Frank Costantini - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Genetics, Anatomy Biology, Cell Biology

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Good PI, Li L, Hurst HA, Serrano-Herrera IM, Xu K, Rao M, Bateman DA, Al-Awqati Q, D'Agati VD, Costantini F, Lin F. Low nephron endowment increases susceptibility to renal stress and chronic kidney disease. Jci Insight. PMID 36626229 DOI: 10.1172/jci.insight.161316  0.317
2021 Packard A, Klein WH, Costantini F. Ret signaling in ureteric bud epithelial cells controls cell movements, cell clustering and bud formation. Development (Cambridge, England). 148. PMID 33914865 DOI: 10.1242/dev.199386  0.397
2019 Costantini F. Generating Genetic Mosaic Mouse Embryos or Organoids for Studies of Kidney Development. Methods in Molecular Biology (Clifton, N.J.). 1926: 3-21. PMID 30742258 DOI: 10.1007/978-1-4939-9021-4_1  0.499
2016 Riccio P, Cebrian C, Zong H, Hippenmeyer S, Costantini F. Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis. Plos Biology. 14: e1002382. PMID 26894589 DOI: 10.1371/Journal.Pbio.1002382  0.817
2016 Leclerc K, Costantini F. Mosaic analysis of cell rearrangements during ureteric bud branching in dissociated/reaggregated kidney cultures and in vivo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 245: 483-96. PMID 26813041 DOI: 10.1002/dvdy.24387  0.444
2015 Akagi T, Kuure S, Uranishi K, Koide H, Costantini F, Yokota T. ETS-related transcription factors ETV4 and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells. The Journal of Biological Chemistry. 290: 22460-73. PMID 26224636 DOI: 10.1074/Jbc.M115.675595  0.434
2014 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A. Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development (Cambridge, England). 141: 3420-30. PMID 25139858 DOI: 10.1242/Dev.113928  0.441
2014 Yun K, Ajima R, Sharma N, Costantini F, Mackem S, Lewandoski M, Yamaguchi TP, Perantoni AO. Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension. Human Molecular Genetics. 23: 6807-14. PMID 25082826 DOI: 10.1093/Hmg/Ddu397  0.52
2014 Cebrian C, Asai N, D'Agati V, Costantini F. The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment. Cell Reports. 7: 127-37. PMID 24656820 DOI: 10.1016/j.celrep.2014.02.033  0.394
2014 Ihermann-Hella A, Lume M, Miinalainen IJ, Pirttiniemi A, Gui Y, Peränen J, Charron J, Saarma M, Costantini F, Kuure S. Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion. Plos Genetics. 10: e1004193. PMID 24603431 DOI: 10.1371/journal.pgen.1004193  0.387
2014 Cullen-McEwen LA, Young RJ, Fricout G, Jeulin D, Harper IS, Costantini F, Bertram JF. Imaging tools for analysis of the ureteric tree in the developing mouse kidney. Methods in Molecular Biology (Clifton, N.J.). 1075: 305-20. PMID 24052360 DOI: 10.1007/978-1-60761-847-8_16  0.358
2013 Packard A, Georgas K, Michos O, Riccio P, Cebrian C, Combes AN, Ju A, Ferrer-Vaquer A, Hadjantonakis AK, Zong H, Little MH, Costantini F. Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud. Developmental Cell. 27: 319-30. PMID 24183650 DOI: 10.1016/J.Devcel.2013.09.001  0.802
2012 Costantini F. Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 693-713. PMID 22942910 DOI: 10.1002/wdev.52  0.369
2011 Kitagaki J, Ueda Y, Chi X, Sharma N, Elder CM, Truffer E, Costantini F, Lewandoski M, Perantoni AO. FGF8 is essential for formation of the ductal system in the male reproductive tract. Development (Cambridge, England). 138: 5369-78. PMID 22110055 DOI: 10.1242/Dev.051888  0.445
2011 Willecke R, Heuberger J, Grossmann K, Michos O, Schmidt-Ott K, Walentin K, Costantini F, Birchmeier W. The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney. Developmental Biology. 360: 310-7. PMID 22015719 DOI: 10.1016/J.Ydbio.2011.09.029  0.504
2011 Costantini F, Watanabe T, Lu B, Chi X, Srinivas S. Imaging kidney development. Cold Spring Harbor Protocols. 2011: pdb.top109. PMID 21536773 DOI: 10.1101/Pdb.Top109  0.812
2011 Costantini F, Watanabe T, Lu B, Chi X, Srinivas S. Dissection of embryonic mouse kidney, culture in vitro, and imaging of the developing organ. Cold Spring Harbor Protocols. 2011: pdb.prot5613. PMID 21536763 DOI: 10.1101/Pdb.Prot5613  0.778
2011 Reginensi A, Clarkson M, Neirijnck Y, Lu B, Ohyama T, Groves AK, Sock E, Wegner M, Costantini F, Chaboissier MC, Schedl A. SOX9 controls epithelial branching by activating RET effector genes during kidney development. Human Molecular Genetics. 20: 1143-53. PMID 21212101 DOI: 10.1093/Hmg/Ddq558  0.722
2011 Kim H, Won S, Hwang DY, Lee JS, Kim M, Kim R, Kim W, Cha B, Kim T, Kim D, Costantini F, Jho EH. Downregulation of Wnt/β-catenin signaling causes degeneration of hippocampal neurons in vivo. Neurobiology of Aging. 32: 2316.e1-15. PMID 20409609 DOI: 10.1016/J.Neurobiolaging.2010.03.013  0.351
2011 Thowfeequ S, Kuure S, Lu B, Potter S, Costantini F. Identification and characterization of Etv4/5 target genes during ureteric bud branching morphogenesis Developmental Biology. 356: 167-168. DOI: 10.1016/J.Ydbio.2011.05.621  0.591
2011 Riccio PN, Enomoto H, Costantini F. The fate of Ret-expressing cells in the kidney and their role in maintaining renal branching morphogenesis Developmental Biology. 356: 167. DOI: 10.1016/J.Ydbio.2011.05.620  0.808
2011 Burn SF, Brunskill EW, Potter SS, Lu BC, Wu Z, Costantini F. Identifying genes involved in ureteric bud morphogenesis Developmental Biology. 356: 142. DOI: 10.1016/J.Ydbio.2011.05.142  0.601
2010 Costantini F. GDNF/Ret signaling and renal branching morphogenesis: From mesenchymal signals to epithelial cell behaviors. Organogenesis. 6: 252-62. PMID 21220964 DOI: 10.4161/Org.6.4.12680  0.583
2010 Kuure S, Cebrian C, Machingo Q, Lu BC, Chi X, Hyink D, D'Agati V, Gurniak C, Witke W, Costantini F. Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis. Plos Genetics. 6: e1001176. PMID 21060807 DOI: 10.1371/Journal.Pgen.1001176  0.719
2010 Krawchuk D, Weiner SJ, Chen YT, Lu BC, Costantini F, Behringer RR, Laufer E. Twist1 activity thresholds define multiple functions in limb development. Developmental Biology. 347: 133-46. PMID 20732316 DOI: 10.1016/J.Ydbio.2010.08.015  0.64
2010 Costantini F, Kopan R. Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Developmental Cell. 18: 698-712. PMID 20493806 DOI: 10.1016/J.Devcel.2010.04.008  0.456
2010 Kuure S, Chi X, Lu B, Costantini F. The transcription factors Etv4 and Etv5 mediate formation of the ureteric bud tip domain during kidney development. Development (Cambridge, England). 137: 1975-9. PMID 20463033 DOI: 10.1242/Dev.051656  0.733
2010 Michos O, Cebrian C, Hyink D, Grieshammer U, Williams L, D'Agati V, Licht JD, Martin GR, Costantini F. Kidney development in the absence of Gdnf and Spry1 requires Fgf10. Plos Genetics. 6: e1000809. PMID 20084103 DOI: 10.1371/Journal.Pgen.1000809  0.54
2010 Rosselot C, Spraggon L, Chia I, Batourina E, Riccio P, Lu B, Niederreither K, Dolle P, Duester G, Chambon P, Costantini F, Gilbert T, Molotkov A, Mendelsohn C. Non-cell-autonomous retinoid signaling is crucial for renal development. Development (Cambridge, England). 137: 283-92. PMID 20040494 DOI: 10.1242/Dev.040287  0.798
2010 Lu BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, ... ... Costantini F, et al. Erratum: Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis Nature Genetics. 42: 361-361. DOI: 10.1038/Ng0410-361D  0.682
2010 Costantini F, Burn S, Cebrian C, Chi X, Kuure S, Lu B, Michos O, Riccio P, Williams L, Wu Z. O28. Control of branching morphogenesis during kidney development Differentiation. 80: S14. DOI: 10.1016/J.Diff.2010.09.171  0.811
2010 Kuure S, Cebrian C, Quentin M, Lu B, Chi X, Deborah H, D’Agati V, Gurniak C, Walter W, Costantini F. P87. Actin depolymerizing factors Cfl1 and Dstn are required for ureteric bud branching morphogenesis Differentiation. 80. DOI: 10.1016/J.Diff.2010.09.093  0.716
2009 Lu BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, ... ... Costantini F, et al. Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis. Nature Genetics. 41: 1295-302. PMID 19898483 DOI: 10.1038/Ng.476  0.727
2009 Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M, Mendelsohn C, Costantini F. Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Developmental Cell. 17: 199-209. PMID 19686681 DOI: 10.1016/J.Devcel.2009.07.013  0.81
2009 Chia IV, Kim MJ, Itoh K, Sokol SY, Costantini F. Both the RGS domain and the six C-terminal amino acids of mouse Axin are required for normal embryogenesis. Genetics. 181: 1359-68. PMID 19204372 DOI: 10.1534/Genetics.109.101055  0.358
2009 Chi X, Hadjantonakis AK, Wu Z, Hyink D, Costantini F. A transgenic mouse that reveals cell shape and arrangement during ureteric bud branching. Genesis (New York, N.Y. : 2000). 47: 61-6. PMID 19111008 DOI: 10.1002/Dvg.20452  0.509
2009 Michos O, Hyink D, Uta G, Jonathan L, Martin G, Costantini F. 13-P066 SPROUTY1 and RTK signaling in kidney development Mechanisms of Development. 126: S214. DOI: 10.1016/J.Mod.2009.06.539  0.396
2009 Costantini F. S08-02 Control of branching morphogenesis during kidney development Mechanisms of Development. 126: S32. DOI: 10.1016/J.Mod.2009.06.1040  0.378
2008 Grote D, Boualia SK, Souabni A, Merkel C, Chi X, Costantini F, Carroll T, Bouchard M. Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction. Plos Genetics. 4: e1000316. PMID 19112489 DOI: 10.1371/Journal.Pgen.1000316  0.516
2008 Chiu SY, Asai N, Costantini F, Hsu W. SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. Plos Biology. 6: e310. PMID 19090619 DOI: 10.1371/Journal.Pbio.0060310  0.419
2008 Kitamura T, Asai N, Enomoto A, Maeda K, Kato T, Ishida M, Jiang P, Watanabe T, Usukura J, Kondo T, Costantini F, Murohara T, Takahashi M. Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nature Cell Biology. 10: 329-37. PMID 18264090 DOI: 10.1038/Ncb1695  0.545
2008 Grote D, Souabni A, Chi X, Merkel CE, Carroll TJ, Costantini F, Bouchard M. Gata3 and its role in urogenital system development Developmental Biology. 319: 605. DOI: 10.1016/J.Ydbio.2008.05.448  0.308
2007 Mijatovic J, Airavaara M, Planken A, Auvinen P, Raasmaja A, Piepponen TP, Costantini F, Ahtee L, Saarma M. Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4799-809. PMID 17475787 DOI: 10.1523/Jneurosci.5647-06.2007  0.302
2007 Cañibano C, Rodriguez NL, Saez C, Tovar S, Garcia-Lavandeira M, Borrello MG, Vidal A, Costantini F, Japon M, Dieguez C, Alvarez CV. The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth. The Embo Journal. 26: 2015-28. PMID 17380130 DOI: 10.1038/Sj.Emboj.7601636  0.362
2007 Yu HM, Liu B, Costantini F, Hsu W. Impaired neural development caused by inducible expression of Axin in transgenic mice. Mechanisms of Development. 124: 146-56. PMID 17123792 DOI: 10.1016/J.Mod.2006.10.002  0.454
2007 Costantini F. GDNF/Ret signaling and renal branching morphogenesis Developmental Biology. 306: 304. DOI: 10.1016/J.Ydbio.2007.03.091  0.459
2006 Asai N, Fukuda T, Wu Z, Enomoto A, Pachnis V, Takahashi M, Costantini F. Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells. Development (Cambridge, England). 133: 4507-16. PMID 17050626 DOI: 10.1242/Dev.02616  0.396
2006 Basson MA, Watson-Johnson J, Shakya R, Akbulut S, Hyink D, Costantini FD, Wilson PD, Mason IJ, Licht JD. Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1. Developmental Biology. 299: 466-77. PMID 17022962 DOI: 10.1016/J.Ydbio.2006.08.051  0.7
2006 Costantini F. Renal branching morphogenesis: concepts, questions, and recent advances. Differentiation; Research in Biological Diversity. 74: 402-21. PMID 16916378 DOI: 10.1111/J.1432-0436.2006.00106.X  0.448
2006 Costantini F, Shakya R. GDNF/Ret signaling and the development of the kidney. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 28: 117-27. PMID 16435290 DOI: 10.1002/Bies.20357  0.722
2005 Wong A, Bogni S, Kotka P, de Graaff E, D'Agati V, Costantini F, Pachnis V. Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. Molecular and Cellular Biology. 25: 9661-73. PMID 16227613 DOI: 10.1128/Mcb.25.21.9661-9673.2005  0.467
2005 Yu HM, Liu B, Chiu SY, Costantini F, Hsu W. Development of a unique system for spatiotemporal and lineage-specific gene expression in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 8615-20. PMID 15941831 DOI: 10.1073/Pnas.0500124102  0.41
2005 Schmidt-Ott KM, Yang J, Chen X, Wang H, Paragas N, Mori K, Li JY, Lu B, Costantini F, Schiffer M, Bottinger E, Barasch J. Novel regulators of kidney development from the tips of the ureteric bud. Journal of the American Society of Nephrology : Jasn. 16: 1993-2002. PMID 15917337 DOI: 10.1681/Asn.2004121127  0.692
2005 Chia IV, Costantini F. Mouse axin and axin2/conductin proteins are functionally equivalent in vivo. Molecular and Cellular Biology. 25: 4371-6. PMID 15899843 DOI: 10.1128/Mcb.25.11.4371-4376.2005  0.447
2005 Shakya R, Jho EH, Kotka P, Wu Z, Kholodilov N, Burke R, D'Agati V, Costantini F. The role of GDNF in patterning the excretory system. Developmental Biology. 283: 70-84. PMID 15890330 DOI: 10.1016/J.Ydbio.2005.04.008  0.703
2005 Yu HM, Jerchow B, Sheu TJ, Liu B, Costantini F, Puzas JE, Birchmeier W, Hsu W. The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development (Cambridge, England). 132: 1995-2005. PMID 15790973 DOI: 10.1242/Dev.01786  0.441
2005 Tamamura Y, Otani T, Kanatani N, Koyama E, Kitagaki J, Komori T, Yamada Y, Costantini F, Wakisaka S, Pacifici M, Iwamoto M, Enomoto-Iwamoto M. Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification. The Journal of Biological Chemistry. 280: 19185-95. PMID 15760903 DOI: 10.1074/Jbc.M414275200  0.375
2005 Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Developmental Cell. 8: 229-39. PMID 15691764 DOI: 10.1016/J.Devcel.2004.12.004  0.669
2005 Shakya R, Watanabe T, Costantini F. The role of GDNF/Ret signaling in ureteric bud cell fate and branching morphogenesis. Developmental Cell. 8: 65-74. PMID 15621530 DOI: 10.1016/J.Devcel.2004.11.008  0.754
2005 Belteki G, Haigh J, Kabacs N, Haigh K, Sison K, Costantini F, Whitsett J, Quaggin SE, Nagy A. Erratum: Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction (Nucleic Acids Research (2005) vol. 33 (e51)) Nucleic Acids Research. 33. DOI: 10.1093/Nar/Gki559  0.301
2004 Choi J, Park SY, Costantini F, Jho EH, Joo CK. Adenomatous polyposis coli is down-regulated by the ubiquitin-proteasome pathway in a process facilitated by Axin. The Journal of Biological Chemistry. 279: 49188-98. PMID 15355978 DOI: 10.1074/Jbc.M404655200  0.355
2004 Watanabe T, Costantini F. Real-time analysis of ureteric bud branching morphogenesis in vitro. Developmental Biology. 271: 98-108. PMID 15196953 DOI: 10.1016/J.Ydbio.2004.03.025  0.626
2002 Batourina E, Choi C, Paragas N, Bello N, Hensle T, Costantini FD, Schuchardt A, Bacallao RL, Mendelsohn CL. Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret. Nature Genetics. 32: 109-15. PMID 12195422 DOI: 10.1038/Ng952  0.349
2002 Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Molecular and Cellular Biology. 22: 1172-83. PMID 11809808 DOI: 10.1128/Mcb.22.4.1172-1183.2002  0.384
2001 Hsu W, Shakya R, Costantini F. Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. The Journal of Cell Biology. 155: 1055-64. PMID 11739413 DOI: 10.1083/Jcb.200107066  0.662
2001 de Graaff E, Srinivas S, Kilkenny C, D'Agati V, Mankoo BS, Costantini F, Pachnis V. Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes & Development. 15: 2433-44. PMID 11562352 DOI: 10.1101/Gad.205001  0.485
2001 Yu X, Lin CS, Costantini F, Noguchi CT. The human erythropoietin receptor gene rescues erythropoiesis and developmental defects in the erythropoietin receptor null mouse. Blood. 98: 475-7. PMID 11435319 DOI: 10.1182/Blood.V98.2.475  0.331
2001 Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, Jessell TM, Costantini F. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. Bmc Developmental Biology. 1: 4. PMID 11299042 DOI: 10.1186/1471-213X-1-4  0.572
2001 Ruvinsky A, Flood W, Costantini F. Developmental mosaicism may explain spontaneous reappearance of the Axin(Fu) mutation in mice. Genesis (New York, N.Y. : 2000). 29: 49-54. PMID 11170344 DOI: 10.1002/1526-968X(200102)29:2<49::Aid-Gene1004>3.0.Co;2-2  0.304
2001 Fabry ME, Suzuka SM, Weinberg RS, Lawrence C, Factor SM, Gilman JG, Costantini F, Nagel RL. Second generation knockout sickle mice: the effect of HbF. Blood. 97: 410-8. PMID 11154217 DOI: 10.1182/Blood.V97.2.410  0.363
2001 Batourina E, Gim S, Bello N, Shy M, Clagett-Dame M, Srinivas S, Costantini F, Mendelsohn C. Vitamin A controls epithelial/mesenchymal interactions through Ret expression Nature Genetics. 27: 74-78. PMID 11138002 DOI: 10.1038/83792  0.549
2001 Ruvinsky A, Flood WD, Zhang T, Costantini F. Unusual inheritance of the AxinFu mutation in mice is associated with widespread rearrangements in the proximal region of chromosome 17. Genetical Research. 76: 135-47. PMID 11132407 DOI: 10.1017/S0016672300004651  0.305
2000 Primot A, Baratte B, Gompel M, Borgne A, Liabeuf S, Romette JL, Jho EH, Costantini F, Meijer L. Purification of GSK-3 by affinity chromatography on immobilized axin. Protein Expression and Purification. 20: 394-404. PMID 11087679 DOI: 10.1006/Prep.2000.1321  0.305
2000 Bauchwitz R, Costantini F. Developmentally distinct effects on human ε-, γ- and δ-globin levels caused by the absence or altered position of the human β-globin gene in YAC transgenic mice Human Molecular Genetics. 9: 561-574. PMID 10699179 DOI: 10.1093/Hmg/9.4.561  0.329
2000 Smith-Hicks CL, Sizer KC, Powers JF, Tischler AS, Costantini F. C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B. The Embo Journal. 19: 612-22. PMID 10675330 DOI: 10.1093/Emboj/19.4.612  0.422
1999 Jho Eh, Lomvardas S, Costantini F. A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression. Biochemical and Biophysical Research Communications. 266: 28-35. PMID 10581160 DOI: 10.1006/Bbrc.1999.1760  0.304
1999 Fagotto F, Jho Eh, Zeng L, Kurth T, Joos T, Kaufmann C, Costantini F. Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization. The Journal of Cell Biology. 145: 741-56. PMID 10330403 DOI: 10.1083/Jcb.145.4.741  0.326
1999 Srinivas S, Goldberg MR, Watanabe T, D'Agati V, al-Awqati Q, Costantini F. Expression of green fluorescent protein in the ureteric bud of transgenic mice: a new tool for the analysis of ureteric bud morphogenesis. Developmental Genetics. 24: 241-51. PMID 10322632 DOI: 10.1002/(Sici)1520-6408(1999)24:3/4<241::Aid-Dvg7>3.0.Co;2-R  0.644
1998 Lim S, Kim H, Lim SK, Ali Ab, Lim YK, Wang Y, Chong SM, Costantini F, Baumman H. Increased susceptibility in Hp knockout mice during acute hemolysis. Blood. 92: 1870-1877. DOI: 10.1182/Blood.V92.6.1870.418K38_1870_1877  0.323
1997 Lim SK, Bieker JJ, Lin CS, Costantini F. A shortened life span of EKLF-/- adult erythrocytes, due to a deficiency of β-globin chains, is ameliorated by human γ-globin chains Blood. 90: 1291-1299. PMID 9242564 DOI: 10.1182/Blood.V90.3.1291.1291_1291_1299  0.371
1997 Zeng L, Fagotto F, Zhang T, Hsu W, Vasicek TJ, Perry WL, Lee JJ, Tilghman SM, Gumbiner BM, Costantini F. The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell. 90: 181-92. PMID 9230313 DOI: 10.1016/S0092-8674(00)80324-4  0.399
1997 Romero JR, Fabry ME, Suzuka SM, Costantini F, Nagel RL, Canessa M. K:Cl cotransport in red cells of transgenic mice expressing high levels of human hemoglobin S. American Journal of Hematology. 55: 112-4. PMID 9209008 DOI: 10.1002/(Sici)1096-8652(199706)55:2<112::Aid-Ajh11>3.0.Co;2-G  0.349
1996 Fabry ME, Kennan RP, Pàszty C, Costantini F, Rubin EM, Gore JC, Nagel RL. Magnetic Resonance Evidence of Hypoxia in a Homozygous Alpha-Knockout of a Transgenic Mouse Model for Sickle Cell Disease Journal of Clinical Investigation. 98: 2450-2455. PMID 8958206 DOI: 10.1172/Jci119062  0.347
1996 Rothman TP, Chen J, Howard MJ, Costantini F, Schuchardt A, Pachnis V, Gershon MD. Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice. Developmental Biology. 178: 498-513. PMID 8812145 DOI: 10.1006/Dbio.1996.0234  0.349
1996 Kaul DK, Fabry ME, Costantini F, Rubin EM, Nagel RL. In vivo demonstration of red cell-endothelial interaction, sickling and altered microvascular response to oxygen in the sickle transgenic mouse. The Journal of Clinical Investigation. 96: 2845-53. PMID 8675655 DOI: 10.1172/Jci118355  0.403
1996 Durbec P, Marcos-Gutierrez CV, Kilkenny C, Grigoriou M, Wartiowaara K, Suvanto P, Smith D, Ponder B, Costantini F, Saarma M, Sariola H, Pachnis V. GDNF signalling through the Ret receptor tyrosine kinase Nature. 381: 789-793. PMID 8657282 DOI: 10.1038/381789A0  0.45
1996 Lin CS, Lim SK, D'Agati V, Costantini F. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes & Development. 10: 154-64. PMID 8566749 DOI: 10.1101/Gad.10.2.154  0.499
1995 Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. RET-deficient mice: an animal model for Hirschsprung's disease and renal agenesis. Journal of Internal Medicine. 238: 327-32. PMID 7595168 DOI: 10.1111/J.1365-2796.1995.Tb01206.X  0.386
1994 Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature. 367: 380-3. PMID 8114940 DOI: 10.1038/367380A0  0.493
1994 Enver T, Li Q, Gale KB, Hu M, May GE, Karlinsey JE, Jimenez G, Papayannopoulou T, Costantini F. Analysis of the developmental and transcriptional potentiation functions of 5'HS2 of the murine beta-globin locus control region in transgenic mice. Developmental Biology. 165: 574-84. PMID 7958423 DOI: 10.1006/Dbio.1994.1277  0.379
1993 Cheng SS, Costantini F. Morula decompaction (mdn), a preimplantation recessive lethal defect in a transgenic mouse line. Developmental Biology. 156: 265-77. PMID 8449371 DOI: 10.1006/Dbio.1993.1075  0.375
1993 Himelstein A, Ward M, Podda S, De la Flor Weiss E, Costantini F, Bank A. Long-term high-level expression of human β-globin occurs following transplantation of transgenic marrow into irradiated mice American Journal of Hematology. 42: 254-261. PMID 8438898 DOI: 10.1002/Ajh.2830420304  0.339
1993 Simon MC, Pevny L, Wiles MV, Keller G, Costantini F, Orkin SH. Rescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cells. Nature Genetics. 1: 92-8. PMID 1302015 DOI: 10.1038/Ng0592-92  0.439
1991 Son HJ, Shahan K, Rodriguez M, Derman E, Costantini F. Identification of an enhancer required for the expression of a mouse major urinary protein gene in the submaxillary gland. Molecular and Cellular Biology. 11: 4244-52. PMID 2072918 DOI: 10.1128/Mcb.11.8.4244  0.333
1991 Pevny L, Simon MC, Robertson E, Klein WH, Tsai SF, D'Agati V, Orkin SH, Costantini F. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature. 349: 257-60. PMID 1987478 DOI: 10.1038/349257A0  0.449
1991 Trudel M, D'Agati V, Costantini F. C-myc as an inducer of polycystic kidney disease in transgenic mice Kidney International. 39: 665-671. PMID 1646908 DOI: 10.1038/Ki.1991.80  0.463
1990 Enver T, Raich N, Ebens AJ, Papayannopoulou T, Costantini F, Stamatoyannopoulos G. Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice. Nature. 344: 309-13. PMID 2314472 DOI: 10.1038/344309A0  0.344
1990 Perez-Stable C, Costantini F. Roles of fetal G gamma-globin promoter elements and the adult beta-globin 3' enhancer in the stage-specific expression of globin genes. Molecular and Cellular Biology. 10: 1116-25. PMID 2304460 DOI: 10.1128/Mcb.10.3.1116  0.337
1990 Pachnis V, Pevny L, Rothstein R, Costantini F. Transfer of a yeast artificial chromosome carrying human DNA from Saccharomyces cerevisiae into mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 5109-13. PMID 2195548 DOI: 10.1073/Pnas.87.13.5109  0.307
1990 Ren RB, Costantini F, Gorgacz EJ, Lee JJ, Racaniello VR. Transgenic mice expressing a human poliovirus receptor: a new model for poliomyelitis. Cell. 63: 353-62. PMID 2170026 DOI: 10.1016/0092-8674(90)90168-E  0.334
1989 Shi Y, Son HJ, Shahan K, Rodriguez M, Costantini F, Derman E. Silent genes in the mouse major urinary protein gene family. Proceedings of the National Academy of Sciences of the United States of America. 86: 4584-8. PMID 2734309 DOI: 10.1073/Pnas.86.12.4584  0.342
1989 Magram J, Niederreither K, Costantini F. Beta-globin enhancers target expression of a heterologous gene to erythroid tissues of transgenic mice. Molecular and Cellular Biology. 9: 4581-4. PMID 2555696 DOI: 10.1128/Mcb.9.10.4581  0.346
1987 Trudel M, Magram J, Bruckner L, Costantini F. Upstream G gamma-globin and downstream beta-globin sequences required for stage-specific expression in transgenic mice Molecular and Cellular Biology. 7: 4024-4029. PMID 2828925 DOI: 10.1128/Mcb.7.11.4024  0.339
1987 Soares Vda C, Gubits RM, Feigelson P, Costantini F. Tissue-specific and hormonally regulated expression of a rat alpha 2u globulin gene in transgenic mice. Molecular and Cellular Biology. 7: 3749-58. PMID 2446121 DOI: 10.1128/Mcb.7.10.3749  0.338
1986 Chada K, Magram J, Costantini F. An embryonic pattern of expression of a human fetal globin gene in transgenic mice. Nature. 319: 685-9. PMID 3951540 DOI: 10.1038/319685A0  0.374
1986 Radice G, Costantini F. Tissue-specific DNase I hypersensitive sites in a foreign globin gene in transgenic mice Nucleic Acids Research. 14: 9765-9780. PMID 3808955 DOI: 10.1093/Nar/14.24.9765  0.391
1985 Chada K, Magram J, Raphael K, Radice G, Lacy E, Costantini F. Specific expression of a foreign beta-globin gene in erythroid cells of transgenic mice. Nature. 314: 377-80. PMID 3982505 DOI: 10.1038/314377A0  0.39
1985 Costantini F, Radice G, Magram J, Stamatoyannopoulos G, Papayannopoulou T, Chada K. Developmental regulation of human globin genes in transgenic mice. Cold Spring Harbor Symposia On Quantitative Biology. 50: 361-70. PMID 3868484 DOI: 10.1101/Sqb.1985.050.01.046  0.367
1985 Magram J, Chada K, Costantini F. Developmental regulation of a cloned adult beta-globin gene in transgenic mice. Nature. 315: 338-40. PMID 3858676 DOI: 10.1038/315338A0  0.398
1984 Grosschedl R, Weaver D, Baltimore D, Costantini F. Introduction of a mu immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody. Cell. 38: 647-58. PMID 6091894 DOI: 10.1016/0092-8674(84)90259-9  0.375
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