Stephen Todd Smale
Affiliations: | 1990- | Microbiology, Immunology, and Molecular Genetics | University of California, Los Angeles, Los Angeles, CA |
Area:
gene regulation during inflammatory and innate immune responses and during lymphocyte development and leukemogenesisWebsite:
https://people.healthsciences.ucla.edu/institution/personnel?personnel_id=45693Google:
"Stephen Todd Smale"Parents
Sign in to add mentor| Robert Tjian | grad student | 1986 | UC Berkeley | |
| (Simian Virus 40 DNA Replication: A Model for Eukaryotic DNA Synthesis.) | ||||
| David Baltimore | post-doc | Whitehead Institute (MIT) | ||
Children
Sign in to add trainee| Patricia Ernst | grad student | 1996 | UCLA |
| Hans D. Brightbill | grad student | 2000 | UCLA (Cell Biology Tree) |
| Amy S. Weinmann | grad student | 2000 | UCLA (Cell Biology Tree) |
| Michelle N. Bradley | grad student | 2003 | UCLA (Cell Biology Tree) |
| Aaron S. McCarty | grad student | 2003 | UCLA (Cell Biology Tree) |
| Liang Zhou | grad student | 2004 | UCLA (Cell Biology Tree) |
| Roger L. Ferrini | grad student | 2005 | UCLA (Cell Biology Tree) |
| Rupa Sridharan | grad student | 2006 | UCLA (Cell Biology Tree) |
| Jin Xu | grad student | 2008 | UCLA (Cell Biology Tree) |
| Scott D. Pope | grad student | 2009 | UCLA (Cell Biology Tree) |
| Dev M. Bhatt | grad student | 2011 | UCLA (Cell Biology Tree) |
| Abraham B. Chang | grad student | 2011 | UCLA (Cell Biology Tree) |
| Kevin R. Doty | grad student | 2012 | UCLA (Cell Biology Tree) |
| Miguel Edwards | grad student | 2014 | UCLA (Cell Biology Tree) |
| Justin B. Langerman | grad student | 2014 | UCLA (Cell Biology Tree) |
BETA: Related publications
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Publications
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| Daly AE, Chang AB, Purbey PK, et al. (2025) Stepwise neofunctionalization of the NF-κB family member Rel during vertebrate evolution. Nature Immunology. 26: 760-774 |
| Navarro HI, Daly AE, Rodriguez B, et al. (2025) NF-κB RelB suppresses the inflammatory gene expression programs of dendritic cells by competing with RelA for binding to target gene promoters. Cell Discovery. 11: 13 |
| Daly AE, Schiffman A, Hoffmann A, et al. (2024) Examining NF-κB genomic interactions by ChIP-seq and CUT&Tag. Biorxiv : the Preprint Server For Biology |
| Daly AE, Yeh G, Soltero S, et al. (2024) Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-κB p50-IκBζ pathway. Genes & Development |
| Purbey PK, Seo J, Paul MK, et al. (2024) Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity. Cell Reports. 43: 114289 |
| Feng AC, Thomas BJ, Purbey PK, et al. (2024) The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling. Immunity |
| Kagan JC, Rothenberg EV, Weiss A, et al. (2023) Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology. Trends in Immunology |
| Lo JH, Edwards M, Langerman J, et al. (2022) Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells. Genes & Development. 36: 1079-1095 |
| Aliyari SR, Ghaffari AA, Pernet O, et al. (2022) Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2. Acta Pharmaceutica Sinica. B |
| Blair L, Pattison MJ, Chakravarty P, et al. (2022) TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 208: 941-954 |