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Robert Lewis Letsinger - Publications

Affiliations: 
Chemistry Northwestern University, Evanston, IL 
Area:
chemical synthesis of DNA
Website:
http://www.northwestern.edu/newscenter/stories/2014/06/pioneer-in-dna-synthesis-dies-at-age-92.html
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84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2002 Li Z, Jin R, Mirkin CA, Letsinger RL. Multiple thiol-anchor capped DNA-gold nanoparticle conjugates. Nucleic Acids Research. 30: 1558-62. PMID 11917016 DOI: 10.1093/Nar/30.7.1558  0.46
2002 Storhoff JJ, Elghanian R, Mirkin CA, Letsinger RL. Sequence-dependent stability of DNA-modified gold nanoparticles Langmuir. 18: 6666-6670. DOI: 10.1021/La0202428  0.432
2001 Park SJ, Lazarides AA, Mirkin CA, Letsinger RL. Directed Assembly of Periodic Materials from Protein and Oligonucleotide-Modified Nanoparticle Building Blocks. Angewandte Chemie (International Ed. in English). 40: 2909-2912. PMID 29711982 DOI: 10.1002/1521-3773(20010803)40:15<2909::Aid-Anie2909>3.0.Co;2-O  0.442
2001 Letsinger RL, Mirkin CA, Park SJ, Viswanadham G, Zhang L. Poly(oligonucleotide) conjugates: applications in assembling nanoparticles and in detecting DNA sequences. Nucleic Acids Research. Supplement (2001). 1-2. PMID 12836234  0.379
2000 Park SJ, Lazarides AA, Mirkin CA, Brazis PW, Kannewurf CR, Letsinger RL. The Electrical Properties of Gold Nanoparticle Assemblies Linked by DNA. Angewandte Chemie (International Ed. in English). 39: 3845-3848. PMID 29711710 DOI: 10.1002/1521-3773(20001103)39:21<3845::Aid-Anie3845>3.0.Co;2-O  0.434
2000 Demers LM, Mirkin CA, Mucic RC, Reynolds RA, Letsinger RL, Elghanian R, Viswanadham G. A fluorescence-based method for determining the surface coverage and hybridization efficiency of thiol-capped oligonucleotides bound to gold thin films and nanoparticles. Analytical Chemistry. 72: 5535-41. PMID 11101228 DOI: 10.1021/Ac0006627  0.431
2000 Taton TA, Mirkin CA, Letsinger RL. Scanometric DNA array detection with nanoparticle probes. Science (New York, N.Y.). 289: 1757-60. PMID 10976070 DOI: 10.1126/Science.289.5485.1757  0.69
2000 Letsinger RL, Elghanian R, Viswanadham G, Mirkin CA. Use of a steroid cyclic disulfide anchor in constructing gold nanoparticle-oligonucleotide conjugates. Bioconjugate Chemistry. 11: 289-91. PMID 10725107 DOI: 10.1021/Bc990152N  0.402
2000 Reynolds RA, Mirkin CA, Letsinger RL. A gold nanoparticle/latex microsphere-based colorimetric oligonucleotide detection method Pure and Applied Chemistry. 72: 229-235. DOI: 10.1351/Pac200072010229  0.439
2000 Taton TA, Mucic RC, Mirkin CA, Letsinger RL. The DNA-mediated formation of supramolecular mono and multilayered nanoparticle structures [10] Journal of the American Chemical Society. 122: 6305-6306. DOI: 10.1021/Ja0007962  0.656
2000 Reynolds RA, Mirkin CA, Letsinger RL. Homogeneous, nanoparticle-based quantitative colorimetric detection of oligonucleotides [13] Journal of the American Chemical Society. 122: 3795-3796. DOI: 10.1021/Ja000133K  0.418
2000 Park SJ, Lazarides AA, Mirkin CA, Brazis PW, Kannewurf CR, Letsinger RL. The electrical properties of gold nanoparticle assemblies linked by DNA Angewandte Chemie - International Edition. 39: 3845-3848. DOI: 10.1002/1521-3773(20001103)39:21<3845::AID-ANIE3845>3.0.CO;2-O  0.353
1999 Letsinger RL, Mirkin CA, Elghanian R, Mucic RC, Storhoff JJ. Chemistry of oligonucleotide-gold nanoparticle conjugates Phosphorus, Sulfur and Silicon and Related Elements. 144: 359-362. DOI: 10.1080/10426509908546255  0.438
1999 Mitchell GP, Mirkin CA, Letsinger RL. Programmed assembly of DNA functionalized quantum dots [10] Journal of the American Chemical Society. 121: 8122-8123. DOI: 10.1021/Ja991662V  0.377
1998 Letsinger RL. Use of oligonucleotide conjugates in creating self-assembling supramolecular systems Nucleosides and Nucleotides. 17: 1861-1869. DOI: 10.1080/07328319808004724  0.324
1998 Mucic RC, Storhoff JJ, Mirkin CA, Letsinger RL. DNA-directed synthesis of binary nanoparticle network materials [5] Journal of the American Chemical Society. 120: 12674-12675. DOI: 10.1021/Ja982721S  0.436
1998 Storhoff JJ, Elghanian R, Mucic RC, Mirkin CA, Letsinger RL. One-pot colorimetric differentiation of polynucleotides with single base imperfections using gold nanoparticle probes Journal of the American Chemical Society. 120: 1959-1964. DOI: 10.1021/Ja972332I  0.435
1997 Elghanian R, Storhoff JJ, Mucic RC, Letsinger RL, Mirkin CA. Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. Science (New York, N.Y.). 277: 1078-81. PMID 9262471 DOI: 10.1126/Science.277.5329.1078  0.441
1997 Letsinger RL, Wu T, Elghanian R. Chemical and photochemical ligation of oligonucleotide blocks Nucleosides and Nucleotides. 16: 643-652. DOI: 10.1080/07328319708002929  0.302
1996 Mirkin CA, Letsinger RL, Mucic RC, Storhoff JJ. A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature. 382: 607-9. PMID 8757129 DOI: 10.1038/382607A0  0.436
1996 Mucic RC, Herrlein MK, Mirkin CA, Letsinger RL. Synthesis and characterization of DNA with ferrocenyl groups attached to their 5′-termini: Electrochemical characterization of a redox-active nucleotide monolayer Chemical Communications. 555-557. DOI: 10.1039/Cc9960000555  0.47
1994 Gryaznov SM, Schultz R, Chaturvedi SK, Letsinger RL. Enhancement of selectivity in recognition of nucleic acids via chemical autoligation. Nucleic Acids Research. 22: 2366-9. PMID 8036165 DOI: 10.1093/Nar/22.12.2366  0.312
1993 Gryaznov SM, Letsinger RL. Template controlled coupling and recombination of oligonucleotide blocks containing thiophosphoryl groups. Nucleic Acids Research. 21: 1403-8. PMID 8464731 DOI: 10.1093/Nar/21.6.1403  0.307
1992 Gryaznov SM, Letsinger RL. Synthesis and properties of oligonucleotides containing aminodeoxythymidine units. Nucleic Acids Research. 20: 3403-9. PMID 1630911 DOI: 10.1093/Nar/20.13.3403  0.325
1992 Gryaznov SM, Letsinger RL. Selective O-phosphitilation with nucleoside phosphoramidite reagents. Nucleic Acids Research. 20: 1879-82. PMID 1579488 DOI: 10.1093/Nar/20.8.1879  0.358
1991 Alul RH, Singman CN, Zhang GR, Letsinger RL. Oxalyl-CPG: a labile support for synthesis of sensitive oligonucleotide derivatives. Nucleic Acids Research. 19: 1527-32. PMID 2027761 DOI: 10.1093/Nar/19.7.1527  0.323
1991 Gryaznov SM, Letsinger RL. Synthesis of oligonucleotides via monomers with unprotected bases Journal of the American Chemical Society. 113: 5876-5877. DOI: 10.1021/Ja00015A059  0.329
1983 Letsinger RL. Chemical Synthesis of Oligodeoxyribonucleotides: A Simplified Procedure Genetic Engineering. 5: 191-207. DOI: 10.1007/978-1-4684-4556-5_10  0.32
1982 Tanaka T, Letsinger RL. Syringe method for stepwise chemical synthesis of oligonucleotides. Nucleic Acids Research. 10: 3249-60. PMID 7099961 DOI: 10.1093/Nar/10.10.3249  0.301
1981 Letsinger RL, Schott ME. Selectivity in binding a phenanthridinium-dinucleotide derivative to homopolynucleotides Journal of the American Chemical Society. 103: 7394-7396. DOI: 10.1021/Ja00414A086  0.724
1977 Wubbels GG, Letsinger RL. Photochemistry of benzaldehyde in hydrochloric acid. Limitation of the scope of photoreduction-chlorination Journal of Organic Chemistry. 42: 1810-1811. DOI: 10.1021/Jo00430A034  0.656
1976 Letsinger RL, Lunsford WB. Synthesis of thymidine oligonucleotides by phosphite triester intermediates. Journal of the American Chemical Society. 98: 3655-61. PMID 1270704 DOI: 10.1002/Chin.197636334  0.33
1976 Letsinger RL, Wilkes JS, Dumas LB. Incorporation of 5′-amino-5′-deoxythymidine 5′-phosphate in polynucleotides by use of DNA polymerase I and a φX174 DNA template Biochemistry. 15: 2810-2816. PMID 779832 DOI: 10.1021/Bi00658A017  0.353
1976 Letsinger RL, Hapke B, Petersen GR, Dumas LB. Enzymatic synthesis of duplex circular phiX174 DNA containing phosphoramidate bonds in the (-) strand. Nucleic Acids Research. 3: 1053-63. PMID 775443 DOI: 10.1093/Nar/3.4.1053  0.304
1975 Greene GL, Letsinger RL. Formation of internucleotide 3'-5' phosphoramidate links by direct coupling of phosphoryl and amino groups. Nucleic Acids Research. 2: 1123-7. PMID 1153331 DOI: 10.1093/Nar/2.7.1123  0.518
1975 Mungall WS, Greene GL, Heavner GA, Letsinger RL. Use of azido group in the synthesis of 5' terminal aminodeoxythymidine oligonucleotides. The Journal of Organic Chemistry. 40: 1569-62. PMID 1142038 DOI: 10.1021/Jo00899A038  0.5
1975 Pless RC, Letsinger RL. Solid support synthesis of oligothymidylates using phosphorochloridates and 1-alkylimidazoles. Nucleic Acids Research. 2: 773-86. PMID 167350 DOI: 10.1093/Nar/2.6.773  0.317
1975 Mungall WS, Greene GL, Heavner GA, Letsinger RL. Use of the azido group in the synthesis of 5′ terminal aminodeoxythymidine oligonucleotides Journal of Organic Chemistry. 40: 1659-1662. DOI: 10.1002/Chin.197536407  0.508
1974 Mungall WS, Greene GL, Miller PS, Letsinger RL. Use of phosphorus oxychloride in synthesizing nucleotides and oligonucleotides. Nucleic Acids Research. 1: 615-27. PMID 10793743 DOI: 10.1093/Nar/1.4.615  0.61
1974 Wubbels GG, Letsinger RL. Photoreactions of nitrobenzene and monosubstituted nitrobenzenes with hydrochloric acid. Evidence concerning the reaction mechanism Journal of the American Chemical Society. 96: 6698-6706. DOI: 10.1021/Ja00828A026  0.672
1973 Wilkes JS, Hapke B, Letsinger RL. A 5'-amino analog of adenosine diphosphate. Biochemical and Biophysical Research Communications. 53: 917-22. PMID 4354453 DOI: 10.1016/0006-291X(73)90179-4  0.313
1972 Letsinger RL, Colb AL. Photo-induced substitution. XI. Photo-induced aromatic substitution, addition, and rearrangement reactions of aromatic ketones Journal of the American Chemical Society. 94: 3665-3667. DOI: 10.1021/Ja00765A088  0.331
1972 LETSINGER RL, COLB AL. ChemInform Abstract: PHOTOINDUZIERTE SUBSTITUTION 11. MITT. PHOTOINDUZIERTE AROMATISCHE SUBSTITUTION, ADDITION UND UMLAGERUNGSRK. VON AROMATISCHEN KETONEN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197232200  0.307
1971 Letsinger RL, Hautala RR. Photoinduced substitution reactions. IX. Effects of micelles on the efficiency of photoinduced substitution reactions and fluorescence quenching The Journal of Organic Chemistry. 36: 3762-3768. DOI: 10.1021/Jo00823A022  0.319
1971 Petersen WC, Letsinger RL. Photoinduced reactions of aromatic nitro compounds with borohydride and cyanide Tetrahedron Letters. 12: 2197-2200. DOI: 10.1016/S0040-4039(01)96818-2  0.326
1969 Letsinger RL, Ogilvie KK, Miller PS. Nucleotide chemistry. XV. Developments in syntheses of oligodeoxyribonucleotides and their organic derivatives Journal of the American Chemical Society. 91: 3360-3365. DOI: 10.1021/Ja01040A044  0.61
1969 Letsinger RL, Miller PS. Nucleotide chemistry. XIV. Protecting groups for nucleosides used in synthesizing oligonucleotides Journal of the American Chemical Society. 91: 3356-3359. DOI: 10.1021/Ja01040A043  0.505
1969 Letsinger RL, Ogilvie KK. Nucleotide chemistry. XIII. Synthesis of oligothymidylates via phosphotriester intermediates Journal of the American Chemical Society. 91: 3350-3355. DOI: 10.1021/Ja01040A042  0.559
1969 Letsinger RL, Steller KE. Photosensitized nucleophilic aromatic substitution Tetrahedron Letters. 10: 1401-1404. DOI: 10.1016/S0040-4039(01)87898-9  0.326
1968 Letsinger RL, Miller PS, Grams GW. Selective N-debenzoylation of N,O-polybenzoylucleosides. Tetrahedron Letters. 2621-4. PMID 5646263 DOI: 10.1016/S0040-4039(00)89658-6  0.424
1968 Ogilvie KK, Letsinger RL. Deaminase activity of commercial spleen phosphodiesterase. Biochemical and Biophysical Research Communications. 30: 273-7. PMID 4296677 DOI: 10.1016/0006-291X(68)90446-4  0.465
1967 Letsinger RL, Caruthers MH, Miller PS, Ogilvie KK. Oligonucleotide syntheses utilizing beta-benzoylpropionyl, a blocking group with a trigger for selective cleavage. Journal of the American Chemical Society. 89: 7146-7. PMID 6064358 DOI: 10.1021/Ja01002A074  0.684
1967 Ogilvie KK, Letsinger RL. Use of isobutyloxycarbonyl as a blocking group in preparation of 3'-O-p-monomethyoxytritylthymidine. The Journal of Organic Chemistry. 32: 2365-6. PMID 6046184 DOI: 10.1021/Jo01282A066  0.507
1967 Letsinger RL, Ogilvie KK. Use of p-nitrophenyl chloroformate in blocking hydroxyl groups in nucleosides. The Journal of Organic Chemistry. 32: 296-300. PMID 6045202 DOI: 10.1021/Jo01288A011  0.507
1967 Letsinger RL, Caruthers MH, Jerina DM. Reactions of nucleosides on polymer supports. Synthesis of thymidylylthymidylylthymidine. Biochemistry. 6: 1379-88. PMID 6036831 DOI: 10.1021/Bi00857A021  0.635
1967 Letsinger RL, Jerina DM. Reactivity of ester groups on insoluble polymer supports Journal of Polymer Science Part a-1: Polymer Chemistry. 5: 1977-1986. DOI: 10.1002/pol.1967.150050814  0.39
1967 Letsinger RL, Ogilvie KK. A convenient method for stepwise synthesis of oligothymidylate derivatives in large-scale quantities [13] Journal of the American Chemical Society. 89: 4801-4802.  0.45
1966 Letsinger RL, Wagner TE. Regulation of Rate of Reaction of a Polyuridylic Acid Derivative by Use of Suppressor and Antisuppressor Molecules1,2 Journal of the American Chemical Society. 88: 2062-2063. DOI: 10.1021/Ja00961A049  0.496
1966 Letsinger RL, Wubbels GG. Photoinduced substitution. IV. Reaction of aromatic nitro compounds with hydrochloric acid [13] Journal of the American Chemical Society. 88: 5041-5042.  0.677
1965 Letsinger RL, Malcolm Smith J, Gilpin J, MacLean DB. Organoboron compounds. XX. Chemistry of some 1-naphthaleneboronic acids with substituents in the 8-position Journal of Organic Chemistry. 30: 807-812. DOI: 10.1021/Jo01014A036  0.31
1964 Letsinger RL, Kornet MJ, Mahadevan V, Jerina DM. Reactions on Polymer Supports Journal of the American Chemical Society. 86: 5163-5165. DOI: 10.1021/ja01077a024  0.402
1964 Letsinger RL, Kornet MJ, Mahadevan V, Jerina DM. Reactions on polymer supports Journal of the American Chemical Society. 86: 5163-5165. DOI: 10.1021/Ja01077A024  0.471
1964 Letsinger RL, Ramsay OB. Photo-Induced Nucleophilic Aromatic Substitution Journal of the American Chemical Society. 86: 1447-1448. DOI: 10.1021/Ja01061A044  0.302
1963 Letsinger RL, MacLean DB. Organoboron compounds. XVI. Coöperative functional group effects in reactions of boronoarylbenzimidazoles Journal of the American Chemical Society. 85: 2230-2236. DOI: 10.1021/Ja00898A009  0.319
1963 Letsinger RL, Morrison JD. Organoboron compounds. XV. Stereochemistry of the reaction of 8-quinolineboronic acid with chloroalcohols Journal of the American Chemical Society. 85: 2227-2229. DOI: 10.1021/Ja00898A008  0.341
1963 Letsinger RL, Dandegaonker S, Vullo WJ, Morrison JD. Organoboron compounds. XIV. Polyfunctional catalysis by 8-quinolineboronic acid Journal of the American Chemical Society. 85: 2223-2227. DOI: 10.1021/Ja00898A007  0.3
1961 Letsinger RL, Feare TE, Savereide TJ, Nazy JR. Organoboron compounds. XIII. Boronic acids with neighboring unsaturated groups Journal of Organic Chemistry. 26: 1271-1273. DOI: 10.1021/Jo01063A069  0.314
1961 Letsinger RL, Jamison JD, Hussey AS. Reactions of 2-benzhydrylphenylacetic acid; a new pyrone synthesis Journal of Organic Chemistry. 26: 97-102. DOI: 10.1021/Jo01060A023  0.341
1961 Letsinger RL, Jamison JD. Synthesis of pyranones and benzofluorenones from ketones and carboxylic acids Journal of the American Chemical Society. 83: 193-198. DOI: 10.1021/Ja01462A038  0.326
1960 Letsinger RL, Vullo WJ. peri-Substituted naphthalenes. IV. The tetrahydro-8-isopropyl-1-naphthoic acids Journal of Organic Chemistry. 25: 1844-1848. DOI: 10.1021/Jo01081A003  0.301
1959 Letsinger RL, Nazy JR. Organoboron compounds. XI. Isomerization of 2,2′-tolandiboronic acid Journal of the American Chemical Society. 81: 3013-3017. DOI: 10.1021/Ja01521A024  0.305
1959 Lansbury PT, Letsinger RL. peri-Substituted naphthalenes. II. A rearrangement involving a 1,5-aryl migration Journal of the American Chemical Society. 81: 940-943. DOI: 10.1021/Ja01513A046  0.504
1959 Letsinger RL, Lansbury PT. Peri-substituted naphthalenes. I. New rearrangement reactions of substituted naphthopyrans Journal of the American Chemical Society. 81: 935-939. DOI: 10.1021/Ja01513A045  0.548
1959 Letsinger RL, Dandegaonker SH. Organoboron compounds. IX. 8-Quinolineboronic acid, its preparation and influence on reactions of chlorohydrins Journal of the American Chemical Society. 81: 498-501. DOI: 10.1021/Ja01511A060  0.352
1956 Letsinger RL, Lasco R. Notes - Reactions of Organometallic Compounds with Pyridazine The Journal of Organic Chemistry. 21: 812-814. DOI: 10.1021/Jo01113A612  0.314
1954 Letsinger RL, Skoog I. Organoboron compounds. II. The preparation of ethylene dialkylborinates by the Grignard reaction Journal of the American Chemical Society. 76: 4174-4176. DOI: 10.1021/Ja01645A036  0.321
1952 Letsinger RL, Traynham JG, Bobko E. The reactions of some organometallic compounds with cyclohexene oxide Journal of the American Chemical Society. 74: 399-401. DOI: 10.1021/Ja01122A033  0.569
1950 Morton AA, Marsh FD, Coombs RD, Lyons AL, Penner SE, Ramsden HE, Baker VB, Little EL, Letsinger RL. Polymerization. XII. The Metalation of Olefins and Dienes and their Use in Alfin Polymerization of Butadiene1 Journal of the American Chemical Society. 72: 3785-3792. DOI: 10.1021/Ja01164A125  0.502
1950 Letsinger RL, Traynham JG. Displacement reactions involving optically active alkyl bromides and organometallic compounds Journal of the American Chemical Society. 72: 849-852. DOI: 10.1021/Ja01158A054  0.574
1948 LETSINGER RL, TRAYNHAM JG. The reaction of allysodium with 2-bromooctane. Journal of the American Chemical Society. 70: 3342-4. PMID 18891855 DOI: 10.1021/Ja01190A036  0.56
1948 Letsinger RL, Traynham JG. The preparation of allyl iodide Journal of the American Chemical Society. 70: 2818. DOI: 10.1021/Ja01188A512  0.573
1947 Morton AA, Magat EE, Letsinger RL. Polymerization. VI. The Alfin Catalysts1a Journal of the American Chemical Society. 69: 950-961. DOI: 10.1021/JA01196A067  0.453
1947 Morton AA, Letsinger RL. Polymerization. V. The Catalytic Polymerization of Butadiene by Phenylsodium and Amylpotassium Journal of the American Chemical Society. 69: 172-176. DOI: 10.1021/JA01193A046  0.446
1945 Morton AA, Letsinger RL. Condensations by Sodium. XXVIII. The Metalation of Sodium and Potassium Phenoxides Journal of the American Chemical Society. 67: 1537-1538. DOI: 10.1021/JA01225A041  0.419
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