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John C. Vederas, Ph.D.

Affiliations: 
1977- Chemistry University of Alberta, Edmonton, Alberta, Canada 
Area:
Bioorganic chemistry
Website:
http://www.chem.ualberta.ca/~vederas/home.html
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"John Vederas"
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Parents

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George H. Büchi grad student 1973 MIT
Christoph Tamm post-doc 1973-1976 University of Basel
Heinz G. Floss post-doc 1976-1977 Purdue

Children

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Paul Hedley Harrison grad student 1983-1987 The University of Alberta, Canada
Karine Auclair grad student 1999 University of Alberta
Jiasheng Fu grad student 2000 University of Alberta
Manjinder S. Lall grad student 2000 University of Alberta
Liang Z. Yan grad student 2000 University of Alberta
Jennifer F. Caplan grad student 2001 University of Alberta
Yeeman K. Ramtohul grad student 2002 University of Alberta
Michael M. Pollard grad student 2003 York University
John L. Sorensen grad student 2003 University of Alberta
Sylvie Garneau-Tsodikova grad student 1998-2003 University of Alberta
Karen Kawulka grad student 2004 University of Alberta
Nathaniel I. Martin grad student 2004 University of Alberta
Jake Stymiest grad student 2004 University of Alberta
Douglas Burr grad student 2006 University of Alberta
Andrew Scholte grad student 2006 University of Alberta
Lara Silkin grad student 2006 University of Alberta
Dan Spantulescu grad student 2006 University of Alberta
Marc Boudreau grad student 2007 University of Alberta
Jamie B. Cote grad student 2007 University of Alberta
Darren Derksen grad student 2007 University of Alberta
Mitch Flegel grad student 2007 University of Alberta
Vijay Pattabiraman grad student 2007 University of Alberta
Hongqiang (Patrick) Liu grad student 2010 University of Alberta
Leah Martin-Visscher grad student 2010 University of Alberta
Sabesan (Jay) Yoganathan grad student 2010 University of Alberta
Clarissa S. Sit grad student 2011 University of Alberta
Chenguang Fan grad student 2012 University of Alberta
Zedu Huang grad student 2012 University of Alberta
Avena C. Ross grad student 2012 University of Alberta
Zhizeng Gao grad student 2013 University of Alberta
Keyur Pandya grad student 2013 University of Alberta
Christopher Lohans grad student 2014 University of Alberta
Rachel Cochrane grad student 2010-2015 University of Alberta
Stephen Cochrane grad student 2010-2015 University of Alberta
Yeong-Chan Ahn grad student 2013-2018 University of Alberta
Albert Remus Romero Rosana grad student 2017-2020 University of Alberta (Evolution Tree)
Isaac Antwi grad student 2016-2021 University of Alberta
Hanna Pettersson post-doc 2004 University of Alberta
Christopher Diaper post-doc 2005 University of Alberta
Lucas Gursky post-doc 2006 University of Alberta
Matthew D. Clay post-doc 2006-2008 University of Alberta
Viji Moorthie post-doc 2006-2008 University of Alberta
Jennifer Chaytor post-doc 2012 University of Alberta
David Dietrich post-doc 2013 University of Alberta
Brandon Findlay post-doc 2013-2015 University of Alberta

Collaborators

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Brian D. Ames collaborator 2008-2012 University of Alberta (Microtree)
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Publications

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Van Oers TJ, Piercey A, Belovodskiy A, et al. (2023) Deuteration for Metabolic Stabilization of SARS-CoV-2 Inhibitors GC373 and Nirmatrelvir. Organic Letters. 25: 5885-5889
Lamer T, van Belkum MJ, Wijewardane A, et al. (2022) SPI "sandwich": Combined SUMO-Peptide-Intein expression system and isolation procedure for improved stability and yield of peptides. Protein Science : a Publication of the Protein Society. 31: e4316
Antwi I, Chiorean S, van Belkum MJ, et al. (2020) Unveiling the active isomer of cycloalanopine, a cyclic opine from LS8, through synthesis and analog production. Rsc Medicinal Chemistry. 11: 528-531
Gómez-Mendoza DP, Lemos RP, Jesus I, et al. (2020) Moving pieces in a cellular puzzle: a cryptic peptide from the scorpion toxin Ts14 activates AKT and ERK signaling and decreases cardiac myocyte contractility via dephosphorylation of phospholamban. Journal of Proteome Research
Vuong W, Mosquera-Guagua F, Sanichar R, et al. (2019) Synthesis of Chiral Spin-Labeled Amino Acids. Organic Letters
Chiorean S, Antwi I, Carney DW, et al. (2019) Dissecting the binding interactions of teixobactin with the bacterial cell wall precursor lipid II. Chembiochem : a European Journal of Chemical Biology
Fischer C, Ahn YC, Vederas JC. (2019) Catalytic mechanism and properties of pyridoxal 5'-phosphate independent racemases: how enzymes alter mismatched acidity and basicity. Natural Product Reports
Fischer C, Lamer T, Wang W, et al. (2019) Plasma kallikrein cleaves and inactivates apelin-17: Palmitoyl- and PEG-extended apelin-17 analogs as metabolically stable blood pressure-lowering agents. European Journal of Medicinal Chemistry. 166: 119-124
Fischer C, Kwon M, Ro DK, et al. (2018) Isolation, expression and biochemical characterization of recombinant hyoscyamine-6β-hydroxylase from - tuning the scopolamine production. Medchemcomm. 9: 888-892
Acedo JZ, Chiorean S, Vederas JC, et al. (2018) The expanding structural variety among bacteriocins from Gram-positive bacteria. Fems Microbiology Reviews
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