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Michael Jirousek - Publications

Affiliations: 
Chemistry Case Western Reserve University, Cleveland Heights, OH, United States 
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Yoshizaki T, Milne JC, Imamura T, Schenk S, Sonoda N, Babendure JL, Lu JC, Smith JJ, Jirousek MR, Olefsky JM. SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. Molecular and Cellular Biology. 29: 1363-74. PMID 19103747 DOI: 10.1128/Mcb.00705-08  0.315
2007 Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, ... ... Jirousek MR, et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 450: 712-6. PMID 18046409 DOI: 10.1038/Nature06261  0.306
2004 Rondinone CM, Clampit J, Gum RJ, Zinker BA, Jirousek MR, Trevillyan JM. Reduction of PTP1B induces differential expression of PI3-kinase (p85alpha) isoforms. Biochemical and Biophysical Research Communications. 323: 652-9. PMID 15369800 DOI: 10.1016/j.bbrc.2004.08.138  0.389
2003 Liu G, Szczepankiewicz BG, Pei Z, Janowick DA, Xin Z, Hajduk PJ, Abad-Zapatero C, Liang H, Hutchins CW, Fesik SW, Ballaron SJ, Stashko MA, Lubben T, Mika AK, Zinker BA, ... ... Jirousek MR, et al. Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. Journal of Medicinal Chemistry. 46: 2093-103. PMID 12747781 DOI: 10.1021/Jm0205696  0.329
2003 Szczepankiewicz BG, Liu G, Hajduk PJ, Abad-Zapatero C, Pei Z, Xin Z, Lubben TH, Trevillyan JM, Stashko MA, Ballaron SJ, Liang H, Huang F, Hutchins CW, Fesik SW, Jirousek MR. Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy. Journal of the American Chemical Society. 125: 4087-96. PMID 12670229 DOI: 10.1021/Ja0296733  0.31
2003 Gum RJ, Gaede LL, Koterski SL, Heindel M, Clampit JE, Zinker BA, Trevillyan JM, Ulrich RG, Jirousek MR, Rondinone CM. Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice. Diabetes. 52: 21-8. PMID 12502489  0.305
2002 Zinker BA, Rondinone CM, Trevillyan JM, Gum RJ, Clampit JE, Waring JF, Xie N, Wilcox D, Jacobson P, Frost L, Kroeger PE, Reilly RM, Koterski S, Opgenorth TJ, Ulrich RG, ... ... Jirousek MR, et al. PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 11357-62. PMID 12169659 DOI: 10.1073/pnas.142298199  0.404
1998 Aiello LP, Bursell SE, Clermont A, Duh E, Ishii H, Takagi C, Mori F, Ciulla TA, Ways K, Jirousek M, Smith LEH, King GL. Vascular Endothelial Growth Factor-Induced Retinal Permeability is Mediated by Protein Kinase C In Vivo and Suppressed by an Orally Effective β-Isoform-Selective Inhibitor. Retina-the Journal of Retinal and Vitreous Diseases. 18: 492. DOI: 10.1097/00006982-199805000-00033  0.364
1997 Aiello LP, Bursell SE, Clermont A, Duh E, Ishii H, Takagi C, Mori F, Ciulla TA, Ways K, Jirousek M, Smith LE, King GL. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes. 46: 1473-80. PMID 9287049 DOI: 10.2337/Diab.46.9.1473  0.356
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