Laura M. Bohn, Ph.D.

Affiliations: 
2003-2008 The Ohio State University College of Medicine 
 2009- Molecular Therapeutics & Neuroscience Scripps Research Institute Florida 
Area:
Pharmacology, Neuropharmacology, Neuroscience
Website:
http://www.scripps.edu/research/faculty/bohn
Google:
"Laura Bohn"
Cross-listing: Neurotree

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Publications

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Trojniak AE, Dang VQ, Czekner KM, et al. (2024) Synthesis and evaluation of 3,4,5-trisubstituted triazoles as G protein-biased kappa opioid receptor agonists. European Journal of Medicinal Chemistry. 276: 116627
Brust CA, Swanson MA, Bohn LM. (2023) Structural and functional insights into the G protein-coupled receptors: CB1 and CB2. Biochemical Society Transactions. 51: 1533-1543
Hill SJ, Dao N, Dang VQ, et al. (2023) A Route to Potent, Selective, and Biased Salvinorin Chemical Space. Acs Central Science. 9: 1567-1574
Acevedo-Canabal A, Grim TW, Schmid CL, et al. (2023) Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine. Biomolecules. 13
Shevick SL, Freeman SM, Tong G, et al. (2022) Asymmetric Syntheses of (+)- and (-)-Collybolide Enable Reevaluation of -Opioid Receptor Agonism. Acs Central Science. 8: 948-954
Brust CA, Ho JH, Stahl E, et al. (2022) Functional analysis of key residues involved in CB1 and CB2 activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Stahl E, Schmid CL, Acevedo-Canabal A, et al. (2022) Irreversible and noncompetitive mu opioid receptor agonists. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Ma H, Brust T, Frankowski KJ, et al. (2022) Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance. Acs Chemical Neuroscience. 13: 1315-1332
Kolb P, Kenakin T, Alexander SPH, et al. (2022) Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX. British Journal of Pharmacology
Stahl EL, Schmid CL, Acevedo-Canabal A, et al. (2021) G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists. Proceedings of the National Academy of Sciences of the United States of America. 118
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