Christian B. Anfinsen

Affiliations:

Johns Hopkins University School of Medicine, Baltimore, MD, United States

Area:

Protein chemistry

Website:

http://nobelprize.org/nobel_prizes/chemistry/laureates/1972/anfinsen-bio.html

Google:

"Christian Boemer Anfinsen"

Bio:

(1916 - 1995)
The Nobel Prize in Chemistry 1972 was divided, one half awarded to Christian B. Anfinsen "for his work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation", the other half jointly to Stanford Moore and William H. Stein "for their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule".
http://www.nasonline.org/member-directory/deceased-members/58204.html
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Parents

A. Baird Hastings	grad student	1943	Harvard Medical School
(Quantitative Histochemical Studies of the Retina)
Kaj Linderstrøm-Lang	research scientist	1954-1955	Carlsberg Laboratory

Children

M. Christina White	research assistant	1992-1993	Johns Hopkins
Daniel Steinberg	grad student	1952	Harvard
Charles J. Epstein	post-doc		NIH (Neurotree)
Thressa Campbell Stadtman	post-doc	1950	Harvard Medical School
Michael Sela	post-doc	1956-1957	NIH
Robert S. Adelstein	post-doc	1961	NIH
Edgar Haber	post-doc	1959-1962	NIH
Pedro Cuatrecasas	post-doc	1966-1967	NIH
Irwin M. Chaiken	post-doc	1969-1970	NIH
Theodore Adolphus Bremner	post-doc	1974	NIH (GenetiTree)
Ben M. Dunn	post-doc	1971-1974	NIH (Microtree)
Bruce Furie	post-doc	1972-1974	NIH (NIAMDD)
John A. Gerlt	post-doc	1974-1975	NIH
Martha Vaughan	research scientist		NIH
Edward David Korn	research scientist	1954	NIH
Robert F. Goldberger	research scientist	1961-1964	National Institutes of Health, Bethesda (Microtree)

Collaborators

BETA: Related publications

Publications

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Furie B, Schechter AN, Sachs DH, et al. (1975) An immunological approach to the conformational equilibrium of staphylococcal nuclease. Journal of Molecular Biology. 92: 497-506
Dunn BM, Anfinsen CB. (1974) Kinetics of Woodward's Reagent K hydrolysis and reaction with staphylococcal nuclease. The Journal of Biological Chemistry. 249: 3717-23
Furie B, Schechter AN, Sachs DH, et al. (1974) Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease. Biochemistry. 13: 1561-6
Sachs DH, Schecter AN, Eastlake A, et al. (1974) Immunological distinction between the possible origins of enzymatic activity in a polypeptide fragment of staphylococcal nuclease. Nature. 251: 242-4
Eastlake A, Sachs DH, Schechter AN, et al. (1974) Binding of univalent antibody fragments to a distinct antigenic determinant of staphylococcal nuclease. Biochemistry. 13: 1567-71
Furie B, Eastlake A, Schechter AN, et al. (1973) The interaction of the lanthanide ions with staphylococcal nuclease. The Journal of Biological Chemistry. 248: 2821-5
Fuchs S, Sela M, Anfinsen CB. (1973) Nuclease-coated bacteriophage: a sensitive tool for studying antigenic reactivity of synthetic sequence fragments. Archives of Biochemistry and Biophysics. 154: 601-5
Dunn BM, DiBello C, Anfinsen CB. (1973) The pH dependence of the steady state kinetic parameters for staphylococcal nuclease-catalyzed hydrolysis of deoxythymidine-3'-phosphate-5'-p-nitrophenylphosphate in H 2 O and D 2 O. The Journal of Biological Chemistry. 248: 4769-74
Sánchez GR, Chaiken IM, Anfinsen CB. (1973) Structure-function relationships at the active site of nuclease-T'. The Journal of Biological Chemistry. 248: 3653-9
Anfinsen C, Goldberger R, Schechter A. (1973) Current topics in Biochemistry. National institutes of health lectures in biomedical sciences Food and Cosmetics Toxicology. 11: 1116-1117