Zvi Grossman - Publications

Affiliations: 
1979-1981 NIH, NCI 

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Grossman Z, Singh NJ, Simonetti FR, Lederman MM, Douek DC, Deeks SG. 'Rinse and Replace': Boosting T Cell Turnover To Reduce HIV-1 Reservoirs. Trends in Immunology. PMID 32414695 DOI: 10.1016/J.It.2020.04.003  0.505
2019 Grossman Z. Immunological Paradigms, Mechanisms, and Models: Conceptual Understanding Is a Prerequisite to Effective Modeling. Frontiers in Immunology. 10: 2522. PMID 31749803 DOI: 10.3389/Fimmu.2019.02522  0.453
2015 Grossman Z, Paul WE. Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function. Annual Review of Immunology. 33: 677-713. PMID 25665077 DOI: 10.1146/Annurev-Immunol-032712-100027  0.485
2014 Paul WE, Grossman Z. Pathogen-sensing and regulatory T cells: integrated regulators of immune responses. Cancer Immunology Research. 2: 503-9. PMID 24894087 DOI: 10.1158/2326-6066.Cir-14-0046  0.481
2013 Paul WE, Milner JD, Grossman Z. Pathogen-sensing, regulatory T cells, and responsiveness-tuning collectively regulate foreign- and self-antigen mediated T-cell responses. Cold Spring Harbor Symposia On Quantitative Biology. 78: 265-76. PMID 24100584 DOI: 10.1101/Sqb.2013.78.020198  0.473
2013 Petrovas C, Yamamoto T, Price DA, Rao SS, Klatt NR, Brenchley JM, Douek DC, Gostick E, Angermann BR, Grossman Z, Macallan DC, Meier-Schellersheim M, Koup RA. High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance. Journal of Virology. 87: 9836-44. PMID 23824823 DOI: 10.1128/Jvi.01001-13  0.41
2011 Younes SA, Punkosdy G, Caucheteux S, Chen T, Grossman Z, Paul WE. Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells. Plos Biology. 9: e1001171. PMID 22022231 DOI: 10.1371/Journal.Pbio.1001171  0.476
2011 Bocharov G, Quiel J, Luzyanina T, Alon H, Chiglintsev E, Chereshnev V, Meier-Schellersheim M, Paul WE, Grossman Z. Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number. Proceedings of the National Academy of Sciences of the United States of America. 108: 3318-23. PMID 21292990 DOI: 10.1073/Pnas.1019706108  0.504
2011 Quiel J, Caucheteux S, Laurence A, Singh NJ, Bocharov G, Ben-Sasson SZ, Grossman Z, Paul WE. Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number. Proceedings of the National Academy of Sciences of the United States of America. 108: 3312-7. PMID 21292989 DOI: 10.1073/Pnas.1018525108  0.407
2008 Grossman Z, Picker LJ. Pathogenic mechanisms in simian immunodeficiency virus infection. Current Opinion in Hiv and Aids. 3: 380-6. PMID 19372994 DOI: 10.1097/Coh.0B013E3282Fbaae6  0.406
2007 Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M, Lifson JD, Maino VC, Sodora DL, ... ... Grossman Z, et al. Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. The Journal of Experimental Medicine. 204: 2171-85. PMID 17724130 DOI: 10.1084/Jem.20070567  0.479
2007 Younes SA, Trautmann L, Yassine-Diab B, Kalfayan LH, Kernaleguen AE, Cameron TO, Boulassel R, Stern LJ, Routy JP, Grossman Z, Dumont AR, Sekaly RP. The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 788-97. PMID 17202340 DOI: 10.4049/Jimmunol.178.2.788  0.47
2007 Grossman Z. Looking at HIV-infected lymph nodes Blood. 109: 4116-4117. DOI: 10.1182/Blood-2007-03-075770  0.332
2007 Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M, Lifson JD, Maino VC, Sodora DL, ... ... Grossman Z, et al. Erratum: Progressive CD4+ central-memory T cell decline results in CD4+ effector-memory insufficiency and overt disease in chronic SIV infection (Journal of Experimental Medicine (September 3, 2007) 204, 9, (2171-2185)) Journal of Experimental Medicine. 204. DOI: 10.1084/Jem.20070567082907C  0.388
2006 Grossman Z, Meier-Schellersheim M, Paul WE, Picker LJ. Pathogenesis of HIV infection: what the virus spares is as important as what it destroys. Nature Medicine. 12: 289-95. PMID 16520776 DOI: 10.1038/Nm1380  0.524
2006 Grossman Z. Immune activation, viral replication and mucosal depletion Retrovirology. 3: 1-1. DOI: 10.1186/1742-4690-3-S1-S72  0.428
2005 Grossman Z. HIV Replication, Immune Activation, and CD4 Depletion: What the Virus Spares is as Significant as What It Destroys Retrovirology. 2: 1-1. DOI: 10.1186/1742-4690-2-S1-S148  0.505
2004 Dion ML, Poulin JF, Bordi R, Sylvestre M, Corsini R, Kettaf N, Dalloul A, Boulassel MR, Debré P, Routy JP, Grossman Z, Sékaly RP, Cheynier R. HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation. Immunity. 21: 757-68. PMID 15589165 DOI: 10.1016/J.Immuni.2004.10.013  0.496
2004 Grossman Z, Min B, Meier-Schellersheim M, Paul WE. Concomitant regulation of T-cell activation and homeostasis. Nature Reviews. Immunology. 4: 387-95. PMID 15122204 DOI: 10.1038/Nri1355  0.429
2004 Karlsson AC, Younger SR, Martin JN, Grossman Z, Sinclair E, Hunt PW, Hagos E, Nixon DF, Deeks SG. Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia. Aids (London, England). 18: 981-9. PMID 15096800 DOI: 10.1097/00002030-200404300-00005  0.468
2003 Younes SA, Yassine-Diab B, Dumont AR, Boulassel MR, Grossman Z, Routy JP, Sekaly RP. HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity. The Journal of Experimental Medicine. 198: 1909-22. PMID 14676302 DOI: 10.1084/Jem.20031598  0.495
2003 Grossman Z. Is SIV infection associated with CD4+ T-cell depletion? Blood. 101: 1209-1209. DOI: 10.1182/Blood-2002-12-3801  0.432
2002 Bhandoola A, Tai X, Eckhaus M, Auchincloss H, Mason K, Rubin SA, Carbone KM, Grossman Z, Rosenberg AS, Singer A. Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4+ T cells: Evidence from a lymphopenic T cell model Immunity. 17: 425-436. PMID 12387737 DOI: 10.1016/S1074-7613(02)00417-X  0.437
2002 Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RMM. CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load Journal of Immunology. 169: 3400-3406. PMID 12218162 DOI: 10.4049/Jimmunol.169.6.3400  0.479
2002 Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, et al. HIV preferentially infects HIV-specific CD4+ T cells. Nature. 417: 95-8. PMID 11986671 DOI: 10.1038/417095A  0.464
2002 Grossman Z, Meier-Schellersheim M, Sousa AE, Victorino RMM, Paul WE. CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause? Nature Medicine. 8: 319-323. PMID 11927927 DOI: 10.1038/Nm0402-319  0.507
2001 Grossman Z, Paul WE. Autoreactivity, dynamic tuning and selectivity Current Opinion in Immunology. 13: 687-698. PMID 11677091 DOI: 10.1016/S0952-7915(01)00280-1  0.458
2000 Grossman Z, Paul WE. The impact of HIV on naive T-cell homeostasis Nature Medicine. 6: 976-977. PMID 10973313 DOI: 10.1038/79667  0.466
2000 Grossman Z, Paul WE. Self-tolerance: Context dependent tuning of T cell antigen recognition Seminars in Immunology. 12: 197-203. PMID 10910740 DOI: 10.1006/Smim.2000.0232  0.484
1999 Grossman Z, Polis M, Feinberg MB, Grossman Z, Levi I, Jankelevich S, Yarchoan R, Boon J, de Wolf F, Lange JM, Goudsmit J, Dimitrov DS, Paul WE. Ongoing HIV dissemination during HAART. Nature Medicine. 5: 1099-104. PMID 10502799 DOI: 10.1038/13410  0.4
1999 Grossman Z, Herberman RB, Dimitrov DS. T Cell Turnover in SIV Infection Science. 284: 555-555. DOI: 10.1126/Science.284.5414.555A  0.411
1998 Grossman Z, Feinberg M, Kuznetsov V, Dimitrov D, Paul W. HIV infection: How effective is drug combination treatment? Immunology Today. 19: 528-532. PMID 9818549 DOI: 10.1016/S0167-5699(98)01353-X  0.383
1998 Grossman Z, Feinberg MB, Paul WE. Multiple modes of cellular activation and virus transmission in HIV infection: A role for chronically and latently infected cells in sustaining viral replication Proceedings of the National Academy of Sciences of the United States of America. 95: 6314-6319. PMID 9600962 DOI: 10.1073/Pnas.95.11.6314  0.438
1998 Grossman Z, Herberman RB, Vatnik N, Intrator N. Conservation of total T-cell counts during HIV infection: Alternative hypotheses and implications Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 17: 450-457. PMID 9562048 DOI: 10.1097/00042560-199804150-00010  0.486
1997 Grossman Z, Herberman RB. T-cell homeostasis in HIV infection is neither failing nor blind: Modified cell counts reflect an adaptive response of the host Nature Medicine. 3: 486-490. PMID 9142108 DOI: 10.1038/Nm0597-486  0.485
1997 Grossman Z, Herberman RB. Mathematical models of HIV pathogenesis Nature Medicine. 3: 936-937. DOI: 10.1038/Nm0997-936B  0.31
1996 Grossman Z, Singer A. Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus Proceedings of the National Academy of Sciences of the United States of America. 93: 14747-14752. PMID 8962126 DOI: 10.1073/Pnas.93.25.14747  0.45
1993 Grossman Z, Bentwich Z, Herberman RB. From HIV infection to AIDS : are the manifestations of effective immune resistance misinterpreted ? Clinical Immunology and Immunopathology. 69: 123-135. PMID 8403549 DOI: 10.1006/Clin.1993.1160  0.518
1993 Grossman Z. Cellular tolerance as a dynamic state of the adaptable lymphocyte. Immunological Reviews. 133: 45-73. PMID 8225370 DOI: 10.1111/J.1600-065X.1993.Tb01509.X  0.447
1992 Grossman Z, Paul WE. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. Proceedings of the National Academy of Sciences of the United States of America. 89: 10365-9. PMID 1438221 DOI: 10.1073/Pnas.89.21.10365  0.422
1991 Grossman Z. Hypothesis on the existence of self-supervised immune surveillance Journal of Neuroimmunology. 35: 139. DOI: 10.1016/0165-5728(91)91101-H  0.314
1987 Grossman Z, Greenblatt CL, Cohen IR. Parasite immunology and lymphocyte population dynamics. Journal of Theoretical Biology. 121: 129-39. PMID 3795992 DOI: 10.1016/S0022-5193(86)80088-1  0.418
1986 Grossman Z, Herberman RB. 'Immune surveillance' without immunogenicity. Immunology Today. 7: 128-131. PMID 25289999 DOI: 10.1016/0167-5699(86)90075-7  0.446
1986 Moscovitch M, Grossman Z, Rosen D, Berke G. Maturation of cytolytic T lymphocytes. Cellular Immunology. 102: 52-67. PMID 3492278 DOI: 10.1016/0008-8749(86)90325-4  0.418
1986 Grossman Z. On the nature of the dynamic processes leading to blast cell dominance in chronic myelocytic leukemia Mathematical Modelling. 7: 1255-1268. DOI: 10.1016/0270-0255(86)90080-1  0.348
1984 Grossman Z. Recognition of self and regulation of specificity at the level of cell populations. Immunological Reviews. 79: 119-138. PMID 6204924 DOI: 10.1111/J.1600-065X.1984.Tb00490.X  0.397
1982 Grossman Z. Recognition of self, balance of growth and competition: horizontal networks regulate immune responsiveness European Journal of Immunology. 12: 747-756. PMID 6982821 DOI: 10.1002/Eji.1830120909  0.452
1982 Grossman Z, Herberman RB. Hypothesis On The Development Of Natural Killer Cells And Their Relationship To T Cells Nk Cells and Other Natural Effector Cells. 229-238. DOI: 10.1016/B978-0-12-341360-4.50040-8  0.449
1980 Grossman Z, Asofsky R, DeLisi C. The dynamics of antibody secreting cell production: regulation of growth and oscillations in the response to T-independent antigens. Journal of Theoretical Biology. 84: 49-92. PMID 6968005 DOI: 10.1016/S0022-5193(80)81037-X  0.565
1980 Grossman Z, Berke G. Tumor escape from immune elimination Journal of Theoretical Biology. 83: 267-296. PMID 6967536 DOI: 10.1016/0022-5193(80)90293-3  0.372
1980 Grossman Z, Cohen IR. A theoretical analysis of the phenotypic expression of immune response genes. European Journal of Immunology. 10: 633-40. PMID 6156849 DOI: 10.1002/Eji.1830100811  0.369
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