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David A. Colby

Affiliations: 
Chemistry Purdue University, West Lafayette, IN, United States 
Area:
natural product synthesis
Website:
http://www.chem.purdue.edu/people/faculty/faculty.asp?itemID=86
Google:
"David A. Colby"
Bio:

http://people.pharmacy.purdue.edu/~dcolby/david.html

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Parents

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A. Richard Chamberlin grad student 2006 UC Irvine
 (Refining the pharmacophore for phosphatase inhibition and structure-based design of okadaic acid analogs)
Dale L. Boger post-doc 2006-2008 Scripps Institute

Children

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Munia Sowaileh grad student 2013- University of Missisippi School of Pharmacy
Francis J. Barrios grad student 2013 Purdue
Changho Han grad student 2013 Purdue
Mark V. Riofski grad student 2013 Purdue
Baharul Islam grad student 2019-2023 University of Mississippi
Eun Hoo [Uno] Hoo Kim post-doc Purdue
Hari R. Khatri post-doc 2016- University of Missisippi School of Pharmacy
Alex L. Nguyen post-doc 2016- The University of Mississippi

Collaborators

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Publications

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Islam B, Kreusel KE, Sulochana SP, et al. (2024) Stability studies of β-Amino- and β-Hydroxy difluoromethyl ketones in rat serum and rat liver microsomes. Bioorganic & Medicinal Chemistry Letters. 113: 129964
Islam B, Colby DA. (2023) Transient Formation of Hemiketals from Pentafluoro--diols in the Presence of Alcohols. Journal of Fluorine Chemistry. 270
Khatri HR, Han C, Alkhodier RA, et al. (2022) Generation of formaldehyde and formaldehyde-d for hydroxymethylations and hydroxydeuteromethylations of difluoroenolates and difluorobenzyl carbanions. Chemical Communications (Cambridge, England). 58: 5490-5493
Sowaileh MF, Alshammari MD, Colby DA. (2021) Synthesis of Difluorinated Halohydrins by the Chemoselective Addition of Difluoroenolates to α-Haloketones. Organic Letters
Adam AT, Fronczek FR, Colby DA. (2020) Synthesis of β-Fluoro-α,β-Unsaturated Amides from the Fragmentation of Morpholine 3,3,3-Trifluoropropanamide by Grignard Reagents. Organic Letters
Khatri HR, Han C, Luong E, et al. (2019) Controlling the Cleavage of Carbon-Carbon Bonds to Generate α,α-Difluorobenzyl Carbanions for the Construction of Difluoromethylbenzenes. The Journal of Organic Chemistry
Sowaileh MF, Salyer AE, Roy KK, et al. (2018) Agonists of the γ-aminobutyric acid type B (GABA) receptor derived from β-hydroxy and β-amino difluoromethyl ketones. Bioorganic & Medicinal Chemistry Letters
Nguyen AL, Khatri HR, Woods JR, et al. (2018) Magnesium-promoted Additions of Difluoroenolates to Unactivated Imines. The Journal of Organic Chemistry
Sowaileh MF, Han C, Hazlitt RA, et al. (2017) Conversion of Methyl Ketones and Methyl Sulfones into α-Deutero-α,α-Difluoromethyl Ketones and α-Deutero-α,α-Difluoromethyl Sulfones in Three Synthetic Steps. Tetrahedron Letters. 58: 396-400
Sowaileh MF, Hazlitt RA, Colby DA. (2017) Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement. Chemmedchem
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