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Sanjay Desai - Publications

Affiliations: 
Laboratory of malaria and vector research National Institutes of Health, Bethesda, MD 
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Desai SA. Unique Properties of Nutrient Channels on -Infected Erythrocytes. Pathogens (Basel, Switzerland). 12. PMID 37887727 DOI: 10.3390/pathogens12101211  0.459
2023 Sylla M, Gupta A, Shao J, Desai SA. Conditional permeabilization of the P. falciparum plasma membrane in infected cells links cation influx to reduced membrane integrity. Plos One. 18: e0283776. PMID 37014920 DOI: 10.1371/journal.pone.0283776  0.505
2022 Butler MM, Waidyarachchi SL, Shao J, Nguyen ST, Ding X, Cardinale SC, Morin LR, Kwasny SM, Ito M, Gezelle J, Jiminez-Di Az MB, Angulo-Barturen I, Jacobs RT, Burrows JN, Aron ZD, ... ... Desai SA, et al. Optimized pyridazinone nutrient channel inhibitors are potent and specific antimalarial leads. Molecular Pharmacology. PMID 35798366 DOI: 10.1124/molpharm.122.000549  0.514
2022 Desai SA. Epigenetics of malaria parasite nutrient uptake, but why? Trends in Parasitology. PMID 35641406 DOI: 10.1016/j.pt.2022.05.005  0.485
2022 Shao J, Arora G, Manzella-Lapeira J, Brzostowski JA, Desai SA. Kinetic Tracking of Plasmodium falciparum Antigens on Infected Erythrocytes with a Novel Reporter of Protein Insertion and Surface Exposure. Mbio. 13: e0040422. PMID 35420481 DOI: 10.1128/mbio.00404-22  0.41
2021 Macedo-Silva T, Desai SA, Wunderlich G. Improved Plasmodium falciparum dilution cloning through efficient quantification of parasite numbers and c-SNARF detection. Malaria Journal. 20: 279. PMID 34162381 DOI: 10.1186/s12936-021-03816-w  0.345
2021 Gezelle J, Saggu G, Desai SA. Promises and Pitfalls of Parasite Patch-clamp. Trends in Parasitology. PMID 33640269 DOI: 10.1016/j.pt.2021.02.002  0.41
2021 Schureck MA, Darling JE, Merk A, Shao J, Daggupati G, Srinivasan P, Olinares PDB, Rout MP, Chait BT, Wollenberg K, Subramaniam S, Desai SA. Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake. Elife. 10. PMID 33393463 DOI: 10.7554/eLife.65282  0.355
2020 Ahmad M, Manzella-Lapeira J, Saggu G, Ito D, Brzostowski JA, Desai SA. Live-Cell FRET Reveals that Malaria Nutrient Channel Proteins CLAG3 and RhopH2 Remain Associated throughout Their Tortuous Trafficking. Mbio. 11. PMID 32900800 DOI: 10.1128/mBio.01354-20  0.452
2020 Gupta A, Bokhari AAB, Pillai AD, Crater AK, Gezelle J, Saggu G, Nasamu AS, Ganesan SM, Niles JC, Desai SA. Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross. Plos Pathogens. 16: e1008363. PMID 32069335 DOI: 10.1371/journal.ppat.1008363  0.537
2018 Gupta A, Balabaskaran-Nina P, Nguitragool W, Saggu GS, Schureck MA, Desai SA. Erratum for Gupta et al., "CLAG3 Self-Associates in Malaria Parasites and Quantitatively Determines Nutrient Uptake Channels at the Host Membrane". Mbio. 9. PMID 31329791 DOI: 10.1128/Mbio.01181-18  0.647
2018 Gupta A, Balabaskaran-Nina P, Nguitragool W, Saggu GS, Schureck MA, Desai SA. CLAG3 Self-Associates in Malaria Parasites and Quantitatively Determines Nutrient Uptake Channels at the Host Membrane. Mbio. 9. PMID 29739907 DOI: 10.1128/Mbio.02293-17  0.714
2018 Kushwaha AK, Apolis L, Ito D, Desai SA. Increased Ca uptake by erythrocytes infected with malaria parasites: evidence for exported proteins and novel inhibitors. Cellular Microbiology. e12853. PMID 29726084 DOI: 10.1111/cmi.12853  0.411
2017 Ito D, Schureck MA, Desai SA. An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites. Elife. 6. PMID 28221136 DOI: 10.7554/eLife.23485  0.518
2016 Pain M, Fuller AW, Basore K, Pillai AD, Solomon T, Bokhari AA, Desai SA. Synergistic Malaria Parasite Killing by Two Types of Plasmodial Surface Anion Channel Inhibitors. Plos One. 11: e0149214. PMID 26866812 DOI: 10.1371/journal.pone.0149214  0.518
2015 Basore K, Cheng Y, Kushwaha AK, Nguyen ST, Desai SA. How do antimalarial drugs reach their intracellular targets? Frontiers in Pharmacology. 6: 91. PMID 25999857 DOI: 10.3389/fphar.2015.00091  0.392
2015 Sharma P, Rayavara K, Ito D, Basore K, Desai SA. A CLAG3 mutation in an amphipathic transmembrane domain alters malaria parasite nutrient channels and confers leupeptin resistance. Infection and Immunity. 83: 2566-74. PMID 25870226 DOI: 10.1128/IAI.02966-14  0.452
2015 Gupta A, Thiruvengadam G, Desai SA. The conserved clag multigene family of malaria parasites: essential roles in host-pathogen interaction. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 18: 47-54. PMID 25467627 DOI: 10.1016/j.drup.2014.10.004  0.456
2014 Bokhari AA, Mita-Mendoza NK, Fuller A, Pillai AD, Desai SA. High guanidinium permeability reveals dehydration-dependent ion selectivity in the plasmodial surface anion channel. Biomed Research International. 2014: 741024. PMID 25243175 DOI: 10.1155/2014/741024  0.48
2014 Zipprer EM, Neggers M, Kushwaha A, Rayavara K, Desai SA. A kinetic fluorescence assay reveals unusual features of Ca⁺⁺ uptake in Plasmodium falciparum-infected erythrocytes. Malaria Journal. 13: 184. PMID 24885754 DOI: 10.1186/1475-2875-13-184  0.317
2014 Nguitragool W, Rayavara K, Desai SA. Proteolysis at a specific extracellular residue implicates integral membrane CLAG3 in malaria parasite nutrient channels. Plos One. 9: e93759. PMID 24699906 DOI: 10.1371/Journal.Pone.0093759  0.706
2014 Desai SA. Why do malaria parasites increase host erythrocyte permeability? Trends in Parasitology. 30: 151-9. PMID 24507014 DOI: 10.1016/j.pt.2014.01.003  0.428
2013 Sharma P, Wollenberg K, Sellers M, Zainabadi K, Galinsky K, Moss E, Nguitragool W, Neafsey D, Desai SA. An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake. The Journal of Biological Chemistry. 288: 19429-40. PMID 23720749 DOI: 10.1074/Jbc.M113.468371  0.651
2013 Pillai AD, Addo R, Sharma P, Nguitragool W, Srinivasan P, Desai SA. Malaria parasites tolerate a broad range of ionic environments and do not require host cation remodelling. Molecular Microbiology. 88: 20-34. PMID 23347042 DOI: 10.1111/Mmi.12159  0.653
2012 Pillai AD, Nguitragool W, Lyko B, Dolinta K, Butler MM, Nguyen ST, Peet NP, Bowlin TL, Desai SA. Solute restriction reveals an essential role for clag3-associated channels in malaria parasite nutrient acquisition. Molecular Pharmacology. 82: 1104-14. PMID 22949525 DOI: 10.1124/Mol.112.081224  0.71
2012 Lyko B, Hammershaimb EA, Nguitragool W, Wellems TE, Desai SA. A high-throughput method to detect Plasmodium falciparum clones in limiting dilution microplates. Malaria Journal. 11: 124. PMID 22531353 DOI: 10.1186/1475-2875-11-124  0.617
2012 Desai SA. Ion and nutrient uptake by malaria parasite-infected erythrocytes. Cellular Microbiology. 14: 1003-9. PMID 22432505 DOI: 10.1111/j.1462-5822.2012.01790.x  0.36
2012 Alkhalil A, Hong L, Nguitragool W, Desai SA. Voltage-dependent inactivation of the plasmodial surface anion channel via a cleavable cytoplasmic component. Biochimica Et Biophysica Acta. 1818: 367-74. PMID 22115742 DOI: 10.1016/J.Bbamem.2011.11.010  0.666
2011 Nguitragool W, Bokhari AA, Pillai AD, Rayavara K, Sharma P, Turpin B, Aravind L, Desai SA. Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cells. Cell. 145: 665-77. PMID 21620134 DOI: 10.1016/J.Cell.2011.05.002  0.708
2010 Lisk G, Pain M, Sellers M, Gurnev PA, Pillai AD, Bezrukov SM, Desai SA. Altered plasmodial surface anion channel activity and in vitro resistance to permeating antimalarial compounds. Biochimica Et Biophysica Acta. 1798: 1679-88. PMID 20451492 DOI: 10.1016/j.bbamem.2010.04.013  0.312
2010 Pillai AD, Pain M, Solomon T, Bokhari AA, Desai SA. A cell-based high-throughput screen validates the plasmodial surface anion channel as an antimalarial target. Molecular Pharmacology. 77: 724-33. PMID 20101003 DOI: 10.1124/mol.109.062711  0.301
2010 Hill DA, Desai SA. Malaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool. Future Microbiology. 5: 81-97. PMID 20020831 DOI: 10.2217/fmb.09.109  0.319
2009 Rayavara K, Rajapandi T, Wollenberg K, Kabat J, Fischer ER, Desai SA. A complex of three related membrane proteins is conserved on malarial merozoites. Molecular and Biochemical Parasitology. 167: 135-43. PMID 19465059 DOI: 10.1016/j.molbiopara.2009.05.006  0.308
2009 Alkhalil A, Pillai AD, Bokhari AA, Vaidya AB, Desai SA. Complex inheritance of the plasmodial surface anion channel in a Plasmodium falciparum genetic cross. Molecular Microbiology. 72: 459-69. PMID 19320831 DOI: 10.1111/J.1365-2958.2009.06661.X  0.525
2008 Bokhari AA, Solomon T, Desai SA. Two distinct mechanisms of transport through the plasmodial surface anion channel. The Journal of Membrane Biology. 226: 27-34. PMID 19050955 DOI: 10.1007/s00232-008-9136-2  0.342
2008 Lisk G, Pain M, Gluzman IY, Kambhampati S, Furuya T, Su XZ, Fay MP, Goldberg DE, Desai SA. Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes. Antimicrobial Agents and Chemotherapy. 52: 2346-54. PMID 18443109 DOI: 10.1128/Aac.00057-08  0.476
2007 Staines HM, Alkhalil A, Allen RJ, De Jonge HR, Derbyshire E, Egée S, Ginsburg H, Hill DA, Huber SM, Kirk K, Lang F, Lisk G, Oteng E, Pillai AD, Rayavara K, ... ... Desai SA, et al. Electrophysiological studies of malaria parasite-infected erythrocytes: current status. International Journal For Parasitology. 37: 475-82. PMID 17292372 DOI: 10.1016/J.Ijpara.2006.12.013  0.42
2007 Lisk G, Scott S, Solomon T, Pillai AD, Desai SA. Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process. Molecular Pharmacology. 71: 1241-50. PMID 17287402 DOI: 10.1124/mol.106.030734  0.314
2007 Hill DA, Pillai AD, Nawaz F, Hayton K, Doan L, Lisk G, Desai SA. A blasticidin S-resistant Plasmodium falciparum mutant with a defective plasmodial surface anion channel. Proceedings of the National Academy of Sciences of the United States of America. 104: 1063-8. PMID 17213308 DOI: 10.1073/Pnas.0610353104  0.536
2007 Alkhalil A, Hill DA, Desai SA. Babesia and plasmodia increase host erythrocyte permeability through distinct mechanisms. Cellular Microbiology. 9: 851-60. PMID 17087736 DOI: 10.1111/j.1462-5822.2006.00834.x  0.337
2006 Lisk G, Kang M, Cohn JV, Desai SA. Specific inhibition of the plasmodial surface anion channel by dantrolene. Eukaryotic Cell. 5: 1882-93. PMID 16950925 DOI: 10.1128/EC.00212-06  0.356
2005 Desai SA. Open and closed states of the plasmodial surface anion channel. Nanomedicine : Nanotechnology, Biology, and Medicine. 1: 58-66. PMID 17292059 DOI: 10.1016/j.nano.2004.11.001  0.3
2005 Lisk G, Desai SA. The plasmodial surface anion channel is functionally conserved in divergent malaria parasites. Eukaryotic Cell. 4: 2153-9. PMID 16339732 DOI: 10.1128/EC.4.12.2153-2159.2005  0.506
2005 Kang M, Lisk G, Hollingworth S, Baylor SM, Desai SA. Malaria parasites are rapidly killed by dantrolene derivatives specific for the plasmodial surface anion channel. Molecular Pharmacology. 68: 34-40. PMID 15843600 DOI: 10.1124/mol.104.010553  0.512
2005 Desai SA, Alkhalil A, Kang M, Ashfaq U, Nguyen ML. Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum. The Journal of Biological Chemistry. 280: 16861-7. PMID 15701633 DOI: 10.1074/jbc.M414629200  0.484
2004 Alkhalil A, Cohn JV, Wagner MA, Cabrera JS, Rajapandi T, Desai SA. Plasmodium falciparum likely encodes the principal anion channel on infected human erythrocytes. Blood. 104: 4279-86. PMID 15319279 DOI: 10.1182/blood-2004-05-2047  0.411
2004 Desai SA. Targeting ion channels of Plasmodium falciparum-infected human erythrocytes for antimalarial development. Current Drug Targets. Infectious Disorders. 4: 79-86. PMID 15032636  0.384
2003 Cohn JV, Alkhalil A, Wagner MA, Rajapandi T, Desai SA. Extracellular lysines on the plasmodial surface anion channel involved in Na+ exclusion. Molecular and Biochemical Parasitology. 132: 27-34. PMID 14563534  0.351
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