Kathy Fange Liu, Ph.D.
Affiliations: | 2008-2013 | Department of Chemistry | Georgia State University, Atlanta, GA, United States |
| 2013-2017 | Department of Chemistry | University of Chicago, Chicago, IL | |
| 2018- | Department of Biochemistry and Biophysics | University of Pennsylvania, Philadelphia, PA, United States |
Area:
RNA enzymology, Sex-specific RNA biology, Protein structure-functionWebsite:
https://www.med.upenn.edu/kathyliulab/Google:
"Fange Liu"Children
Sign in to add trainee| Justin Curtiss | grad student | Penn | |
| Heidi Elashal | grad student | Penn | |
| Ellen Lavorando | grad student | Penn | |
| Michael Owens | grad student | Penn | |
| Amber Yanas | grad student | Penn | |
| Robert Jordan Ontiveros | grad student | 2018-2022 | Penn |
| Julian Stoute | grad student | 2018-2023 | Penn |
| Yulia Gonskikh | post-doc | Penn | |
| Yulia Gonskikh | post-doc | Penn | |
| Maria Sarai Mendoza | post-doc | Penn | |
| Hui Shen | post-doc | Penn | |
| Xiaoyu Wei | research scientist | 2022- | Penn |
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Publications
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| Wei X, Sampson N, Figueroa Mendoza SM, et al. (2025) Fault-Tolerance Study on a Positive-Charged Cleft in 18 rRNA Methyltransferase DIMT1. Biochemistry |
| Gonskikh Y, Tirrito C, Bommisetti P, et al. (2024) Spatial regulation of NSUN2-mediated tRNA m5C installation in cognitive function. Nucleic Acids Research |
| Yanas A, Shweta H, Owens MC, et al. (2024) RNA helicases DDX3X and DDX3Y form nanometer-scale RNA-protein clusters that support catalytic activity. Current Biology : Cb |
| Owens MC, Shen H, Yanas A, et al. (2024) Specific catalytically impaired DDX3X mutants form sexually dimorphic hollow condensates. Nature Communications. 15: 9553 |
| Owens MC, Yanas A, Liu KF. (2024) Sex chromosome-encoded protein homologs: current progress and open questions. Nature Structural & Molecular Biology. 31: 1156-1166 |
| Lavorando E, Owens MC, Liu KF. (2024) Comparing the roles of sex chromosome-encoded protein homologs in gene regulation. Genes & Development |
| Yanas A, Shweta H, Owens MC, et al. (2023) DDX3X and DDX3Y constitutively form nano-sized RNA-protein clusters that foster enzymatic activity. Biorxiv : the Preprint Server For Biology |
| Owens MC, Shen H, Yanas A, et al. (2023) Mutant forms of DDX3X with diminished catalysis form hollow condensates that exhibit sex-specific regulation. Biorxiv : the Preprint Server For Biology |
| Maldonado López AM, Ko EK, Huang S, et al. (2023) Mettl3-catalyzed mA regulates histone modifier and modification expression in self-renewing somatic tissue. Science Advances. 9: eadg5234 |
| Chen AY, Owens MC, Liu KF. (2023) Coordination of RNA modifications in the brain and beyond. Molecular Psychiatry |