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Dan E. Arking, Ph.D. - Publications

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
Genetics
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146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Young WJ, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody JA, Salman R, Noordam R, Benjamins JW, Haessler J, Lyytikäinen LP, Repetto L, Concas MP, van den Berg ME, ... ... Arking DE, et al. Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature Communications. 13: 5144. PMID 36050321 DOI: 10.1038/s41467-022-32821-z  0.325
2022 Nauffal V, Morrill VN, Jurgens SJ, Choi SH, Hall AW, Weng LC, Halford JL, Austin-Tse C, Haggerty CM, Harris SL, Wong EK, Alonso A, Arking DE, Benjamin EJ, Boerwinkle E, et al. Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation. PMID 35389749 DOI: 10.1161/CIRCULATIONAHA.121.057261  0.339
2021 Choi SH, Jurgens SJ, Haggerty CM, Hall AW, Halford JL, Morrill VN, Weng LC, Lagerman B, Mirshahi T, Pettinger M, Guo X, Lin HJ, Alonso A, Soliman EZ, Kornej J, ... ... Arking DE, et al. Rare Coding Variants Associated with Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-ancestry Analysis. Circulation. Genomic and Precision Medicine. PMID 34319147 DOI: 10.1161/CIRCGEN.120.003300  0.356
2020 Weng LC, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H, Teumer A, Li-Gao R, Yao J, Guo X, Brody JA, Müller-Nurasyid M, Schramm K, ... ... Arking DE, et al. Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation. Circulation. Genomic and Precision Medicine. PMID 32822252 DOI: 10.1161/CIRCGEN.119.002874  0.325
2020 Baldassari AR, Sitlani CM, Highland HM, Arking DE, Buyske S, Darbar D, Gondalia R, Graff M, Guo X, Heckbert SR, Hindorff LA, Hodonsky CJ, Chen YI, Kaplan RC, Peters U, et al. Multi-ethnic Genome-wide Association Study of Decomposed Cardioelectric Phenotypes Illustrates Strategies to Identify and Characterize Evidence of Shared Genetic Effects for Complex Traits. Circulation. Genomic and Precision Medicine. PMID 32602732 DOI: 10.1161/CIRCGEN.119.002680  0.313
2020 Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD, Roselli C, Barnes MR, Mifsud B, Warren HR, Hayward C, Marten J, Cranley JJ, ... ... Arking DE, et al. Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications. 11: 2542. PMID 32439900 DOI: 10.1038/S41467-020-15706-X  0.424
2020 de Las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR, Guo X, Manning A, Chasman DI, Aschard H, Bartz TM, Bielak LF, Campbell A, ... ... Arking DE, et al. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Molecular Psychiatry. PMID 32372009 DOI: 10.1038/S41380-020-0719-3  0.362
2020 Castellani CA, Arking DE. High-Risk, High-Reward Genetics in ASD. Neuron. 105: 407-410. PMID 32027831 DOI: 10.1016/J.Neuron.2020.01.007  0.336
2020 Longchamps RJ, Castellani CA, Yang SY, Newcomb CE, Sumpter JA, Lane J, Grove ML, Guallar E, Pankratz N, Taylor KD, Rotter JI, Boerwinkle E, Arking DE. Evaluation of mitochondrial DNA copy number estimation techniques. Plos One. 15: e0228166. PMID 32004343 DOI: 10.1371/Journal.Pone.0228166  0.332
2020 Jurgens SJ, Choi SH, Haggerty CM, Hall AW, Halford J, Morrill V, Weng LC, Lagerman B, Mirshahi T, Pettinger M, Guo X, Kornej J, Lin H, Moscati A, Nadkarni G, ... ... Arking DE, et al. Abstract 14629: Rare Variants for Electrocardiographic Traits Identify Arrhythmia Susceptibility Genes Circulation. 142. DOI: 10.1161/CIRC.142.SUPPL_3.14629  0.316
2019 Mitchell RN, Ashar FN, Jarvelin MR, Froguel P, Sotoodehnia N, Brody JA, Sebert S, Huikuri H, Rioux J, Goyette P, Newcomb CE, Junttila MJ, Arking DE. Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death. Journal of the American Heart Association. 8: e013751. PMID 31747862 DOI: 10.1161/Jaha.119.013751  0.402
2019 Wang TY, Arking DE, Maleszewski JJ, Fox-Talbot K, Nieuwenhuis TO, Santhanam L, Virmani R, Rosenberg AZ, Halushka MK. Human cardiac myosin light chain 4 (MYL4) mosaic expression patterns vary by sex. Scientific Reports. 9: 12681. PMID 31481666 DOI: 10.1038/S41598-019-49191-0  0.306
2019 Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications. 10: 3669. PMID 31413261 DOI: 10.1038/S41467-019-11558-2  0.401
2019 Vincentz JW, Firulli BA, Toolan KP, Arking DE, Sotoodehnia N, Wan J, Chen PS, de Gier-de Vries C, Christoffels VM, Rubart-von der Lohe M, Firulli AB. Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. Circulation Research. PMID 31366290 DOI: 10.1161/Circresaha.119.315313  0.384
2019 Evangelou E, Gao H, Chu C, Ntritsos G, Blakeley P, Butts AR, Pazoki R, Suzuki H, Koskeridis F, Yiorkas AM, Karaman I, Elliott J, Luo Q, Aeschbacher S, Bartz TM, ... ... Arking DE, et al. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour. PMID 31358974 DOI: 10.1038/S41562-019-0653-Z  0.317
2019 Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, ... ... Arking DE, et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics. PMID 31127295 DOI: 10.1093/Hmg/Ddz070  0.353
2019 Kapoor A, Lee D, Zhu L, Soliman EZ, Grove ML, Boerwinkle E, Arking DE, Chakravarti A. Multiple variant enhancers modulate its cardiac gene expression and the QT interval. Proceedings of the National Academy of Sciences of the United States of America. PMID 31068470 DOI: 10.1073/Pnas.1808734116  0.436
2019 Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, ... ... Arking DE, et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 51: 636-648. PMID 30926973 DOI: 10.1038/S41588-019-0378-Y  0.329
2019 Whitman IR, Vittinghoff E, DeFilippi CR, Gottdiener JS, Alonso A, Psaty BM, Heckbert SR, Hoogeveen RC, Arking DE, Selvin E, Chen LY, Dewland TA, Marcus GM. NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure. Journal of the American Heart Association. 8: e010868. PMID 30912456 DOI: 10.1161/Jaha.118.010868  0.309
2019 de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, ... ... Arking DE, et al. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology. PMID 30698716 DOI: 10.1093/Aje/Kwz005  0.341
2019 van Setten J, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I, Grarup N, Hall LM, Hemerich D, Lyytikäinen LP, Mei H, Müller-Nurasyid M, Prins BP, et al. Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics : Ejhg. PMID 30679814 DOI: 10.1038/S41431-018-0295-Z  0.326
2019 Ellervik C, Roselli C, Christophersen IE, Alonso A, Pietzner M, Sitlani CM, Trompet S, Arking DE, Geelhoed B, Guo X, Kleber ME, Lin HJ, Lin H, MacFarlane P, Selvin E, et al. Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study. Jama Cardiology. PMID 30673084 DOI: 10.1001/Jamacardio.2018.4635  0.34
2019 Petty LE, Highland HM, Gamazon ER, Hu H, Karhade M, Chen HH, de Vries PS, Grove ML, Aguilar D, Bell GI, Huff CD, Hanis CL, Doddapaneni H, Munzy DM, Gibbs RA, ... ... Arking DE, et al. Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample. Human Molecular Genetics. PMID 30624610 DOI: 10.1093/Hmg/Ddy435  0.412
2018 Kraja AT, Liu C, Fetterman JL, Graff M, Have CT, Gu C, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Hill WD, Weiss S, Luan J, et al. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. American Journal of Human Genetics. PMID 30595373 DOI: 10.1016/J.Ajhg.2018.12.001  0.381
2018 Choi SH, Weng LC, Roselli C, Lin H, Haggerty CM, Shoemaker MB, Barnard J, Arking DE, Chasman DI, Albert CM, Chaffin M, Tucker NR, Smith JD, Gupta N, Gabriel S, et al. Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. Jama. 320: 2354-2364. PMID 30535219 DOI: 10.1001/Jama.2018.18179  0.366
2018 Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, ... ... Arking DE, et al. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30429575 DOI: 10.1038/S41588-018-0297-3  0.304
2018 Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, et al. Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nature Communications. 9: 4455. PMID 30367059 DOI: 10.1038/S41467-018-06356-1  0.371
2018 van Setten J, Brody JA, Jamshidi Y, Swenson BR, Butler AM, Campbell H, Del Greco FM, Evans DS, Gibson Q, Gudbjartsson DF, Kerr KF, Krijthe BP, Lyytikäinen LP, Müller C, Müller-Nurasyid M, ... ... Arking DE, et al. PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications. 9: 2904. PMID 30046033 DOI: 10.1038/S41467-018-04766-9  0.312
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, ... ... Arking DE, et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. PMID 29942086 DOI: 10.1038/S41588-018-0152-6  0.427
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Arking D, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.317
2018 Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Bentley AR, ... ... Arking DE, et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Plos One. 13: e0198166. PMID 29912962 DOI: 10.1371/Journal.Pone.0198166  0.356
2018 Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, ... ... Arking DE, et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 9: 2098. PMID 29844566 DOI: 10.1038/S41467-018-04362-X  0.339
2018 Tin A, Nadkarni G, Evans AM, Winkler CA, Bottinger E, Rebholz CM, Sarnak MJ, Inker LA, Levey AS, Lipkowitz MS, Appel LJ, Arking DE, Coresh J, Grams ME. Serum 6-Bromotryptophan Levels Identified as a Risk Factor for CKD Progression. Journal of the American Society of Nephrology : Jasn. PMID 29777021 DOI: 10.1681/Asn.2017101064  0.376
2018 Tereshchenko LG, Sotoodehnia N, Sitlani CM, Ashar FN, Kabir M, Biggs ML, Morley MP, Waks JW, Soliman EZ, Buxton AE, Biering-Sørensen T, Solomon SD, Post WS, Cappola TP, Siscovick DS, ... Arking DE, et al. Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study). Journal of the American Heart Association. 7. PMID 29622589 DOI: 10.1161/Jaha.117.008160  0.4
2018 Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, ... ... Arking D, et al. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. American Journal of Human Genetics. PMID 29455858 DOI: 10.1016/J.Ajhg.2018.01.015  0.409
2018 Vincentz JW, Firulli BA, Toolan KP, Arking DE, Sotoodehnia N, Wan J, Chen P, de Gier-de Vries C, Christoffels VM, Rubart-von der Lohe M, Firulli AB. Abstract 17134: Variation Within a Left Ventricle-Specific Hand1 Enhancer Impairs Gata Transcription Factor Binding and Disrupts Ventricular Conduction System Development Circulation. 138. DOI: 10.1161/circ.138.suppl_1.17134  0.301
2017 Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, ... ... Arking DE, et al. GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Molecular Psychiatry. 22: 1651-1652. PMID 29068436 DOI: 10.1038/Mp.2017.197  0.326
2017 Hatzimanolis A, Avramopoulos D, Arking DE, Moes A, Bhatnagar P, Lencz T, Malhotra AK, Giakoumaki SG, Roussos P, Smyrnis N, Bitsios P, Stefanis NC. Stress-Dependent Association Between Polygenic Risk for Schizophrenia and Schizotypal Traits in Young Army Recruits. Schizophrenia Bulletin. PMID 29036523 DOI: 10.1093/Schbul/Sbx074  0.364
2017 Weng LC, Lunetta KL, Müller-Nurasyid M, Smith AV, Thériault S, Weeke PE, Barnard J, Bis JC, Lyytikäinen LP, Kleber ME, Martinsson A, Lin HJ, Rienstra M, Trompet S, Krijthe BP, ... ... Arking DE, et al. Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium. Scientific Reports. 7: 11303. PMID 28900195 DOI: 10.1038/S41598-017-09396-7  0.385
2017 Christophersen IE, Magnani JW, Yin X, Barnard J, Weng LC, Arking DE, Niemeijer MN, Lubitz SA, Avery CL, Duan Q, Felix SB, Bis JC, Kerr KF, Isaacs A, Müller-Nurasyid M, et al. Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. Circulation. Cardiovascular Genetics. 10. PMID 28794112 DOI: 10.1161/Circgenetics.116.001667  0.301
2017 Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, et al. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension (Dallas, Tex. : 1979). PMID 28739976 DOI: 10.1161/Hypertensionaha.117.09438  0.355
2017 Chaturvedi S, Bhatnagar P, Bean CJ, Steinberg MH, Milton JN, Casella JF, Barron-Casella E, Arking DE, DeBaun MR. Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia. Blood. PMID 28584135 DOI: 10.1182/Blood-2017-02-769661  0.306
2017 Arenas de Larriva AP, Norby FL, Chen LY, Soliman EZ, Hoogeveen RC, Arking DE, Loehr LR, Alonso A. Circulating ceruloplasmin, ceruloplasmin-associated genes, and the incidence of atrial fibrillation in the atherosclerosis risk in communities study. International Journal of Cardiology. PMID 28427851 DOI: 10.1016/J.Ijcard.2017.04.005  0.373
2017 Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, et al. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics. PMID 28416818 DOI: 10.1038/Ng.3843  0.318
2017 Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, ... ... Arking DE, et al. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. Jama Oncology. PMID 28241208 DOI: 10.1001/Jamaoncol.2016.5945  0.306
2017 Soliman EZ, Zhang ZM, Chen LY, Tereshchenko LG, Arking D, Alonso A. Usefulness of Maintaining a Normal Electrocardiogram Over Time for Predicting Cardiovascular Health. The American Journal of Cardiology. 119: 249-255. PMID 28126148 DOI: 10.1016/J.Amjcard.2016.09.051  0.327
2016 Chatterjee NA, Giulianini F, Geelhoed B, Lunetta KL, Misialek JR, Niemeijer MN, Rienstra M, Rose LM, Smith AV, Arking DE, Ellinor PT, Heeringa J, Lin H, Lubitz SA, Soliman EZ, et al. Genetic Obesity and the Risk of Atrial Fibrillation- Causal Estimates from Mendelian Randomization. Circulation. PMID 27974350 DOI: 10.1161/Circulationaha.116.024921  0.327
2016 Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, ... ... Arking DE, et al. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology : Jasn. PMID 27920155 DOI: 10.1681/Asn.2016020131  0.426
2016 Lin H, Mueller-Nurasyid M, Smith AV, Arking DE, Barnard J, Bartz TM, Lunetta KL, Lohman K, Kleber ME, Lubitz SA, Geelhoed B, Trompet S, Niemeijer MN, Kacprowski T, Chasman DI, et al. Gene-gene Interaction Analyses for Atrial Fibrillation. Scientific Reports. 6: 35371. PMID 27824142 DOI: 10.1038/Srep35371  0.374
2016 Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, ... ... Arking DE, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics. PMID 27618452 DOI: 10.1038/Ng.3667  0.339
2016 Lubitz SA, Brody JA, Bihlmeyer NA, Roselli C, Weng LC, Christophersen IE, Alonso A, Boerwinkle E, Gibbs RA, Bis JC, Cupples LA, Mohler PJ, Nickerson DA, Muzny D, ... ... Arking DE, et al. Whole Exome Sequencing in Atrial Fibrillation. Plos Genetics. 12: e1006284. PMID 27589061 DOI: 10.1371/Journal.Pgen.1006284  0.306
2016 Evans DS, Avery CL, Nalls MA, Li G, Barnard J, Smith EN, Tanaka T, Butler AM, Buxbaum SG, Alonso A, Arking DE, Berenson GS, Bis JC, Buyske S, Carty CL, et al. Fine-mapping, Novel Loci Identification, and SNP Association Transferability in a Genome-Wide Association Study of QRS Duration in African Americans. Human Molecular Genetics. PMID 27577874 DOI: 10.1093/Hmg/Ddw284  0.422
2016 Roberts JD, Hu D, Heckbert SR, Alonso A, Dewland TA, Vittinghoff E, Liu Y, Psaty BM, Olgin JE, Magnani JW, Huntsman S, Burchard EG, Arking DE, Bibbins-Domingo K, Harris TB, et al. Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. Jama Cardiology. 1: 442-450. PMID 27438321 DOI: 10.1001/Jamacardio.2016.1185  0.347
2016 Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, ... ... Arking DE, et al. GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Aging Cell. PMID 27325353 DOI: 10.1111/Acel.12468  0.354
2016 Kapoor A, Bakshy K, Xu L, Nandakumar P, Lee D, Boerwinkle E, Grove ML, Arking DE, Chakravarti A. Rare coding TTN variants are associated with electrocardiographic QT interval in the general population. Scientific Reports. 6: 28356. PMID 27321809 DOI: 10.1038/Srep28356  0.422
2016 Ellis SE, Panitch R, West AB, Arking DE. Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia. Translational Psychiatry. 6: e817. PMID 27219343 DOI: 10.1038/Tp.2016.87  0.327
2016 Roberts JD, Dewland TA, Glidden DV, Hoffmann TJ, Arking DE, Chen LY, Psaty BM, Olgin JE, Alonso A, Heckbert SR, Marcus GM. Impact of genetic variants on the upstream efficacy of renin-angiotensin system inhibitors for the prevention of atrial fibrillation. American Heart Journal. 175: 9-17. PMID 27179719 DOI: 10.1016/J.Ahj.2016.02.002  0.365
2016 van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, ... ... Arking DE, et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics. PMID 27036123 DOI: 10.1136/Jmedgenet-2015-103439  0.393
2016 Norby FL, Eryd SA, Niemeijer MN, Rose LM, Smith AV, Yin X, Agarwal SK, Arking DE, Chasman DL, Chen LY, Eijgelsheim M, Engström G, Franco OH, Heeringa J, Hindy G, et al. Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium. Plos One. 11: e0151932. PMID 26999784 DOI: 10.1371/Journal.Pone.0151932  0.354
2016 Verweij N, Mateo Leach I, Isaacs A, Arking DE, Bis JC, Pers TH, van den Berg ME, Lyytikäinen LP, Barnett P, Wang X, Soliman EZ, van Duijn CM, Kähönen M, van Veldhuisen DJ, et al. Twenty-eight genetic loci associated with ST-T wave amplitudes of the electrocardiogram. Human Molecular Genetics. PMID 26962151 DOI: 10.1093/Hmg/Ddw058  0.356
2016 Tin A, Grams ME, Ashar FN, Lane JA, Rosenberg AZ, Grove ML, Boerwinkle E, Selvin E, Coresh J, Pankratz N, Arking DE. Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study. Journal of the American Society of Nephrology : Jasn. PMID 26794963 DOI: 10.1681/Asn.2015060661  0.345
2015 Arking D, Rommens J. Editorial overview: Molecular and genetic bases of disease: Enter the post-GWAS era. Current Opinion in Genetics & Development. 33: 77-79. PMID 26496009 DOI: 10.1016/J.Gde.2015.10.001  0.317
2015 Hatzimanolis A, Bhatnagar P, Moes A, Wang R, Roussos P, Bitsios P, Stefanis CN, Pulver AE, Arking DE, Smyrnis N, Stefanis NC, Avramopoulos D. Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 392-401. PMID 25963331 DOI: 10.1002/Ajmg.B.32323  0.43
2015 Waks JW, Soliman EZ, Henrikson CA, Sotoodehnia N, Han L, Agarwal SK, Arking DE, Siscovick DS, Solomon SD, Post WS, Josephson ME, Coresh J, Tereshchenko LG. Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study. Journal of the American Heart Association. 4: e001357. PMID 25600143 DOI: 10.1161/Jaha.114.001357  0.347
2015 Ashar FN, Moes A, Moore AZ, Grove ML, Chaves PH, Coresh J, Newman AB, Matteini AM, Bandeen-Roche K, Boerwinkle E, Walston JD, Arking DE. Association of mitochondrial DNA levels with frailty and all-cause mortality. Journal of Molecular Medicine (Berlin, Germany). 93: 177-86. PMID 25471480 DOI: 10.1007/S00109-014-1233-3  0.329
2014 Bihlmeyer NA, Brody JA, Smith AV, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza SS, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, ... ... Arking DE, et al. Genetic diversity is a predictor of mortality in humans. Bmc Genetics. 15: 159. PMID 25543667 DOI: 10.1186/S12863-014-0159-7  0.387
2014 Tereshchenko LG, Henrikson CA, Sotoodehnia N, Arking DE, Agarwal SK, Siscovick DS, Post WS, Solomon SD, Coresh J, Josephson ME, Soliman EZ. Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study. Journal of the American Heart Association. 3: e001387. PMID 25416036 DOI: 10.1161/Jaha.114.001387  0.356
2014 Qureshi W, Soliman EZ, Solomon SD, Alonso A, Arking DE, Shah A, Gupta DK, Wagenknecht LE, Herrington D. Risk factors for atrial fibrillation in patients with normal versus dilated left atrium (from the Atherosclerosis Risk in Communities Study). The American Journal of Cardiology. 114: 1368-72. PMID 25245413 DOI: 10.1016/J.Amjcard.2014.07.073  0.325
2014 Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, Teumer A, Winkler TW, TÅ¡ernikova N, Luan J, Mihailov E, Ehret GB, Zhang W, Lamparter D, Esko T, ... ... Arking DE, et al. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. Plos Genetics. 10: e1004508. PMID 25078964 DOI: 10.1371/Journal.Pgen.1004508  0.378
2014 Ilkhanoff L, Arking DE, Lemaitre RN, Alonso A, Chen LY, Durda P, Hesselson SE, Kerr KF, Magnani JW, Marcus GM, Schnabel RB, Smith JG, Soliman EZ, Reiner AP, Sotoodehnia N, et al. A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans. Journal of Cardiovascular Electrophysiology. 25: 1150-7. PMID 25065297 DOI: 10.1111/Jce.12483  0.404
2014 Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics. 46: 826-36. PMID 24952745 DOI: 10.1038/Ng.3014  0.305
2014 Kapoor A, Sekar RB, Hansen NF, Fox-Talbot K, Morley M, Pihur V, Chatterjee S, Brandimarto J, Moravec CS, Pulit SL, Pfeufer A, Mullikin J, Ross M, Green ED, ... ... Arking DE, et al. An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval. American Journal of Human Genetics. 94: 854-69. PMID 24857694 DOI: 10.1016/J.Ajhg.2014.05.001  0.443
2014 Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, et al. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology. 63: 1200-10. PMID 24486271 DOI: 10.1016/J.Jacc.2013.12.015  0.394
2014 Lemaitre RN, Johnson CO, Hesselson S, Sotoodehnia N, Sotoodhenia N, McKnight B, Sitlani CM, Rea TD, King IB, Kwok PY, Mak A, Li G, Brody J, Larson E, Mozaffarian D, ... ... Arking DE, et al. Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 471-7. PMID 24418166 DOI: 10.1016/J.Hrthm.2014.01.008  0.358
2014 Lin H, Sinner MF, Brody JA, Arking DE, Lunetta KL, Rienstra M, Lubitz SA, Magnani JW, Sotoodehnia N, McKnight B, McManus DD, Boerwinkle E, Psaty BM, Rotter JI, Bis JC, et al. Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 452-7. PMID 24239840 DOI: 10.1016/J.Hrthm.2013.11.012  0.445
2014 Matteini AM, Li J, Lange EM, Tanaka T, Lange LA, Tracy RP, Wang Y, Biggs ML, Arking DE, Fallin MD, Chakravarti A, Psaty BM, Bandinelli S, Ferrucci L, Reiner AP, et al. Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults. Cytokine. 65: 10-6. PMID 24182552 DOI: 10.1016/J.Cyto.2013.10.002  0.315
2014 Avery CL, Sitlani CM, Arking DE, Arnett DK, Bis JC, Boerwinkle E, Buckley BM, Ida Chen YD, de Craen AJ, Eijgelsheim M, Enquobahrie D, Evans DS, Ford I, Garcia ME, Gudnason V, et al. Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. The Pharmacogenomics Journal. 14: 6-13. PMID 23459443 DOI: 10.1038/Tpj.2013.4  0.316
2013 Sampath S, Bhat S, Gupta S, O'Connor A, West AB, Arking DE, Chakravarti A. Defining the contribution of CNTNAP2 to autism susceptibility. Plos One. 8: e77906. PMID 24147096 DOI: 10.1371/Journal.Pone.0077906  0.372
2013 Abrahams BS, Arking DE, Campbell DB, Mefford HC, Morrow EM, Weiss LA, Menashe I, Wadkins T, Banerjee-Basu S, Packer A. SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs). Molecular Autism. 4: 36. PMID 24090431 DOI: 10.1186/2040-2392-4-36  0.322
2013 O'Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, Köttgen A, Stoudmann C, Teumer A, Kutalik Z, Mangino M, Dehghan A, Zhang W, Eiriksdottir G, Li G, ... ... Arking DE, et al. Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. Plos Genetics. 9: e1003796. PMID 24068962 DOI: 10.1371/Journal.Pgen.1003796  0.374
2013 Bhatnagar P, Barron-Casella E, Bean CJ, Milton JN, Baldwin CT, Steinberg MH, Debaun M, Casella JF, Arking DE. Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. Plos One. 8: e74193. PMID 24058526 DOI: 10.1371/Journal.Pone.0074193  0.454
2013 Chanda P, Huang H, Arking DE, Bader JS. Fast association tests for genes with FAST. Plos One. 8: e68585. PMID 23935874 DOI: 10.1371/Journal.Pone.0068585  0.366
2013 Talebizadeh Z, Arking DE, Hu VW. A Novel Stratification Method in Linkage Studies to Address Inter- and Intra-Family Heterogeneity in Autism. Plos One. 8: e67569. PMID 23840741 DOI: 10.1371/Journal.Pone.0067569  0.353
2013 den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, ... ... Arking DE, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 45: 621-31. PMID 23583979 DOI: 10.1038/Ng.2610  0.374
2013 Deo R, Nalls MA, Avery CL, Smith JG, Evans DS, Keller MF, Butler AM, Buxbaum SG, Li G, Miguel Quibrera P, Smith EN, Tanaka T, Akylbekova EL, Alonso A, Arking DE, et al. Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 401-8. PMID 23183192 DOI: 10.1016/J.Hrthm.2012.11.014  0.442
2012 Smith JG, Avery CL, Evans DS, Nalls MA, Meng YA, Smith EN, Palmer C, Tanaka T, Mehra R, Butler AM, Young T, Buxbaum SG, Kerr KF, Berenson GS, Schnabel RB, ... ... Arking DE, et al. Impact of ancestry and common genetic variants on QT interval in African Americans. Circulation. Cardiovascular Genetics. 5: 647-55. PMID 23166209 DOI: 10.1161/Circgenetics.112.962787  0.457
2012 Butler AM, Yin X, Evans DS, Nalls MA, Smith EN, Tanaka T, Li G, Buxbaum SG, Whitsel EA, Alonso A, Arking DE, Benjamin EJ, Berenson GS, Bis JC, Chen W, et al. Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. Circulation. Cardiovascular Genetics. 5: 639-46. PMID 23139255 DOI: 10.1161/Circgenetics.112.963991  0.435
2012 Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, et al. Fine-mapping and initial characterization of QT interval loci in African Americans. Plos Genetics. 8: e1002870. PMID 22912591 DOI: 10.1371/Journal.Pgen.1002870  0.415
2012 Bhatnagar P, Lu X, Evans MK, Laveist TA, Zonderman AB, Carter DL, Arking DE, Fletcher CA. Genetic variants in platelet factor 4 modulate inflammatory and platelet activation biomarkers. Circulation. Cardiovascular Genetics. 5: 412-21. PMID 22763266 DOI: 10.1161/Circgenetics.111.961813  0.349
2012 Arking DE, Sotoodehnia N. The genetics of sudden cardiac death. Annual Review of Genomics and Human Genetics. 13: 223-39. PMID 22703174 DOI: 10.1146/Annurev-Genom-090711-163841  0.398
2012 Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/Journal.Pgen.1002741  0.302
2012 Chanda P, Yuhki N, Li M, Bader JS, Hartz A, Boerwinkle E, Kao WH, Arking DE. Comprehensive evaluation of imputation performance in African Americans. Journal of Human Genetics. 57: 411-21. PMID 22648186 DOI: 10.1038/Jhg.2012.43  0.363
2012 Milton JN, Sebastiani P, Solovieff N, Hartley SW, Bhatnagar P, Arking DE, Dworkis DA, Casella JF, Barron-Casella E, Bean CJ, Hooper WC, DeBaun MR, Garrett ME, Soldano K, Telen MJ, et al. A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. Plos One. 7: e34741. PMID 22558097 DOI: 10.1371/Journal.Pone.0034741  0.415
2012 Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Müller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dörr M, Ozaki K, Roberts JD, et al. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nature Genetics. 44: 670-5. PMID 22544366 DOI: 10.1038/Ng.2261  0.383
2012 Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tönjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, ... ... Arking DE, et al. No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes. 61: 1291-6. PMID 22415877 DOI: 10.2337/Db11-0973  0.335
2012 Gupta S, Halushka MK, Hilton GM, Arking DE. Postmortem cardiac tissue maintains gene expression profile even after late harvesting. Bmc Genomics. 13: 26. PMID 22251372 DOI: 10.1186/1471-2164-13-26  0.32
2011 Benke KS, Carlson MC, Doan BQ, Walston JD, Xue QL, Reiner AP, Fried LP, Arking DE, Chakravarti A, Fallin MD. The association of genetic variants in interleukin-1 genes with cognition: findings from the cardiovascular health study. Experimental Gerontology. 46: 1010-9. PMID 21968104 DOI: 10.1016/J.Exger.2011.09.005  0.383
2011 Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, ... ... Arking DE, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 478: 103-9. PMID 21909115 DOI: 10.1038/Nature10405  0.329
2011 Schnabel RB, Kerr KF, Lubitz SA, Alkylbekova EL, Marcus GM, Sinner MF, Magnani JW, Wolf PA, Deo R, Lloyd-Jones DM, Lunetta KL, Mehra R, Levy D, Fox ER, Arking DE, et al. Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project. Circulation. Cardiovascular Genetics. 4: 557-64. PMID 21846873 DOI: 10.1161/Circgenetics.110.959197  0.414
2011 Huang H, Chanda P, Alonso A, Bader JS, Arking DE. Gene-based tests of association. Plos Genetics. 7: e1002177. PMID 21829371 DOI: 10.1371/Journal.Pgen.1002177  0.429
2011 Ho YY, Matteini AM, Beamer B, Fried L, Xue QL, Arking DE, Chakravarti A, Fallin MD, Walston J. Exploring biologically relevant pathways in frailty. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 66: 975-9. PMID 21743092 DOI: 10.1093/Gerona/Glr061  0.404
2011 Arking DE, Junttila MJ, Goyette P, Huertas-Vazquez A, Eijgelsheim M, Blom MT, Newton-Cheh C, Reinier K, Teodorescu C, Uy-Evanado A, Carter-Monroe N, Kaikkonen KS, Kortelainen ML, Boucher G, Lagacé C, et al. Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals. Plos Genetics. 7: e1002158. PMID 21738491 DOI: 10.1371/Journal.Pgen.1002158  0.437
2011 Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, ... ... Arking DE, et al. CUBN is a gene locus for albuminuria. Journal of the American Society of Nephrology : Jasn. 22: 555-70. PMID 21355061 DOI: 10.1681/Asn.2010060598  0.411
2011 Bhatnagar P, Purvis S, Barron-Casella E, DeBaun MR, Casella JF, Arking DE, Keefer JR. Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients. Journal of Human Genetics. 56: 316-23. PMID 21326311 DOI: 10.1038/Jhg.2011.12  0.391
2011 Wirka RC, Gore S, Van Wagoner DR, Arking DE, Lubitz SA, Lunetta KL, Benjamin EJ, Alonso A, Ellinor PT, Barnard J, Chung MK, Smith JD. A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation. Circulation. Arrhythmia and Electrophysiology. 4: 87-93. PMID 21076161 DOI: 10.1161/Circep.110.959726  0.384
2010 Sotoodehnia N, Isaacs A, de Bakker PI, Dörr M, Newton-Cheh C, Nolte IM, van der Harst P, Müller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, ... ... Arking DE, et al. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nature Genetics. 42: 1068-76. PMID 21076409 DOI: 10.1038/Ng.716  0.403
2010 Yang Q, Köttgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, et al. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circulation. Cardiovascular Genetics. 3: 523-30. PMID 20884846 DOI: 10.1161/Circgenetics.109.934455  0.387
2010 Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, ... ... Arking D, et al. Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes. 59: 3229-39. PMID 20858683 DOI: 10.2337/Db10-0502  0.388
2010 Fradin D, Cheslack-Postava K, Ladd-Acosta C, Newschaffer C, Chakravarti A, Arking DE, Feinberg A, Fallin MD. Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs. Plos One. 5. PMID 20824079 DOI: 10.1371/Journal.Pone.0012513  0.381
2010 Lubitz SA, Sinner MF, Lunetta KL, Makino S, Pfeufer A, Rahman R, Veltman CE, Barnard J, Bis JC, Danik SP, Sonni A, Shea MA, Del Monte F, Perz S, Müller M, ... ... Arking DE, et al. Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation. 122: 976-84. PMID 20733104 DOI: 10.1161/Circulationaha.109.886440  0.312
2010 Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, de Bakker PI, Müller M, Morrison AC, Smith AV, Isaacs A, Sanna S, Dörr M, Navarro P, Fuchsberger C, Nolte IM, de Geus EJ, Estrada K, ... ... Arking DE, et al. Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics. 19: 3885-94. PMID 20639392 DOI: 10.1093/Hmg/Ddq303  0.4
2010 Tomás M, Napolitano C, De Giuli L, Bloise R, Subirana I, Malovini A, Bellazzi R, Arking DE, Marban E, Chakravarti A, Spooner PM, Priori SG. Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome. Journal of the American College of Cardiology. 55: 2745-52. PMID 20538168 DOI: 10.1016/J.Jacc.2009.12.065  0.419
2010 Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, ... ... Arking DE, et al. New loci associated with kidney function and chronic kidney disease. Nature Genetics. 42: 376-84. PMID 20383146 DOI: 10.1038/Ng.568  0.343
2010 Arking DE, Reinier K, Post W, Jui J, Hilton G, O'Connor A, Prineas RJ, Boerwinkle E, Psaty BM, Tomaselli GF, Rea T, Sotoodehnia N, Siscovick DS, Burke GL, Marban E, et al. Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest. Plos One. 5: e9879. PMID 20360844 DOI: 10.1371/Journal.Pone.0009879  0.46
2010 Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, ... ... Arking DE, et al. Common variants in KCNN3 are associated with lone atrial fibrillation. Nature Genetics. 42: 240-4. PMID 20173747 DOI: 10.1038/Ng.537  0.417
2010 Matteini AM, Walston JD, Bandeen-Roche K, Arking DE, Allen RH, Fried LP, Chakravarti A, Stabler SP, Fallin MD. Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty. The Journal of Nutrition, Health & Aging. 14: 73-7. PMID 20082058 DOI: 10.1007/S12603-010-0013-1  0.307
2010 Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, et al. Genome-wide association study of PR interval. Nature Genetics. 42: 153-9. PMID 20062060 DOI: 10.1038/Ng.517  0.419
2010 Chu AY, Coresh J, Arking DE, Pankow JS, Tomaselli GF, Chakravarti A, Post WS, Spooner PH, Boerwinkle E, Kao WHL. NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study Diabetologia. 53: 510-516. PMID 19943157 DOI: 10.1007/S00125-009-1608-0  0.325
2010 Tanaka T, Roy CN, Yao W, Matteini A, Semba RD, Arking D, Walston JD, Fried LP, Singleton A, Guralnik J, Abecasis GR, Bandinelli S, Longo DL, Ferrucci L. A genome-wide association analysis of serum iron concentrations. Blood. 115: 94-6. PMID 19880490 DOI: 10.1182/Blood-2009-07-232496  0.353
2009 Weiss LA, Arking DE, Daly MJ, Chakravarti A, Brune CW, West K, O'Connor A, Hilton G, Tomlinson RL, West AB, Cook EH, Green T, Chang SC, Gabriel S, Gates C, et al. A genome-wide linkage and association scan reveals novel loci for autism Nature. 461: 802-808. PMID 19812673 DOI: 10.1038/Nature08490  0.438
2009 Arking DE, Chakravarti A. Understanding cardiovascular disease through the lens of genome-wide association studies. Trends in Genetics : Tig. 25: 387-94. PMID 19716196 DOI: 10.1016/J.Tig.2009.07.007  0.412
2009 Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, Arking DE, Amsterdam AH, Sabeh KM, Mably JD, Rosenbaum DS, Peterson RT, Chakravarti A, Kääb S, Roden DM, et al. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation. 120: 553-9. PMID 19652097 DOI: 10.1161/Circulationaha.108.821082  0.39
2009 Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB, Lumley T, Ehret GB, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nature Genetics. 41: 879-81. PMID 19597492 DOI: 10.1038/Ng.416  0.375
2009 Nolte IM, Wallace C, Newhouse SJ, Waggott D, Fu J, Soranzo N, Gwilliam R, Deloukas P, Savelieva I, Zheng D, Dalageorgou C, Farrall M, Samani NJ, Connell J, Brown M, ... ... Arking DE, et al. Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. Plos One. 4: e6138. PMID 19587794 DOI: 10.1371/Journal.Pone.0006138  0.456
2009 SanGiovanni JP, Arking DE, Iyengar SK, Elashoff M, Clemons TE, Reed GF, Henning AK, Sivakumaran TA, Xu X, DeWan A, Agrón E, Rochtchina E, Sue CM, Wang JJ, Mitchell P, et al. Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. Plos One. 4: e5508. PMID 19434233 DOI: 10.1371/Journal.Pone.0005508  0.312
2009 Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nature Genetics. 41: 712-7. PMID 19430482 DOI: 10.1038/Ng.377  0.352
2009 Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, ... ... Arking DE, et al. Genome-wide association study of blood pressure and hypertension. Nature Genetics. 41: 677-87. PMID 19430479 DOI: 10.1038/Ng.384  0.349
2009 Pfeufer A, Sanna S, Arking DE, Müller M, Gateva V, Fuchsberger C, Ehret GB, Orrú M, Pattaro C, Köttgen A, Perz S, Usala G, Barbalic M, Li M, Pütz B, et al. Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nature Genetics. 41: 407-14. PMID 19305409 DOI: 10.1038/Ng.362  0.409
2009 Kao WH, Arking DE, Post W, Rea TD, Sotoodehnia N, Prineas RJ, Bishe B, Doan BQ, Boerwinkle E, Psaty BM, Tomaselli GF, Coresh J, Siscovick DS, Marbán E, Spooner PM, et al. Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations. Circulation. 119: 940-51. PMID 19204306 DOI: 10.1161/Circulationaha.108.791723  0.411
2009 Arking DE, Khera A, Xing C, Kao WH, Post W, Boerwinkle E, Chakravarti A. Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population. Plos One. 4: e4333. PMID 19180230 DOI: 10.1371/Journal.Pone.0004333  0.434
2009 Bhatnagar P, Casella EB, Arking DE, Casella JF. Genome-Wide Association for Silent Cerebral Infarction (SCI) in Sickle Cell Disease: The Silent Infarct Transfusion Trial (SIT) Cohort. Blood. 114: 2563-2563. DOI: 10.1182/Blood.V114.22.2563.2563  0.435
2008 Garringer HJ, Malekpour M, Esteghamat F, Mortazavi SM, Davis SI, Farrow EG, Yu X, Arking DE, Dietz HC, White KE. Molecular genetic and biochemical analyses of FGF23 mutations in familial tumoral calcinosis. American Journal of Physiology. Endocrinology and Metabolism. 295: E929-37. PMID 18682534 DOI: 10.1152/Ajpendo.90456.2008  0.472
2008 Feder J, Blech I, Ovadia O, Amar S, Wainstein J, Raz I, Dadon S, Arking DE, Glaser B, Mishmar D. Differences in mtDNA haplogroup distribution among 3 Jewish populations alter susceptibility to T2DM complications Bmc Genomics. 9. PMID 18445251 DOI: 10.1186/1471-2164-9-198  0.362
2008 Weiss LA, Shen Y, Korn JM, Arking DE, Miller DT, Fossdal R, Saemundsen E, Stefansson H, Ferreira MA, Green T, Platt OS, Ruderfer DM, Walsh CA, Altshuler D, Chakravarti A, et al. Association between microdeletion and microduplication at 16p11.2 and autism. The New England Journal of Medicine. 358: 667-75. PMID 18184952 DOI: 10.1056/Nejmoa075974  0.323
2008 Arking DE, Cutler DJ, Brune CW, Teslovich TM, West K, Ikeda M, Rea A, Guy M, Lin S, Cook EH, Chakravarti A. A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism. American Journal of Human Genetics. 82: 160-4. PMID 18179894 DOI: 10.1016/J.Ajhg.2007.09.015  0.42
2007 Post W, Shen H, Damcott C, Arking DE, Kao WHL, Sack PA, Ryan KA, Chakravarti A, Mitchell BD, Shuldiner AR. Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the Old Order Amish Human Heredity. 64: 214-219. PMID 17565224 DOI: 10.1159/000103630  0.427
2006 Calhoun ES, Hucl T, Gallmeier E, West KM, Arking DE, Maitra A, Iacobuzio-Donahue CA, Chakravarti A, Hruban RH, Kern SE. Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays. Cancer Research. 66: 7920-8. PMID 16912165 DOI: 10.1158/0008-5472.Can-06-0721  0.339
2006 Naghavi M, Falk E, Hecht HS, Jamieson MJ, Kaul S, Berman D, Fayad Z, Budoff MJ, Rumberger J, Naqvi TZ, Shaw LJ, Faergeman O, Cohn J, Bahr R, Koenig W, ... ... Arking D, et al. From vulnerable plaque to vulnerable patient--Part III: Executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report. The American Journal of Cardiology. 98: 2H-15H. PMID 16843744 DOI: 10.1016/J.Amjcard.2006.03.002  0.302
2006 Arking DE, Fallin DM, Fried LP, Li T, Beamer BA, Xue QL, Chakravarti A, Walston J. Variation in the ciliary neurotrophic factor gene and muscle strength in older Caucasian women. Journal of the American Geriatrics Society. 54: 823-6. PMID 16696750 DOI: 10.1111/J.1532-5415.2006.00693.X  0.394
2006 Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, et al. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nature Genetics. 38: 644-51. PMID 16648850 DOI: 10.1038/Ng1790  0.403
2005 Maitra A, Arking DE, Shivapurkar N, Ikeda M, Stastny V, Kassauei K, Sui G, Cutler DJ, Liu Y, Brimble SN, Noaksson K, Hyllner J, Schulz TC, Zeng X, Freed WJ, et al. Genomic alterations in cultured human embryonic stem cells. Nature Genetics. 37: 1099-103. PMID 16142235 DOI: 10.1038/Ng1631  0.304
2005 Arking DE, Atzmon G, Arking A, Barzilai N, Dietz HC. Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity. Circulation Research. 96: 412-8. PMID 15677572 DOI: 10.1161/01.Res.0000157171.04054.30  0.568
2004 Arking DE, Chugh SS, Chakravarti A, Spooner PM. Genomics in sudden cardiac death. Circulation Research. 94: 712-23. PMID 15059941 DOI: 10.1161/01.Res.0000123861.16082.95  0.386
2003 Arking DE, Becker DM, Yanek LR, Fallin D, Judge DP, Moy TF, Becker LC, Dietz HC. KLOTHO allele status and the risk of early-onset occult coronary artery disease. American Journal of Human Genetics. 72: 1154-61. PMID 12669274 DOI: 10.1086/375035  0.551
2003 Neptune ER, Frischmeyer PA, Arking DE, Myers L, Bunton TE, Gayraud B, Ramirez F, Sakai LY, Dietz HC. Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nature Genetics. 33: 407-11. PMID 12598898 DOI: 10.1038/Ng1116  0.696
2002 Arking DE, Krebsova A, Macek M, Macek M, Arking A, Mian IS, Fried L, Hamosh A, Dey S, McIntosh I, Dietz HC. Association of human aging with a functional variant of klotho. Proceedings of the National Academy of Sciences of the United States of America. 99: 856-61. PMID 11792841 DOI: 10.1073/Pnas.022484299  0.584
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