Jonathan B. Cohen, Ph.D.
Affiliations: | Massachusetts General Hospital, Boston, MA | ||
| 1975-1982 | Pharmacology | Harvard Medical School, Boston, MA, United States | |
| 1982-1992 | Anatomy and Neurobiology | Washington University School of Medicine, St. Louis, MO, United States | |
| 1992- | Neurobiology | Harvard Medical School, Boston, MA, United States |
Area:
nicotinic acetylcholine receptors (AChR) and GABAa receptorsWebsite:
http://www.fas.harvard.edu/~biophys/Jonathan_B_Cohen.htmGoogle:
"Jonathan B. Cohen"Bio:
http://www.hms.harvard.edu/dms/neuroscience/fac/cohen.php
http://www.hms.harvard.edu/bss/neuro/cohen/
http://neuro.med.harvard.edu/faculty/cohen.html
Cross-listing: Neurotree
Parents
Sign in to add mentor| Edgar Bright Wilson | grad student | 1972 | Harvard | |
| (Microwave-microwave double resonance investigations of collisional transfer of rotational energy) | ||||
| Jean-Pierre Changeux | post-doc | Institut Pasteur | ||
Children
Sign in to add trainee| Richard Neubig | grad student | 1980 | Harvard Medical School (Neurotree) |
| Marcus L. Ware | grad student | 2000 | Harvard (Neurotree) |
| Jonathan C. Trinidad | grad student | 2003 | Harvard (Neurotree) |
| Michael J. Bianchetta | grad student | 2004 | Harvard (Neurotree) |
| Filbert H. Hong | grad student | 2004 | Harvard (Neurotree) |
| Laura M. Magnotti | grad student | 2010 | Harvard (Neurotree) |
| Steen E. Pedersen | post-doc | 1984-1989 | Washington University |
| Marc Bartoli | post-doc | 1999-2001 | Harvard Medical School (Neurotree) |
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Publications
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| McGrath M, Hoyt H, Pence A, et al. (2020) Competitive Antagonism of Etomidate Action by Diazepam. Anesthesiology. 133: 583-594 |
| McGrath M, Hoyt H, Pence A, et al. (2020) Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology |
| Jayakar SS, Chiara DC, Zhou X, et al. (2020) Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry |
| Shalabi AR, Yu Z, Zhou X, et al. (2020) A potent photoreactive general anesthetic with novel binding site selectivity for GABA receptors. European Journal of Medicinal Chemistry. 194: 112261 |
| Yu Z, Chiara DC, Savechenkov PY, et al. (2019) A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor. The Journal of Biological Chemistry |
| Yu Z, Savechenkov PY, Bruzik KS, et al. (2019) Identifying Steroid Binding Sites in a Nicotinic Acetylcholine Receptor (nAChR) with a Photoreactive Analog of Alphaxalone Biophysical Journal. 116: 395a |
| Chiara DC, Wu B, Zhou X, et al. (2019) Identification of a High-Affinity Neurosteroid Binding Site in Human Alpha1Beta3 GabaAR using a Photoreactive Thdoc Analog Biophysical Journal. 116: 392a |
| Jayakar SS, Zhou X, Wu B, et al. (2019) Pharmacological Selectivity of a Steroid Binding Site at the Beta+-Alpha− Interface of Alpha1 Beta3 Gaba-A Receptors Biophysical Journal. 116: 392a |
| Wu B, Jayakar SS, Zhou X, et al. (2018) Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824 |
| McGrath M, Yu Z, Jayakar SS, et al. (2018) Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology |