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Christopher T. Seto - Publications

Affiliations: 
Chemistry Brown University, Providence, RI 
Area:
molecular recognition in biological systems
Website:
http://research.brown.edu/research/profile.php?id=1106970103&r=1
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64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Guo X, Chen Y, Seto CT. Rational design of novel irreversible inhibitors for human arginase. Bioorganic & Medicinal Chemistry. PMID 29914772 DOI: 10.1016/J.Bmc.2018.06.015  0.336
2018 Yu C, Guo X, Shen B, Xi Z, Li Q, Yin Z, Liu H, Muzzio M, Shen M, Li J, Seto CT, Sun S. One-pot formic acid dehydrogenation and synthesis of benzene-fused heterocycles over reusable AgPd/WO2.72 nanocatalyst Journal of Materials Chemistry A. 6: 23766-23772. DOI: 10.1039/C8Ta09342C  0.337
2017 Yu C, Guo X, Xi Z, Muzzio M, Yin Z, Shen B, Li J, Seto C, Sun S. AgPd Nanoparticles Deposited on WO2.72 Nanorods as an Efficient Catalyst for One-Pot Conversion of Nitrophenol/ Nitroacetophenone into Benzoxazole/Quinazoline. Journal of the American Chemical Society. PMID 28402632 DOI: 10.1021/Jacs.7B01983  0.335
2017 Richter N, Dillon JT, Rott DM, Lomazzo MA, Seto CT, Huang Y. Optimizing the yield of transient mono-dimethyl disulfide adducts for elucidating double bond positions of long chain alkenones Organic Geochemistry. 109: 58-66. DOI: 10.1016/J.Orggeochem.2017.02.003  0.309
2011 Xue F, Seto CT. Kinetic delay of cyclization/elimination-coupled enzyme assays: analysis and solution. Bioorganic & Medicinal Chemistry Letters. 21: 1069-71. PMID 21211970 DOI: 10.1016/J.Bmcl.2010.09.104  0.511
2010 Ramroop-Singh N, Narinesingh D, Singh G, Seto CT, Comeau AB. The binding site of zinc and indium metal to amino acid derivatized squarate complexes - Implications in inhibitor and mediator designs. Bioorganic Chemistry. 38: 234-41. PMID 20598337 DOI: 10.1016/J.Bioorg.2010.06.001  0.329
2010 Wang S, Onaran MB, Seto CT. Enantioselective synthesis of 1-aryltetrahydroisoquinolines. Organic Letters. 12: 2690-3. PMID 20481482 DOI: 10.1055/S-0030-1257955  0.543
2010 Xue F, Seto CT. Fluorogenic peptide substrates for serine and threonine phosphatases. Organic Letters. 12: 1936-9. PMID 20359238 DOI: 10.1021/Ol1003065  0.503
2010 FOLKERS JP, ZERKOWSKI JA, LAIBINIS PE, SETO CT, WHITESIDES GM. ChemInform Abstract: Designing Ordered Molecular Arrays in Two and Three Dimensions Cheminform. 24: no-no. DOI: 10.1002/chin.199307312  0.565
2009 Xue F, Seto CT. Macrocyclic inhibitors for the serine protease plasmin. Journal of Enzyme Inhibition and Medicinal Chemistry. 24: 779-94. PMID 18825554 DOI: 10.1080/14756360802364401  0.546
2007 Hassanein M, Xue F, Seto CT, Mason RW. Development of a specific inhibitor for the placental protease, cathepsin P. Archives of Biochemistry and Biophysics. 464: 288-94. PMID 17531191 DOI: 10.1016/J.Abb.2007.04.019  0.514
2007 Xie J, Seto CT. A two stage click-based library of protein tyrosine phosphatase inhibitors. Bioorganic & Medicinal Chemistry. 15: 458-73. PMID 17046267 DOI: 10.1016/J.Bmc.2006.09.036  0.493
2006 Xue F, Seto CT. Structure-activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity. Bioorganic & Medicinal Chemistry. 14: 8467-87. PMID 16971130 DOI: 10.1016/J.Bmc.2006.08.040  0.551
2006 Wang S, Seto CT. Enantioselective addition of vinylzinc reagents to 3,4-dihydroisoquinoline N-oxide. Organic Letters. 8: 3979-82. PMID 16928053 DOI: 10.1021/Ol0614525  0.541
2005 Onaran MB, Comeau AB, Seto CT. Squaric acid-based peptidic inhibitors of matrix metalloprotease-1. The Journal of Organic Chemistry. 70: 10792-802. PMID 16356002 DOI: 10.1021/Jo0517848  0.383
2005 Xue F, Seto CT. Selective inhibitors of the serine protease plasmin: probing the S3 and S3' subsites using a combinatorial library. Journal of Medicinal Chemistry. 48: 6908-17. PMID 16250649 DOI: 10.1021/Jm050488K  0.562
2005 Richmond ML, Sprout CM, Seto CT. Enantioselective addition of vinylzinc reagents to aldehydes catalyzed by modular ligands derived from amino acids. The Journal of Organic Chemistry. 70: 8835-40. PMID 16238316 DOI: 10.1021/Jo051313L  0.763
2005 Sprout CM, Seto CT. Using enzyme inhibition as a high throughput method to measure the enantiomeric excess of a chiral sulfoxide. Organic Letters. 7: 5099-102. PMID 16235967 DOI: 10.1021/Ol0521681  0.762
2005 Xue F, Seto CT. A comparison of cyclohexanone and tetrahydro-4H-thiopyran-4-one 1,1-dioxide as pharmacophores for the design of peptide-based inhibitors of the serine protease plasmin. The Journal of Organic Chemistry. 70: 8309-21. PMID 16209572 DOI: 10.1021/Jo0508954  0.523
2005 Sprout CM, Richmond ML, Seto CT. A positional scanning approach to the discovery of dipeptide-based catalysts for the enantioselective addition of vinylzinc reagents to aldehydes. The Journal of Organic Chemistry. 70: 7408-17. PMID 16122266 DOI: 10.1021/Jo051342W  0.765
2005 Xie J, Seto CT. Investigations of linker structure on the potency of a series of bidentate protein tyrosine phosphatase inhibitors. Bioorganic & Medicinal Chemistry. 13: 2981-91. PMID 15781408 DOI: 10.1016/J.Bmc.2005.02.001  0.498
2004 Sprout CM, Richmond ML, Seto CT. Solid-phase synthesis of chiral N-acylethylenediamines and their use as ligands for the asymmetric addition of alkylzinc and alkenylzinc reagents to aldehydes. The Journal of Organic Chemistry. 69: 6666-73. PMID 15387588 DOI: 10.1021/Jo049160+  0.76
2004 Chen YT, Seto CT. Parallel synthesis of a library of bidentate protein tyrosine phosphatase inhibitors based on the alpha-ketoacid motif. Bioorganic & Medicinal Chemistry. 12: 3289-98. PMID 15158797 DOI: 10.1016/J.Bmc.2004.03.058  0.38
2004 Xie J, Comeau AB, Seto CT. Squaric acids: a new motif for designing inhibitors of protein tyrosine phosphatases. Organic Letters. 6: 83-6. PMID 14703356 DOI: 10.1021/Ol036121W  0.477
2003 Onaran MB, Seto CT. Using a lipase as a high-throughput screening method for measuring the enantiomeric excess of allylic acetates. The Journal of Organic Chemistry. 68: 8136-41. PMID 14535795 DOI: 10.1021/Jo035067U  0.349
2003 Sprout CM, Seto CT. Chiral N-acylethylenediamines as new modular ligands for the catalytic asymmetric addition of alkylzinc reagents to aldehydes. The Journal of Organic Chemistry. 68: 7788-94. PMID 14510556 DOI: 10.1021/Jo0347516  0.788
2003 Richmond ML, Seto CT. Modular ligands derived from amino acids for the enantioselective addition of organozinc reagents to aldehydes. The Journal of Organic Chemistry. 68: 7505-8. PMID 12968907 DOI: 10.1021/Jo0349375  0.75
2003 Chen YT, Xie J, Seto CT. Peptidic alpha-ketocarboxylic acids and sulfonamides as inhibitors of protein tyrosine phosphatases. The Journal of Organic Chemistry. 68: 4123-5. PMID 12737607 DOI: 10.1021/Jo034113N  0.451
2002 Chen YT, Seto CT. Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases. Journal of Medicinal Chemistry. 45: 3946-52. PMID 12190316 DOI: 10.1021/Jm020093Q  0.35
2002 Abato P, Yuen CM, Cubanski JY, Seto CT. Inhibitors of plasmin that extend into both the S and S' binding sites: cooperative interactions between S1 and S2. The Journal of Organic Chemistry. 67: 1184-91. PMID 11846661 DOI: 10.1021/Jo0160569  0.765
2001 Abato P, Seto CT. EMDee: an enzymatic method for determining enantiomeric excess. Journal of the American Chemical Society. 123: 9206-7. PMID 11552847 DOI: 10.1021/Ja016177Q  0.732
2001 Chen YT, Onaran MB, Doss CJ, Seto CT. alpha-Ketocarboxylic acid-based inhibitors of protein tyrosine phosphatases. Bioorganic & Medicinal Chemistry Letters. 11: 1935-8. PMID 11459664 DOI: 10.1016/S0960-894X(01)00325-0  0.321
2000 Ghosh M, Zhang R, Lawler RG, Seto CT. The effects of buffers on the thermodynamics and kinetics of binding between positively-charged cyclodextrins and phosphate ester guests Journal of Organic Chemistry. 65: 735-741. DOI: 10.1021/Jo991616D  0.557
1999 Ghosh M, Conroy JL, Seto CT. Hydrolysis of Amides Catalyzed by 4-Heterocyclohexanones: Small Molecule Mimics of Serine Proteases. Angewandte Chemie (International Ed. in English). 38: 514-516. PMID 29711761 DOI: 10.1002/(Sici)1521-3773(19990215)38:4<514::Aid-Anie514>3.0.Co;2-J  0.586
1999 Ghosh M, Sanders TC, Zhang R, Seto CT. Inhibition of phosphatase activity by positively-charged cyclodextrins. Organic Letters. 1: 1945-8. PMID 10836052 DOI: 10.1021/Ol990301H  0.695
1999 Abato P, Conroy JL, Seto CT. Combinatorial library of serine and cysteine protease inhibitors that interact with both the S and S' binding sites. Journal of Medicinal Chemistry. 42: 4001-9. PMID 10508448 DOI: 10.1021/Jm990272G  0.766
1999 Sanders TC, Seto CT. 4-Heterocyclohexanone-based inhibitors of the serine protease plasmin. Journal of Medicinal Chemistry. 42: 2969-76. PMID 10425106 DOI: 10.1021/Jm990110K  0.58
1999 Ghosh M, Conroy JL, Seto CT. Hydrolysis of amides catalyzed by 4-heterocyclohexanones: Small molecule mimics of serine proteases Angewandte Chemie - International Edition. 38: 514-516. DOI: 10.1002/(SICI)1521-3773(19990215)38:4<514::AID-ANIE514>3.0.CO;2-J  0.513
1999 Ghosh M, Conroy JL, Seto CT. Durch 4-Heterocyclohexanone katalysierte Hydrolyse von Amiden: niedermolekulare Serinprotease-Mimetika Angewandte Chemie. 111: 575-578. DOI: 10.1002/(Sici)1521-3757(19990215)111:4<575::Aid-Ange575>3.0.Co;2-Z  0.492
1998 Conroy JL, Seto CT. Demonstration by 13C NMR studies that tetrahydropyranone-based inhibitors bind to cysteine proteases by reversible formation of a hemithioketal adduct Journal of Organic Chemistry. 63: 2367-2370. DOI: 10.1021/Jo971834B  0.342
1998 Conroy JL, Abato P, Ghosh M, Austermuhle MI, Kiefer MR, Seto CT. Synthesis of cyclohexanone-based cathepsin B inhibitors that interact with both the S and S' binding sites Tetrahedron Letters. 39: 8253-8256. DOI: 10.1016/S0040-4039(98)01783-3  0.76
1997 Conroy JL, Sanders TC, Seto CT. Using the electrostatic field effect to design a new class of inhibitors for cysteine proteases Journal of the American Chemical Society. 119: 4285-4291. DOI: 10.1021/Ja9641867  0.598
1995 Kozlowski MC, Tom NJ, Seto CT, Sefler AM, Bartlett PA. Chorismate-utilizing enzymes isochorismate synthase, Anthranilate synthase, and p-aminobenzoate synthase: Mechanistic insight through inhibitor design Journal of the American Chemical Society. 117: 2128-2140. DOI: 10.1021/Ja00113A002  0.638
1995 Whitesides GM, Simanek EE, Mathias JP, Seto CT, Chin DN, Mammen M, Gordon DM. Noncovalent Synthesis: Using Physical-Organic Chemistry to Make Aggregates Accounts of Chemical Research. 28: 37-44. DOI: 10.1021/Ar00049A006  0.629
1995 Simanek EE, Mammen M, Gordon DM, Chin D, Mathias JP, Seto CT, Whitesides GM. Design and synthesis of hydrogen-bonded aggregates. Theory and computation applied to three systems based on the cyanuric acid-melamine lattice Tetrahedron. 51: 607-619. DOI: 10.1016/0040-4020(94)00920-P  0.616
1994 Seto CT, Bartlett PA. (Z)-9-fluoro-EPSP is not a substrate for EPSP synthase: Implications for the enzyme mechanism Journal of Organic Chemistry. 59: 7130-7132. DOI: 10.1021/Jo00102A046  0.476
1994 Mathias JP, Simanek EE, Zerkowski JA, Seto CT, Whitesides GM. Structural Preferences of Hydrogen-Bonded Networks in Organic Solution - the Cyclic CA3.cntdot.M3 "Rosette" Journal of the American Chemical Society. 116: 4316-4325. DOI: 10.1021/Ja00089A021  0.595
1994 Zerkowski JA, MacDonald JC, Seto CT, Wierda DA, Whitesides GM. Design of Organic Structures in the Solid State: Molecular Tapes Based on the Network of Hydrogen Bonds Present in the Cyanuric Acid.cntdot.Melamine Complex Journal of the American Chemical Society. 116: 2382-2391. DOI: 10.1021/Ja00085A018  0.575
1994 Mathias JP, Seto CT, Simanek EE, Whitesides GM. Self-Assembly through Hydrogen Bonding: Preparation and Characterization of Three New Types of Supramolecular Aggregates Based on Parallel Cyclic CA3.cntdot.M3 "Rosettes" Journal of the American Chemical Society. 116: 1725-1736. DOI: 10.1021/Ja00084A013  0.603
1994 Mathias JP, Simanek EE, Seto CT, Whitesides GM. Design, preparation, and characterization of hydrogen bonded supramolecular aggregates based on the cyanuric acid-melamine lattice Macromolecular Symposia. 77: 157-166. DOI: 10.1002/Masy.19940770119  0.626
1994 Mathias JP, Simanek EE, Zerkowski JA, Seto CT, Whitesides GM. Structural preferences of hydrogen-bonded networks in organic solution - The cyclic CA3·M3 "Rosette" Journal of the American Chemical Society. 116: 4316-4325.  0.563
1994 Zerkowski JA, MacDonald JC, Seto CT, Wierda DA, Whitesides GM. Design of organic structures in the solid state: Molecular tapes based on the network of hydrogen bonds present in the cyanuric acid-melamine complex Journal of the American Chemical Society. 116: 2382-2391.  0.477
1993 Seto CT, Whitesides GM. Synthesis, characterization, and thermodynamic analysis of a 1 + 1 self-assembling structure based on the cyanuric acid.cntdot.melamine lattice Journal of the American Chemical Society. 115: 1330-1340. DOI: 10.1021/Ja00057A016  0.386
1993 Seto CT, Mathias JP, Whitesides GM. Molecular Self-Assembly through Hydrogen Bonding: Aggregation of Five Molecules To Form a Discrete Supramolecular Structure Journal of the American Chemical Society. 115: 1321-1329. DOI: 10.1021/Ja00057A015  0.382
1993 Seto CT, Whitesides GM. Molecular self-assembly through hydrogen bonding: Supramolecular aggregates based on the cyanuric acid-melamine lattice Journal of the American Chemical Society. 115: 905-916. DOI: 10.1021/Ja00056A014  0.385
1993 Mathias JP, Simanek EE, Seto CT, Whitesides GM. Self-assembly through hydrogen bonding: Preparation of a supramolecular aggregate composed of ten molecules Angewandte Chemie (International Edition in English). 32: 1766-1769. DOI: 10.1002/Anie.199317661  0.601
1993 Mathias JP, Simanek EE, Seto CT, Whitesides GM. Selbstorganisation durch Wasserstoffbrücken-bindungen: Herstellung eines supramolekularen Aggregats aus zehn Molekülen Angewandte Chemie. 105: 1848-1850. DOI: 10.1002/Ange.19931051243  0.571
1993 Seto CT, Whitesides GM. Synthesis, characterization, and thermodynamic analysis of a 1 + 1 self-assembling structure based on the cyanuric acid·melamine lattice Journal of the American Chemical Society. 115: 1330-1340.  0.308
1992 Zerkowski JA, Seto CT, Whitesides GM. Solid-state structures of rosette and crinkled tape motifs derived from the cyanuric acid melamine lattice Journal of the American Chemical Society. 114: 5473-5475. DOI: 10.1021/Ja00039A096  0.403
1992 Zerkowski JA, Seto CT, Whitesides GM. Solid-state structures of "rosette" and "crinkled tape" motifs derived from the cyanuric acid-melamine lattice Journal of the American Chemical Society. 114: 5473-5475.  0.312
1991 Whitesides GM, Mathias JP, Seto CT. Molecular self-assembly and nanochemistry: a chemical strategy for the synthesis of nanostructures. Science (New York, N.Y.). 254: 1312-9. PMID 1962191 DOI: 10.1126/Science.1962191  0.414
1991 Seto CT, Whitesides GM. Self-assembly of a hydrogen-bonded 2 + 3 supramolecular complex Journal of the American Chemical Society. 113: 712-713. DOI: 10.1021/Ja00002A071  0.388
1990 Zerkowski JA, Seto CT, Wierda DA, Whitesides GM. Design of organic structures in the solid state: Hydrogen-bonded molecular "tapes" Journal of the American Chemical Society. 112: 9025-9026. DOI: 10.1021/Ja00180A083  0.389
1990 Seto CT, Whitesides GM. Self-assembly based on the cyanuric acid-melamine lattice Journal of the American Chemical Society. 112: 6409-6411. DOI: 10.1021/Ja00173A046  0.383
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