Douglas R. Davies, Ph.D.
Affiliations: | 2000 | University of Wisconsin, Madison, Madison, WI |
Area:
Structural BiologyGoogle:
"Douglas Davies"Parents
Sign in to add mentor| Ivan Rayment | grad student | 2000 | UW Madison | |
| (Structural studies of Tn5 transposase.) | ||||
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Publications
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| Rai G, Urban DJ, Mott BT, et al. (2020) Pyrazole-Based Lactate Dehydrogenase (LDH) Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. Journal of Medicinal Chemistry |
| Dumais M, Davies DR, Lin T, et al. (2018) Structure and analysis of nucleoside diphosphate kinase from Borrelia burgdorferi prepared in a transition-state complex with ADP and vanadate moieties. Acta Crystallographica. Section F, Structural Biology Communications. 74: 373-384 |
| Rai G, Brimacombe KR, Mott BT, et al. (2017) Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). Journal of Medicinal Chemistry |
| Ojo KK, Ranade RM, Zhang Z, et al. (2016) Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One. 11: e0160350 |
| Gelinas AD, Davies DR, Janjic N. (2016) Embracing proteins: structural themes in aptamer-protein complexes. Current Opinion in Structural Biology. 36: 122-132 |
| Jarvis TC, Davies DR, Hisaminato A, et al. (2015) Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure (London, England : 1993). 23: 1293-304 |
| Phan IQ, Davies DR, Moretti NS, et al. (2015) Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. Acta Crystallographica. Section F, Structural Biology Communications. 71: 615-21 |
| Gelinas AD, Davies DR, Edwards TE, et al. (2014) Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. The Journal of Biological Chemistry. 289: 8720-34 |
| Davies DR, Gelinas AD, Zhang C, et al. (2012) Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proceedings of the National Academy of Sciences of the United States of America. 109: 19971-6 |
| Begley DW, Davies DR, Hartley RC, et al. (2011) Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1060-9 |