R. Jeffrey Neitz
Affiliations: | 2003 | University of Michigan, Ann Arbor, Ann Arbor, MI |
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"R. Neitz"Parents
Sign in to add mentor| William R. Roush | grad student | 2003 | University of Michigan | |
| (Total synthesis of the structure of the putative landomycin aglycone, revision of the structure and studies directed toward the synthesis of the proposed structure of the landomycin aglycone.) | ||||
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| Konstantinidou M, Visser EJ, Vandenboorn E, et al. (2023) Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3σ/ERα Protein-Protein Interaction from Nonselective Fragments. Journal of the American Chemical Society |
| Gahbauer S, Correy GJ, Schuller M, et al. (2023) Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America. 120: e2212931120 |
| Gahbauer S, Correy GJ, Schuller M, et al. (2022) Structure-based inhibitor optimization for the Nsp3 Macrodomain of SARS-CoV-2. Biorxiv : the Preprint Server For Biology |
| LaPorte MG, Burnett JC, Colombo R, et al. (2018) Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97. Acs Medicinal Chemistry Letters. 9: 1075-1081 |
| Alverez C, Bulfer SL, Chakrasali R, et al. (2016) Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. Acs Medicinal Chemistry Letters. 7: 182-7 |
| Banerjee S, Bartesaghi A, Merk A, et al. (2016) 2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition. Science (New York, N.Y.) |
| Long T, Neitz RJ, Beasley R, et al. (2016) Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni. Plos Neglected Tropical Diseases. 10: e0004356 |
| Alverez C, Bulfer SL, Chakrasali R, et al. (2016) Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway Acs Medicinal Chemistry Letters. 7: 182-187 |
| Alverez C, Arkin MR, Bulfer SL, et al. (2015) Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97. Acs Medicinal Chemistry Letters. 6: 1225-30 |
| Neitz RJ, Bryant C, Chen S, et al. (2015) Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease. Bioorganic & Medicinal Chemistry Letters. 25: 4834-7 |