Year |
Citation |
Score |
2020 |
Aphasizheva I, Alfonzo J, Carnes J, Cestari I, Cruz-Reyes J, Göringer HU, Hajduk S, Lukeš J, Madison-Antenucci S, Maslov DA, McDermott SM, Ochsenreiter T, Read LK, Salavati R, Schnaufer A, ... ... Simpson L, et al. Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes. Trends in Parasitology. 36: 337-355. PMID 32191849 DOI: 10.1016/J.Pt.2020.01.006 |
0.522 |
|
2015 |
Wong RG, Kazane K, Maslov DA, Rogers K, Aphasizhev R, Simpson L. U-insertion/deletion RNA editing multiprotein complexes and mitochondrial ribosomes in Leishmania tarentolae are located in antipodal nodes adjacent to the kinetoplast DNA. Mitochondrion. 25: 76-86. PMID 26462764 DOI: 10.1016/J.Mito.2015.10.006 |
0.668 |
|
2015 |
Simpson L, Douglass SM, Lake JA, Pellegrini M, Li F. Comparison of the Mitochondrial Genomes and Steady State Transcriptomes of Two Strains of the Trypanosomatid Parasite, Leishmania tarentolae. Plos Neglected Tropical Diseases. 9: e0003841. PMID 26204118 DOI: 10.1371/Journal.Pntd.0003841 |
0.514 |
|
2015 |
Simpson L. The most unlikely places. Rna (New York, N.Y.). 21: 740-1. PMID 25780216 DOI: 10.1261/Rna.050088.115 |
0.522 |
|
2012 |
Eckers E, Cyrklaff M, Simpson L, Deponte M. Mitochondrial protein import pathways are functionally conserved among eukaryotes despite compositional diversity of the import machineries. Biological Chemistry. 393: 513-24. PMID 22628314 DOI: 10.1515/Hsz-2011-0255 |
0.394 |
|
2011 |
Li F, Herrera J, Zhou S, Maslov DA, Simpson L. Trypanosome REH1 is an RNA helicase involved with the 3'-5' polarity of multiple gRNA-guided uridine insertion/deletion RNA editing. Proceedings of the National Academy of Sciences of the United States of America. 108: 3542-7. PMID 21321231 DOI: 10.1073/Pnas.1014152108 |
0.505 |
|
2010 |
Gao G, Rogers K, Li F, Guo Q, Osato D, Zhou SX, Falick AM, Simpson L. Uridine insertion/deletion RNA editing in Trypanosomatids: specific stimulation in vitro of Leishmania tarentolae REL1 RNA ligase activity by the MP63 zinc finger protein. Protist. 161: 489-96. PMID 20138580 DOI: 10.1016/J.Protis.2010.01.001 |
0.676 |
|
2010 |
Simpson L, Aphasizhev R, Lukes J, Cruz-Reyes J. Guide to the nomenclature of kinetoplastid RNA editing: a proposal. Protist. 161: 2-6. PMID 19945343 DOI: 10.1016/J.Protis.2009.10.001 |
0.417 |
|
2009 |
Li F, Ge P, Hui WH, Atanasov I, Rogers K, Guo Q, Osato D, Falick AM, Zhou ZH, Simpson L. Structure of the core editing complex (L-complex) involved in uridine insertion/deletion RNA editing in trypanosomatid mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 106: 12306-10. PMID 19590014 DOI: 10.1073/Pnas.0901754106 |
0.63 |
|
2009 |
Sharma MR, Booth TM, Simpson L, Maslov DA, Agrawal RK. Structure of a mitochondrial ribosome with minimal RNA. Proceedings of the National Academy of Sciences of the United States of America. 106: 9637-42. PMID 19497863 DOI: 10.1073/Pnas.0901631106 |
0.479 |
|
2009 |
Osato D, Rogers K, Guo Q, Li F, Richmond G, Klug F, Simpson L. Uridine insertion/deletion RNA editing in trypanosomatid mitochondria: In search of the editosome. Rna (New York, N.Y.). 15: 1338-44. PMID 19447916 DOI: 10.1261/Rna.1642809 |
0.592 |
|
2009 |
Nebohácová M, Kim CE, Simpson L, Maslov DA. RNA editing and mitochondrial activity in promastigotes and amastigotes of Leishmania donovani. International Journal For Parasitology. 39: 635-44. PMID 19109964 DOI: 10.1016/J.Ijpara.2008.10.015 |
0.525 |
|
2008 |
Jensen RE, Simpson L, Englund PT. What happens when Trypanosoma brucei leaves Africa. Trends in Parasitology. 24: 428-31. PMID 18715829 DOI: 10.1016/J.Pt.2008.06.007 |
0.306 |
|
2007 |
Rogers K, Gao G, Simpson L. Uridylate-specific 3' 5'-exoribonucleases involved in uridylate-deletion RNA editing in trypanosomatid mitochondria. The Journal of Biological Chemistry. 282: 29073-80. PMID 17699520 DOI: 10.1074/Jbc.M704551200 |
0.696 |
|
2007 |
Maslov DA, Simpson L. Strategies of kinetoplastid cryptogene discovery and analysis. Methods in Enzymology. 424: 127-39. PMID 17662839 DOI: 10.1016/S0076-6879(07)24006-6 |
0.413 |
|
2007 |
Maslov DA, Spremulli LL, Sharma MR, Bhargava K, Grasso D, Falick AM, Agrawal RK, Parker CE, Simpson L. Proteomics and electron microscopic characterization of the unusual mitochondrial ribosome-related 45S complex in Leishmania tarentolae. Molecular and Biochemical Parasitology. 152: 203-12. PMID 17292489 DOI: 10.1016/J.Molbiopara.2007.01.012 |
0.374 |
|
2006 |
Kang X, Gao G, Rogers K, Falick AM, Zhou S, Simpson L. Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 13944-9. PMID 16963561 DOI: 10.1073/Pnas.0604476103 |
0.677 |
|
2006 |
Maslov DA, Sharma MR, Butler E, Falick AM, Gingery M, Agrawal RK, Spremulli LL, Simpson L. Isolation and characterization of mitochondrial ribosomes and ribosomal subunits from Leishmania tarentolae. Molecular and Biochemical Parasitology. 148: 69-78. PMID 16600399 DOI: 10.1016/J.Molbiopara.2006.02.021 |
0.37 |
|
2006 |
Simpson L. 14 Uridine Insertion/Deletion RNA Editing as a Paradigm for Site-specific Modifications of RNA Molecules Cold Spring Harbor Monograph Archive. 43: 401-417. DOI: 10.1101/087969739.43.401 |
0.368 |
|
2005 |
Gao G, Simpson AM, Kang X, Rogers K, Nebohacova M, Li F, Simpson L. Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase. Proceedings of the National Academy of Sciences of the United States of America. 102: 4712-7. PMID 15781861 DOI: 10.1073/Pnas.0500553102 |
0.658 |
|
2005 |
Kang X, Rogers K, Gao G, Falick AM, Zhou S, Simpson L. Reconstitution of uridine-deletion precleaved RNA editing with two recombinant enzymes. Proceedings of the National Academy of Sciences of the United States of America. 102: 1017-22. PMID 15657144 DOI: 10.1073/Pnas.0409275102 |
0.682 |
|
2004 |
Aphasizhev R, Aphasizheva I, Simpson L. Multiple terminal uridylyltransferases of trypanosomes. Febs Letters. 572: 15-8. PMID 15304317 DOI: 10.1016/J.Febslet.2004.07.004 |
0.428 |
|
2004 |
Aphasizheva I, Aphasizhev R, Simpson L. RNA-editing terminal uridylyl transferase 1: identification of functional domains by mutational analysis. The Journal of Biological Chemistry. 279: 24123-30. PMID 15060068 DOI: 10.1074/Jbc.M401234200 |
0.457 |
|
2004 |
Simpson L, Aphasizhev R, Gao G, Kang X. Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. Rna (New York, N.Y.). 10: 159-70. PMID 14730014 DOI: 10.1261/Rna.5170704 |
0.467 |
|
2004 |
Nebohácová M, Maslov DA, Falick AM, Simpson L. The effect of RNA interference Down-regulation of RNA editing 3'-terminal uridylyl transferase (TUTase) 1 on mitochondrial de novo protein synthesis and stability of respiratory complexes in Trypanosoma brucei. The Journal of Biological Chemistry. 279: 7819-25. PMID 14681226 DOI: 10.1074/Jbc.M311360200 |
0.496 |
|
2004 |
Kang X, Falick AM, Nelson RE, Gao G, Rogers K, Aphasizhev R, Simpson L. Disruption of the zinc finger motifs in the Leishmania tarentolae LC-4 (=TbMP63) L-complex editing protein affects the stability of the L-complex. The Journal of Biological Chemistry. 279: 3893-9. PMID 14604987 DOI: 10.1074/Jbc.M310185200 |
0.559 |
|
2003 |
Hong M, Simpson L. Genomic organization of Trypanosoma brucei kinetoplast DNA minicircles. Protist. 154: 265-79. PMID 13677453 DOI: 10.1078/143446103322166554 |
0.363 |
|
2003 |
Aphasizhev R, Aphasizheva I, Simpson L. A tale of two TUTases. Proceedings of the National Academy of Sciences of the United States of America. 100: 10617-22. PMID 12954983 DOI: 10.1073/Pnas.1833120100 |
0.531 |
|
2003 |
Sbicego S, Alfonzo JD, Estévez AM, Rubio MA, Kang X, Turck CW, Peris M, Simpson L. RBP38, a novel RNA-binding protein from trypanosomatid mitochondria, modulates RNA stability. Eukaryotic Cell. 2: 560-8. PMID 12796301 DOI: 10.1128/Ec.2.3.560-568.2003 |
0.687 |
|
2003 |
Gao G, Simpson L. Is the Trypanosoma brucei REL1 RNA ligase specific for U-deletion RNA editing, and is the REL2 RNA ligase specific for U-insertion editing? The Journal of Biological Chemistry. 278: 27570-4. PMID 12748175 DOI: 10.1074/Jbc.M303317200 |
0.487 |
|
2003 |
Simpson L, Sbicego S, Aphasizhev R. Uridine insertion/deletion RNA editing in trypanosome mitochondria: a complex business. Rna (New York, N.Y.). 9: 265-76. PMID 12591999 DOI: 10.1261/Rna.2178403 |
0.479 |
|
2003 |
Aphasizhev R, Aphasizheva I, Nelson RE, Gao G, Simpson AM, Kang X, Falick AM, Sbicego S, Simpson L. Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. The Embo Journal. 22: 913-24. PMID 12574127 DOI: 10.1093/Emboj/Cdg083 |
0.493 |
|
2003 |
Aphasizhev R, Aphasizheva I, Nelson RE, Simpson L. A 100-kD complex of two RNA-binding proteins from mitochondria of Leishmania tarentolae catalyzes RNA annealing and interacts with several RNA editing components. Rna (New York, N.Y.). 9: 62-76. PMID 12554877 DOI: 10.1261/Rna.2134303 |
0.465 |
|
2003 |
Kaneko T, Suzuki T, Kapushoc ST, Rubio MA, Ghazvini J, Watanabe K, Simpson L, Suzuki T. Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism. The Embo Journal. 22: 657-67. PMID 12554666 DOI: 10.1093/Emboj/Cdg066 |
0.786 |
|
2002 |
Monzani PS, Alfonzo JD, Simpson L, Oliva G, Thiemann OH. Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase. Biochimica Et Biophysica Acta. 1598: 3-9. PMID 12147338 DOI: 10.1016/S0167-4838(02)00334-5 |
0.313 |
|
2002 |
Crain PF, Alfonzo JD, Rozenski J, Kapushoc ST, McCloskey JA, Simpson L. Modification of the universally unmodified uridine-33 in a mitochondria-imported edited tRNA and the role of the anticodon arm structure on editing efficiency. Rna (New York, N.Y.). 8: 752-61. PMID 12088148 DOI: 10.1017/S1355838202022045 |
0.79 |
|
2002 |
Aphasizhev R, Sbicego S, Peris M, Jang SH, Aphasizheva I, Simpson AM, Rivlin A, Simpson L. Trypanosome mitochondrial 3' terminal uridylyl transferase (TUTase): the key enzyme in U-insertion/deletion RNA editing. Cell. 108: 637-48. PMID 11893335 DOI: 10.1016/S0092-8674(02)00647-5 |
0.503 |
|
2002 |
Kapushoc ST, Alfonzo JD, Simpson L. Differential localization of nuclear-encoded tRNAs between the cytosol and mitochondrion in Leishmania tarentolae. Rna (New York, N.Y.). 8: 57-68. PMID 11871660 DOI: 10.1017/S1355838202012281 |
0.799 |
|
2001 |
Gao G, Kapushoc ST, Simpson AM, Thiemann OH, Simpson L. Guide RNAs of the recently isolated LEM125 strain of Leishmania tarentolae: an unexpected complexity. Rna (New York, N.Y.). 7: 1335-47. PMID 11565754 DOI: 10.1017/S1355838201018076 |
0.785 |
|
2001 |
Aphasizhev R, Simpson L. Isolation and Characterization of a U-specific 3′5′ -Exonuclease from Mitochondria of Leishmania tarentolae Journal of Biological Chemistry. 276: 21280-21284. PMID 11279235 DOI: 10.1074/Jbc.M100297200 |
0.515 |
|
2001 |
Carrillo R, Thiemann OH, Alfonzo JD, Simpson L. Uridine insertion/deletion RNA editing in Leishmania tarentolae mitochondria shows cell cycle dependence Molecular and Biochemical Parasitology. 113: 175-181. PMID 11254966 DOI: 10.1016/S0166-6851(00)00385-6 |
0.317 |
|
2000 |
Kapushoc ST, Alfonzo JD, Rubio MA, Simpson L. End processing precedes mitochondrial importation and editing of tRNAs in Leishmania tarentolae. The Journal of Biological Chemistry. 275: 37907-14. PMID 10993905 DOI: 10.1074/Jbc.M007838200 |
0.787 |
|
2000 |
Rubio MA, Liu X, Yuzawa H, Alfonzo JD, Simpson L. Selective importation of RNA into isolated mitochondria from Leishmania tarentolae. Rna (New York, N.Y.). 6: 988-1003. PMID 10917595 DOI: 10.1017/S1355838200991519 |
0.706 |
|
2000 |
Simpson L, Thiemann OH, Savill NJ, Alfonzo JD, Maslov DA. Evolution of RNA editing in trypanosome mitochondria Proceedings of the National Academy of Sciences of the United States of America. 97: 6986-6993. PMID 10860961 DOI: 10.1073/Pnas.97.13.6986 |
0.502 |
|
1999 |
Maslov DA, Yasuhira S, Simpson L. Phylogenetic affinities of Diplonema within the Euglenozoa as inferred from the SSU rRNA gene and partial COI protein sequences. Protist. 150: 33-42. PMID 10724517 DOI: 10.1016/S1434-4610(99)70007-6 |
0.377 |
|
1999 |
Alfonzo JD, Blanc V, Estévez AM, Rubio MA, Simpson L. C to U editing of the anticodon of imported mitochondrial tRNA(Trp) allows decoding of the UGA stop codon in Leishmania tarentolae. The Embo Journal. 18: 7056-62. PMID 10601027 DOI: 10.1093/Emboj/18.24.7056 |
0.678 |
|
1999 |
Estévez AM, Simpson L. Uridine insertion/deletion RNA editing in trypanosome mitochondria - A review Gene. 240: 247-260. PMID 10580144 DOI: 10.1016/S0378-1119(99)00437-0 |
0.539 |
|
1999 |
Estévez AM, Thiemann OH, Alfonzo JD, Simpson L. T7 RNA polymerase-driven transcription in mitochondria of Leishmania tarentolae and Trypanosoma brucei Molecular and Biochemical Parasitology. 103: 251-259. PMID 10551367 DOI: 10.1016/S0166-6851(99)00139-5 |
0.484 |
|
1999 |
Blanc V, Alfonzo JD, Aphasizhev R, Simpson L. The mitochondrial RNA ligase from Leishmania tarentolae can join RNA molecules bridged by a complementary RNA Journal of Biological Chemistry. 274: 24289-24296. PMID 10446205 DOI: 10.1074/Jbc.274.34.24289 |
0.499 |
|
1999 |
Simpson L, Maslov DA. Evolution of the U-insertion/deletion RNA editing in mitochondria of kinetoplastid protozoa Annals of the New York Academy of Sciences. 870: 190-205. PMID 10415483 DOI: 10.1111/J.1749-6632.1999.Tb08879.X |
0.512 |
|
1999 |
Estévez AM, Kierszenbaum F, Wirtz E, Bringaud F, Grunstein J, Simpson L. Knockout of the glutamate dehydrogenase gene in bloodstream Trypanosoma brucei in culture has no effect on editing of mitochondrial mRNAs Molecular and Biochemical Parasitology. 100: 5-17. PMID 10376989 DOI: 10.1016/S0166-6851(99)00024-9 |
0.496 |
|
1999 |
Kapushoc ST, Simpson L. In vitro uridine insertion RNA editing mediated by cis-acting guide RNAs. Rna (New York, N.Y.). 5: 656-69. PMID 10334336 DOI: 10.1017/S1355838299982250 |
0.793 |
|
1999 |
Simpson L. 22 RNA Editing—An Evolutionary Perspective Cold Spring Harbor Monograph Archive. 37: 585-608. DOI: 10.1101/087969589.37.585 |
0.541 |
|
1998 |
Alfonzo JD, Thiemann OH, Simpson L. Purification and characterization of MAR1. A mitochondrial associated ribonuclease from Leishmania tarentolae Journal of Biological Chemistry. 273: 30003-30011. PMID 9792721 DOI: 10.1074/Jbc.273.45.30003 |
0.542 |
|
1998 |
Aphasizhev R, Karmarkar U, Simpson L. Are tRNAs imported into the mitochondria of kinetoplastid protozoa as 5'-extended precursors? Molecular and Biochemical Parasitology. 93: 73 - 80. PMID 9662029 DOI: 10.1016/S0166-6851(98)00022-X |
0.472 |
|
1998 |
Simpson L. A base called J Proceedings of the National Academy of Sciences of the United States of America. 95: 2037-2038. PMID 9482833 DOI: 10.1073/Pnas.95.5.2037 |
0.301 |
|
1998 |
Simpson L, Wang SH, Thiemann OH, Alfonzo JD, Maslov DA, Avila HA. U-insertion/deletion Edited Sequence Database Nucleic Acids Research. 26: 170-176. PMID 9399827 DOI: 10.1093/Nar/26.1.170 |
0.488 |
|
1998 |
Connell GJ, Simpson L. Role of RNA Structure in RNA Editing Cold Spring Harbor Monograph Archive. 35: 641-667. DOI: 10.1101/087969509.35.641 |
0.44 |
|
1997 |
Alfonzo JD, Thiemann O, Simpson L. The mechanism of U insertion/deletion RNA editing in kinetoplastid mitochondria Nucleic Acids Research. 25: 3751-3759. PMID 9380494 DOI: 10.1093/Nar/25.19.3751 |
0.504 |
|
1997 |
Simpson L, Kretzer F. The mitochondrion in dividing Leishmania tarentolae cells is symmetric and circular and becomes a single asymmetric tubule in non-dividing cells due to division of the kinetoplast portion Molecular and Biochemical Parasitology. 87: 71-78. PMID 9233674 DOI: 10.1016/S0166-6851(97)00044-3 |
0.361 |
|
1997 |
Simpson L. The genomic organization of guide RNA genes in kinetoplastid protozoa: Several conundrums and their solutions Molecular and Biochemical Parasitology. 86: 133-141. PMID 9200120 DOI: 10.1016/S0166-6851(97)00037-6 |
0.472 |
|
1997 |
Bringaud F, Stripecke R, Frech GC, Freedland S, Turck C, Byrne EM, Simpson L. Mitochondrial glutamate dehydrogenase from Leishmania tarentolae is a guide RNA-binding protein Molecular and Cellular Biology. 17: 3915-3923. PMID 9199326 DOI: 10.1128/Mcb.17.7.3915 |
0.494 |
|
1997 |
Peris M, Simpson AM, Grunstein J, Liliental JE, Frech GC, Simpson L. Native gel analysis of ribonucleoprotein complexes from a Leishmania tarentolae mitochondrial extract Molecular and Biochemical Parasitology. 85: 9-24. PMID 9108545 DOI: 10.1016/S0166-6851(96)02795-8 |
0.439 |
|
1997 |
Yasuhira S, Simpson L. Phylogenetic affinity of mitochondria of Euglena gracilis and kinetoplastids using cytochrome oxidase I and hsp60. Journal of Molecular Evolution. 44: 341-7. PMID 9060401 DOI: 10.1007/Pl00006152 |
0.527 |
|
1997 |
Connell GJ, Byrne EM, Simpson L. Guide RNA-independent and guide RNA-dependent uridine insertion into cytochrome b mRNA in a mitochondrial lysate from Leishmania tarentolae. Role of RNA secondary structure Journal of Biological Chemistry. 272: 4212-4218. PMID 9020135 DOI: 10.1074/Jbc.272.7.4212 |
0.501 |
|
1996 |
Byrne EM, Connell GJ, Simpson L. Guide RNA-directed uridine insertion RNA editing in vitro Embo Journal. 15: 6758-6765. PMID 8978701 DOI: 10.1002/J.1460-2075.1996.Tb01065.X |
0.493 |
|
1996 |
Simpson L, Frech GC, Maslov DA. [10] RNA editing in trypanosomatid mitochondria Methods in Enzymology. 264: 99-121. PMID 8965731 DOI: 10.1016/S0076-6879(96)64012-9 |
0.323 |
|
1996 |
Yasuhira S, Simpson L. Guide RNAs and guide RNA genes in the cryptobiid kinetoplastid protozoan, Trypanoplasma borreli. Rna (New York, N.Y.). 2: 1153-60. PMID 8903345 |
0.418 |
|
1996 |
Thiemann OH, Simpson L. Analysis of the 3' uridylylation sites of guide RNAs from Leishmania tarentolae Molecular and Biochemical Parasitology. 79: 229-234. PMID 8855560 DOI: 10.1016/0166-6851(96)02653-9 |
0.429 |
|
1996 |
Frech GC, Simpson L. Uridine insertion into preedited mRNA by a mitochondrial extract from Leishmania tarentolae: Stereochemical evidence for the enzyme cascade model Molecular and Cellular Biology. 16: 4584-4589. PMID 8754859 DOI: 10.1128/Mcb.16.8.4584 |
0.477 |
|
1996 |
Lima BD, Simpson L. Sequence-dependent in vivo importation of tRNAs into the mitochondrion of Leishmania tarentolae. Rna (New York, N.Y.). 2: 429-40. PMID 8665410 |
0.328 |
|
1995 |
Bringaud F, Peyruchaud S, Baltz D, Giroud C, Simpson L, Baltz T. Molecular characterization of the mitochondrial heat shock protein 60 gene from Trypanosoma brucei Molecular and Biochemical Parasitology. 74: 119-123. PMID 8719252 DOI: 10.1016/0166-6851(95)02486-7 |
0.33 |
|
1995 |
Byrne E, Bringaud F, Simpson L. RNA-protein interactions in the ribonucleoprotein T-complexes in a mitochondrial extract from Leishmania tarentolae Molecular and Biochemical Parasitology. 72: 65-76. PMID 8538701 DOI: 10.1016/0166-6851(95)00063-7 |
0.451 |
|
1995 |
Frech GC, Bakalara N, Simpson L, Simpson AM. In vitro RNA editing-like activity in a mitochondrial extract from Leishmania tarentolae Embo Journal. 14: 178-187. PMID 7828590 DOI: 10.1002/J.1460-2075.1995.Tb06988.X |
0.518 |
|
1995 |
Simpson L, Thiemann OH. Sense from nonsense: RNA editing in mitochondria of kinetoplastid protozoa and slime molds Cell. 81: 837-840. PMID 7781060 DOI: 10.1016/0092-8674(95)90003-9 |
0.478 |
|
1995 |
Bringaud F, Peris M, Zen KH, Simpson L. Characterization of two nuclear-encoded protein components of mitochondrial ribonucleoprotein complexes from Leishmania tarentolae Molecular and Biochemical Parasitology. 71: 65-79. PMID 7630384 DOI: 10.1016/0166-6851(95)00023-T |
0.394 |
|
1995 |
Yasuhira S, Simpson L. Minicircle-encoded guide RNAs from Crithidia fasciculata. Rna (New York, N.Y.). 1: 634-43. PMID 7489522 |
0.413 |
|
1995 |
Maslov DA, Simpson L. Evolution of parasitism in kinetoplastid protozoa Parasitology Today. 11: 30-32. DOI: 10.1016/0169-4758(95)80106-5 |
0.331 |
|
1994 |
Maslov DA, Avila HA, Lake JA, Simpson L. Evolution of RNA editing in kinetoplastid protozoa Nature. 368: 345-348. PMID 8127370 DOI: 10.1038/368345A0 |
0.495 |
|
1994 |
Simpson L, Maslov DA. RNA editing and the evolution of parasites Science. 264: 1870-1871. PMID 8009214 DOI: 10.1126/Science.8009214 |
0.42 |
|
1994 |
Thiemann OH, Maslov DA, Simpson L. Disruption of RNA editing in Leishmania tarentolae by the loss of minicircle-encoded guide RNA genes Embo Journal. 13: 5689-5700. PMID 7988566 DOI: 10.1002/J.1460-2075.1994.Tb06907.X |
0.42 |
|
1994 |
Maslov DA, Simpson L. RNA editing and mitochondrial genomic organization in the cryptobiid kinetoplastid protozoan Trypanoplasma borreli Molecular and Cellular Biology. 14: 8174-8182. PMID 7969154 DOI: 10.1128/Mcb.14.12.8174 |
0.503 |
|
1994 |
Maslov DA, Thiemann O, Simpson L. Editing and misediting of transcripts of the kinetoplast maxicircle G5 (ND3) cryptogene in an old laboratory strain of Leishmania tarentolae Molecular and Biochemical Parasitology. 68: 155-159. PMID 7891741 DOI: 10.1016/0166-6851(94)00160-X |
0.476 |
|
1994 |
Simpson L, Maslov DA. Ancient origin of RNA editing in kinetoplastid protozoa Current Opinion in Genetics and Development. 4: 887-894. PMID 7888760 DOI: 10.1016/0959-437X(94)90075-2 |
0.466 |
|
1994 |
Peris M, Frech GC, Simpson AM, Bringaud F, Byrne E, Bakker A, Simpson L. Characterization of two classes of ribonucleoprotein complexes possibly involved in RNA editing from Leishmania tarentolae mitochondria Embo Journal. 13: 1664-1672. PMID 7512500 DOI: 10.1002/J.1460-2075.1994.Tb06430.X |
0.47 |
|
1992 |
von Haeseler A, Blum B, Simpson L, Sturm N, Waterman MS. Computer methods for locating kinetoplastid cryptogenes. Nucleic Acids Research. 20: 2717-24. PMID 1614859 DOI: 10.1093/Nar/20.11.2717 |
0.372 |
|
1992 |
Blum B, Simpson L. Formation of guide RNA/messenger RNA chimeric molecules in vitro, the initial step of RNA editing, is dependent on an anchor sequence. Proceedings of the National Academy of Sciences of the United States of America. 89: 11944-8. PMID 1465424 DOI: 10.1073/Pnas.89.24.11944 |
0.497 |
|
1992 |
Sturm NR, Maslov DA, Blum B, Simpson L. Generation of unexpected editing patterns in Leishmania tarentolae mitochondrial mRNAs: misediting produced by misguiding. Cell. 70: 469-76. PMID 1379520 DOI: 10.1016/0092-8674(92)90171-8 |
0.484 |
|
1992 |
Maslov DA, Simpson L. The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing Cell. 70: 459-467. PMID 1379519 DOI: 10.1016/0092-8674(92)90170-H |
0.362 |
|
1992 |
Maslov DA, Sturm NR, Niner BM, Gruszynski ES, Peris M, Simpson L. An intergenic G-rich region in Leishmania tarentolae kinetoplast maxicircle DNA is a pan-edited cryptogene encoding ribosomal protein S12 Molecular and Cellular Biology. 12: 56-67. PMID 1370342 DOI: 10.1128/Mcb.12.1.56 |
0.385 |
|
1991 |
Avila H, Goncalves AM, Nehme NS, Morel CM, Simpson L. Schizodeme analysis of Trypanosoma cruzi stocks from South and Central America by analysis of PCR-amplified minicircle variable region sequences. Molecular and Biochemical Parasitology. 42: 175-87. PMID 2270100 DOI: 10.1016/0166-6851(90)90160-N |
0.327 |
|
1991 |
Sturm NR, Simpson L. Leishmania tarentolae minicircles of different sequence classes encode single guide RNAs located in the variable region approximately 150 bp from the conserved region. Nucleic Acids Research. 19: 6277-81. PMID 1720240 DOI: 10.1093/Nar/19.22.6277 |
0.397 |
|
1991 |
Blum B, Sturm NR, Simpson AM, Simpson L. Chimeric gRNA-mRNA molecules with oligo(U) tails covalently linked at sites of RNA editing suggest that U addition occurs by transesterification. Cell. 65: 543-50. PMID 1709591 DOI: 10.1016/0092-8674(91)90087-F |
0.482 |
|
1990 |
Campbell DA, Suyama Y, Simpson L. Genomic organisation of nuclear tRNAGly and tRNALeu genes in Trypanosoma brucei. Molecular and Biochemical Parasitology. 37: 257-62. PMID 2608100 DOI: 10.1016/0166-6851(89)90157-6 |
0.413 |
|
1990 |
Sturm NR, Simpson L. Partially edited mRNAs for cytochrome b and subunit III of cytochrome oxidase from Leishmania tarentolae mitochondria: RNA editing intermediates. Cell. 61: 871-8. PMID 2160860 DOI: 10.1016/0092-8674(90)90197-M |
0.495 |
|
1990 |
Simpson L. RNA editing - A novel genetic phenomenon? Science. 250: 512-513. PMID 1700474 DOI: 10.1126/Science.1700474 |
0.389 |
|
1990 |
Blum B, Simpson L. Guide RNAs in kinetoplastid mitochondria have a nonencoded 3' oligo(U) tail involved in recognition of the preedited region. Cell. 62: 391-7. PMID 1695552 DOI: 10.1016/0092-8674(90)90375-O |
0.488 |
|
1990 |
Sturm NR, Simpson L. Kinetoplast DNA minicircles encode guide RNAs for editing of cytochrome oxidase subunit III mRNA. Cell. 61: 879-84. PMID 1693097 DOI: 10.1016/0092-8674(90)90198-N |
0.448 |
|
1990 |
Blum B, Bakalara N, Simpson L. A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell. 60: 189-98. PMID 1688737 DOI: 10.1016/0092-8674(90)90735-W |
0.502 |
|
1989 |
Campbell DA, Spithill TW, Samaras N, Simpson AM, Simpson L. Sequence of a cDNA for the ND1 gene from Leishmania major: potential uridine addition in the polyadenosine tail Molecular and Biochemical Parasitology. 36: 197-199. PMID 2770790 DOI: 10.1016/0166-6851(89)90192-8 |
0.513 |
|
1989 |
Simpson AM, Suyama Y, Dewcs H, Campbell DA, Simpson L. Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small mlnltircje and maxicircle transcripts of unknown function Nucleic Acids Research. 17: 5427-5446. PMID 2762144 DOI: 10.1093/Nar/17.14.5427 |
0.514 |
|
1989 |
Sturm NR, Degrave W, Morel C, Simpson L. Sensitive detection and schizodeme classification of Trypanosoma cruzi cells by amplification of kinetoplast minicircle DNA sequences: use in diagnosis of Chagas' disease. Molecular and Biochemical Parasitology. 33: 205-14. PMID 2565018 DOI: 10.1016/0166-6851(89)90082-0 |
0.313 |
|
1989 |
Shaw JM, Campbell D, Simpson L. Internal frameshifts within the mitochondrial genes for cytochrome oxidase subunit II and maxicircle unidentified reading frame 3 of Leishmania tarentolae are corrected by RNA editing: evidence for translation of the edited cytochrome oxidase subunit II mRNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 6220-4. PMID 2548203 DOI: 10.1073/Pnas.86.16.6220 |
0.64 |
|
1989 |
Shaw JM, Simpson L. Characterization of a protein fraction containing cytochromes b and c1 from mitochondria of Leishmania tarentolae. Experimental Parasitology. 68: 443-9. PMID 2542079 DOI: 10.1016/0014-4894(89)90129-X |
0.489 |
|
1989 |
Hughes DE, Shonekan OA, Simpson L. Structure, genomic organization and transcription of the bifunctional dihydrofolate reductase-thymidylate synthase gene from Crithidia fasciculata. Molecular and Biochemical Parasitology. 34: 155-66. PMID 2540436 DOI: 10.1016/0166-6851(89)90007-8 |
0.402 |
|
1989 |
Simpson L, Shaw J. RNA editing and the mitochondrial cryptogenes of kinetoplastid protozoa. Cell. 57: 355-66. PMID 2470509 DOI: 10.1016/0092-8674(89)90911-2 |
0.579 |
|
1988 |
Simpson L, Shaw J, Campbell D, Bakalara N. RNA editing--a novel RNA processing phenomenon in trypanosome mitochondria. MemóRias Do Instituto Oswaldo Cruz. 83: 243. PMID 3253498 DOI: 10.1590/S0074-02761988000500003 |
0.61 |
|
1988 |
Lake JA, de la Cruz VF, Ferreira PC, Morel C, Simpson L. Evolution of parasitism: kinetoplastid protozoan history reconstructed from mitochondrial rRNA gene sequences. Proceedings of the National Academy of Sciences of the United States of America. 85: 4779-83. PMID 3133662 DOI: 10.1073/Pnas.85.13.4779 |
0.333 |
|
1988 |
Degrave W, Fragoso SP, Britto C, van Heuverswyn H, Kidane GZ, Cardoso MA, Mueller RU, Simpson L, Morel CM. Peculiar sequence organization of kinetoplast DNA minicircles from Trypanosoma cruzi. Molecular and Biochemical Parasitology. 27: 63-70. PMID 2830509 DOI: 10.1016/0166-6851(88)90025-4 |
0.33 |
|
1988 |
Shaw JM, Feagin JE, Stuart K, Simpson L. Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons. Cell. 53: 401-11. PMID 2452696 DOI: 10.1016/0092-8674(88)90160-2 |
0.629 |
|
1988 |
Feagin JE, Shaw JM, Simpson L, Stuart K. Creation of AUG initiation codons by addition of uridines within cytochrome b transcripts of kinetoplastids. Proceedings of the National Academy of Sciences of the United States of America. 85: 539-43. PMID 2448777 DOI: 10.1073/Pnas.85.2.539 |
0.494 |
|
1987 |
Muhich ML, Hughes DE, Simpson AM, Simpson L. The monogenetic kinetoplastid protozoan, Crithidia fasciculate, contains a transcriptionally active, multicopy mini-exon sequence Nucleic Acids Research. 15: 3141-3153. PMID 3562248 DOI: 10.1093/Nar/15.7.3141 |
0.384 |
|
1987 |
Simpson L. The mitochondrial genome of kinetoplastid protozoa: genomic organization, transcription, replication, and evolution Annual Review of Microbiology. 41: 363-382. PMID 2825587 DOI: 10.1146/Annurev.Mi.41.100187.002051 |
0.401 |
|
1986 |
Simpson L. Kinetoplast DNA in trypanosomid flagellates International Review of Cytology. 119-179. PMID 3082787 DOI: 10.1016/S0074-7696(08)61426-6 |
0.339 |
|
1986 |
Hughes DE, Simpson L. Introduction of plasmid DNA into the trypanosomatid protozoan Crithidia fasciculata. Proceedings of the National Academy of Sciences of the United States of America. 83: 6058-62. PMID 3016740 DOI: 10.1073/Pnas.83.16.6058 |
0.326 |
|
1986 |
Muhich ML, Simpson L. Specific cleavage of kinetoplast minicircle DNA from Leishmania tarentolae by mung bean nuclease and identification of several additional minicircle sequence classes Nucleic Acids Research. 14: 5531-5556. PMID 3016649 DOI: 10.1093/Nar/14.13.5531 |
0.332 |
|
1985 |
Hughes D, Simpson L, Kayne PS, Neckelmann N. Autonomous replication sequences in the maxicircle kinetoplast DNA of Leishmania tarentolae. Molecular and Biochemical Parasitology. 13: 263-75. PMID 6396515 DOI: 10.1016/0166-6851(84)90118-X |
0.353 |
|
1985 |
De la Cruz VF, Lake JA, Simpson AM, Simpson L. A minimal ribosomal RNA: Sequence and secondary structure of the 9S kinetoplast ribosomal RNA from Leishmania tarentolae Proceedings of the National Academy of Sciences of the United States of America. 82: 1401-1405. PMID 3856267 DOI: 10.1073/Pnas.82.5.1401 |
0.477 |
|
1985 |
Simpson AM, Neckelmann N, de la Cruz VF, Muhich ML, Simpson L. Mapping and 5′ end determination of kinetoplast maxicircle gene transcripts from Leishmania tarentolae Nucleic Acids Research. 13: 5977-5993. PMID 2994021 DOI: 10.1093/Nar/13.16.5977 |
0.465 |
|
1985 |
Muhich ML, Neckelmann N, Simpson L. The divergent region of the Leishmania tarentolae kinetoplast maxicircle DNA contains a diverse set of repetitive sequences. Nucleic Acids Research. 13: 3241-60. PMID 2987878 DOI: 10.1093/Nar/13.9.3241 |
0.318 |
|
1985 |
de la Cruz VF, Simpson AM, Lake JA, Simpson L. Primary sequence and partial secondary structure of the 12S kinetoplast (mitochondrial) ribosomal RNA from Leishmania tarentolae: Conservation of peptidyl-transferase structural elements Nucleic Acids Research. 13: 2337-2356. PMID 2987850 DOI: 10.1093/Nar/13.7.2337 |
0.458 |
|
1984 |
Kidane GZ, Hughes D, Simpson L. Sequence heterogeneity and anomalous electrophoretic mobility of kinetoplast minicircle DNA from Leishmania tarentolae. Gene. 27: 265-77. PMID 6329906 DOI: 10.1016/0378-1119(84)90071-4 |
0.326 |
|
1983 |
Muhich ML, Simpson L, Simpson AM. Comparison of maxicircle DNAs of Leishmania tarentolae and Trypanosoma brucei Proceedings of the National Academy of Sciences of the United States of America. 80: 4060-4064. PMID 6306661 DOI: 10.1073/Pnas.80.13.4060 |
0.341 |
|
1982 |
Simpson L, Spithill TW, Simpson AM. Identification of maxicircle DNA sequences in Leishmania tarentolae that are homologous to sequences of specific yeast mitochondrial structural genes Molecular and Biochemical Parasitology. 6: 253-264. PMID 6292714 DOI: 10.1016/0166-6851(82)90058-5 |
0.444 |
|
1982 |
Simpson AM, Simpson L, Livingston L. Transcription of the maxicircle kinetoplast DNA of Leishmania tarentolae Molecular and Biochemical Parasitology. 6: 237-252. PMID 6183585 DOI: 10.1016/0166-6851(82)90057-3 |
0.416 |
|
1982 |
Simpson L, Simpson AM, Spithill TW, Livingston L. Sequence Organization of Maxicircle Kinetoplast DNA from Leishmania tarentolae Cold Spring Harbor Monograph Archive. 12: 435-439. DOI: 10.1101/087969145.12.435 |
0.498 |
|
1981 |
Morel C, Simpson L. Characterization of pathogenic trypanosomatidae by restriction endonuclease fingerprinting of kinetoplast DNA minicircles. The American Journal of Tropical Medicine and Hygiene. 29: 1070-4. PMID 6254386 DOI: 10.4269/Ajtmh.1980.29.1070 |
0.3 |
|
1980 |
Simpson AM, Simpson L. Kinetoplast DNA and RNA of Trypanosoma brucei Molecular and Biochemical Parasitology. 2: 93-108. PMID 6162099 DOI: 10.1016/0166-6851(80)90034-1 |
0.448 |
|
1980 |
Simpson L, Simpson AM, Kidane G, Livingston L, Spithill TW. The kinetoplast DNA of the hemoflagellate protozoa. The American Journal of Tropical Medicine and Hygiene. 29: 1053-63. PMID 6159799 DOI: 10.4269/Ajtmh.1980.29.1053 |
0.475 |
|
1979 |
Masuda H, Simpson L, Rosenblatt H, Simpson AM. Restriction map, partial cloning and localization of 9S and 12S kinetoplast RNA genes on the maxicircle component of the kinetoplast DNA of Leishmania tarentolae Gene. 6: 51-73. PMID 383578 DOI: 10.1016/0378-1119(79)90085-4 |
0.418 |
|
1978 |
Cheng D, Simpson L. Isolation and characterization of kinetoplast DNA and RNA of Phytomonas davidi. Plasmid. 1: 297-315. PMID 748951 DOI: 10.1016/0147-619X(78)90047-1 |
0.359 |
|
1978 |
Simpson L, Simpson AM. Kinetoplast RNA of Leishmania tarentolae Cell. 14: 169-178. PMID 667932 DOI: 10.1016/0092-8674(78)90311-2 |
0.506 |
|
1975 |
Braly P, Simpson L, Kretzer F. Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae. The Journal of Protozoology. 21: 782-90. PMID 4217377 DOI: 10.1111/J.1550-7408.1974.Tb03752.X |
0.374 |
|
1973 |
Wesley RD, Simpson L. Studies on kinetoplast DNA III. Kinetic complexity of kinetoplast and nuclear DNA from Leishmania tarentolae Biochimica Et Biophysica Acta. 319: 267-276. PMID 4747081 DOI: 10.1016/0005-2787(73)90165-2 |
0.303 |
|
1972 |
Simpson L. The Kinetoplast of the Hernoflagellates International Review of Cytology. 32: 139-207. DOI: 10.1016/S0074-7696(08)60340-X |
0.35 |
|
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