Jilian R. Melamed

Affiliations: 
2013-2018 Biomedical Engineering University of Delaware, Newark, DE, United States 
 2018- Chemical Engineering Carnegie Mellon University, Pittsburgh, PA 
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"Jilian Melamed"
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Doerfler R, Yerneni S, LoPresti S, et al. (2025) Maternal milk cell components are uptaken by infant liver macrophages via extracellular vesicle mediated transport. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 39: e70340
Chaudhary N, Kasiewicz LN, Newby AN, et al. (2024) Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d. Nature Biomedical Engineering
Omo-Lamai S, Zamora ME, Patel MN, et al. (2024) Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions. Advanced Materials (Deerfield Beach, Fla.). e2312026
Melamed JR, Yerneni SS, Arral ML, et al. (2023) Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer. Science Advances. 9: eade1444
Fein KC, Gleeson JP, Cochran K, et al. (2022) Long-term daily oral administration of intestinal permeation enhancers is safe and effective in mice. Bioengineering & Translational Medicine. 8: e10342
Doerfler R, Melamed JR, Whitehead KA. (2022) The Effect of Infant Gastric Digestion on Human Maternal Milk Cells. Molecular Nutrition & Food Research. e2200090
Lamson NG, Fein KC, Gleeson JP, et al. (2022) The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207829119
Melamed JR, Hajj KA, Chaudhary N, et al. (2021) Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society
Iqbal S, Luo B, Melamed JR, et al. (2021) Critical Evaluation of Different Lysosomal Labeling Methods Used to Analyze RNA Nanocarrier Trafficking in Cells. Bioconjugate Chemistry
Hajj KA, Melamed JR, Chaudhary N, et al. (2020) A potent branched-tail lipid nanoparticle enables multiplexed mRNA delivery and gene editing in vivo. Nano Letters
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