Cory Abate-Shen - Publications

Affiliations: 
Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Molecular Biology, Cell Biology, Genetics

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 de Almeida FN, Vasciaveo A, Antao AM, Zou M, Di Bernardo M, de Brot S, Rodriguez-Calero A, Chui A, Wang ALE, Floc'h N, Kim JY, Afari SN, Mukhammadov T, Arriaga JM, Lu J, ... ... Abate-Shen C, et al. A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer. Biorxiv : the Preprint Server For Biology. PMID 39253480 DOI: 10.1101/2024.08.24.609538  0.461
2024 Arriaga JM, Ronaldson-Bouchard K, Picech F, Nunes de Almeida F, Afari S, Chhouri H, Vunjak-Novakovic G, Abate-Shen C. Correction: In vivo genome-wide CRISPR screening identifies CITED2 as a driver of prostate cancer bone metastasis. Oncogene. PMID 38627522 DOI: 10.1038/s41388-024-03031-2  0.308
2024 Arriaga JM, Ronaldson-Bouchard K, Picech F, Nunes de Almeida F, Afari S, Chhouri H, Vunjak-Novakovic G, Abate-Shen C. In vivo genome-wide CRISPR screening identifies CITED2 as a driver of prostate cancer bone metastasis. Oncogene. PMID 38454137 DOI: 10.1038/s41388-024-02995-5  0.362
2024 Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Socciarelli F, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Dinalankara W, Jere M, Valencia I, ... ... Abate-Shen C, et al. Distinct mesenchymal cell states mediate prostate cancer progression. Nature Communications. 15: 363. PMID 38191471 DOI: 10.1038/s41467-023-44210-1  0.388
2023 Papachristodoulou A, Heidegger I, Virk RK, Di Bernardo M, Kim JY, Laplaca C, Picech F, Schäfer G, De Castro GJ, Hibshoosh H, Loda M, Klocker H, Rubin MA, Zheng T, Benson MC, ... ... Abate-Shen C, et al. Metformin Overcomes the Consequences of NKX3.1 Loss to Suppress Prostate Cancer Progression. European Urology. PMID 37659962 DOI: 10.1016/j.eururo.2023.07.016  0.412
2023 Li JJ, Vasciaveo A, Karagiannis D, Sun Z, Chen X, Socciarelli F, Frankenstein Z, Zou M, Pannellini T, Chen Y, Gardner K, Robinson BD, de Bono J, Abate-Shen C, Rubin MA, et al. NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer. Biorxiv : the Preprint Server For Biology. PMID 37502956 DOI: 10.1101/2023.07.18.549585  0.399
2023 Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Jere M, Unkenholz C, Alexanderani MK, Khani F, ... ... Abate-Shen C, et al. Distinct mesenchymal cell states mediate prostate cancer progression. Biorxiv : the Preprint Server For Biology. PMID 37034687 DOI: 10.1101/2023.03.29.534769  0.462
2023 Floc'h N, Kinkade CW, Kobayashi T, Aytes A, Lefebvre C, Mitrofanova A, Cardiff RD, Califano A, Shen MM, Abate-Shen C. Editor's Note: Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model. Cancer Research. 83: 1160. PMID 37014043 DOI: 10.1158/0008-5472.CAN-23-0516  0.338
2023 Ouyang X, Jessen WJ, Al-Ahmadie H, Serio AM, Lin Y, Shih WJ, Reuter VE, Scardino PT, Shen MM, Aronow BJ, Vickers AJ, Gerald WL, Abate-Shen C. Editor's Note: Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer. Cancer Research. 83: 1161. PMID 37014042 DOI: 10.1158/0008-5472.CAN-23-0515  0.4
2022 Vasciaveo A, Arriaga JM, Nunes de Almeida F, Zou M, Douglass EF, Picech F, Shibata M, Rodriguez-Calero A, de Brot S, Mitrofanova A, Chua CW, Karan C, Realubit R, Pampou S, Kim JY, ... ... Abate-Shen C, et al. OncoLoop: A network-based precision cancer medicine framework. Cancer Discovery. PMID 36374194 DOI: 10.1158/2159-8290.CD-22-0342  0.334
2022 Abate-Shen C, Nunes de Almeida F. Establishment of the LNCaP Cell Line - The Dawn of an Era for Prostate Cancer Research. Cancer Research. 82: 1689-1691. PMID 35502546 DOI: 10.1158/0008-5472.CAN-22-1065  0.431
2022 Papachristodoulou A, Abate-Shen C. Precision intervention for prostate cancer: Re-evaluating who is at risk. Cancer Letters. 538: 215709. PMID 35490919 DOI: 10.1016/j.canlet.2022.215709  0.36
2021 Lopez-Bujanda ZA, Haffner MC, Chaimowitz MG, Chowdhury N, Venturini NJ, Patel RA, Obradovic A, Hansen CS, Jacków J, Maynard JP, Sfanos KS, Abate-Shen C, Bieberich CJ, Hurley PJ, Selby MJ, et al. Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression. Nature Cancer. 2: 803-818. PMID 35122025 DOI: 10.1038/s43018-021-00227-3  0.335
2021 Park S, Rong L, Owczarek TB, Di Bernardo M, Shoulson RL, Chua CW, Kim JY, Lankarani A, Chakrapani P, Syed T, McKiernan JM, Solit DB, Shen MM, Al-Ahmadie HA, Abate-Shen C. Novel mouse models of bladder cancer identify a prognostic signature associated with risk of disease progression. Cancer Research. PMID 34470779 DOI: 10.1158/0008-5472.CAN-21-1254  0.345
2021 Papachristodoulou A, Rodriguez-Calero A, Panja S, Margolskee E, Virk RK, Milner TA, Pina Martina L, Kim JY, Di Bernardo M, Williams AB, Maliza EA, Caputo JM, Haas C, Wang V, De Castro GJ, ... ... Abate-Shen C, et al. NKX3.1 localization to mitochondria suppresses prostate cancer initiation. Cancer Discovery. PMID 33893149 DOI: 10.1158/2159-8290.CD-20-1765  0.386
2021 Paull EO, Aytes A, Jones SJ, Subramaniam PS, Giorgi FM, Douglass EF, Tagore S, Chu B, Vasciaveo A, Zheng S, Verhaak R, Abate-Shen C, Alvarez MJ, Califano A. A modular master regulator landscape controls cancer transcriptional identity. Cell. PMID 33434495 DOI: 10.1016/j.cell.2020.11.045  0.304
2020 Arriaga JM, Panja S, Alshalalfa M, Zhao J, Zou M, Giacobbe A, Madubata CJ, Yeji Kim J, Rodriguez A, Coleman I, Virk RK, Hibshoosh H, Ertunc O, Ozbek B, Fountain J, ... ... Abate-Shen C, et al. A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance. Nature Cancer. 1: 1082-1096. PMID 34085047 DOI: 10.1038/s43018-020-00125-0  0.401
2020 Leibold J, Ruscetti M, Cao Z, Ho YJ, Baslan T, Zou M, Abida W, Feucht J, Han T, Barriga FM, Tsanov KM, Zamechek L, Kulick A, Amor C, Tian S, ... ... Abate-Shen C, et al. Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis. Cancer Discovery. PMID 32376773 DOI: 10.1158/2159-8290.Cd-19-1242  0.528
2020 Mardis ER, Ribas A, Hait WN, Jaffee EM, Foti M, Abate-Shen C, Albini A, Bernards R, Cruz-Correa MR, Flaherty KT, Greenberg PD, June CH, Knudsen KE, Liu ET, Mills GB, et al. AACR calls on congress to take immediate action against COVID-19 and protect patients with cancer during the pandemic Cancer Discovery. 10: 771-774. PMID 32295764 DOI: 10.1158/2159-8290.Cd-20-0449  0.346
2020 Rong L, Abate-Shen C. Abstract A28: Deregulation of KMT2D promotes squamous differentiation in a mouse model of muscle-invasive bladder cancer Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Bladder19-A28  0.47
2020 Abate-Shen C. Abstract IA12: From mouse to man: Dissecting cancer mechanisms using mouse models Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia12  0.551
2020 Arriaga JM, Panja S, Alshalalfa M, Zhao J, Zou M, Giacobbe A, Madubata CJ, Kim JY, Rodriguez A, Coleman I, Virk RK, Hibshoosh H, Ertunc O, Ozbek B, Fountain J, ... ... Abate-Shen C, et al. A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance Nature Cancer. 1: 1082-1096. DOI: 10.1038/s43018-020-00125-0  0.314
2018 Lippman SM, Abate-Shen C, Colbert Maresso KL, Colditz GA, Dannenberg AJ, Davidson NE, Disis ML, DuBois RN, Szabo E, Giuliano AR, Hait WN, Lee JJ, Kensler TW, Kramer BS, Limburg P, et al. AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health. Cancer Prevention Research (Philadelphia, Pa.). 11: 735-778. PMID 30530635 DOI: 10.1158/1940-6207.Capr-18-0421  0.391
2018 Aytes A, Giacobbe A, Mitrofanova A, Ruggero K, Cyrta J, Arriaga J, Palomero L, Farran-Matas S, Rubin MA, Shen MM, Califano A, Abate-Shen C. NSD2 is a conserved driver of metastatic prostate cancer progression. Nature Communications. 9: 5201. PMID 30518758 DOI: 10.1038/S41467-018-07511-4  0.555
2018 Le Magnen C, Virk RK, Dutta A, Kim JY, Panja S, Lopez-Bujanda ZA, Califano A, Drake CG, Mitrofanova A, Abate-Shen C. Cooperation of loss of and inflammation in prostate cancer initiation. Disease Models & Mechanisms. PMID 30266798 DOI: 10.1242/Dmm.035139  0.547
2018 Abate-Shen C. Prostate Cancer Metastasis - Fueled by Fat? The New England Journal of Medicine. 378: 1643-1645. PMID 29694822 DOI: 10.1056/Nejmcibr1800808  0.515
2018 Arriaga JM, Abate-Shen C. Genetically Engineered Mouse Models of Prostate Cancer in the Postgenomic Era. Cold Spring Harbor Perspectives in Medicine. PMID 29661807 DOI: 10.1101/Cshperspect.A030528  0.522
2018 Lee SH, Hu W, Matulay JT, Silva MV, Owczarek TB, Kim K, Chua CW, Barlow LJ, Kandoth C, Williams AB, Bergren SK, Pietzak EJ, Anderson CB, Benson MC, Coleman JA, ... ... Abate-Shen C, et al. Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer. Cell. 173: 515-528.e17. PMID 29625057 DOI: 10.1016/J.Cell.2018.03.017  0.37
2018 Abate-Shen C, Rubin MA. Decision letter: Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death Elife. DOI: 10.7554/Elife.37294.026  0.315
2018 Arriaga JM, Abate-Shen C. Abstract B01: A genetically engineered mouse model of de novo bone metastasis Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B01  0.442
2018 Zou M, Vasciaveo A, Califano A, Abate-Shen C. Abstract 3017: Identifying drivers for advanced prostate cancer by a transposon-based genetic screen Cancer Research. 78: 3017-3017. DOI: 10.1158/1538-7445.Am2018-3017  0.508
2018 Dutta A, Abate-Shen C. Abstract 2412: The nuclear homeoprotein NKX3.1, has a novel function in the mitochondria in regulation of prostate cancer initiation Cancer Research. 78: 2412-2412. DOI: 10.1158/1538-7445.Am2018-2412  0.463
2017 Zou M, Toivanen R, Mitrofanova A, Floc'h N, Hayati S, Sun Y, Le Magnen C, Chester D, Mostaghel EA, Califano A, Rubin MA, Shen MM, Abate-Shen C. Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-resistant Prostate Cancer. Cancer Discovery. PMID 28411207 DOI: 10.1158/2159-8290.Cd-16-1174  0.492
2017 Dutta A, Panja S, Virk RK, Kim JY, Zott R, Cremers S, Golombos DM, Liu D, Mosquera JM, Mostaghel EA, Barbieri CE, Mitrofanova A, Abate-Shen C. Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition. European Urology. PMID 28385453 DOI: 10.1016/J.Eururo.2017.03.031  0.49
2017 Owczarek TB, Kobayashi T, Ramirez R, Rong L, Puzio-Kuter AM, Iyer G, Teo MY, Sanchez-Vega F, Wang J, Schultz N, Zheng T, Solit DB, Al-Ahmadie HA, Abate-Shen C. ARF confers a context-dependent response to chemotherapy in muscle invasive bladder cancer. Cancer Research. PMID 28082400 DOI: 10.1158/0008-5472.Can-16-2621  0.394
2017 Rong L, Owczarek T, Kobayashi T, Abate-Shen C. Abstract 3175: Context-dependent role of ARF for response to chemotherapy in muscle invasive bladder cancer Cancer Research. 77: 3175-3175. DOI: 10.1158/1538-7445.Am2017-3175  0.336
2017 Ruggero K, Giacobbe A, Mitrofanova A, Calvet A, Palomero L, Pujana M, Califano A, Abate-Shen C, Aytes A. Epigenetic mechanisms and therapeutic opportunities in metastatic castration resistant prostate cancer European Urology Supplements. 16: e249-e250. DOI: 10.1016/S1569-9056(17)30215-4  0.486
2016 Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate-Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science (New York, N.Y.). 352: 1576-80. PMID 27339988 DOI: 10.1126/Science.Aad9512  0.51
2016 Le Magnen C, Dutta A, Abate-Shen C. Optimizing mouse models for precision cancer prevention. Nature Reviews. Cancer. 16: 187-96. PMID 26893066 DOI: 10.1038/Nrc.2016.1  0.404
2016 Santanam U, Banach-Petrosky W, Abate-Shen C, Shen MM, White E, DiPaola RS. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth. Genes & Development. 30: 399-407. PMID 26883359 DOI: 10.1101/Gad.274134.115  0.506
2016 McKiernan JM, Onyeji I, Lascano D, Ahn J, Desai N, Abate-Shen C, Holder DD, RoyChoudhury A, Chang S, DeCastro GJ. A phase I/II study of albumin-bound rapamycin nanoparticles in the treatment of bacillus calmette-guerin refractory non-muscle invasive transitional cell bladder cancer. Journal of Clinical Oncology. 34: e16008-e16008. DOI: 10.1200/Jco.2016.34.15_Suppl.E16008  0.33
2016 Zou M, Toivanen R, Mitrofanova A, Shen MM, Abate-Shen C. Abstract 4387: Alterations of TP53 mediate resistance to abiraterone in castration-resistant prostate cancer Cancer Research. 76: 4387-4387. DOI: 10.1158/1538-7445.Am2016-4387  0.423
2016 Magnen CL, Dutta A, Mitrofanova A, Califano A, Abate-Shen C. Abstract 2888: Identification of an NKX3.1-G9a-UTY regulatory network that controls proper prostate differentiation Cancer Research. 76: 2888-2888. DOI: 10.1158/1538-7445.Am2016-2888  0.533
2015 Mitrofanova A, Aytes A, Zou M, Shen MM, Abate-Shen C, Califano A. Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models. Cell Reports. PMID 26387954 DOI: 10.1016/J.Celrep.2015.08.051  0.463
2015 Kobayashi T, Owczarek TB, McKiernan JM, Abate-Shen C. Modelling bladder cancer in mice: opportunities and challenges. Nature Reviews. Cancer. 15: 42-54. PMID 25533675 DOI: 10.1038/Nrc3858  0.417
2015 Magnen CL, Dutta A, Abate-Shen C. Abstract 88: The Nkx3.1 homeobox gene maintains prostatic identity while its loss leads to prostate cancer initiation Cancer Research. 75: 88-88. DOI: 10.1158/1538-7445.Am2015-88  0.531
2014 Wang J, Abate-Shen C. Analyses of tumor-suppressor genes in germline mouse models of cancer. Cold Spring Harbor Protocols. 2014: 807-12. PMID 25086022 DOI: 10.1101/Pdb.Top069773  0.403
2014 Aytes A, Mitrofanova A, Lefebvre C, Alvarez MJ, Castillo-Martin M, Zheng T, Eastham JA, Gopalan A, Pienta KJ, Shen MM, Califano A, Abate-Shen C. Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy. Cancer Cell. 25: 638-51. PMID 24823640 DOI: 10.1016/J.Ccr.2014.03.017  0.537
2014 Abate-Shen C. Abstract IA5: Using cross-species analysis of genome-wide regulatory networks to identify drivers of cancer malignancy Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Ia5  0.505
2014 Wang J, Aytes A, Abate-Shen C. Abstract B45: Combinatorial activation of PI3-kinase and Ras-Raf signaling in mouse models of advanced prostate cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B45  0.485
2014 Mitrofanova A, Floch N, Aytes A, Shen M, Abate-Shen C, Califano A. Abstract A29: Interrogating therapeutic response for advanced prostate cancer in vivo using cross-species regulatory models Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-A29  0.529
2014 Irshad S, Bansal M, Magnen CL, Dillon R, Castillo-Martin M, Zheng T, Aytes A, Wenske S, Guarnieri P, Sumazin P, Benson M, Shen MM, Califano A, Abate-Shen C. Abstract 2873: A molecular signature predictive of indolent prostate cancer Cancer Research. 74: 2873-2873. DOI: 10.1158/1538-7445.Am2014-2873  0.508
2014 Kobayashi T, Ogawa O, Abate-Shen C. Abstract 1575: ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation Cancer Research. 74: 1575-1575. DOI: 10.1158/1538-7445.Am2014-1575  0.364
2013 Abate-Shen C, Pandolfi PP. Effective utilization and appropriate selection of genetically engineered mouse models for translational integration of mouse and human trials. Cold Spring Harbor Protocols. 2013. PMID 24173311 DOI: 10.1101/Pdb.Top078774  0.356
2013 Sawyers CL, Abate-Shen C, Anderson KC, Barker A, Baselga J, Berger NA, Foti M, Jemal A, Lawrence TS, Li CI, Mardis ER, Neumann PJ, Pardoll DM, Prendergast GC, et al. AACR Cancer Progress Report 2013. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: S4-98. PMID 24045178 DOI: 10.1158/1078-0432.Ccr-13-2107  0.329
2013 Irshad S, Bansal M, Castillo-Martin M, Zheng T, Aytes A, Wenske S, Le Magnen C, Guarnieri P, Sumazin P, Benson MC, Shen MM, Califano A, Abate-Shen C. A molecular signature predictive of indolent prostate cancer. Science Translational Medicine. 5: 202ra122. PMID 24027026 DOI: 10.1126/Scitranslmed.3006408  0.472
2013 Aytes A, Mitrofanova A, Kinkade CW, Lefebvre C, Lei M, Phelan V, LeKaye HC, Koutcher JA, Cardiff RD, Califano A, Shen MM, Abate-Shen C. ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: E3506-15. PMID 23918374 DOI: 10.1073/Pnas.1303558110  0.505
2013 Kobayashi T, Wang J, Al-Ahmadie H, Abate-Shen C. ARF regulates the stability of p16 protein via REGγ-dependent proteasome degradation. Molecular Cancer Research : McR. 11: 828-33. PMID 23817020 DOI: 10.1158/1541-7786.Mcr-13-0207  0.312
2013 Kruithof-de Julio M, Shibata M, Desai N, Reynon M, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM. Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 1160-71. PMID 23813564 DOI: 10.1002/Dvdy.24008  0.455
2013 Delto JC, Kobayashi T, Benson M, McKiernan J, Abate-Shen C. Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression. Oncotarget. 4: 269-76. PMID 23563166 DOI: 10.18632/Oncotarget.852  0.382
2013 Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD. ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity. Molecular Cancer Research : McR. 11: 736-47. PMID 23538858 DOI: 10.1158/1541-7786.Mcr-12-0618  0.558
2013 Wang ZA, Mitrofanova A, Bergren SK, Abate-Shen C, Cardiff RD, Califano A, Shen MM. Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity. Nature Cell Biology. 15: 274-83. PMID 23434823 DOI: 10.1038/Ncb2697  0.461
2013 Irshad S, Abate-Shen C. Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic. Cancer Metastasis Reviews. 32: 109-22. PMID 23114843 DOI: 10.1007/S10555-012-9409-1  0.526
2013 Mitrofanova A, Aytes A, Lefebvre C, Shen M, Abate-Shen C, Califano A. Abstract A26: Cross-species analysis of genome-wide regulatory models elucidates master regulators of prostate cancer progression and treatment response Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A26  0.534
2012 Floc'h N, Abate-Shen C. The promise of dual targeting Akt/mTOR signaling in lethal prostate cancer. Oncotarget. 3: 1483-4. PMID 23242005 DOI: 10.18632/Oncotarget.771  0.494
2012 Wang J, Kobayashi T, Floc'h N, Kinkade CW, Aytes A, Dankort D, Lefebvre C, Mitrofanova A, Cardiff RD, McMahon M, Califano A, Shen MM, Abate-Shen C. B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer. Cancer Research. 72: 4765-76. PMID 22836754 DOI: 10.1158/0008-5472.Can-12-0820  0.465
2012 Floc'h N, Kinkade CW, Kobayashi T, Aytes A, Lefebvre C, Mitrofanova A, Cardiff RD, Califano A, Shen MM, Abate-Shen C. Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model. Cancer Research. 72: 4483-93. PMID 22815528 DOI: 10.1158/0008-5472.Can-12-0283  0.471
2012 Wang J, Abate-Shen C. The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells. Plos One. 7: e37647. PMID 22629437 DOI: 10.1371/Journal.Pone.0037647  0.331
2012 Wang J, Abate-Shen C. Transcriptional repression by the Msx1 homeoprotein is associated with global redistribution of the H3K27me3 repressive mark to the nuclear periphery. Nucleus (Austin, Tex.). 3: 155-61. PMID 22555601 DOI: 10.4161/Nucl.19477  0.323
2012 Aytes A, Mitrofanova A, Lefebvre C, Shen MM, Califano A, Abate-Shen C. Abstract A36: Identification of master regulators driving advanced prostate cancer and treatment response through the assembly of mouse and human prostate cancer interactomes Cancer Research. 72: A36-A36. DOI: 10.1158/1538-7445.Prca2012-A36  0.551
2012 Aytes A, Mitrofanova A, Lefebvre C, Kinkade CW, Shen MM, Califano A, Abate-Shen C. Abstract LB-405: Identification of master regulators driving advanced prostate cancer and treatment response through the assembly of mouse and human prostate cancer interactomes Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2012-Lb-405  0.517
2012 Kobayashi T, Delto JC, Abate-Shen C. Abstract 802: A key role for ARF in drug resistance in invasive bladder cancer Cancer Research. 72: 802-802. DOI: 10.1158/1538-7445.Am2012-802  0.441
2012 Kobayashi T, Delto J, Abate-Shen C. 554 A KEY ROLE FOR ARF IN DRUG RESISTANCE IN INVASIVE BLADDER CANCER Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.629  0.436
2011 Wang J, Kumar RM, Biggs VJ, Lee H, Chen Y, Kagey MH, Young RA, Abate-Shen C. The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during Development. Developmental Cell. 21: 575-88. PMID 21852201 DOI: 10.1016/J.Devcel.2011.07.003  0.342
2011 Abate-Shen C, Meneses AA, Kinkade CW, Mitrofanova A, Lefebvre C, Chua CW, Castillo-Martin M, Gelmann E, Shen MM, Califano A. Abstract SY22-01: Interrogating gene expression programs from preclinical analyses of genetically engineered mouse models Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy22-01  0.545
2011 Wang F, McKeehan WL, Shen MM, Abate-Shen C. Genetically engineered mouse models in prostate cancer research Recent Advances in Prostate Cancer: Basic Science Discoveries and Clinical Advances. 219-282. DOI: 10.1142/9789814329460_0009  0.362
2011 Shen MM, Wang Z, Wang X, Kruithof-de Julio M, Lei M, Chua CW, Abate-Shen C. Stem cells in prostate regeneration and cancer Developmental Biology. 356: 120. DOI: 10.1016/J.Ydbio.2011.05.063  0.469
2011 Kobayashi T, Delto J, Castillo-Martin M, Puzio-Kuter A, Cordon-Cardo C, Abate-Shen C. 367 NOVEL P53-INDEPENDENT FUNCTIONS OF ARF IN THE CONTEXT OF COMBINED FUNCTINAL LOSS OF P53 AND PTEN IN A MOUSE MODEL OF INVASIVE BLADDER CANCER Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.453  0.355
2010 Shen MM, Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes & Development. 24: 1967-2000. PMID 20844012 DOI: 10.1101/Gad.1965810  0.514
2010 Patel T, Hruby G, Abate-Shen C, Badani K, Mckiernan J. 259 THE IMPACT OF DIABETES AND METFORMIN USE IN CLINICALLY LOCALIZED PROSTATE CANCER TREATED BY RADICAL PROSTATECTOMY Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.318  0.423
2009 Seager CM, Puzio-Kuter AM, Patel T, Jain S, Cordon-Cardo C, Mc Kiernan J, Abate-Shen C. Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer. Cancer Prevention Research (Philadelphia, Pa.). 2: 1008-14. PMID 19952358 DOI: 10.1158/1940-6207.Capr-09-0169  0.41
2009 Wang X, Kruithof-de Julio M, Economides KD, Walker D, Yu H, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature. 461: 495-500. PMID 19741607 DOI: 10.1038/Nature08361  0.492
2009 Couto SS, Cao M, Duarte PC, Banach-Petrosky W, Wang S, Romanienko P, Wu H, Cardiff RD, Abate-Shen C, Cunha GR. Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer. Differentiation; Research in Biological Diversity. 77: 103-11. PMID 19281769 DOI: 10.1016/J.Diff.2008.09.010  0.502
2009 Puzio-Kuter AM, Castillo-Martin M, Kinkade CW, Wang X, Shen TH, Matos T, Shen MM, Cordon-Cardo C, Abate-Shen C. Inactivation of p53 and Pten promotes invasive bladder cancer. Genes & Development. 23: 675-80. PMID 19261747 DOI: 10.1101/Gad.1772909  0.411
2009 Abate-Shen C, Shen MM. Diagnostics: The prostate-cancer metabolome. Nature. 457: 799-800. PMID 19212391 DOI: 10.1038/457799A  0.515
2008 Shen MM, Wang X, Economides KD, Walker D, Abate-Shen C. Progenitor cells for the prostate epithelium: roles in development, regeneration, and cancer. Cold Spring Harbor Symposia On Quantitative Biology. 73: 529-38. PMID 19150960 DOI: 10.1101/Sqb.2008.73.050  0.504
2008 Abate-Shen C, Brown PH, Colburn NH, Gerner EW, Green JE, Lipkin M, Nelson WG, Threadgill D. The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges. Cancer Prevention Research (Philadelphia, Pa.). 1: 161-6. PMID 19138951 DOI: 10.1158/1940-6207.Capr-08-0076  0.362
2008 Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L. BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. Plos One. 3: e3949. PMID 19079609 DOI: 10.1371/Journal.Pone.0003949  0.513
2008 Wang X, Desai N, Hu YP, Price SM, Abate-Shen C, Shen MM. Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2963-72. PMID 18816836 DOI: 10.1002/Dvdy.21694  0.484
2008 Kinkade CW, Castillo-Martin M, Puzio-Kuter A, Yan J, Foster TH, Gao H, Sun Y, Ouyang X, Gerald WL, Cordon-Cardo C, Abate-Shen C. Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. The Journal of Clinical Investigation. 118: 3051-64. PMID 18725989 DOI: 10.1172/Jci34764  0.509
2008 Abate-Shen C, Shen MM, Gelmann E. Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis. Differentiation; Research in Biological Diversity. 76: 717-27. PMID 18557759 DOI: 10.1111/J.1432-0436.2008.00292.X  0.514
2008 Ouyang X, Jessen WJ, Al-Ahmadie H, Serio AM, Lin Y, Shih WJ, Reuter VE, Scardino PT, Shen MM, Aronow BJ, Vickers AJ, Gerald WL, Abate-Shen C. Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer. Cancer Research. 68: 2132-44. PMID 18381418 DOI: 10.1158/0008-5472.Can-07-6055  0.537
2008 Pienta KJ, Abate-Shen C, Agus DB, Attar RM, Chung LW, Greenberg NM, Hahn WC, Isaacs JT, Navone NM, Peehl DM, Simons JW, Solit DB, Soule HR, VanDyke TA, Weber MJ, et al. The current state of preclinical prostate cancer animal models. The Prostate. 68: 629-39. PMID 18213636 DOI: 10.1002/Pros.20726  0.515
2008 Abate-Shen C, Kinkade C, Castillo-Martin M, Cordon-Cardo C. 7 INVITED Developing combination therapies for hormone-refractory prostate cancer in a pre-clinical mouse model of the disease European Journal of Cancer Supplements. 6: 7. DOI: 10.1016/S1359-6349(08)71939-6  0.352
2007 Abate-Shen C, Shen MM. FGF signaling in prostate tumorigenesis--new insights into epithelial-stromal interactions. Cancer Cell. 12: 495-7. PMID 18068626 DOI: 10.1016/J.Ccr.2007.11.021  0.505
2007 Banach-Petrosky W, Jessen WJ, Ouyang X, Gao H, Rao J, Quinn J, Aronow BJ, Abate-Shen C. Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; Pten mutant mice. Cancer Research. 67: 9089-96. PMID 17909013 DOI: 10.1158/0008-5472.Can-07-2887  0.506
2007 Shen MM, Abate-Shen C. Pten inactivation and the emergence of androgen-independent prostate cancer. Cancer Research. 67: 6535-8. PMID 17638861 DOI: 10.1158/0008-5472.Can-07-1271  0.497
2006 Banach-Petrosky W, Ouyang X, Gao H, Nader K, Ji Y, Suh N, DiPaola RS, Abate-Shen C. Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1;Pten mutant mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5895-901. PMID 17020998 DOI: 10.1158/1078-0432.Ccr-06-1039  0.433
2006 Abate-Shen C. A new generation of mouse models of cancer for translational research. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5274-6. PMID 17000659 DOI: 10.1158/1078-0432.Ccr-06-0500  0.39
2006 Gao H, Ouyang X, Banach-Petrosky WA, Gerald WL, Shen MM, Abate-Shen C. Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 103: 14477-82. PMID 16973750 DOI: 10.1073/Pnas.0606836103  0.506
2006 Gao H, Ouyang X, Banach-Petrosky WA, Shen MM, Abate-Shen C. Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice. Cancer Research. 66: 7929-33. PMID 16912166 DOI: 10.1158/0008-5472.Can-06-1637  0.512
2006 Lee H, Quinn JC, Prasanth KV, Swiss VA, Economides KD, Camacho MM, Spector DL, Abate-Shen C. PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein. Genes & Development. 20: 784-94. PMID 16600910 DOI: 10.1101/Gad.1392006  0.336
2005 Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis. Cancer Research. 65: 6773-9. PMID 16061659 DOI: 10.1158/0008-5472.Can-05-1948  0.466
2005 Abate-Shen C, Shen MM. An unusual gene dosage effect of p27kip1 in a mouse model of prostate cancer. Cell Cycle (Georgetown, Tex.). 4: e45-7. PMID 15701964 DOI: 10.4161/Cc.4.3.1530  0.538
2005 Kuzmichev A, Margueron R, Vaquero A, Preissner TS, Scher M, Kirmizis A, Ouyang X, Brockdorff N, Abate-Shen C, Farnham P, Reinberg D. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 1859-64. PMID 15684044 DOI: 10.1073/Pnas.0409875102  0.409
2004 Gao H, Ouyang X, Banach-Petrosky W, Borowsky AD, Lin Y, Kim M, Lee H, Shih WJ, Cardiff RD, Shen MM, Abate-Shen C. A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 17204-9. PMID 15569926 DOI: 10.1073/Pnas.0407693101  0.483
2004 Lee H, Habas R, Abate-Shen C. MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science (New York, N.Y.). 304: 1675-8. PMID 15192231 DOI: 10.1126/Science.1098096  0.344
2004 Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM. Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Developmental Biology. 267: 387-98. PMID 15013801 DOI: 10.1016/J.Ydbio.2003.11.018  0.463
2004 Rouzankina I, Abate-Shen C, Niswander L. Dlx genes integrate positive and negative signals during feather bud development. Developmental Biology. 265: 219-33. PMID 14697365 DOI: 10.1016/J.Ydbio.2003.09.023  0.333
2003 Abate-Shen C. Homeobox genes and cancer: new OCTaves for an old tune. Cancer Cell. 4: 329-30. PMID 14667497 DOI: 10.1016/S1535-6108(03)00277-0  0.402
2003 Shen MM, Abate-Shen C. Roles of the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 228: 767-78. PMID 14648854 DOI: 10.1002/Dvdy.10397  0.499
2003 Bendall AJ, Hu G, Levi G, Abate-Shen C. Dlx5 regulates chondrocyte differentiation at multiple stages. The International Journal of Developmental Biology. 47: 335-44. PMID 12895028 DOI: 10.1387/Ijdb.12895028  0.556
2003 Abate-Shen C, Banach-Petrosky WA, Sun X, Economides KD, Desai N, Gregg JP, Borowsky AD, Cardiff RD, Shen MM. Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Cancer Research. 63: 3886-90. PMID 12873978  0.333
2002 Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nature Reviews. Cancer. 2: 777-85. PMID 12360280 DOI: 10.1038/Nrc907  0.442
2002 Park JH, Walls JE, Galvez JJ, Kim M, Abate-Shen C, Shen MM, Cardiff RD. Prostatic intraepithelial neoplasia in genetically engineered mice. The American Journal of Pathology. 161: 727-35. PMID 12163397 DOI: 10.1016/S0002-9440(10)64228-9  0.392
2002 Abate-Shen C, Shen MM. Mouse models of prostate carcinogenesis. Trends in Genetics : Tig. 18: S1-5. PMID 12047956 DOI: 10.1016/S0168-9525(02)02683-5  0.474
2002 Kim MJ, Bhatia-Gaur R, Banach-Petrosky WA, Desai N, Wang Y, Hayward SW, Cunha GR, Cardiff RD, Shen MM, Abate-Shen C. Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Research. 62: 2999-3004. PMID 12036903  0.417
2002 Kim MJ, Cardiff RD, Desai N, Banach-Petrosky WA, Parsons R, Shen MM, Abate-Shen C. Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 2884-9. PMID 11854455 DOI: 10.1073/Pnas.042688999  0.505
2001 Hu G, Lee H, Price SM, Shen MM, Abate-Shen C. Msx homeobox genes inhibit differentiation through upregulation of cyclin D1. Development (Cambridge, England). 128: 2373-84. PMID 11493556  0.526
2000 Abate-Shen C, Shen MM. Molecular genetics of prostate cancer. Genes & Development. 14: 2410-34. PMID 11018010 DOI: 10.1101/Gad.819500  0.517
2000 Bendall AJ, Abate-Shen C. Roles for Msx and Dlx homeoproteins in vertebrate development. Gene. 247: 17-31. PMID 10773441 DOI: 10.1016/S0378-1119(00)00081-0  0.364
2000 Yan YT, Stein SM, Ding J, Shen MM, Abate-Shen C. A novel PF/PN motif inhibits nuclear localization and DNA binding activity of the ESX1 homeoprotein. Molecular and Cellular Biology. 20: 661-71. PMID 10611245 DOI: 10.1128/Mcb.20.2.661-671.2000  0.362
1999 Bendall AJ, Ding J, Hu G, Shen MM, Abate-Shen C. Msx1 antagonizes the myogenic activity of Pax3 in migrating limb muscle precursors. Development (Cambridge, England). 126: 4965-76. PMID 10529415  0.521
1999 Bhatia-Gaur R, Donjacour AA, Sciavolino PJ, Kim M, Desai N, Young P, Norton CR, Gridley T, Cardiff RD, Cunha GR, Abate-Shen C, Shen MM. Roles for Nkx3.1 in prostate development and cancer. Genes & Development. 13: 966-77. PMID 10215624 DOI: 10.1101/Gad.13.8.966  0.511
1998 Sciavolino PJ, Abate-Shen C. Molecular biology of prostate development and prostate cancer. Annals of Medicine. 30: 357-68. PMID 9783834 DOI: 10.3109/07853899809029935  0.514
1998 Yang L, Zhang H, Hu G, Wang H, Abate-Shen C, Shen MM. An early phase of embryonic Dlx5 expression defines the rostral boundary of the neural plate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8322-30. PMID 9763476 DOI: 10.1523/Jneurosci.18-20-08322.1998  0.543
1998 Hu G, Vastardis H, Bendall AJ, Wang Z, Logan M, Zhang H, Nelson C, Stein S, Greenfield N, Seidman CE, Seidman JG, Abate-Shen C. Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis. Molecular and Cellular Biology. 18: 6044-51. PMID 9742121 DOI: 10.1128/Mcb.18.10.6044  0.534
1997 He WW, Sciavolino PJ, Wing J, Augustus M, Hudson P, Meissner PS, Curtis RT, Shell BK, Bostwick DG, Tindall DJ, Gelmann EP, Abate-Shen C, Carter KC. A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer Genomics. 43: 69-77. PMID 9226374 DOI: 10.1006/geno.1997.4715  0.427
1997 Sciavolino PJ, Abrams EW, Yang L, Austenberg LP, Shen MM, Abate-Shen C. Tissue-specific expression of murine Nkx3.1 in the male urogenital system Developmental Dynamics. 209: 127-138. PMID 9142502 DOI: 10.1002/(Sici)1097-0177(199705)209:1<127::Aid-Aja12>3.0.Co;2-Z  0.418
1997 Zhang H, Hu G, Wang H, Sciavolino P, Iler N, Shen MM, Abate-Shen C. Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism. Molecular and Cellular Biology. 17: 2920-32. PMID 9111364 DOI: 10.1128/Mcb.17.5.2920  0.549
1996 Catron KM, Wang H, Hu G, Shen MM, Abate-Shen C. Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy. Mechanisms of Development. 55: 185-99. PMID 8861098 DOI: 10.1016/0925-4773(96)00503-5  0.538
1996 Zhang H, Catron KM, Abate-Shen C. A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression. Proceedings of the National Academy of Sciences of the United States of America. 93: 1764-9. PMID 8700832 DOI: 10.1073/Pnas.93.5.1764  0.324
1996 Schnabel CA, Abate-Shen C. Repression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residues. Molecular and Cellular Biology. 16: 2678-88. PMID 8649375 DOI: 10.1128/Mcb.16.6.2678  0.31
1995 Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C. A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Mechanisms of Development. 53: 87-96. PMID 8555114 DOI: 10.1016/0925-4773(95)00427-0  0.322
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