right ventricle in pulmonary hypertension. Comprehensive Physiology. 1: 525-40. PMID 23737184 DOI: 10.1002/Cphy.C090008  0.413
2011 Voelkel NF, Gomez-Arroyo J, Mizuno S. COPD/emphysema: The vascular story. Pulmonary Circulation. 1: 320-6. PMID 22140621 DOI: 10.4103/2045-8932.87295  0.781
2011 Tamosiuniene R, Tian W, Dhillon G, Wang L, Sung YK, Gera L, Patterson AJ, Agrawal R, Rabinovitch M, Ambler K, Long CS, Voelkel NF, Nicolls MR. Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension. Circulation Research. 109: 867-79. PMID 21868697 DOI: 10.1161/Circresaha.110.236927  0.502
2011 Farkas L, Farkas D, Warburton D, Gauldie J, Shi W, Stampfli MR, Voelkel NF, Kolb M. Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L391-401. PMID 21743024 DOI: 10.1152/Ajplung.00369.2010  0.303
2011 Voelkel NF, Gomez-Arroyo J. The harmonics of rodent pulmonary hypertension models. International Journal of Clinical Practice. Supplement. 1-2. PMID 21736674 DOI: 10.1111/J.1742-1241.2011.02712.X  0.757
2011 Drake JI, Bogaard HJ, Mizuno S, Clifton B, Xie B, Gao Y, Dumur CI, Fawcett P, Voelkel NF, Natarajan R. Molecular signature of a right heart failure program in chronic severe pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 45: 1239-47. PMID 21719795 DOI: 10.1165/Rcmb.2010-0412Oc  0.423
2011 Cool CD, Voelkel NF, Bull T. Viral infection and pulmonary hypertension: is there an association? Expert Review of Respiratory Medicine. 5: 207-16. PMID 21510731 DOI: 10.1586/Ers.11.17  0.384
2011 Toldo S, Bogaard HJ, Van Tassell BW, Mezzaroma E, Seropian IM, Robati R, Salloum FN, Voelkel NF, Abbate A. Right ventricular dysfunction following acute myocardial infarction in the absence of pulmonary hypertension in the mouse. Plos One. 6: e18102. PMID 21455304 DOI: 10.1371/Journal.Pone.0018102  0.412
2011 Fisher BJ, Seropian IM, Kraskauskas D, Thakkar JN, Voelkel NF, Fowler AA, Natarajan R. Ascorbic acid attenuates lipopolysaccharide-induced acute lung injury. Critical Care Medicine. 39: 1454-60. PMID 21358394 DOI: 10.1097/Ccm.0B013E3182120Cb8  0.346
2011 Mizuno S, Bogaard HJ, Kraskauskas D, Alhussaini A, Gomez-Arroyo J, Voelkel NF, Ishizaki T. p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L753-61. PMID 21335523 DOI: 10.1152/Ajplung.00286.2010  0.749
2011 Bogaard HJ, Mizuno S, Hussaini AA, Toldo S, Abbate A, Kraskauskas D, Kasper M, Natarajan R, Voelkel NF. Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats. American Journal of Respiratory and Critical Care Medicine. 183: 1402-10. PMID 21297075 DOI: 10.1164/Rccm.201007-1106Oc  0.414
2011 Mizuno S, Yasuo M, Bogaard HJ, Kraskauskas D, Natarajan R, Voelkel NF. Inhibition of histone deacetylase causes emphysema. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L402-13. PMID 21224215 DOI: 10.1152/Ajplung.00207.2010  0.462
2011 Farkas L, Gauldie J, Voelkel NF, Kolb M. Pulmonary hypertension and idiopathic pulmonary fibrosis: a tale of angiogenesis, apoptosis, and growth factors. American Journal of Respiratory Cell and Molecular Biology. 45: 1-15. PMID 21057104 DOI: 10.1165/Rcmb.2010-0365Tr  0.518
2011 Hanaoka M, Droma Y, Chen Y, Agatsuma T, Kitaguchi Y, Voelkel NF, Kubo K. Carbocisteine protects against emphysema induced by cigarette smoke extract in rats. Chest. 139: 1101-8. PMID 20847042 DOI: 10.1378/Chest.10-0920  0.324
2011 Wick MJ, Buesing EJ, Wehling CA, Loomis ZL, Cool CD, Zamora MR, Miller YE, Colgan SP, Hersh LB, Voelkel NF, Dempsey EC. Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 183: 330-40. PMID 20813891 DOI: 10.1164/rccm.201002-0154OC  0.467
2011 Yasuo M, Mizuno S, Kraskauskas D, Bogaard HJ, Natarajan R, Cool CD, Zamora M, Voelkel NF. Hypoxia inducible factor-1α in human emphysema lung tissue. The European Respiratory Journal. 37: 775-83. PMID 20562128 DOI: 10.1183/09031936.00022910  0.451
2010 Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, ... ... Voelkel N, et al. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. American Journal of Respiratory and Critical Care Medicine. 182: 1554-62. PMID 20833821 DOI: 10.1164/Rccm.201006-0869Ws  0.457
2010 Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, Voelkel NF, McMurtry IF, Oka M. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation. 121: 2747-54. PMID 20547927 DOI: 10.1161/CIRCULATIONAHA.109.927681  0.445
2010 Bogaard HJ, Natarajan R, Mizuno S, Abbate A, Chang PJ, Chau VQ, Hoke NN, Kraskauskas D, Kasper M, Salloum FN, Voelkel NF. Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats. American Journal of Respiratory and Critical Care Medicine. 182: 652-60. PMID 20508210 DOI: 10.1164/Rccm.201003-0335Oc  0.474
2010 Sakao S, Tatsumi K, Voelkel NF. Reversible or irreversible remodeling in pulmonary arterial hypertension. American Journal of Respiratory Cell and Molecular Biology. 43: 629-34. PMID 20008280 DOI: 10.1165/Rcmb.2009-0389Tr  0.548
2010 Flores S, Almodovar S, Voelkel N, Petrosillo N. Pulmonary hypertension associated with HIV-taskforce Pvri Review. 2: 42. DOI: 10.4103/0974-6013.58635  0.419
2009 Chen Y, Hanaoka M, Droma Y, Chen P, Voelkel NF, Kubo K. Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats. The European Respiratory Journal. 35: 904-12. PMID 19897563 DOI: 10.1183/09031936.00003909  0.325
2009 Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, Ockaili R, McCord JM, Voelkel NF. Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure. Circulation. 120: 1951-60. PMID 19884466 DOI: 10.1161/Circulationaha.109.883843  0.549
2009 Sakao S, Tatsumi K, Voelkel NF. Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation. Respiratory Research. 10: 95. PMID 19825167 DOI: 10.1186/1465-9921-10-95  0.531
2009 Hassoun PM, Mouthon L, Barberà JA, Eddahibi S, Flores SC, Grimminger F, Jones PL, Maitland ML, Michelakis ED, Morrell NW, Newman JH, Rabinovitch M, Schermuly R, Stenmark KR, Voelkel NF, et al. Inflammation, growth factors, and pulmonary vascular remodeling. Journal of the American College of Cardiology. 54: S10-9. PMID 19555853 DOI: 10.1016/J.Jacc.2009.04.006  0.479
2009 Voelkel NF, Spiegel S. Why is effective treatment of asthma so difficult? An integrated systems biology hypothesis of asthma. Immunology and Cell Biology. 87: 601-5. PMID 19546879 DOI: 10.1038/Icb.2009.45  0.344
2009 Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF. The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest. 135: 794-804. PMID 19265089 DOI: 10.1378/Chest.08-0492  0.521
2009 Chen Y, Hanaoka M, Chen P, Droma Y, Voelkel NF, Kubo K. Protective effect of beraprost sodium, a stable prostacyclin analog, in the development of cigarette smoke extract-induced emphysema. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L648-56. PMID 19201816 DOI: 10.1152/Ajplung.90270.2008  0.387
2009 Koff PB, Jones RH, Cashman JM, Voelkel NF, Vandivier RW. Proactive integrated care improves quality of life in patients with COPD. The European Respiratory Journal. 33: 1031-8. PMID 19129289 DOI: 10.1183/09031936.00063108  0.34
2009 Voelkel NF. Viral Infection and Pulmonary Endothelial Cells The Pulmonary Endothelium: Function in Health and Disease. 303-307. DOI: 10.1002/9780470747490.ch19  0.31
2008 Voelkel NF, Cool CD, Flores S. From viral infection to pulmonary arterial hypertension: a role for viral proteins? Aids (London, England). 22: S49-53. PMID 18845922 DOI: 10.1097/01.Aids.0000327516.55041.01  0.393
2008 Rai PR, Cool CD, King JA, Stevens T, Burns N, Winn RA, Kasper M, Voelkel NF. The cancer paradigm of severe pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 178: 558-64. PMID 18556624 DOI: 10.1164/Rccm.200709-1369Pp  0.506
2008 Ulrich S, Taraseviciene-Stewart L, Huber LC, Speich R, Voelkel N. Peripheral blood B lymphocytes derived from patients with idiopathic pulmonary arterial hypertension express a different RNA pattern compared with healthy controls: a cross sectional study. Respiratory Research. 9: 20. PMID 18269757 DOI: 10.1186/1465-9921-9-20  0.341
2008 Taraseviciene-Stewart L, Voelkel NF. Molecular pathogenesis of emphysema. The Journal of Clinical Investigation. 118: 394-402. PMID 18246188 DOI: 10.1172/Jci31811  0.37
2008 Daley E, Emson C, Guignabert C, de Waal Malefyt R, Louten J, Kurup VP, Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, Grunig G. Pulmonary arterial remodeling induced by a Th2 immune response. The Journal of Experimental Medicine. 205: 361-72. PMID 18227220 DOI: 10.1084/Jem.20071008  0.51
2008 Ofori-Acquah SF, King J, Voelkel N, Schaphorst KL, Stevens T. Heterogeneity of Barrier Function in the Lung Reflects Diversity in Endothelial Cell Junctions Microvascular Research. 75: 391-402. PMID 18068735 DOI: 10.1016/J.Mvr.2007.10.006  0.457
2008 Ulrich S, Nicolls MR, Taraseviciene L, Speich R, Voelkel N. Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension. Respiration. 75: 272-280. PMID 18025812 DOI: 10.1159/000111548  0.477
2008 Daley E, Emson C, Guignabert C, de Waal Malefyt R, Louten J, Kurup VP, Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, Grunig G. Pulmonary arterial remodeling induced by a Th2 immune response The Journal of Cell Biology. 180: i9-i9. DOI: 10.1083/JCB1803OIA9  0.308
2007 Babu AN, Murakawa T, Thurman JM, Miller EJ, Henson PM, Zamora MR, Voelkel NF, Nicolls MR. Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. The Journal of Clinical Investigation. 117: 3774-85. PMID 18060031 DOI: 10.1172/Jci32311  0.355
2007 Sakao S, Taraseviciene-Stewart L, Cool CD, Tada Y, Kasahara Y, Kurosu K, Tanabe N, Takiguchi Y, Tatsumi K, Kuriyama T, Voelkel NF. VEGF-R blockade causes endothelial cell apoptosis, expansion of surviving CD34+ precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3640-52. PMID 17567571 DOI: 10.1096/Fj.07-8432Com  0.391
2007 Taraseviciene-Stewart L, Nicolls MR, Kraskauskas D, Scerbavicius R, Burns N, Cool C, Wood K, Parr JE, Boackle SA, Voelkel NF. Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling. American Journal of Respiratory and Critical Care Medicine. 175: 1280-9. PMID 17413127 DOI: 10.1164/Rccm.200608-1189Oc  0.551
2007 Voelkel NF, Douglas IS, Nicolls M. Angiogenesis in chronic lung disease. Chest. 131: 874-9. PMID 17356107 DOI: 10.1378/Chest.06-2453  0.52
2007 Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circulation Research. 100: 923-9. PMID 17332430 DOI: 10.1161/01.Res.0000261658.12024.18  0.479
2007 Nana-Sinkam SP, Lee JD, Sotto-Santiago S, Stearman RS, Keith RL, Choudhury Q, Cool C, Parr J, Moore MD, Bull TM, Voelkel NF, Geraci MW. Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke. American Journal of Respiratory and Critical Care Medicine. 175: 676-85. PMID 17255567 DOI: 10.1164/Rccm.200605-724Oc  0.466
2007 Hoke TS, Douglas IS, Klein CL, He Z, Fang W, Thurman JM, Tao Y, Dursun B, Voelkel NF, Edelstein CL, Faubel S. Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury. Journal of the American Society of Nephrology : Jasn. 18: 155-64. PMID 17167117 DOI: 10.1681/Asn.2006050494  0.415
2007 Voelkel NF, Taraseviciene-Stewart L. Emphysema: An autoimmune vascular disease Endothelial Biomedicine. 1199-1201. DOI: 10.1017/CBO9780511546198.131  0.418
2007 Voelkel NF, Nicolls MR. The central role of endothelial cells in severe angioproliferative pulmonary hypertension Endothelial Biomedicine. 1193-1198. DOI: 10.1017/CBO9780511546198.130  0.435
2006 Taraseviciene-Stewart L, Douglas IS, Nana-Sinkam PS, Lee JD, Tuder RM, Nicolls MR, Voelkel NF. Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease? Proceedings of the American Thoracic Society. 3: 687-90. PMID 17065374 DOI: 10.1513/pats.200605-105SF  0.344
2006 Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, Dupuis J, Long CS, Rubin LJ, Smart FW, Suzuki YJ, Gladwin M, Denholm EM, Gail DB. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation. 114: 1883-91. PMID 17060398 DOI: 10.1161/Circulationaha.106.632208  0.418
2006 Golpon HA, Voelkel NF. The vasculature as a target in the treatment of pulmonary emphysema Current Drug Targets. 7: 737-741. PMID 16787175 DOI: 10.2174/138945006777435335  0.415
2006 Marecki JC, Cool CD, Parr JE, Beckey VE, Luciw PA, Tarantal AF, Carville A, Shannon RP, Cota-Gomez A, Tuder RM, Voelkel NF, Flores SC. HIV-1 Nef is associated with complex pulmonary vascular lesions in SHIV-nef-infected macaques. American Journal of Respiratory and Critical Care Medicine. 174: 437-45. PMID 16728715 DOI: 10.1164/Rccm.200601-005Oc  0.426
2006 Zimmermann R, Kreuder J, Michel-Behnke I, Voelkel NF, Schranz D. Pulmonary flow reserve in children with idiopathic pulmonary arterial hypertension: implications for diagnosis and therapy. European Journal of Medical Research. 11: 208-13. PMID 16723295  0.427
2006 Achcar RO, Yung GL, Saffer H, Cool CD, Voelkel NF, Yi ES. Morphologic changes in explanted lungs after prostacyclin therapy for pulmonary hypertension. European Journal of Medical Research. 11: 203-7. PMID 16723294  0.401
2006 Taraseviciute A, Voelkel NF. Severe pulmonary hypertension in postmenopausal obese women. European Journal of Medical Research. 11: 198-202. PMID 16723293  0.342
2006 Tayal S, Voelkel NF, Rai PR, Cool CD. Sarcoidois and pulmonary hypertension--a case report. European Journal of Medical Research. 11: 194-7. PMID 16723292  0.446
2006 Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Cool C, Wood K, Tuder RM, Burns N, Kasper M, Voelkel NF. Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L668-76. PMID 16698853 DOI: 10.1152/Ajplung.00491.2005  0.542
2006 Sakao S, Taraseviciene-Stewart L, Wood K, Cool CD, Voelkel NF. Apoptosis of pulmonary microvascular endothelial cells stimulates vascular smooth muscle cell growth. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L362-8. PMID 16617095 DOI: 10.1152/Ajplung.00111.2005  0.372
2006 Achcar RO, Demura Y, Rai PR, Taraseviciene-Stewart L, Kasper M, Voelkel NF, Cool CD. Loss of caveolin and heme oxygenase expression in severe pulmonary hypertension. Chest. 129: 696-705. PMID 16537870 DOI: 10.1378/Chest.129.3.696  0.435
2006 Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, et al. A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema. American Journal of Respiratory and Critical Care Medicine. 173: 1222-8. PMID 16514110 DOI: 10.1164/Rccm.200512-1842Oc  0.395
2006 Voelkel NF, Vandivier RW, Tuder RM. Vascular endothelial growth factor in the lung American Journal of Physiology - Lung Cellular and Molecular Physiology. 290. PMID 16403941 DOI: 10.1152/Ajplung.00185.2005  0.459
2006 Sakao S, Taraseviciene-Stewart L, Lee JD, Wood K, Cool CD, Voelkel NF. Vascular endothelial growth factor receptor blockade by SU5416 combined with pulsatile shear stress causes apoptosis and subsequent proliferation of apoptosis-resistant endothelial cells. Chest. 128: 610S-611S. PMID 16373861 DOI: 10.1378/Chest.128.6_Suppl.610S-A  0.313
2006 Bull TM, Coldren CD, Nana-Sinkam P, Sotto-Santiago SM, Moore M, Voelkel NF, Geraci MW. Microarray analysis of peripheral blood cells in pulmonary arterial hypertension, surrogate to biopsy. Chest. 128: 584S. PMID 16373849 DOI: 10.1378/Chest.128.6_Suppl.584S  0.479
2006 Douglas IS, Diaz Del Valle F, Winn RA, Voelkel NF. β-catenin in the fibroproliferative response to acute lung injury American Journal of Respiratory Cell and Molecular Biology. 34: 274-285. PMID 16272459 DOI: 10.1165/Rcmb.2005-0277Oc  0.379
2006 Nicolls MR, Tamosiuniene R, Voelkel NF. Inflammation in Pulmonary Hypertension: How Immunobiology Provides the Missing Link Between These Conditions Advances in Pulmonary Hypertension. 5: 26-29. DOI: 10.21693/1933-088X-5.3.26  0.421
2005 Vandivier RW, Voelkel NF. The challenges of chronic obstructive pulmonary diseases (COPD)--a perspective. Copd. 2: 177-84. PMID 17136979 DOI: 10.1081/Copd-200050676  0.386
2005 Sullivan A, Chmura K, Cool CD, Voelkel N, Chan ED. Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling in a fatal case. Chest. 128: 576S. PMID 16373838 DOI: 10.1378/chest.128.6_suppl.576S  0.388
2005 Sullivan A, Chmura K, Cool CD, Voelkel N, Chan ED. Pulmonary Capillary Hemangiomatosis Chest. 128: 267-273. PMID 16373837 DOI: 10.1378/Chest.128.6_Suppl.576S-A  0.541
2005 Lee JD, Taraseviciene-Stewart L, Keith R, Geraci MW, Voelkel NF. The expression of prostacyclin synthase is decreased in the small pulmonary arteries from patients with emphysema. Chest. 128: 575S. PMID 16373836 DOI: 10.1378/chest.128.6_suppl.575S  0.389
2005 Taraseviciene-Stewart L, Scerbavicius DK, Burns N, Cool CD, Nicolls MR, Voelkel NF. The protective role of T-lymphocytes in pulmonary vascular remodeling. Chest. 128: 571S-572S. PMID 16373829 DOI: 10.1378/Chest.128.6_Suppl.571S-A  0.329
2005 Cool CD, Groshong SD, Oakey J, Voelkel NF. Pulmonary hypertension: cellular and molecular mechanisms. Chest. 128: 565S-571S. PMID 16373828 DOI: 10.1378/Chest.128.6_Suppl.565S  0.404
2005 Nicolls MR, Taraseviciene-Stewart L, Rai PR, Badesch DB, Voelkel NF. Autoimmunity and pulmonary hypertension: a perspective. The European Respiratory Journal. 26: 1110-8. PMID 16319344 DOI: 10.1183/09031936.05.00045705  0.542
2005 Voelkel N, Taraseviciene-Stewart L. Emphysema: an autoimmune vascular disease? Proceedings of the American Thoracic Society. 2: 23-5. PMID 16113465 DOI: 10.1513/pats.200405-033MS  0.317
2005 Majka SM, Beutz MA, Hagen M, Izzo AA, Voelkel N, Helm KM. Identification of novel resident pulmonary stem cells: form and function of the lung side population. Stem Cells (Dayton, Ohio). 23: 1073-81. PMID 15987674 DOI: 10.1634/Stemcells.2005-0039  0.405
2005 Sullivan AK, Simonian PL, Falta MT, Mitchell JD, Cosgrove GP, Brown KK, Kotzin BL, Voelkel NF, Fontenot AP. Oligoclonal CD4+ T cells in the lungs of patients with severe emphysema. American Journal of Respiratory and Critical Care Medicine. 172: 590-6. PMID 15937291 DOI: 10.1164/Rccm.200410-1332Oc  0.342
2005 Sakao S, Taraseviciene-Stewart L, Lee JD, Wood K, Cool CD, Voelkel NF. Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1178-80. PMID 15897232 DOI: 10.1096/Fj.04-3261Fje  0.371
2005 Taraseviciene-Stewart L, Scerbavicius R, Stewart JM, Gera L, Demura Y, Cool C, Kasper M, Voelkel NF. Treatment of severe pulmonary hypertension: a bradykinin receptor 2 agonist B9972 causes reduction of pulmonary artery pressure and right ventricular hypertrophy. Peptides. 26: 1292-300. PMID 15878794 DOI: 10.1016/J.Peptides.2005.03.050  0.532
2005 Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Moore M, Sullivan A, Nicolls MR, Fontenot AP, Tuder RM, Voelkel NF. An animal model of autoimmune emphysema. American Journal of Respiratory and Critical Care Medicine. 171: 734-42. PMID 15563631 DOI: 10.1164/Rccm.200409-1275Oc  0.329
2005 Tuder RM, Voelkel NF, Fagan KA. Cellular and Molecular Mechanisms of Pulmonary Hypertension Beyond Vasodilators Chest. 128: 1E-2E. DOI: 10.1378/Chest.128.6_Suppl.E1S  0.508
2005 Lee JD, Taraseviciene-Stewart L, Keith R, Geraci MW, Voelkel NF. The Expression of Prostacyclin Synthase Is Decreased in the Small Pulmonary Arteries From Patients With Emphysema Chest. 128: 575S. DOI: 10.1016/S0012-3692(15)30992-2  0.496
2004 Demura Y, Taraseviciene-Stewart L, Scerbavicius R, Tuder RM, Voelkel NF. N-acetylcysteine treatment protects against VEGF-receptor blockade-related emphysema. Copd. 1: 25-32. PMID 16997736 DOI: 10.1081/Copd-120030412  0.396
2004 Voelkel NF, Agusti A. COPD at the 2004 9th European Pulmonary Summit Pulmonary Pharmacology and Therapeutics. 17: 249-251. PMID 15477119 DOI: 10.1016/J.Pupt.2004.05.001  0.465
2004 Richter A, Yeager ME, Zaiman A, Cool CD, Voelkel NF, Tuder RM. Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 170: 1340-8. PMID 15361368 DOI: 10.1164/Rccm.200311-1602Oc  0.522
2004 Voelkel NF, Cool C. Pathology of pulmonary hypertension Cardiology Clinics. 22: 343-351. PMID 15302355 DOI: 10.1016/J.Ccl.2004.04.010  0.449
2004 Bull TM, Coldren CD, Moore M, Sotto-Santiago SM, Pham DV, Nana-Sinkam SP, Voelkel NF, Geraci MW. Gene microarray analysis of peripheral blood cells in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 170: 911-9. PMID 15215156 DOI: 10.1164/Rccm.200312-1686Oc  0.442
2004 Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, McGoon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, ... ... Voelkel NF, et al. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 109: 2947-52. PMID 15210611 DOI: 10.1161/01.Cir.0000132476.87231.6F  0.518
2004 Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M. Cellular and molecular pathobiology of pulmonary arterial hypertension. Journal of the American College of Cardiology. 43: 13S-24S. PMID 15194174 DOI: 10.1016/J.Jacc.2004.02.029  0.559
2004 Voelkel NF. A conference report. The Second Siena International Conference on animal models of chronic obstructive pulmonary disease Pulmonary Pharmacology and Therapeutics. 17: 61-63. PMID 15125496 DOI: 10.1016/j.pupt.2003.10.007  0.327
2004 Tuder RM, McGrath S, Voelkel NF, Geraci MW. Oxygen-Dependent Regulation of Pulmonary Circulation Methods in Enzymology. 381: 87-106. PMID 15063667 DOI: 10.1016/S0076-6879(04)81005-X  0.536
2004 Bowers R, Cool C, Murphy RC, Tuder RM, Hopken MW, Flores SC, Voelkel NF. Oxidative stress in severe pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 169: 764-9. PMID 14701708 DOI: 10.1164/Rccm.200301-147Oc  0.311
2004 Voelkel NF, Taraseviciene-Stewart L, Tuder R. Emphysema - A vascular disease? Drug Discovery Today: Disease Mechanisms. 1: 145-149. DOI: 10.1016/J.Ddmec.2004.08.010  0.345
2003 Voelkel NF, Cool CD. Pulmonary vascular involvement in chronic obstructive pulmonary disease European Respiratory Journal, Supplement. 22. PMID 14621104 DOI: 10.1183/09031936.03.00000503  0.526
2003 Bull TM, Cool CD, Serls AE, Rai PR, Parr J, Neid JM, Geraci MW, Campbell TB, Voelkel NF, Badesch DB. Primary pulmonary hypertension, Castleman's disease and human herpesvirus-8. The European Respiratory Journal. 22: 403-7. PMID 14516126 DOI: 10.1183/09031936.03.00006903  0.408
2003 Bull TM, Golpon H, Hebbel RP, Solovey A, Cool CD, Tuder RM, Geraci MW, Voelkel NF. Circulating endothelial cells in pulmonary hypertension. Thrombosis and Haemostasis. 90: 698-703. PMID 14515191 DOI: 10.1160/Th03-04-0251  0.566
2003 Cool CD, Rai PR, Yeager ME, Hernandez-Saavedra D, Serls AE, Bull TM, Geraci MW, Brown KK, Routes JM, Tuder RM, Voelkel NF. Expression of human herpesvirus 8 in primary pulmonary hypertension. The New England Journal of Medicine. 349: 1113-22. PMID 13679525 DOI: 10.1056/Nejmoa035115  0.464
2003 Ameshima S, Golpon H, Cool CD, Chan D, Vandivier RW, Gardai SJ, Wick M, Nemenoff RA, Geraci MW, Voelkel NF. Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth. Circulation Research. 92: 1162-9. PMID 12714563 DOI: 10.1161/01.Res.0000073585.50092.14  0.494
2003 Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. American Journal of Respiratory Cell and Molecular Biology. 28: 551-4. PMID 12707010 DOI: 10.1165/Rcmb.F269  0.339
2003 Abraham WT, Raynolds MV, Badesch DB, Wynne KM, Groves BM, Roden RL, Robertson AD, Lowes BD, Zisman LS, Voelkel NF, Bristow MR, Perryman MB. Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: Increased frequency and association with preserved haemodynamics Jraas - Journal of the Renin-Angiotensin-Aldosterone System. 4: 27-30. PMID 12692750 DOI: 10.3317/Jraas.2003.003  0.417
2003 Tuder RM, Zhen L, Cho CY, Taraseviciene-Stewart L, Kasahara Y, Salvemini D, Voelkel NF, Flores SC. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. American Journal of Respiratory Cell and Molecular Biology. 29: 88-97. PMID 12600822 DOI: 10.1165/Rcmb.2002-0228Oc  0.387
2003 Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Gera L, Tuder RM, Voelkel NF. Methylprednisolone causes matrix metalloproteinase-dependent emphysema in adult rats. American Journal of Respiratory and Critical Care Medicine. 167: 1516-21. PMID 12522028 DOI: 10.1164/Rccm.200210-1207Oc  0.42
2003 Hoshikawa Y, Nana-Sinkam P, Moore MD, Sotto-Santiago S, Phang T, Keith RL, Morris KG, Kondo T, Tuder RM, Voelkel NF, Geraci MW. Hypoxia induces different genes in the lungs of rats compared with mice. Physiological Genomics. 12: 209-19. PMID 12464684 DOI: 10.1152/Physiolgenomics.00081.2001  0.463
2003 Voelkel NF, Taraseviciene-Stewart L, Cool C. Severe Angioproliferative Pulmonary Hypertension: The Lung Circulation Between Vasoconstriction and Cancer Advances in Pulmonary Hypertension. 2: 4-8. DOI: 10.21693/1933-088X-2.4.4  0.423
2003 Nana-Sinkam SP, Golpon H, Keith RL, Moore MD, Voelkel NF, Franklin W, Miller YE, Nemenoff RA, Geraci MW. O-301 Prostacyclin in human non-small cell lung cancers and regulatory mechanisms Lung Cancer. 41: S88. DOI: 10.1016/S0169-5002(03)91959-3  0.307
2002 Tuder RM, Voelkel NF. Angiogenesis and pulmonary hypertension: A unique process in a unique disease Antioxidants and Redox Signaling. 4: 833-843. PMID 12470512 DOI: 10.1089/152308602760598990  0.569
2002 Le Cras TD, Markham NE, Tuder RM, Voelkel NF, Abman SH. Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure American Journal of Physiology - Lung Cellular and Molecular Physiology. 283: L555-L562. PMID 12169575 DOI: 10.1152/Ajplung.00408.2001  0.527
2002 Taraseviciene-Stewart L, Gera L, Hirth P, Voelkel NF, Tuder RM, Stewart JM. A bradykinin antagonist and a caspase inhibitor prevent severe pulmonary hypertension in a rat model. Canadian Journal of Physiology and Pharmacology. 80: 269-74. PMID 12025960 DOI: 10.1139/Y02-047  0.498
2002 Voelkel NF. High-altitude pulmonary edema New England Journal of Medicine. 346: 1606-1607. PMID 12023991 DOI: 10.1056/Nejm199603073341013  0.445
2002 Voelkel NF, Cool C, Taraceviene-Stewart L, Geraci MW, Yeager M, Bull T, Kasper M, Tuder RM. Janus face of vascular endothelial growth factor: the obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Critical Care Medicine. 30: S251-6. PMID 12004244 DOI: 10.1097/00003246-200205001-00013  0.526
2002 Geraci MW, Hoshikawa Y, Yeager M, Golpon H, Gesell T, Tuder RM, Voelkel NF. Gene expression profiles in pulmonary hypertension. Chest. 121: 104S-105S. PMID 11893725 DOI: 10.1378/Chest.121.3_Suppl.104S  0.475
2002 Yeager ME, Golpon HA, Voelkel NF, Tuder RM. Microsatellite mutational analysis of endothelial cells within plexiform lesions from patients with familial, pediatric, and sporadic pulmonary hypertension. Chest. 121: 61S. PMID 11893687 DOI: 10.1378/Chest.121.3_Suppl.61S  0.413
2002 Tuder RM, Cool CD, Yeager M, Taraseviciene-Stewart L, Bull TM, Voelkel NF. The pathobiology of pulmonary hypertension. Endothelium. Clinics in Chest Medicine. 22: 405-18. PMID 11590837 DOI: 10.1016/S0272-5231(05)70280-X  0.526
2002 Voelkel NF, Page C. The COPD corner Pulmonary Pharmacology and Therapeutics. 15: 339. DOI: 10.1006/Pupt.2002.0379  0.391
2001 Geraci MW, Gao B, Hoshikawa Y, Yeager ME, Tuder RM, Voelkel NF. Genomic approaches to research in pulmonary hypertension. Respiratory Research. 2: 210-5. PMID 11686886 DOI: 10.1186/Rr59  0.351
2001 Tuder RM, Chacon M, Alger L, Wang J, Taraseviciene-Stewart L, Kasahara Y, Cool CD, Bishop AE, Geraci M, Semenza GL, Yacoub M, Polak JM, Voelkel NF. Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis. The Journal of Pathology. 195: 367-74. PMID 11673836 DOI: 10.1002/Path.953  0.456
2001 Tuder RM, Yeager ME, Geraci M, Golpon HA, Voelkel NF. Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene. The European Respiratory Journal. 17: 1065-9. PMID 11491145 DOI: 10.1183/09031936.01.00202701  0.541
2001 Hoshikawa Y, Voelkel NF, Gesell TL, Moore MD, Morris KG, Alger LA, Narumiya S, Geraci MW. Prostacyclin receptor-dependent modulation of pulmonary vascular remodeling. American Journal of Respiratory and Critical Care Medicine. 164: 314-8. PMID 11463607 DOI: 10.1164/Ajrccm.164.2.2010150  0.535
2001 Tuder RM, Voelkel NF. Plexiform lesion in severe pulmonary hypertension: association with glomeruloid lesion American Journal of Pathology. 159: 382-383. PMID 11438486 DOI: 10.1016/S0002-9440(10)61705-1  0.375
2001 Geraci MW, Moore M, Gesell T, Yeager ME, Alger L, Golpon H, Gao B, Loyd JE, Tuder RM, Voelkel NF. Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis. Circulation Research. 88: 555-62. PMID 11282888 DOI: 10.1161/01.Res.88.6.555  0.45
2001 Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. American Journal of Respiratory and Critical Care Medicine. 163: 737-44. PMID 11254533 DOI: 10.1164/Ajrccm.163.3.2002117  0.441
2001 Hoshikawa Y, Ono S, Suzuki S, Tanita T, Chida M, Song C, Noda M, Tabata T, Voelkel NF, Fujimura S. Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia. Journal of Applied Physiology. 90: 1299-1306. PMID 11247927 DOI: 10.1152/Jappl.2001.90.4.1299  0.519
2001 Golpon HA, Geraci MW, Moore MD, Miller HL, Miller GJ, Tuder RM, Voelkel NF. HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema. The American Journal of Pathology. 158: 955-66. PMID 11238043 DOI: 10.1016/S0002-9440(10)64042-4  0.445
2001 Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 427-38. PMID 11156958 DOI: 10.1096/Fj.00-0343Com  0.578
2001 Yeager ME, Halley GR, Golpon HA, Voelkel NF, Tuder RM. Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension. Circulation Research. 88: E2-E11. PMID 11139485 DOI: 10.1161/01.Res.88.1.E2  0.361
2001 Lee SD, Lee DS, Chun YG, Paik SH, Kim WS, Kim DS, Kim WD, Tuder RM, Voelkel NF. Transforming growth factor-beta1 induces endothelin-1 in a bovine pulmonary artery endothelial cell line and rat lungs via cAMP. Pulmonary Pharmacology & Therapeutics. 13: 257-65. PMID 11061980 DOI: 10.1006/Pupt.2000.0252  0.326
2000 Kasahara Y, Tuder RM, Taraseviciene-Stewart L, Le Cras TD, Abman S, Hirth PK, Waltenberger J, Voelkel NF. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema Journal of Clinical Investigation. 106: 1311-1319. PMID 11104784 DOI: 10.1172/Jci10259  0.475
2000 Voelkel NF, Tuder RM. Hypoxia-induced pulmonary vascular remodeling: A model for what human disease? Journal of Clinical Investigation. 106: 733-738. PMID 10995781 DOI: 10.1172/Jci11144  0.548
2000 Jakkula M, Le Cras TD, Gebb S, Hirth KP, Tuder RM, Voelkel NF, Abman SH. Inhibition of angiogenesis decreases alveolarization in the developing rat lung American Journal of Physiology - Lung Cellular and Molecular Physiology. 279: L600-L607. PMID 10956636 DOI: 10.1152/Ajplung.2000.279.3.L600  0.468
2000 Voelkel MA, Wynne KM, Badesch DB, Groves BM, Voelkel NF. Hyperuricemia in severe pulmonary hypertension Chest. 117: 19-24. PMID 10631193 DOI: 10.1378/Chest.117.1.19  0.471
2000 Kasahara Y, Tuder RM, Cool CD, Voelkel NF. Expression of 15-lipoxygenase and evidence for apoptosis in the lungs from patients with COPD Chest. 117. DOI: 10.1378/Chest.117.5_Suppl_1.260S  0.407
2000 Tuder RM, Kasahara Y, Voelkel NF. Inhibition of vascular endothelial growth factor receptors causes emphysema in rats Chest. 117. DOI: 10.1016/S0012-3692(15)51033-7  0.337
1999 Voelkel NF, Tuder RM. Severe pulmonary hypertensive diseases: A perspective European Respiratory Journal. 14: 1246-1250. PMID 10624750 DOI: 10.1183/09031936.99.14612469  0.516
1999 Cool CD, Stewart JS, Werahera P, Miller GJ, Williams RL, Voelkel NF, Tuder RM. Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth. The American Journal of Pathology. 155: 411-9. PMID 10433934 DOI: 10.1016/S0002-9440(10)65137-1  0.459
1999 Ishizaki T, Ozawa T, Voelkel NF. Leukotoxins and the lung Pulmonary Pharmacology and Therapeutics. 12: 145-155. PMID 10419834 DOI: 10.1006/Pupt.1999.0179  0.375
1999 Geraci MW, Gao B, Shepherd DC, Moore MD, Westcott JY, Fagan KA, Alger LA, Tuder RM, Voelkel NF. Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension. The Journal of Clinical Investigation. 103: 1509-15. PMID 10359560 DOI: 10.1172/Jci5911  0.516
1999 Tuder RM, Cool CD, Geraci MW, Wang J, Abman SH, Wright L, Badesch D, Voelkel NF. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension American Journal of Respiratory and Critical Care Medicine. 159: 1925-1932. PMID 10351941 DOI: 10.1164/Ajrccm.159.6.9804054  0.509
1999 Voelkel NF, Allard JD, Anderson SM, Burke TJ. cGMP and cAMP cause pulmonary vasoconstriction in the presence of hemolysate Journal of Applied Physiology. 86: 1715-1720. PMID 10233139 DOI: 10.1152/Jappl.1999.86.5.1715  0.438
1999 Quaife RA, Lynch D, Badesch DB, Voelkel NF, Lowes BD, Robertson AD, Bristow MR. Right ventricular phenotypic characteristics in subjects with primary pulmonary hypertension or idiopathic dilated cardiomyopathy Journal of Cardiac Failure. 5: 46-54. PMID 10194660 DOI: 10.1016/S1071-9164(99)90024-6  0.396
1999 Tuder RM, Radisavljevic Z, Shroyer KR, Polak JM, Voelkel NF. Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 158: 1999-2001. PMID 9847298 DOI: 10.1164/Ajrccm.158.6.9805002  0.468
1998 Voelkel NF, Cool C, Lee SD, Wright L, Geraci MW, Tuder RM. Primary pulmonary hypertension between inflammation and cancer. Chest. 114: 225S-230S. PMID 9741573 DOI: 10.1378/Chest.114.3_Supplement.225S  0.515
1998 Bristow MR, Zisman LS, Lowes BD, Abraham WT, Badesch DB, Groves BM, Voelkel NF, Lynch DMB, Quaife RA. The pressure-overloaded right ventricle in pulmonary hypertension Chest. 114: 101S-106S. PMID 9676654 DOI: 10.1378/Chest.114.1_Supplement.101S  0.379
1998 Geraci M, Gao B, Shepherd D, Allard J, Curiel D, Westcott J, Voelkel N. Pulmonary prostacyclin synthase overexpression by adenovirus transfection and in transgenic mice. Chest. 114: 99S. PMID 9676651 DOI: 10.1378/Chest.114.1_Supplement.99S  0.398
1998 Cohen AJ, Cool C, Gorg S, Gilman LB, Tuder RM, Miller YE, Voelkel NF. Low or absent peptidase expression in plexiform lesions of primary pulmonary hypertension. Chest. 114: 30S-31S. PMID 9676613 DOI: 10.1378/Chest.114.1_Supplement.30S  0.449
1998 Tuder RM, Voelkel NF. Pulmonary hypertension and inflammation Journal of Laboratory and Clinical Medicine. 132: 16-24. PMID 9665367 DOI: 10.1016/S0022-2143(98)90020-8  0.543
1998 Silliman CC, Voelkel NF, Allard JD, Elzi DJ, Tuder RM, Johnson JL, Ambruso DR. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. The Journal of Clinical Investigation. 101: 1458-67. PMID 9525989 DOI: 10.1172/Jci1841  0.373
1998 Lee SD, Shroyer KR, Markham NE, Cool CD, Voelkel NF, Tuder RM. Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. The Journal of Clinical Investigation. 101: 927-34. PMID 9486960 DOI: 10.1172/Jci1910  0.457
1998 Wright L, Tuder RM, Wang J, Cool CD, Lepley RA, Voelkel NF. 5-Lipoxygenase and 5-lipoxygenase activating protein (FLAP) immunoreactivity in lungs from patients with primary pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 157: 219-29. PMID 9445303 DOI: 10.1164/Ajrccm.157.1.9704003  0.506
1998 Höper MM, Voelkel NF, Bates TO, Allard JD, Horan M, Shepherd D, Tuder RM. Prostaglandins induce vascular endothelial growth factor in a human monocytic cell line and rat lungs via cAMP. American Journal of Respiratory Cell and Molecular Biology. 17: 748-56. PMID 9409562 DOI: 10.1165/Ajrcmb.17.6.2888  0.397
1998 Voelkel NF. Introduction: Biology and pathobiology of the lung circulation Chest. 114. DOI: 10.1378/Chest.114.1_Supplement.1S  0.391
1997 Voelkel NF, Tuder RM. Cellular and molecular biology of vascular smooth muscle cells in pulmonary hypertension Pulmonary Pharmacology and Therapeutics. 10: 231-241. PMID 9778486 DOI: 10.1006/Pupt.1998.0100  0.457
1997 Lowes BD, Minobe W, Abraham WT, Rizeq MN, Bohlmeyer TJ, Quaife RA, Roden RL, Dutcher DL, Robertson AO, Voelkel NF, Badesch DB, Groves BM, Gilbert EM, Bristow MR. Changes in gene expression in the intact human heart: Downregulation of α-myosin heavy chain in hypertrophied, failing ventricular myocardium Journal of Clinical Investigation. 100: 2315-2324. PMID 9410910 DOI: 10.1172/Jci119770  0.319
1997 Voelkel NF. Appetite suppressants and pulmonary hypertension Thorax. 52. PMID 9381430  0.449
1997 Geraci M, Shepherd D, Moore M, Vernon J, Allard J, Shannon J, Voelkel NF. Rat prostacyclin synthase. Cloning and regulation of gene expression in the lung. Chest. 111: 129S. PMID 9184561 DOI: 10.1378/Chest.111.6_Supplement.129S  0.364
1997 Voelkel NF, Clarke WR, Higenbottam T. Obesity, dexfenfluramine, and pulmonary hypertension: A lesson not learned? American Journal of Respiratory and Critical Care Medicine. 155: 786-788. PMID 9117009 DOI: 10.1164/Ajrccm.155.3.9117009  0.386
1997 Cool CD, Kennedy D, Voelkel NF, Tuder RM. Pathogenesis and evolution of plexiform lesions in pulmonary hypertension associated with scleroderma and human immunodeficiency virus infection Human Pathology. 28: 434-442. PMID 9104943 DOI: 10.1016/S0046-8177(97)90032-0  0.382
1996 Chida M, Voelkel NF. Effects of acute and chronic hypoxia on rat lung cyclooxygenase American Journal of Physiology - Lung Cellular and Molecular Physiology. 270. PMID 8967523  0.329
1996 Voelkel NF, Hoeper M, Maloney J, Tuder RM. Vascular endothelial growth factor in pulmonary hypertension Annals of the New York Academy of Sciences. 796: 186-193. PMID 8906225 DOI: 10.1111/J.1749-6632.1996.Tb32580.X  0.484
1996 Voelkel NF. Drug-induced pulmonary hypertension: Must history repeat itself? Pulmonary Pharmacology. 9: 67-68. PMID 8880947 DOI: 10.1006/Pulp.1996.0009  0.48
1996 Ishizaki T, Shigemori K, Ameshima S, Nakai T, Miyabo S, Hayakawa M, Ozawa T, Voelkel NF. Protective effects of BQ-123, an ETA receptor antagonist, against leukotoxin-induced injury in rat lungs American Journal of Physiology-Lung Cellular and Molecular Physiology. 271. PMID 8843795 DOI: 10.1152/Ajplung.1996.271.3.L459  0.365
1996 Voelkel NF, Tuder RM, Wade K, Höper M, Lepley RA, Goulet JL, Koller BH, Fitzpatrick F. Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats. The Journal of Clinical Investigation. 97: 2491-8. PMID 8647941 DOI: 10.1172/Jci118696  0.573
1995 Voelkel NF, Tuder RM. Cellular and molecular mechanisms in the pathogenesis of severe pulmonary hypertension European Respiratory Journal. 8: 2129-2138. PMID 8666110 DOI: 10.1183/09031936.95.08122129  0.552
1995 Chida M, Voelkel NF, Ono S, Tanita T, Fujimura S. Leukocyte-mediated production of eicosanoids in rat lungs: Modulation by a calcium antagonist Japanese Journal of Thoracic Diseases. 33: 1198-1203. PMID 8583710  0.325
1995 Ishizaki T, Shigemori K, Nakai T, Miyabo S, Hayakawa M, Ozawa T, Voelkel NF, Chang S. Endothelin-1 potentiates leukotoxin-induced edematous lung injury. Journal of Applied Physiology. 79: 1106-1111. PMID 8567550 DOI: 10.1152/Jappl.1995.79.4.1106  0.432
1995 Voelkel NF, Lobel K, Westcott JY, Burke TJ. Nitric oxide-related vasoconstriction in lungs perfused with red cell lysate Faseb Journal. 9: 379-386. PMID 7896007 DOI: 10.1096/Fasebj.9.5.7896007  0.413
1995 Ishizaki T, Takahashi H, Ozawa T, Chang SW, Voelkel NF. Leukotoxin, 9,10-epoxy-12-octadecenoate causes pulmonary vasodilation in rats American Journal of Physiology - Lung Cellular and Molecular Physiology. 268. PMID 7840218 DOI: 10.1152/Ajplung.1995.268.1.L123  0.483
1995 Ishizaki T, Shigemori K, Yamamura Y, Matsukawa S, Nakai T, Miyabo S, Hayakawa M, Ozawa T, Voelkel NF. Increased nitric oxide biosynthesis in leukotoxin,9,10-epoxy-12-octadecenoate injured lung. Biochemical and Biophysical Research Communications. 210: 133-137. PMID 7741732 DOI: 10.1006/Bbrc.1995.1637  0.377
1995 Tuder RM, Flook BE, Voelkel NF. Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia: Modulation of gene expression by nitric oxide Journal of Clinical Investigation. 95: 1798-1807. PMID 7706486 DOI: 10.1172/Jci117858  0.443
1995 Abraham WT, Raynolds MV, Gottschall B, Badesch DB, Wynne KM, Groves BM, Lowes BD, Bristow MR, Perryman MB, Voelkel NF. Importance of angiotensin-converting enzyme in pulmonary hypertension Cardiology (Switzerland). 86: 9-15. PMID 7614507 DOI: 10.1159/000176939  0.552
1995 Ishizaki T, Shigemori K, Nakai T, Miyabo S, Ozawa T, Chang SW, Voelkel NF. Leukotoxin, 9,10-epoxy-12-octadecenoate causes edematous lung injury via activation of vascular nitric oxide synthase American Journal of Physiology-Lung Cellular and Molecular Physiology. 269. PMID 7543250 DOI: 10.1152/Ajplung.1995.269.1.L65  0.48
1995 Abraham WT, Raynolds MV, Badesch DB, Lowes BD, Groves BM, Wynne KM, Voelkel NF, Perryman MB, Bristow MR. 901-94 The Angiotensin Converting Enzyme DD Genotype is Associated with Preserved Right Ventricular Function in Patients with Severe Primary Pulmonary Hypertension Journal of the American College of Cardiology. 25: 27A-28A. DOI: 10.1016/0735-1097(95)91571-E  0.345
1994 Fisher J, Badesch DB, Voelkel NF, Groves BM. Hypothyroidism and primary pulmonary hypertension [6] Annals of Internal Medicine. 120: 167-168. PMID 8256982  0.431
1994 Chen CR, Voelkel NF, Chang SW. Platelet-activating Factor Potentiates Protamine-induced Lung Edema Role of Eicosanoids American Journal of Respiratory and Critical Care Medicine. 149: 34-40. PMID 8111595  0.361
1994 Muskardin DT, Voelkel NF, Fitzpatrick FA. Modulation of pulmonary leukotriene formation and perfusion pressure by bestatin, an inhibitor of leukotriene A4 hydrolase. Biochemical Pharmacology. 48: 131-7. PMID 8043014 DOI: 10.1016/0006-2952(94)90232-1  0.399
1994 Voelkel NF, Tuder R. Interleukin-1 receptor antagonist inhibits pulmonary hypertension induced by inflammation Annals of the New York Academy of Sciences. 725: 104-109. PMID 8030981 DOI: 10.1111/J.1749-6632.1994.Tb39794.X  0.477
1994 Voelkel NF, Tuder RM, Bridges J, Arend WP. Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline American Journal of Respiratory Cell and Molecular Biology. 11: 664-675. PMID 7946395 DOI: 10.1165/Ajrcmb.11.6.7946395  0.444
1994 Badesch DB, Voelkel NF, Groves BM. Hypothyroidism and Primary Pulmonary Hypertension Annals of Internal Medicine. 120: 167-168. DOI: 10.7326/0003-4819-120-2-199401150-00021  0.524
1994 Groves B, Badesch D, Donnellan K, Wynne K, Robertson A, Voelkel N, Dole W, Reeves J. Acute Hemodynamic Effects of Iloprost in Primary (Unexplained) Pulmonary Hypertension Seminars in Respiratory and Critical Care Medicine. 15: 230-237. DOI: 10.1055/S-2007-1006367  0.518
1994 Voelkel NF. Pulmonary hypertension: Part II. Preface Seminars in Respiratory and Critical Care Medicine. 15.  0.384
1993 Badesch DB, Wynne KM, Bonvallet S, Voelkel NF, Ridgway C, Groves BM. Hypothyroidism and primary pulmonary hypertension: an autoimmune pathogenetic link? Annals of Internal Medicine. 119: 44-6. PMID 8498763 DOI: 10.7326/0003-4819-119-1-199307010-00008  0.484
1993 Ono S, Westcott JY, Chang SW, Voelkel NF. Endotoxin priming followed by high altitude causes pulmonary edema in rats Journal of Applied Physiology. 74: 1534-1542. PMID 8390437  0.394
1993 Westcott JY, Voelkel NF, Jones K, Wenzel SE. Inactivation of leukotriene C4 in the airways and subsequent urinary leukotriene E4 excretion in normal and asthmatic subjects American Review of Respiratory Disease. 148: 1244-1251. PMID 7694531 DOI: 10.1164/Ajrccm/148.5.1244  0.338
1992 Jones DK, Perry EM, Grosso MA, Voelkel NF. Release of von Willebrand factor antigen (vWF:Ag) and eicosanoids during acute injury to the isolated rat lung American Review of Respiratory Disease. 145: 1410-1415. PMID 1596010 DOI: 10.1164/Ajrccm/145.6.1410  0.416
1992 Chang SW, Czartolomna J, Voelkel NF. Role of eicosanoids in staphylococcal α-toxin-induced lung injury in the rat American Journal of Physiology - Lung Cellular and Molecular Physiology. 262. PMID 1566864 DOI: 10.1152/Ajplung.1992.262.4.L502  0.378
1992 Voelkel NF, Czartolomna J, Simpson J, Murphy RC. FMLP causes eicosanoid-dependent vasoconstriction and edema in lungs from endotoxin-primed rats American Review of Respiratory Disease. 145: 701-711. PMID 1546853 DOI: 10.1164/Ajrccm/145.3.701  0.448
1992 Gottschall EB, Fernyak S, Wuertemberger G, Voelkel NF. Almitrine mimics hypoxic vasoconstriction in isolated rat lungs American Journal of Physiology - Heart and Circulatory Physiology. 263. PMID 1510135 DOI: 10.1152/Ajpheart.1992.263.2.H383  0.545
1992 Chen CR, Voelkel NF, Chang SW. Pulmonary vascular reactivity: Effect of PAF and PAF antagonists Journal of Applied Physiology. 73: 1762-1769. PMID 1474049  0.425
1992 Chang SW, Dutton D, Wang HL, He LS, Stearns R, Hui A, Giacomini KM, Ortiz de Montellano P, Voelkel NF. Intact lung cytochrome P-450 is not required for hypoxic pulmonary vasoconstriction. The American Journal of Physiology. 263: L446-53. PMID 1415722 DOI: 10.1152/Ajplung.1992.263.4.L446  0.474
1992 Ono S, WestCott JY, Voelkel NF. PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats Journal of Applied Physiology. 73: 1084-1092. PMID 1400021  0.467
1992 Ono S, Voelkel NF. PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model Lung: An International Journal On Lungs, Airways and Breathing. 170: 31-40. PMID 1310128 DOI: 10.1007/Bf00164753  0.534
1991 He L, Chang SW, Voelkel NF. Pulmonary vascular reactivity in Fischer rats Journal of Applied Physiology. 70: 1861-1866. PMID 2055865 DOI: 10.1152/Jappl.1991.70.4.1861  0.468
1991 Czartolomna J, Voelkel NF, Chang SW. Permeability characteristics of isolated perfused rat lungs Journal of Applied Physiology. 70: 1854-1860. PMID 2055864 DOI: 10.1152/Jappl.1991.70.4.1854  0.423
1991 Stenmark KR, Aldashev AA, Orton EC, Durmowicz AG, Badesch DB, Parks WC, Mecham RP, Voelkel NF, Reeves JT. Cellular adaptation during chronic neonatal hypoxic pulmonary hypertension. The American Journal of Physiology. 261: 97-104. PMID 1928459 DOI: 10.1152/Ajpheart.1991.261.4.97  0.485
1991 Ono S, Voelkel NF. PAF antagonists inhibit monocrotaline-induced lung injury and pulmonary hypertension Journal of Applied Physiology. 71: 2483-2492. PMID 1838107  0.49
1991 Sala A, Murphy RC, Voelkel NF. Direct airway injury results in elevated levels of sulfidopeptide leukotrienes, detectable in airway secretions Prostaglandins. 42: 1-7. PMID 1771235 DOI: 10.1016/0090-6980(91)90088-W  0.332
1990 Graham LM, Vasil A, Vasil ML, Voelkel NF, Stenmark KR. Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia American Review of Respiratory Disease. 142: 221-229. PMID 2368972 DOI: 10.1164/Ajrccm/142.1.221  0.423
1990 Dempsey EC, Stenmark KR, McMurtry IF, O'Brien RF, Voelkel NF, Badesch DB. Insulin-like growth factor I and protein kinase C activation stimulate pulmonary artery smooth muscle cell proliferation through separate but synergistic pathways Journal of Cellular Physiology. 144: 159-165. PMID 2365741 DOI: 10.1002/Jcp.1041440121  0.398
1990 Chen CR, Voelkel NF, Chang SW. PAF potentiates protamine-induced lung edema: Role of pulmonary venoconstriction Journal of Applied Physiology. 68: 1059-1068. PMID 2341334  0.37
1990 Chang SW, Fernyak S, Voelkel NF. Beneficial effect of a platelet-activating factor antagonist, WEB 2086, on endotoxin-induced lung injury American Journal of Physiology - Heart and Circulatory Physiology. 258. PMID 2301603 DOI: 10.1152/Ajpheart.1990.258.1.H153  0.361
1990 He L, Chang SW, Ortiz De Montellano P, Burke TJ, Voelkel NF. Lung injury in Fischer but not Sprague-Dawley rats after short-term hyperoxia American Journal of Physiology - Lung Cellular and Molecular Physiology. 259. PMID 2260676 DOI: 10.1152/Ajplung.1990.259.6.L451  0.376
1990 Chang SW, Voelkel NF. Isolated perfused rat lung in arachidonate studies Methods in Enzymology. 187: 599-610. PMID 2233365 DOI: 10.1016/0076-6879(90)87067-D  0.395
1990 Fujimoto K, Sakai A, Yoshikawa S, Shinozaki S, Matsuzawa Y, Kubo K, Kobayashi T, Ueda G, Sekiguchi M, Voelkel NF. Effect of cyclic guanosine monophosphate on hypoxic and angiotensin-II-induced pulmonary vasoconstriction. Lung. 168: 333-343. PMID 2177815 DOI: 10.1007/Bf02719710  0.433
1990 McDonnell TJ, Westcott JY, Czartolomna J, Voelkel NF. Role of peptidoleukotrienes in hypoxic pulmonary vasoconstriction in rats American Journal of Physiology - Heart and Circulatory Physiology. 259. PMID 2118728 DOI: 10.1152/Ajpheart.1990.259.3.H751  0.431
1989 Walker BR, Haynes J, Wang HL, Voelkel NF. Vasopressin-induced pulmonary vasodilatation in rats American Journal of Physiology - Heart and Circulatory Physiology. 257. PMID 2764128 DOI: 10.1152/Ajpheart.1989.257.2.H415  0.444
1989 Sakai A, Chang SW, Voelkel NF. Importance of vasoconstriction in lipid mediator-induced pulmonary edema Journal of Applied Physiology. 66: 2667-2674. PMID 2745328 DOI: 10.1152/Jappl.1989.66.6.2667  0.479
1989 Chang SW, Voelkel NF. Charge-related lung microvascular injury American Review of Respiratory Disease. 139: 534-545. PMID 2643906 DOI: 10.1164/Ajrccm/139.2.534  0.311
1989 Chang SW, Sakai A, Voelkel NF. Dibutyryl-cAMP blocks endotoxin-induced lung injury in rats American Review of Respiratory Disease. 140: 1814-1817. PMID 2557788 DOI: 10.1164/Ajrccm/140.6.1814  0.472
1989 Wang HL, Voelkel NF. Norepinephrine induces lung vascular prostacyclin synthesis via α1-adrenergic receptors Journal of Applied Physiology. 67: 330-338. PMID 2547750  0.411
1989 Chilton FH, Westcott JY, Zapp LM, Henson JE, Voelkel NF. Incorporation of arachidonic acid into lipids of the isolated perfused rat lung Journal of Applied Physiology. 66: 2763-2771. PMID 2545663 DOI: 10.1152/Jappl.1989.66.6.2763  0.39
1989 Westcott JY, McDonnell TJ, Voelkel NF. Alveolar transfer and metabolism of eicosanoids in the rat American Review of Respiratory Disease. 139: 80-87. PMID 2536256 DOI: 10.1164/Ajrccm/139.1.80  0.391
1989 Badesch DB, Orton EC, Zapp LM, Westcott JY, Hester J, Voelkel NF, Stenmark KR. Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension American Journal of Respiratory Cell and Molecular Biology. 1: 489-498. PMID 2517777 DOI: 10.1165/Ajrcmb/1.6.489  0.527
1989 Chang SW, Stelzner TJ, Weil JV, Voelkel NF. Hypoxia increases plasma glutathione disulfide in rats Lung. 167: 269-276. PMID 2507832 DOI: 10.1007/Bf02714956  0.322
1988 Chang SW, Morris KG, McMurtry IF, Voelkel NF, Biber B. Pulmonary artery catheterization in the rat American Journal of Physiology - Heart and Circulatory Physiology. 255. PMID 3414831 DOI: 10.1152/Ajpheart.1988.255.3.H691  0.477
1988 Stenmark KR, Orton EC, Reeves JT, Voelkel NF, Crouch EC, Parks WC, Mecham RP. Vascular remodeling in neonatal pulmonary hypertension: Role of the smooth muscle cell Chest. 93: 127S-133S. PMID 3342691 DOI: 10.1378/Chest.93.3_Supplement.127S  0.477
1988 Groves BM, Turkevich D, Donnellan K, Voelkel N, Robertson AD, Reeves JT. Current approach to treatment of primary pulmonary hypertension. Chest. 93: 175S-178S. PMID 3277818 DOI: 10.1378/Chest.93.3_Supplement.175S  0.379
1988 McDonnell TJ, Chang SW, Westcott JY, Voelkel NF. Role of oxidants, eicosanoids, and neutrophils in amphotericin B lung injury in rats Journal of Applied Physiology. 65: 2195-2206. PMID 3209563 DOI: 10.1152/Jappl.1988.65.5.2195  0.372
1988 Haynes J, Chang SW, Morris KG, Voelkel NF. Platelet-activating factor antagonists increase vascular reactivity in perfused rat lungs Journal of Applied Physiology. 65: 1921-1928. PMID 3209541 DOI: 10.1152/Jappl.1988.65.5.1921  0.412
1988 Voelkel NF. Regulation mechanisms in pulmonary hypertension Praxis Und Klinik Der Pneumologie. 42: 380-382. PMID 3174595  0.486
1988 Westcott JY, McDonnell TJ, Bostwick P, Voelkel NF. Eicosanoid production in isolated perfused lungs stimulated by calcium ionophore A23187 American Review of Respiratory Disease. 138: 895-900. PMID 3144209 DOI: 10.1164/Ajrccm/138.4.895  0.357
1988 Sakai A, Voelkel NF. Dibutyryl cyclic adenosine monophosphate inhibits pulmonary vasoconstriction Lung. 166: 221-231. PMID 2905018 DOI: 10.1007/Bf02714051  0.481
1987 Worthen GS, Smedly LA, Tonnesen MG, Ellis D, Voelkel NF, Reeves JT, Henson PM. Effects of shear stress on adhesive interaction between neutrophils and cultured endothelial cells Journal of Applied Physiology. 63: 2031-2041. PMID 3693234 DOI: 10.1152/Jappl.1987.63.5.2031  0.32
1987 Weir EK, Reeves JT, McMurtry IF, Voelkel NF, Weil JV, Grover RF. Conference: Lipid Mediators in the Normal and Abnormal Pulmonary Circulation The American Review of Respiratory Disease. 136: 195-195. PMID 3605834 DOI: 10.1164/Ajrccm/136.1.195  0.447
1987 Mecham RP, Whitehouse LA, Wrenn DS, Parks WC, Griffin GL, Senior RM, Crouch EC, Stenmark KR, Voelkel NF. Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension Science. 237: 423-426. PMID 3603030 DOI: 10.1126/Science.3603030  0.493
1987 Strife RJ, Voelkel NF, Murphy RC. Mass spectrometric analysis of 5-hydroxyeicosatetraenoic acid (5-HETE) in the perfusate of the isolated rat lung American Review of Respiratory Disease. 135. PMID 3592413 DOI: 10.1164/Arrd.1987.135.6P2.S18  0.328
1987 Stenmark KR, Fasules J, Hyde DM, Voelkel NF, Henson J, Tucker A, Wilson H, Reeves JT. Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m Journal of Applied Physiology. 62: 821-830. PMID 3558241 DOI: 10.1152/Jappl.1987.62.2.821  0.528
1987 Chang SW, Feddersen CO, Henson PM, Voelkel NF. Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats Journal of Clinical Investigation. 79: 1498-1509. PMID 3553241 DOI: 10.1172/Jci112980  0.452
1987 Westcott JY, Chang S, Balazy M, Stene DO, Pradelles P, Maclouf J, Voelkel NF, Murphy RC. Analysis of 6-keto PGF1 alpha, 5-HETE, and LTC4 in rat lung: comparison of GM/MS, RIA, and EIA. Prostaglandins. 32: 857-73. PMID 3550900 DOI: 10.1016/0090-6980(86)90095-X  0.329
1987 Morganroth ML, Pickett WC, Worthen S, Mathias M, Reeves JT, Voelkel NF. Decreased Pulmonary Vascular Responsiveness In Rats Raised On An Essential Fatty Acid Deficient Diet Prostaglandins. 33: 181-197. PMID 3108962 DOI: 10.1016/0090-6980(87)90005-0  0.442
1987 Haroldsen PE, Voelkel NF, Henson JE, Henson PM, Murphy RC. Metabolism of platelet-activating factor in isolated perfused rat lung. The Journal of Clinical Investigation. 79: 1860-7. PMID 3108322 DOI: 10.1172/Jci113028  0.344
1987 Fasules JW, Stenmark KR, Henson PM, Voelkel NF, Reeves JT. Neither anticoagulant nor nonanticoagulant heparin affects monocrotaline lung injury Journal of Applied Physiology. 62: 816-820. PMID 3104299 DOI: 10.1152/Jappl.1987.62.2.816  0.574
1987 Chang SW, Westcott JY, Henson JE, Voelkel NF. Pulmonary vascular injury by polycations in perfused rat lungs Journal of Applied Physiology. 62: 1932-1943. PMID 2885303 DOI: 10.1152/Jappl.1987.62.5.1932  0.521
1986 Voelkel NF. Mechanisms of hypoxic pulmonary vasoconstriction American Review of Respiratory Disease. 133: 1186-1195. PMID 3334415 DOI: 10.1164/Arrd.1986.133.6.1186  0.478
1986 Feddersen CO, Mathias MM, McMurtry IF, Voelkel NF. Acetylcholine induces vasodilation and prostacyclin synthesis in rat lungs Prostaglandins. 31: 973-987. PMID 3088679 DOI: 10.1016/0090-6980(86)90027-4  0.471
1986 Feddersen CO, McMurtry IF, Henson P, Voelkel NF. Acetylcholine-induced pulmonary vasodilation in lung vascular injury American Review of Respiratory Disease. 133: 197-204. PMID 3004269 DOI: 10.1164/arrd.1986.133.2.197  0.402
1986 Chang SW, Voelkel NF. Actions of Opiate Agonists, Naloxone, and Paraben Preservatives in the Rat Lung Circulation Proceedings of the Society For Experimental Biology and Medicine. 181: 404-410. PMID 2868457 DOI: 10.3181/00379727-181-42272  0.493
1985 Voelkel NF, Morganroth M, Feddersen OC. Potential role of arachidonic acid metabolites in hypoxic pulmonary vasoconstriction Chest. 88. PMID 3930165 DOI: 10.1378/Chest.88.4_Supplement.245S  0.504
1985 Burghuber OC, Strife RJ, Zirrolli J, Henson PM, Henson JE, Mathias MM, Reeves JT, Murphy RC, Voelkel NF. Leukotriene inhibitors attenuate rat lung injury induced by hydrogen peroxide. The American Review of Respiratory Disease. 131: 778-85. PMID 3923881 DOI: 10.1164/Arrd.1985.131.5.778  0.353
1985 Voelkel NF. Drug effects on the pulmonary circulation: An overview Seminars in Respiratory Medicine. 7: 141-146. DOI: 10.1055/S-2007-1012651  0.506
1985 Chang S, Voelkel NF. Are there opiate receptors in the pulmonary circulation? Federation Proceedings. 44.  0.341
1984 Walker BR, Berend N, Voelkel NF. Comparison of muscular pulmonary arteries in low and high altitude hamsters and rats Respiration Physiology. 56: 45-50. PMID 6739997 DOI: 10.1016/0034-5687(84)90128-2  0.433
1984 Morganroth ML, Stenmark KR, Zirrolli JA, Mauldin R, Mathias M, Reeves JT, Murphy RC, Voelkel NF. Leukotriene C4 production during hypoxic pulmonary vasoconstriction in isolated rat lungs. Prostaglandins. 28: 867-875. PMID 6522621 DOI: 10.1016/0090-6980(84)90040-6  0.463
1984 Voelkel NF, Walker BR, Reeves JT. Chronic propranolol treatment decreases pulmonary artery pressure in conscious dogs Clinical Physiology and Biochemistry. 2: 176-183. PMID 6488695  0.356
1984 Burghuber O, Mathias MM, McMurtry IF, Reeves JT, Voelkel NF. Lung edema due to hydrogen peroxide is independent of cyclooxygenase products Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 56: 900-905. PMID 6427146 DOI: 10.1152/Jappl.1984.56.4.900  0.436
1984 Voelkel NF. Calcium-induced pulmonary vasodilation: modification by meclofenamate and ouabain Prostaglandins, Leukotrienes and Medicine. 15: 359-373. PMID 6387720 DOI: 10.1016/0262-1746(84)90135-5  0.316
1984 Grondelle Av, Worthen GS, Ellis D, Mathias MM, Murphy RC, Strife RJ, Reeves JT, Voelkel NF. Altering hydrodynamic variables influences PGI2 production by isolated lungs and endothelial cells Journal of Applied Physiology. 57: 388-395. PMID 6381438 DOI: 10.1152/Jappl.1984.57.2.388  0.365
1984 Morganroth ML, Reeves JT, Murphy RC, Voelkel NF. Leukotriene synthesis and receptor blockers block hypoxic pulmonary vasoconstriction Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 56: 1340-1346. PMID 6373695 DOI: 10.1152/Jappl.1984.56.5.1340  0.48
1984 Voelkel NF. Regulation of pulmonary vessels Praxis Und Klinik Der Pneumologie. 38: 1-7. PMID 6324159  0.439
1984 Feddersen CO, McMurtry IF, Voelkel NF. Acetylcholine (ACH) induced pulmonary vasodilation is partially inhibited by meclofenamate (MECLO) Federation Proceedings. 43.  0.353
1983 Voelkel NF, Sill V. Effect of aminophylline on hypoxic pulmonary vasoconstriction American Review of Respiratory Disease. 128: 328-329. PMID 6881692 DOI: 10.1164/Arrd.1983.128.2.328  0.534
1983 Stenmark KR, James SL, Voelkel NF. Leukotriene C4 and D4 in neonates with hypoxemia and pulmonary hypertension New England Journal of Medicine. 309: 77-80. PMID 6855869 DOI: 10.1056/Nejm198307143090204  0.54
1983 Feddersen CO, Mathias M, Murphy RC, Reeves JT, Voelkel NF. Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate Prostaglandins. 26: 869-883. PMID 6098932 DOI: 10.1016/0090-6980(83)90150-8  0.478
1982 Voelkel NF, Worthen S, Reeves JT, Henson PM, Murphy RC. Nonimmunological production of leukotrienes induced by platelet-activating factor Science. 218: 286-288. PMID 7123233 DOI: 10.1126/Science.7123233  0.367
1982 Walker BR, Voelkel NF, McMurtry IF, Adams EM. Evidence for diminished sensitivity of the hamster pulmonary vasculature to hypoxia. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 52: 1571-4. PMID 7107467 DOI: 10.1152/Jappl.1982.52.6.1571  0.377
1982 Walker BR, Voelkel NF, Reeves JT. Pulmonary pressor response after prostaglandin synthesis inhibition in conscious dogs Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 52: 705-709. PMID 7040323 DOI: 10.1152/jappl.1982.52.3.705  0.416
1982 Berend N, Christopher KL, Voelkel NF. The effect of positive end-expiratory pressure on functional residual capacity. Role of prostaglandin production American Review of Respiratory Disease. 126: 646-647. PMID 6751177 DOI: 10.1164/Arrd.1982.126.4.646  0.324
1982 Reeves JT, Voelkel NF. Arachidonate metabolism and lung-circulatory control Atemwegs- Und Lungenkrankheiten. 8: 28-35.  0.315
1981 Voelkel NF, McMurtry IF, Reeves JT. Hypoxia impairs vasodilation in the lung Journal of Clinical Investigation. 67: 238-246. PMID 7451651 DOI: 10.1172/Jci110019  0.481
1981 Niedenzu C, Grasedyck K, Voelkel NF, Bittmann S, Lindner J. Proliferation of lung cells in chronically hypoxic rats - An Autoradiographic and Radiochemical Study International Archives of Occupational and Environmental Health. 48: 185-193. PMID 7263081 DOI: 10.1007/BF00378440  0.432
1981 Voelkel NF, Newman JH, Aroyave CM, Reeves JT. Factors influencing lung histamine content Agents and Actions. 11: 204-207. PMID 7257947 DOI: 10.1007/Bf01967615  0.423
1981 Voelkel NF, Gerber JG, McMurtry IF, Nies AS, Reeves JT. Release of vasodilator prostaglandin, PGI2, from isolated rat lung during vasoconstriction Circulation Research. 48: 207-213. PMID 7006847 DOI: 10.1161/01.Res.48.2.207  0.479
1981 Voelkel NF, Hegstrand L, Reeves JT, McMurty IF, Molinoff PB. Effects of hypoxia on density of beta-adrenergic receptors. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 50: 363-6. PMID 6259101 DOI: 10.1152/Jappl.1981.50.2.363  0.315
1981 Voelkel NF, Walker BR, Reeves JT. Chronic propranolol treatment decreases hypoxic pulmonary vasoconstriction in awake dogs American Review of Respiratory Disease. 123: 241.  0.367
1980 Voelkel NF, Voelkel AI. Adrenalectomy prevents hypoxic lung histamine accumulation Agents and Actions. 10: 19-21. PMID 7386304 DOI: 10.1007/BF02024174  0.309
1980 Voelkel NF, Morris KG, McMurtry IF, Reeves JT. Calcium augments hypoxic vasoconstriction in lungs from high-altitude rats Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 49: 450-455. PMID 7204168 DOI: 10.1152/Jappl.1980.49.3.450  0.434
1980 Gerber JG, Voelkel N, Nies AS, McMurtry IF, Reeves JT. Moderation of hypoxic vasoconstriction by infused arachidonic acid: role of PGI2. Journal of Applied Physiology. 49: 107-112. PMID 6995413 DOI: 10.1152/Jappl.1980.49.1.107  0.515
1980 Voelkel NF, McMurtry IF, Reeves JT. Chronic propranolol treatment blunts right ventricular hypertrophy in rats at high altitude Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 48: 473-478. PMID 6445348 DOI: 10.1152/Jappl.1980.48.3.473  0.438
1979 Voelkel N, Voelkel A, Wiegers U, Kaukel E. A possible role of lung cAMP and cGMP for lung histamine release during chronic hypercapnia. Respiration. 38: 155-162. PMID 229534 DOI: 10.1159/000194073  0.405
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