Philippe M. Frossard, PhD - Publications

Affiliations: 
Biological and Biomedical Sciences The Aga Khan University 
Area:
Genetics Stroke

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Harshfield EL, Koulman A, Ziemek D, Marney L, Fauman EB, Paul DS, Stacey D, Rasheed A, Lee JJ, Shah N, Jabeen S, Imran A, Abbas S, Hina Z, Qamar N, ... ... Frossard P, et al. An unbiased lipid phenotyping approach to study the genetic determinants of lipids and their association with coronary heart disease risk factors. Journal of Proteome Research. PMID 30887811 DOI: 10.1021/Acs.Jproteome.8B00786  0.305
2017 Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, ... ... Frossard P, et al. Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics. PMID 29083408 DOI: 10.1038/Ng.3977  0.315
2017 Zhao W, Rasheed A, Tikkanen E, Lee JJ, Butterworth AS, Howson JMM, Assimes TL, Chowdhury R, Orho-Melander M, Damrauer S, Small A, Asma S, Imamura M, Yamauch T, Chambers JC, ... ... Frossard P, et al. Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. Nature Genetics. PMID 28869590 DOI: 10.1038/Ng.3943  0.347
2017 Howson JMM, Zhao W, Barnes DR, Ho WK, Young R, Paul DS, Waite LL, Freitag DF, Fauman EB, Salfati EL, Sun BB, Eicher JD, Johnson AD, Sheu WHH, Nielsen SF, ... ... Frossard P, et al. Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. Nature Genetics. PMID 28530674 DOI: 10.1038/Ng.3874  0.366
2017 Saleheen D, Zhao W, Young R, Nelson CP, Ho WK, Ferguson JF, Rasheed A, Ou K, Nurnberg ST, Bauer RC, Goel A, Do R, Stewart AFR, Hartiala J, Zhang W, ... ... Frossard PM, et al. Loss of Cardio-Protective Effects at the ADAMTS7 Locus Due to Gene-Smoking Interactions. Circulation. PMID 28461624 DOI: 10.1161/Circulationaha.116.022069  0.339
2017 Saleheen D, Natarajan P, Armean IM, Zhao W, Rasheed A, Khetarpal SA, Won HH, Karczewski KJ, O'Donnell-Luria AH, Samocha KE, Weisburd B, Gupta N, Zaidi M, Samuel M, Imran A, ... ... Frossard P, et al. Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity. Nature. 544: 235-239. PMID 28406212 DOI: 10.1038/Nature22034  0.381
2017 Stitziel NO, Khera AV, Wang X, Bierhals AJ, Vourakis AC, Sperry AE, Natarajan P, Klarin D, Emdin CA, Zekavat SM, Nomura A, Erdmann J, Schunkert H, Samani NJ, Kraus WE, ... ... Frossard PM, et al. ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. Journal of the American College of Cardiology. PMID 28385496 DOI: 10.1016/J.Jacc.2017.02.030  0.31
2016 Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, ... ... Frossard P, et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics. PMID 27618447 DOI: 10.1038/Ng.3654  0.364
2016 Imamura M, Takahashi A, Yamauchi T, Hara K, Yasuda K, Grarup N, Zhao W, Wang X, Huerta-Chagoya A, Hu C, Moon S, Long J, Kwak SH, Rasheed A, Saxena R, ... ... Frossard P, et al. Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. Nature Communications. 7: 10531. PMID 26818947 DOI: 10.1038/Ncomms10531  0.323
2015 Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T, Nelson CP, Hopewell JC, Webb TR, Zeng L, Dehghan A, Alver M, Armasu SM, ... ... Frossard P, et al. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature Genetics. 47: 1121-30. PMID 26343387 DOI: 10.1038/Ng.3396  0.369
2014 Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Frossard P, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897  0.359
2013 Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho WK, Rasheed A, Frossard P, Sim X, Hassanali N, Radha V, Chidambaram M, Liju S, et al. Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. Diabetes. 62: 1746-55. PMID 23300278 DOI: 10.2337/Db12-1077  0.333
2012 Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, Rasheed A, Zeginigg M, Attia J, Baker R, Barlera S, Biffi A, Bookman E, Brott TG, Brown RD, ... ... Frossard P, et al. Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke; a Journal of Cerebral Circulation. 43: 980-6. PMID 22363065 DOI: 10.1161/Strokeaha.111.632075  0.341
2011 Kooner JS, Saleheen D, Sim X, Sehmi J, Zhang W, Frossard P, Been LF, Chia KS, Dimas AS, Hassanali N, Jafar T, Jowett JB, Li X, Radha V, Rees SD, et al. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nature Genetics. 43: 984-9. PMID 21874001 DOI: 10.1038/Ng.921  0.343
2011 Butterworth AS, Braund PS, Farrall M, Hardwick RJ, Saleheen D, Peden JF, Soranzo N, Chambers JC, Sivapalaratnam S, Kleber ME, Keating B, Qasim A, Klopp N, Erdmann J, Assimes TL, ... ... Frossard P, et al. Large-scale gene-centric analysis identifies novel variants for coronary artery disease Plos Genetics. 7. DOI: 10.1371/Journal.Pgen.1002260  0.429
2010 Saleheen D, Soranzo N, Rasheed A, Scharnagl H, Gwilliam R, Alexander M, Inouye M, Zaidi M, Potter S, Haycock P, Bumpstead S, Kaptoge S, Di Angelantonio E, Sarwar N, Hunt SE, ... ... Frossard P, et al. Genetic determinants of major blood lipids in Pakistanis compared with Europeans. Circulation. Cardiovascular Genetics. 3: 348-57. PMID 20570915 DOI: 10.1161/Circgenetics.109.906180  0.369
2009 Saleheen D, Zaidi M, Rasheed A, Ahmad U, Hakeem A, Murtaza M, Kayani W, Faruqui A, Kundi A, Zaman KS, Yaqoob Z, Cheema LA, Samad A, Rasheed SZ, Mallick NH, ... ... Frossard P, et al. The Pakistan Risk of Myocardial Infarction Study: a resource for the study of genetic, lifestyle and other determinants of myocardial infarction in South Asia. European Journal of Epidemiology. 24: 329-38. PMID 19404752 DOI: 10.1007/S10654-009-9334-Y  0.339
2008 Khawaja MR, Taj F, Saleheen D, Ahmad U, Chohan MO, Jafar T, Frossard PM. Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population. Journal of Human Hypertension. 22: 60-2. PMID 17611547 DOI: 10.1038/Sj.Jhh.1002257  0.39
2007 Saleheen D, Ali T, Aly Z, Khealani B, Frossard PM. Novel mutation in the PANK2 gene leads to pantothenate kinase-associated neurodegeneration in a Pakistani family. Pediatric Neurology. 37: 296-8. PMID 17903678 DOI: 10.1016/J.Pediatrneurol.2007.05.015  0.342
2007 Saeed M, Perwaiz Iqbal M, Yousuf FA, Perveen S, Shafiq M, Sajid J, Frossard PM. Interactions and associations of paraoxonase gene cluster polymorphisms with myocardial infarction in a Pakistani population. Clinical Genetics. 71: 238-44. PMID 17309646 DOI: 10.1111/J.1399-0004.2007.00753.X  0.392
2007 Saleheen D, Khanum S, Haider SR, Nazir A, Ahmad U, Khalid H, Hussain I, Shuja F, Shahid K, Habib A, Frossard PM. A novel haplotype in ABCA1 gene effects plasma HDL-C concentration. International Journal of Cardiology. 115: 7-13. PMID 16806540 DOI: 10.1016/J.Ijcard.2005.12.020  0.345
2007 Khawaja MR, Taj F, Ahmad U, Saleheen D, Jafar T, Frossard PM. Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population. International Journal of Cardiology. 116: 113-5. PMID 16765468 DOI: 10.1016/J.Ijcard.2006.04.019  0.358
2006 Saleheen D, Merwat SN, Frossard P. Haplotype association of the adrenergic β2 receptor gene with essential hypertension [2] Journal of Human Hypertension. 20: 167-168. PMID 16252000 DOI: 10.1038/Sj.Jhh.1001949  0.37
2006 Saleheen D, Nazir A, Khanum S, Haider SR, Frossard PM. R1615P: a novel mutation in ABCA1 associated with low levels of HDL and type II diabetes mellitus. International Journal of Cardiology. 110: 259-60. PMID 16055210 DOI: 10.1016/J.Ijcard.2005.06.059  0.328
2005 Iqbal MP, Fatima T, Parveen S, Yousuf FA, Shafiq M, Mehboobali N, Khan AH, Azam I, Frossard PM. Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 1: 26-32. PMID 19565010 DOI: 10.4172/1747-0862.1000007  0.35
2005 Saleheen D, Bukhari S, Haider SR, Nazir A, Khanum S, Shafqat S, Anis MK, Frossard P. Association of phosphodiesterase 4D gene with ischemic stroke in a Pakistani population. Stroke; a Journal of Cerebral Circulation. 36: 2275-7. PMID 16166573 DOI: 10.1161/01.Str.0000182242.59466.Ee  0.338
2005 Saleheen D, Nazir A, Khanum S, Haider SR, Frossard P. A novel mutation in a patient with pantothenate kinase–associated neurodegeneration Canadian Medical Association Journal. 173: 578-579. PMID 16157712 DOI: 10.1503/Cmaj.1050096  0.311
2005 Saeed M, Saleheen D, Siddiqui S, Khan A, Butt ZA, Frossard PM. Association of angiotensin converting enzyme gene polymorphisms with left ventricular hypertrophy. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 28: 345-9. PMID 16138565 DOI: 10.1291/Hypres.28.345  0.322
2005 Ahmad U, Saleheen D, Bokhari A, Frossard PM. Strong association of a renin intronic dimorphism with essential hypertension. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 28: 339-44. PMID 16138564 DOI: 10.1291/Hypres.28.339  0.39
2005 Frossard PM, Bokhari AM, Parvez SH, Lestringant GG. Association of human renin gene haplotype with essential hypertension in an isolated population Biogenic Amines. 19: 79-88. DOI: 10.1163/1569391053722764  0.423
2004 Kureshi N, Ghaffar S, Siddiqui S, Salahuddin I, Frossard PM. Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene. Orl; Journal For Oto-Rhino-Laryngology and Its Related Specialties. 66: 241-5. PMID 15583437 DOI: 10.1159/000081120  0.373
2004 Saeed M, Khan AN, Siddiqui S, Saboohi K, Ali SO, Frossard PM. Association of ACE gene haplotype with essential hypertension. Journal of Human Hypertension. 18: 913-4. PMID 15295612 DOI: 10.1038/Sj.Jhh.1001757  0.385
2004 Iqbal MP, Mahmood S, Mehboobali N, Ishaq M, Fatima T, Parveen S, Frossard P. Association study of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with myocardial infarction. Experimental and Molecular Medicine. 36: 110-115. PMID 15150438 DOI: 10.1038/Emm.2004.16  0.353
2003 Saeed Mahmood M, Saboohi K, Osman Ali S, Bokhari AM, Frossard PM. Association of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with essential hypertension. Journal of Human Hypertension. 17: 719-23. PMID 14504631 DOI: 10.1038/Sj.Jhh.1001600  0.347
2003 Bangash MA, Frossard PM. Editorial comment--The pendulum's swing: the way forward in the genetics of stroke. Stroke; a Journal of Cerebral Circulation. 34: 2516-7. PMID 14500918 DOI: 10.1161/01.Str.0000095191.74929.4B  0.36
2003 Eckl KM, Stevens HP, Lestringant GG, Westenberger-Treumann M, Traupe H, Hinz B, Frossard PM, Stadler R, Leigh IM, Nürnberg P, Reis A, Hennies HC. Mal de Meleda (MDM) caused by mutations in the gene for SLURP-1 in patients from Germany, Turkey, Palestine, and the United Arab Emirates. Human Genetics. 112: 50-6. PMID 12483299 DOI: 10.1007/S00439-002-0838-8  0.317
2003 Saleheen D, Frossard PM. OR-38: Pairwise linkage disequilibrium analysis of the human renin gene American Journal of Hypertension. 16. DOI: 10.1016/S0895-7061(03)00122-5  0.363
2002 Obineche EN, Frossard PM, Bokhari AM. Association between an ANF Gene I/D dimorphism and left ventricular hypertrophy in a Gulf Arab population. Annals of Saudi Medicine. 22: 22-5. PMID 17259761 DOI: 10.5144/0256-4947.2002.22  0.347
2002 Nakano A, Lestringant GG, Paperna T, Bergman R, Gershoni R, Frossard P, Kanaan M, Meneguzzi G, Richard G, Pfendner E, Uitto J, Pulkkinen L, Sprecher E. Junctional epidermolysis bullosa in the Middle East: clinical and genetic studies in a series of consanguineous families. Journal of the American Academy of Dermatology. 46: 510-516. PMID 11907499 DOI: 10.1067/Mjd.2002.119673  0.351
2001 Obineche EN, Frossard PM, Bokhari AM. An association study of five genetic loci and left ventricular hypertrophy amongst Gulf Arabs. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 24: 635-9. PMID 11768721 DOI: 10.1291/Hypres.24.635  0.403
2001 Krebsová A, Küster W, Lestringant GG, Schulze B, Hinz B, Frossard PM, Reis A, Hennies HC. Identification, by homozygosity mapping, of a novel locus for autosomal recessive congenital ichthyosis on chromosome 17p, and evidence for further genetic heterogeneity. American Journal of Human Genetics. 69: 216-22. PMID 11398099 DOI: 10.1086/321284  0.329
2000 Frossard PM, Pravica V, Perrey C, Hutchinson IV, Lukic ML. Lack of association between human TGF-beta1 gene variants and primary hypertension. American Journal of Hypertension. 13: 944-5. PMID 10950405 DOI: 10.1016/S0895-7061(00)00291-0  0.327
1999 Frossard PM, Lestringant GG. Analysis of the apolipoprotein B gene 3' hypervariable region among nationals of the Abu Dhabi Emirate and comparisons with other populations. Annals of Saudi Medicine. 19: 490-4. PMID 17277465 DOI: 10.5144/0256-4947.1999.490  0.352
1999 Frossard PM, Lestringant GG, Malloy MJ, Kane JP. Human renin gene BglI dimorphism associated with hypertension in two independent populations. Clinical Genetics. 56: 428-33. PMID 10665661 DOI: 10.1034/J.1399-0004.1999.560604.X  0.424
1999 Frossard PM, Kane JP, Malloy MJ, Bener A. Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 22: 285-9. PMID 10580395 DOI: 10.1291/Hypres.22.285  0.431
1999 Sprecher E, Lestringant GG, Szargel R, Bergman R, Labay V, Frossard PM, Friedman-Birnbaum R, Cohen N. Atrichia with papular lesions resulting from a nonsense mutation within the human hairless gene. The Journal of Investigative Dermatology. 113: 687-90. PMID 10504459 DOI: 10.1046/J.1523-1747.1999.00723.X  0.35
1999 Frossard PM, Obineche EN, Lestringant GG. Association of an apolipoprotein B gene marker with essential hypertension. Hypertension. 33: 1052-6. PMID 10205247 DOI: 10.1161/01.Hyp.33.4.1052  0.413
1998 Frossard PM, Lestringant GG, Obineche EN, Hill SH. The angiotensin-converting enzyme (ACE) gene insertion/deletion dimorphism tracks with higher serum ace activities in both younger and older subjects. Annals of Saudi Medicine. 18: 389-92. PMID 17344705 DOI: 10.5144/0256-4947.1998.389  0.343
1998 Frossard PM, Girodon E, Dawson KP, Ghanem N, Plassa F, Lestringant GG, Goossens M. Identification of cystic fibrosis mutations in the United Arab Emirates. Mutations in brief no. 133. Online. Human Mutation. 11: 412-3. PMID 10206682 DOI: 10.1002/(Sici)1098-1004(1998)11:5<412::Aid-Humu15>3.0.Co;2-O  0.311
1998 Frossard PM, Hill SH, Elshahat YI, Obineche EN, Bokhari AM, Lestringant GG, John A, Abdulle AM. Associations of angiotensinogen gene mutations with hypertension and myocardial infarction in a gulf population. Clinical Genetics. 54: 285-93. PMID 9831339 DOI: 10.1034/J.1399-0004.1998.5440405.X  0.411
1998 Frossard PM, Lestringant GG, Elshahat YI, John A, Obineche EN. An MboI two-allele polymorphism may implicate the human renin gene in primary hypertension. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 21: 221-5. PMID 9786608 DOI: 10.1291/Hypres.21.221  0.415
1997 Frossard PM, Obineche EN, Lestringant GG, Elshahat YI. Association study between the ANF gene and hypertension in a Gulf Arab population. American Journal of Hypertension. 10: 1308-10. PMID 9397252 DOI: 10.1016/S0895-7061(97)00303-8  0.395
1997 Lestringant GG, Frossard PM, Adeghate E, Qayed KI. Mal de Meleda: a report of four cases from the United Arab Emirates. Pediatric Dermatology. 14: 186-91. PMID 9192409 DOI: 10.1111/J.1525-1470.1997.Tb00234.X  0.327
1997 Frossard PM, Obineche EN, Elshahat YI, Lestringant GG. Deletion polymorphism in the angiotensin-converting enzyme gene is not associated with hypertension in a Gulf Arab population. Clinical Genetics. 51: 211-3. PMID 9137889 DOI: 10.1111/J.1399-0004.1997.Tb02455.X  0.391
1996 Obineche EN, Frossard PM, Elshahat YI, Lestringant GG. Association study of a genetic marker of the human atrial natriuretic peptides (hANP) gene and essential hypertension amongst gulf arabs American Journal of Kidney Diseases. 27. DOI: 10.1016/S0272-6386(96)90218-8  0.371
1995 Frossard PM, Lestringant GG. Association between a dimorphic site on chromosome 12 and clinical diagnosis of hypertension in three independent populations. Clinical Genetics. 48: 284-7. PMID 8835321 DOI: 10.1111/J.1399-0004.1995.Tb04110.X  0.407
1991 Ordovas JM, Civeira F, Genest J, Craig S, Robbins AH, Meade T, Pocovi M, Frossard PM, Masharani U, Wilson PW. Restriction fragment length polymorphisms of the apolipoprotein A-I, C-III, A-IV gene locus. Relationships with lipids, apolipoproteins, and premature coronary artery disease. Atherosclerosis. 87: 75-86. PMID 1678604 DOI: 10.1016/0021-9150(91)90234-T  0.418
1990 Genest JJ, Ordovas JM, McNamara JR, Robbins AM, Meade T, Cohn SD, Salem DN, Wilson PW, Masharani U, Frossard PM. DNA polymorphisms of the apolipoprotein B gene in patients with premature coronary artery disease. Atherosclerosis. 82: 7-17. PMID 1972879 DOI: 10.1016/0021-9150(90)90138-9  0.382
1988 Masharani U, Nakashima PF, Lim DW, Frossard PM. NsiI and ScaI restriction fragment length polymorphisms at the atrial natriuretic peptides (ANP) gene locus. Human Genetics. 80: 307. PMID 2903848 DOI: 10.1007/Bf01790105  0.336
1988 Masharani U, Wolf D, Frossard PM. BanII and ScaI RFLPs at the human p53 gene locus. Nucleic Acids Research. 16: 7757. PMID 2901071 DOI: 10.1093/Nar/16.15.7757  0.347
1988 Coleman RT, Taylor JE, Shine JJ, Frossard PM. Human estrogen receptor (ESR) gene locus: PssI dimorphism. Nucleic Acids Research. 16: 7208. PMID 2900495 DOI: 10.1093/Nar/16.14.7208  0.306
1988 Masharani U, Baxter JD, Frossard PM. Two EcoT14I RFLPs at the human renin (REN) gene locus. Nucleic Acids Research. 16: 6253. PMID 2899876 DOI: 10.1093/Nar/16.13.6253  0.361
1988 Masharani U, Frossard PM. MspI and HindIII restriction fragment length polymorphisms at the human Na,K-ATPase beta-subunit (ATP1B) gene locus. Human Genetics. 80: 308. PMID 2461341 DOI: 10.1007/Bf01790106  0.344
1987 Frossard PM, Coleman RT, Morrison NA. Human natriuretic peptides (ANP) gene locus: BsmI RFLP. Nucleic Acids Research. 15: 7656. PMID 2889195 DOI: 10.1093/Nar/15.18.7656  0.304
1986 Frossard PM, Gonzalez PA, Dillan NA, Coleman RT, Atlas SA. Human renin (REN) gene locus: BglII, RsaI and TaqI RFLPs. Nucleic Acids Research. 14: 6778. PMID 3018680 DOI: 10.1093/Nar/14.16.6778  0.362
1986 Frossard PM, Gonzalez PA, Protter AA, Coleman RT, Funke H, Assmann G. Pvu II RFLP in the 5' of the human apolipoprotein B gene. Nucleic Acids Research. 14: 4373. PMID 3012469 DOI: 10.1093/Nar/14.10.4373  0.305
1986 Frossard PM, Coleman RT. Human atrial natriuretic peptides (ANP) gene locus: BglI RFLP. Nucleic Acids Research. 14: 9223. PMID 2878420 DOI: 10.1093/Nar/14.22.9223  0.301
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