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Julie Pitcher - Publications

Affiliations: 
Duke University, Durham, NC 
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Robinson JD, Pitcher JA. G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade. Cellular Signalling. 25: 2831-9. PMID 24018045 DOI: 10.1016/j.cellsig.2013.08.031  0.608
2013 Johnson LR, Robinson JD, Lester KN, Pitcher JA. Distinct structural features of G protein-coupled receptor kinase 5 (GRK5) regulate its nuclear localization and DNA-binding ability. Plos One. 8: e62508. PMID 23658733 DOI: 10.1371/journal.pone.0062508  0.452
2008 Martini JS, Raake P, Vinge LE, DeGeorge BR, DeGeorge B, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ. Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 105: 12457-62. PMID 18711143 DOI: 10.1073/pnas.0803153105  0.566
2008 Martini JS, Raake P, Vinge LE, DeGeorge BR, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ. Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, (12457-12462) DOI: 10.1073/pnas.0803153105) Proceedings of the National Academy of Sciences of the United States of America. 105: 17206. DOI: 10.1073/pnas.0808974105  0.636
2007 Cotton M, Boulay PL, Houndolo T, Vitale N, Pitcher JA, Claing A. Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration. Molecular Biology of the Cell. 18: 501-11. PMID 17122362 DOI: 10.1091/Mbc.E06-06-0567  0.677
2007 Martini JS, Raake P, Vinge LE, DeGeorge BR, Chuprun JK, Harris DM, Eckhart AE, Pitcher JA, Koch WJ. A Novel Nuclear Function for GRK5 and Its Potential Role in the Hypertrophic Response Journal of Cardiac Failure. 13: S71. DOI: 10.1016/j.cardfail.2007.06.311  0.355
2006 Scott MG, Pierotti V, Storez H, Lindberg E, Thuret A, Muntaner O, Labbé-Jullié C, Pitcher JA, Marullo S. Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Molecular and Cellular Biology. 26: 3432-45. PMID 16611986 DOI: 10.1128/MCB.26.9.3432-3445.2006  0.551
2005 Cant SH, Pitcher JA. G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton. Molecular Biology of the Cell. 16: 3088-99. PMID 15843435 DOI: 10.1091/mbc.e04-10-0877  0.669
2004 Johnson LR, Scott MG, Pitcher JA. G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Molecular and Cellular Biology. 24: 10169-79. PMID 15542828 DOI: 10.1128/MCB.24.23.10169-10179.2004  0.505
2004 Fairfax BP, Pitcher JA, Scott MG, Calver AR, Pangalos MN, Moss SJ, Couve A. Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability. The Journal of Biological Chemistry. 279: 12565-73. PMID 14707142 DOI: 10.1074/jbc.M311389200  0.402
2003 Lodowski DT, Barnhill JF, Pitcher JA, Capel WD, Lefkowitz RJ, Tesmer JJ. Purification, crystallization and preliminary X-ray diffraction studies of a complex between G protein-coupled receptor kinase 2 and Gbeta1gamma2. Acta Crystallographica. Section D, Biological Crystallography. 59: 936-9. PMID 12777817 DOI: 10.1107/S0907444903002622  0.652
2003 Lodowski DT, Pitcher JA, Capel WD, Lefkowitz RJ, Tesmer JJ. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science (New York, N.Y.). 300: 1256-62. PMID 12764189 DOI: 10.1126/Science.1082348  0.697
2002 Freeman JL, Gonzalo P, Pitcher JA, Claing A, Lavergne JP, Reboud JP, Lefkowitz RJ. Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2. Biochemistry. 41: 12850-7. PMID 12379128 DOI: 10.1021/Bi020145D  0.808
2001 Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ. Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. The Journal of Biological Chemistry. 276: 15192-9. PMID 11278469 DOI: 10.1074/jbc.M009130200  0.846
2000 Freeman JL, Pitcher JA, Li X, Bennett V, Lefkowitz RJ. alpha-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro. Febs Letters. 473: 280-4. PMID 10818226 DOI: 10.1016/S0014-5793(00)01543-X  0.613
1999 Pitcher JA, Tesmer JJ, Freeman JL, Capel WD, Stone WC, Lefkowitz RJ. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. The Journal of Biological Chemistry. 274: 34531-4. PMID 10574913 DOI: 10.1074/Jbc.274.49.34531  0.75
1999 Tang Y, Hu LA, Miller WE, Ringstad N, Hall RA, Pitcher JA, DeCamilli P, Lefkowitz RJ. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12559-64. PMID 10535961 DOI: 10.1073/Pnas.96.22.12559  0.824
1999 Hall RA, Spurney RF, Premont RT, Rahman N, Blitzer JT, Pitcher JA, Lefkowitz RJ. G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction. The Journal of Biological Chemistry. 274: 24328-34. PMID 10446210 DOI: 10.1074/Jbc.274.34.24328  0.781
1999 McDonald PH, Cote NL, Lin FT, Premont RT, Pitcher JA, Lefkowitz RJ. Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation. The Journal of Biological Chemistry. 274: 10677-80. PMID 10196135 DOI: 10.1074/Jbc.274.16.10677  0.819
1998 Premont RT, Claing A, Vitale N, Freeman JL, Pitcher JA, Patton WA, Moss J, Vaughan M, Lefkowitz RJ. beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 14082-7. PMID 9826657 DOI: 10.1073/Pnas.95.24.14082  0.865
1998 Pitcher JA, Freedman NJ, Lefkowitz RJ. G protein-coupled receptor kinases. Annual Review of Biochemistry. 67: 653-92. PMID 9759500 DOI: 10.1146/annurev.biochem.67.1.653  0.842
1998 Freeman JL, De La Cruz EM, Pollard TD, Lefkowitz RJ, Pitcher JA. Regulation of G protein-coupled receptor kinase 5 (GRK5) by actin. The Journal of Biological Chemistry. 273: 20653-7. PMID 9685424 DOI: 10.1074/Jbc.273.32.20653  0.671
1998 Pitcher JA, Hall RA, Daaka Y, Zhang J, Ferguson SS, Hester S, Miller S, Caron MG, Lefkowitz RJ, Barak LS. The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin. The Journal of Biological Chemistry. 273: 12316-24. PMID 9575184 DOI: 10.1074/Jbc.273.20.12316  0.851
1998 Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, Lefkowitz RJ. The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature. 392: 626-30. PMID 9560162 DOI: 10.1038/33458  0.792
1998 Lefkowitz RJ, Pitcher J, Krueger K, Daaka Y. Mechanisms of beta-adrenergic receptor desensitization and resensitization. Advances in Pharmacology (San Diego, Calif.). 42: 416-20. PMID 9327928 DOI: 10.1016/S1054-3589(08)60777-2  0.854
1997 Lin FT, Krueger KM, Kendall HE, Daaka Y, Fredericks ZL, Pitcher JA, Lefkowitz RJ. Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1. The Journal of Biological Chemistry. 272: 31051-7. PMID 9388255 DOI: 10.1074/Jbc.272.49.31051  0.827
1997 Stoffel RH, Pitcher JA, Lefkowitz RJ. Targeting G protein-coupled receptor kinases to their receptor substrates. The Journal of Membrane Biology. 157: 1-8. PMID 9141353 DOI: 10.1007/S002329900210  0.643
1997 Daaka Y, Pitcher JA, Richardson M, Stoffel RH, Robishaw JD, Lefkowitz RJ. Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases. Proceedings of the National Academy of Sciences of the United States of America. 94: 2180-5. PMID 9122168 DOI: 10.1073/Pnas.94.6.2180  0.808
1997 Krueger KM, Daaka Y, Pitcher JA, Lefkowitz RJ. The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification. The Journal of Biological Chemistry. 272: 5-8. PMID 8995214 DOI: 10.1074/Jbc.272.1.5  0.811
1997 Lefkowitz RJ, Pitcher J, Krueger K, Daaka Y. Mechanisms of β-Adrenergic Receptor Desensitization and Resensitization Advances in Pharmacology. 42: 416-420. DOI: 10.1016/S1054-3589(08)60777-2  0.753
1996 Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, Lefkowitz RJ. Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. The Journal of Biological Chemistry. 271: 24907-13. PMID 8798768 DOI: 10.1074/Jbc.271.40.24907  0.841
1996 Fredericks ZL, Pitcher JA, Lefkowitz RJ. Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor. The Journal of Biological Chemistry. 271: 13796-803. PMID 8662852 DOI: 10.1074/Jbc.271.23.13796  0.694
1996 Premont RT, Macrae AD, Stoffel RH, Chung N, Pitcher JA, Ambrose C, Inglese J, MacDonald ME, Lefkowitz RJ. Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants. The Journal of Biological Chemistry. 271: 6403-10. PMID 8626439 DOI: 10.1074/Jbc.271.11.6403  0.731
1995 Pitcher JA, Touhara K, Payne ES, Lefkowitz RJ. Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid. The Journal of Biological Chemistry. 270: 11707-10. PMID 7744811 DOI: 10.1074/JBC.270.20.11707  0.746
1995 Pitcher JA, Payne ES, Csortos C, DePaoli-Roach AA, Lefkowitz RJ. The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. Proceedings of the National Academy of Sciences of the United States of America. 92: 8343-7. PMID 7667292 DOI: 10.1073/Pnas.92.18.8343  0.63
1993 Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG. G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins. Cold Spring Harbor Symposia On Quantitative Biology. 57: 127-33. PMID 1339651 DOI: 10.1101/Sqb.1992.057.01.016  0.845
1992 Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Tyrosine phosphorylation of G protein α subunits by pp60c-src Proceedings of the National Academy of Sciences of the United States of America. 89: 5720-5724. PMID 1378615 DOI: 10.1073/Pnas.89.13.5720  0.788
1992 Lohse MJ, Andexinger S, Pitcher J, Trukawinski S, Codina J, Faure JP, Caron MG, Lefkowitz RJ. Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems. The Journal of Biological Chemistry. 267: 8558-64. PMID 1349018  0.718
1992 Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms. Biochemistry. 31: 3193-7. PMID 1348186 DOI: 10.1021/Bi00127A021  0.781
1992 Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (New York, N.Y.). 257: 1264-7. PMID 1325672 DOI: 10.1126/Science.1325672  0.772
1988 Poulter L, Ang SG, Gibson BW, Williams DH, Holmes CF, Caudwell FB, Pitcher J, Cohen P. Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry. European Journal of Biochemistry. 175: 497-510. PMID 2842154 DOI: 10.1111/J.1432-1033.1988.Tb14222.X  0.312
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