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Ethan A. Englund, Ph.D.

Affiliations: 
2007 Chemistry Northwestern University, Evanston, IL 
Area:
Organic Chemistry
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Daniel H. Appella grad student 2007 Northwestern
 (Chemically-modified peptide nucleic acids: A versatile approach to complex molecular scaffolding and control of nucleic acid secondary architecture.)
Daniel H. Appella post-doc National Insitutes of Health

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Publications

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Shank N, George Rosenker KM, Englund EA, et al. (2019) Synthesis and Application of KγT Peptide Nucleic Acids. Methods in Molecular Biology (Clifton, N.J.). 1973: 131-145
Gaynutdinov TI, Englund EA, Appella DH, et al. (2015) G-quadruplex formation between G-rich PNA and homologous sequences in oligonucleotides and supercoiled plasmid DNA. Nucleic Acid Therapeutics. 25: 78-84
Englund EA, Gupta P, Micklitsch CM, et al. (2014) PPG peptide nucleic acids that promote DNA guanine quadruplexes. Chembiochem : a European Journal of Chemical Biology. 15: 1887-90
Englund EA, Zhang N, Appella DH. (2014) Cyclopentane peptide nucleic acids. Methods in Molecular Biology (Clifton, N.J.). 1050: 13-8
Panyutin IG, Onyshchenko MI, Englund EA, et al. (2012) Targeting DNA G-quadruplex structures with peptide nucleic acids. Current Pharmaceutical Design. 18: 1984-91
Englund EA, Wang D, Fujigaki H, et al. (2012) Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds. Nature Communications. 3: 614
Onyshchenko MI, Gaynutdinov TI, Englund EA, et al. (2011) Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region. Nucleic Acids Research. 39: 7114-23
Onyshchenko MI, Gaynutdinov TI, Englund EA, et al. (2009) Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs. Nucleic Acids Research. 37: 7570-80
Englund EA, Appella DH. (2007) Gamma-substituted peptide nucleic acids constructed from L-lysine are a versatile scaffold for multifunctional display. Angewandte Chemie (International Ed. in English). 46: 1414-8
Englund EA, Xu Q, Witschi MA, et al. (2006) PNA-DNA duplexes, triplexes, and quadruplexes are stabilized with trans-cyclopentane units. Journal of the American Chemical Society. 128: 16456-7
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