| Year |
Citation |
Score |
| 2024 |
Grande D, Rajendra E, Mason B, Galbiati A, Boulton SJ, Smith GCM, Robinson HMR. Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-based Reporter Assays. Journal of Visualized Experiments : Jove. PMID 38949387 DOI: 10.3791/66969 |
0.437 |
|
| 2023 |
Rajendra E, Grande D, Mason B, Di Marcantonio D, Armstrong L, Hewitt G, Elinati E, Galbiati A, Boulton SJ, Heald RA, Smith GCM, Robinson HMR. Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells. Nucleic Acids Research. PMID 38109306 DOI: 10.1093/nar/gkad1196 |
0.449 |
|
| 2023 |
Newton MD, Losito M, Smith QM, Parnandi N, Taylor BJ, Akcakaya P, Maresca M, van Eijk P, Reed SH, Boulton SJ, King GA, Cuomo ME, Rueda DS. Negative DNA supercoiling induces genome-wide Cas9 off-target activity. Molecular Cell. 83: 3533-3545.e5. PMID 37802026 DOI: 10.1016/j.molcel.2023.09.008 |
0.367 |
|
| 2023 |
Belan O, Greenhough L, Kuhlen L, Anand R, Kaczmarczyk A, Gruszka DT, Yardimci H, Zhang X, Rueda DS, West SC, Boulton SJ. Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein. Molecular Cell. PMID 37499663 DOI: 10.1016/j.molcel.2023.06.031 |
0.448 |
|
| 2023 |
Greenhough LA, Liang CC, Belan O, Kunzelmann S, Maslen S, Rodrigo-Brenni MC, Anand R, Skehel M, Boulton SJ, West SC. Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. Nature. PMID 37344587 DOI: 10.1038/s41586-023-06179-1 |
0.437 |
|
| 2023 |
Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcalá K, Ball K, Proctor B, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, ... ... Boulton SJ, et al. The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining. Molecular Cell. PMID 37044098 DOI: 10.1016/j.molcel.2023.03.017 |
0.454 |
|
| 2023 |
Schimmel J, Muñoz-Subirana N, Kool H, van Schendel R, van der Vlies S, Kamp JA, de Vrij F, Kushner SA, Smith GCM, Boulton SJ, Tijsterman M. Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways. Cell Reports. 42: 112019. PMID 36701230 DOI: 10.1016/j.celrep.2023.112019 |
0.343 |
|
| 2022 |
Belan O, Sebald M, Adamowicz M, Anand R, Vancevska A, Neves J, Grinkevich V, Hewitt G, Segura-Bayona S, Bellelli R, Robinson HMR, Higgins GS, Smith GCM, West SC, Rueda DS, ... Boulton SJ, et al. POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells. Molecular Cell. PMID 36455556 DOI: 10.1016/j.molcel.2022.11.008 |
0.329 |
|
| 2022 |
Borel V, Boeing S, Van Wietmarschen N, Sridharan S, Hill BR, Ombrato L, Perez-Lloret J, Jackson D, Goldstone R, Boulton SJ, Nussenzweig A, Bellelli R. Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis. Cell Reports. 39: 110871. PMID 35649380 DOI: 10.1016/j.celrep.2022.110871 |
0.312 |
|
| 2022 |
Bayley R, Borel V, Moss RJ, Sweatman E, Ruis P, Ormrod A, Goula A, Mottram RMA, Stanage T, Hewitt G, Saponaro M, Stewart GS, Boulton SJ, Higgs MR. H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ. Molecular Cell. PMID 35439434 DOI: 10.1016/j.molcel.2022.03.030 |
0.429 |
|
| 2022 |
Silva N, Castellano-Pozo M, Matsuzaki K, Barroso C, Roman-Trufero M, Craig H, Brooks DR, Isaac RE, Boulton SJ, Martinez-Perez E. Proline-specific aminopeptidase P prevents replication-associated genome instability. Plos Genetics. 18: e1010025. PMID 35081133 DOI: 10.1371/journal.pgen.1010025 |
0.436 |
|
| 2021 |
Anand R, Buechelmaier E, Belan O, Newton M, Vancevska A, Kaczmarczyk A, Takaki T, Rueda DS, Powell SN, Boulton SJ. HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51. Nature. PMID 34937945 DOI: 10.1038/s41586-021-04261-0 |
0.496 |
|
| 2021 |
Špírek M, Taylor MRG, Belan O, Boulton SJ, Krejci L. Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function. Nature Communications. 12: 5545. PMID 34545070 DOI: 10.1038/s41467-021-25830-x |
0.33 |
|
| 2021 |
Bacic L, Gaullier G, Sabantsev A, Lehmann LC, Brackmann K, Dimakou D, Halic M, Hewitt G, Boulton S, Deindl S. Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome. Elife. 10. PMID 34486521 DOI: 10.7554/eLife.71420 |
0.382 |
|
| 2021 |
Chapman JR, Barral P, Vannier JB, Borel V, Steger M, Tomas-Loba A, Sartori AA, Adams IR, Batista FD, Boulton SJ. RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection. Molecular Cell. 81: 2868. PMID 34214445 DOI: 10.1016/j.molcel.2021.06.015 |
0.41 |
|
| 2021 |
Belan O, Anand R, Boulton SJ. Mechanism of mitotic recombination: insights from C. elegans. Current Opinion in Genetics & Development. 71: 10-18. PMID 34186335 DOI: 10.1016/j.gde.2021.06.005 |
0.439 |
|
| 2021 |
Zatreanu D, Robinson HMR, Alkhatib O, Boursier M, Finch H, Geo L, Grande D, Grinkevich V, Heald RA, Langdon S, Majithiya J, McWhirter C, Martin NMB, Moore S, Neves J, ... ... Boulton SJ, et al. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nature Communications. 12: 3636. PMID 34140467 DOI: 10.1038/s41467-021-23463-8 |
0.41 |
|
| 2021 |
Meier B, Volkova NV, Hong Y, Bertolini S, González-Huici V, Petrova T, Boulton S, Campbell PJ, Gerstung M, Gartner A. Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation. Plos One. 16: e0250291. PMID 33905417 DOI: 10.1371/journal.pone.0250291 |
0.402 |
|
| 2021 |
Belan O, Barroso C, Kaczmarczyk A, Anand R, Federico S, O'Reilly N, Newton MD, Maeots E, Enchev RI, Martinez-Perez E, Rueda DS, Boulton SJ. Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins. Molecular Cell. PMID 33421363 DOI: 10.1016/j.molcel.2020.12.020 |
0.398 |
|
| 2021 |
Bellelli R, Boulton SJ. Spotlight on the Replisome: Aetiology of DNA Replication-Associated Genetic Diseases. Trends in Genetics : Tig. 37: 317-336. PMID 33041047 DOI: 10.1016/j.tig.2020.09.008 |
0.38 |
|
| 2020 |
Kotsantis P, Segura-Bayona S, Margalef P, Marzec P, Ruis P, Hewitt G, Bellelli R, Patel H, Goldstone R, Poetsch AR, Boulton SJ. RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions. Cell Reports. 33: 108546. PMID 33357438 DOI: 10.1016/j.celrep.2020.108546 |
0.381 |
|
| 2020 |
Lehmann LC, Bacic L, Hewitt G, Brackmann K, Sabantsev A, Gaullier G, Pytharopoulou S, Degliesposti G, Okkenhaug H, Tan S, Costa A, Skehel JM, Boulton SJ, Deindl S. Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch. Cell Reports. 33: 108529. PMID 33357431 DOI: 10.1016/j.celrep.2020.108529 |
0.335 |
|
| 2020 |
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, ... ... Boulton SJ, et al. Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Molecular Cell. PMID 33333017 DOI: 10.1016/j.molcel.2020.12.006 |
0.729 |
|
| 2020 |
Xue C, Molnarova L, Steinfeld JB, Zhao W, Ma C, Spirek M, Kaniecki K, Kwon Y, Beláň O, Krejci K, Boulton SJ, Sung P, Greene EC, Krejci L. Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates. Nucleic Acids Research. PMID 33332547 DOI: 10.1093/nar/gkaa1184 |
0.495 |
|
| 2020 |
Ruis P, Van Ly D, Borel V, Kafer GR, McCarthy A, Howell S, Blassberg R, Snijders AP, Briscoe J, Niakan KK, Marzec P, Cesare AJ, Boulton SJ. TRF2-independent chromosome end protection during pluripotency. Nature. PMID 33239783 DOI: 10.1038/s41586-020-2960-y |
0.32 |
|
| 2020 |
Segura-Bayona S, Villamor-Payà M, Attolini CS, Koenig LM, Sanchiz-Calvo M, Boulton SJ, Stracker TH. Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres. Cell Reports. 32: 107983. PMID 32755577 DOI: 10.1016/j.celrep.2020.107983 |
0.309 |
|
| 2020 |
Bellelli R, Youds J, Borel V, Svendsen J, Pavicic-Kaltenbrunner V, Boulton SJ. Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication. Cell Reports. 31: 107675. PMID 32460026 DOI: 10.1016/J.Celrep.2020.107675 |
0.492 |
|
| 2020 |
Vančevska A, Ahmed W, Pfeiffer V, Feretzaki M, Boulton SJ, Lingner J. SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres. The Embo Journal. e102668. PMID 32080884 DOI: 10.15252/Embj.2019102668 |
0.441 |
|
| 2019 |
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ. CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. PMID 31723267 DOI: 10.1038/S41586-019-1744-8 |
0.353 |
|
| 2019 |
Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Solé L, González-Farré M, Alonso J, Montagut C, Martinez-Iniesta M, Bertran J, Borràs E, Iglesias M, Sabidó E, Bigas A, ... Boulton SJ, et al. IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Molecular Cell. PMID 31302002 DOI: 10.1016/j.molcel.2019.05.036 |
0.319 |
|
| 2019 |
Gourley C, Balmaña J, Ledermann JA, Serra V, Dent R, Loibl S, Pujade-Lauraine E, Boulton SJ. Moving From Poly (ADP-Ribose) Polymerase Inhibition to Targeting DNA Repair and DNA Damage Response in Cancer Therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1802050. PMID 31050911 DOI: 10.1200/JCO.18.02050 |
0.465 |
|
| 2019 |
Garcia-Muse T, Galindo-Diaz U, Garcia-Rubio M, Martin JS, Polanowska J, O'Reilly N, Aguilera A, Boulton SJ. A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs. Cell Reports. 26: 775-787.e5. PMID 30650366 DOI: 10.1016/j.celrep.2018.12.074 |
0.409 |
|
| 2018 |
Poetsch AR, Boulton SJ, Luscombe NM. Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis. Genome Biology. 19: 215. PMID 30526646 DOI: 10.1186/s13059-018-1582-2 |
0.456 |
|
| 2017 |
Lehmann LC, Hewitt G, Aibara S, Leitner A, Marklund E, Maslen SL, Maturi V, Chen Y, van der Spoel D, Skehel JM, Moustakas A, Boulton SJ, Deindl S. Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1. Molecular Cell. 68: 847-859.e7. PMID 29220652 DOI: 10.1016/J.Molcel.2017.10.017 |
0.42 |
|
| 2017 |
Stingele J, Bellelli R, Boulton SJ. Mechanisms of DNA-protein crosslink repair. Nature Reviews. Molecular Cell Biology. 18: 563-573. PMID 28655905 DOI: 10.1038/nrm.2017.56 |
0.531 |
|
| 2017 |
von Morgen P, Burdova K, Flower TG, O'Reilly NJ, Boulton SJ, Smerdon SJ, Macurek L, Hořejší Z. MRE11 stability is regulated by CK2-dependent interaction with R2TP complex. Oncogene. 36: 4943-4950. PMID 28436950 DOI: 10.1038/onc.2017.99 |
0.327 |
|
| 2017 |
Hiraga SI, Ly T, Garzón J, Hořejší Z, Ohkubo YN, Endo A, Obuse C, Boulton SJ, Lamond AI, Donaldson AD. Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. Embo Reports. PMID 28077461 DOI: 10.15252/Embr.201641983 |
0.426 |
|
| 2016 |
Stingele J, Bellelli R, Alte F, Hewitt G, Sarek G, Maslen SL, Tsutakawa SE, Borg A, Kjær S, Tainer JA, Skehel JM, Groll M, Boulton SJ. Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Molecular Cell. 64: 688-703. PMID 27871365 DOI: 10.1016/J.Molcel.2016.09.031 |
0.501 |
|
| 2016 |
Taylor MR, Špírek M, Jian Ma C, Carzaniga R, Takaki T, Collinson LM, Greene EC, Krejci L, Boulton SJ. A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling. Molecular Cell. PMID 27867009 DOI: 10.1016/J.Molcel.2016.10.020 |
0.349 |
|
| 2015 |
Matsuzaki K, Borel V, Adelman CA, Schindler D, Boulton SJ. FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway. Genes & Development. PMID 26637282 DOI: 10.1101/gad.272740.115 |
0.367 |
|
| 2015 |
Taylor MR, Špírek M, Chaurasiya KR, Ward JD, Carzaniga R, Yu X, Egelman EH, Collinson LM, Rueda D, Krejci L, Boulton SJ. Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination. Cell. 162: 271-86. PMID 26186187 DOI: 10.1016/J.Cell.2015.06.015 |
0.414 |
|
| 2015 |
Higgs MR, Reynolds JJ, Winczura A, Blackford AN, Borel V, Miller ES, Zlatanou A, Nieminuszczy J, Ryan EL, Davies NJ, Stankovic T, Boulton SJ, Niedzwiedz W, Stewart GS. BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks. Molecular Cell. 59: 462-77. PMID 26166705 DOI: 10.1016/j.molcel.2015.06.007 |
0.69 |
|
| 2015 |
Xu G, Chapman JR, Brandsma I, Yuan J, Mistrik M, Bouwman P, Bartkova J, Gogola E, Warmerdam D, Barazas M, Jaspers JE, Watanabe K, Pieterse M, Kersbergen A, Sol W, ... ... Boulton SJ, et al. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 521: 541-4. PMID 25799992 DOI: 10.1038/Nature14328 |
0.401 |
|
| 2015 |
Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD. Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature. 518: 258-62. PMID 25642963 DOI: 10.1038/Nature14184 |
0.496 |
|
| 2014 |
Staples CJ, Myers KN, Beveridge RD, Patil AA, Howard AE, Barone G, Lee AJ, Swanton C, Howell M, Maslen S, Skehel JM, Boulton SJ, Collis SJ. Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability. Journal of Cell Science. 127: 2910-9. PMID 24816561 DOI: 10.1242/Jcs.147785 |
0.453 |
|
| 2014 |
León-Ortiz AM, Svendsen J, Boulton SJ. Metabolism of DNA secondary structures at the eukaryotic replication fork. Dna Repair. 19: 152-162. PMID 24815912 DOI: 10.1016/J.Dnarep.2014.03.016 |
0.375 |
|
| 2014 |
Vannier JB, Sarek G, Boulton SJ. RTEL1: functions of a disease-associated helicase. Trends in Cell Biology. 24: 416-25. PMID 24582487 DOI: 10.1016/j.tcb.2014.01.004 |
0.403 |
|
| 2014 |
Panier S, Boulton SJ. Double-strand break repair: 53BP1 comes into focus. Nature Reviews. Molecular Cell Biology. 15: 7-18. PMID 24326623 DOI: 10.1038/Nrm3719 |
0.469 |
|
| 2013 |
Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H, Boulton SJ. RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science (New York, N.Y.). 342: 239-42. PMID 24115439 DOI: 10.1126/science.1241779 |
0.335 |
|
| 2013 |
Adelman CA, Lolo RL, Birkbak NJ, Murina O, Matsuzaki K, Horejsi Z, Parmar K, Borel V, Skehel JM, Stamp G, D'Andrea A, Sartori AA, Swanton C, Boulton SJ. HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature. 502: 381-4. PMID 24005329 DOI: 10.1038/Nature12565 |
0.501 |
|
| 2013 |
Kulkarni A, Oza J, Yao M, Sohail H, Ginjala V, Tomas-Loba A, Horejsi Z, Tan AR, Boulton SJ, Ganesan S. Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein. The Journal of Biological Chemistry. 288: 32357-69. PMID 23926104 DOI: 10.1074/jbc.M113.459164 |
0.524 |
|
| 2013 |
Chapman JR, Barral P, Vannier JB, Borel V, Steger M, Tomas-Loba A, Sartori AA, Adams IR, Batista FD, Boulton SJ. RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Molecular Cell. 49: 858-71. PMID 23333305 DOI: 10.1016/j.molcel.2013.01.002 |
0.417 |
|
| 2012 |
Chapman JR, Taylor MR, Boulton SJ. Playing the end game: DNA double-strand break repair pathway choice. Molecular Cell. 47: 497-510. PMID 22920291 DOI: 10.1016/j.molcel.2012.07.029 |
0.451 |
|
| 2012 |
Staples CJ, Myers KN, Beveridge RD, Patil AA, Lee AJ, Swanton C, Howell M, Boulton SJ, Collis SJ. The centriolar satellite protein Cep131 is important for genome stability. Journal of Cell Science. 125: 4770-9. PMID 22797915 DOI: 10.1242/Jcs.104059 |
0.349 |
|
| 2012 |
Vannier JB, Pavicic-Kaltenbrunner V, Petalcorin MI, Ding H, Boulton SJ. RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell. 149: 795-806. PMID 22579284 DOI: 10.1016/j.cell.2012.03.030 |
0.356 |
|
| 2012 |
Chapman JR, Sossick AJ, Boulton SJ, Jackson SP. BRCA1-associated exclusion of 53BP1 from DNA: Damage sites underlies temporal control of DNA repair Journal of Cell Science. 125: 3529-3534. PMID 22553214 DOI: 10.1242/jcs.105353 |
0.637 |
|
| 2012 |
Moldovan GL, Dejsuphong D, Petalcorin MI, Hofmann K, Takeda S, Boulton SJ, D'Andrea AD. Inhibition of homologous recombination by the PCNA-interacting protein PARI. Molecular Cell. 45: 75-86. PMID 22153967 DOI: 10.1016/J.Molcel.2011.11.010 |
0.474 |
|
| 2011 |
Youds JL, Boulton SJ. The choice in meiosis - defining the factors that influence crossover or non-crossover formation. Journal of Cell Science. 124: 501-13. PMID 21282472 DOI: 10.1242/jcs.074427 |
0.353 |
|
| 2011 |
Uringa EJ, Youds JL, Lisaingo K, Lansdorp PM, Boulton SJ. RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Research. 39: 1647-55. PMID 21097466 DOI: 10.1093/nar/gkq1045 |
0.46 |
|
| 2010 |
Adamo A, Collis SJ, Adelman CA, Silva N, Horejsi Z, Ward JD, Martinez-Perez E, Boulton SJ, La Volpe A. Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Molecular Cell. 39: 25-35. PMID 20598602 DOI: 10.1016/J.Molcel.2010.06.026 |
0.465 |
|
| 2010 |
Adelman CA, Boulton SJ. Metabolism of postsynaptic recombination intermediates. Febs Letters. 584: 3709-16. PMID 20493853 DOI: 10.1016/J.Febslet.2010.05.023 |
0.44 |
|
| 2010 |
Boulton SJ. DNA repair: Decision at the break point. Nature. 465: 301-2. PMID 20485424 DOI: 10.1038/465301a |
0.37 |
|
| 2010 |
Collis SJ, Boulton SJ. FANCM: fork pause, rewind and play. The Embo Journal. 29: 703-5. PMID 20160754 DOI: 10.1038/emboj.2009.415 |
0.402 |
|
| 2010 |
Ward JD, Muzzini DM, Petalcorin MI, Martinez-Perez E, Martin JS, Plevani P, Cassata G, Marini F, Boulton SJ. Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Molecular Cell. 37: 259-72. PMID 20122407 DOI: 10.1016/J.Molcel.2009.12.026 |
0.45 |
|
| 2009 |
Boulton SJ. DNA repair: A heavyweight joins the fray. Nature. 462: 857-8. PMID 20016586 DOI: 10.1038/462857a |
0.446 |
|
| 2009 |
Saito TT, Youds JL, Boulton SJ, Colaiácovo MP. Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates. Plos Genetics. 5: e1000735. PMID 19936019 DOI: 10.1371/journal.pgen.1000735 |
0.389 |
|
| 2009 |
Meier B, Barber LJ, Liu Y, Shtessel L, Boulton SJ, Gartner A, Ahmed S. The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans. The Embo Journal. 28: 3549-63. PMID 19779462 DOI: 10.1038/Emboj.2009.278 |
0.502 |
|
| 2009 |
Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science (New York, N.Y.). 325: 1240-3. PMID 19661379 DOI: 10.1126/Science.1177321 |
0.725 |
|
| 2009 |
Horejŝí Z, Collis SJ, Boulton SJ. FANCM-FAAP24 and HCLK2: roles in ATR signalling and the Fanconi anemia pathway. Cell Cycle (Georgetown, Tex.). 8: 1133-7. PMID 19282663 DOI: 10.4161/cc.8.8.8204 |
0.404 |
|
| 2009 |
Pauklin S, Burkert JS, Martin J, Osman F, Weller S, Boulton SJ, Whitby MC, Petersen-Mahrt SK. Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics. 182: 41-54. PMID 19237686 DOI: 10.1534/Genetics.109.101683 |
0.422 |
|
| 2009 |
Youds JL, Barber LJ, Boulton SJ. C. elegans: a model of Fanconi anemia and ICL repair. Mutation Research. 668: 103-16. PMID 19059419 DOI: 10.1016/j.mrfmmm.2008.11.007 |
0.459 |
|
| 2008 |
Collis SJ, Ciccia A, Deans AJ, Ho?ejší Z, Martin JS, Maslen SL, Skehel JM, Elledge SJ, West SC, Boulton SJ. FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex Molecular Cell. 32: 313-324. PMID 18995830 DOI: 10.1016/J.Molcel.2008.10.014 |
0.451 |
|
| 2008 |
London TB, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, Hickson ID, Boulton SJ, Hiom K. FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. The Journal of Biological Chemistry. 283: 36132-9. PMID 18978354 DOI: 10.1074/Jbc.M808152200 |
0.417 |
|
| 2008 |
Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell. 135: 261-71. PMID 18957201 DOI: 10.1016/J.Cell.2008.08.016 |
0.425 |
|
| 2008 |
Muzzini DM, Plevani P, Boulton SJ, Cassata G, Marini F. Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways. Dna Repair. 7: 941-50. PMID 18472307 DOI: 10.1016/J.Dnarep.2008.03.021 |
0.486 |
|
| 2008 |
Adamo A, Montemauri P, Silva N, Ward JD, Boulton SJ, La Volpe A. BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair. Embo Reports. 9: 287-92. PMID 18219312 DOI: 10.1038/sj.embor.7401167 |
0.449 |
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| 2008 |
Ahel I, Ahel D, Matsusaka T, Clark AJ, Pines J, Boulton SJ, West SC. Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature. 451: 81-5. PMID 18172500 DOI: 10.1038/Nature06420 |
0.739 |
|
| 2007 |
Murakawa Y, Sonoda E, Barber LJ, Zeng W, Yokomori K, Kimura H, Niimi A, Lehmann A, Zhao GY, Hochegger H, Boulton SJ, Takeda S. Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Research. 67: 8536-43. PMID 17875693 DOI: 10.1158/0008-5472.Can-07-1166 |
0.409 |
|
| 2007 |
Garcia-Muse T, Boulton SJ. Meiotic recombination in Caenorhabditis elegans. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 15: 607-21. PMID 17674149 DOI: 10.1007/s10577-007-1146-x |
0.356 |
|
| 2007 |
Ward JD, Barber LJ, Petalcorin MI, Yanowitz J, Boulton SJ. Replication blocking lesions present a unique substrate for homologous recombination. The Embo Journal. 26: 3384-96. PMID 17611606 DOI: 10.1038/sj.emboj.7601766 |
0.382 |
|
| 2007 |
Collis SJ, Boulton SJ. Emerging links between the biological clock and the DNA damage response. Chromosoma. 116: 331-9. PMID 17492458 DOI: 10.1007/s00412-007-0108-6 |
0.372 |
|
| 2007 |
Petalcorin MI, Galkin VE, Yu X, Egelman EH, Boulton SJ. Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proceedings of the National Academy of Sciences of the United States of America. 104: 8299-304. PMID 17483448 DOI: 10.1073/Pnas.0702805104 |
0.347 |
|
| 2007 |
Collis SJ, Barber LJ, Clark AJ, Martin JS, Ward JD, Boulton SJ. HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability. Nature Cell Biology. 9: 391-401. PMID 17384638 DOI: 10.1038/ncb1555 |
0.347 |
|
| 2007 |
Zhao GY, Sonoda E, Barber LJ, Oka H, Murakawa Y, Yamada K, Ikura T, Wang X, Kobayashi M, Yamamoto K, Boulton SJ, Takeda S. A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Molecular Cell. 25: 663-75. PMID 17349954 DOI: 10.1016/j.molcel.2007.01.029 |
0.407 |
|
| 2007 |
Boulton SJ. Cellular functions of the BRCA tumour-suppressor proteins. Biochemical Society Transactions. 34: 633-45. PMID 17052168 DOI: 10.1042/BST0340633 |
0.357 |
|
| 2006 |
Dengg M, Garcia-Muse T, Gill SG, Ashcroft N, Boulton SJ, Nilsen H. Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates. Embo Reports. 7: 1046-51. PMID 16964178 DOI: 10.1038/sj.embor.7400782 |
0.485 |
|
| 2006 |
Collis SJ, Barber LJ, Ward JD, Martin JS, Boulton SJ. C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair. Dna Repair. 5: 1398-406. PMID 16914393 DOI: 10.1016/j.dnarep.2006.06.010 |
0.474 |
|
| 2006 |
Boulton SJ. BRCA1-mediated ubiquitylation. Cell Cycle (Georgetown, Tex.). 5: 1481-6. PMID 16861894 DOI: 10.4161/cc.5.14.2930 |
0.381 |
|
| 2006 |
Petalcorin MI, Sandall J, Wigley DB, Boulton SJ. CeBRC-2 stimulates D-loop formation by RAD-51 and promotes DNA single-strand annealing. Journal of Molecular Biology. 361: 231-42. PMID 16843491 DOI: 10.1016/J.JMB.2006.06.020 |
0.453 |
|
| 2006 |
Polanowska J, Martin JS, Garcia-Muse T, Petalcorin MI, Boulton SJ. A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. The Embo Journal. 25: 2178-88. PMID 16628214 DOI: 10.1038/sj.emboj.7601102 |
0.462 |
|
| 2005 |
Garcia-Muse T, Boulton SJ. Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans. The Embo Journal. 24: 4345-55. PMID 16319925 DOI: 10.1038/sj.emboj.7600896 |
0.447 |
|
| 2005 |
Martin JS, Winkelmann N, Petalcorin MI, McIlwraith MJ, Boulton SJ. RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair. Molecular and Cellular Biology. 25: 3127-39. PMID 15798199 DOI: 10.1128/MCB.25.8.3127-3139.2005 |
0.508 |
|
| 2004 |
Boulton SJ, Martin JS, Polanowska J, Hill DE, Gartner A, Vidal M. BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans. Current Biology : Cb. 14: 33-9. PMID 14711411 DOI: 10.1016/J.Cub.2003.11.029 |
0.641 |
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| 2003 |
Huang RY, Boulton SJ, Vidal M, Almo SC, Bresnick AR, Chance MR. High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins. Biochemical and Biophysical Research Communications. 307: 928-34. PMID 12878200 DOI: 10.1016/S0006-291X(03)01265-8 |
0.518 |
|
| 2003 |
Reboul J, Vaglio P, Rual JF, Lamesch P, Martinez M, Armstrong CM, Li S, Jacotot L, Bertin N, Janky R, Moore T, Hudson JR, Hartley JL, Brasch MA, Vandenhaute J, ... Boulton S, et al. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nature Genetics. 34: 35-41. PMID 12679813 DOI: 10.1038/Ng1140 |
0.508 |
|
| 2002 |
Hofmann ER, Milstein S, Boulton SJ, Ye M, Hofmann JJ, Stergiou L, Gartner A, Vidal M, Hengartner MO. Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Current Biology : Cb. 12: 1908-18. PMID 12445383 DOI: 10.1016/S0960-9822(02)01262-9 |
0.654 |
|
| 2002 |
Chance MR, Bresnick AR, Burley SK, Jiang JS, Lima CD, Sali A, Almo SC, Bonanno JB, Buglino JA, Boulton S, Chen H, Eswar N, He G, Huang R, Ilyin V, et al. Structural genomics: a pipeline for providing structures for the biologist. Protein Science : a Publication of the Protein Society. 11: 723-38. PMID 11910018 DOI: 10.1110/Ps.4570102 |
0.489 |
|
| 2002 |
Boulton SJ, Gartner A, Reboul J, Vaglio P, Dyson N, Hill DE, Vidal M. Combined functional genomic maps of the C. elegans DNA damage response. Science (New York, N.Y.). 295: 127-31. PMID 11778048 DOI: 10.1126/Science.1065986 |
0.607 |
|
| 2002 |
Schumacher B, Hofmann K, Boulton S, Gartner A. The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Current Biology : Cb. 11: 1722-7. PMID 11696333 DOI: 10.1016/S0960-9822(01)00534-6 |
0.326 |
|
| 2001 |
Davy A, Bello P, Thierry-Mieg N, Vaglio P, Hitti J, Doucette-Stamm L, Thierry-Mieg D, Reboul J, Boulton S, Walhout AJ, Coux O, Vidal M. A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome. Embo Reports. 2: 821-8. PMID 11559592 DOI: 10.1093/Embo-Reports/Kve184 |
0.676 |
|
| 2001 |
Boulton SJ, Vincent S, Vidal M. Use of protein-interaction maps to formulate biological questions. Current Opinion in Chemical Biology. 5: 57-62. PMID 11166649 DOI: 10.1016/S1367-5931(00)00168-X |
0.506 |
|
| 2000 |
Walhout AJ, Boulton SJ, Vidal M. Yeast two-hybrid systems and protein interaction mapping projects for yeast and worm. Yeast (Chichester, England). 17: 88-94. PMID 10900455 DOI: 10.1002/1097-0061(20000630)17:2<88::Aid-Yea20>3.0.Co;2-Y |
0.671 |
|
| 1998 |
Boulton SJ, Jackson SP. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. The Embo Journal. 17: 1819-28. PMID 9501103 DOI: 10.1093/emboj/17.6.1819 |
0.643 |
|
| 1997 |
Boulton SJ, Jackson SP. Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Research. 24: 4639-48. PMID 8972848 DOI: 10.1093/NAR/24.23.4639 |
0.643 |
|
| 1996 |
Boulton SJ, Jackson SP. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. The Embo Journal. 15: 5093-5103. DOI: 10.1002/j.1460-2075.1996.tb00890.x |
0.61 |
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