Heinz G. Floss, Ph.D.
Affiliations: | 1966-1982 | Chemistry | Purdue University, West Lafayette, IN, United States |
| 1982-1987 | Chemistry | Ohio State University, Columbus, Columbus, OH | |
| 1988- | University of Washington, Seattle, Seattle, WA |
Area:
biosynthesis of antibiotics and related natural productsWebsite:
http://depts.washington.edu/chem/people/faculty/floss.htmlGoogle:
"Heinz Floss"Parents
Sign in to add mentor| Friedrich Weygand | grad student | 1961 | Technical University of Munich | |
| (Zur Biogenese der Mutterkornalkaloide und des Cumarins) | ||||
| Eric E. Conn | post-doc | 1962-1965 | UC Davis | |
Children
Sign in to add trainee| Laurence H. Hurley | grad student | 1970 | Purdue |
| Ming-Daw Tsai | grad student | 1978 | Purdue |
| Bradley S. Moore | grad student | 1994 | University of Washington |
| James L. Colony | grad student | 2000 | University of Washington |
| Yiding Hu | grad student | 2000 | University of Washington |
| Matthew G. McDonald | grad student | 2001 | University of Washington |
| Brian J. Carroll | grad student | 2003 | University of Washington |
| Christian Hertweck | post-doc | University of Washington | |
| Motomasa Kobayashi | post-doc | Ohio State | |
| Jason Micklefield | post-doc | University of Washington | |
| Rolf Müller | post-doc | University of Seattle | |
| Nigel D. Priestley | post-doc | University of Washington | |
| John C. Vederas | post-doc | 1976-1977 | Purdue |
| Ronald W. Woodard | post-doc | 1980 | Purdue |
| Andreas Kirschning | post-doc | 1989-1991 | University of Washington |
| Barrie Wilkinson | post-doc | 1994-1995 | University of Washington |
| Joern Piel | post-doc | 1998-1999 | University of Washington |
| Taifo Mahmud | post-doc | 1997-2000 | University of Washington |
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Publications
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| Rui Z, Ye M, Wang S, et al. (2012) Insights into a divergent phenazine biosynthetic pathway governed by a plasmid-born esmeraldin gene cluster. Chemistry & Biology. 19: 1116-25 |
| Eichner S, Eichner T, Floss HG, et al. (2012) Broad substrate specificity of the amide synthase in S. hygroscopicus--new 20-membered macrolactones derived from geldanamycin. Journal of the American Chemical Society. 134: 1673-9 |
| Eichner S, Knobloch T, Floss HG, et al. (2012) The interplay between mutasynthesis and semisynthesis: generation and evaluation of an ansamitocin library. Angewandte Chemie (International Ed. in English). 51: 752-7 |
| Wu Y, Kang Q, Shang G, et al. (2011) N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 12: 1759-66 |
| Floss HG, Yu TW, Arakawa K. (2011) The biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), the precursor of mC7N units in ansamycin and mitomycin antibiotics: a review. The Journal of Antibiotics. 64: 35-44 |
| Harmrolfs K, Brünjes M, Dräger G, et al. (2010) Cyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalyst. Chembiochem : a European Journal of Chemical Biology. 11: 2517-20 |
| Rui Z, Petrícková K, Skanta F, et al. (2010) Biochemical and genetic insights into asukamycin biosynthesis. The Journal of Biological Chemistry. 285: 24915-24 |
| Floss H, Leistner E. (2010) Obituary – Professor Dr. Detlef Gröger Planta Medica. 76: 1389-1389 |
| Hu Y, Floss HG. (2010) ChemInform Abstract: New Type II Manumycins Produced by Streptomyces nodosus ssp. asukaensis and Their Biosynthesis. Cheminform. 32: no-no |
| Eichner S, Floss HG, Sasse F, et al. (2009) New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1801-5 |