Jennifer M. Heemstra, Ph.D. - Publications

Affiliations: 
2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
synthesis and study of macromolecules

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Quillin AL, Karloff DB, Ayele TM, Flores TF, Chen G, McEachin ZT, Valdez-Sinon AN, Heemstra JM. Imaging and Tracking RNA in Live Mammalian Cells via Fluorogenic Photoaffinity Labeling. Acs Chemical Biology. PMID 39953970 DOI: 10.1021/acschembio.4c00848  0.416
2024 Quillin AL, Arnould B, Knutson SD, Flores TF, Heemstra JM. EndoVIA for quantifying A-to-I editing and mapping the subcellular localization of edited transcripts. Methods in Enzymology. 710: 99-130. PMID 39870453 DOI: 10.1016/bs.mie.2024.11.029  0.772
2024 Karloff DB, Stubbs RT, Ibukun OJ, Knutson SD, James SH, Heemstra JM. Glyoxal Caging of Nucleoside Antivirals toward Self-Activating, Extended-Release Prodrugs. Journal of the American Chemical Society. PMID 39412404 DOI: 10.1021/jacs.4c08371  0.693
2024 Quillin AL, Arnould B, Knutson SD, Heemstra JM. Spatial Visualization of A-to-I Editing in Cells Using Endonuclease V Immunostaining Assay (EndoVIA). Acs Central Science. 10: 1396-1405. PMID 39071059 DOI: 10.1021/acscentsci.4c00444  0.775
2024 Quillin AL, Arnould B, Knutson SD, Heemstra JM. Spatial visualization of A-to-I Editing in cells using Endonuclease V Immunostaining Assay (EndoVIA). Biorxiv : the Preprint Server For Biology. PMID 38496620 DOI: 10.1101/2024.03.04.583344  0.775
2023 Argueta-Gonzalez H, Swenson CS, Skowron KJ, Heemstra JM. Elucidating Sequence-Assembly Relationships for Bilingual PNA Biopolymers. Acs Omega. 8: 37442-37450. PMID 37841192 DOI: 10.1021/acsomega.3c05528  0.706
2023 Manuel BA, Das S, Sanford A, Jenkins MC, Finn MG, Heemstra JM. Modular Catalysis: Aptamer Enhancement of Enzyme Kinetics in a Nanoparticle Reactor. Biomacromolecules. PMID 36988581 DOI: 10.1021/acs.biomac.3c00144  0.285
2023 Arnould B, Quillin AL, Heemstra JM. Tracking the Message: Applying Single Molecule Localization Microscopy to Cellular RNA Imaging. Chembiochem : a European Journal of Chemical Biology. e202300049. PMID 36857087 DOI: 10.1002/cbic.202300049  0.495
2022 Swenson CS, Argueta-Gonzalez HS, Sterling SA, Robichaux R, Knutson SD, Heemstra JM. Forced Intercalation Peptide Nucleic Acid Probes for the Detection of an Adenosine-to-Inosine Modification. Acs Omega. 8: 238-248. PMID 36643573 DOI: 10.1021/acsomega.2c03568  0.78
2022 Patterson KN, Romero-Reyes MA, Heemstra JM. Fluorescence Quenching of Xanthene Dyes during Amide Bond Formation Using DMTMM. Acs Omega. 7: 33046-33053. PMID 36157719 DOI: 10.1021/acsomega.2c03085  0.36
2022 Argueta-Gonzalez HS, Swenson CS, Song G, Heemstra JM. Stimuli-responsive assembly of bilingual peptide nucleic acids. Rsc Chemical Biology. 3: 1035-1043. PMID 35974999 DOI: 10.1039/d2cb00020b  0.733
2022 Felix AS, Quillin AL, Mousavi S, Heemstra JM. Harnessing Nature's Molecular Recognition Capabilities to Map and Study RNA Modifications. Accounts of Chemical Research. 55: 2271-2279. PMID 35900335 DOI: 10.1021/acs.accounts.2c00287  0.517
2022 Sanford AA, Manuel BA, Romero-Reyes MA, Heemstra JM. Combating small molecule environmental contaminants: detection and sequestration using functional nucleic acids. Chemical Science. 13: 7670-7684. PMID 35865900 DOI: 10.1039/d2sc00117a  0.37
2022 Manuel BA, Sterling SA, Sanford AA, Heemstra JM. Systematically Modulating Aptamer Affinity and Specificity by Guanosine-to-Inosine Substitution. Analytical Chemistry. 94: 6436-6440. PMID 35435665 DOI: 10.1021/acs.analchem.2c00422  0.355
2021 Karloff DB, Heemstra JM. Sweet sensation: Developing a single-cell fluorescent reporter of glycolytic heterogeneity. Cell Chemical Biology. 28: 1539-1541. PMID 34798034 DOI: 10.1016/j.chembiol.2021.10.013  0.344
2021 Sanford AA, Rangel AE, Feagin TA, Lowery RG, Argueta-Gonzalez HS, Heemstra JM. RE-SELEX: restriction enzyme-based evolution of structure-switching aptamer biosensors. Chemical Science. 12: 11692-11702. PMID 34659704 DOI: 10.1039/d1sc02715h  0.341
2021 Romero-Reyes MA, Heemstra JM. Sequestration and Removal of Multiple Small-Molecule Contaminants Using an Optimized Aptamer-Based Ultrafiltration System. Bioconjugate Chemistry. PMID 34478279 DOI: 10.1021/acs.bioconjchem.1c00344  0.329
2021 Swenson CS, Lackey HH, Reece EJ, Harris JM, Heemstra JM, Peterson EM. Evaluating the effect of ionic strength on PNA:DNA duplex formation kinetics. Rsc Chemical Biology. 2: 1249-1256. PMID 34458838 DOI: 10.1039/d1cb00025j  0.72
2021 Knutson SD, Arthur RA, Johnston HR, Heemstra J. Direct Immunodetection of Global A-to-I RNA Editing Activity with a Chemiluminescent Bioassay. Angewandte Chemie (International Ed. in English). PMID 33979483 DOI: 10.1002/anie.202102762  0.792
2021 Knutson SD, Heemstra JM. Protein-based molecular recognition tools for detecting and profiling RNA modifications. Current Opinion in Structural Biology. 69: 1-10. PMID 33445115 DOI: 10.1016/j.sbi.2020.12.006  0.792
2020 Knutson SD, Sanford AA, Swenson CS, Korn MM, Manuel BA, Heemstra JM. Thermoreversible Control of Nucleic Acid Structure and Function with Glyoxal Caging. Journal of the American Chemical Society. 142: 17766-17781. PMID 33017148 DOI: 10.1021/jacs.0c08996  0.799
2020 Ayele TM, Knutson SD, Heemstra JM. Covalent live-cell labeling of proteins using a photoreactive fluorogen. Methods in Enzymology. 639: 355-377. PMID 32475409 DOI: 10.1016/Bs.Mie.2020.04.019  0.752
2020 Knutson SD, Heemstra JM. EndoVIPER-seq for Improved Detection of A-to-I Editing Sites in Cellular RNA. Current Protocols in Chemical Biology. 12: e82. PMID 32469473 DOI: 10.1002/Cpch.82  0.795
2020 Knutson SD, Korn MM, Johnson RP, Monteleone LR, Dailey DM, Swenson CS, Beal PA, Heemstra J. Chemical Profiling of A-to-I RNA Editing Using a Click-Compatible Phenylacrylamide. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32428320 DOI: 10.1002/Chem.202001667  0.806
2020 Lackey HH, Peterson EM, Harris JM, Heemstra JM. Probing the Mechanism of Structure-Switching Aptamer Assembly by Super-Resolution Localization of Individual DNA Molecules. Analytical Chemistry. PMID 32297506 DOI: 10.1021/Acs.Analchem.9B05563  0.458
2020 Knutson SD, Arthur RA, Johnston HR, Heemstra JM. Selective Enrichment of A-to-I Edited Transcripts from Cellular RNA Using Endonuclease V. Journal of the American Chemical Society. PMID 32109061 DOI: 10.1021/Jacs.9B13406  0.798
2020 Swenson CS, Heemstra JM. Peptide nucleic acids harness dual information codes in a single molecule. Chemical Communications (Cambridge, England). 56: 1926-1935. PMID 32009137 DOI: 10.1039/C9Cc09905K  0.738
2020 Heemstra JM. A Scientist's Guide to Social Media. Acs Central Science. 6: 1-5. PMID 31989017 DOI: 10.1021/Acscentsci.9B01273  0.29
2020 Lackey HH, Chen Z, Harris JM, Peterson EM, Heemstra JM. Single-Molecule Kinetics Show DNA Pyrimidine Content Strongly Affects RNA:DNA and TNA:DNA Heteroduplex Dissociation Rates. Acs Synthetic Biology. PMID 31909980 DOI: 10.1021/Acssynbio.9B00471  0.515
2020 Muniz MI, Lackey HH, Heemstra JM, Weber G. DNA/TNA mesoscopic modeling of melting temperatures suggests weaker hydrogen bonding of CG than in DNA/RNA Chemical Physics Letters. 749: 137413. DOI: 10.1016/J.Cplett.2020.137413  0.477
2019 Swenson CS, Velusamy A, Argueta-Gonzalez HS, Heemstra JM. Bilingual Peptide Nucleic Acids: Encoding the Languages of Nucleic Acids and Proteins in a Single Self-Assembling Biopolymer. Journal of the American Chemical Society. PMID 31711285 DOI: 10.1021/Jacs.9B09146  0.751
2019 Heemstra JM. Self-Care Is Not the Enemy of Performance. Chembiochem : a European Journal of Chemical Biology. PMID 31211892 DOI: 10.1002/Cbic.201900285  0.314
2019 Ayele T, Knutson SD, Ellipilli S, Hwang H, Heemstra JM. Fluorogenic Photoaffinity Labeling of Proteins in Living Cells. Bioconjugate Chemistry. PMID 30978287 DOI: 10.1021/Acs.Bioconjchem.9B00203  0.746
2019 Lackey H, Peterson EM, Chen Z, Harris JM, Heemstra JM. Thermostability Trends of TNA:DNA Duplexes Reveal Strong Purine Dependence. Acs Synthetic Biology. PMID 30964657 DOI: 10.1021/Acssynbio.9B00028  0.436
2019 Henry MA, Shorter S, Charkoudian L, Heemstra JM, Corwin LA. FAIL Is Not a Four-Letter Word: A Theoretical Framework for Exploring Undergraduate Students' Approaches to Academic Challenge and Responses to Failure in STEM Learning Environments. Cbe Life Sciences Education. 18: ar11. PMID 30821602 DOI: 10.1187/Cbe.18-06-0108  0.315
2019 Romero-Reyes MA, Heemstra JM. Small-Molecule Sequestration Using Aptamer-Functionalized Membranes Acs Materials Letters. 1: 568-572. DOI: 10.1021/acsmaterialslett.9b00288  0.272
2018 Wilson CJ, Bommarius AS, Champion JA, Chernoff YO, Lynn DG, Paravastu AK, Liang C, Hsieh MC, Heemstra JM. Biomolecular Assemblies: Moving from Observation to Predictive Design. Chemical Reviews. PMID 30281290 DOI: 10.1021/Acs.Chemrev.8B00038  0.404
2018 Morris FD, Peterson EM, Heemstra JM, Harris JM. Single-Molecule Kinetic Investigation of Cocaine-Dependent Split-Aptamer Assembly. Analytical Chemistry. PMID 30280568 DOI: 10.1021/Acs.Analchem.8B03637  0.442
2018 Knutson SD, Ayele TM, Heemstra JM. Chemical Labeling and Affinity Capture of Inosine-Containing RNAs Using Acrylamidofluorescein. Bioconjugate Chemistry. PMID 30148626 DOI: 10.1021/Acs.Bioconjchem.8B00541  0.804
2018 Tan Z, Heemstra JM. High-Throughput Measurement of Small-Molecule Enantiopurity by Using Flow Cytometry. Chembiochem : a European Journal of Chemical Biology. PMID 30126025 DOI: 10.1002/Cbic.201800341  0.437
2018 Rangel AE, Chen Z, Ayele TM, Heemstra JM. In vitro selection of an XNA aptamer capable of small-molecule recognition. Nucleic Acids Research. PMID 30085205 DOI: 10.1093/Nar/Gky667  0.45
2018 Ellipilli S, Phillips JD, Heemstra JM. Synthesis of comb-shaped DNA using a non-nucleosidic branching phosphoramidite. Organic & Biomolecular Chemistry. PMID 29881861 DOI: 10.1039/C8Ob00626A  0.769
2018 Tan Z, Heemstra JM. Cover Feature: High‐Throughput Measurement of Small‐Molecule Enantiopurity by Using Flow Cytometry (ChemBioChem 17/2018) Chembiochem. 19: 1794-1794. DOI: 10.1002/Cbic.201800454  0.3
2017 Haas KL, Heemstra JM, Medema M, Charkoudian LK. Collaborating with Undergraduates to Contribute to Biochemistry Community Resources. Biochemistry. PMID 29048882 DOI: 10.1021/Acs.Biochem.7B00872  0.334
2016 Hanson WM, Chen Z, Jackson LK, Attaf M, Sewell AK, Heemstra JM, Phillips JD. Reversible Oligonucleotide Chain Blocking Enables Bead Capture and Amplification of T-Cell Receptor α and β Chain mRNAs. Journal of the American Chemical Society. PMID 27478996 DOI: 10.1021/Jacs.6B04465  0.432
2016 Chen Z, Meek KN, Rangel AE, Heemstra JM. Synthesis and polymerase incorporation of β,γ-modified α-l-threofuranosyl thymine triphosphate mimics. Bioorganic & Medicinal Chemistry Letters. PMID 27422338 DOI: 10.1016/J.Bmcl.2016.07.008  0.342
2016 Davis DL, Price EK, Aderibigbe SO, Larkin MX, Barlow ED, Chen R, Ford LC, Gray ZT, Gren SH, Jin Y, Keddington KS, Kent AD, Kim D, Lewis A, Marrouche RS, ... ... Heemstra JM, et al. Effect of Buffer Conditions and Organic Co-Solvents on the Rate of Strain-Promoted Azide-Alkyne Cycloaddition. The Journal of Organic Chemistry. PMID 27387821 DOI: 10.1021/Acs.Joc.6B01112  0.335
2016 Tan Z, Feagin TA, Heemstra JM. Temporal Control of Aptamer Biosensors Using Covalent Self-Caging to Shift Equilibrium. Journal of the American Chemical Society. PMID 27159220 DOI: 10.1021/Jacs.6B00934  0.395
2016 Meek KN, Rangel AE, Heemstra JM. Enhancing aptamer function and stability via in vitro selection using modified nucleic acids. Methods (San Diego, Calif.). PMID 27012179 DOI: 10.1016/J.Ymeth.2016.03.008  0.53
2016 Perera RT, Fleming AM, Peterson AM, Heemstra JM, Burrows CJ, White HS. Unzipping of A-Form DNA-RNA, A-Form DNA-PNA, and B-Form DNA-DNA in the α-Hemolysin Nanopore. Biophysical Journal. 110: 306-314. PMID 26789754 DOI: 10.1016/J.Bpj.2015.11.020  0.468
2016 Heemstra JM. Profile: early excellence in physical organic chemistry Journal of Physical Organic Chemistry. 29: 380-381. DOI: 10.1002/poc.3593  0.202
2015 Heemstra JM. Learning from the unexpected in life and DNA self-assembly. Beilstein Journal of Organic Chemistry. 11: 2713-20. PMID 26877793 DOI: 10.3762/Bjoc.11.292  0.346
2015 Peterson AM, Jahnke FM, Heemstra JM. Modulating the Substrate Selectivity of DNA Aptamers Using Surfactants. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 11769-73. PMID 26465173 DOI: 10.1021/Acs.Langmuir.5B02818  0.474
2015 Anderton GI, Bangerter AS, Davis TC, Feng Z, Furtak AJ, Larsen JO, Scroggin TL, Heemstra JM. Accelerating Strain-Promoted Azide-Alkyne Cycloaddition Using Micellar Catalysis. Bioconjugate Chemistry. PMID 26056848 DOI: 10.1021/Acs.Bioconjchem.5B00274  0.382
2015 Feagin TA, Olsen DP, Headman ZC, Heemstra JM. High-throughput enantiopurity analysis using enantiomeric DNA-based sensors. Journal of the American Chemical Society. 137: 4198-206. PMID 25747268 DOI: 10.1021/Jacs.5B00923  0.461
2015 Peterson AM, Heemstra JM. Controlling self-assembly of DNA-polymer conjugates for applications in imaging and drug delivery. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 7: 282-97. PMID 25327363 DOI: 10.1002/Wnan.1309  0.413
2015 Peterson AM, Tan Z, Kimbrough EM, Heemstra JM. 3,3′-Dioctadecyloxacarbocyanine perchlorate (DiO) as a fluorogenic probe for measurement of critical micelle concentration Analytical Methods. 7: 6877-6882. DOI: 10.1039/C5Ay01444A  0.366
2014 Sharma AK, Plant JJ, Rangel AE, Meek KN, Anamisis AJ, Hollien J, Heemstra JM. Fluorescent RNA labeling using self-alkylating ribozymes. Acs Chemical Biology. 9: 1680-4. PMID 24896502 DOI: 10.1021/Cb5002119  0.702
2014 De Costa NT, Heemstra JM. Differential DNA and RNA sequence discrimination by PNA having charged side chains. Bioorganic & Medicinal Chemistry Letters. 24: 2360-3. PMID 24731279 DOI: 10.1016/J.Bmcl.2014.03.059  0.47
2014 Sharma AK, Plant JJ, Rangel AE, Meek KN, Hollien J, Heemstra JM. Harnessing RNA-small molecule recognition for covalent RNA modification Collection of Czechoslovak Chemical Communications. 14: 80-83. DOI: 10.1135/Css201414080  0.674
2013 Kent AD, Spiropulos NG, Heemstra JM. General approach for engineering small-molecule-binding DNA split aptamers. Analytical Chemistry. 85: 9916-23. PMID 24033257 DOI: 10.1021/Ac402500N  0.473
2013 De Costa NT, Heemstra JM. Evaluating the effect of ionic strength on duplex stability for PNA having negatively or positively charged side chains. Plos One. 8: e58670. PMID 23484047 DOI: 10.1371/Journal.Pone.0058670  0.47
2012 Spiropulos NG, Heemstra JM. Templating effect in DNA proximity ligation enables use of non-bioorthogonal chemistry in biological fluids. Artificial Dna, Pna & Xna. 3: 123-8. PMID 23370267 DOI: 10.4161/adna.23842  0.373
2012 Bag SS, Heemstra JM, Saito Y, Chenoweth DM. Expansion of the genetic alphabet: unnatural nucleobases and their applications. Journal of Nucleic Acids. 2012: 718582. PMID 23316342 DOI: 10.1155/2012/718582  0.739
2012 Feagin TA, Shah NI, Heemstra JM. Convenient and scalable synthesis of fmoc-protected Peptide nucleic Acid backbone. Journal of Nucleic Acids. 2012: 354549. PMID 22848796 DOI: 10.1155/2012/354549  0.422
2012 Sharma AK, Kent AD, Heemstra JM. Enzyme-linked small-molecule detection using split aptamer ligation. Analytical Chemistry. 84: 6104-9. PMID 22715870 DOI: 10.1021/Ac300997Q  0.602
2012 Stowell RR, Heemstra JM, Schulte DD, Sheffield RE, Wheeler EF, Janni KA. Highlights of the Air Quality Education in Animal Agriculture project Asabe - 9th International Livestock Environment Symposium 2012, Iles 2012. 692-700.  0.172
2011 Sharma AK, Heemstra JM. Small-molecule-dependent split aptamer ligation. Journal of the American Chemical Society. 133: 12426-9. PMID 21761903 DOI: 10.1021/ja205518e  0.542
2009 Heemstra JM, Liu DR. Templated synthesis of peptide nucleic acids via sequence-selective base-filling reactions. Journal of the American Chemical Society. 131: 11347-9. PMID 19722647 DOI: 10.1021/Ja904712T  0.576
2009 Kowtoniuk WE, Shen Y, Heemstra JM, Agarwal I, Liu DR. A chemical screen for biological small molecule-RNA conjugates reveals CoA-linked RNA. Proceedings of the National Academy of Sciences of the United States of America. 106: 7768-73. PMID 19416889 DOI: 10.1073/Pnas.0900528106  0.801
2007 Heemstra JM, Kerrigan SA, Doerge DR, Helferich WG, Boulanger WA. Erratum: Total synthesis of (S)-equol (Organic Letters (2006) 8, (5443)) Organic Letters. 9. DOI: 10.1021/Ol062772R  0.327
2006 Heemstra JM, Kerrigan SA, Doerge DR, Helferich WG, Boulanger WA. Total synthesis of (S)-equol. Organic Letters. 8: 5441-3. PMID 17107042 DOI: 10.1021/Ol0620444  0.349
2006 Stone MT, Heemstra JM, Moore JS. The chain-length dependence test. Accounts of Chemical Research. 39: 11-20. PMID 16411735 DOI: 10.1021/Ar0501267  0.672
2004 Heemstra JM, Moore JS. Enhanced methylation rate within a foldable molecular receptor. The Journal of Organic Chemistry. 69: 9234-7. PMID 15609960 DOI: 10.1021/Jo048506D  0.477
2004 Heemstra JM, Moore JS. Helix stabilization through pyridinium-pi interactions. Chemical Communications (Cambridge, England). 1480-1. PMID 15216340 DOI: 10.1039/B405980H  0.465
2004 Goto H, Heemstra JM, Hill DJ, Moore JS. Single-site modifications and their effect on the folding stability of m-phenylene ethynylene oligomers. Organic Letters. 6: 889-92. PMID 15012057 DOI: 10.1021/Ol036376+  0.52
2004 Heemstra JM, Moore JS. Pyridine-containing m-phenylene ethynylene oligomers having tunable basicities. Organic Letters. 6: 659-62. PMID 14986943 DOI: 10.1021/Ol0363016  0.497
2004 Heemstra JM, Moore JS. Folding-promoted methylation of a helical DMAP analogue. Journal of the American Chemical Society. 126: 1648-9. PMID 14871092 DOI: 10.1021/Ja031842B  0.481
2004 Heemstra JM, Moore JS. A novel indicator series for measuring pKa values in acetonitrile Tetrahedron. 60: 7287-7292. DOI: 10.1016/J.Tet.2004.05.019  0.46
2004 Heemstra JM, Moore JS. Helix stabilization through pyridinium-π interactions Chemical Communications. 10: 1480-1481.  0.211
1999 Heemstra JM, Kronberg SL, Neiger RD, Pruitt RJ. Behavioral, nutritional, and toxicological responses of cattle to ensiled leafy spurge. Journal of Animal Science. 77: 600-10. PMID 10229355  0.222
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