| Year |
Citation |
Score |
| 2020 |
Yang L, Slone J, Zou W, Queme LF, Jankowski MP, Yin F, Huang T. Systemic Delivery of AAV- Mitigates the Phenotypes of Mitochondrial Disorders in Mutant Mice. Molecular Therapy. Methods & Clinical Development. 18: 84-97. PMID 32995353 DOI: 10.1016/J.Omtm.2020.05.021 |
0.365 |
|
| 2020 |
Yu J, Liang X, Ji Y, Ai C, Liu J, Zhu L, Nie Z, Jin X, Wang C, Zhang J, Zhao F, Mei S, Zhao X, Zhou X, Zhang M, ... ... Huang T, et al. PRICKLE3 linked to ATPase biogenesis manifested Leber's hereditary optic neuropathy. The Journal of Clinical Investigation. PMID 32516135 DOI: 10.1172/Jci134965 |
0.458 |
|
| 2020 |
Slone JD, Yang L, Peng Y, Queme LF, Harris B, Rizzo SJS, Green T, Ryan JL, Jankowski MP, Reinholdt LG, Huang T. Integrated analysis of the molecular pathogenesis of FDXR-associated disease. Cell Death & Disease. 11: 423. PMID 32499495 DOI: 10.1038/S41419-020-2637-3 |
0.358 |
|
| 2020 |
Li H, Slone J, Huang T. The Role of Mitochondrial-related Nuclear Genes in Age-related Common Disease. Mitochondrion. PMID 32361035 DOI: 10.1016/J.Mito.2020.04.012 |
0.367 |
|
| 2020 |
Slone J, Huang T. The special considerations of gene therapy for mitochondrial diseases. Npj Genomic Medicine. 5: 7. PMID 32140258 DOI: 10.1038/S41525-020-0116-5 |
0.338 |
|
| 2020 |
Yang L, Slone J, Li Z, Lou X, Hu YC, Queme LF, Jankowski MP, Huang T. Systemic administration of AAV-Slc25a46 mitigates mitochondrial neuropathy in Slc25a46-/- mice. Human Molecular Genetics. PMID 31943007 DOI: 10.1093/Hmg/Ddz277 |
0.36 |
|
| 2019 |
Zou W, Slone J, Cao Y, Huang T. Mitochondria and Their Role in Human Reproduction. Dna and Cell Biology. PMID 31603716 DOI: 10.1089/Dna.2019.4807 |
0.357 |
|
| 2019 |
Li H, Slone J, Fei L, Huang T. Mitochondrial DNA Variants and Common Diseases: A Mathematical Model for the Diversity of Age-Related mtDNA Mutations. Cells. 8. PMID 31216686 DOI: 10.3390/Cells8060608 |
0.413 |
|
| 2019 |
Kang E, Wu J, Gutierrez NM, Koski A, Tippner-Hedges R, Agaronyan K, Platero-Luengo A, Martinez-Redondo P, Ma H, Lee Y, Hayama T, Van Dyken C, Wang X, Luo S, Ahmed R, ... ... Huang T, et al. Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations. Nature. PMID 30814738 DOI: 10.1038/S41586-019-0876-1 |
0.335 |
|
| 2018 |
Ji Y, Zhang J, Yu J, Wang Y, Lu Y, Liang M, Li Q, Jin X, Wei Y, Meng F, Gao Y, Cang X, Tong Y, Liu X, Zhang M, ... ... Huang T, et al. Contribution of mitochondrial ND1 3394T>C mutation to the phenotypic manifestation of Leber's hereditary optic neuropathy. Human Molecular Genetics. PMID 30597069 DOI: 10.1093/Hmg/Ddy450 |
0.391 |
|
| 2018 |
Luo S, Valencia CA, Zhang J, Lee NC, Slone J, Gui B, Wang X, Li Z, Dell S, Brown J, Chen SM, Chien YH, Hwu WL, Fan PC, Wong LJ, ... ... Huang T, et al. Biparental Inheritance of Mitochondrial DNA in Humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 30478036 DOI: 10.1073/Pnas.1810946115 |
0.324 |
|
| 2018 |
Slone J, Peng Y, Chamberlin A, Harris B, Kaylor J, McDonald MT, Lemmon M, El-Dairi MA, Tchapyjnikov D, Gonzalez-Krellwitz LA, Sellars EA, McConkie-Rosell A, Reinholdt LG, Huang T. Biallelic mutations in FDXR cause neurodegeneration associated with inflammation. Journal of Human Genetics. PMID 30250212 DOI: 10.1038/S10038-018-0515-Y |
0.312 |
|
| 2018 |
Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, ... ... Huang T, et al. Pathobiologic Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes. Cancer Discovery. PMID 30139811 DOI: 10.1158/2159-8290.Cd-17-1203 |
0.391 |
|
| 2018 |
Tan ZY, Huang T, Ngeow J. 65 YEARS OF THE DOUBLE HELIX: The advancements of gene editing and potential application to hereditary cancer. Endocrine-Related Cancer. 25: T141-T158. PMID 29980644 DOI: 10.1530/ERC-18-0039 |
0.317 |
|
| 2018 |
Slone J, Gui B, Huang T. The current landscape for the treatment of mitochondrial disorders. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 29502956 DOI: 10.1016/J.Jgg.2017.11.008 |
0.318 |
|
| 2017 |
Gui B, Slone J, Huang T. Perspective: Is Random Monoallelic Expression a Contributor to Phenotypic Variability of Autosomal Dominant Disorders? Frontiers in Genetics. 8: 191. PMID 29250101 DOI: 10.3389/Fgene.2017.00191 |
0.431 |
|
| 2017 |
Peng Y, Shinde DN, Valencia AC, Mo JS, Rosenfeld J, Truitt Cho M, Chamberlin A, Li Z, Liu J, Gui B, Brockhage R, Basinger A, Alvarez-Leon B, Heydemann P, Magoulas PL, ... ... Huang T, et al. Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy. Human Molecular Genetics. PMID 29040572 DOI: 10.1093/Hmg/Ddx377 |
0.417 |
|
| 2017 |
Li Z, Peng Y, Hufnagel RB, Hu YC, Zhao C, Queme LF, Khuchua Z, Driver AM, Dong F, Lu QR, Lindquist DM, Jankowski MP, Stottmann RW, Kao WWY, Huang T. Loss of SLC25A46 causes neurodegeneration by affecting mitochondrial dynamics and energy production in mice. Human Molecular Genetics. 26: 3776-3791. PMID 28934388 DOI: 10.1093/Hmg/Ddx262 |
0.361 |
|
| 2017 |
Zhang J, Liu H, Luo S, Lu Z, Chávez-Badiola A, Liu Z, Yang M, Merhi Z, Silber SJ, Munné S, Konstandinidis M, Wells D, Huang T. Live birth derived from oocyte spindle transfer to prevent mitochondrial disease. Reproductive Biomedicine Online. 34: 361-368. PMID 28385334 DOI: 10.1097/01.Ogx.0000524508.40309.08 |
0.402 |
|
| 2016 |
Kang E, Wu J, Gutierrez NM, Koski A, Tippner-Hedges R, Agaronyan K, Platero-Luengo A, Martinez-Redondo P, Ma H, Lee Y, Hayama T, Van Dyken C, Wang X, Luo S, Ahmed R, ... ... Huang T, et al. Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations. Nature. PMID 27919073 DOI: 10.1038/Nature20592 |
0.434 |
|
| 2016 |
Wang M, Peng Y, Zheng J, Zheng B, Jin X, Liu H, Wang Y, Tang X, Huang T, Jiang P, Guan MX. A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function. Nucleic Acids Research. PMID 27536005 DOI: 10.1093/Nar/Gkw726 |
0.377 |
|
| 2016 |
Jiang P, Liang M, Zhang C, Zhao X, He Q, Cui L, Liu X, Sun YH, Fu Q, Ji Y, Bai Y, Huang T, Guan MX. Biochemical evidence for a mitochondrial genetic modifier in the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation. Human Molecular Genetics. PMID 27427386 DOI: 10.1093/Hmg/Ddw199 |
0.39 |
|
| 2016 |
Twigg SR, Hufnagel RB, Miller KA, Zhou Y, McGowan SJ, Taylor J, Craft J, Taylor JC, Santoro SL, Huang T, Hopkin RJ, Brady AF, Clayton-Smith J, Clericuzio CL, Grange DK, et al. A Recurrent Mosaic Mutation in SMO, Encoding the Hedgehog Signal Transducer Smoothened, Is the Major Cause of Curry-Jones Syndrome. American Journal of Human Genetics. PMID 27236920 DOI: 10.1016/J.Ajhg.2016.04.007 |
0.428 |
|
| 2016 |
Kang E, Wang X, Tippner-Hedges R, Ma H, Folmes CD, Gutierrez NM, Lee Y, Van Dyken C, Ahmed R, Li Y, Koski A, Hayama T, Luo S, Harding CO, Amato P, ... ... Huang T, et al. Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs. Cell Stem Cell. 18: 625-636. PMID 27151456 DOI: 10.1016/J.Stem.2016.02.005 |
0.422 |
|
| 2016 |
Tang ZH, Chen JR, Zheng J, Shi HS, Ding J, Qian XD, Zhang C, Chen JL, Wang CC, Li L, Chen JZ, Yin SK, Huang TS, Chen P, Guan MX, et al. Genetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells. Stem Cells Translational Medicine. PMID 27013738 DOI: 10.5966/Sctm.2015-0252 |
0.411 |
|
| 2016 |
Leslie N, Wang X, Peng Y, Valencia CA, Khuchua Z, Hata J, Witte D, Huang T, Bove KE. Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules. Human Pathology. 49: 27-32. PMID 26826406 DOI: 10.1016/J.Humpath.2015.09.039 |
0.408 |
|
| 2016 |
Chen J, Riazifar H, Guan MX, Huang T. Modeling autosomal dominant optic atrophy using induced pluripotent stem cells and identifying potential therapeutic targets. Stem Cell Research & Therapy. 7: 2. PMID 26738566 DOI: 10.1016/J.Mito.2015.07.086 |
0.329 |
|
| 2016 |
Liu Z, Liu H, Lu Z, Luo S, Chávez AB, Yang M, Merhi Z, Silber S, Munne S, Konstantinidis M, Wells D, Huang T, Zhang J. Prevention of Mitochondrial Disease Caused by mtDNA Mutation through Mitochondrial Replacement Therapy (MRT) Journal of World Mitochondria Society. 2. DOI: 10.18143/Jwms_V2I2_1971 |
0.412 |
|
| 2016 |
Zhang J, Liu H, Luo S, Chavez-Badiola A, Liu Z, yang m, Munne S, Konstantinidis M, Wells D, Huang T. First live birth using human oocytes reconstituted by spindle nuclear transfer for mitochondrial DNA mutation causing Leigh syndrome Fertility and Sterility. 106: e375-e376. DOI: 10.1016/J.Fertnstert.2016.08.004 |
0.403 |
|
| 2016 |
Liu H, Lu Z, Luo S, Chavez-Badiola A, Blazek J, Munne S, Huang T, Zhang J. In vitro fertilization and development of human oocytes reconstituted by spindle nuclear transfer to replace mutated mitochondrial DNA Fertility and Sterility. 106: e21. DOI: 10.1016/J.Fertnstert.2016.07.071 |
0.373 |
|
| 2015 |
Jiang P, Jin X, Peng Y, Wang M, Liu H, Liu X, Zhang Z, Ji Y, Zhang J, Liang M, Zhao F, Sun YH, Zhang M, Zhou X, Chen Y, ... ... Huang T, et al. The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation. Human Molecular Genetics. PMID 26647310 DOI: 10.1093/Hmg/Ddv498 |
0.436 |
|
| 2015 |
Jiang P, Liang M, Zhang J, Gao Y, He Z, Yu H, Zhao F, Ji Y, Liu X, Zhang M, Fu Q, Tong Y, Sun Y, Zhou X, Huang T, et al. Prevalence of Mitochondrial ND4 Mutations in 1281 Han Chinese Subjects With Leber's Hereditary Optic Neuropathy. Investigative Ophthalmology & Visual Science. 56: 4778-88. PMID 26218905 DOI: 10.1167/Iovs.14-16158 |
0.361 |
|
| 2015 |
Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, ... ... Huang T, et al. Metabolic rescue in pluripotent cells from patients with mtDNA disease. Nature. PMID 26176921 DOI: 10.1038/Nature14546 |
0.444 |
|
| 2015 |
Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV, Tao F, Speziani F, Abreu L, Schüle R, Caporali L, ... ... Huang T, et al. Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nature Genetics. 47: 926-32. PMID 26168012 DOI: 10.1038/Ng.3354 |
0.407 |
|
| 2015 |
Barber JC, Rosenfeld JA, Graham JM, Kramer N, Lachlan KL, Bateman MS, Collinson MN, Stadheim BF, Turner CL, Gauthier JN, Reimschisel TE, Qureshi AM, Dabir TA, Humphreys MW, Marble M, ... Huang T, et al. Inside the 8p23.1 duplication syndrome; eight microduplications of likely or uncertain clinical significance. American Journal of Medical Genetics. Part A. PMID 26097203 DOI: 10.1002/Ajmg.A.37120 |
0.338 |
|
| 2015 |
Riazifar H, Sun G, Wang X, Rupp A, Vemaraju S, Ross-Cisneros FN, Lang RA, Sadun AA, Hattar S, Guan MX, Huang T. Phenotypic and functional characterization of Bst+/- mouse retina. Disease Models & Mechanisms. PMID 26035379 DOI: 10.1242/Dmm.018176 |
0.339 |
|
| 2015 |
Simon M, Richard EM, Wang X, Shahzad M, Huang VH, Qaiser TA, Potluri P, Mahl SE, Davila A, Nazli S, Hancock S, Yu M, Gargus J, Chang R, Al-Sheqaih N, ... ... Huang T, et al. Mutations of human NARS2, encoding the mitochondrial asparaginyl-tRNA synthetase, cause nonsyndromic deafness and Leigh syndrome. Plos Genetics. 11: e1005097. PMID 25807530 DOI: 10.1016/J.Mito.2015.07.089 |
0.446 |
|
| 2015 |
Hufnagel RB, Arno G, Hein ND, Hersheson J, Prasad M, Anderson Y, Krueger LA, Gregory LC, Stoetzel C, Jaworek TJ, Hull S, Li A, Plagnol V, Willen CM, Morgan TM, ... ... Huang T, et al. Neuropathy target esterase impairments cause Oliver-McFarlane and Laurence-Moon syndromes. Journal of Medical Genetics. 52: 85-94. PMID 25480986 DOI: 10.1136/Jmedgenet-2014-102856 |
0.355 |
|
| 2015 |
Koski A, Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, ... ... Huang T, et al. Genetically and metabolically corrected pluripotent stem cells from patients with mtDNA disease Mitochondrion. 24: S38. DOI: 10.1016/J.Mito.2015.07.106 |
0.304 |
|
| 2015 |
Peng Y, Gong S, Liu X, Li Z, Wu Q, Zhao X, Wang X, Guan M, Huang T. Mitochondrial tRNAHis 12201T>C mutation influence the deafness by altering the mitochondrial function Mitochondrion. 24: S29-S30. DOI: 10.1016/J.Mito.2015.07.084 |
0.371 |
|
| 2014 |
Gong S, Peng Y, Jiang P, Wang M, Fan M, Wang X, Zhou H, Li H, Yan Q, Huang T, Guan MX. A deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential. Nucleic Acids Research. 42: 8039-48. PMID 24920829 DOI: 10.1093/Nar/Gku466 |
0.423 |
|
| 2014 |
Riazifar H, Jia Y, Chen J, Lynch G, Huang T. Chemically induced specification of retinal ganglion cells from human embryonic and induced pluripotent stem cells. Stem Cells Translational Medicine. 3: 424-32. PMID 24493857 DOI: 10.1016/J.Mito.2013.07.016 |
0.335 |
|
| 2014 |
Esmailpour T, Riazifar H, Liu L, Donkervoort S, Huang VH, Madaan S, Shoucri BM, Busch A, Wu J, Towbin A, Chadwick RB, Sequeira A, Vawter MP, Sun G, Johnston JJ, ... ... Huang T, et al. A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome. Journal of Medical Genetics. 51: 185-96. PMID 24431331 DOI: 10.1136/Jmedgenet-2013-101660 |
0.68 |
|
| 2013 |
Zhang J, Zhao F, Fu Q, Liang M, Tong Y, Liu X, Lin B, Mi H, Zhang M, Wei QP, Xue L, Jiang P, Zhou X, Mo JQ, Huang T, et al. Mitochondrial haplotypes may modulate the phenotypic manifestation of the LHON-associated m.14484T>C (MT-ND6) mutation in Chinese families. Mitochondrion. 13: 772-81. PMID 23665487 DOI: 10.1016/J.Mito.2013.05.002 |
0.367 |
|
| 2013 |
Fan Y, Steller J, Gonzalez IL, Kulik W, Fox M, Chang R, Westerfield BA, Batra AS, Wang RY, Gallant NM, Pena LS, Wang H, Huang T, Bhuta S, Penny DJ, et al. A Novel Exonic Splicing Mutation in the TAZ (G4.5) Gene in a Case with Atypical Barth Syndrome. Jimd Reports. 11: 99-106. PMID 23606313 DOI: 10.1007/8904_2013_228 |
0.335 |
|
| 2012 |
Zhang C, Huang VH, Simon M, Sharma LK, Fan W, Haas R, Wallace DC, Bai Y, Huang T. Heteroplasmic mutations of the mitochondrial genome cause paradoxical effects on mitochondrial functions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4914-24. PMID 22925728 DOI: 10.1096/Fj.12-206532 |
0.394 |
|
| 2012 |
Esmailpour T, Huang T. TBX3 promotes human embryonic stem cell proliferation and neuroepithelial differentiation in a differentiation stage-dependent manner. Stem Cells (Dayton, Ohio). 30: 2152-63. PMID 22865636 DOI: 10.1002/Stem.1187 |
0.691 |
|
| 2012 |
Strehle EM, Yu L, Rosenfeld JA, Donkervoort S, Zhou Y, Chen TJ, Martinez JE, Fan YS, Barbouth D, Zhu H, Vaglio A, Smith R, Stevens CA, Curry CJ, Ladda RL, ... ... Huang T, et al. Genotype-phenotype analysis of 4q deletion syndrome: proposal of a critical region. American Journal of Medical Genetics. Part A. 158: 2139-51. PMID 22847869 DOI: 10.1002/Ajmg.A.35502 |
0.314 |
|
| 2012 |
Ji F, Sharpley MS, Derbeneva O, Alves LS, Qian P, Wang Y, Chalkia D, Lvova M, Xu J, Yao W, Simon M, Platt J, Xu S, Angelin A, Davila A, ... Huang T, et al. Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans. Proceedings of the National Academy of Sciences of the United States of America. 109: 7391-6. PMID 22517755 DOI: 10.1073/Pnas.1202484109 |
0.318 |
|
| 2011 |
Liu J, Esmailpour T, Shang X, Gulsen G, Liu A, Huang T. TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model. Bmc Developmental Biology. 11: 65. PMID 22039763 DOI: 10.1186/1471-213X-11-65 |
0.709 |
|
| 2011 |
Santarelli R, Starr A, Del Castillo I, Huang T, Scimemi P, Cama E, Rossi R, Arslan E. Presynaptic and postsynaptic mechanisms underlying auditory neuropathy in patients with mutations in the OTOF or OPA1 gene Audiological Medicine. 9: 59-66. DOI: 10.3109/1651386X.2011.558764 |
0.32 |
|
| 2009 |
Shahrestani P, Leung HT, Le PK, Pak WL, Tse S, Ocorr K, Huang T. Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner. Plos One. 4: e6867. PMID 19718456 DOI: 10.1016/J.Mito.2009.12.054 |
0.428 |
|
| 2008 |
Yarosh W, Barrientos T, Esmailpour T, Lin L, Carpenter PM, Osann K, Anton-Culver H, Huang T. TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases. Cancer Research. 68: 693-9. PMID 18245468 DOI: 10.1158/0008-5472.Can-07-5012 |
0.688 |
|
| 2004 |
Fan W, Huang X, Chen C, Gray J, Huang T. TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines. Cancer Research. 64: 5132-9. PMID 15289316 DOI: 10.1158/0008-5472.Can-04-0615 |
0.432 |
|
| 2002 |
Huang T. Current advances in Holt-Oram syndrome Current Opinion in Pediatrics. 14: 691-695. PMID 12436037 DOI: 10.1097/00008480-200212000-00008 |
0.337 |
|
| Show low-probability matches. |