William R. Roush
Affiliations: | 1978-1987 | Massachusetts Institute of Technology, Cambridge, MA, United States | |
1987-1997 | Indiana University, Bloomington, Bloomington, IN, United States | ||
1997-2004 | University of Michigan, Ann Arbor, Ann Arbor, MI | ||
2004- | Chemistry | Scripps Research Institute Florida |
Area:
Medicinal ChemistryWebsite:
http://www.scripps.edu/roush/Roush.htmlGoogle:
"William R. Roush"Bio:
http://um2017.org/faculty-history/faculty/william-r-roush
Cross-listing: MichiganTree
Parents
Sign in to add mentorJulius Rebek, Jr. | research assistant | 1974 | UCLA |
Robert B. Woodward | grad student | 1977 | Harvard |
Children
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Publications
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Choi JY, Noguchi Y, Alburger JM, et al. (2023) Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ. Journal of Medicinal Chemistry |
Shahoei R, Pangeni S, Sanders MA, et al. (2022) Molecular Modeling of ABHD5 Structure and Ligand Recognition. Frontiers in Molecular Biosciences. 9: 935375 |
Jílková A, Rubešová P, Fanfrlík J, et al. (2020) Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors. Acs Infectious Diseases |
Doebelin C, He Y, Campbell S, et al. (2019) Discovery and optimization of a series of sulfonamide inverse agonists for the retinoic acid receptor-related receptor-α. Medicinal Chemistry (Shariqah (United Arab Emirates)) |
Mahmud I, Tian G, Wang J, et al. (2019) Abstract 4718: SR-4370, a potent and selective inhibitor of class I HDACs, suppresses AR signaling and in vivo prostate tumor growth Cancer Research |
Zyserman I, Mondal D, Sarabia F, et al. (2018) Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri. Experimental Parasitology |
Tian G, Mahmud I, Stowe R, et al. (2018) Abstract B004: A combination of two chemically distinct inhibitors of class I HDACs is highly effective to suppress AR signaling and in vivo growth of prostate cancer xenograft Cancer Research. 78 |
Mahmud I, Garrett TJ, Stowe R, et al. (2018) Abstract LB-248: Chemically distinct class I HDAC inhibitors synergize to inhibit global lipid metabolism in cancer Cancer Research. 78 |
Monastyrskyi A, Nilchan N, Quereda V, et al. (2017) Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer. Bioorganic & Medicinal Chemistry |
Rondini EA, Mladenovic-Lucas L, Roush WR, et al. (2017) Novel pharmacological probes reveal ABHD5 as a locus of lipolysis control in white and brown adipocytes. The Journal of Pharmacology and Experimental Therapeutics |