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Ekaterina Rogaeva - Publications

Affiliations: 
Tanz Centre for Research in Neurodegenerative Disease University of Toronto, Toronto, ON, Canada 
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238 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Rogaeva E, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311  0.56
2023 Li S, Poon CH, Zhang Z, Yue M, Chen R, Zhang Y, Hossain MF, Pan Y, Zhao J, Rong L, Chu LW, Shea YF, Rogaeva E, Tu J, St George-Hyslop P, et al. MicroRNA-128 suppresses tau phosphorylation and reduces amyloid-beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's disease. Cns Neuroscience & Therapeutics. PMID 36880288 DOI: 10.1111/cns.14143  0.465
2022 Couto B, Martinez-Valbuena I, Lee S, Alfradique-Dunham I, Perrin RJ, Perlmutter JS, Cruchaga C, Kim A, Visanji N, Sato C, Rogaeva E, Lang AE, Kovacs GG. Protracted Course-Progressive Supranuclear Palsy (PC-PSP). European Journal of Neurology. PMID 35384155 DOI: 10.1111/ene.15346  0.307
2021 Dilliott AA, Abdelhady A, Sunderland KM, Farhan SMK, Abrahao A, Binns MA, Black SE, Borrie M, Casaubon LK, Dowlatshahi D, Finger E, Fischer CE, Frank A, Freedman M, Grimes D, ... ... Rogaeva E, et al. Contribution of rare variant associations to neurodegenerative disease presentation. Npj Genomic Medicine. 6: 80. PMID 34584092 DOI: 10.1038/s41525-021-00243-3  0.361
2021 Zhang Y, Zhang Y, Aman Y, Ng CT, Chau WH, Zhang Z, Yue M, Bohm C, Jia Y, Li S, Yuan Q, Griffin J, Chiu K, Wong DSM, Wang B, ... ... Rogaeva E, et al. Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway. Brain : a Journal of Neurology. PMID 34428276 DOI: 10.1093/brain/awab134  0.455
2021 Lai D, Alipanahi B, Fontanillas P, Schwantes-An TH, Aasly J, Alcalay RN, Beecham GW, Berg D, Bressman S, Brice A, Brockman K, Clark L, Cookson M, Das S, Van Deerlin V, ... ... Rogaeva E, et al. Genome-wide association studies of LRRK2 modifiers of Parkinson's disease. Annals of Neurology. PMID 33938021 DOI: 10.1002/ana.26094  0.323
2021 Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, ... ... Rogaeva E, et al. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature Genetics. PMID 33589841 DOI: 10.1038/s41588-021-00785-3  0.551
2021 Ayodele T, Rogaeva E, Kurup JT, Beecham G, Reitz C. Early-Onset Alzheimer's Disease: What Is Missing in Research? Current Neurology and Neuroscience Reports. 21: 4. PMID 33464407 DOI: 10.1007/s11910-020-01090-y  0.314
2020 Reitz C, Rogaeva E, Beecham GW. Late-onset vs nonmendelian early-onset Alzheimer disease: A distinction without a difference? Neurology. Genetics. 6: e512. PMID 33225065 DOI: 10.1212/NXG.0000000000000512  0.366
2020 Ramirez J, Dilliott AA, Binns MA, Breen DP, Evans EC, Beaton D, McLaughlin PM, Kwan D, Holmes MF, Ozzoude M, Scott CJM, Strother SC, Symons S, Swartz RH, Grimes D, ... ... Rogaeva E, et al. Parkinson's Disease, NOTCH3 Genetic Variants, and White Matter Hyperintensities. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32573853 DOI: 10.1002/Mds.28171  0.374
2020 Vasilevskaya A, Taghdiri F, Burke C, Tarazi A, Naeimi SA, Khodadadi M, Goswami R, Sato C, Grinberg M, Moreno D, Wennberg R, Mikulis D, Green R, Colella B, Davis KD, ... ... Rogaeva E, et al. Interaction of APOE4 alleles and PET tau imaging in former contact sport athletes. Neuroimage. Clinical. 26: 102212. PMID 32097865 DOI: 10.1016/J.Nicl.2020.102212  0.368
2020 Keith JL, Swinkin E, Gao A, Alminawi S, Zhang M, McGoldrick P, McKeever P, Robertson J, Rogaeva E, Zinman L. Neuropathologic description of mutated amyotrophic lateral sclerosis. Neurology. Genetics. 6: e394. PMID 32042922 DOI: 10.1212/Nxg.0000000000000394  0.359
2020 Orme T, Hernandez D, Ross OA, Kun-Rodrigues C, Darwent L, Shepherd CE, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, et al. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathologica Communications. 8: 5. PMID 31996268 DOI: 10.1186/S40478-020-0879-Z  0.661
2019 Mirza SS, Saeed U, Knight J, Ramirez J, Stuss DT, Keith J, Nestor SM, Yu D, Swardfager W, Rogaeva E, St George Hyslop P, Black SE, Masellis M. ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia. Neurology. PMID 31575706 DOI: 10.1212/Wnl.0000000000008377  0.351
2019 Dilliott AA, Farhan SM, Ghani M, Sato C, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, Bulman DE, Rogaeva E, Black SE, Finger E, et al. Genetic variation in the Ontario Neurodegenerative Disease Research Initiative. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 1-24. PMID 31217043 DOI: 10.1017/Cjn.2019.228  0.448
2019 Guerreiro R, Escott-Price V, Hernandez DG, Kun-Rodrigues C, Ross OA, Orme T, Neto JL, Carmona S, Dehghani N, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, ... ... Rogaeva E, et al. Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease. PMID 30953760 DOI: 10.1016/J.Nbd.2019.04.004  0.558
2019 Mutsaerts HJMM, Mirza SS, Petr J, Thomas DL, Cash DM, Bocchetta M, de Vita E, Metcalfe AWS, Shirzadi Z, Robertson AD, Tartaglia MC, Mitchell SB, Black SE, Freedman M, Tang-Wai D, ... ... Rogaeva E, et al. Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study. Brain : a Journal of Neurology. PMID 30847466 DOI: 10.1093/Brain/Awz039  0.361
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Rogaeva E, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.35
2019 Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Rogaeva E, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/S00401-019-01962-9  0.433
2019 Ruiz-Lopez M, Freitas ME, Oliveira LM, Munhoz RP, Fox SH, Rohani M, Rogaeva E, Lang AE, Fasano A. Diagnostic delay in Parkinson's disease caused by PRKN mutations. Parkinsonism & Related Disorders. PMID 30692050 DOI: 10.1016/J.Parkreldis.2019.01.010  0.386
2018 Kun-Rodrigues C, Orme T, Carmona S, Hernandez DG, Ross OA, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, ... ... Rogaeva E, et al. A comprehensive screening of copy number variability in dementia with Lewy bodies. Neurobiology of Aging. PMID 30448004 DOI: 10.1016/J.Neurobiolaging.2018.10.019  0.592
2018 Picillo M, Lizarraga KJ, Friesen EL, Chau H, Zhang M, Sato C, Rooke G, Munhoz RP, Rogaeva E, Fraser PE, Kalia SK, Kalia LV. Parkinsonism due to A53E α-synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30423204 DOI: 10.1002/Mds.27506  0.366
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Rogaeva E, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.501
2018 Saeed U, Mirza SS, MacIntosh BJ, Herrmann N, Keith J, Ramirez J, Nestor SM, Yu Q, Knight J, Swardfager W, Potkin SG, Rogaeva E, George-Hyslop PS, Black SE, Masellis M. APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29782824 DOI: 10.1016/J.Jalz.2018.04.005  0.404
2018 Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, ... ... Rogaeva E, et al. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet. Neurology. PMID 29724592 DOI: 10.1016/S1474-4422(18)30126-1  0.361
2018 Dilliott AA, Farhan SMK, Ghani M, Sato C, Liang E, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, Bulman DE, Rogaeva E, Lang A, et al. Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease. Journal of Visualized Experiments : Jove. PMID 29683450 DOI: 10.3791/57266  0.339
2018 Wang B, Bao S, Zhang Z, Zhou X, Wang J, Fan Y, Zhang Y, Li Y, Chen L, Jia Y, Li J, Li M, Zheng W, Mu N, Wang L, ... ... Rogaeva E, et al. A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population. Neurobiology of Aging. PMID 29656768 DOI: 10.1016/J.Neurobiolaging.2018.03.006  0.62
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Rogaeva E, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027  0.391
2018 van den Heuvel L, Lim AS, Visanji NP, Huang J, Ghate T, Mestre TA, AlDakheel A, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Pondal M, Faust-Socher A, Rogaeva E, et al. Actigraphy Detects Greater Intra-Individual Variability During Gait in Non-Manifesting LRRK2 Mutation Carriers. Journal of Parkinson's Disease. 8: 131-139. PMID 29480219 DOI: 10.3233/Jpd-171151  0.387
2018 Rao S, Ghani M, Guo Z, Deming Y, Wang K, Sims R, Mao C, Yao Y, Cruchaga C, Stephan DA, Rogaeva E. An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk. Neurobiology of Aging. PMID 29395286 DOI: 10.1016/J.Neurobiolaging.2017.12.027  0.38
2018 Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, ... ... Rogaeva E, et al. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. The Lancet. Neurology. 17: 64-74. PMID 29263008 DOI: 10.1016/S1474-4422(17)30400-3  0.577
2018 Hirsch-Reinshagen V, Nicholson A, Pottier C, Baker M, Hsiung G, Krieger C, Boylan K, Weintraub S, Mesulam M, Bigio E, Zinman L, Keith J, Rogaeva E, Zivkovic S, Lacomis D, et al. Clinical and neuropathological features of ALS/FTD with TIA1 mutations Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 45: S5-S5. DOI: 10.1017/CJN.2018.48  0.302
2018 Zhang M, Dilliott AA, Robinson J, Hegele R, Comishen M, Sato C, Mayeux R, George-Hyslop PS, Freedman M, Rogaeva E. P2-131: Analysis Of A Family With Identical Triplets Discordant For Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.817  0.421
2017 Hirsch-Reinshagen V, Pottier C, Nicholson AM, Baker M, Hsiung GR, Krieger C, Sengdy P, Boylan KB, Dickson DW, Mesulam M, Weintraub S, Bigio E, Zinman L, Keith J, Rogaeva E, et al. Clinical and neuropathological features of ALS/FTD with TIA1 mutations. Acta Neuropathologica Communications. 5: 96. PMID 29216908 DOI: 10.1017/Cjn.2018.48  0.386
2017 Straub IR, Janer A, Weraarpachai W, Zinman L, Robertson J, Rogaeva E, Shoubridge EA. Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS. Human Molecular Genetics. PMID 29121267 DOI: 10.1093/Hmg/Ddx393  0.34
2017 Curtis AF, Masellis M, Hsiung GR, Moineddin R, Zhang K, Au B, Millett G, Mackenzie I, Rogaeva E, Tierney MC. Sex differences in the prevalence of genetic mutations in FTD and ALS: A meta-analysis. Neurology. PMID 28916533 DOI: 10.1212/Wnl.0000000000004494  0.417
2017 Vardarajan BN, Tosto G, Lefort R, Yu L, Bennett DA, De Jager PL, Barral S, Reyes-Dumeyer D, Nagy PL, Lee JH, Cheng R, Medrano M, Lantigua R, Rogaeva E, St George-Hyslop P, et al. Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease. Neurology. Genetics. 3: e178. PMID 28852706 DOI: 10.1212/Nxg.0000000000000178  0.629
2017 Wang H, Williams D, Griffin J, Saito T, Saido TC, Fraser PE, Rogaeva E, Schmitt-Ulms G. Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease. Plos One. 12: e0182844. PMID 28832675 DOI: 10.1371/Journal.Pone.0182844  0.377
2017 Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GR, Krieger C, ... ... Rogaeva E, et al. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Neuron. 95: 808-816.e9. PMID 28817800 DOI: 10.1016/J.Neuron.2017.07.025  0.414
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Rogaeva E, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.607
2017 Blauwendraat C, Faghri F, Pihlstrom L, Geiger JT, Elbaz A, Lesage S, Corvol JC, May P, Nicolas A, Abramzon Y, Murphy NA, Gibbs JR, Ryten M, Ferrari R, Bras J, ... ... Rogaeva E, et al. NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases. Neurobiology of Aging. PMID 28602509 DOI: 10.1016/J.Neurobiolaging.2017.05.009  0.429
2017 Keith J, Gao FQ, Noor R, Kiss A, Balasubramaniam G, Au K, Rogaeva E, Masellis M, Black SE. Collagenosis of the Deep Medullary Veins: An Underrecognized Pathologic Correlate of White Matter Hyperintensities and Periventricular Infarction? Journal of Neuropathology and Experimental Neurology. 76: 299-312. PMID 28431180 DOI: 10.1093/Jnen/Nlx009  0.349
2017 Tierney MC, Curtis AF, Masellis M, Hsiung GR, Moineddin R, Zhang K, Au B, Millett G, Mackenzie IR, Rogaeva E. Sex Differences In The Prevalence Of Genetic Mutations In Ftd And Als: A Meta-Analysis Alzheimers & Dementia. 13: 1491. DOI: 10.1016/J.Jalz.2017.07.578  0.357
2016 Farhan SMK, Dilliott AA, Ghani M, Sato C, Liang E, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, St George-Hyslop P, Bulman DE, Rogaeva E, et al. The ONDRISeq panel: custom-designed next-generation sequencing of genes related to neurodegeneration. Npj Genomic Medicine. 1: 16032. PMID 29263818 DOI: 10.1038/Npjgenmed.2016.32  0.625
2016 Zhang M, Schmitt-Ulms G, Sato C, Xi Z, Zhang Y, Zhou Y, St George-Hyslop P, Rogaeva E. Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining. Plos One. 11: e0168812. PMID 28005991 DOI: 10.1371/Journal.Pone.0168812  0.476
2016 Lam B, Khan A, Keith J, Rogaeva E, Bilbao J, St George-Hyslop P, Ghani M, Freedman M, Stuss DT, Chow T, Black SE, Masellis M. Characterizing familial corticobasal syndrome due to Alzheimer's pathology and PSEN1 mutations. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27743520 DOI: 10.1016/J.Jalz.2016.08.014  0.624
2016 Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, ... ... Rogaeva E, et al. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiology of Aging. PMID 27666590 DOI: 10.1016/J.Neurobiolaging.2016.08.023  0.566
2016 Bamji-Mirza M, Li Y, Najem D, Liu QY, Walker D, Lue LF, Stupak J, Chan K, Li J, Ghani M, Yang Z, Rogaeva E, Zhang W. Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models. Journal of Alzheimer's Disease : Jad. PMID 27314524 DOI: 10.3233/Jad-150965  0.383
2016 Xiao S, MacNair L, McLean J, McGoldrick P, McKeever P, Soleimani S, Keith J, Zinman L, Rogaeva E, Robertson J. C9orf72 isoforms in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration. Brain Research. PMID 27134035 DOI: 10.1016/J.Brainres.2016.04.062  0.315
2016 Ghani M, Sato C, Kakhki EG, Gibbs JR, Traynor B, St George-Hyslop P, Rogaeva E. Mutation analysis of the MS4A and TREM gene clusters in a case-control Alzheimer's disease data set. Neurobiology of Aging. PMID 27084067 DOI: 10.1016/J.Neurobiolaging.2016.03.009  0.547
2016 Taghdiri F, Sato C, Ghani M, Moreno D, Rogaeva E, Tartaglia MC. Novel GRN Mutations in Patients with Corticobasal Syndrome. Scientific Reports. 6: 22913. PMID 26961809 DOI: 10.1038/Srep22913  0.402
2016 Itzcovich T, Xi Z, Martinetto H, Chrem-Méndez P, Russo MJ, de Ambrosi B, Uchitel OD, Nogués M, Silva E, Rojas G, Bagnatti P, Amengual A, Campos J, Rogaeva E, St George-Hyslop P, et al. Analysis of C9orf72 in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Argentina. Neurobiology of Aging. PMID 26925510 DOI: 10.1016/J.Neurobiolaging.2016.02.001  0.535
2016 Mutsaerts HJMM, Rohrer JD, Thomas DL, Cash DM, Vita Ed, Nicholas JM, Swieten JCv, Dopper EGP, Jiskoot LC, Minkelen Rv, Rombouts SARB, Dick KM, Bocchetta M, Cardoso MJ, Espak M, ... ... Rogaeva E, et al. Cerebral Perfusion As An Imaging Biomarker Of Presymptomatic Genetic Frontotemporal Dementia: Preliminary Results From The Genetic Frontotemporal Dementia Initiative (Genfi) Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.772  0.44
2016 Ghani M, Sato C, kakhki EG, Gibbs JR, Traynor B, George-Hyslop PS, Rogaeva E. Mutation Analysis Of The Ms4A And Trem Gene-Clusters In A Case-Control Alzheimer’S Disease Dataset Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1340  0.372
2015 Guerreiro R, Escott-Price V, Darwent L, Parkkinen L, Ansorge O, Hernandez DG, Nalls MA, Clark L, Honig L, Marder K, van der Flier W, Holstege H, Louwersheimer E, Lemstra A, Scheltens P, ... Rogaeva E, et al. Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiology of Aging. PMID 26643944 DOI: 10.1016/J.Neurobiolaging.2015.10.028  0.604
2015 Gijselinck I, Van Mossevelde S, van der Zee J, Sieben A, Engelborghs S, De Bleecker J, Ivanoiu A, Deryck O, Edbauer D, Zhang M, Heeman B, Bäumer V, Van den Broeck M, Mattheijssens M, Peeters K, ... Rogaeva E, et al. The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter. Molecular Psychiatry. PMID 26481318 DOI: 10.1038/Mp.2015.159  0.345
2015 Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, ... ... Rogaeva E, et al. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. Jama Neurology. PMID 26366463 DOI: 10.1001/Jamaneurol.2015.1700  0.593
2015 Wang L, Aasly JO, Annesi G, Bardien S, Bozi M, Brice A, Carr J, Chung SJ, Clarke C, Crosiers D, Deutschländer A, Eckstein G, Farrer MJ, Goldwurm S, Garraux G, ... ... Rogaeva E, et al. Large-scale assessment of polyglutamine repeat expansions in Parkinson disease. Neurology. PMID 26354989 DOI: 10.1212/Wnl.0000000000002016  0.322
2015 Tosto G, Fu H, Vardarajan BN, Lee JH, Cheng R, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Elkind MS, Wright CB, Sacco RL, Pericak-Vance M, Farrer L, Rogaeva E, et al. F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease. Annals of Clinical and Translational Neurology. 2: 810-20. PMID 26339675 DOI: 10.1002/Acn3.223  0.613
2015 Anor CJ, Xi Z, Zhang M, Moreno D, Sato C, Rogaeva E, Tartaglia MC. Mutation analysis of C9orf72 in patients with corticobasal syndrome. Neurobiology of Aging. PMID 26166205 DOI: 10.1016/J.Neurobiolaging.2015.06.008  0.383
2015 Vardarajan BN, Ghani M, Kahn A, Sheikh S, Sato C, Barral S, Lee JH, Cheng R, Reitz C, Lantigua R, Reyes-Dumeyer D, Medrano M, Jimenez-Velazquez IZ, Rogaeva E, St George-Hyslop P, et al. Rare coding mutations identified by sequencing of Alzheimer's disease GWAS loci. Annals of Neurology. PMID 26101835 DOI: 10.1002/Ana.24466  0.603
2015 Zhang M, Xi Z, Zinman L, Bruni AC, Maletta RG, Curcio SA, Rainero I, Rubino E, Pinessi L, Nacmias B, Sorbi S, Galimberti D, Lang AE, Fox S, Surace EI, ... ... Rogaeva E, et al. Mutation analysis of CHCHD10 in different neurodegenerative diseases. Brain : a Journal of Neurology. PMID 25833818 DOI: 10.1093/Brain/Awv082  0.469
2015 Rohrer JD, Nicholas JM, Cash DM, van Swieten J, Dopper E, Jiskoot L, van Minkelen R, Rombouts SA, Cardoso MJ, Clegg S, Espak M, Mead S, Thomas DL, De Vita E, Masellis M, ... ... Rogaeva E, et al. Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis. The Lancet. Neurology. 14: 253-62. PMID 25662776 DOI: 10.1016/S1474-4422(14)70324-2  0.42
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Rogaeva E, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.614
2015 Vardarajan BN, Zhang Y, Lee JH, Cheng R, Bohm C, Ghani M, Reitz C, Reyes-Dumeyer D, Shen Y, Rogaeva E, St George-Hyslop P, Mayeux R. Coding mutations in SORL1 and Alzheimer disease. Annals of Neurology. 77: 215-27. PMID 25382023 DOI: 10.1002/Ana.24305  0.633
2015 Ghani M, Lang AE, Zinman L, Nacmias B, Sorbi S, Bessi V, Tedde A, Tartaglia MC, Surace EI, Sato C, Moreno D, Xi Z, Hung R, Nalls MA, Singleton A, ... ... Rogaeva E, et al. Mutation analysis of patients with neurodegenerative disorders using NeuroX array. Neurobiology of Aging. 36: 545.e9-14. PMID 25174650 DOI: 10.1016/J.Neurobiolaging.2014.07.038  0.635
2015 Vardarajan BN, Ghani M, Kahn A, Sheikh S, Sato C, Barral S, Lee JH, Cheng R, Reitz C, Lantigua R, Reyes-Dumeyer D, Medrano M, Jimenez-Velazquez IZ, Rogaeva E, George-Hyslop PS, et al. Rare coding mutations identified by targeted sequencing of Alzheimer’s disease loci detected in genome-wide association studies Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.313  0.372
2015 Ghani M, Reitz C, Cheng R, Lee JH, Vardarajan BN, Tosto G, George-Hyslop PS, Mayeux R, Rogaeva E. Genome wide analyses of runs of homozygosity among african americans revealed further evidence of recessive inheritance for Alzheimer’s disease Alzheimers & Dementia. 11: 228. DOI: 10.1016/J.Jalz.2015.07.262  0.335
2014 Vardarajan BN, Schaid DJ, Reitz C, Lantigua R, Medrano M, Jiménez-Velázquez IZ, Lee JH, Ghani M, Rogaeva E, St George-Hyslop P, Mayeux RP. Inbreeding among Caribbean Hispanics from the Dominican Republic and its effects on risk of Alzheimer disease. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 25394174 DOI: 10.1038/Gim.2014.161  0.582
2014 Theuns J, Verstraeten A, Sleegers K, Wauters E, Gijselinck I, Smolders S, Crosiers D, Corsmit E, Elinck E, Sharma M, Krüger R, Lesage S, Brice A, Chung SJ, Kim MJ, ... ... Rogaeva E, et al. Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease. Neurology. 83: 1906-13. PMID 25326098 DOI: 10.1212/Wnl.0000000000001012  0.334
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Rogaeva E, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.596
2014 Bras J, Guerreiro R, Darwent L, Parkkinen L, Ansorge O, Escott-Price V, Hernandez DG, Nalls MA, Clark LN, Honig LS, Marder K, Van Der Flier WM, Lemstra A, Scheltens P, Rogaeva E, et al. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Human Molecular Genetics. 23: 6139-46. PMID 24973356 DOI: 10.1093/Hmg/Ddu334  0.616
2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, ... ... Rogaeva E, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1  0.595
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Rogaeva E, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661  0.451
2014 Xi Z, Rainero I, Rubino E, Pinessi L, Bruni AC, Maletta RG, Nacmias B, Sorbi S, Galimberti D, Surace EI, Zheng Y, Moreno D, Sato C, Liang Y, Zhou Y, ... ... Rogaeva E, et al. Hypermethylation of the CpG-island near the C9orf72 G₄C₂-repeat expansion in FTLD patients. Human Molecular Genetics. 23: 5630-7. PMID 24908669 DOI: 10.1093/Hmg/Ddu279  0.507
2014 Johnson JO, Pioro EP, Boehringer A, Chia R, Feit H, Renton AE, Pliner HA, Abramzon Y, Marangi G, Winborn BJ, Gibbs JR, Nalls MA, Morgan S, Shoai M, Hardy J, ... ... Rogaeva E, et al. Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. Nature Neuroscience. 17: 664-6. PMID 24686783 DOI: 10.1038/Nn.3688  0.38
2014 Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, Jeng AT, Cooper B, Skorupa T, Carrell D, Levitch D, ... ... Rogaeva E, et al. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature. 505: 550-4. PMID 24336208 DOI: 10.1038/Nature12825  0.618
2014 Hardy J, Rogaeva E. Motor neuron disease and frontotemporal dementia: sometimes related, sometimes not. Experimental Neurology. 262: 75-83. PMID 24246281 DOI: 10.1016/J.Expneurol.2013.11.006  0.38
2014 Rogaeva E, Ghani M, Reitz C, Lee JH, Vardarajan BN, Tosto G, George-Hyslop PS, Mayeux R. Search For Recessive Alzheimer Disease Loci In African Americans By Genome-Wide Study Of Runs Of Homozygosity Alzheimers & Dementia. 10: 324. DOI: 10.1016/J.Jalz.2014.05.293  0.363
2014 Ando K, Brion J, Stygelbout V, Tomimura K, Suain V, Authelet M, Dedecker R, Chanut A, Belkouch M, Lacor PN, Lavaur J, Sazdovitch V, Rogaeva E, Potier M, Duyckaerts C. Alzheimer Risk Factor Picalm Is Involved In Tau Pathology In Alzheimer And Other Tauopathies Alzheimers & Dementia. 10: 297. DOI: 10.1016/J.Jalz.2014.04.495  0.369
2014 Vardarajan BN, Zhang Y, Lee JH, Cheng R, Bohm C, Reitz C, Shen Y, Rogaeva E, George-Hyslop PS, Mayeux R. Coding Mutations In Sorl1 Implicate Alternate App Processing Mechanisms In Alzheimer'S Disease Alzheimers & Dementia. 10: 134. DOI: 10.1016/J.Jalz.2014.04.074  0.416
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Rogaeva E, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802  0.608
2013 Butcher NJ, Kiehl TR, Hazrati LN, Chow EW, Rogaeva E, Lang AE, Bassett AS. Association between early-onset Parkinson disease and 22q11.2 deletion syndrome: identification of a novel genetic form of Parkinson disease and its clinical implications. Jama Neurology. 70: 1359-66. PMID 24018986 DOI: 10.1001/Jamaneurol.2013.3646  0.303
2013 Ghani M, Sato C, Lee JH, Reitz C, Moreno D, Mayeux R, St George-Hyslop P, Rogaeva E. Evidence of recessive Alzheimer disease loci in a Caribbean Hispanic data set: genome-wide survey of runs of homozygosity. Jama Neurology. 70: 1261-7. PMID 23978990 DOI: 10.1001/Jamaneurol.2013.3545  0.623
2013 Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R, et al. Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Translational Psychiatry. 3: e256. PMID 23673467 DOI: 10.1038/Tp.2013.13  0.441
2013 Ando K, Brion JP, Stygelbout V, Suain V, Authelet M, Dedecker R, Chanut A, Lacor P, Lavaur J, Sazdovitch V, Rogaeva E, Potier MC, Duyckaerts C. Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains. Acta Neuropathologica. 125: 861-78. PMID 23589030 DOI: 10.1007/S00401-013-1111-Z  0.435
2013 Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, De Deyn PP, Van Broeckhoven C, Mann DM, Snowden J, ... ... Rogaeva E, et al. A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. Jama Neurology. 70: 727-35. PMID 23588557 DOI: 10.1001/Jamaneurol.2013.1925  0.431
2013 Galimberti D, Fenoglio C, Serpente M, Villa C, Bonsi R, Arighi A, Fumagalli GG, Del Bo R, Bruni AC, Anfossi M, Clodomiro A, Cupidi C, Nacmias B, Sorbi S, Piaceri I, ... ... Rogaeva E, et al. Autosomal dominant frontotemporal lobar degeneration due to the C9ORF72 hexanucleotide repeat expansion: late-onset psychotic clinical presentation. Biological Psychiatry. 74: 384-91. PMID 23473366 DOI: 10.1016/J.Biopsych.2013.01.031  0.409
2013 Sinha N, Grimes D, Tokuhiro S, Sato C, Rogaeva E, Woulfe J. Variant Alzheimer's disease with spastic paraparesis and supranuclear gaze palsy. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 40: 249-51. PMID 23419577 DOI: 10.1017/S0317167100013822  0.432
2013 Ghani M, Sato C, Rogaeva E. Segmental duplications in genome-wide significant loci and housekeeping genes; warning for GAPDH and ACTB. Neurobiology of Aging. 34: 1710.e1-4. PMID 23238109 DOI: 10.1016/J.Neurobiolaging.2012.11.006  0.331
2013 Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, et al. TREM2 variants in Alzheimer's disease. The New England Journal of Medicine. 368: 117-27. PMID 23150934 DOI: 10.1056/Nejmoa1211851  0.64
2013 Kakhki MG, Sato C, Lee J, Reitz C, Moreno D, Mayeux R, George-Hyslop PS, Rogaeva E. Evidence of recessive Alzheimer's disease loci in Caribbean Hispanics: Genome-wide survey of runs of homozygosity Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.283  0.4
2012 Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Bertram L, Bozi M, Barcikowska M, Crosiers D, Clarke CE, Facheris MF, Farrer M, Garraux G, Gispert S, Auburger G, ... ... Rogaeva E, et al. A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants. Journal of Medical Genetics. 49: 721-6. PMID 23125461 DOI: 10.1136/Jmedgenet-2012-101155  0.443
2012 Rubino E, Rainero I, Chiò A, Rogaeva E, Galimberti D, Fenoglio P, Grinberg Y, Isaia G, Calvo A, Gentile S, Bruni AC, St George-Hyslop PH, Scarpini E, Gallone S, Pinessi L, et al. SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Neurology. 79: 1556-62. PMID 22972638 DOI: 10.1212/Wnl.0B013E31826E25Df  0.563
2012 Xi Z, Zinman L, Grinberg Y, Moreno D, Sato C, Bilbao JM, Ghani M, Hernández I, Ruiz A, Boada M, Morón FJ, Lang AE, Marras C, Bruni A, Colao R, ... ... Rogaeva E, et al. Investigation of c9orf72 in 4 neurodegenerative disorders. Archives of Neurology. 69: 1583-90. PMID 22964832 DOI: 10.1001/Archneurol.2012.2016  0.54
2012 Barnett C, Grinberg Y, Ghani M, Rogaeva E, Katzberg H, St George-Hyslop P, Bril V. Fcγ receptor polymorphisms do not predict response to intravenous immunoglobulin in myasthenia gravis. Journal of Clinical Neuromuscular Disease. 14: 1-6. PMID 22922574 DOI: 10.1097/Cnd.0B013E31825C566B  0.521
2012 Hazrati LN, Van Cauwenberghe C, Brooks PL, Brouwers N, Ghani M, Sato C, Cruts M, Sleegers K, St George-Hyslop P, Van Broeckhoven C, Rogaeva E. Genetic association of CR1 with Alzheimer's disease: a tentative disease mechanism. Neurobiology of Aging. 33: 2949.e5-2949.e12. PMID 22819390 DOI: 10.1016/J.Neurobiolaging.2012.07.001  0.549
2012 Bernardi L, Frangipane F, Smirne N, Colao R, Puccio G, Curcio SA, Mirabelli M, Maletta R, Anfossi M, Gallo M, Geracitano S, Conidi ME, Di Lorenzo R, Clodomiro A, Cupidi C, ... ... Rogaeva E, et al. Epidemiology and genetics of frontotemporal dementia: a door-to-door survey in southern Italy. Neurobiology of Aging. 33: 2948.e1-2948.e10. PMID 22819134 DOI: 10.1016/J.Neurobiolaging.2012.06.017  0.617
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Rogaeva E, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.526
2012 Ghani M, Pinto D, Lee JH, Grinberg Y, Sato C, Moreno D, Scherer SW, Mayeux R, St George-Hyslop P, Rogaeva E. Genome-wide survey of large rare copy number variants in Alzheimer's disease among Caribbean hispanics. G3 (Bethesda, Md.). 2: 71-8. PMID 22384383 DOI: 10.1534/G3.111.000869  0.545
2012 Bettens K, Brouwers N, Engelborghs S, Lambert JC, Rogaeva E, Vandenberghe R, Le Bastard N, Pasquier F, Vermeulen S, Van Dongen J, Mattheijssens M, Peeters K, Mayeux R, St George-Hyslop P, Amouyel P, et al. Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk. Molecular Neurodegeneration. 7: 3. PMID 22248099 DOI: 10.1186/1750-1326-7-3  0.607
2012 Reitz C, Cheng R, Schupf N, Lee JH, Mehta PD, Rogaeva E, St George-Hyslop P, Mayeux R. Association between variants in IDE-KIF11-HHEX and plasma amyloid β levels. Neurobiology of Aging. 33: 199.e13-7. PMID 20724036 DOI: 10.1016/J.Neurobiolaging.2010.07.005  0.543
2011 Renton AE, Majounie E, Waite A, Simón-Sánchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, Kalimo H, Paetau A, Abramzon Y, Remes AM, Kaganovich A, ... ... Rogaeva E, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron. 72: 257-68. PMID 21944779 DOI: 10.1016/J.Neuron.2011.09.010  0.427
2011 Sharma M, Maraganore DM, Ioannidis JP, Riess O, Aasly JO, Annesi G, Abahuni N, Bentivoglio AR, Brice A, Van Broeckhoven C, Chartier-Harlin MC, Destée A, Djarmati A, Elbaz A, Farrer M, ... ... Rogaeva E, et al. Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease. Neurobiology of Aging. 32: 2108.e1-5. PMID 21782285 DOI: 10.1016/J.Neurobiolaging.2011.05.024  0.385
2011 Marras C, Schüle B, Schuele B, Munhoz RP, Rogaeva E, Langston JW, Kasten M, Meaney C, Klein C, Wadia PM, Lim SY, Chuang RS, Zadikof C, Steeves T, Prakash KM, et al. Phenotype in parkinsonian and nonparkinsonian LRRK2 G2019S mutation carriers. Neurology. 77: 325-33. PMID 21753163 DOI: 10.1212/Wnl.0B013E318227042D  0.396
2011 Reitz C, Rogaeva E, Foroud T, Farrer LA. Genetics and genomics of late-onset Alzheimer's disease and its endophenotypes. International Journal of Alzheimer's Disease. 2011: 284728. PMID 21660206 DOI: 10.4061/2011/284728  0.492
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Rogaeva E, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  0.515
2011 Reitz C, Tokuhiro S, Clark LN, Conrad C, Vonsattel JP, Hazrati LN, Palotás A, Lantigua R, Medrano M, Z Jiménez-Velázquez I, Vardarajan B, Simkin I, Haines JL, Pericak-Vance MA, Farrer LA, ... ... Rogaeva E, et al. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Annals of Neurology. 69: 47-64. PMID 21280075 DOI: 10.1002/Ana.22308  0.439
2011 Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, et al. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Archives of Neurology. 68: 99-106. PMID 21220680 DOI: 10.1001/Archneurol.2010.346  0.595
2011 Ehsani S, Huo H, Salehzadeh A, Pocanschi CL, Watts JC, Wille H, Westaway D, Rogaeva E, St George-Hyslop PH, Schmitt-Ulms G. Family reunion--the ZIP/prion gene family. Progress in Neurobiology. 93: 405-20. PMID 21163327 DOI: 10.1016/J.Pneurobio.2010.12.001  0.556
2011 Lee JH, Cheng R, Barral S, Reitz C, Medrano M, Lantigua R, Jiménez-Velazquez IZ, Rogaeva E, St George-Hyslop PH, Mayeux R. Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals. Archives of Neurology. 68: 320-8. PMID 21059989 DOI: 10.1001/Archneurol.2010.292  0.597
2011 Robertson J, Bilbao J, Zinman L, Hazrati LN, Tokuhiro S, Sato C, Moreno D, Strome R, Mackenzie IR, Rogaeva E. A novel double mutation in FUS gene causing sporadic ALS. Neurobiology of Aging. 32: 553.e27-30. PMID 20561714 DOI: 10.1016/J.Neurobiolaging.2010.05.015  0.38
2011 Rogaeva E, Ghani M, Pinto D, Lee J, Reitz C, Scherer S, Mayeux R, George-Hyslop PS. Genome-Wide Analysis of Large Rare Copy Number Variations in Alzheimer Disease Among Caribbean Hispanics Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.538  0.374
2010 Pollen DA, Baker S, Hinerfeld D, Swearer J, Evans BA, Evans JE, Caselli R, Rogaeva E, St George-Hyslop P, Moonis M. Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4. Alzheimer's Research & Therapy. 2: 31. PMID 21062519 DOI: 10.1186/Alzrt55  0.526
2010 Gabryelewicz T, Masellis M, Berdynski M, Bilbao JM, Rogaeva E, St George-Hyslop P, Barczak A, Czyzewski K, Barcikowska M, Wszolek Z, Black SE, Zekanowski C. Intra-familial clinical heterogeneity due to FTLD-U with TDP-43 proteinopathy caused by a novel deletion in progranulin gene (PGRN). Journal of Alzheimer's Disease : Jad. 22: 1123-33. PMID 20930269 DOI: 10.3233/Jad-2010-101413  0.637
2010 Silveira-Moriyama L, Munhoz RP, de J Carvalho M, Raskin S, Rogaeva E, de C Aguiar P, Bressan RA, Felicio AC, Barsottini OG, Andrade LA, Chien HF, Bonifati V, Barbosa ER, Teive HA, Lees AJ. Olfactory heterogeneity in LRRK2 related Parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 2879-83. PMID 20818658 DOI: 10.1002/Mds.23325  0.343
2010 Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, et al. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Archives of Neurology. 67: 1473-84. PMID 20697030 DOI: 10.1001/Archneurol.2010.201  0.577
2010 Butler R, Beattie BL, Thong UP, Dwosh E, Guimond C, Feldman HH, Hsiung GY, Rogaeva E, St George-Hyslop P, Sadovnick AD. A novel PS1 gene mutation in a large Aboriginal kindred. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 37: 359-64. PMID 20481270 DOI: 10.1017/S0317167100010258  0.621
2010 Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, ... ... Rogaeva E, et al. Worldwide distribution of PSEN1 Met146Leu mutation: a large variability for a founder mutation. Neurology. 74: 798-806. PMID 20164095 DOI: 10.1212/Wnl.0B013E3181D52785  0.428
2010 Kerman A, Liu HN, Croul S, Bilbao J, Rogaeva E, Zinman L, Robertson J, Chakrabartty A. Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form Acta Neuropathologica. 119: 335-344. PMID 20111867 DOI: 10.1007/S00401-010-0646-5  0.348
2010 Orlacchio A, Babalini C, Borreca A, Patrono C, Massa R, Basaran S, Munhoz RP, Rogaeva EA, St George-Hyslop PH, Bernardi G, Kawarai T. SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 133: 591-8. PMID 20110243 DOI: 10.1093/Brain/Awp325  0.554
2010 Guerreiro RJ, Baquero M, Blesa R, Boada M, Brás JM, Bullido MJ, Calado A, Crook R, Ferreira C, Frank A, Gómez-Isla T, Hernández I, Lleó A, Machado A, Martínez-Lage P, ... ... Rogaeva E, et al. Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP. Neurobiology of Aging. 31: 725-31. PMID 18667258 DOI: 10.1016/J.Neurobiolaging.2008.06.012  0.376
2010 Marras C, Klein C, Lang AE, Wakutani Y, Moreno D, Sato C, Yip E, Munhoz RP, Lohmann K, Djarmati A, Bi A, Rogaeva E. LRRK2 and Parkin mutations in a family with parkinsonism-Lack of genotype-phenotype correlation. Neurobiology of Aging. 31: 721-2. PMID 18644660 DOI: 10.1016/J.Neurobiolaging.2008.05.030  0.393
2010 Reitz C, Tokuhiro S, Clark L, Conrad C, Vonsattel J, Lantigua R, Medrano M, Simkin I, Haines J, Pericak-Vance M, Farrer L, Lee J, Rogaeva E, George-Hyslop PS, Mayeux R. Sorcs1 Alters APP Processing and Variants may Increase Alzheimer's Disease Risk Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.091  0.403
2010 Lee JH, Cheng R, Barral S, Reitz C, Medrano M, Lantigua R, Jiménez-Velazquez IZ, Rogaeva E, George-Hyslop PS, Mayeux R. Genome Wide Association Study in Late-onset Alzheimer'S Disease Among Caribbean Hispanics Supports Clu, Picalm, Bin1, And Cugbp2 And Identifies Novel Loci Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.040  0.419
2010 Reitz C, Cheng R, Rogaeva E, Lee J, Tokuhiro S, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Kamboh IM, Prince J, Maier W, Riemenschneider M, Owen M, et al. Meta-analysis of the association between SORL1 variants and Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.351  0.426
2009 Sidransky E, Nalls MA, Aasly JO, Aharon-Peretz J, Annesi G, Barbosa ER, Bar-Shira A, Berg D, Bras J, Brice A, Chen CM, Clark LN, Condroyer C, De Marco EV, Dürr A, ... ... Rogaeva E, et al. Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. The New England Journal of Medicine. 361: 1651-61. PMID 19846850 DOI: 10.1056/Nejmoa0901281  0.431
2009 Liu HN, Sanelli T, Horne P, Pioro EP, Strong MJ, Rogaeva E, Bilbao J, Zinman L, Robertson J. Lack of evidence of monomer/misfolded superoxide dismutase-1 in sporadic amyotrophic lateral sclerosis. Annals of Neurology. 66: 75-80. PMID 19670443 DOI: 10.1002/Ana.21704  0.355
2009 Daude N, Wohlgemuth S, Rogaeva E, Farid AH, Heaton M, Westaway D. Frequent missense and insertion/deletion polymorphisms in the ovine Shadoo gene parallel species-specific variation in PrP. Plos One. 4: e6538. PMID 19657386 DOI: 10.1371/Journal.Pone.0006538  0.351
2009 Evans BA, Evans JE, Baker SP, Kane K, Swearer J, Hinerfeld D, Caselli R, Rogaeva E, St George-Hyslop P, Moonis M, Pollen DA. Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 27: 519-24. PMID 19478483 DOI: 10.1159/000221835  0.523
2009 Munhoz RP, Teive HA, Francisco AN, Raskin S, Rogaeva E. Unilateral pallidotomy in a patient with parkinsonism and G2019S LRRK2 mutation. Movement Disorders. 24: 791-792. PMID 19012346 DOI: 10.1002/Mds.21818  0.327
2009 Barral S, Lee JH, Cheng R, Reitz C, Santana V, Williamson J, Lantigua R, Rogaeva E, Hyslop PSG, Mayeux R. Genetic variants in 14q chromosomal region are associated with memory in late-onset Alzheimer's disease Alzheimers & Dementia. 5: 150. DOI: 10.1016/J.Jalz.2009.05.517  0.376
2009 Butler R, Beattie BL, Dwosh E, Feldman H, Guimond C, Hsiung R, Thong UP, George-Hyslop PS, Rogaeva E, Sadovnick AD. A novel PS1 mutation in a large aboriginal kindred with early onset familial Alzheimer's disease from a remote community in northern British Columbia Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.516  0.445
2009 Lee JH, Cheng R, Rogaeva E, George-Hyslop PS, Mayeux R. Examination of TOMM40, APOE, and PCDH11X in Caribbean Hispanics with late-onset Alzheimer's disease Alzheimers & Dementia. 5: 472. DOI: 10.1016/J.Jalz.2009.04.806  0.422
2009 Reitz C, Lee J, Cheng R, Rogaeva E, Tokuhiro S, Clark L, George-Hyslop PS, Mayeux R. The sortilin-related receptor (SORL1) influences variation in memory in late-onset Alzheimer disease Alzheimers & Dementia. 5: 464. DOI: 10.1016/J.Jalz.2009.04.780  0.327
2008 Rogaeva E, Hardy J. Gaucher and Parkinson diseases: Unexpectedly related Neurology. 70: 2272-2273. PMID 18541881 DOI: 10.1212/01.Wnl.0000314657.92762.0F  0.389
2008 Pettersen JA, Sathiyamoorthy G, Gao FQ, Szilagyi G, Nadkarni NK, St George-Hyslop P, Rogaeva E, Black SE. Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Archives of Neurology. 65: 790-5. PMID 18541799 DOI: 10.1001/Archneur.65.6.790  0.561
2008 Lee JH, Cheng R, Rogaeva E, Meng Y, Stern Y, Santana V, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Farrer LA, St George-Hyslop P, Mayeux R. Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease. Neurogenetics. 9: 127-38. PMID 18340469 DOI: 10.1007/S10048-008-0122-8  0.603
2008 Munhoz RP, Wakutani Y, Marras C, Teive HA, Raskin S, Werneck LC, Moreno D, Sato C, Lang AE, Rogaeva E. The G2019S LRRK2 mutation in Brazilian patients with Parkinson's disease: phenotype in monozygotic twins. Movement Disorders. 23: 290-294. PMID 17999435 DOI: 10.1002/Mds.21832  0.392
2008 Lee JH, Barral S, Cheng R, Chacon I, Santana V, Williamson J, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawarai T, St George-Hyslop P, et al. Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease. Neurogenetics. 9: 51-60. PMID 17940814 DOI: 10.1007/S10048-007-0103-3  0.504
2008 Xiao S, Sato C, Kawarai T, Goodall EF, Pall HS, Zinman LH, Robertson J, Morrison K, Rogaeva E. Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis. Neurobiology of Aging. 29: 1279-82. PMID 17383054 DOI: 10.1016/J.Neurobiolaging.2007.02.022  0.377
2008 Wakutani Y, Pardossi-Piquard R, Gu Y, Murakami T, Yang S, Bohm C, Chen F, Yip E, Rogaeva E, Fraser P, Westaway D, Hyslop PS. P3-376: Gene expression profiling in a transgenic mouse model of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1946  0.378
2008 Frangipane F, Colao R, Mirabelli M, Puccio G, Bernardi L, Tomaino C, Anfossi M, Gallo M, Geracitano S, Maletta R, Smirne N, Elder J, Kawarai T, Sato C, Pradella S, ... ... Rogaeva E, et al. P3-279: A novel progranulin mutation in a large frontotemporal dementia calabrian kindred Alzheimer's & Dementia. 4: T604-T604. DOI: 10.1016/J.Jalz.2008.05.1847  0.394
2008 Rogaeva E, Lee JH, Meng Y, Wakutani Y, Zou F, Moreno D, Cheng R, Sorbi S, Bruni A, Duara R, Graff-Radford N, Petersen RC, Dickson D, Younkin S, Farrer LA, et al. P3-258: Further evidence of genetic association between SORL1 and Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1826  0.429
2008 Lee JH, Rogaeva E, Park N, Santana V, Williamson J, Bodnar K, Jimenez-Velazquez I, Medrano M, George-Hyslop PS, Mayeux R. P3-235: Genetic contributions to age-at-onset variation in early-onset Alzheimer's disease in Caribbean Hispanic families Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1802  0.434
2007 Hinerfeld DA, Moonis M, Swearer JM, Baker SP, Caselli RJ, Rogaeva E, St George-Hyslop P, Pollen DA. Statins differentially affect amyloid precursor protein metabolism in presymptomatic PS1 and non-PS1 subjects. Archives of Neurology. 64: 1672-3. PMID 17998454 DOI: 10.1001/Archneur.64.11.1672  0.496
2007 Bruni AC, Momeni P, Bernardi L, Tomaino C, Frangipane F, Elder J, Kawarai T, Sato C, Pradella S, Wakutani Y, Anfossi M, Gallo M, Geracitano S, Costanzo A, Smirne N, ... ... Rogaeva E, et al. Heterogeneity within a large kindred with frontotemporal dementia: a novel progranulin mutation. Neurology. 69: 140-7. PMID 17620546 DOI: 10.1212/01.wnl.0000265220.64396.b4  0.563
2007 Klein C, Lohmann-Hedrich K, Rogaeva E, Schlossmacher MG, Lang AE. Deciphering the role of heterozygous mutations in genes associated with parkinsonism. The Lancet. Neurology. 6: 652-62. PMID 17582365 DOI: 10.1016/S1474-4422(07)70174-6  0.443
2007 Lee JH, Cheng R, Schupf N, Manly J, Lantigua R, Stern Y, Rogaeva E, Wakutani Y, Farrer L, St George-Hyslop P, Mayeux R. The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Archives of Neurology. 64: 501-6. PMID 17420311 DOI: 10.1001/Archneur.64.4.501  0.586
2007 Matsui M, Kawarai T, Hase Y, Tomimoto H, Iseki K, Rogaeva E, Orlacchio A, Bernardi G, St George-Hyslop P, Takahashi R, Matsui M. A novel mutation in the SPG3A gene (atlastin) in hereditary spastic paraplegia. Journal of Neurology. 254: 972-4. PMID 17380240 DOI: 10.1007/S00415-006-0446-Y  0.554
2007 Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nature Genetics. 39: 168-77. PMID 17220890 DOI: 10.1038/Ng1943  0.602
2007 Shibata N, Kawarai T, Meng Y, Lee JH, Lee HS, Wakutani Y, Shibata E, Pathan N, Bi A, Sato C, Sorbi S, Bruni AC, Duara R, Mayeux R, Farrer LA, ... ... Rogaeva E, et al. Association studies between the plasmin genes and late-onset Alzheimer's disease. Neurobiology of Aging. 28: 1041-3. PMID 16828203 DOI: 10.1016/J.Neurobiolaging.2006.05.028  0.375
2006 Momeni P, Schymick J, Jain S, Cookson MR, Cairns NJ, Greggio E, Greenway MJ, Berger S, Pickering-Brown S, Chiò A, Fung HC, Holtzman DM, Huey ED, Wassermann EM, Adamson J, ... ... Rogaeva E, et al. Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. Bmc Neurology. 6: 44. PMID 17166276 DOI: 10.1186/1471-2377-6-44  0.592
2006 Klünemann HH, Fronhöfer W, Werner-Füchtenbusch D, Grasbon-Frodl E, Kloiber S, Wurster HW, St George-Hyslop PH, Rogaeva E. Characterization of the kindred of Alois Alzheimer's patient with plaque-only dementia. Alzheimer Disease and Associated Disorders. 20: 291-4. PMID 17132975 DOI: 10.1097/01.wad.0000213855.81989.c8  0.595
2006 Lee JH, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M, Arriaga A, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawarai T, St George-Hyslop P, Mayeux R. Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease. Archives of Neurology. 63: 1591-8. PMID 17101828 DOI: 10.1001/Archneur.63.11.1591  0.548
2006 Chishti MA, Bohlega S, Ahmed M, Loualich A, Carroll P, Sato C, St George-Hyslop P, Westaway D, Rogaeva E. T313M PINK1 mutation in an extended highly consanguineous Saudi family with early-onset Parkinson disease. Archives of Neurology. 63: 1483-5. PMID 17030667 DOI: 10.1001/Archneur.63.10.1483  0.56
2006 Masellis M, Momeni P, Meschino W, Heffner R, Elder J, Sato C, Liang Y, St George-Hyslop P, Hardy J, Bilbao J, Black S, Rogaeva E. Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome. Brain : a Journal of Neurology. 129: 3115-23. PMID 17030534 DOI: 10.1093/Brain/Awl276  0.608
2006 Momeni P, Rogaeva E, Van Deerlin V, Yuan W, Grafman J, Tierney M, Huey E, Bell J, Morris CM, Kalaria RN, van Rensburg SJ, Niehaus D, Potocnik F, Kawarai T, Salehi-Rad S, et al. Genetic variability in CHMP2B and frontotemporal dementia. Neuro-Degenerative Diseases. 3: 129-33. PMID 16954699 DOI: 10.1159/000094771  0.617
2006 Rogaeva E, Kawarai T, George-Hyslop PS. Genetic complexity of Alzheimer's disease: successes and challenges. Journal of Alzheimer's Disease. 9: 381-387. PMID 16914876 DOI: 10.3233/Jad-2006-9S343  0.484
2006 Rogaeva E, Zadikoff C, Ponesse J, Schmitt-Ulms G, Kawarai T, Sato C, Salehi-Rad S, St George-Hyslop P, Lang AE. Childhood onset in familial prion disease with a novel mutation in the PRNP gene. Archives of Neurology. 63: 1016-21. PMID 16831973 DOI: 10.1001/Archneur.63.7.1016  0.629
2006 Kaneko S, Kawarai T, Yip E, Salehi-Rad S, Sato C, Orlacchio A, Bernardi G, Liang Y, Hasegawa H, Rogaeva E, St George-Hyslop P. Novel SPG6 mutation p.A100T in a Japanese family with autosomal dominant form of hereditary spastic paraplegia. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 1531-3. PMID 16795073 DOI: 10.1002/Mds.21005  0.582
2006 Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, et al. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 440: 1208-12. PMID 16641999 DOI: 10.1038/Nature04667  0.492
2006 Zadikoff C, Rogaeva E, Djarmati A, Sato C, Salehi-Rad S, St George-Hyslop P, Klein C, Lang AE. Homozygous and heterozygous PINK1 mutations: considerations for diagnosis and care of Parkinson's disease patients. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 875-9. PMID 16547921 DOI: 10.1002/Mds.20854  0.578
2006 Munhoz RP, Kawarai T, Teive HA, Raskin S, Sato C, Liang Y, St George-Hyslop PH, Rogaeva E. Clinical and genetic study of a Brazilian family with spastic paraplegia (SPG6 locus). Movement Disorders : Official Journal of the Movement Disorder Society. 21: 279-81. PMID 16267846 DOI: 10.1002/Mds.20775  0.59
2006 Shibata N, Kawarai T, Lee JH, Lee HS, Shibata E, Sato C, Liang Y, Duara R, Mayeux RP, St George-Hyslop PH, Rogaeva E. Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease. Neuroscience Letters. 391: 142-6. PMID 16157450 DOI: 10.1016/J.Neulet.2005.08.048  0.604
2006 Bernardi L, Maletta RG, Tomaino C, Smirne N, Di Natale M, Perri M, Longo T, Colao R, Curcio SA, Puccio G, Mirabelli M, Kawarai T, Rogaeva E, St George Hyslop PH, Passarino G, et al. The effects of APOE and tau gene variability on risk of frontotemporal dementia. Neurobiology of Aging. 27: 702-9. PMID 15904995 DOI: 10.1016/J.Neurobiolaging.2005.03.008  0.418
2006 Guerreiro RJ, Bras JM, Santana I, Santiago B, Ribeiro MH, Momeni P, Rogaeva E, Oliveira C, Hardy J. P1-349: Genetic analysis of Portuguese patients with Alzheimer's disease and frontotemporal dementia Alzheimer's & Dementia. 2: S199-S200. DOI: 10.1016/J.Jalz.2006.05.727  0.437
2006 Santana I, Sá A, Guerreiro R, Brás J, Hardy J, Rogaeva E, Oliveira C. P1-348: Early onset familial Alzheimer's disease: First Portuguese cases Alzheimer's & Dementia. 2: S199-S199. DOI: 10.1016/J.Jalz.2006.05.726  0.426
2006 Lee JH, Lee H, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M, Tycko B, Rogaeva E, St. George-Hyslop P, Stern Y, Mayeux R. P1-304: Fine mapping of 12p for memory traits: A complementary approach to understanding the genetics of Alzheimer's disease Alzheimer's & Dementia. 2: S185-S186. DOI: 10.1016/J.Jalz.2006.05.682  0.337
2006 Rogaeva E, Goto J, Takahashi Y, Seki N, Wakutani Y, Meng Y, Lee J, Erlich P, Cheng R, Lee H, Sato C, Mayeux R, Farrer LA, George-Hyslop PS, Tsuji S. P3-171: Genetic analysis of LRRK2 in parkinson disease and Alzheimer disease datasets Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1439  0.422
2005 Paisán-Ruíz C, Lang AE, Kawarai T, Sato C, Salehi-Rad S, Fisman GK, Al-Khairallah T, St George-Hyslop P, Singleton A, Rogaeva E. LRRK2 gene in Parkinson disease: mutation analysis and case control association study. Neurology. 65: 696-700. PMID 16157901 DOI: 10.1212/01.wnl.0000167552.79769.b3  0.533
2005 Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, Hasegawa H, Salehi-Rad S, Wang L, Rogaeva E, Fraser P, Robinson B, St George-Hyslop P, et al. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. The Journal of Biological Chemistry. 280: 34025-32. PMID 16079129 DOI: 10.1074/Jbc.M505143200  0.541
2005 Moonis M, Swearer JM, Dayaw MP, St George-Hyslop P, Rogaeva E, Kawarai T, Pollen DA. Familial Alzheimer disease: decreases in CSF Abeta42 levels precede cognitive decline. Neurology. 65: 323-5. PMID 16043812 DOI: 10.1212/01.wnl.0000171397.32851.bc  0.531
2005 Edwards-Lee T, Ringman JM, Chung J, Werner J, Morgan A, St George Hyslop P, Thompson P, Dutton R, Mlikotic A, Rogaeva E, Hardy J. An African American family with early-onset Alzheimer disease and an APP (T714I) mutation. Neurology. 64: 377-9. PMID 15668448 DOI: 10.1212/01.Wnl.0000149761.70566.3E  0.453
2005 Sato C, Morgan A, Lang AE, Salehi-Rad S, Kawarai T, Meng Y, Ray PN, Farrer LA, St George-Hyslop P, Rogaeva E. Analysis of the glucocerebrosidase gene in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 367-70. PMID 15517592 DOI: 10.1002/Mds.20319  0.554
2004 Rogaeva E, Johnson J, Lang AE, Gulick C, Gwinn-Hardy K, Kawarai T, Sato C, Morgan A, Werner J, Nussbaum R, Petit A, Okun MS, McInerney A, Mandel R, Groen JL, et al. Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. Archives of Neurology. 61: 1898-904. PMID 15596610 DOI: 10.1001/Archneur.61.12.1898  0.572
2004 Klünemann HH, Rogaeva E, Neumann M, Kretzschmar HA, Kandel M, Toulina A, Sato C, Salehi-Rad S, Pfister K, Klein HE, St George-Hyslop PH. Novel PS1 mutation in a Bavarian kindred with familial Alzheimer disease. Alzheimer Disease and Associated Disorders. 18: 256-8. PMID 15592140  0.557
2004 Groen JL, Kawarai T, Toulina A, Rivoiro C, Salehi-Rad S, Sato C, Morgan A, Liang Y, Postuma RB, St George-Hyslop P, Lang AE, Rogaeva E. Genetic association study of PINK1 coding polymorphisms in Parkinson's disease. Neuroscience Letters. 372: 226-9. PMID 15542245 DOI: 10.1016/J.Neulet.2004.09.043  0.551
2004 Luis CA, Barker WW, Loewenstein DA, Crum TA, Rogaeva E, Kawarai T, St George-Hyslop P, Duara R. Conversion to dementia among two groups with cognitive impairment. A preliminary report. Dementia and Geriatric Cognitive Disorders. 18: 307-13. PMID 15305108 DOI: 10.1159/000080124  0.556
2004 Lee JH, Mayeux R, Mayo D, Mo J, Santana V, Williamson J, Flaquer A, Ciappa A, Rondon H, Estevez P, Lantigua R, Kawarai T, Toulina A, Medrano M, Torres M, ... ... Rogaeva E, et al. Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics. Molecular Psychiatry. 9: 1042-51. PMID 15241431 DOI: 10.1038/Sj.Mp.4001538  0.513
2004 Johnson J, Ostojic J, Lannfelt L, Glaser A, Basun H, Rogaeva E, Kawarai T, Bruni A, St George Hyslop PH, Goate A, Pastor P, Chakraverty S, Norton J, Morris JC, Hardy J, et al. No evidence for tau duplications in frontal temporal dementia families showing genetic linkage to the tau locus in which tau mutations have not been found. Neuroscience Letters. 363: 99-101. PMID 15172093 DOI: 10.1016/J.Neulet.2004.03.070  0.438
2004 Orlacchio A, Kawarai T, Polidoro M, Paterson AD, Rogaeva E, Orlacchio A, St George-Hyslop PH, Bernardi G. Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene. Neuroscience Letters. 363: 49-53. PMID 15157994 DOI: 10.1016/J.Neulet.2004.03.044  0.603
2004 Munhoz RP, Sa DS, Rogaeva E, Salehi-Rad S, Sato C, Medeiros H, Farrer M, Lang AE. Clinical findings in a large family with a parkin ex3delta40 mutation. Archives of Neurology. 61: 701-4. PMID 15148147 DOI: 10.1001/Archneur.61.5.701  0.401
2004 Orlacchio A, Kawarai T, Polidoro M, Paterson AD, Rogaeva E, Orlacchio A, St George-Hyslop PH, Bernardi G. P4-115 Molecular analysis of the nicastrin promoter SNPS in Alzheimer's disease Neurobiology of Aging. 25: S507-S508. DOI: 10.1016/S0197-4580(04)81673-7  0.401
2004 Cui J, Mukherjee P, Thompson H, Prescott S, Carlson M, Sato C, Salehi-Rad S, Rogaeva E, St George-Hyslop P, Farrer L, Moliaka Y, Grigorenko A, Rogaev E, Bazan N, Lukiw W. P4-076 Polymorphism in the cyclooxygenase-2 (COX-2) and presenilin 2 (PS2) gene promoters: impact on inflammatory signaling and potential contribution to the etiopathology of Alzheimer's disease (AD) Neurobiology of Aging. 25: S495-S496. DOI: 10.1016/S0197-4580(04)81634-8  0.311
2004 Rogaeva E, Meng Y, Toulina A, Shibata N, Kawarai T, Sato C, Salehi-Rad S, Morgan A, Rivoiro C, Liang Y, Sorbi S, Bruni AC, Oene MV, Lee J, Mayeux R, et al. S2-01-03 Genetic studies in late-onset Alzheimer disease: loci on chromosomes 12 and 10 Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80081-2  0.414
2003 Rogaeva E, Bergeron C, Sato C, Moliaka I, Kawarai T, Toulina A, Song YQ, Kolesnikova T, Orlacchio A, Bernardi G, St George-Hyslop PH. PS1 Alzheimer's disease family with spastic paraplegia: the search for a gene modifier. Neurology. 61: 1005-7. PMID 14557582 DOI: 10.1212/Wnl.61.7.1005  0.653
2003 Hague S, Rogaeva E, Hernandez D, Gulick C, Singleton A, Hanson M, Johnson J, Weiser R, Gallardo M, Ravina B, Gwinn-Hardy K, Crawley A, St George-Hyslop PH, Lang AE, Heutink P, et al. Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation. Annals of Neurology. 54: 271-4. PMID 12891685 DOI: 10.1002/Ana.10663  0.564
2003 Kleiner-Fisman G, Rogaeva E, Halliday W, Houle S, Kawarai T, Sato C, Medeiros H, St George-Hyslop PH, Lang AE. Benign hereditary chorea: clinical, genetic, and pathological findings. Annals of Neurology. 54: 244-7. PMID 12891678 DOI: 10.1002/Ana.10637  0.583
2003 Tandon A, Yu H, Wang L, Rogaeva E, Sato C, Chishti MA, Kawarai T, Hasegawa H, Chen F, Davies P, Fraser PE, Westaway D, St George-Hyslop PH. Brain levels of CDK5 activator p25 are not increased in Alzheimer's or other neurodegenerative diseases with neurofibrillary tangles. Journal of Neurochemistry. 86: 572-81. PMID 12859671 DOI: 10.1046/J.1471-4159.2003.01865.X  0.554
2003 Lincoln S, Wiley J, Lynch T, Langston JW, Chen R, Lang A, Rogaeva E, Sa DS, Munhoz RP, Harris J, Marder K, Klein C, Bisceglio G, Hussey J, West A, et al. Parkin-proven disease: common founders but divergent phenotypes. Neurology. 60: 1605-10. PMID 12771249 DOI: 10.1212/01.Wnl.0000064289.49410.A9  0.313
2003 Di Natale M, Perri M, Kawarai T, Maletta R, Tomaino C, Sato C, Nacmias B, Shibata N, Sorbi S, St George-Hyslop PH, Bruni AC, Rogaeva E. Absence of association between Alzheimer disease and the regulatory region polymorphism of the PS2 gene in an Italian population. Neuroscience Letters. 343: 210-2. PMID 12770698 DOI: 10.1016/S0304-3940(03)00335-5  0.615
2002 Orlacchio A, Kawarai T, Rogaeva E, Song YQ, Paterson AD, Bernardi G, St George-Hyslop PH. Clinical and genetic study of a large Italian family linked to SPG12 locus. Neurology. 59: 1395-401. PMID 12427890 DOI: 10.1212/01.Wnl.0000031423.43482.19  0.517
2002 Rogaeva E. The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease. Neuromolecular Medicine. 2: 1-10. PMID 12230301 DOI: 10.1385/Nmm:2:1:01  0.481
2001 Rogaeva E, Tandon A, St George-Hyslop PH. Genetic markers in the diagnosis of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 3: 293-304. PMID 12214050 DOI: 10.3233/Jad-2001-3304  0.627
2001 Nicolaou M, Song YQ, Sato CA, Orlacchio A, Kawarai T, Medeiros H, Liang Y, Sorbi S, Richard E, Rogaev EI, Moliaka Y, Bruni AC, Jorge R, Percy M, Duara R, ... ... Rogaeva EA, et al. Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease. Neurogenetics. 3: 203-6. PMID 11714100 DOI: 10.1007/S100480100123  0.352
2001 Athan ES, Williamson J, Ciappa A, Santana V, Romas SN, Lee JH, Rondon H, Lantigua RA, Medrano M, Torres M, Arawaka S, Rogaeva E, Song YQ, Sato C, Kawarai T, et al. A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families. Jama. 286: 2257-63. PMID 11710891 DOI: 10.1001/Jama.286.18.2257  0.645
2001 Rogaeva EA, Fafel KC, Song YQ, Medeiros H, Sato C, Liang Y, Richard E, Rogaev EI, Frommelt P, Sadovnick AD, Meschino W, Rockwood K, Boss MA, Mayeux R, St George-Hyslop P. Screening for PS1 mutations in a referral-based series of AD cases: 21 novel mutations. Neurology. 57: 621-5. PMID 11524469 DOI: 10.1212/WNL.57.4.621  0.573
2001 Chen F, Yu G, Arawaka S, Nishimura M, Kawarai T, Yu H, Tandon A, Supala A, Song YQ, Rogaeva E, Milman P, Sato C, Yu C, Janus C, Lee J, et al. Nicastrin binds to membrane-tethered Notch. Nature Cell Biology. 3: 751-4. PMID 11483961 DOI: 10.1038/35087069  0.528
2000 Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser P, Haass C, et al. Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes. Acta Neurologica Scandinavica. Supplementum. 176: 6-11. PMID 11261807 DOI: 10.1034/J.1600-0404.2000.00301.X  0.492
2000 Zhang DM, Levitan D, Yu G, Nishimura M, Chen F, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Liang Y, Holmes E, Milman P, Sato C, et al. Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans. Neuroreport. 11: 3227-30. PMID 11043553 DOI: 10.1097/00001756-200009280-00035  0.484
2000 Devi G, Fotiou A, Jyrinji D, Tycko B, DeArmand S, Rogaeva E, Song YQ, Medieros H, Liang Y, Orlacchio A, Williamson J, St George-Hyslop P, Mayeux R. Novel presenilin 1 mutations associated with early onset of dementia in a family with both early-onset and late-onset Alzheimer disease. Archives of Neurology. 57: 1454-7. PMID 11030797 DOI: 10.1001/Archneur.57.10.1454  0.642
2000 Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, et al. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 407: 48-54. PMID 10993067 DOI: 10.1038/35024009  0.502
2000 Tandon A, Rogaeva E, Mullan M, St George-Hyslop PH. Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Current Opinion in Neurology. 13: 377-84. PMID 10970053 DOI: 10.1097/00019052-200008000-00003  0.585
2000 Chen F, Yang DS, Petanceska S, Yang A, Tandon A, Yu G, Rozmahel R, Ghiso J, Nishimura M, Zhang DM, Kawarai T, Levesque G, Mills J, Levesque L, Song YQ, ... Rogaeva E, et al. Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells. The Journal of Biological Chemistry. 275: 36794-802. PMID 10962005 DOI: 10.1074/Jbc.M006986200  0.51
2000 Jorge R, Mangone C, Castano E, Perandones C, Rogaeva E, St George-Hyslop P, El Hachimi KH, Foncin JF, Robinson RG, Bruni AC. Comparison of clinical and pathological phenotypes in two ethnically and geographically unrelated pedigrees segregating an equivalent presenilin 1 mutation. The Journal of Neuropsychiatry and Clinical Neurosciences. 12: 359-63. PMID 10956569 DOI: 10.1176/Jnp.12.3.359  0.611
2000 Fraser PE, Yang DS, Yu G, Lévesque L, Nishimura M, Arawaka S, Serpell LC, Rogaeva E, St George-Hyslop P. Presenilin structure, function and role in Alzheimer disease. Biochimica Et Biophysica Acta. 1502: 1-15. PMID 10899427 DOI: 10.1016/S0925-4439(00)00028-4  0.603
2000 Kertesz A, Kawarai T, Rogaeva E, St George-Hyslop P, Poorkaj P, Bird TD, Munoz DG. Familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions. Neurology. 54: 818-27. PMID 10690970 DOI: 10.1212/Wnl.54.4.818  0.617
2000 Farrer LA, Sherbatich T, Keryanov SA, Korovaitseva GI, Rogaeva EA, Petruk S, Premkumar S, Moliaka Y, Song YQ, Pei Y, Sato C, Selezneva ND, Voskresenskaya S, Golimbet V, Sorbi S, et al. Association between angiotensin-converting enzyme and Alzheimer disease. Archives of Neurology. 57: 210-4. PMID 10681079 DOI: 10.1001/Archneur.57.2.210  0.519
1999 Romero I, Jørgensen P, Bolwig G, Fraser PE, Rogaeva E, Mann D, Havsager AM, Jørgensen AL. A presenilin-1 Thr116Asn substitution in a family with early-onset Alzheimer's disease. Neuroreport. 10: 2255-60. PMID 10439444 DOI: 10.1097/00001756-199908020-00006  0.51
1999 De Jonghe C, Cruts M, Rogaeva EA, Tysoe C, Singleton A, Vanderstichele H, Meschino W, Dermaut B, Vanderhoeven I, Backhovens H, Vanmechelen E, Morris CM, Hardy J, Rubinsztein DC, St George-Hyslop PH, et al. Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased Abeta42 secretion. Human Molecular Genetics. 8: 1529-40. PMID 10401002 DOI: 10.1093/Hmg/8.8.1529  0.612
1999 Rogaeva EA, Premkumar S, Grubber J, Serneels L, Scott WK, Kawarai T, Song Y, Hill DL, Abou-Donia SM, Martin ER, Vance JJ, Yu G, Orlacchio A, Pei Y, Nishimura M, et al. An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nature Genetics. 22: 19-22. PMID 10319855 DOI: 10.1038/8729  0.554
1999 Levesque G, Yu G, Nishimura M, Zhang DM, Levesque L, Yu H, Xu D, Liang Y, Rogaeva E, Ikeda M, Duthie M, Murgolo N, Wang L, VanderVere P, Bayne ML, et al. Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin. Journal of Neurochemistry. 72: 999-1008. PMID 10037471 DOI: 10.1046/J.1471-4159.1999.0720999.X  0.532
1999 Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, et al. Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex. Nature Medicine. 5: 164-9. PMID 9930863 DOI: 10.1038/5526  0.566
1998 Farrer LA, Abraham CR, Haines JL, Rogaeva EA, Song Y, McGraw WT, Brindle N, Premkumar S, Scott WK, Yamaoka LH, Saunders AM, Roses AD, Auerbach SA, Sorbi S, Duara R, et al. Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Annals of Neurology. 44: 808-11. PMID 9818937 DOI: 10.1002/Ana.410440515  0.551
1998 Rogaeva E, Premkumar S, Song Y, Sorbi S, Brindle N, Paterson A, Duara R, Levesque G, Yu G, Nishimura M, Ikeda M, O'Toole C, Kawarai T, Jorge R, Vilarino D, et al. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity. Jama. 280: 614-8. PMID 9718052 DOI: 10.1001/Jama.280.7.614  0.598
1998 Song YQ, Rogaeva E, Premkumar S, Brindle N, Kawarai T, Orlacchio A, Yu G, Levesque G, Nishimura M, Ikeda M, Pei Y, O'Toole C, Duara R, Barker W, Sorbi S, et al. Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neuroscience Letters. 250: 189-92. PMID 9708864 DOI: 10.1016/S0304-3940(98)00470-4  0.594
1998 Yu G, Chen F, Levesque G, Nishimura M, Zhang DM, Levesque L, Rogaeva E, Xu D, Liang Y, Duthie M, St George-Hyslop PH, Fraser PE. The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin. The Journal of Biological Chemistry. 273: 16470-5. PMID 9632714 DOI: 10.1074/Jbc.273.26.16470  0.502
1998 Tamaoka A, Fraser PE, Ishii K, Sahara N, Ozawa K, Ikeda M, Saunders AM, Komatsuzaki Y, Sherrington R, Levesque G, Yu G, Rogaeva E, Shoji S, Nee LE, Pollen DA, et al. Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease. Brain Research. Molecular Brain Research. 56: 178-85. PMID 9602117 DOI: 10.1016/S0169-328X(98)00044-8  0.568
1998 Brindle N, Song Y, Rogaeva E, Premkumar S, Levesque G, Yu G, Ikeda M, Nishimura M, Paterson A, Sorbi S, Duara R, Farrer L, St George-Hyslop P. Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease. Human Molecular Genetics. 7: 933-5. PMID 9536099 DOI: 10.1093/Hmg/7.5.933  0.612
1997 Rogaev EI, Sherrington R, Wu C, Levesque G, Liang Y, Rogaeva EA, Ikeda M, Holman K, Lin C, Lukiw WJ, de Jong PJ, Fraser PE, Rommens JM, St George-Hyslop P. Analysis of the 5' sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer disease. Genomics. 40: 415-24. PMID 9073509 DOI: 10.1006/Geno.1996.4523  0.496
1996 Ikeda M, Sharma V, Sumi SM, Rogaeva EA, Poorkaj P, Sherrington R, Nee L, Tsuda T, Oda N, Watanabe M, Aoki M, Shoji M, Abe K, Itoyama Y, Hirai S, et al. The clinical phenotype of two missense mutations in the presenilin I gene in Japanese patients. Annals of Neurology. 40: 912-7. PMID 9007097 DOI: 10.1002/Ana.410400614  0.596
1996 Sherrington R, Froelich S, Sorbi S, Campion D, Chi H, Rogaeva EA, Levesque G, Rogaev EI, Lin C, Liang Y, Ikeda M, Mar L, Brice A, Agid Y, Percy ME, et al. Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant. Human Molecular Genetics. 5: 985-8. PMID 8817335 DOI: 10.1093/Hmg/5.7.985  0.591
1996 Igarashi S, Takiyama Y, Cancel G, Rogaeva EA, Sasaki H, Wakisaka A, Zhou YX, Takano H, Endo K, Sanpei K, Oyake M, Tanaka H, Stevanin G, Abbas N, Dürr A, et al. Intergenerational instability of the CAG repeat of the gene for Machado-Joseph disease (MJD1) is affected by the genotype of the normal chromosome: implications for the molecular mechanisms of the instability of the CAG repeat. Human Molecular Genetics. 5: 923-32. PMID 8817326 DOI: 10.1093/Hmg/5.7.923  0.435
1996 Rogaev EI, Rogaeva EA, Korovaitseva GI, Farrer LA, Petrin AN, Keryanov SA, Turaeva S, Chumakov I, St George-Hyslop P, Ginter EK. Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35. Human Molecular Genetics. 5: 699-703. PMID 8733140 DOI: 10.1093/hmg/5.5.699  0.519
1996 George-Hyslop PS, Rogaev EI, Sherrington R, Rogaeva EA, Rogaeva G, Levesque G, Ikeda M, Liang Y, Chi H, Lin C, Holman K, Fraser PE, Rommens JM. Two homologous genes associated with early onset familial Alzheimer's disease Biological Psychiatry. 39: 562. DOI: 10.1016/0006-3223(96)84160-6  0.301
1995 Tsuda T, Chi H, Liang Y, Rogaeva EA, Sherrington R, Levesque G, Ikeda M, Rogaev EI, Pollen D, Freedman M. Failure to detect missense mutations in the S182 gene in a series of late-onset Alzheimer's disease cases. Neuroscience Letters. 201: 188-90. PMID 8848249 DOI: 10.1016/0304-3940(95)12170-6  0.414
1995 Rogaev EI, Sherrington R, Rogaeva EA, Levesque G, Ikeda M, Liang Y, Chi H, Lin C, Holman K, Tsuda T, Mar L, Sorbi S, Nacmias B, Piacentini S, Amaducci L, et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene Nature. 376: 775-778. PMID 7651536 DOI: 10.1038/376775A0  0.36
1995 Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375: 754-60. PMID 7596406 DOI: 10.1038/375754A0  0.615
1995 Tuite PJ, Rogaeva EA, St George-Hyslop PH, Lang AE. Dopa-responsive parkinsonism phenotype of Machado-Joseph disease: confirmation of 14q CAG expansion. Annals of Neurology. 38: 684-7. PMID 7574470 DOI: 10.1002/ana.410380422  0.525
1994 Lang AE, Rogaeva EA, Tsuda T, Hutterer J, St George-Hyslop P. Homozygous inheritance of the Machado-Joseph disease gene. Annals of Neurology. 36: 443-7. PMID 8080254 DOI: 10.1002/ana.410360318  0.525
1994 Tsuda T, Lopez R, Rogaeva EA, Freedman M, Rogaev E, Drachman D, Pollen D, Haines J, Liang Y, McLachlan DR. Are the associations between Alzheimer's disease and polymorphisms in the apolipoprotein E and the apolipoprotein CII genes due to linkage disequilibrium? Annals of Neurology. 36: 97-100. PMID 8024269 DOI: 10.1002/Ana.410360118  0.329
1993 Tupler R, Rogaeva E, Vaula G, Mortilla M, Lukiw W, Liang Y, Hancock R, Rogaev E, St George-Hyslop P. A highly informative microsatellite repeat polymorphism in intron 1 of the human amyloid precursor protein (APP) gene. Human Molecular Genetics. 2: 620. PMID 8518820 DOI: 10.1093/Hmg/2.5.620  0.544
1993 Wong L, Liang Y, Jiang L, Tsuda T, Fong Q, Galway G, Alexandrova N, Rogaeva E, Lukiw W, Smith J, Rogaev E, Mclachlan DC, George-Hyslop PS. Mutation of the gene for the human lysosomal serine protease cathepsin G is not the cause of aberrant APP processing in familial Alzheimer disease. Neuroscience Letters. 152: 96-98. PMID 8515885 DOI: 10.1016/0304-3940(93)90492-4  0.436
1993 Rogaev EI, Lukiw WJ, Vaula G, Haines JL, Rogaeva EA, Tsuda T, Alexandrova N, Liang Y, Mortilla M, Amaducci L, Bergamini L, Bruni AC, Foncin JF, Macciardi F, Montesi M, et al. Analysis of the c-FOS gene on chromosome 14 and the promoter of the amyloid precursor protein gene in familial Alzheimer's disease. Neurology. 43: 2275-9. PMID 8232942 DOI: 10.1212/Wnl.43.11.2275  0.53
1993 Rogaev EI, Rogaeva EA, Ginter EK, Korovaitseva GI, Farrer LA, Shlensky AB, Pritkov AN, Mordovtsev VN, St George-Hyslop PH. Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes. Nature Genetics. 5: 158-62. PMID 7504553 DOI: 10.1038/ng1093-158  0.521
1992 St George-Hyslop P, Haines J, Rogaev E, Mortilla M, Vaula G, Pericak-Vance M, Foncin JF, Montesi M, Bruni A, Sorbi S, Rainero I, Pinessi L, Pollen D, Polinsky R, Nee L, ... ... Rogaeva E, et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nature Genetics. 2: 330-4. PMID 1303289 DOI: 10.1038/Ng1292-330  0.448
1992 Rogaev E, Rogaeva E, Lukiw WJ, Vaula G, Liang Y, Hancock R, McLachlan DC, St George-Hyslop PH. An informative microsatellite repeat polymorphism in the human neurofilament light polypeptide (NEFL) gene. Human Molecular Genetics. 1: 781. PMID 1302625 DOI: 10.1093/Hmg/1.9.781  0.495
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