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Hector Floyd DeLuca - Publications

Affiliations: 
Biochemistry University of Wisconsin, Madison, Madison, WI 
Area:
vitamins A and D
Website:
http://www.biochem.wisc.edu/faculty/deluca/default.aspx
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Year Citation  Score
2024 Fabisiak A, Brzeminski P, Sicinski RR, Rochel N, Maj E, Filip-Psurska B, Wietrzyk J, Plum LA, DeLuca HF. Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D analogs and their crystal structures with the vitamin D nuclear receptor. European Journal of Medicinal Chemistry. 271: 116403. PMID 38615411 DOI: 10.1016/j.ejmech.2024.116403  0.542
2022 Plum LA, Blaser W, Peter L, Prahl J, Seeman J, DeLuca HF. Antibody production in mice requires neither vitamin D, nor the vitamin D receptor. Frontiers in Immunology. 13: 960405. PMID 36341456 DOI: 10.3389/fimmu.2022.960405  0.514
2022 Irving AA, Waters BJ, Seeman JR, Plum LA, DeLuca HF. Vitamin D receptor absence does not enhance intestinal tumorigenesis in ApcPirc/+rats. Biology Open. 11. PMID 35662320 DOI: 10.1242/bio.059290  0.469
2022 Duchow EG, Sibilska-Kaminski IK, Plum LA, DeLuca HF. Vitamin D esters are the major form of vitamin D produced by UV irradiation in mice. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 35488978 DOI: 10.1007/s43630-022-00230-2  0.54
2022 Sibilska-Kaminski IK, Fabisiak A, Brzeminski P, Plum LA, Sicinski RR, DeLuca HF. Novel superagonist analogs of 2-methylene calcitriol: Design, molecular docking, synthesis and biological evaluation. Bioorganic Chemistry. 118: 105416. PMID 34798456 DOI: 10.1016/j.bioorg.2021.105416  0.42
2021 Duchow EG, Duchow MW, Plum LA, DeLuca HF. Vitamin D binding protein greatly improves bioactivity but is not essential for orally administered vitamin D. Physiological Reports. 9: e15138. PMID 34873873 DOI: 10.14814/phy2.15138  0.538
2020 Sibilska-Kaminski I, Sicinski RR, Plum LA, Deluca HF. Synthesis and Biological Activity of 2,22-Dimethylene Analogues of 19-Norcalcitriol and Related Compounds. Journal of Medicinal Chemistry. PMID 32510210 DOI: 10.1021/Acs.Jmedchem.0C00580  0.469
2019 Duchow EG, Cooke NE, Seeman J, Plum LA, DeLuca HF. Vitamin D binding protein is required to utilize skin-generated vitamin D. Proceedings of the National Academy of Sciences of the United States of America. PMID 31748273 DOI: 10.1073/Pnas.1915442116  0.625
2019 Irving AA, Marling SJ, Seeman J, Plum LA, DeLuca HF. UV light suppression of EAE (a mouse model of multiple sclerosis) is independent of vitamin D and its receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31636184 DOI: 10.1073/Pnas.1913294116  0.573
2019 Baisa GA, Plum L, Marling S, Seeman J, DeLuca HF. Vitamin D is not required for adaptive immunity to listeria. Physiological Reports. 7: e14209. PMID 31464083 DOI: 10.14814/Phy2.14209  0.535
2019 Plum LA, Zella J, Clagett-Dame M, DeLuca HF. A New 1,25 Dihydroxy Vitamin D Analog with Strong Bone Anabolic Activity in OVX Rats with Little or No Bone Resorptive Activity. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31369169 DOI: 10.1002/Jbmr.3838  0.85
2018 Sempos CT, Heijboer AC, Bikle DD, Bollerslev J, Bouillon R, Brannon PM, DeLuca HF, Jones G, Munns CF, Bilezikian JP, Giustina A, Binkley N. Vitamin D Assays and the Definition of Hypovitaminosis D: Results from the 1 International Conference on Controversies in Vitamin D. British Journal of Clinical Pharmacology. PMID 29851137 DOI: 10.1111/Bcp.13652  0.62
2018 Irving AA, Duchow EG, Plum LA, DeLuca HF. Vitamin D deficiency in therat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective. Disease Models & Mechanisms. 11. PMID 29590632 DOI: 10.1242/Dmm.032300  0.538
2018 Tomasini-Johansson B, O'Brien C, Larson-Osborne A, Toraason I, Hullett D, Plum L, DeLuca H, Sollinger H. Effects of the Vitamin D Analog 2AMD in Cyclosporine-Induced Nephrotoxicity: Dose-Response and Antifibrotic Activity. Experimental and Clinical Transplantation : Official Journal of the Middle East Society For Organ Transplantation. 15: 641-647. PMID 29219791  0.465
2018 DeLuca HF, Plum L. UVB radiation, vitamin D and multiple sclerosis. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 16: 411-415. PMID 27910985 DOI: 10.1039/c6pp00308g  0.507
2017 Ahrens JM, Jones JD, Nieves NJ, Mitzey AM, DeLuca HF, Clagett-Dame M. Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid. Plos One. 12: e0188887. PMID 29182680 DOI: 10.1371/Journal.Pone.0188887  0.801
2017 Pandey R, Zella JB, Zhu JG, Plum LA, Clagett-Dame M, Blaser WJ, Bedale W, DeLuca HF, Coyne DW. Pharmacokinetics of a New Oral Vitamin D Receptor Activator (2-Methylene-19-Nor-(20S)-1α,25-Dihydroxyvitamin D3) in Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism on Hemodialysis. Drugs in R&D. PMID 28905271 DOI: 10.1007/S40268-017-0210-Z  0.863
2017 Taban IM, Zhu J, DeLuca HF, Simons C. Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements. Bioorganic & Medicinal Chemistry. PMID 28886997 DOI: 10.1016/J.Bmc.2017.08.036  0.398
2017 Taban IM, Zhu J, DeLuca HF, Simons C. Synthesis, molecular modelling and CYP24A1 inhibitory activity of novel of (E)-N-(2-(1H-imidazol-1-yl)-2-(phenylethyl)-3/4-styrylbenzamides. Bioorganic & Medicinal Chemistry. PMID 28601511 DOI: 10.1016/J.Bmc.2017.05.055  0.399
2017 Szybinski M, Sektas K, Sicinski RR, Plum LA, Frelek J, DeLuca HF. Design, Synthesis and Biological Properties of Seco-D-Ring Modified 1α,25-Dihydroxyvitamin D3 Analogues. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28285018 DOI: 10.1016/J.Jsbmb.2017.03.006  0.567
2017 Irving AA, Marling SJ, Plum LA, DeLuca HF. Suppression of experimental autoimmune encephalomyelitis by ultraviolet light is not mediated by isomerization of urocanic acid. Bmc Neuroscience. 18: 8. PMID 28056806 DOI: 10.1186/S12868-016-0323-2  0.398
2017 Chiellini G, Rapposelli S, Nesi G, Sestito S, Sabatini M, Zhu J, Massarelli I, Plum LA, Clagett-Dame M, DeLuca HF. Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D-Like CYP24A1 Inhibitors Chemistryselect. 2: 8346-8353. DOI: 10.1002/slct.201701835  0.468
2016 Thadhani R, Zella JB, Knutson DC, Blaser WJ, Plum LA, Clagett-Dame M, Buck RD, DeLuca HF. 2MD (DP001), a Single Agent in the Management of Hemodialysis Patients: A Randomized Trial. American Journal of Nephrology. 45: 40-48. PMID 27880946 DOI: 10.1159/000452680  0.839
2016 Szybinski M, Sokołowska K, Sicinski RR, Plum LA, DeLuca HF. D-seco-Vitamin D analogs having reversed configurations at C-13 and C-14: Synthesis, docking studies and biological evaluation. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27576086 DOI: 10.1016/J.Jsbmb.2016.08.009  0.574
2016 Rosenberg JE, Astor BC, Deluca HF, Yevzlin AS. The association of mineral metabolism with vascular access patency. The Journal of Vascular Access. 0. PMID 27470251 DOI: 10.5301/Jva.5000584  0.447
2016 Wang Y, Marling SJ, Martino VM, Prahl JM, Deluca HF. The absence of 25-hydroxyvitamin D3-1α-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27108944 DOI: 10.1016/J.Jsbmb.2016.04.010  0.424
2016 Pandey R, Zella J, Clagett-Dame M, Plum LA, DeLuca HF, Coyne DW. Use of 2MD, a Novel Oral Calcitriol Analog, in Hemodialysis Patients with Secondary Hyperparathyroidism. American Journal of Nephrology. 43: 213-220. PMID 27096733 DOI: 10.1159/000445756  0.852
2016 DeLuca HF, Plum LA. Analogs of 1α,25-Dihydroxyvitamin D3 in Clinical Use. Vitamins and Hormones. 100: 151-64. PMID 26827952 DOI: 10.1016/Bs.Vh.2015.11.002  0.482
2016 DeLuca HF. Vitamin D: Historical Overview. Vitamins and Hormones. 100: 1-20. PMID 26827946 DOI: 10.1016/Bs.Vh.2015.11.001  0.622
2015 Kulesza U, Plum LA, DeLuca HF, Mouriño A, Sicinski RR. A new suprasterol by photochemical reaction of 1α,25-dihydroxy-9-methylene-19-norvitamin D3. Organic & Biomolecular Chemistry. PMID 26693597 DOI: 10.1039/C5Ob01896J  0.376
2015 Flores AA, Massarelli I, Thoden JB, Plum LA, Deluca HF. A Methylene Group on C-2 of 24,24-Difluoro-19-nor-1α,25-Dihydroxyvitamin D3 Markedly Increases Bone Calcium Mobilization in vivo. Journal of Medicinal Chemistry. PMID 26630444 DOI: 10.1021/Acs.Jmedchem.5B01564  0.564
2015 Sibilska IK, Szybinski M, Sicinski RR, Plum LA, Deluca HF. Synthesis and Biological Activity of 2-Methylene Analogues of Calcitriol and Related Compounds. Journal of Medicinal Chemistry. PMID 26574921 DOI: 10.1021/acs.jmedchem.5b01295  0.421
2015 Valcour A, Zierold C, Podgorski AL, Olson GT, Wall JV, DeLuca HF, Bonelli F. A novel, fully-automated, chemiluminescent assay for the detection of 1,25-dihydroxyvitamin D in biological samples. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26303747 DOI: 10.1016/J.Jsbmb.2015.08.005  0.59
2015 Kulesza U, Plum LA, DeLuca HF, Mouriño A, Sicinski RR. Novel 9-Alkyl- and 9-Alkylidene-Substituted 1α,25-Dihydroxyvitamin D3 Analogues: Synthesis and Biological Examinations. Journal of Medicinal Chemistry. 58: 6237-47. PMID 26206427 DOI: 10.1021/Acs.Jmedchem.5B00795  0.558
2015 Lee SM, Riley EM, Meyer MB, Benkusky NA, Plum LA, DeLuca HF, Pike JW. 1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components. The Journal of Biological Chemistry. 290: 18199-215. PMID 26041780 DOI: 10.1074/Jbc.M115.665794  0.579
2015 Sundersingh F, Plum LA, DeLuca HF. Vitamin D deficiency independent of hypocalcemia elevates blood pressure in rats Biochemical and Biophysical Research Communications. 461: 589-591. PMID 25911319 DOI: 10.1016/J.Bbrc.2015.04.069  0.577
2015 Irving AA, Plum LA, Blaser WJ, Ford MR, Weng C, Clipson L, DeLuca HF, Dove WF. Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer. The Journal of Nutrition. 145: 291-8. PMID 25644350 DOI: 10.3945/Jn.114.204396  0.47
2015 Wang Y, Zhu J, Deluca HF. The vitamin D receptor in the proximal renal tubule is a key regulator of serum 1α,25-dihydroxyvitamin D3 American Journal of Physiology - Endocrinology and Metabolism. 308: E201-E205. PMID 25425001 DOI: 10.1152/Ajpendo.00422.2014  0.625
2015 DeLuca HF. Is there more to learn about functional vitamin D metabolism? Journal of Steroid Biochemistry and Molecular Biology. 148: 3-6. PMID 25194637 DOI: 10.1016/J.Jsbmb.2014.08.020  0.632
2014 Ferla S, Gomaa MS, Brancale A, Zhu J, Ochalek JT, Deluca HF, Simons C. Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation European Journal of Medicinal Chemistry. 87: 39-51. PMID 25240094 DOI: 10.1016/J.Ejmech.2014.09.035  0.402
2014 Sibilska IK, Sicinski RR, Ochalek JT, Plum LA, Deluca HF. Synthesis and biological activity of 25-hydroxy-2-methylene-vitamin D3 analogues monohydroxylated in the A-ring Journal of Medicinal Chemistry. 57: 8319-8331. PMID 25221942 DOI: 10.1021/Jm500750B  0.55
2014 Ferla S, Aboraia AS, Brancale A, Pepper CJ, Zhu J, Ochalek JT, Deluca HF, Simons C. Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation Journal of Medicinal Chemistry. 57: 7702-7715. PMID 25148392 DOI: 10.1021/Jm5009314  0.438
2014 Zella JB, Plum LA, Plowchalk DR, Potochoiba M, Clagett-Dame M, Deluca HF. Novel, selective vitamin D analog suppresses parathyroid hormone in uremic animals and postmenopausal women American Journal of Nephrology. 39: 476-483. PMID 24854296 DOI: 10.1159/000362846  0.856
2014 Deluca HF. The development of a bone- and parathyroid-specific analog of vitamin D: 2-methylene-19-Nor-(20S)-1α,25-dihydroxyvitamin D3. Bonekey Reports. 3: 514. PMID 24818006 DOI: 10.1038/Bonekey.2014.9  0.559
2014 Kaufmann M, Gallagher JC, Peacock M, Schlingmann KP, Konrad M, DeLuca HF, Sigueiro R, Lopez B, Mourino A, Maestro M, St-Arnaud R, Finkelstein JS, Cooper DP, Jones G. Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD. The Journal of Clinical Endocrinology and Metabolism. 99: 2567-74. PMID 24670084 DOI: 10.1210/Jc.2013-4388  0.532
2014 Chiellini G, Grzywacz P, Plum LA, Clagett-Dame M, Deluca HF. 26-Desmethyl-2-methylene-22-ene-19-nor-1α,25-dihydroxyvitamin D 3 compounds selectively active on intestine Steroids. 83: 27-38. PMID 24513051 DOI: 10.1016/J.Steroids.2014.01.012  0.662
2014 Deluca HF. History of the discovery of vitamin D and its active metabolites. Bonekey Reports. 3: 479. PMID 24466410 DOI: 10.1038/Bonekey.2013.213  0.576
2014 DeLuca HF. Triennial Growth Symposium--Vitamin D: bones and beyond Journal of Animal Science. 92: 917-929. PMID 24363329 DOI: 10.2527/jas.2013-7237  0.439
2014 Wang Y, Zhu J, Deluca HF. Identification of the vitamin D receptor in osteoblasts and chondrocytes but not osteoclasts in mouse bone Journal of Bone and Mineral Research. 29: 685-692. PMID 24038189 DOI: 10.1002/Jbmr.2081  0.468
2014 DeLuca HF. Triennial growth symposium-vitamin D: Bones and beyond Journal of Animal Science. 92: 917-929. DOI: 10.2527/jas2013-7237  0.439
2014 Ni Z, Qian J, Yang X, Zhang H, Hang Y, Yan H, Lin A, Huang J, Fang W, Cai J, Yu X, Zhang B, Zhang H, Fang Y, Liu S, ... ... DeLuca HF, et al. Contents Vol. 39, 2014 American Journal of Nephrology. 39. DOI: 10.1159/000365231  0.741
2014 Bouillon R, DeLuca HF, Martin J, Suda T. Introduction to the special issue of BoneKEy Reports on ‘vitamin D and bone’ Ibms Bonekey. 11. DOI: 10.1038/Bonekey.2013.221  0.509
2013 Zhu JG, Ochalek JT, Kaufmann M, Jones G, DeLuca HF. CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo Proceedings of the National Academy of Sciences of the United States of America. 110: 15650-15655. PMID 24019477 DOI: 10.1073/Pnas.1315006110  0.58
2013 Wang Y, Marling SJ, McKnight SM, Danielson AL, Severson KS, Deluca HF. Suppression of experimental autoimmune encephalomyelitis by 300-315nm ultraviolet light. Archives of Biochemistry and Biophysics. 536: 81-6. PMID 23747577 DOI: 10.1016/J.Abb.2013.05.010  0.415
2013 Simon RR, Borzelleca JF, DeLuca HF, Weaver CM. Safety assessment of the post-harvest treatment of button mushrooms (Agaricus bisporus) using ultraviolet light. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 56: 278-89. PMID 23485617 DOI: 10.1016/J.Fct.2013.02.009  0.464
2013 Grzywacz P, Plum LA, Clagett-Dame M, Deluca HF. 26- and 27-Methyl groups of 2-substituted, 19-nor-1α,25- dihydroxylated vitamin D compounds are essential for calcium mobilization in vivo Bioorganic Chemistry. 47: 9-16. PMID 23474215 DOI: 10.1016/J.Bioorg.2013.01.001  0.718
2013 Sibilska IK, Szybinski M, Sicinski RR, Plum LA, DeLuca HF. Highly potent 2-methylene analogs of 1α,25-dihydroxyvitamin D 3: Synthesis and biological evaluation Journal of Steroid Biochemistry and Molecular Biology. 136: 9-13. PMID 23410597 DOI: 10.1016/J.Jsbmb.2013.02.001  0.573
2013 Sibilska I, Sicinski RR, Plum LA, DeLuca HF. Synthesis and biological activity of 25-hydroxy-2-methylene-vitamin D 3 compounds Journal of Steroid Biochemistry and Molecular Biology. 136: 17-22. PMID 23274116 DOI: 10.1016/J.Jsbmb.2012.12.012  0.516
2013 Kulesza U, Mouriño A, Plum LA, DeLuca HF, Sicinski RR. Synthesis of novel 19-norvitamin D3 analogs with unnatural triene system Journal of Steroid Biochemistry and Molecular Biology. 136: 23-26. PMID 23270753 DOI: 10.1016/J.Jsbmb.2012.12.008  0.579
2013 Sokolowska K, Sicinski RR, Mouriño A, Plum LA, DeLuca HF. Synthesis and biological evaluation of novel 6-substituted analogs of 1α,25-dihydroxy-19-norvitamin D3 Journal of Steroid Biochemistry and Molecular Biology. 136: 30-33. PMID 23116698 DOI: 10.1016/J.Jsbmb.2012.10.016  0.54
2013 Glebocka A, Sicinski RR, Plum LA, DeLuca HF. Ring-A-seco analogs of 1α,25-dihydroxy-19-norvitamin D3 Journal of Steroid Biochemistry and Molecular Biology. 136: 39-43. PMID 23064199 DOI: 10.1016/J.Jsbmb.2012.09.030  0.619
2012 Zhu J, Rao H, Tonelli M, Westler WM, Singarapu KK, Markley JL, DeLuca HF, Assadi-Porter FM. Efficient stable isotope labeling and purification of vitamin D receptor from inclusion bodies. Protein Expression and Purification. 85: 25-31. PMID 22750673 DOI: 10.1016/J.Pep.2012.06.012  0.511
2012 Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, Sato M, Penninger JM, Yasuda H, Kato S, DeLuca HF, Suda T, Udagawa N, Takahashi N. Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice Proceedings of the National Academy of Sciences of the United States of America. 109: 10006-10011. PMID 22670054 DOI: 10.1073/Pnas.1207361109  0.357
2012 Wang Y, Marling SJ, Zhu JG, Severson KS, DeLuca HF. Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 8501-4. PMID 22592802 DOI: 10.1073/Pnas.1206054109  0.613
2012 Wang Y, Zhu J, DeLuca HF. Where is the vitamin D receptor? Archives of Biochemistry and Biophysics. 523: 123-133. PMID 22503810 DOI: 10.1016/J.Abb.2012.04.001  0.587
2012 Flores A, Sicinski RR, Grzywacz P, Thoden JB, Plum LA, Clagett-Dame M, Deluca HF. A 20 S combined with a 22 r configuration markedly increases both in vivo and in vitro biological activity of 1α,25-Dihydroxy-22-methyl-2-methylene- 19-norvitamin D 3 Journal of Medicinal Chemistry. 55: 4352-4366. PMID 22490010 DOI: 10.1021/Jm300187X  0.632
2012 Zhu J, Deluca HF. Vitamin D 25-hydroxylase - Four decades of searching, are we there yet? Archives of Biochemistry and Biophysics. 523: 30-36. PMID 22310641 DOI: 10.1016/J.Abb.2012.01.013  0.61
2012 Wang Y, Borchert ML, Deluca HF. Identification of the vitamin D receptor in various cells of the mouse kidney Kidney International. 81: 993-1001. PMID 22278022 DOI: 10.1038/Ki.2011.463  0.576
2012 Kutuzova GD, Gabelt BT, Kiland JA, Hennes-Beann EA, Kaufman PL, DeLuca HF. 1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates. Archives of Biochemistry and Biophysics. 518: 53-60. PMID 22198282 DOI: 10.1016/J.Abb.2011.10.022  0.528
2012 Chiellini G, Rapposelli S, Zhu J, Massarelli I, Saraceno M, Bianucci AM, Plum LA, Clagett-Dame M, Deluca HF. Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase Steroids. 77: 212-223. PMID 22133546 DOI: 10.1016/J.Steroids.2011.11.007  0.726
2012 Singarapu K, Zhu J, Westler W, Deluca H, Markley J. Sequence specific backbone resonance assignment of Vitamin D receptor ligand binding domain (VDRLBD) complexed with 1,25(OH)2 D3 and LXXLL motif (DRIP205) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr17770  0.519
2011 Singarapu KK, Zhu J, Tonelli M, Rao H, Assadi-Porter FM, Westler WM, DeLuca HF, Markley JL. Ligand-specific structural changes in the vitamin D receptor in solution. Biochemistry. 50: 11025-33. PMID 22112050 DOI: 10.1021/Bi201637P  0.527
2011 Plonska-Ocypa K, Sibilska I, Sicinski RR, Sicinska W, Plum LA, Deluca HF. 13,13-Dimethyl-des-C,D analogues of (20S)-1α,25-dihydroxy-2- methylene-19-norvitamin D 3 (2MD): Total synthesis, docking to the VDR, and biological evaluation Bioorganic and Medicinal Chemistry. 19: 7205-7220. PMID 22018918 DOI: 10.1016/J.Bmc.2011.09.048  0.525
2011 Irving AA, Halberg RB, Albrecht DM, Plum LA, Krentz KJ, Clipson L, Drinkwater N, Amos-Landgraf JM, Dove WF, DeLuca HF. Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models. Archives of Biochemistry and Biophysics. 515: 64-71. PMID 21907701 DOI: 10.1016/J.Abb.2011.08.011  0.564
2011 Glebocka A, Sicinski RR, Plum LA, Deluca HF. Synthesis and biological activity of 2-(3′-hydroxypropylidene)- 1α-hydroxy-19-norvitamin D analogues with shortened alkyl side chains Journal of Medicinal Chemistry. 54: 6832-6842. PMID 21902235 DOI: 10.1021/Jm200743P  0.527
2011 Deluca HF, Plum LA. Vitamin D deficiency diminishes the severity and delays onset of experimental autoimmune encephalomyelitis Archives of Biochemistry and Biophysics. 513: 140-143. PMID 21784056 DOI: 10.1016/J.Abb.2011.07.005  0.613
2011 Christakos S, DeLuca HF. Minireview: Vitamin D: Is there a role in extraskeletal health? Endocrinology. 152: 2930-2936. PMID 21673104 DOI: 10.1210/En.2011-0243  0.6
2011 Chiellini G, DeLuca HF. The importance of stereochemistry on the actions of vitamin D Current Topics in Medicinal Chemistry. 11: 840-859. PMID 21291397 DOI: 10.2174/156802611795165016  0.616
2011 Wang Y, DeLuca HF. Is the vitamin D receptor found in muscle? Endocrinology. 152: 354-363. PMID 21190957 DOI: 10.1210/En.2010-1109  0.595
2011 Deluca HF, Prahl JM, Plum LA. 1,25-Dihydroxyvitamin D is not responsible for toxicity caused by vitamin D or 25-hydroxyvitamin D Archives of Biochemistry and Biophysics. 505: 226-230. PMID 20965147 DOI: 10.1016/J.Abb.2010.10.012  0.611
2011 Deluca HF, Bedale W, Binkley N, Gallagher JC, Bolognese M, Peacock M, Aloia J, Clagett-Dame M, Plum L. The vitamin D analogue 2MD increases bone turnover but not BMD in postmenopausal women with osteopenia: Results of a 1-year phase 2 double-blind, placebo-controlled, randomized clinical trial Journal of Bone and Mineral Research. 26: 538-545. PMID 20890933 DOI: 10.1002/Jbmr.256  0.799
2011 DeLuca HF, Plum LA. Alterations in 1,25-dihydroxyvitamin D3 structure that produce profound changes in in vivo activity Vitamin D. 1429-1435. DOI: 10.1016/B978-0-12-381978-9.10074-5  0.359
2010 Plum LA, Deluca HF. Vitamin D, disease and therapeutic opportunities Nature Reviews Drug Discovery. 9: 941-955. PMID 21119732 DOI: 10.1038/Nrd3318  0.588
2010 Grzywacz P, Chiellini G, Plum LA, Clagett-Dame M, Deluca HF. Removal of the 26-methyl group from 19-nor-1α,25-dihydroxyvitamin D3 markedly reduces in vivo calcemic activity without altering in vitro VDR binding, HL-60 cell differentiation, and transcription Journal of Medicinal Chemistry. 53: 8642-8649. PMID 21105677 DOI: 10.1021/Jm1010447  0.757
2010 Zhu J, Barycki R, Chiellini G, Deluca HF. Screening of selective inhibitors of 1α,25-Dihydroxyvitamin D 3 24-hydroxylase using recombinant human enzyme expressed in escherichia coli Biochemistry. 49: 10403-10411. PMID 21058632 DOI: 10.1021/Bi101488P  0.549
2010 Nieves NJ, Ahrens JM, Plum LA, Deluca HF, Clagett-Dame M. Identification of a unique subset of 2-methylene-19-nor analogs of vitamin D with comedolytic activity in the rhino mouse Journal of Investigative Dermatology. 130: 2359-2367. PMID 20535127 DOI: 10.1038/Jid.2010.142  0.866
2010 Schubert L, DeLuca HF. Hypophosphatemia is responsible for skeletal muscle weakness of vitamin D deficiency Archives of Biochemistry and Biophysics. 500: 157-161. PMID 20515645 DOI: 10.1016/J.Abb.2010.05.029  0.849
2010 Sibilska I, Barycka KM, Sicinski RR, Plum LA, DeLuca HF. 1-Desoxy analog of 2MD: Synthesis and biological activity of (20S)-25-hydroxy-2-methylene-19-norvitamin D3 Journal of Steroid Biochemistry and Molecular Biology. 121: 51-55. PMID 20347975 DOI: 10.1016/J.Jsbmb.2010.03.063  0.533
2010 Becklund BR, Severson KS, Vang SV, DeLuca HF. UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production. Proceedings of the National Academy of Sciences of the United States of America. 107: 6418-23. PMID 20308557 DOI: 10.1073/Pnas.1001119107  0.865
2010 Glebocka A, Sicinski RR, Plum LA, DeLuca HF. New 1α,25-dihydroxy-19-norvitamin D3 analogs with a frozen A-ring conformation Journal of Steroid Biochemistry and Molecular Biology. 121: 46-50. PMID 20214980 DOI: 10.1016/J.Jsbmb.2010.03.011  0.473
2010 Sokolowska K, Mouriño A, Sicinski RR, Sigüeiro R, Plum LA, DeLuca HF. Synthesis and biological evaluation of 6-methyl analog of 1α,25-dihydroxyvitamin D3 Journal of Steroid Biochemistry and Molecular Biology. 121: 29-33. PMID 20153829 DOI: 10.1016/J.Jsbmb.2010.02.008  0.511
2010 Wang Y, Becklund BR, DeLuca HF. Identification of a highly specific and versatile vitamin D receptor antibody Archives of Biochemistry and Biophysics. 494: 166-177. PMID 19951695 DOI: 10.1016/J.Abb.2009.11.029  0.852
2010 Zull JE, Czarnowska-Misztal E, Deluca HF. Actinomycin D Inhibition of Vitamin D Action. Science (New York, N.Y.). 149: 182-4. PMID 17734499 DOI: 10.1126/Science.149.3680.182  0.615
2010 Eguchi T, Takatsuto S, Ishiguro M, Ikekawa N, Tanaka Y, Deluca HF. Synthesis and determination of configuration of natural 25-hydroxyvitamin D(3) 26,23-lactone. Proceedings of the National Academy of Sciences of the United States of America. 78: 6579-83. PMID 16593112 DOI: 10.1073/Pnas.78.11.6579  0.627
2010 Becklund BR, Severson KS, Vang SV, DeLuca HF. Reply to Handunnetthi and Ramagopalan: UV radiation, experimental autoimmune encephalomyelitis, and multiple sclerosis Proceedings of the National Academy of Sciences of the United States of America. 107: E131. DOI: 10.1073/Pnas.1008059107  0.77
2010 YAMAMOTO K, SUN WY, OHTA M, HAMADA K, DELUCA HF, YAMADA S. ChemInform Abstract: Conformationally Restricted Analogues of 1α,25-Dihydroxyvitamin D3 and Its 20-Epimer: Compounds for Study of the Three-Dimensional Structure of Vitamin D Responsible for Binding to the Receptor. Cheminform. 27: no-no. DOI: 10.1002/chin.199643230  0.474
2010 SICINSKI RR, DELUCA HF. ChemInform Abstract: Synthesis of 6,7-Diaza-19-norvitamin D Compounds. Cheminform. 26: no-no. DOI: 10.1002/chin.199534258  0.344
2010 SICINSKI RR, DELUCA HF. ChemInform Abstract: Ruthenium Tetroxide Oxidation of Grundmann′s Ketone Derived from Vitamin D3. Cheminform. 26: no-no. DOI: 10.1002/chin.199524257  0.445
2010 PERLMAN KL, DARWISH HM, DELUCA HF. ChemInform Abstract: 20-Oxopregnacalciferols: Vitamin D Compounds That Bind the Progesterone Receptor. Cheminform. 25: no-no. DOI: 10.1002/chin.199432237  0.436
2010 YAMAMOTO K, TAKAHASHI J, HAMANO K, YAMADA S, YAMAGUCHI K, DELUCA HF. ChemInform Abstract: Stereoselective Syntheses of (22R)- and (22S)-22-Methyl-1α,25- dihydroxyvitamin D3: Active Vitamin D3 Analogs with Restricted Side Chain Conformation. Cheminform. 24: no-no. DOI: 10.1002/chin.199331269  0.444
2009 DeLuca HF. Vitamin D and the Parenteral Nutrition Patient Gastroenterology. 137: S79-S91. PMID 19874954 DOI: 10.1053/J.Gastro.2009.07.075  0.615
2009 Barycki R, Sicinski RR, Plum LA, Grzywacz P, Clagett-Dame M, DeLuca HF. Removal of the 20-methyl group from 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3 (2MD) selectively eliminates bone calcium mobilization activity Bioorganic and Medicinal Chemistry. 17: 7658-7669. PMID 19819702 DOI: 10.1016/J.Bmc.2009.09.047  0.754
2009 Becklund BR, James BJ, Gagel RF, DeLuca HF. The calcitonin/calcitonin gene related peptide-α gene is not required for 1α,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis Archives of Biochemistry and Biophysics. 488: 105-108. PMID 19563774 DOI: 10.1016/J.Abb.2009.06.015  0.845
2009 Glebocka A, Sokolowska K, Sicinski RR, Plum LA, DeLuca HF. New 1α,25-dihydroxy-19-norvitamin D3 compounds constrained in a single A-ring conformation: Synthesis of the analogues by ring-closing metathesis route and their biological evaluation Journal of Medicinal Chemistry. 52: 3496-3504. PMID 19402630 DOI: 10.1021/Jm9001583  0.458
2009 Becklund BR, Hansen DW, DeLuca HF. Enhancement of 1,25-dihydroxyvitamin D 3-mediated suppression of experimental autoimmune encephalomyelitis by calcitonin Proceedings of the National Academy of Sciences of the United States of America. 106: 5276-5281. PMID 19282478 DOI: 10.1073/Pnas.0813312106  0.848
2009 Plonska-Ocypa K, Sicinski RR, Plum LA, Grzywacz P, Frelek J, Clagett-Dame M, DeLuca HF. 13-Methyl-substituted des-C,D analogs of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): Synthesis and biological evaluation Bioorganic and Medicinal Chemistry. 17: 1747-1763. PMID 19167893 DOI: 10.1016/J.Bmc.2008.11.082  0.765
2009 Williams KB, Barycka K, Zella JB, DeLuca HF. Diaminobutane (DAB) dendrimers are potent binders of oral phosphate Journal of Bone and Mineral Research. 24: 97-101. PMID 18715138 DOI: 10.1359/Jbmr.080819  0.786
2009 Plum LA, DeLuca HF. The functional metabolism and molecular biology of vitamin D action Clinical Reviews in Bone and Mineral Metabolism. 7: 20-41. DOI: 10.1007/S12018-009-9040-Z  0.582
2008 Kutuzova GD, Sundersingh F, Vaughan J, Tadi BP, Ansay SE, Christakos S, Deluca HF. TRPV6 is not required for 1alpha,25-dihydroxyvitamin D3-induced intestinal calcium absorption in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 19655-9. PMID 19073913 DOI: 10.1073/Pnas.0810761105  0.569
2008 DeLuca HF. Evolution of our understanding of vitamin D Nutrition Reviews. 66: S73-S87. PMID 18844850 DOI: 10.1111/J.1753-4887.2008.00105.X  0.562
2008 James P, Rosenberg I, Mangelsdorf D, DeLuca H, Mathieu C, Prentice A, Meyer H, Heaney R, Holick M, Garza C, Moan JE, Angelin B, Pedersen J, Moskilde L, Cross H, et al. 22nd Marabou Symposium: the changing faces of vitamin D Nutrition Reviews. 66: 286-290. PMID 18844848 DOI: 10.1111/J.1753-4887.2008.00091.X  0.604
2008 Chiellini G, Grzywacz P, Plum LA, Barycki R, Clagett-Dame M, DeLuca HF. Synthesis and biological properties of 2-methylene-19-nor-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactones--weak agonists. Bioorganic & Medicinal Chemistry. 16: 8563-73. PMID 18722130 DOI: 10.1016/J.Bmc.2008.08.011  0.708
2008 Nakabayashi M, Yamada S, Yoshimoto N, Tanaka T, Igarashi M, Ikura T, Ito N, Makishima M, Tokiwa H, DeLuca HF, Shimizu M. Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: Structural basis for vitamin D receptor antagonism and partial agonism Journal of Medicinal Chemistry. 51: 5320-5329. PMID 18710208 DOI: 10.1021/Jm8004477  0.448
2008 Williams KB, DeLuca HF. 2-Methylene-19-nor-20(S)-1α-hydroxy-bishomopregnacalciferol [20(S)-2MbisP], an analog of vitamin D3 [1,25(OH)2D3], does not stimulate intestinal phosphate absorption at levels previously shown to suppress parathyroid hormone Steroids. 73: 1277-1284. PMID 18616960 DOI: 10.1016/J.Steroids.2008.06.003  0.752
2008 Shimizu M, Miyamoto Y, Takaku H, Matsuo M, Nakabayashi M, Masuno H, Udagawa N, DeLuca HF, Ikura T, Ito N. 2-Substituted-16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure Bioorganic and Medicinal Chemistry. 16: 6949-6964. PMID 18539034 DOI: 10.1016/J.Bmc.2008.05.043  0.391
2008 Liu N, Nguyen L, Chun RF, Lagishetty V, Ren S, Wu S, Hollis B, DeLuca HF, Adams JS, Hewison M. Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation Endocrinology. 149: 4799-4808. PMID 18535110 DOI: 10.1210/En.2008-0060  0.508
2008 Takaku H, Miyamoto Y, Asami S, Shimazaki M, Yamada S, Yamamoto K, Udagawa N, DeLuca HF, Shimizu M. Synthesis and structure-activity relationships of 16-ene-22-thia-1α,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes Bioorganic and Medicinal Chemistry. 16: 1796-1815. PMID 18032055 DOI: 10.1016/J.Bmc.2007.11.013  0.513
2007 Sicinski RR, Glebocka A, Plum LA, DeLuca HF. Design, synthesis, and biological evaluation of a 1α,25-dihydroxy-19- norvitamin D3 analogue with a frozen A-ring conformation Journal of Medicinal Chemistry. 50: 6154-6164. PMID 17960924 DOI: 10.1021/Jm070635+  0.483
2007 Schwinn MK, DeLuca HF. Differential recruitment of coactivators to the vitamin D receptor transcriptional complex by 1α,25-dihydroxyvitamin D3 analogs Archives of Biochemistry and Biophysics. 465: 443-451. PMID 17658451 DOI: 10.1016/J.Abb.2007.06.015  0.825
2007 Nehring JA, Zierold C, DeLuca HF. Lithocholic acid can carry out in vivo functions of vitamin D Proceedings of the National Academy of Sciences of the United States of America. 104: 10006-10009. PMID 17535892 DOI: 10.1073/Pnas.0703512104  0.627
2007 Slatopolsky E, Finch JL, Brown AJ, Ritter CS, Mizobuchi M, Plum LA, Clagett-Dame M, Sicinski RR, DeLuca HF. Effect of 2-methylene-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol (2MbisP), an analog of vitamin D, on secondary hyperparathyroidism Journal of Bone and Mineral Research. 22: 686-694. PMID 17444814 DOI: 10.1359/Jbmr.070202  0.776
2007 Williams KB, DeLuca HF. Characterization of intestinal phosphate absorption using a novel in vivo method American Journal of Physiology - Endocrinology and Metabolism. 292: E1917-E1921. PMID 17299082 DOI: 10.1152/Ajpendo.00654.2006  0.675
2007 Yamamoto K, Inaba Y, Yoshimoto N, Choi M, DeLuca HF, Yamada S. 22-Alkyl-20-epi-1α,25-dihydroxyvitamin D3 compounds of superagonistic activity: Syntheses, biological activities and interaction with the receptor Journal of Medicinal Chemistry. 50: 932-939. PMID 17298045 DOI: 10.1021/Jm060889F  0.49
2007 Thomson B, Ahrens JM, Ntambi JM, DeLuca HF, Clagett-Dame M. 2-Methylene-19-nor-1α-hydroxyvitamin D3 analogs inhibit adipocyte differentiation and PPARγ2 gene transcription Archives of Biochemistry and Biophysics. 460: 192-201. PMID 17257576 DOI: 10.1016/J.Abb.2006.12.020  0.773
2007 DeLuca HF, Plum LA, Clagett-Dame M. Selective analogs of 1α,25-dihydroxyvitamin D3 for the study of specific functions of Vitamin D Journal of Steroid Biochemistry and Molecular Biology. 103: 263-268. PMID 17241781 DOI: 10.1016/J.Jsbmb.2006.12.005  0.745
2007 Vanhooke JL, Tadi BP, Benning MM, Plum LA, DeLuca HF. New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: Evaluation of biological activity and structural determination of VDR-bound conformations Archives of Biochemistry and Biophysics. 460: 161-165. PMID 17227670 DOI: 10.1016/J.Abb.2006.11.029  0.444
2007 Akhter S, Kutuzova GD, Christakos S, DeLuca HF. Calbindin D9k is not required for 1,25-dihydroxyvitamin D3-mediated Ca2+ absorption in small intestine Archives of Biochemistry and Biophysics. 460: 227-232. PMID 17224126 DOI: 10.1016/J.Abb.2006.12.005  0.557
2007 Zierold C, Nehring JA, Deluca HF. Nuclear receptor 4A2 and C/EBPβ regulate the parathyroid hormone-mediated transcriptional regulation of the 25-hydroxyvitamin D3-1α-hydroxylase Archives of Biochemistry and Biophysics. 460: 233-239. PMID 17224121 DOI: 10.1016/J.Abb.2006.11.028  0.405
2007 Sicinski RR, Glebocka A, Plum LA, DeLuca HF. An analog of 1α,25-dihydroxy-19-norvitamin D3 with the 1α-hydroxy group fixed in the axial position lacks biological activity in vitro Journal of Steroid Biochemistry and Molecular Biology. 103: 293-297. PMID 17223547 DOI: 10.1016/j.jsbmb.2006.12.064  0.439
2007 Plonska-Ocypa K, Grzywacz P, Sicinski RR, Plum LA, DeLuca HF. Synthesis and biological evaluation of a des-C,D-analog of 2-methylene-19-nor-1α,25-(OH)2D3 Journal of Steroid Biochemistry and Molecular Biology. 103: 298-304. PMID 17223343 DOI: 10.1016/J.Jsbmb.2006.12.015  0.614
2007 Glebocka A, Sicinski RR, Plum LA, DeLuca HF. 2-(3′-Hydroxypropylidene)-1α-hydroxy-19-norvitamin D compounds with truncated side chains Journal of Steroid Biochemistry and Molecular Biology. 103: 310-315. PMID 17223340 DOI: 10.1016/j.jsbmb.2006.12.017  0.479
2007 Igarashi M, Yoshimoto N, Yamamoto K, Shimizu M, Ishizawa M, Makishima M, DeLuca HF, Yamada S. Identification of a highly potent vitamin D receptor antagonist: (25S)-26-Adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3) Archives of Biochemistry and Biophysics. 460: 240-253. PMID 17214957 DOI: 10.1016/J.Abb.2006.11.026  0.586
2007 Kutuzova GD, DeLuca HF. 1,25-Dihydroxyvitamin D3 regulates genes responsible for detoxification in intestine Toxicology and Applied Pharmacology. 218: 37-44. PMID 17123563 DOI: 10.1016/J.Taap.2006.10.005  0.586
2007 Kobayashi E, Shimazaki M, Miyamoto Y, Masuno H, Yamamoto K, DeLuca HF, Yamada S, Shimizu M. Structure-activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position Bioorganic and Medicinal Chemistry. 15: 1475-1482. PMID 17110116 DOI: 10.1016/J.Bmc.2006.10.069  0.516
2007 Grzywacz P, Plum LA, Sicinski RR, Clagett-Dame M, DeLuca HF. Methyl substitution of the 25-hydroxy group on 2-methylene-19-nor-1α,25-dihydroxyvitamin D3 (2MD) reduces potency but allows bone selectivity Archives of Biochemistry and Biophysics. 460: 274-284. PMID 17094936 DOI: 10.1016/J.Abb.2006.09.028  0.696
2007 Sato M, Nakamichi Y, Nakamura M, Sato N, Ninomiya T, Muto A, Nakamura H, Ozawa H, Iwasaki Y, Kobayashi E, Shimizu M, DeLuca HF, Takahashi N, Udagawa N. New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro. Bone. 40: 293-304. PMID 17070129 DOI: 10.1016/J.Bone.2006.09.007  0.534
2007 DeLuca HF. Special issue on vitamin D Archives of Biochemistry and Biophysics. 460: 151. DOI: 10.1016/J.Abb.2007.03.009  0.6
2006 Kutuzova GD, Akhter S, Christakos S, Vanhooke J, Kimmel-Jehan C, DeLuca HF. Calbindin D9k knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level Proceedings of the National Academy of Sciences of the United States of America. 103: 12377-12381. PMID 16895982 DOI: 10.1073/Pnas.0605252103  0.428
2006 Zile M, Deluca HF. A biologically active metabolite of retinoic acid from rat liver. The Biochemical Journal. 97: 180-6. PMID 16749101 DOI: 10.1042/Bj0970180  0.344
2006 Glebocka A, Sicinski RR, Plum LA, Clagett-Dame M, DeLuca HF. New 2-alkylidene 1α,25-dihydroxy-19-norvitamin D3 analogues of high intestinal activity: Synthesis and biological evaluation of 2-(3′-alkoxypropylidene) and 2-(3′-hydroxypropylidene) derivatives Journal of Medicinal Chemistry. 49: 2909-2920. PMID 16686534 DOI: 10.1021/Jm051082A  0.743
2006 Plum LA, Fitzpatrick LA, Ma X, Binkley NC, Zella JB, Clagett-Dame M, DeLuca HF. 2MD, a new anabolic agent for osteoporosis treatment Osteoporosis International. 17: 704-715. PMID 16491322 DOI: 10.1007/S00198-005-0036-3  0.808
2006 Zierold C, Mings JA, DeLuca HF. 19nor-1,25-dihydroxyvitamin D 2 specifically induces CYP3A9 in rat intestine more strongly than 1,25-dihydroxyvitamin D 3 in vivo and in vitro Molecular Pharmacology. 69: 1740-1747. PMID 16484501 DOI: 10.1124/Mol.105.019851  0.61
2006 Vanhooke JL, Prahl JM, Kimmel-Jehan C, Mendelsohn M, Danielson EW, Healy KD, DeLuca HF. CYP27B1 null mice with LacZ reporter gene display no 25-hydroxyvitamin D3-1α-hydroxylase promoter activity in the skin Proceedings of the National Academy of Sciences of the United States of America. 103: 75-80. PMID 16371465 DOI: 10.1073/Pnas.0509734103  0.82
2006 Masuno H, Morizono D, Ikura T, Ito N, DeLuca H, Tamamura H, Shimizu M. 2P032 Crystal structures of vitamin D receptor in complex with lithocholic acid derivatives(29. Protein structure and dynamics (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) Seibutsu Butsuri. 46: S303. DOI: 10.2142/Biophys.46.S303_4  0.405
2005 Meehan TF, Vanhooke J, Prahl J, Deluca HF. Hypercalcemia produced by parathyroid hormone suppresses experimental autoimmune encephalomyelitis in female but not male mice. Archives of Biochemistry and Biophysics. 442: 214-21. PMID 16183034 DOI: 10.1016/J.Abb.2005.08.011  0.771
2005 Ke HZ, Qi H, Crawford DT, Simmons HA, Xu G, Li M, Plum L, Clagett-Dame M, DeLuca HF, Thompson DD, Brown TA. A new vitamin D analog, 2MD, restores trabecular and cortical bone mass and strength in ovariectomized rats with established osteopenia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1742-55. PMID 16160732 DOI: 10.1359/Jbmr.050605  0.683
2005 Sicinska W, Westler WM, DeLuca HF. NMR assignments of tryptophan residue in apo and holo LBD-rVDR. Proteins. 61: 461-7. PMID 16130132 DOI: 10.1002/Prot.20625  0.446
2005 Albert DM, Plum LA, Yang W, Marcet M, Lindstrom MJ, Clagett-Dame M, DeLuca HF. Responsiveness of human retinoblastoma and neuroblastoma models to a non-calcemic 19-nor Vitamin D analog. The Journal of Steroid Biochemistry and Molecular Biology. 97: 165-72. PMID 16055326 DOI: 10.1016/J.Jsbmb.2005.06.019  0.719
2005 Rohde CM, DeLuca HF. All-trans retinoic acid antagonizes the action of calciferol and its active metabolite, 1,25-dihydroxycholecalciferol, in rats. The Journal of Nutrition. 135: 1647-52. PMID 15987844 DOI: 10.1093/Jn/135.7.1647  0.85
2005 Healy KD, Vanhooke JL, Prahl JM, DeLuca HF. Parathyroid hormone decreases renal vitamin D receptor expression in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 4724-8. PMID 15769857 DOI: 10.1073/Pnas.0501312102  0.838
2005 Karnauskas AJ, van Leeuwen JP, van den Bemd GJ, Kathpalia PP, DeLuca HF, Bushinsky DA, Favus MJ. Mechanism and function of high vitamin D receptor levels in genetic hypercalciuric stone-forming rats. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 447-54. PMID 15746989 DOI: 10.1359/Jbmr.041120  0.424
2005 Healy KD, Frahm MA, DeLuca HF. 1,25-Dihydroxyvitamin D3 up-regulates the renal vitamin D receptor through indirect gene activation and receptor stabilization. Archives of Biochemistry and Biophysics. 433: 466-73. PMID 15581603 DOI: 10.1016/J.Abb.2004.10.001  0.826
2005 DeLuca HF, Plum LA, Clagett-Dame M, Shevde NK, Wesley Pike J, Sicinski RR. 2-Carbon-Modified Analogs of 19-Nor-1α,25-Dihydroxyvitamin D3 Vitamin D. 2: 1543-1555. DOI: 10.1016/B978-012252687-9/50091-7  0.656
2004 DeLuca HF. Overview of general physiologic features and functions of vitamin D. The American Journal of Clinical Nutrition. 80: 1689S-96S. PMID 15585789 DOI: 10.1093/Ajcn/80.6.1689S  0.618
2004 Kutuzova GD, Deluca HF. Gene expression profiles in rat intestine identify pathways for 1,25-dihydroxyvitamin D(3) stimulated calcium absorption and clarify its immunomodulatory properties. Archives of Biochemistry and Biophysics. 432: 152-66. PMID 15542054 DOI: 10.1016/J.Abb.2004.09.004  0.581
2004 Binkley N, Krueger D, Cowgill CS, Plum L, Lake E, Hansen KE, DeLuca HF, Drezner MK. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. The Journal of Clinical Endocrinology and Metabolism. 89: 3152-7. PMID 15240586 DOI: 10.1210/Jc.2003-031979  0.478
2004 Sicinska W, Rotkiewicz P, DeLuca HF. Model of three-dimensional structure of VDR bound with Vitamin D3 analogs substituted at carbon-2. The Journal of Steroid Biochemistry and Molecular Biology. 89: 107-10. PMID 15225755 DOI: 10.1016/J.Jsbmb.2004.03.102  0.523
2004 DeLuca HF. Therapeutic potential of the 2-alkyl and 2-alkylidene-19-nor-(20S)-modified analogs of 1alpha,25-dihydroxyvitamin D3. The Journal of Steroid Biochemistry and Molecular Biology. 89: 67-73. PMID 15225749 DOI: 10.1016/J.Jsbmb.2004.03.104  0.441
2004 Glebocka A, Sicinski RR, DeLuca HF. New derivative of 1alpha,25-dihydroxy-19-norvitamin D3 with 3'-alkoxypropylidene moiety at C-2: synthesis, biological activity and conformational analysis. The Journal of Steroid Biochemistry and Molecular Biology. 89: 25-30. PMID 15225741 DOI: 10.1016/J.Jsbmb.2004.03.105  0.57
2004 Grzywacz P, Plum LA, Sicinska W, Sicinski RR, Prahl JM, DeLuca HF. 2-Methylene analogs of 1alpha-hydroxy-19-norvitamin D3: synthesis, biological activities and docking to the ligand binding domain of the rat vitamin D receptor. The Journal of Steroid Biochemistry and Molecular Biology. 89: 13-7. PMID 15225739 DOI: 10.1016/J.Jsbmb.2004.03.103  0.615
2004 Plum LA, Prahl JM, Ma X, Sicinski RR, Gowlugari S, Clagett-Dame M, DeLuca HF. Biologically active noncalcemic analogs of 1alpha,25-dihydroxyvitamin D with an abbreviated side chain containing no hydroxyl. Proceedings of the National Academy of Sciences of the United States of America. 101: 6900-4. PMID 15118084 DOI: 10.1073/Pnas.0401656101  0.777
2004 Vanhooke JL, Benning MM, Bauer CB, Pike JW, DeLuca HF. Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide. Biochemistry. 43: 4101-10. PMID 15065852 DOI: 10.1021/Bi036056Y  0.426
2004 DeLuca HF. The Vitamin D System: Receptor, Analogs and Functions Gbm Annual Spring Meeting Mosbach 2004. 2004. DOI: 10.1240/sav_gbm_2004_m_000452  0.474
2003 Goldstein JT, Dobrzyn A, Clagett-Dame M, Pike JW, DeLuca HF. Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor. Archives of Biochemistry and Biophysics. 420: 185-93. PMID 14622989 DOI: 10.1016/J.Abb.2003.09.034  0.725
2003 Zella JB, McCary LC, DeLuca HF. Oral administration of 1,25-dihydroxyvitamin D3 completely protects NOD mice from insulin-dependent diabetes mellitus. Archives of Biochemistry and Biophysics. 417: 77-80. PMID 12921782 DOI: 10.1016/S0003-9861(03)00338-2  0.842
2003 Healy KD, Zella JB, Prahl JM, DeLuca HF. Regulation of the murine renal vitamin D receptor by 1,25-dihydroxyvitamin D3 and calcium. Proceedings of the National Academy of Sciences of the United States of America. 100: 9733-7. PMID 12900504 DOI: 10.1073/Pnas.1633774100  0.868
2003 Yamamoto H, Shevde NK, Warrier A, Plum LA, DeLuca HF, Pike JW. 2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts. The Journal of Biological Chemistry. 278: 31756-65. PMID 12796488 DOI: 10.1074/Jbc.M304737200  0.577
2003 Tryfonidou MA, Holl MS, Stevenhagen JJ, Buurman CJ, Deluca HF, Oosterlaken-Dijksterhuis MA, van den Brom WE, van Leeuwen JP, Hazewinkel HA. Dietary 135-fold cholecalciferol supplementation severely disturbs the endochondral ossification in growing dogs. Domestic Animal Endocrinology. 24: 265-85. PMID 12742547 DOI: 10.1016/S0739-7240(03)00018-3  0.601
2003 Choi M, Yamamoto K, Itoh T, Makishima M, Mangelsdorf DJ, Moras D, DeLuca HF, Yamada S. Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis. Chemistry & Biology. 10: 261-70. PMID 12670540 DOI: 10.1016/S1074-5521(03)00050-4  0.491
2003 Shimizu M, Iwasaki Y, Shibamoto Y, Sato M, DeLuca HF, Yamada S. Novel synthesis of 2-substituted 19-norvitamin D A-ring phosphine oxide from D-glucose as a building block. Bioorganic & Medicinal Chemistry Letters. 13: 809-12. PMID 12617896 DOI: 10.1016/S0960-894X(03)00005-2  0.41
2003 Rohde CM, DeLuca H. Bone resorption activity of all-trans retinoic acid is independent of vitamin D in rats. The Journal of Nutrition. 133: 777-83. PMID 12612152 DOI: 10.1093/Jn/133.3.777  0.84
2003 Zierold C, Mings JA, DeLuca HF. Regulation of 25-hydroxyvitamin D3-24-hydroxylase mRNA by 1,25-dihydroxyvitamin D3 and parathyroid hormone. Journal of Cellular Biochemistry. 88: 234-7. PMID 12520520 DOI: 10.1002/Jcb.10341  0.539
2003 Zella JB, DeLuca HF. Vitamin D and autoimmune diabetes. Journal of Cellular Biochemistry. 88: 216-22. PMID 12520517 DOI: 10.1002/Jcb.10347  0.85
2003 Tryfonidou MA, Stevenhagen JJ, van den Bemd GJ, Oosterlaken-Dijksterhuis MA, DeLuca HF, Mol JA, van den Brom WE, van Leeuwen JP, Hazewinkel HA. Moderate cholecalciferol supplementation depresses intestinal calcium absorption in growing dogs. The Journal of Nutrition. 132: 2644-50. PMID 12221224 DOI: 10.1093/Jn/132.9.2644  0.558
2003 Shimizu M, Iwasaki Y, Shibamoto Y, Sato M, DeLuca HF, Yamada S. Novel Synthesis of 2-Substituted 19-Norvitamin D A-Ring Phosphine Oxide from D-Glucose as a Building Block. Cheminform. 34. DOI: 10.1002/chin.200330235  0.357
2002 Meehan TF, DeLuca HF. The vitamin D receptor is necessary for 1alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice. Archives of Biochemistry and Biophysics. 408: 200-4. PMID 12464272 DOI: 10.1016/S0003-9861(02)00580-5  0.803
2002 Becker BN, Hullett DA, O'herrin JK, Malin G, Sollinger HW, Deluca H. Vitamin D as immunomodulatory therapy for kidney transplantation. Transplantation. 74: 1204-1206. PMID 12438976 DOI: 10.1097/00007890-200210270-00030  0.507
2002 Song J, Clagett-Dame M, Peterson RE, Hahn ME, Westler WM, Sicinski RR, DeLuca HF. A ligand for the aryl hydrocarbon receptor isolated from lung. Proceedings of the National Academy of Sciences of the United States of America. 99: 14694-9. PMID 12409613 DOI: 10.1073/Pnas.232562899  0.596
2002 Shevde NK, Plum LA, Clagett-Dame M, Yamamoto H, Pike JW, DeLuca HF. A potent analog of 1alpha,25-dihydroxyvitamin D3 selectively induces bone formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 13487-91. PMID 12374862 DOI: 10.1073/Pnas.202471299  0.715
2002 Johnson LE, DeLuca HF. Reproductive defects are corrected in vitamin d-deficient female rats fed a high calcium, phosphorus and lactose diet. The Journal of Nutrition. 132: 2270-3. PMID 12163674 DOI: 10.1093/Jn/132.8.2270  0.606
2002 Sicinski RR, Rotkiewicz P, Kolinski A, Sicinska W, Prahl JM, Smith CM, DeLuca HF. 2-Ethyl and 2-ethylidene analogues of 1alpha,25-dihydroxy-19-norvitamin D(3): synthesis, conformational analysis, biological activities, and docking to the modeled rVDR ligand binding domain. Journal of Medicinal Chemistry. 45: 3366-80. PMID 12139448 DOI: 10.1021/Jm020007M  0.531
2002 Zierold C, Mings JA, Prahl JM, Reinholz GG, DeLuca HF. Protein synthesis is required for optimal induction of 25-hydroxyvitamin D(3)-24-hydroxylase, osteocalcin, and osteopontin mRNA by 1,25-dihydroxyvitamin D(3). Archives of Biochemistry and Biophysics. 404: 18-24. PMID 12127065 DOI: 10.1016/S0003-9861(02)00238-2  0.545
2002 Ogunkolade BW, Boucher BJ, Prahl JM, Bustin SA, Burrin JM, Noonan K, North BV, Mannan N, McDermott MF, DeLuca HF, Hitman GA. Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians. Diabetes. 51: 2294-300. PMID 12086963 DOI: 10.2337/Diabetes.51.7.2294  0.357
2002 Clagett-Dame M, DeLuca HF. The role of vitamin A in mammalian reproduction and embryonic development. Annual Review of Nutrition. 22: 347-81. PMID 12055350 DOI: 10.1146/Annurev.Nutr.22.010402.102745E  0.697
2002 Beckman MJ, DeLuca HF. Regulation of renal vitamin D receptor is an important determinant of 1alpha,25-dihydroxyvitamin D(3) levels in vivo. Archives of Biochemistry and Biophysics. 401: 44-52. PMID 12054486 DOI: 10.1016/S0003-9861(02)00010-3  0.625
2002 Qi X, Pramanik R, Wang J, Schultz RM, Maitra RK, Han J, Deluca HF, Chen G. The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D3-induced growth inhibition Journal of Biological Chemistry. 277: 25884-25892. PMID 11983707 DOI: 10.1074/Jbc.M203039200  0.489
2002 Meehan TF, DeLuca HF. CD8(+) T cells are not necessary for 1 alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 5557-60. PMID 11929984 DOI: 10.1073/Pnas.082100699  0.743
2002 Sicinski RR, Prahl JM, Smith CM, DeLuca HF. New highly calcemic 1 alpha,25-dihydroxy-19-norvitamin D(3) compounds with modified side chain: 26,27-dihomo- and 26,27-dimethylene analogs in 20S-series. Steroids. 67: 247-56. PMID 11856548 DOI: 10.1016/S0039-128X(01)00156-8  0.53
2002 Werner EA, Deluca HF. Retinoic acid is detected at relatively high levels in the CNS of adult rats. American Journal of Physiology. Endocrinology and Metabolism. 282: E672-8. PMID 11832372 DOI: 10.1152/Ajpendo.00280.2001  0.574
2002 Deluca HF, Cantorna MT. Vitamin D: its role and uses in immunology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2579-85. PMID 11726533 DOI: 10.1096/Fj.01-0433Rev  0.576
2001 Zierold C, Mings JA, DeLuca HF. Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability. Proceedings of the National Academy of Sciences of the United States of America. 98: 13572-6. PMID 11698670 DOI: 10.1073/Pnas.241516798  0.509
2001 Werner EA, DeLuca HF. Metabolism of a physiological amount of all-trans-retinol in the vitamin A-deficient rat. Archives of Biochemistry and Biophysics. 393: 262-70. PMID 11556813 DOI: 10.1006/Abbi.2001.2495  0.657
2001 Rotkiewicz P, Sicinska W, Kolinski A, DeLuca HF. Model of three-dimensional structure of vitamin D receptor and its binding mechanism with 1alpha,25-dihydroxyvitamin D(3). Proteins. 44: 188-99. PMID 11455592 DOI: 10.1002/Prot.1084  0.45
2001 Johnson LE, DeLuca HF. Vitamin D receptor null mutant mice fed high levels of calcium are fertile. The Journal of Nutrition. 131: 1787-91. PMID 11385068 DOI: 10.1093/Jn/131.6.1787  0.383
2001 Endres B, DeLuca HF. 26-Hydroxylation of 1alpha,25-dihydroxyvitamin D3 does not occur under physiological conditions. Archives of Biochemistry and Biophysics. 388: 127-34. PMID 11361128 DOI: 10.1006/Abbi.2000.2271  0.535
2001 Brenza HL, DeLuca HF. Analysis of basal regulatory elements in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene promoter. Archives of Biochemistry and Biophysics. 388: 121-6. PMID 11361127 DOI: 10.1006/Abbi.2001.2279  0.778
2001 Takayama H, Konno K, Fujishima T, Maki S, Liu Z, Miura D, Chokki M, Ishizuka S, Smith C, DeLuca HF, Nakagawa K, Kurobe M, Okano T. Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1α, 25-dihydroxyvitamin D3 and 20-epi-2-methyl-1α, 25-dihydroxyvitamin D3 Steroids. 66: 277-285. PMID 11179735 DOI: 10.1016/S0039-128X(00)00141-0  0.425
2001 Maurer U, Jehan F, Englert C, Hubinger G, Weidmann E, DeLuca HF, Bergmann L. The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor. The Journal of Biological Chemistry. 276: 3727-32. PMID 11050081 DOI: 10.1074/Jbc.M005292200  0.5
2000 Reichrath J, Classen UG, Meineke V, DeLuca H, Tilgen W, Kerber A, Holick MF. Immunoreactivity of six monoclonal antibodies directed against 1,25-dihydroxyvitamin-D3 receptors in human skin. Histochemical Journal. 32: 625-629. PMID 11202159 DOI: 10.1023/A:1026748824945  0.335
2000 Konno K, Fujishima T, Maki S, Liu Z, Miura D, Chokki M, Ishizuka S, Yamaguchi K, Kan Y, Kurihara M, Miyata N, Smith C, DeLuca HF, Takayama H. Synthesis, biological evaluation, and conformational analysis of A-ring diastereomers of 2-methyl-1,25-dihydroxyvitamin D(3) and their 20-epimers: unique activity profiles depending on the stereochemistry of the A-ring and at C-20. Journal of Medicinal Chemistry. 43: 4247-65. PMID 11063621 DOI: 10.1021/Jm000261J  0.381
2000 Zierold C, Reinholz GG, Mings JA, Prahl JM, DeLuca HF. Regulation of the procine 1,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 and parathyroid hormone in AOK-B50 cells. Archives of Biochemistry and Biophysics. 381: 323-7. PMID 11032422 DOI: 10.1006/Abbi.2000.1964  0.57
2000 Brenza HL, DeLuca HF. Regulation of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression by parathyroid hormone and 1,25-dihydroxyvitamin D3. Archives of Biochemistry and Biophysics. 381: 143-52. PMID 11019830 DOI: 10.1006/Abbi.2000.1970  0.85
2000 Jehan F, DeLuca HF. The mouse vitamin D receptor is mainly expressed through an Sp1-driven promoter in vivo. Archives of Biochemistry and Biophysics. 377: 273-83. PMID 10845704 DOI: 10.1006/Abbi.2000.1788  0.301
2000 Kimmel-Jehan C, DeLuca HF. Cloning of the mouse 25-hydroxyvitamin D(3)-1alpha-hydroxylase (CYP1alpha) gene. Biochimica Et Biophysica Acta. 1475: 109-13. PMID 10832023 DOI: 10.1016/S0304-4165(00)00065-9  0.421
2000 Cantorna MT, Humpal-Winter J, DeLuca HF. In vivo upregulation of interleukin-4 is one mechanism underlying the immunoregulatory effects of 1,25-dihydroxyvitamin D(3). Archives of Biochemistry and Biophysics. 377: 135-8. PMID 10775452 DOI: 10.1006/Abbi.2000.1765  0.523
2000 Endres B, Kato S, DeLuca HF. Metabolism of 1alpha,25-dihydroxyvitamin D(3) in vitamin D receptor-ablated mice in vivo. Biochemistry. 39: 2123-9. PMID 10684662 DOI: 10.1021/Bi9923757  0.561
2000 Lu Z, Jehan F, Zierold C, DeLuca HF. Isolation and characterization of the chicken vitamin D receptor gene and its promoter. Journal of Cellular Biochemistry. 77: 92-102. PMID 10679820 DOI: 10.1002/(Sici)1097-4644(20000401)77:1<92::Aid-Jcb10>3.0.Co;2-N  0.393
2000 van den Bemd GC, Dilworth FJ, Makin HL, Prahl JM, Deluca HF, Jones G, Pols HA, van Leeuwen JP. Contribution of several metabolites of the vitamin D analog 20-epi-22-oxa-24a,26a,27a-tri-homo-1,25-(OH)(2) vitamin D(3) (KH 1060) to the overall biological activity of KH1060 by a shared mechanism of action. Biochemical Pharmacology. 59: 621-7. PMID 10677578 DOI: 10.1016/S0006-2952(99)00371-8  0.546
2000 Yamamoto K, Masuno H, Choi M, Nakashima K, Taga T, Ooizumi H, Umesono K, Sicinska W, VanHooke J, DeLuca HF, Yamada S. Three-dimensional modeling of and ligand docking to vitamin D receptor ligand binding domain. Proceedings of the National Academy of Sciences of the United States of America. 97: 1467-72. PMID 10677485 DOI: 10.1073/Pnas.020522697  0.415
2000 Veldman CM, Cantorna MT, DeLuca HF. Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system. Archives of Biochemistry and Biophysics. 374: 334-8. PMID 10666315 DOI: 10.1006/Abbi.1999.1605  0.554
2000 Sicinski RR, DeLuca HF. Synthesis and biological activity of 22-iodo- and (E)-20(22)-dehydro analogues of 1alpha,25-dihydroxyvitamin D3. Bioorganic & Medicinal Chemistry. 7: 2877-89. PMID 10658592 DOI: 10.1016/S0968-0896(99)00249-7  0.59
2000 Jääskeläinen T, Ryhänen S, Mahonen A, DeLuca HF, Mäenpää PH. Mechanism of action of superactive vitamin D analogs through regulated receptor degradation. Journal of Cellular Biochemistry. 76: 548-58. PMID 10653974 DOI: 10.1002/(Sici)1097-4644(20000315)76:4<548::Aid-Jcb3>3.0.Co;2-0  0.472
2000 Nessel R, Hullett D, Oberley T, DeLuca H, Sollinger H. PROLONGATION OF RAT KIDNEY ALLOGRAFTS USING 1,25(OH)2D3 AS THE SOLE IMMUNOSUPPRESSIVE AGENT. Transplantation. 69: S196. DOI: 10.1097/00007890-200004271-00318  0.463
1999 Rohde CM, Manatt M, Clagett-Dame M, DeLuca HF. Vitamin A antagonizes the action of vitamin D in rats. The Journal of Nutrition. 129: 2246-50. PMID 10573558 DOI: 10.1093/Jn/129.12.2246  0.883
1999 Cantorna MT, Humpal-Winter J, DeLuca HF. Dietary calcium is a major factor in 1,25-dihydroxycholecalciferol suppression of experimental autoimmune encephalomyelitis in mice. The Journal of Nutrition. 129: 1966-71. PMID 10539770 DOI: 10.1093/Jn/129.11.1966  0.341
1999 McCary LC, Staun M, DeLuca HF. A characterization of vitamin D-independent intestinal calcium absorption in the osteopetrotic (op/op) mouse. Archives of Biochemistry and Biophysics. 368: 249-56. PMID 10441375 DOI: 10.1006/Abbi.1999.1286  0.573
1999 Kimmel-Jehan C, Darwish HM, Strugnell SA, Jehan F, Wiefling B, DeLuca HF. DNA bending is induced by binding of vitamin D receptor-retinoid X receptor heterodimers to vitamin D response elements. Journal of Cellular Biochemistry. 74: 220-8. PMID 10404392 DOI: 10.1002/(Sici)1097-4644(19990801)74:2<220::Aid-Jcb8>3.0.Co;2-T  0.558
1999 Shinki T, Ueno Y, DeLuca HF, Suda T. Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic rats. Proceedings of the National Academy of Sciences of the United States of America. 96: 8253-8. PMID 10393981 DOI: 10.1073/Pnas.96.14.8253  0.49
1999 Yamamoto K, Ooizumi H, Umesono K, Verstuyf A, Bouillon R, DeLuca HF, Shinki T, Suda T, Yamada S. Three-dimensional structure-function relationship of vitamin D: side chain location and various activities. Bioorganic & Medicinal Chemistry Letters. 9: 1041-6. PMID 10230636 DOI: 10.1016/S0960-894X(99)00129-8  0.451
1999 Darwish HM, DeLuca HF. Identification of a transcription factor that binds to the promoter region of the human parathyroid hormone gene. Archives of Biochemistry and Biophysics. 365: 123-30. PMID 10222046 DOI: 10.1006/Abbi.1999.1160  0.402
1999 Strugnell SA, Hill JJ, McCaslin DR, Wiefling BA, Royer CA, DeLuca HF. Bacterial expression and characterization of the ligand-binding domain of the vitamin D receptor. Archives of Biochemistry and Biophysics. 364: 42-52. PMID 10087163 DOI: 10.1006/Abbi.1999.9999  0.367
1999 Colin EM, Van Den Bemd GJ, Van Aken M, Christakos S, De Jonge HR, Deluca HF, Prahl JM, Birkenhäger JC, Buurman CJ, Pols HA, Van Leeuwen JP. Evidence for involvement of 17beta-estradiol in intestinal calcium absorption independent of 1,25-dihydroxyvitamin D3 level in the Rat. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 14: 57-64. PMID 9893066 DOI: 10.1359/Jbmr.1999.14.1.57  0.454
1999 Zierold C, DeLuca HF. Additional protein factors play a role in the formation of VDR/RXR complexes on vitamin D response elements. Journal of Cellular Biochemistry. 71: 515-23. PMID 9827697 DOI: 10.1002/(Sici)1097-4644(19981215)71:4<515::Aid-Jcb6>3.0.Co;2-C  0.416
1998 Kutner A, Link RP, Schnoes HK, DeLuca HF. Photoactivable analogs for labeling 25-hydroxyvitamin D3 serum binding protein and for 1,25-dihydroxyvitamin D3 intestinal receptor protein. Bioorganic Chemistry. 14: 134-47. PMID 11540940 DOI: 10.1016/0045-2068(86)90023-4  0.574
1998 Beckman MJ, Deluca HF. Modern view of vitamin D3 and its medicinal uses. Progress in Medicinal Chemistry. 35: 1-56. PMID 10795398 DOI: 10.1016/S0079-6468(08)70033-X  0.583
1998 White JC, Shankar VN, Highland M, Epstein ML, Deluca HF, Clagett-Dame M. Defects in embryonic hindbrain development and fetal resorption resulting from vitamin A deficiency in the rat are prevented by feeding pharmacological levels of all-trans-retinoic acid Proceedings of the National Academy of Sciences of the United States of America. 95: 13459-13464. PMID 9811822 DOI: 10.1073/Pnas.95.23.13459  0.628
1998 Sicinski RR, Prahl JM, Smith CM, DeLuca HF. New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues. Journal of Medicinal Chemistry. 41: 4662-74. PMID 9804706 DOI: 10.1021/Jm9802618  0.512
1998 Cantorna MT, Hullett DA, Redaelli C, Brandt CR, Humpal-Winter J, Sollinger HW, Deluca HF. 1,25-Dihydroxyvitamin D3 prolongs graft survival without compromising host resistance to infection or bone mineral density. Transplantation. 66: 828-31. PMID 9798689 DOI: 10.1097/00007890-199810150-00003  0.362
1998 Hullett DA, Cantorna MT, Redaelli C, Humpal-Winter J, Hayes CE, Sollinger HW, Deluca HF. Prolongation of allograft survival by 1,25-dihydroxyvitamin D3. Transplantation. 66: 824-8. PMID 9798688 DOI: 10.1097/00007890-199810150-00002  0.769
1998 Jones G, Strugnell SA, DeLuca HF. Current understanding of the molecular actions of vitamin D. Physiological Reviews. 78: 1193-231. PMID 9790574 DOI: 10.1152/Physrev.1998.78.4.1193  0.625
1998 Güzey M, Sattler C, DeLuca HF. Combinational effects of vitamin D3 and retinoic acid (all trans and 9 cis) on proliferation, differentiation, and programmed cell death in two small cell lung carcinoma cell lines. Biochemical and Biophysical Research Communications. 249: 735-44. PMID 9731207 DOI: 10.1006/Bbrc.1998.9186  0.438
1998 Wood RJ, Fleet JC, Cashman K, Bruns ME, Deluca HF. Intestinal calcium absorption in the aged rat: evidence of intestinal resistance to 1,25(OH)2 vitamin D. Endocrinology. 139: 3843-8. PMID 9724038 DOI: 10.1210/Endo.139.9.6176  0.603
1998 Biehl RR, Baker DH, Deluca HF. Activity of various hydroxylated vitamin D3 analogs for improving phosphorus utilisation in chicks receiving diets adequate in vitamin D3. British Poultry Science. 39: 408-12. PMID 9693823 DOI: 10.1080/00071669888971  0.567
1998 Reinholz GG, DeLuca HF. Inhibition of 25-hydroxyvitamin D3 production by 1, 25-dihydroxyvitamin D3 in rats. Archives of Biochemistry and Biophysics. 355: 77-83. PMID 9647669 DOI: 10.1006/Abbi.1998.0706  0.603
1998 DeLuca HF, Zierold C. Mechanisms and functions of vitamin D. Nutrition Reviews. 56: S4-10; discussion S . PMID 9564171 DOI: 10.1111/J.1753-4887.1998.Tb01686.X  0.578
1998 Jia X, Sicinski RR, Wellik DM, Tadikonda P, Schnoes HK, DeLuca HF. Identification of a new all-trans-retinol metabolite produced through a new retinol metabolic pathway. Biochemistry. 37: 5974-80. PMID 9558333 DOI: 10.1021/Bi972561H  0.345
1998 Jehan F, Ismail R, Hanson K, DeLuca HF. Cloning and expression of the chicken 25-hydroxyvitamin D3 24-hydroxylase cDNA. Biochimica Et Biophysica Acta. 1395: 259-65. PMID 9512657 DOI: 10.1016/S0167-4781(97)00177-2  0.523
1998 Brenza HL, Kimmel-Jehan C, Jehan F, Shinki T, Wakino S, Anazawa H, Suda T, DeLuca HF. Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter. Proceedings of the National Academy of Sciences of the United States of America. 95: 1387-91. PMID 9465024 DOI: 10.1073/Pnas.95.4.1387  0.808
1998 Arbour NC, Ross TK, Zierold C, Prahl JM, Deluca HF. A highly sensitive method for large-scale measurements of 1,25- dihydroxyvitamin D Analytical Biochemistry. 255: 148-154. PMID 9448854 DOI: 10.1006/Abio.1997.2439  0.576
1998 Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. The Journal of Nutrition. 128: 68-72. PMID 9430604 DOI: 10.1093/Jn/128.1.68  0.622
1998 McCary LC, Smith CM, DeLuca HF. Hypophosphatemia and the development of rickets in osteopetrotic (op/op) mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 12: 1944-51. PMID 9383699 DOI: 10.1359/Jbmr.1997.12.11.1944  0.444
1998 Shinki T, Shimada H, Wakino S, Anazawa H, Hayashi M, Saruta T, DeLuca HF, Suda T. Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA. Proceedings of the National Academy of Sciences of the United States of America. 94: 12920-5. PMID 9371776 DOI: 10.1073/Pnas.94.24.12920  0.53
1998 Hullett DA, Cantorna MT, Redaelli C, Brandt CR, Humpal-Winter J, Sollinger HW, DeLuca HF. 1,25-DIHYROXYVITAMIN D3-INDUCED PROLONGATION OF GRAFT SURVIVAL WITHOUT INCREASED SUSCEPTIBILITY TO OPPORTUNISTIC INFECTION MAY BE MEDIATED BY ALTERED ANTIGEN PRESENTATION Transplantation. 66: S39. DOI: 10.1097/00007890-199810270-00184  0.357
1997 Monkawa T, Yoshida T, Wakino S, Shinki T, Anazawa H, Deluca HF, Suda T, Hayashi M, Saruta T. Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1 alpha-hydroxylase. Biochemical and Biophysical Research Communications. 239: 527-33. PMID 9344864 DOI: 10.1006/Bbrc.1997.7508  0.472
1997 Beckman MJ, DeLuca HF. Assay of 25-hydroxyvitamin D 1 alpha-hydroxylase and 24-hydroxylase. Methods in Enzymology. 282: 200-13. PMID 9330289 DOI: 10.1016/S0076-6879(97)82108-8  0.569
1997 Beckman MJ, DeLuca HF. Assay of 1,25-dihydroxyvitamin D3 from serum samples: use of receptor-binding or enzyme-coupled reporter analysis. Methods in Enzymology. 282: 164-74. PMID 9330286 DOI: 10.1016/S0076-6879(97)82105-2  0.553
1997 Hayes CE, Cantorna MT, DeLuca HF. Vitamin D and multiple sclerosis. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 216: 21-7. PMID 9316607 DOI: 10.3181/00379727-216-44153A  0.745
1997 Jehan F, DeLuca HF. Cloning and characterization of the mouse vitamin D receptor promoter. Proceedings of the National Academy of Sciences of the United States of America. 94: 10138-43. PMID 9294176 DOI: 10.1073/Pnas.94.19.10138  0.465
1997 Strugnell SA, Deluca HF. The vitamin D receptor--structure and transcriptional activation. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 215: 223-8. PMID 9207856 DOI: 10.3181/00379727-215-44131  0.472
1997 Kinyamu HK, Gallagher JC, Prahl JM, DeLuca HF, Petranick KM, Lanspa SJ. Association between intestinal vitamin D receptor, calcium absorption, and serum 1,25 dihydroxyvitamin D in normal young and elderly women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 12: 922-8. PMID 9169351 DOI: 10.1359/Jbmr.1997.12.6.922  0.477
1997 Kinyamu HK, Gallagher JC, Knezetic JA, DeLuca HF, Prahl JM, Lanspa SJ. Effect of vitamin D receptor genotypes on calcium absorption, duodenal vitamin D receptor concentration, and serum 1,25 dihydroxyvitamin D levels in normal women. Calcified Tissue International. 60: 491-5. PMID 9164821 DOI: 10.1007/S002239900269  0.548
1997 DeLuca HF. Discovery of the vitamin D endocrine system. The Journal of Nutrition. 127: 1050S-1052S. PMID 9164307 DOI: 10.1093/Jn/127.5.1017S  0.54
1997 Kimmel-Jehan C, Jehan F, DeLuca HF. Salt concentration determines 1,25-dihydroxyvitamin D3 dependency of vitamin D receptor-retinoid X receptor--vitamin D-responsive element complex formation. Archives of Biochemistry and Biophysics. 341: 75-80. PMID 9143355 DOI: 10.1006/Abbi.1997.9952  0.553
1997 Lu Z, Hanson K, DeLuca HF. Cloning and origin of the two forms of chicken vitamin D receptor. Archives of Biochemistry and Biophysics. 339: 99-106. PMID 9056239 DOI: 10.1006/Abbi.1996.9864  0.372
1997 Guo B, Aslam F, Van Wijnen AJ, Roberts SGE, Frenkel B, Green MR, Deluca H, Lian JB, Stein GS, Stein JL. YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene Proceedings of the National Academy of Sciences of the United States of America. 94: 121-126. PMID 8990171 DOI: 10.1073/Pnas.94.1.121  0.529
1996 NORMAN AW, LUND J, DELUCA HF. BIOLOGICALLY ACTIVE FORMS OF VITAMIN D3 IN KIDNEY AND INTESTINE. Archives of Biochemistry and Biophysics. 108: 12-21. PMID 14233904 DOI: 10.1016/0003-9861(64)90349-2  0.593
1996 ENGSTROM GW, DELUCA HF. VITAMIN D-STIMULATED RELEASE OF CALCIUM FROM MITOCHONDRIA. Biochemistry. 3: 203-9. PMID 14163942 DOI: 10.1021/Bi00890A011  0.507
1996 Engstrom GW, Deluca HF. EFFECT OF EGG WHITE DIETS ON CALCIUM METABOLISM IN THE RAT. The Journal of Nutrition. 81: 218-22. PMID 14083235 DOI: 10.1093/Jn/81.3.218  0.306
1996 Uhland-Smith A, Prahl JM, DeLuca HF. An enzyme-linked immunoassay for the 1,25-dihydroxyvitamin D3 receptor protein. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 11: 1921-5. PMID 8970894 DOI: 10.1002/Jbmr.5650111213  0.342
1996 Staal A, van Wijnen AJ, Birkenhäger JC, Pols HA, Prahl J, DeLuca H, Gaub MP, Lian JB, Stein GS, van Leeuwen JP, Stein JL. Distinct conformations of vitamin D receptor/retinoid X receptor-alpha heterodimers are specified by dinucleotide differences in the vitamin D-responsive elements of the osteocalcin and osteopontin genes. Molecular Endocrinology (Baltimore, Md.). 10: 1444-56. PMID 8923469 DOI: 10.1210/Mend.10.11.8923469  0.34
1996 Darwish HM, DeLuca HF. Analysis of binding of the 1,25-dihydroxyvitamin D3 receptor to positive and negative vitamin D response elements. Archives of Biochemistry and Biophysics. 334: 223-34. PMID 8900396 DOI: 10.1006/Abbi.1996.0450  0.49
1996 Sicinski RR, Perlman KL, Prahl J, Smith C, DeLuca HF. Synthesis and biological activity of 1 alpha, 25-dihydroxy-18-norvitamin D3 and 1 alpha, 25-dihydroxy-18,19-dinorvitamin D3. Journal of Medicinal Chemistry. 39: 4497-506. PMID 8893845 DOI: 10.1021/Jm950745T  0.539
1996 Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 93: 7861-4. PMID 8755567 DOI: 10.1073/Pnas.93.15.7861  0.759
1996 Yamamoto K, Sun WY, Ohta M, Hamada K, DeLuca HF, Yamada S. Conformationally restricted analogs of 1 alpha, 25-dihydroxyvitamin D3 and its 20-epimer: compounds for study of the three-dimensional structure of vitamin D responsible for binding to the receptor. Journal of Medicinal Chemistry. 39: 2727-37. PMID 8709103 DOI: 10.1021/Jm9600048  0.582
1996 Beckman MJ, Tadikonda P, Werner E, Prahl J, Yamada S, DeLuca HF. Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme. Biochemistry. 35: 8465-72. PMID 8679605 DOI: 10.1021/Bi960658I  0.752
1996 Wellik DM, DeLuca HF. Metabolites of all-trans-retinol in day 10 conceptuses of vitamin A-deficient rats. Archives of Biochemistry and Biophysics. 330: 355-62. PMID 8660665 DOI: 10.1006/Abbi.1996.0262  0.377
1996 Darwish HM, DeLuca HF. Recent advances in the molecular biology of vitamin D action. Progress in Nucleic Acid Research and Molecular Biology. 53: 321-44. PMID 8650307 DOI: 10.1016/S0079-6603(08)60149-X  0.585
1996 Staal A, Van Wijnen AJ, Desai RK, Pols HA, Birkenhäger JC, Deluca HF, Denhardt DT, Stein JL, Van Leeuwen JP, Stein GS, Lian JB. Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements. Endocrinology. 137: 2001-11. PMID 8612541 DOI: 10.1210/Endo.137.5.8612541  0.409
1996 McCary LC, DeLuca HF. Osteopetrotic (op/op) mice are unable to maintain serum calcium levels despite hyperabsorption of calcium. Endocrinology. 137: 1049-56. PMID 8603573 DOI: 10.1210/Endo.137.3.8603573  0.544
1996 Mohamed MI, Beckman MJ, Meehan J, DeLuca HF. Effect of 1,25-dihydroxyvitamin D3 on mouse thymus: role of extracellular calcium. Biochimica Et Biophysica Acta. 1289: 275-83. PMID 8600985 DOI: 10.1016/0304-4165(95)00167-0  0.595
1996 Ettinger RA, DeLuca HF. The vitamin D endocrine system and its therapeutic potential Advances in Drug Research. 28: 269-312. DOI: 10.1016/S0065-2490(96)80007-4  0.615
1995 Wellik DM, DeLuca HF. Retinol in addition to retinoic acid is required for successful gestation in vitamin A-deficient rats. Biology of Reproduction. 53: 1392-7. PMID 8562696 DOI: 10.1095/Biolreprod53.6.1392  0.358
1995 Barger-Lux MJ, Heaney RP, Lanspa SJ, Healy JC, DeLuca HF. An investigation of sources of variation in calcium absorption efficiency. The Journal of Clinical Endocrinology and Metabolism. 80: 406-11. PMID 7852497 DOI: 10.1210/jcem.80.2.7852497  0.32
1995 Zierold C, Darwish HM, DeLuca HF. Two vitamin D response elements function in the rat 1,25-dihydroxyvitamin D 24-hydroxylase promoter. The Journal of Biological Chemistry. 270: 1675-8. PMID 7829502 DOI: 10.1074/Jbc.270.4.1675  0.488
1995 Elaroussi MA, DeLuca HF. Calcium uptake by chorioallantoic membrane: effects of vitamins D and K. The American Journal of Physiology. 267: E837-41. PMID 7810624 DOI: 10.1152/Ajpendo.1994.267.6.E837  0.534
1995 Munder M, Herzberg IM, Zierold C, Moss VE, Hanson K, Clagett-Dame M, Deluca HF. Identification of the porcine intestinal accessory factor that enables DNA sequence recognition by vitamin D receptor Proceedings of the National Academy of Sciences of the United States of America. 92: 2795-2799. PMID 7708726 DOI: 10.1073/Pnas.92.7.2795  0.742
1995 Biehl RR, Baker DH, DeLuca HF. 1 alpha-Hydroxylated cholecalciferol compounds act additively with microbial phytase to improve phosphorus, zinc and manganese utilization in chicks fed soy-based diets. The Journal of Nutrition. 125: 2407-16. PMID 7666260 DOI: 10.1093/Jn/125.9.2407  0.501
1995 Arbour NC, Darwish HM, DeLuca HF. Transcriptional control of the osteocalcin gene by 1,25-dihydroxyvitamin D-2 and its 24-epimer in rat osteosarcoma cells. Biochimica Et Biophysica Acta. 1263: 147-53. PMID 7640305 DOI: 10.1016/0167-4781(95)00091-T  0.61
1995 Chen KS, DeLuca HF. Cloning of the human 1 alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements. Biochimica Et Biophysica Acta. 1263: 1-9. PMID 7632726 DOI: 10.1016/0167-4781(95)00060-T  0.506
1995 Iida K, Shinki T, Yamaguchi A, DeLuca HF, Kurokawa K, Suda T. A possible role of vitamin D receptors in regulating vitamin D activation in the kidney. Proceedings of the National Academy of Sciences of the United States of America. 92: 6112-6. PMID 7597089 DOI: 10.1073/Pnas.92.13.6112  0.582
1995 Barger-Lux MJ, Heaney RP, Hayes J, DeLuca HF, Johnson ML, Gong G. Vitamin D receptor gene polymorphism, bone mass, body size, and vitamin D receptor density. Calcified Tissue International. 57: 161-2. PMID 7584878 DOI: 10.1007/Bf00298438  0.398
1995 Slatopolsky E, Finch J, Ritter C, Denda M, Morrissey J, Brown A, DeLuca H. A new analog of calcitriol, 19-nor-1,25-(OH)2D2, suppresses parathyroid hormone secretion in uremic rats in the absence of hypercalcemia. American Journal of Kidney Diseases. 26: 852-860. PMID 7485144 DOI: 10.1016/0272-6386(95)90455-7  0.541
1995 Yamamoto K, Ohta M, DeLuca HF, Yamada S. On the side chain conformation of 1α,25-dihydroxyvitamin D3 responsible for binding to the receptor Bioorganic & Medicinal Chemistry Letters. 5: 979-984. DOI: 10.1016/0960-894X(95)00142-G  0.447
1995 Sicinski RR, DeLuca HF. Synthesis of 6,7-diaza-19-norvitamin D compounds Bioorganic & Medicinal Chemistry Letters. 5: 899-904. DOI: 10.1016/0960-894X(95)00137-I  0.422
1995 Sicinski RR, DeLuca HF. Ruthenium tetroxide oxidation of Grundmann's ketone derived from vitamin D3 Bioorganic & Medicinal Chemistry Letters. 5: 159-162. DOI: 10.1016/0960-894X(94)00477-W  0.356
1994 Zierold C, Darwish HM, DeLuca HF. Identification of a vitamin D-response element in the rat calcidiol (25-hydroxyvitamin D3) 24-hydroxylase gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 900-2. PMID 8302863 DOI: 10.1073/Pnas.91.3.900  0.608
1994 Elaroussi MA, DeLuca HF. A new member to the astacin family of metalloendopeptidases: a novel 1,25-dihydroxyvitamin D-3-stimulated mRNA from chorioallantoic membrane of quail. Biochimica Et Biophysica Acta. 1217: 1-8. PMID 8286408 DOI: 10.1016/0167-4781(94)90116-3  0.403
1994 Elaroussi MA, Uhland-Smith A, Hellwig W, DeLuca HF. The role of vitamin D in chorioallantoic membrane calcium transport. Biochimica Et Biophysica Acta. 1192: 1-6. PMID 8204637 DOI: 10.1016/0005-2736(94)90135-X  0.587
1994 Koyama H, Nishizawa Y, Inaba M, Hino M, Prahl JM, DeLuca HF, Morii H. Impaired homologous upregulation of vitamin D receptor in rats with chronic renal failure. The American Journal of Physiology. 266: F706-12. PMID 8203553 DOI: 10.1152/ajprenal.1994.266.5.F706  0.331
1994 Kuno H, Kurian SM, Hendy GN, White J, deLuca HF, Evans CO, Nanes MS. Inhibition of 1,25-dihydroxyvitamin D3 stimulated osteocalcin gene transcription by tumor necrosis factor-alpha: structural determinants within the vitamin D response element. Endocrinology. 134: 2524-31. PMID 8194478 DOI: 10.1210/endo.134.6.8194478  0.421
1994 Li Z, Prahl JM, Hellwig W, DeLuca HF. Immunoaffinity purification of active rat recombinant 1,25-dihydroxyvitamin D3 receptor. Archives of Biochemistry and Biophysics. 310: 347-51. PMID 8179318 DOI: 10.1006/abbi.1994.1177  0.508
1994 Nanes MS, Kuno H, Demay MB, Kurian M, Hendy GN, DeLuca HF, Titus L, Rubin J. A single up-stream element confers responsiveness to 1,25-dihydroxyvitamin D3 and tumor necrosis factor-alpha in the rat osteocalcin gene. Endocrinology. 134: 1113-20. PMID 8119149 DOI: 10.1210/endo.134.3.8119149  0.354
1994 Okamoto Y, DeLuca HF. Separation of two forms of chick 1,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 24-hydroxylase. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 205: 52-5. PMID 8115349 DOI: 10.3181/00379727-205-43676  0.405
1994 Chen KS, DeLuca HF. Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3. Biochimica Et Biophysica Acta. 1219: 26-32. PMID 8086474 DOI: 10.1016/0167-4781(94)90242-9  0.41
1994 Jääskeläinen T, Pirskanen A, Ryhänen S, Palvimo JJ, Deluca HF, Mäenpää PH. Functional interference between AP-1 and the vitamin D receptor on osteocalcin gene expression in human osteosarcoma cells. European Journal of Biochemistry. 224: 11-20. PMID 8076631 DOI: 10.1111/J.1432-1033.1994.Tb19989.X  0.413
1994 Gallagher JC, Bishop CW, Knutson JC, Mazess RB, DeLuca HF. Effects of increasing doses of 1 alpha-hydroxyvitamin D2 on calcium homeostasis in postmenopausal osteopenic women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 9: 607-14. PMID 8053388 DOI: 10.1002/Jbmr.5650090504  0.326
1994 Liang CT, Barnes J, Imanaka S, DeLuca HF. Alterations in mRNA expression of duodenal 1,25-dihydroxyvitamin D3 receptor and vitamin D-dependent calcium binding protein in aged Wistar rats. Experimental Gerontology. 29: 179-86. PMID 8026569 DOI: 10.1016/0531-5565(94)90049-3  0.49
1994 Elaroussi MA, Prahl JM, DeLuca HF. The avian vitamin D receptors: primary structures and their origins. Proceedings of the National Academy of Sciences of the United States of America. 91: 11596-600. PMID 7972109 DOI: 10.1073/Pnas.91.24.11596  0.326
1994 Sicinski RR, Perlman KL, DeLuca HF. Synthesis and biological activity of 2-hydroxy and 2-alkoxy analogs of 1 alpha,25-dihydroxy-19-norvitamin D3. Journal of Medicinal Chemistry. 37: 3730-8. PMID 7966133 DOI: 10.1021/Jm00048A009  0.489
1994 Ross TK, Darwish HM, DeLuca HF. Molecular biology of vitamin D action Vitamins and Hormones. 49: 281-326. PMID 7810072 DOI: 10.1016/S0083-6729(08)61149-8  0.576
1994 Perlman KL, Darwish HM, DeLuca HF. 20-Oxopregnacalciferols: Vitamin D compounds that bind the progesterone receptor Tetrahedron Letters. 35: 2295-2298. DOI: 10.1016/0040-4039(94)85202-2  0.49
1994 Sicinski R, Deluca H. Synthesis, Conformational Analysis, and Biological-Activity of the 1-α,25-Dihydroxy-10,19-Dihydrovitamin D3 Isomers Bioorganic Chemistry. 22: 150-171. DOI: 10.1006/bioo.1994.1013  0.34
1993 Chen KS, Prahl JM, DeLuca HF. Isolation and expression of human 1,25-dihydroxyvitamin D3 24-hydroxylase cDNA. Proceedings of the National Academy of Sciences of the United States of America. 90: 4543-7. PMID 8506296 DOI: 10.1073/Pnas.90.10.4543  0.376
1993 Yang S, Smith C, Prahl JM, Luo X, DeLuca HF. Vitamin D deficiency suppresses cell-mediated immunity in vivo. Archives of Biochemistry and Biophysics. 303: 98-106. PMID 8489269 DOI: 10.1006/abbi.1993.1260  0.489
1993 Ross TK, Darwish HM, Moss VE, Deluca HF. Vitamin D-influenced gene expression via a ligand-independent, receptor-DNA complex intermediate Proceedings of the National Academy of Sciences of the United States of America. 90: 9257-9260. PMID 8415688 DOI: 10.1073/Pnas.90.20.9257  0.589
1993 Elaroussi MA, Deluca HF, Forte LR, Biellier HV. Survival of vitamin D-deficient embryos: time and choice of cholecalciferol or its metabolites for treatment in ovo. Poultry Science. 72: 1118-26. PMID 8391690 DOI: 10.3382/Ps.0721118  0.561
1993 Wiese RJ, Goto H, Prahl JM, Marx SJ, Thomas M, Al-Aqeel A, DeLuca HF. Vitamin D-dependency rickets type II: truncated vitamin D receptor in three kindreds Molecular and Cellular Endocrinology. 90: 197-201. PMID 8388340 DOI: 10.1016/0303-7207(93)90152-A  0.518
1993 Uhland-Smith A, DeLuca HF. The necessity for calcium for increased renal vitamin D receptor in response to 1,25-dihydroxyvitamin D. Biochimica Et Biophysica Acta. 1176: 321-6. PMID 8385999 DOI: 10.1016/0167-4889(93)90061-S  0.619
1993 Darwish HM, Burmester JK, Moss VE, DeLuca HF. Phosphorylation is involved in transcriptional activation by the 1,25-dihydroxyvitamin D3 receptor. Biochimica Et Biophysica Acta. 1167: 29-36. PMID 8384884 DOI: 10.1016/0005-2760(93)90213-S  0.532
1993 Arbour NC, Prahl JM, DeLuca HF. Stabilization of the vitamin D receptor in rat osteosarcoma cells through the action of 1,25-dihydroxyvitamin D3. Molecular Endocrinology (Baltimore, Md.). 7: 1307-12. PMID 8264662 DOI: 10.1210/Mend.7.10.8264662  0.522
1993 Reisz-Porszasz S, Reyes H, DeLuca HF, Prahl JM, Hankinson O. Investigation on the potential role of the Ah receptor nuclear translocator protein in vitamin D receptor action. Journal of Receptor Research. 13: 1147-59. PMID 8254580 DOI: 10.3109/10799899309063269  0.437
1993 Yang S, Smith C, DeLuca HF. 1α,25-dihydroxyvitamin D3 a nd 19-nor-1α,25-dihydroxyvitamin 32 suppress immunoglobulin production and thymic lymphocyte proliferation in vivo Biochimica Et Biophysica Acta. 1158: 279-286. PMID 8251528 DOI: 10.1016/0304-4165(93)90026-5  0.501
1993 Uhland-Smith A, DeLuca HF. 1,25-dihydroxycholecalciferol analogs cannot replace vitamin D in normocalcemic male rats. The Journal of Nutrition. 123: 1777-85. PMID 8229291 DOI: 10.1093/Jn/123.11.1777  0.603
1993 Hustmyer FG, DeLuca HF, Peacock M. ApaI, BsmI, EcoRV and TaqI polymorphisms at the human vitamin D receptor gene locus in Caucasians, blacks and Asians. Human Molecular Genetics. 2: 487. PMID 8099305 DOI: 10.1093/Hmg/2.4.487  0.489
1993 Uhland-Smith A, DeLuca HF. Short-term regulation of the renal vitamin D receptor in rats by 1,25-dihydroxycholecalciferol is calcium insensitive. The Journal of Nutrition. 122: 2316-21. PMID 1333519 DOI: 10.1093/Jn/122.12.2316  0.544
1993 Yamamoto K, Takahashi J, Hamano K, Yamada S, Yamaguchi K, DeLuca HF. Stereoselective syntheses of (22R)- and (22S)-22-methyl-1.alpha.,25-dihydroxyvitamin D3: active vitamin D3 analogs with restricted side-chain conformation The Journal of Organic Chemistry. 58: 2530-2537. DOI: 10.1021/Jo00061A029  0.545
1992 Inaba M, Morii H, DeLuca HF. Significance of proteolytic activity in 1,25-(OH)2D3-induced differentiation of HL-60 cells. Contributions to Nephrology. 91: 102-8. PMID 1666029 DOI: 10.1159/000420164  0.522
1992 Szpirer J, Szpirer C, Riviere M, Levan G, Marynen P, Cassiman JJ, Wiese R, DeLuca HF. The Sp1 transcription factor gene (SP1) and the 1,25-dihydroxyvitamin D3 receptor gene (VDR) are colocalized on human chromosome arm 12q and rat chromosome 7. Genomics. 11: 168-73. PMID 1662663 DOI: 10.1016/0888-7543(91)90114-T  0.321
1992 Sandgren ME, Brönnegärd M, DeLuca HF. Tissue distribution of the 1,25-dihydroxyvitamin D3 receptor in the male rat. Biochemical and Biophysical Research Communications. 181: 611-6. PMID 1661584 DOI: 10.1016/0006-291X(91)91234-4  0.528
1992 Uhland AM, Kwiecinski GG, DeLuca HF. Normalization of serum calcium restores fertility in vitamin D-deficient male rats. The Journal of Nutrition. 122: 1338-44. PMID 1588451 DOI: 10.1093/Jn/122.6.1338  0.594
1992 Kawaguchi N, DeLuca HF, Noda M. Id gene expression and its suppression by 1,25-dihydroxyvitamin D3 in rat osteoblastic osteosarcoma cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 4569-72. PMID 1584793 DOI: 10.1073/pnas.89.10.4569  0.509
1992 Hodnett DW, Jorgensen NA, Deluca HF. 1 alpha-hydroxyvitamin D3 plus 25-hydroxyvitamin D3 reduces parturient paresis in dairy cows fed high dietary calcium. Journal of Dairy Science. 75: 485-91. PMID 1560144 DOI: 10.3168/Jds.S0022-0302(92)77785-6  0.554
1992 DeLuca HF. Remembrance: discovery of the vitamin D endocrine system. Endocrinology. 130: 1763. PMID 1547708 DOI: 10.1210/Endo.130.4.1547708  0.616
1992 Hodnett DW, DeLuca HF, Jorgensen NA. Bone mineral loss during lactation occurs in absence of parathyroid tissue. The American Journal of Physiology. 262: E230-3. PMID 1539650 DOI: 10.1152/Ajpendo.1992.262.2.E230  0.33
1992 Strom M, Krisinger J, Darwish H, DeLuca HF. 1,25-Dihydroxyvitamin D and not calcium is the major regulator of calbindin-D 9-kDa mRNA levels in vivo. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 199: 369-71. PMID 1539040 DOI: 10.3181/00379727-199-43371  0.564
1992 Hodnett DW, DeLuca HF, Jorgensen NA. Intestine, bone, and mammary gland contributions to maternal plasma calcium increase after abrupt weaning. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 199: 332-6. PMID 1539036 DOI: 10.3181/00379727-199-43365  0.318
1992 DeLuca HF, Darwish HM, Ross TK, Moss VE. Mechanism of action of 1,25-dihydroxyvitamin D on target gene expression Journal of Nutritional Science and Vitaminology. 19-26. PMID 1338439 DOI: 10.3177/Jnsv.38.Special_19  0.417
1992 DeLUCA HF. New concepts of vitamin D functions. Annals of the New York Academy of Sciences. 669: 59-68. PMID 1332566 DOI: 10.1111/J.1749-6632.1992.Tb17089.X  0.588
1992 Koyama H, Prahl JM, Uhland A, Nanjo M, Inaba M, Nishizawa Y, Morii H, Nishii Y, DeLuca HF. A new, highly sensitive assay for 1,25-dihydroxyvitamin D not requiring high-performance liquid chromatography: application of monoclonal antibody against vitamin D receptor to radioreceptor assay. Analytical Biochemistry. 205: 213-9. PMID 1332539 DOI: 10.1016/0003-2697(92)90426-8  0.514
1992 Ross TK, Prahl JM, Herzberg IM, Deluca HF. Baculovirus-mediated expression of retinoic acid receptor type y in cultured insect cells reveals a difference in specific DNA-binding behavior with the 1,25-dihydroxyvitamin D3 receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 10282-10286. PMID 1332041 DOI: 10.1073/Pnas.89.21.10282  0.387
1992 Demay MB, Kiernan MS, DeLuca HF, Kronenberg HM. Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3. Proceedings of the National Academy of Sciences of the United States of America. 89: 8097-101. PMID 1325645 DOI: 10.1073/Pnas.89.17.8097  0.52
1992 Goto H, Chen KS, Prahl JM, DeLuca HF. A single receptor identical with that from intestine/T47D cells mediates the action of 1,25-dihydroxyvitamin D-3 in HL-60 cells. Biochimica Et Biophysica Acta. 1132: 103-8. PMID 1324736 DOI: 10.1016/0167-4781(92)90063-6  0.439
1992 Bortell R, Owen TA, Bidwell JP, Gavazzo P, Breen E, Van Wijnen AJ, Deluca HF, Stein JL, Lian JB, Stein GS. Vitamin D-responsive protein-DNA interactions at multiple promoter regulatory elements that contribute to the level of rat osteocalcin gene expression Proceedings of the National Academy of Sciences of the United States of America. 89: 6119-6123. PMID 1321435 DOI: 10.1073/Pnas.89.13.6119  0.412
1992 Ebeling PR, Sandgren ME, DiMagno EP, Lane AW, DeLuca HF, Riggs BL. Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women. The Journal of Clinical Endocrinology and Metabolism. 75: 176-82. PMID 1320048 DOI: 10.1210/jcem.75.1.1320048  0.501
1992 Demay MB, Kiernan MS, DeLuca HF, Kronenberg HM. Characterization of 1,25-dihydroxyvitamin D3 receptor interactions with target sequences in the rat osteocalcin gene. Molecular Endocrinology (Baltimore, Md.). 6: 557-62. PMID 1316548 DOI: 10.1210/mend.6.4.1316548  0.34
1992 Darwish HM, DeLuca HF. Identification of a 1,25-dihydroxyvitamin D3-response element in the 5'-flanking region of the rat calbindin D-9k gene. Proceedings of the National Academy of Sciences of the United States of America. 89: 603-7. PMID 1309950 DOI: 10.1073/Pnas.89.2.603  0.513
1992 Ross TK, Moss VE, Prahl JM, DeLuca HF. A nuclear protein essential for binding; of rat 1,25-dihydroxyvitamin D3 receptor to its response elements Proceedings of the National Academy of Sciences of the United States of America. 89: 256-260. PMID 1309609 DOI: 10.1073/Pnas.89.1.256  0.538
1992 Perlman KL, DeLuca HF. 1α-Hydroxy-19-nor-vitamin D C-22 aldehyde. A valuable intermediate in the synthesis of side chain modifed 1α,25-dihydroxy-19-nor-vitamin D3 Tetrahedron Letters. 33: 2937-2940. DOI: 10.1016/S0040-4039(00)79565-7  0.552
1992 Koyama H, Prahl J, Nanjo M, Inaba M, Nishizawa Y, Morii H, Nishii Y, DeLuca H. A new radioreceptor assay for serum 1,25-dihydroxyvitamin D using monoclonal antibody against vitamin D receptor Bone and Mineral. 17: 105. DOI: 10.1016/0169-6009(92)91759-C  0.475
1991 Burgos-Trinidad M, Brown AJ, DeLuca HF. A rapid assay for 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D 24-hydroxylase. Analytical Biochemistry. 190: 102-7. PMID 2178322 DOI: 10.1016/0003-2697(90)90141-U  0.528
1991 Burgos-Trinidad M, DeLuca HF. Kinetic properties of 25-hydroxyvitamin D- and 1,25-dihydroxyvitamin D-24-hydroxylase from chick kidney. Biochimica Et Biophysica Acta. 1078: 226-30. PMID 2065089 DOI: 10.1016/0167-4838(91)90562-E  0.535
1991 Jones DY, Miller KW, Koonsvitsky BP, Ebert ML, Lin PYT, Jones MB, DeLuca HF, Lawson KD. Serum 25-hydroxyvitamin D concentrations of free-living subjects consuming olestra American Journal of Clinical Nutrition. 53: 1281-1287. PMID 2021135 DOI: 10.1093/Ajcn/53.5.1281  0.516
1991 Strom M, Krisinger J, DeLuca HF. Isolation of a mRNA that encodes a putative intestinal alkaline phosphatase regulated by 1,25-dihydroxyvitamin D-3. Biochimica Et Biophysica Acta. 1090: 299-304. PMID 1954251 DOI: 10.1016/0167-4781(91)90193-P  0.42
1991 Brown TA, DeLuca HF. Photoaffinity labeling of the 1,25-dihydroxyvitamin D-3 receptor Bba - General Subjects. 1073: 324-328. PMID 1849006 DOI: 10.1016/0304-4165(91)90138-7  0.532
1991 Inaba M, Burgos-Trinidad M, DeLuca HF. Characteristics of the 25-hydroxyvitamin D3- and 1,25-dihydroxyvitamin D3-24-hydroxylase(s) from HL-60 cells. Archives of Biochemistry and Biophysics. 284: 257-63. PMID 1846519 DOI: 10.1016/0003-9861(91)90293-R  0.558
1991 Nishizawa Y, Morii H, Ogura Y, DeLuca HF. Clinical trial of 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 in uremic patients on hemodialysis: preliminary report. Contributions to Nephrology. 90: 196-203. PMID 1659967 DOI: 10.1159/000420143  0.422
1991 Brown TA, DeLuca HF. Sites of phosphorylation and photoaffinity labeling of the 1,25-dihydroxyvitamin D3 receptor Archives of Biochemistry and Biophysics. 286: 466-472. PMID 1654791 DOI: 10.1016/0003-9861(91)90067-S  0.383
1991 Ross TK, Prahl JM, Deluca HF. Overproduction of rat 1,25-dihydroxyvitamin D3 receptor in insect cells using the baculovirus expression system Proceedings of the National Academy of Sciences of the United States of America. 88: 6555-6559. PMID 1650474 DOI: 10.1073/Pnas.88.15.6555  0.497
1991 Perlman KL, Swenson RE, Paaren HE, Schnoes HK, DeLuca HF. Novel synthesis of 19-nor-vitamin D compounds Tetrahedron Letters. 32: 7663-7666. DOI: 10.1016/0040-4039(91)80559-O  0.541
1991 DeLuca HF. Recent advances in the molecular mechanism of action of 1, 25-dihydroxyvitamin D3 Journal of Bone and Mineral Metabolism. 9: 17-25. DOI: 10.1007/Bf02377980  0.581
1990 Sandgren ME, Deluca HF. An immunoradiometric assay for 1,25-dihydroxyvitamin D3 receptor. Analytical Biochemistry. 183: 57-63. PMID 2482679 DOI: 10.1016/0003-2697(89)90171-1  0.332
1990 Strom M, Sandgren ME, Brown TA, DeLuca HF. 1,25-Dihydroxyvitamin D3 up-regulates the 1,25-dihydroxyvitamin D3 receptor in vivo. Proceedings of the National Academy of Sciences of the United States of America. 86: 9770-3. PMID 2481316 DOI: 10.1073/Pnas.86.24.9770  0.513
1990 Perlman K, Kutner A, Prahl J, Smith C, Inaba M, Schnoes HK, DeLuca HF. 24-homologated 1,25-dihydroxyvitamin D3 compounds: separation of calcium and cell differentiation activities. Biochemistry. 29: 190-6. PMID 2322540 DOI: 10.1021/bi00453a026  0.403
1990 Paulson SK, Perlman K, DeLuca HF, Stern PH. 24- and 26-homo-1,25-dihydroxyvitamin D3 analogs: potencies on in vitro bone resorption differ from those reported for cell differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 5: 201-6. PMID 2316407 DOI: 10.1002/Jbmr.5650050214  0.563
1990 Barsony J, Pike JW, DeLuca HF, Marx SJ. Immunocytology with microwave-fixed fibroblasts shows 1α,25-dihydroxyvitamin d3-dependent rapid and estrogen-dependent slow reorganization of vitamin D receptors Journal of Cell Biology. 111: 2385-2395. PMID 2177476 DOI: 10.1083/jcb.111.6.2385  0.402
1990 Noda M, Vogel RL, Craig AM, Prahl J, DeLuca HF, Denhardt DT. Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression. Proceedings of the National Academy of Sciences of the United States of America. 87: 9995-9. PMID 2175918 DOI: 10.1073/Pnas.87.24.9995  0.555
1990 Sandgren ME, DeLuca HF. Serum calcium and vitamin D regulate 1,25-dihydroxyvitamin D3 receptor concentration in rat kidney in vivo. Proceedings of the National Academy of Sciences of the United States of America. 87: 4312-4. PMID 2161536 DOI: 10.1073/Pnas.87.11.4312  0.587
1990 DeLuca HF. Osteoporosis and the metabolites of vitamin D. Metabolism: Clinical and Experimental. 39: 3-9. PMID 2157943 DOI: 10.1016/0026-0495(90)90263-C  0.635
1990 Demay MB, Gerardi JM, DeLuca HF, Kronenberg HM. DNA sequences in the rat osteocalcin gene that bind the 1,25-dihydroxyvitamin D3 receptor and confer responsiveness to 1,25-dihydroxyvitamin D3. Proceedings of the National Academy of Sciences of the United States of America. 87: 369-73. PMID 2153298 DOI: 10.1073/Pnas.87.1.369  0.506
1990 Perlman KL, Sicinski RR, Schnoes HK, DeLuca HF. 1α,25-dihydroxy-19-nor-vitamin D3, a novel vitamin D-related compound with potential therapeutic activity Tetrahedron Letters. 31: 1823-1824. DOI: 10.1016/S0040-4039(00)98795-1  0.563
1990 DeLuca HF. Mechanism of action of 1,25-dihydroxyvitamin D3: 1990 version Journal of Bone and Mineral Metabolism. 8: 1-9. DOI: 10.1007/Bf02374738  0.503
1989 Satomura K, Seino Y, Yamaoka K, Tanaka Y, Ishida M, Yabuuchi H, Tanaka Y, DeLuca HF. Renal 25-hydroxyvitamin D3-1-hydroxylase in patients with renal disease. Kidney International. 34: 712-6. PMID 3199682 DOI: 10.1038/Ki.1988.237  0.324
1989 Jones G, DeLuca HF. High-performance liquid chromatography of vitamin D and its application to endocrinology. Monographs On Endocrinology. 30: 95-139. PMID 3068529 DOI: 10.1007/978-3-642-83467-7_4  0.421
1989 Link RP, DeLuca HF. On the specificity of vitamin D compounds binding to chick pig intestinal 1,25-dihydroxyvitamin D3 receptor. Steroids. 51: 583-98. PMID 2853890 DOI: 10.1016/0039-128X(88)90054-2  0.614
1989 Burmester JK, Wiese RJ, Maeda N, DeLuca HF. Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 9499-502. PMID 2849110 DOI: 10.1073/Pnas.85.24.9499  0.371
1989 DeLuca HF. Newly discovered actions of 1.25-dihydroxyvitamin D3 and osteoporosis: basis and treatment. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 191: 211-3. PMID 2740354 DOI: 10.3181/00379727-191-42910  0.504
1989 Kwiecinski GG, Petrie GI, DeLuca HF. Vitamin D is necessary for reproductive functions of the male rat. The Journal of Nutrition. 119: 741-4. PMID 2723823 DOI: 10.1093/Jn/119.5.741  0.543
1989 Kwiecinksi GG, Petrie GI, DeLuca HF. 1,25-Dihydroxyvitamin D3 restores fertility of vitamin D-deficient female rats. The American Journal of Physiology. 256: E483-7. PMID 2705521 DOI: 10.1152/Ajpendo.1989.256.4.E483  0.597
1989 Inaba M, DeLuca HF. Stabilization of 1,25-dihydroxyvitamin D-3 receptor in the human leukemia cell line, HL-60, with diisopropylfluorophosphate. Biochimica Et Biophysica Acta. 1010: 20-7. PMID 2535782 DOI: 10.1016/0167-4889(89)90179-1  0.495
1989 Darwish HM, Krisinger J, DeLuca HF. Methylation of the vitamin D-dependent CaBP gene (calbindin 9 Kd) does not mediate tissue or vitamin D regulation. Biochemical and Biophysical Research Communications. 160: 1281-9. PMID 2471520 DOI: 10.1016/S0006-291X(89)80142-1  0.5
1989 Inaba M, Okuno S, Inoue A, Nishizawa Y, Morii H, DeLuca HF. DNA binding property of vitamin D3 receptors associated with 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3. Archives of Biochemistry and Biophysics. 268: 35-9. PMID 2463789 DOI: 10.1016/0003-9861(89)90562-6  0.516
1989 Perlman KL, Schnoes HK, DeLuca HF. A convenient synthesis of (24S)-1α-hydroxyvitamin D2 Journal of the Chemical Society, Chemical Communications. 1113-1115. DOI: 10.1039/C39890001113  0.515
1988 Silva DP, Valliere CR, DeLuca HF. Lack of biological activity of physiological metabolites of all-trans-retinoic acid on vaginal epithelial differentiation. Archives of Biochemistry and Biophysics. 259: 391-401. PMID 3426235 DOI: 10.1016/0003-9861(87)90505-4  0.396
1988 Finlay JA, DeLuca HF. Purification and properties of an 18-kilodalton, 1,25-dihydroxyvitamin D3 modulated protein from embryonic chick intestine. Biochemistry. 27: 3381-7. PMID 3390438 DOI: 10.1021/Bi00409A039  0.427
1988 Ostrem VK, DeLuca HF. The vitamin D-induced differentiation of HL-60 cells: structural requirements. Steroids. 49: 73-102. PMID 3331848 DOI: 10.1016/0039-128X(87)90080-8  0.541
1988 DeLuca HF, Nakada M, Tanaka Y, Sicinski R, Phelps M. The plasma binding protein for vitamin D is a site of discrimination against vitamin D-2 compounds by the chick. Biochimica Et Biophysica Acta. 965: 16-21. PMID 3258165 DOI: 10.1016/0304-4165(88)90145-6  0.6
1988 Kobayashi Y, Nakajima M, Nakazawa M, Taguchi T, Ikekawa N, Sai H, Tanaka Y, DeLuca HF. Studies on organic fluorine compounds. LII. Synthesis and biological activity of 26,26,26,27,27-pentafluoro-1α-hydroxy-27-methoxyvitamin D3 Chemical and Pharmaceutical Bulletin. 36: 4144-4147. PMID 3245988 DOI: 10.1248/Cpb.36.4144  0.58
1988 Krisinger J, Darwish H, Maeda N, DeLuca HF. Structure and nucleotide sequence of the rat intestinal vitamin D-dependent calcium binding protein gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 8988-92. PMID 3194402 DOI: 10.1073/Pnas.85.23.8988  0.529
1988 Brown TA, Prahl JM, DeLuca HF. Partial amino acid sequence of porcine 1,25-dihydroxyvitamin D3 receptor isolated by immunoaffinity chromatography. Proceedings of the National Academy of Sciences of the United States of America. 85: 2454-8. PMID 2833740 DOI: 10.1073/Pnas.85.8.2454  0.411
1988 Ameenuddin S, Sunde ML, DeLuca HF. Lack of response of bone mineralization of chicks fed egg yolks from hens on dietary 1,25 dihydroxycholecalciferol. Poultry Science. 66: 1829-34. PMID 2833736 DOI: 10.3382/Ps.0661829  0.61
1988 Pierce EA, DeLuca HF. Regulation of the intestinal 1,25-dihydroxyvitamin D3 receptor during neonatal development in the rat. Archives of Biochemistry and Biophysics. 261: 241-9. PMID 2833163 DOI: 10.1016/0003-9861(88)90338-4  0.421
1988 DeLuca HF, Sicinski RR, Tanaka Y, Stern PH, Smith CM. Biological activity of 1,25-dihydroxyvitamin D2 and 24-epi-1,25-dihydroxyvitamin D2. The American Journal of Physiology. 254: E402-6. PMID 2833108 DOI: 10.1152/Ajpendo.1988.254.4.E402  0.603
1988 Burmester JK, Maeda N, DeLuca HF. Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 1005-9. PMID 2829212 DOI: 10.1073/Pnas.85.4.1005  0.364
1988 Deluca HF. The vitamin D story: a collaborative effort of basic science and clinical medicine 1 The Faseb Journal. 2: 224-236. DOI: 10.1096/Fasebj.2.3.3280376  0.629
1988 KUTNER A, PERLMAN KL, SICINSKI RR, PHELPS ME, SCHNOES HK, DELUCA HF. ChemInform Abstract: Vitamin D C-22 Aldehydes. New Key Intermediates for the Synthesis of Side Chain Modified Vitamin D Analogues. Cheminform. 19. DOI: 10.1002/chin.198822322  0.509
1987 Narbaitz R, Sar M, Stumpf WE, Huang S, DeLuca HF. 1,25-Dihydroxyvitamin D3 target cells in rat mammary gland. Hormone Research. 15: 263-9. PMID 6100940 DOI: 10.1159/000179465  0.565
1987 Stumpf WE, Sar M, Chen K, Morin J, DeLuca HF. Sertoli cells in the testis and epithelium of the ductuli efferentes are targets for 3H 1,25 (OH)2 vitamin D3. An autoradiographic study. Cell and Tissue Research. 247: 453-5. PMID 3815485 DOI: 10.1007/Bf00218327  0.549
1987 Paulson SK, Phelps M, DeLuca HF. Assay and properties of rat yolk sac 25-hydroxyvitamin D3 1 alpha-hydroxylase. Biochemistry. 25: 6821-6. PMID 3801395 DOI: 10.1021/Bi00370A014  0.4
1987 Kessler MA, Lamm L, Jarnagin K, DeLuca HF. 1,25-Dihydroxyvitamin D3-stimulated mRNAs in rat small intestine. Archives of Biochemistry and Biophysics. 251: 403-12. PMID 3800375 DOI: 10.1016/0003-9861(86)90346-2  0.591
1987 Brown AJ, Perlman K, Schnoes HK, DeLuca HF. A new tritium-release assay for 25-hydroxyvitamin D-1 alpha-hydroxylase. Analytical Biochemistry. 164: 424-9. PMID 3674390 DOI: 10.1016/0003-2697(87)90514-8  0.523
1987 Link RP, Kutner A, Schnoes HK, DeLuca HF. Photoaffinity labeling of serum vitamin D binding protein by 3-deoxy-3-azido-25-hydroxyvitamin D3. Biochemistry. 26: 3957-64. PMID 3651426 DOI: 10.1021/bi00387a032  0.468
1987 Barton BA, Jorgensen NA, DeLuca HF. Impact of prepartum dietary phosphorus intake on calcium homeostasis at parturition Journal of Dairy Science. 70: 1186-1191. PMID 3611474 DOI: 10.3168/Jds.S0022-0302(87)80130-3  0.427
1987 Paulson SK, DeLuca HF, Battaglia F. Plasma levels of vitamin D metabolites in fetal and pregnant ewes. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 185: 267-71. PMID 3601947 DOI: 10.3181/00379727-185-42543  0.528
1987 Sicinski RR, Tanaka Y, Phelps M, Schnoes HK, DeLuca HF. Synthesis of 25-hydroxy-[26,27-3H]vitamin D2, 1,25-dihydroxy-[26,27-3H]vitamin D2 and their (24R)-epimers. Analytical Biochemistry. 161: 96-102. PMID 3495200 DOI: 10.1016/0003-2697(87)90657-9  0.622
1987 Darwish HM, Krisinger J, Strom M, DeLuca HF. Molecular cloning of the cDNA and chromosomal gene for vitamin D-dependent calcium-binding protein of rat intestine. Proceedings of the National Academy of Sciences of the United States of America. 84: 6108-11. PMID 3476932 DOI: 10.1073/Pnas.84.17.6108  0.41
1987 Clark SA, Stumpf WE, Sar M, DeLuca HF. 1,25-Dihydroxyvitamin D3 target cells in immature pancreatic islets American Journal of Physiology - Endocrinology and Metabolism. 253. PMID 3300366 DOI: 10.1152/ajpendo.1987.253.1.E99  0.405
1987 Nolten WE, Chesney RW, Dabbagh S, Lemann J, Slatopolsky E, Klingensmith GJ, DeLuca HF. Moderate hypocalcemia due to normal serum 1,25-dihydroxyvitamin D levels in an asymptomatic kindred with familial hypoparathyroidism. The American Journal of Medicine. 82: 1157-66. PMID 3111255 DOI: 10.1016/0002-9343(87)90218-X  0.487
1987 DeLuca HF, Ostrem V. The relationship between the vitamin D system and cancer. Advances in Experimental Medicine and Biology. 206: 413-29. PMID 3035900 DOI: 10.1007/978-1-4613-1835-4_30  0.587
1987 Ostrem VK, Tanaka Y, Prahl J, DeLuca HF, Ikekawa N. 24- and 26-homo-1,25-dihydroxyvitamin D3: preferential activity in inducing differentiation of human leukemia cells HL-60 in vitro. Proceedings of the National Academy of Sciences of the United States of America. 84: 2610-4. PMID 3033654 DOI: 10.1073/Pnas.84.9.2610  0.622
1987 Ameenuddin S, Sunde ML, DeLuca HF, Cook ME. Excessive cholecalciferol in a layers diet: decline in some aspects of reproductive performance and increased bone mineralisation of progeny. British Poultry Science. 27: 671-7. PMID 3028581 DOI: 10.1080/00071668608416926  0.365
1987 Inaba M, Okuno S, Nishizawa Y, Yukioka K, Otani S, Matsui-Yuasa I, Morisawa S, DeLuca HF, Morii H. Biological activity of fluorinated vitamin D analogs at C-26 and C-27 on human promyelocytic leukemia cells, HL-60. Archives of Biochemistry and Biophysics. 258: 421-5. PMID 2823715 DOI: 10.1016/0003-9861(87)90363-8  0.598
1987 Kutner A, Perlman KL, Sicinski RR, Phelps ME, Schnoes HK, DeLuca HF. Vitamin D C-22 aldehydes. New key intermediates for the synthesis of side chain modified vitamin D analogues Tetrahedron Letters. 28: 6129-6132. DOI: 10.1016/S0040-4039(00)61826-9  0.598
1987 Sicinski RR, DeLuca HF, Schnoes HK, Tanaka Y, Smith CM. Δ22-Unsaturated analogs of vitamin D3 and their C(1)-hydroxylated derivatives Bioorganic Chemistry. 15: 152-166. DOI: 10.1016/0045-2068(87)90016-2  0.595
1987 SAI H, TAKATSUTO S, IKEKAWA N, TANAKA Y, DELUCA HF. ChemInform Abstract: Synthesis of Some Side-Chain Homologues of 1α,25-Dihydroxyvitamin D3 and Investigation of Their Biological Activities. Cheminform. 18. DOI: 10.1002/chin.198721295  0.335
1986 Sai H, Takatsuto S, Ikekawa N, Tanaka Y, DeLuca HF. Synthesis of some side-chain homologues of 1α,25-dihydroxyvitamin D3 and investigation of their biological activities Chemical and Pharmaceutical Bulletin. 34: 4508-4515. PMID 3829179 DOI: 10.1248/Cpb.34.4508  0.595
1986 Hart LE, Schnoes HK, DeLuca HF. Studies on the role of 1,25-dihydroxyvitamin D in chick embryonic development. Archives of Biochemistry and Biophysics. 250: 426-34. PMID 3777941 DOI: 10.1016/0003-9861(86)90745-9  0.586
1986 Link RP, Perlman KL, Pierce EA, Schnoes HK, DeLuca HF. Purification of human serum vitamin D-binding protein by 25-hydroxyvitamin D3-Sepharose chromatography. Analytical Biochemistry. 157: 262-9. PMID 3777429 DOI: 10.1016/0003-2697(86)90624-X  0.566
1986 Burgos-Trinidad M, Brown AJ, DeLuca HF. Solubilization and reconstitution of chick renal mitochondrial 25-hydroxyvitamin D3 24-hydroxylase. Biochemistry. 25: 2692-6. PMID 3718974 DOI: 10.1021/Bi00357A061  0.559
1986 Mathews CH, Brommage R, DeLuca HF. Role of vitamin D in neonatal skeletal development in rats. The American Journal of Physiology. 250: E725-30. PMID 3717332 DOI: 10.1152/Ajpendo.1986.250.6.E725  0.613
1986 Paulson SK, Deluca HF. Review article: Vitamin D metabolism during pregnancy Bone. 7: 331-336. PMID 3539155 DOI: 10.1016/8756-3282(86)90252-8  0.586
1986 Chertow BS, Sivitz WI, Baranetsky NG, Cordle MB, DeLuca HF. Islet insulin release and net calcium retention in vitro in vitamin D-deficient rats. Diabetes. 35: 771-5. PMID 3522318 DOI: 10.2337/Diab.35.7.771  0.444
1986 Kutner A, Renstrom B, Schnoes HK, DeLuca HF. Synthesis of coenzyme A ester of retinoic acid: intermediate in vitamin A metabolism. Proceedings of the National Academy of Sciences of the United States of America. 83: 6781-4. PMID 3462726 DOI: 10.1073/Pnas.83.18.6781  0.358
1986 Miller DA, DeLuca HF. Biosynthesis of retinoyl-β-glucuronide, a biologically active metabolite of all-trans-retinoic acid Archives of Biochemistry and Biophysics. 244: 179-186. PMID 3080946 DOI: 10.1016/0003-9861(86)90107-4  0.363
1986 Tanaka Y, Sicinski RR, DeLuca HF, Sai H, Ikekawa N. Unique rearrangement of ergocalciferol side chain in vitro: Production of a biologically highly active homologue of 1,25-dihydroxyvitamin D3 Biochemistry. 25: 5512-5518. PMID 3022793 DOI: 10.1021/Bi00367A025  0.61
1986 DeLuca HF. The metabolism and functions of vitamin D. Advances in Experimental Medicine and Biology. 196: 361-75. PMID 3012979 DOI: 10.1007/978-1-4684-5101-6_24  0.627
1986 Brommage R, Hart LE, DeLuca HF. The action of various vitamin D3 metabolites on calcium and phosphorus metabolism in chick embryo calvariae. Experientia. 42: 553-4. PMID 3011491 DOI: 10.1007/Bf01946699  0.621
1986 Clark SA, Stumpf WE, Bishop CW, DeLuca HF, Park DH, Joh TH. The adrenal: a new target organ of the calciotropic hormone 1,25-dihydroxyvitamin D3. Cell and Tissue Research. 243: 299-302. PMID 3004732 DOI: 10.1007/Bf00251043  0.564
1986 Brommage R, DeLuca HF. Evidence that 1,25-dihydroxyvitamin D3 is the physiologically active metabolite of vitamin D3. Endocrine Reviews. 6: 491-511. PMID 3000754 DOI: 10.1210/Edrv-6-4-491  0.647
1986 Dame MC, Pierce EA, Prahl JM, Hayes CE, DeLuca HF. Monoclonal antibodies to the porcine intestinal receptor for 1,25-dihydroxyvitamin D3: interaction with distinct receptor domains. Biochemistry. 25: 4523-34. PMID 2429689 DOI: 10.1021/Bi00364A011  0.689
1986 KOBAYASHI Y, NAKAZAWA M, KUMADAKI I, TAGUCHI T, OHSHIMA E, IKEKAWA N, TANAKA Y, DELUCA HF. ChemInform Abstract: Studies on Organic Fluorine Compounds. Part 50. Synthesis and Biological Activity of Zoc-Fluorovitamin D3. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198639352  0.421
1985 Abe E, Shiina Y, Miyaura C, Tanaka H, Hayashi T, Kanegasaki S, Saito M, Nishii Y, DeLuca HF, Suda T. Activation and fusion induced by 1 alpha,25-dihydroxyvitamin D3 and their relation in alveolar macrophages. Proceedings of the National Academy of Sciences of the United States of America. 81: 7112-6. PMID 6594685 DOI: 10.1073/Pnas.81.22.7112  0.448
1985 Lindgren JU, DeLuca HF, Mazess RB. Effects of 1,25(OH)2D3 on bone tissue in the rabbit: studies on fracture healing, disuse osteoporosis, and prednisone osteoporosis. Calcified Tissue International. 36: 591-5. PMID 6441632 DOI: 10.1007/Bf02405372  0.486
1985 Perlman K, Schnoes HK, Tanaka Y, DeLuca HF, Kobayashi Y, Taguchi T. Chemical synthesis of (24R)-24,25-dihydroxy[26,27-3H]vitamin D3 of high specific activity. Biochemistry. 23: 5041-8. PMID 6333896 DOI: 10.1021/bi00316a033  0.481
1985 Sjödén GO, Lindgren JU, DeLuca HF. The effect of 1 alpha-hydroxyvitamin D2 on calcium metabolism in glucocorticoid-treated rats. Bone. 6: 231-4. PMID 4052274 DOI: 10.1016/8756-3282(85)90005-5  0.511
1985 Miller DA, Stephens-Jarnagin A, DeLuca HF. The epithelial differentiating activity in vivo of (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl) -1-propenyl]benzoic acid and 4,4-difluororetinoic acid. The Biochemical Journal. 227: 311-6. PMID 3994687 DOI: 10.1042/Bj2270311  0.316
1985 Stephens-Jarnagin A, Miller DA, DeLuca HF. The growth-supporting activity of a retinoidal benzoic acid derivative and 4,4-difluororetinoic acid. Archives of Biochemistry and Biophysics. 237: 11-6. PMID 3970539 DOI: 10.1016/0003-9861(85)90248-6  0.305
1985 Brommage R, DeLuca HF. Regulation of bone mineral loss during lactation. The American Journal of Physiology. 248: E182-7. PMID 3970193 DOI: 10.1152/Ajpendo.1985.248.2.E182  0.457
1985 Pierce EA, Dame MC, Bouillon R, Van Baelen H, DeLuca HF. Monoclonal antibodies to human vitamin D-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 82: 8429-33. PMID 3936035 DOI: 10.1073/Pnas.82.24.8429  0.514
1985 Sjöden G, Smith C, Lindgren U, DeLuca HF. 1α-Hydroxyvitamin D2 is Less Toxic than 1α-Hydroxyvitamin D3 in the Rat Experimental Biology and Medicine. 178: 432-436. PMID 3871952 DOI: 10.3181/00379727-178-42028  0.527
1985 Kim YS, Clark SA, Stumpf WE, DeLuca HF. Nuclear uptake of 1,25-dihydroxyvitamin D3 in developing rodent teeth: An autoradiographic study Anatomical Record. 212: 301-306. PMID 3840659 DOI: 10.1002/Ar.1092120313  0.478
1985 Nakada M, Tanaka Y, DeLuca HF, Kobayashi Y, Ikekawa N. Biological activities and binding properties of 23,23-difluoro-25-hydroxyvitamin D3 and its 1 alpha-hydroxy derivative. Archives of Biochemistry and Biophysics. 241: 173-8. PMID 3839644 DOI: 10.1016/0003-9861(85)90373-X  0.627
1985 Steinherz R, Chesney RW, Eisenstein B, Metzker A, DeLuca HF, Phelps M. Elevated serum calcitriol concentrations do not fall in response to hyperphosphatemia in familial tumoral calcinosis. American Journal of Diseases of Children (1960). 139: 816-9. PMID 3839626 DOI: 10.1001/Archpedi.1985.02140100078036  0.403
1985 Kessler MA, DeLuca HF. The action of 1 alpha,25-dihydroxyvitamin D3 on rat small intestine: changes in translatable mRNA species. Archives of Biochemistry and Biophysics. 236: 17-25. PMID 3838129 DOI: 10.1016/0003-9861(85)90601-0  0.469
1985 Dame MC, Pierce EA, DeLuca HF. Identification of the porcine intestinal 1,25-dihydroxyvitamin D3 receptor on sodium dodecyl sulfate/polyacrylamide gels by renaturation and immunoblotting. Proceedings of the National Academy of Sciences of the United States of America. 82: 7825-9. PMID 2999778 DOI: 10.1073/Pnas.82.23.7825  0.389
1985 Yamada S, Ino E, Takayama H, Horiuchi N, Shinki T, Suda T, Jones G, DeLuca HF. Differences in the side-chain metabolism of vitamin D3 between chickens and rats. Proceedings of the National Academy of Sciences of the United States of America. 82: 7485-9. PMID 2999764 DOI: 10.1073/Pnas.82.22.7485  0.599
1985 Clark SA, Dame MC, Kim YS, Stumpf WE, DeLuca HF. 1,25-Dihydroxyvitamin D3 in teeth of rats and humans: Receptors and nuclear localization Anatomical Record. 212: 250-254. PMID 2998226 DOI: 10.1002/Ar.1092120306  0.61
1985 Helmer B, Schnoes HK, DeLuca HF. 1H nuclear magnetic resonance studies of the conformations of vitamin D compounds in various solvents Archives of Biochemistry and Biophysics. 241: 608-615. PMID 2994570 DOI: 10.1016/0003-9861(85)90587-9  0.535
1985 Nakada M, Simpson RU, DeLuca HF. Molybdate and the 1,25-dihydroxyvitamin D3 receptor from chick intestine. Archives of Biochemistry and Biophysics. 238: 517-21. PMID 2986552 DOI: 10.1016/0003-9861(85)90195-X  0.333
1985 Nakada M, DeLuca HF. The appearance of 1,25-dihydroxyvitamin D3 receptor during chick embryo development. Archives of Biochemistry and Biophysics. 238: 129-34. PMID 2984993 DOI: 10.1016/0003-9861(85)90148-1  0.373
1985 Hart LE, DeLuca HF. Effect of vitamin D3 metabolites on calcium and phosphorus metabolism in chick embryos. The American Journal of Physiology. 248: E281-5. PMID 2983566 DOI: 10.1152/ajpendo.1985.248.3.E281  0.543
1985 Dabbagh S, Chesney RW, Deluca HF, Lemann J. 443 The Effricacy And Safety Of 10<-Analogs Of Vitamin D In Pseudohypoparthyroidism (Php) Pediatric Research. 19. DOI: 10.1203/00006450-198504000-00473  0.569
1985 Sicinski RR, Tanaka Y, Schnoes HK, DeLuca HF. Synthesis of 1α,25-dihydroxyvitamin D2, its 24 epimer and related isomers, and their binding affinity for the 1,25-dihydroxyvitamin D3 receptor Bioorganic Chemistry. 13: 158-169. DOI: 10.1016/0045-2068(85)90018-5  0.483
1985 Paaren H, Mellon W, Schnoes H, DeLuca H. Ring A-stereoisomers of 1-hydroxyvitamin D3 and their relative binding affinities for the intestinal 1α,25-dihydroxyvitamin D3 receptor protein Bioorganic Chemistry. 13: 62-75. DOI: 10.1016/0045-2068(85)90008-2  0.492
1985 OHSHIMA E, SAI H, TAKATSUTO S, IKEKAWA N, KOBAYASHI Y, TANAKA Y, DELUCA HF. ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1α-FLUORO-25-HYDROXYVITAMIN D3 Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198511331  0.362
1985 OHSHIMA E, TAKATSUTO S, IKEKAWA N, DELUCA HF. ChemInform Abstract: SYNTHESIS OF 1α-FLUOROVITAMIN D3 Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198511330  0.455
1984 Brommage R, DeLuca HF. Self-selection of a high calcium diet by vitamin D-deficient lactating rats increases food consumption and milk production. The Journal of Nutrition. 114: 1377-85. PMID 6747721 DOI: 10.1093/Jn/114.8.1377  0.441
1984 Underwood JL, DeLuca HF. Vitamin D is not directly necessary for bone growth and mineralization. The American Journal of Physiology. 246: E493-8. PMID 6742112 DOI: 10.1152/ajpendo.1984.246.6.E493  0.518
1984 Brommage R, DeLuca HF. Placental transport of calcium and phosphorus is not regulated by vitamin D. The American Journal of Physiology. 246: F526-9. PMID 6720905 DOI: 10.1152/Ajprenal.1984.246.4.F526  0.545
1984 Simpson RU, Wichmann JK, Paaren HE, Schnoes HK, DeLuca HF. Metabolism of 25-hydroxyvitamin D3 by rat kidney cells in culture: isolation and identification of cis- and trans-19-nor-10-oxo-25-hydroxyvitamin D3. Archives of Biochemistry and Biophysics. 230: 21-9. PMID 6712232 DOI: 10.1016/0003-9861(84)90082-1  0.546
1984 Brommage R, DeLuca HF. Vitamin D-deficient rats produce reduced quantities of a nutritionally adequate milk. The American Journal of Physiology. 246: E221-6. PMID 6703051 DOI: 10.1152/ajpendo.1984.246.3.E221  0.493
1984 Brommage R, DeLuca HF. A maternal defect is responsible for growth failure in vitamin D-deficient rat pups. The American Journal of Physiology. 246: E216-20. PMID 6703050 DOI: 10.1152/ajpendo.1984.246.3.E216  0.528
1984 Stumpf WE, Sar M, Narbaitz R, Huang S, DeLuca HF. Autoradiographic localization of 1,25-dihydroxyvitamin D3 in rat placenta and yolk sac. Hormone Research. 18: 215-20. PMID 6688999 DOI: 10.1159/000179798  0.516
1984 Barton BA, Hodnett DW, Jorgensen NA, DeLuca HF. 24,25-Dihydroxyvitamin D3 administration increases incidence of parturient paresis Journal of Dairy Science. 67: 1236-1239. PMID 6611359 DOI: 10.3168/Jds.S0022-0302(84)81429-0  0.521
1984 Underwood JL, Phelps ME, DeLuca HF. Complex carbohydrate diets are not capable of maintaining normal plasma calcium and phosphorus levels in vitamin D-deficient rats. Proceedings of the National Academy of Sciences of the United States of America. 81: 2352-3. PMID 6585801 DOI: 10.1073/Pnas.81.8.2352  0.571
1984 Brommage R, Jarnagin K, DeLuca HF. 1,25-Dihydroxyvitamin D3 normalizes maternal food consumption and pup growth in rats. The American Journal of Physiology. 246: E227-31. PMID 6546643 DOI: 10.1152/Ajpendo.1984.246.3.E227  0.579
1984 Parfitt AM, Mathews CH, Brommage R, Jarnagin K, DeLuca HF. Calcitriol but no other metabolite of vitamin D is essential for normal bone growth and development in the rat. The Journal of Clinical Investigation. 73: 576-86. PMID 6546577 DOI: 10.1172/Jci111246  0.519
1984 Chesney RW, Kaplan BS, Phelps M, DeLuca HF. Renal tubular acidosis does not alter circulating values of calcitriol. The Journal of Pediatrics. 104: 51-5. PMID 6546310 DOI: 10.1016/S0022-3476(84)80588-0  0.532
1984 Tanaka Y, DeLuca HF. Rat renal 25-hydroxyvitamin D3 1- and 24-hydroxylases: their in vivo regulation. The American Journal of Physiology. 246: E168-73. PMID 6538071 DOI: 10.1152/ajpendo.1984.246.2.E168  0.519
1984 Sai H, Takatsuto S, Ikekawa N, Tanaka Y, Smith C, DeLuca HF. Synthesis and biological activity of (22E,24R)- and (22E,24S)-1α,24-dihydroxy-22-dehydrovitamin D3 Chemical and Pharmaceutical Bulletin. 32: 3866-3872. PMID 6529792 DOI: 10.1002/Chin.198514349  0.375
1984 Ohshima E, Sai H, Takatsuto S, Ikekawa N, Kobayashi Y, Tanaka Y, DeLuca HF. Synthesis and biological activity of 1α-fluoro-25-hydroxyvitamin D3 Chemical and Pharmaceutical Bulletin. 32: 3525-3531. PMID 6525648 DOI: 10.1002/Chin.198511331  0.486
1984 Weinstein RS, Underwood JL, Hutson MS, DeLuca HF. Bone histomorphometry in vitamin D-deficient rats infused with calcium and phosphorus The American Journal of Physiology. 246. PMID 6377910 DOI: 10.1152/ajpendo.1984.246.6.E499  0.512
1984 Sjöden G, Lindgren JU, DeLuca HF. Antirachitic activity of 1 alpha-hydroxyergocalciferol and 1 alpha-hydroxycholecalciferol in rats. The Journal of Nutrition. 114: 2043-6. PMID 6333501 DOI: 10.1093/Jn/114.11.2043  0.431
1984 Tanaka Y, DeLuca HF, Kobayashi Y, Ikekawa N. 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3: a highly potent, long-lasting analog of 1,25-dihydroxyvitamin D3. Archives of Biochemistry and Biophysics. 229: 348-54. PMID 6322691 DOI: 10.1016/0003-9861(84)90161-9  0.638
1984 Stern PH, Hamstra AJ, DeLuca HF, Bell NH. A bioassay capable of measuring 1 picogram of 1,25-dihydroxyvitamin D3. The Journal of Clinical Endocrinology and Metabolism. 46: 891-6. PMID 263737 DOI: 10.1210/Jcem-46-6-891  0.515
1984 OHSHIMA E, TAKATSUTO S, IKEKAWA N, DELUCA H. Synthesis of 1.ALPHA.-fluorovitamin D3. Chemical & Pharmaceutical Bulletin. 32: 3518-3524. DOI: 10.1248/Cpb.32.3518  0.338
1984 DeLuca HF, Schnoes HK. Method of preventing milk fever in dairy cattle Nutrition Research. 4: 1049. DOI: 10.1016/S0271-5317(84)80087-1  0.387
1984 DeLuca HF, Schnoes HK. Chapter 18. Vitamin D: Metabolism and Mechanism of Action Annual Reports in Medicinal Chemistry. 19: 179-190. DOI: 10.1016/S0065-7743(08)60694-6  0.586
1984 MORZYCKI JW, SCHNOES HK, DELUCA HF. ChemInform Abstract: SYNTHESIS OF 25-HYDROXYVITAMIN D2 AND ITS 24-EPIMER Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198447363  0.436
1984 Morzycki JW, Schnoes HK, DeLuca HF. Synthesis of 25-hydroxyvitamin D2 and its 24-epimer The Journal of Organic Chemistry. 49: 2148-2151. DOI: 10.1002/Chin.198447363  0.538
1983 Kabakoff B, Kendrick NC, DeLuca HF. 1,25-Dihydroxyvitamin C3-stimulated active uptake of phosphate by rat jejunum. The American Journal of Physiology. 243: E470-5. PMID 6897340 DOI: 10.1152/Ajpendo.1982.243.6.E470  0.509
1983 Skare KL, DeLuca HF. Biliary metabolites of all-trans-retinoic acid in the rat. Archives of Biochemistry and Biophysics. 224: 13-8. PMID 6870249 DOI: 10.1016/0003-9861(83)90185-6  0.377
1983 Stephens-Jarnagin A, Sietsema WK, Miller DA, DeLuca HF. The biological activity of rat intestinal retinoic acid metabolites in the vaginal smear assay. Archives of Biochemistry and Biophysics. 220: 502-8. PMID 6824336 DOI: 10.1016/0003-9861(83)90441-1  0.396
1983 Bushnell PJ, DeLuca HF. The effects of lactose on the absorption and retention of dietary lead. The Journal of Nutrition. 113: 365-78. PMID 6822908 DOI: 10.1093/Jn/113.2.365  0.305
1983 Lindgren U, DeLuca HF. Role of parathyroid hormone and 1,25-dihydroxyvitamin D3 in the development of osteopenia in oophorectomized rats. Calcified Tissue International. 34: 510-4. PMID 6817902 DOI: 10.1007/Bf02411294  0.563
1983 Okamoto S, Smith C, DeLuca HF, Yamada S, Takayama H. Biological activity of 24,24-difluoro-25-hydroxycholecalciferol in chicks. The Journal of Nutrition. 113: 1607-12. PMID 6688269 DOI: 10.1093/Jn/113.8.1607  0.488
1983 Narbaitz R, Stumpf WE, Sar M, Huang S, DeLuca HF. Autoradiographic localization of target cells for 1 alpha, 25-dihydroxyvitamin D3 in bones from fetal rats. Calcified Tissue International. 35: 177-82. PMID 6687827 DOI: 10.1007/Bf02405028  0.487
1983 Lindgren JU, DeLuca HF. Oral 1,25(OH)2D3: an effective prophylactic treatment for glucocorticoid osteopenia in rats. Calcified Tissue International. 35: 107-10. PMID 6687695 DOI: 10.1007/BF02405014  0.35
1983 Stern PH, Halloran BP, DeLuca HF, Hefley TJ. Responsiveness of vitamin D-deficient fetal rat limb bones to parathyroid hormone in culture. The American Journal of Physiology. 244: E421-4. PMID 6687660 DOI: 10.1152/ajpendo.1983.244.4.E421  0.518
1983 Brommage R, Jarnagin K, DeLuca HF, Yamada S, Takayama H. 1- but not 24-hydroxylation of vitamin D is required for skeletal mineralization in rats. The American Journal of Physiology. 244: E298-304. PMID 6687512 DOI: 10.1152/Ajpendo.1983.244.3.E298  0.601
1983 Jarnagin K, Brommage R, DeLuca HF, Yamada S, Takayama H. 1- but not 24-hydroxylation of vitamin D is required for growth and reproduction in rats. The American Journal of Physiology. 244: E290-7. PMID 6687511 DOI: 10.1152/Ajpendo.1983.244.3.E290  0.589
1983 Okamoto S, Tanaka Y, DeLuca HF, Kobayashi Y, Ikekawa N. Biological activity of 24,24-difluoro-1,25-dihydroxyvitamin D3. The American Journal of Physiology. 244: E159-63. PMID 6687416 DOI: 10.1152/ajpendo.1983.244.2.E159  0.532
1983 Ameenuddin S, Sunde ML, DeLuca HF, Ikekawa N, Kobayashi Y. Support of embryonic chick survival by vitamin D metabolites. Archives of Biochemistry and Biophysics. 226: 666-70. PMID 6639073 DOI: 10.1016/0003-9861(83)90336-3  0.599
1983 Miller SC, Halloran BP, DeLuca HF, Jee WS. Studies on the role of vitamin D in early skeletal development, mineralization, and growth in rats. Calcified Tissue International. 35: 455-60. PMID 6616315 DOI: 10.1007/Bf02405076  0.618
1983 Abe E, Miyaura C, Tanaka H, Shiina Y, Kuribayashi T, Suda S, Nishii Y, DeLuca HF, Suda T. 1 alpha,25-dihydroxyvitamin D3 promotes fusion of mouse alveolar macrophages both by a direct mechanism and by a spleen cell-mediated indirect mechanism. Proceedings of the National Academy of Sciences of the United States of America. 80: 5583-7. PMID 6577445 DOI: 10.1073/Pnas.80.18.5583  0.51
1983 Ikekawa N, Koizumi N, Ohshima E, Ishizuka S, Takeshita T, Tanaka Y, DeLuca HF. Natural 25,26-dihydroxyvitamin D3 is an epimeric mixture. Proceedings of the National Academy of Sciences of the United States of America. 80: 5286-8. PMID 6577424 DOI: 10.1073/Pnas.80.17.5286  0.544
1983 Shiina Y, Abe E, Miyaura C, Tanaka H, Yamada S, Ohmori M, Nakayama K, Takayama H, Matsunaga I, Nishii Y, DeLuca HF, Suda T. Biological activity of 24,24-difluoro-1 alpha, 25-dihydroxyvitamin D3 and 1 alpha, 25-dihydroxyvitamin D3-26,23-lactone in inducing differentiation of human myeloid leukemia cells. Archives of Biochemistry and Biophysics. 220: 90-4. PMID 6572492 DOI: 10.1016/0003-9861(83)90390-9  0.46
1983 Kim YS, Stumpf WE, Clark SA, Sar M, Deluca HF. Target Cells for 1,25-Dihydroxyvitamin D3 in Developing Rat Incisor Teeth Journal of Dental Research. 62: 58-59. PMID 6571855 DOI: 10.1177/00220345830620011301  0.498
1983 Chertow BS, Sivitz WI, Baranetsky NG, Clark SA, Waite A, Deluca HF. Cellular mechanisms of insulin release: the effects of vitamin D deficiency and repletion on rat insulin secretion. Endocrinology. 113: 1511-8. PMID 6352248 DOI: 10.1210/Endo-113-4-1511  0.523
1983 Tanaka Y, DeLuca HF. Stimulation of 1,25-dihydroxyvitamin D3 production by 1,25-dihydroxyvitamin D3 in the hypocalcaemic rat. The Biochemical Journal. 214: 893-7. PMID 6312966 DOI: 10.1042/bj2140893  0.534
1983 Reddy GS, Jones G, Kooh SW, Fraser D, DeLuca HF. Stimulation of 24R,25-dihydroxyvitamin D3 synthesis by metabolites of vitamin D3. The American Journal of Physiology. 245: E359-64. PMID 6312806 DOI: 10.1152/Ajpendo.1983.245.4.E359  0.494
1983 DeLuca HF, Schnoes HK. Vitamin D: recent advances. Annual Review of Biochemistry. 52: 411-39. PMID 6311080 DOI: 10.1146/Annurev.Bi.52.070183.002211  0.63
1983 Simpson RU, Hamstra A, Kendrick NC, DeLuca HF. Purification of the receptor for 1 alpha,25-dihydroxyvitamin D3 from chicken intestine. Biochemistry. 22: 2586-94. PMID 6305404 DOI: 10.1021/Bi00279A041  0.382
1983 Massaro ER, Simpson RU, DeLuca HF. Quantitation of endogenously occupied and unoccupied binding sites for 1,25-dihydroxyvitamin D3 in rat intestine. Proceedings of the National Academy of Sciences of the United States of America. 80: 2549-53. PMID 6302695 DOI: 10.1073/Pnas.80.9.2549  0.537
1983 Kabakoff B, Schnoes HK, DeLuca HF. In vitro inhibitor studies of vitamin D 25-hydroxylase in rat liver microsomes. Archives of Biochemistry and Biophysics. 221: 38-45. PMID 6299202 DOI: 10.1016/0003-9861(83)90119-4  0.536
1983 Massaro ER, Simpson RU, DeLuca HF. Glucocorticoids and appearance of 1,25-dihydroxyvitamin D3 receptor in rat intestine. The American Journal of Physiology. 244: E230-5. PMID 6299113 DOI: 10.1152/Ajpendo.1983.244.3.E230  0.514
1983 Honma Y, Hozumi M, Abe E, Konno K, Fukushima M, Hata S, Nishii Y, DeLuca HF, Suda T. 1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells. Proceedings of the National Academy of Sciences of the United States of America. 80: 201-4. PMID 6296868 DOI: 10.1073/Pnas.80.1.201  0.468
1982 Hirano Y, Ikekawa N, Tanaka Y, DeLuca HF. Synthesis of (22R)- and (22S)-22,25-Dihydroxyvitamin D3 and determination of their biological activity. Chemical & Pharmaceutical Bulletin. 29: 2254-60. PMID 7318035 DOI: 10.1248/Cpb.29.2254  0.436
1982 Pahuja DN, DeLuca HF. Stimulation of intestinal calcium transport and bone calcium mobilization by prolactin in vitamin D-deficient rats. Science (New York, N.Y.). 214: 1038-9. PMID 7302575 DOI: 10.1126/science.7302575  0.444
1982 Kendrick NC, Barr CR, Moriarity D, DeLuca HF. Effect of vitamin D deficiency on in vitro labeling of chick intestinal proteins: analysis by two-dimensional electrophoresis. Biochemistry. 20: 5288-94. PMID 7295680 DOI: 10.1021/Bi00521A030  0.534
1982 Skare KL, Sietsema WK, DeLuca HF. The biological activity of retinotaurine. The Journal of Nutrition. 112: 1626-30. PMID 7097369 DOI: 10.1093/Jn/112.8.1626  0.346
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