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Chuan He

Affiliations: 
2002- Chemistry University of Chicago, Chicago, IL 
Website:
http://chemistry.uchicago.edu/faculty/faculty/person/member/chuan-he.html
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"Chuan He"
Bio:

Shared the Wolf Prize in Chemistry 2023 "for discovering reversible RNA methylation and its role in the regulation of gene expression."

Parents

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Stephen James Lippard grad student 2000 MIT
 (Synthesis and reactivity of cobalt, zinc, copper and iron dimetallic complexes using Bis(carboxylate) and 1,8-napthyridine-based dinucleating ligands)
Gregory L. Verdine post-doc 2000-2002 Harvard

Children

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Chengqi Yi grad student Chicago
Yukiko Mishina grad student 2006 Chicago
Peng R. Chen grad student 2002-2007 Chicago
Erica M. Duguid grad student 2008 Chicago
Zigang Li grad student 2009 Chicago
Uddhav K. Shigdel grad student 2009 Chicago
Chad Brouwer grad student 2010 Chicago
Xing Jian grad student 2010 Chicago
Seraphine V. Wegner grad student 2010 Chicago
David A. Capretto grad student 2011 Chicago
Catherine B. Poor grad student 2011 Chicago
Pedro Brugarolas Brufau grad student 2012 Chicago
Kyle T. Dolan grad student 2012 Chicago
Ye Fu grad student 2012 Chicago
Fei Sun grad student 2012 Chicago
Elizabeth A. Wiltrout grad student 2012 Chicago
Stephanie H. Kim grad student 2013 Chicago
Chunxiao Song grad student 2013 Chicago
Guanqun Zheng grad student 2013 Chicago
Michael Bosscher grad student 2014 Chicago
Quanjiang Ji grad student 2014 Chicago
Xiao Wang grad student 2010-2015 University of Chicago & HHMI
Boxuan Simen Zhao grad student 2012-2017 Chicago
Jiangbo Wei grad student 2015-2021 Chicago
Xinran Feng grad student 2020-2023 Chicago (Neurotree)
Kathy Fange Liu post-doc Chicago
Junliang Zhang post-doc
Matthew O. Ross post-doc 2019- Chicago
Jiangbo Wei post-doc 2021- Chicago
Zhangjie Shi post-doc 2003-2004 Chicago
Huiqing Zhou post-doc 2017-2020 Chicago
BETA: Related publications

Publications

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Xiao L, De Jesus DF, Ju CW, et al. (2025) Divergent roles of mA in orchestrating brown and white adipocyte transcriptomes and systemic metabolism. Nature Communications. 16: 533
Xiang B, Zhang M, Li K, et al. (2025) The epitranscriptional factor PCIF1 orchestrates CD8 T cell ferroptosis and activation to control antitumor immunity. Nature Immunology
Cui YH, Wei J, Fan H, et al. (2024) Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 121: e2407910121
Kahraman S, De Jesus DF, Wei J, et al. (2024) mA mRNA methylation by METTL14 regulates early pancreatic cell differentiation. The Embo Journal
Shi Z, Wen K, Zou Z, et al. (2024) YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges. Biorxiv : the Preprint Server For Biology
Ross MO, Xie Y, Owyang RC, et al. (2024) PTPN2 copper-sensing relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression. Nature Communications. 15: 6947
Cui XL, Nie J, Zhu H, et al. (2024) LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA. Genome Biology. 25: 157
Wang G, Li H, Ye C, et al. (2024) Quantitative profiling of mA at single base resolution across the life cycle of rice and Arabidopsis. Nature Communications. 15: 4881
Zahid OK, Zhao BS, He C, et al. (2024) Author Correction: Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores. Scientific Reports. 14: 7881
F De Jesus D, Zhang Z, Brown NK, et al. (2024) Redox regulation of mA methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes. Nature Cell Biology
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