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Stephen J. Elledge

Affiliations: 
1989-2003 Baylor College of Medicine, Houston, TX 
 2003- Genetics Harvard Medical School, Boston, MA, United States 
Area:
response to DNA damage and regulation of the cell cycle
Website:
http://genetics.med.harvard.edu/faculty/elledge
Google:
"Stephen J. Elledge"
Bio:

http://www.nasonline.org/member-directory/members/3001995.html
http://genetics.med.harvard.edu/elledge/
http://dx.doi.org/10.1073/pnas.0400868101
http://hdl.handle.net/1721.1/67093

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Parents

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Graham C. Walker grad student 1983 MIT
 (Identification and characterization of genes involved in mutagenesis in Escherichia coli)
Ronald W. Davis post-doc 1984-1989 Stanford

Children

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Aiquan Chang grad student (Neurotree)
Natalya N Pavlova grad student Harvard Medical School
Zheng Zhou grad student 1994 Baylor College of Medicine
Anna Elizabeth Burrows grad student 2012 Harvard
Harry Benjamin Larman grad student 2012 MIT
Mohammad Dezfulian post-doc Harvard Medical School (Cell Biology Tree)
Kristopher T. Kahle post-doc Harvard Medical School (GenetiTree)
Yolanda Sanchez post-doc Baylor College of Medicine (Cell Biology Tree)
Mingxia Huang post-doc 1997 Baylor College of Medicine (Cell Biology Tree)
Jeffrey B. Bachant post-doc 1998 Baylor College of Medicine
David K. Cortez post-doc 2002 Baylor College of Medicine
Deanna M. Koepp post-doc 2002 Baylor College of Medicine
Yanchang Wang post-doc 2003 Baylor College of Medicine (Cell Biology Tree)
Lee Zou post-doc 2000-2003 Baylor College of Medicine
Dong Zhang post-doc 2006 Harvard Medical School (Neurotree)
Thomas Franklin Westbrook post-doc 2003-2007 Harvard Medical School (Cell Biology Tree)
Andrea Bredemeyer post-doc 2009 Harvard Medical School (Cell Biology Tree)
Guang Hu post-doc 2009 Harvard Medical School
Agata M. Smogorzewska post-doc 2005-2009 Harvard Medical School (Telomere and Telomerase Tree)
Jian Zhu post-doc 2012 Harvard Medical School (Cell Biology Tree)
Michael J. Emanuele post-doc 2013 Harvard Medical School
Xu Tan post-doc 2008-2014 Harvard Medical School
Lior Izhar post-doc 2010-2015 Harvard Medical School

Collaborators

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Joan W. Conaway collaborator 1998-1999 Harvard Medical School (Cell Biology Tree)
BETA: Related publications

Publications

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Kohlgruber AC, Dezfulian MH, Sie BM, et al. (2024) High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits. Nature Biotechnology
Dezfulian MH, Kula T, Pranzatelli T, et al. (2023) TScan-II: A genome-scale platform for the de novo identification of CD4 T cell epitopes. Cell
Zhang Z, Sie B, Chang A, et al. (2023) Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping. Molecular Cell. 83: 4191-4192
Zhang Z, Sie B, Chang A, et al. (2023) Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping. Molecular Cell. 83: 3377-3392.e6
Li S, Qian N, Jiang C, et al. (2022) Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation. Nature Communications. 13: 105
Meng Q, Xie S, Gray GK, et al. (2021) Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids. Journal For Immunotherapy of Cancer. 9
Adeyemi RO, Willis NA, Elia AEH, et al. (2021) The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair. Molecular Cell
Morgenlander WR, Henson S, Monaco D, et al. (2020) Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality. Medrxiv : the Preprint Server For Health Sciences
Shrock E, Fujimura E, Kula T, et al. (2020) Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. Science (New York, N.Y.)
Guerra SL, Maertens O, Kuzmickas R, et al. (2020) A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers. Cancer Cell
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