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Jermaine L. Jenkins, Ph.D. - Publications

Affiliations: 
2006 University of Missouri - Columbia, Columbia, MO, United States 
Area:
Biochemistry
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Srivastava Y, Blau ME, Jenkins JL, Wedekind JE. Full-Length NAD-I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate. Biochemistry. PMID 37947391 DOI: 10.1021/acs.biochem.3c00391  0.355
2023 Schroeder GM, Kiliushik D, Jenkins JL, Wedekind JE. Structure and function analysis of a type III preQ-I riboswitch from E. coli reveals direct metabolite-sensing by the Shine-Dalgarno sequence. The Journal of Biological Chemistry. 105208. PMID 37660906 DOI: 10.1016/j.jbc.2023.105208  0.361
2023 Schroeder GM, Akinyemi O, Malik J, Focht CM, Pritchett EM, Baker CD, McSally JP, Jenkins JL, Mathews DH, Wedekind JE. A riboswitch separated from its ribosome-binding site still regulates translation. Nucleic Acids Research. PMID 36762498 DOI: 10.1093/nar/gkad056  0.375
2022 Galardi JW, Bela VN, Jeffery N, He X, Glasser E, Loerch S, Jenkins JL, Pulvino MJ, Boutz PL, Kielkopf CL. A UHM - ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. The Journal of Biological Chemistry. 102224. PMID 35780835 DOI: 10.1016/j.jbc.2022.102224  0.454
2022 Glasser E, Maji D, Biancon G, Puthenpeedikakkal AMK, Cavender CE, Tebaldi T, Jenkins JL, Mathews DH, Halene S, Kielkopf CL. Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Research. PMID 35524551 DOI: 10.1093/nar/gkac287  0.431
2022 Schroeder GM, Cavender CE, Blau ME, Jenkins JL, Mathews DH, Wedekind JE. A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control. Nature Communications. 13: 199. PMID 35017488 DOI: 10.1038/s41467-021-27790-8  0.332
2021 Srivastava Y, Bonn-Breach R, Chavali SS, Lippa GM, Jenkins JL, Wedekind JE. Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing. Crystals. 11. PMID 33777416 DOI: 10.3390/cryst11030273  0.343
2020 Maji D, Glasser E, Henderson S, Galardi J, Pulvino MJ, Jenkins JL, Kielkopf CL. Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. The Journal of Biological Chemistry. 295: 17148-17157. PMID 33453965 DOI: 10.1074/jbc.RA120.015339  0.366
2020 Chavali SS, Mali SM, Jenkins JL, Fasan R, Wedekind JE. Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. The Journal of Biological Chemistry. 295: 16470-16486. PMID 33453887 DOI: 10.1074/jbc.RA120.015444  0.347
2020 Sparks RP, Arango AS, Jenkins JL, Guida WC, Tajkhorshid E, Sparks CE, Sparks JD, Fratti RA. An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes. Biochemistry. PMID 33153264 DOI: 10.1021/acs.biochem.0c00741  0.325
2020 Chavali SS, Mali SM, Jenkins JL, Fasan R, Wedekind JE. Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. The Journal of Biological Chemistry. PMID 33051202 DOI: 10.1074/jbc.RA120.015444  0.348
2020 Maji D, Glasser E, Henderson S, Galardi J, Pulvino MJ, Jenkins JL, Kielkopf CL. Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. The Journal of Biological Chemistry. PMID 33020180 DOI: 10.1074/jbc.RA120.015339  0.36
2020 Schroeder GM, Dutta D, Cavender CE, Jenkins JL, Pritchett EM, Baker CD, Ashton JM, Mathews DH, Wedekind JE. Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation. Nucleic Acids Research. PMID 32597951 DOI: 10.1093/Nar/Gkaa546  0.423
2019 Bonn-Breach R, Gu Y, Jenkins J, Fasan R, Wedekind J. Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design. Acta Crystallographica. Section D, Structural Biology. 75: 969-979. PMID 31692471 DOI: 10.1107/S2059798319012890  0.43
2019 Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion. The Journal of Biological Chemistry. PMID 31515268 DOI: 10.1074/Jbc.Ra119.008865  0.371
2019 Talkish J, Igel H, Hunter O, Horner SW, Jeffery NN, Leach JR, Jenkins JL, Kielkopf CL, Ares M. Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction. Rna (New York, N.Y.). PMID 31110137 DOI: 10.1261/Rna.070649.119  0.489
2019 Starr ML, Sparks RP, Arango AS, Hurst LR, Zhao Z, Lihan M, Jenkins JL, Tajkhorshid E, Fratti RA. Phosphatidic acid induces conformational changes in Sec18 protomers that prevent SNARE priming. The Journal of Biological Chemistry. PMID 30617180 DOI: 10.1074/Jbc.Ra118.006552  0.382
2019 Sparks RP, Jenkins JL, Fratti R. Use of Surface Plasmon Resonance (SPR) to Determine Binding Affinities and Kinetic Parameters Between Components Important in Fusion Machinery. Methods in Molecular Biology (Clifton, N.J.). 1860: 199-210. PMID 30317506 DOI: 10.1007/978-1-4939-8760-3_12  0.38
2019 Chavali SS, Belashov IA, Jenkins J, Wedekind JE. Structural characterization of lab-evolved proteins reveals signature sequences required for high-affinity binding to HIV-1 TAR RNA Acta Crystallographica Section a Foundations and Advances. 75: a132-a132. DOI: 10.1107/S0108767319098672  0.433
2019 Glasser E, Maji D, Henderson S, Pulvino M, Jenkins JL, Kielkopf CL. The essential pre-mRNA splicing factor U2AF65 accommodates divergent nucleotides at the central position of the polypyrimidine 3′ splice site signal Acta Crystallographica Section a Foundations and Advances. 75: a134-a134. DOI: 10.1107/S0108767319098659  0.351
2019 Shashank Chavali S, Belashov I, Jenkins J, Wedekind J. Structural Characterization of a Peptide Derived from a Lab-Evolved Protein that Targets HIV-1 TAR RNA Biophysical Journal. 116: 501a-502a. DOI: 10.1016/J.Bpj.2018.11.2706  0.308
2018 Loerch S, Leach JR, Horner SW, Maji D, Jenkins JL, Pulvino M, Kielkopf CL. The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. The Journal of Biological Chemistry. PMID 30567737 DOI: 10.2210/Pdb6N3D/Pdb  0.503
2018 Maji D, Glasser E, Jenkins JL, Kielkopf CL. Cancer-associated mutations of the pre-mRNA splicing factor U2AF2 alter splice site signal recognition Acta Crystallographica Section a Foundations and Advances. 74: a232-a232. DOI: 10.1107/S0108767318097672  0.328
2017 Glasser E, Agrawal A, Jenkins JL, Kielkopf CL. Cancer-associated mutations mapped on high resolution structures of the U2AF2 RNA recognition motifs. Biochemistry. PMID 28850223 DOI: 10.1021/Acs.Biochem.7B00551  0.357
2017 Wedekind JE, Dutta D, Belashov IA, Jenkins JL. Metalloriboswitches: RNA-Based Inorganic Ion Sensors that Regulate Genes. The Journal of Biological Chemistry. PMID 28455443 DOI: 10.1074/Jbc.R117.787713  0.308
2017 Jenkins JL, Kielkopf CL. Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures. Trends in Genetics : Tig. PMID 28372848 DOI: 10.1016/J.Tig.2017.03.001  0.407
2016 Clark KM, Jenkins JL, Fedoriw N, Dumont ME. Human CaaX Protease ZMPSTE24 Expressed in Yeast: Structure and Inhibition by HIV Protease Inhibitors. Protein Science : a Publication of the Protein Society. PMID 27774687 DOI: 10.1002/Pro.3074  0.402
2016 Sparks RP, Jenkins JL, Miner GE, Wang Y, Guida WC, Sparks CE, Fratti RA, Sparks JD. Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding. Biochemical and Biophysical Research Communications. PMID 27666481 DOI: 10.1016/J.Bbrc.2016.09.108  0.444
2016 Jenkins JL, Wedekind JE. The Quick and the Dead: A Guide to Fast Phasing of Small Ribozyme and Riboswitch Crystal Structures. Methods in Molecular Biology (Clifton, N.J.). 1490: 265-80. PMID 27665605 DOI: 10.1007/978-1-4939-6433-8_17  0.358
2016 Agrawal AA, Salsi E, Chatrikhi R, Henderson S, Jenkins JL, Green MR, Ermolenko DN, Kielkopf CL. An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nature Communications. 7: 10950. PMID 26952537 DOI: 10.1038/Ncomms10950  0.518
2014 Liberman JA, Bogue JT, Jenkins JL, Salim M, Wedekind JE. ITC analysis of ligand binding to preQ₁ riboswitches. Methods in Enzymology. 549: 435-50. PMID 25432759 DOI: 10.1016/B978-0-12-801122-5.00018-0  0.431
2014 Agrawal AA, McLaughlin KJ, Jenkins JL, Kielkopf CL. Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proceedings of the National Academy of Sciences of the United States of America. 111: 17420-5. PMID 25422459 DOI: 10.1073/Pnas.1412743111  0.468
2013 Jenkins JL, Agrawal AA, Gupta A, Green MR, Kielkopf CL. U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Research. 41: 3859-73. PMID 23376934 DOI: 10.1093/Nar/Gkt046  0.485
2012 Liberman JA, Guo M, Jenkins JL, Krucinska J, Chen Y, Carey PR, Wedekind JE. A transition-state interaction shifts nucleobase ionization toward neutrality to facilitate small ribozyme catalysis. Journal of the American Chemical Society. 134: 16933-6. PMID 22989273 DOI: 10.1021/Ja3070528  0.37
2012 Jenkins JL, Laird KM, Kielkopf CL. A Broad range of conformations contribute to the solution ensemble of the essential splicing factor U2AF(65). Biochemistry. 51: 5223-5. PMID 22702716 DOI: 10.1021/Bi300277T  0.449
2012 Lippa GM, Liberman JA, Jenkins JL, Krucinska J, Salim M, Wedekind JE. Crystallographic analysis of small ribozymes and riboswitches. Methods in Molecular Biology (Clifton, N.J.). 848: 159-84. PMID 22315069 DOI: 10.1007/978-1-61779-545-9_11  0.374
2012 Bauer WJ, Heath J, Jenkins JL, Kielkopf CL. Three RNA recognition motifs participate in RNA recognition and structural organization by the pro-apoptotic factor TIA-1. Journal of Molecular Biology. 415: 727-40. PMID 22154808 DOI: 10.1016/J.Jmb.2011.11.040  0.452
2011 Jenkins JL, Krucinska J, McCarty RM, Bandarian V, Wedekind JE. Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation. The Journal of Biological Chemistry. 286: 24626-37. PMID 21592962 DOI: 10.1074/Jbc.M111.230375  0.463
2011 McLaughlin KJ, Jenkins JL, Kielkopf CL. Large favorable enthalpy changes drive specific RNA recognition by RNA recognition motif proteins. Biochemistry. 50: 1429-31. PMID 21261285 DOI: 10.1021/Bi102057M  0.45
2011 Gupta A, Jenkins JL, Kielkopf CL. RNA induces conformational changes in the SF1/U2AF65 splicing factor complex. Journal of Molecular Biology. 405: 1128-38. PMID 21146534 DOI: 10.1016/J.Jmb.2010.11.054  0.38
2009 Williams KJ, Jenkins JL, Kielkopf CL. Thermodynamic Characteristics of pre-mRNA Splice Site Recognition Biophysical Journal. 96: 63a-64a. DOI: 10.1016/J.Bpj.2008.12.226  0.48
2008 Jenkins JL, Shen H, Green MR, Kielkopf CL. Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65. The Journal of Biological Chemistry. 283: 33641-9. PMID 18842594 DOI: 10.1074/Jbc.M806297200  0.501
2008 Zhou Y, Larson JD, Bottoms CA, Arturo EC, Henzl MT, Jenkins JL, Nix JC, Becker DF, Tanner JJ. Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA. Journal of Molecular Biology. 381: 174-88. PMID 18586269 DOI: 10.1016/J.Jmb.2008.05.084  0.649
2006 Larson JD, Jenkins JL, Schuermann JP, Zhou Y, Becker DF, Tanner JJ. Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition. Protein Science : a Publication of the Protein Society. 15: 2630-41. PMID 17001030 DOI: 10.1110/Ps.062425706  0.664
2006 Jenkins JL, Tanner JJ. High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase. Acta Crystallographica. Section D, Biological Crystallography. 62: 290-301. PMID 16510976 DOI: 10.1107/S0907444905042289  0.595
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