Stephanie K. Dougan, Ph.D. - Publications

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu EJK, Smith BE, Conce Alberto WD, Walsh MJ, Lim B, Hoffman MT, Qiang L, Dong J, Garmilla A, Zhao QH, Perez CR, Gaglione SA, Dobson CS, Dougan M, Dougan SK, et al. Peptide-MHC-targeted retroviruses enable expansion and gene delivery to tumor-specific T cells. Biorxiv : the Preprint Server For Biology. PMID 39345591 DOI: 10.1101/2024.09.18.613594  0.345
2024 Kureshi CT, Dougan M, Dougan SK. Anti-LAG-3 boosts CD8 T cell effector function. Cell. 187: 4144-4146. PMID 39121844 DOI: 10.1016/j.cell.2024.07.004  0.328
2024 Oberstein PE, Dias Costa A, Kawaler EA, Cardot-Ruffino V, Rahma OE, Beri N, Singh H, Abrams TA, Biller LH, Cleary J, Enzinger P, Huffman BM, McCleary NJ, Perez KJ, Rubinson DA, ... ... Dougan SK, et al. Blockade of IL-1β and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor. Cancer Immunology Research. PMID 38990554 DOI: 10.1158/2326-6066.CIR-23-1073  0.327
2024 Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, et al. Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. PMID 38336833 DOI: 10.1038/s41586-024-07164-y  0.375
2023 Kureshi R, Bello E, Kureshi CTS, Walsh MJ, Lippert V, Hoffman MT, Dougan M, Longmire T, Wichroski M, Dougan SK. DGKα/ζ inhibition lowers the TCR affinity threshold and potentiates antitumor immunity. Science Advances. 9: eadk1853. PMID 38000024 DOI: 10.1126/sciadv.adk1853  0.412
2023 Kurmi K, Liang D, van de Ven R, Georgiev P, Gassaway BM, Han S, Notarangelo G, Harris IS, Yao CH, Park JS, Hu SH, Peng J, Drijvers JM, Boswell S, Sokolov A, ... Dougan SK, et al. Metabolic modulation of mitochondrial mass during CD4 T cell activation. Cell Chemical Biology. PMID 37716347 DOI: 10.1016/j.chembiol.2023.08.008  0.312
2023 Ventre KS, Roehle K, Bello E, Bhuiyan AM, Biary T, Crowley SJ, Bruck PT, Heckler M, Lenehan PJ, Ali LR, Stump CT, Lippert V, Clancy-Thompson E, Conce Alberto WD, Hoffman MT, ... ... Dougan SK, et al. cIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 36881882 DOI: 10.4049/jimmunol.2200646  0.416
2022 Quijano-Rubio A, Bhuiyan AM, Yang H, Leung I, Bello E, Ali LR, Zhangxu K, Perkins J, Chun JH, Wang W, Lajoie MJ, Ravichandran R, Kuo YH, Dougan SK, Riddell SR, et al. A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy. Nature Biotechnology. PMID 36316485 DOI: 10.1038/s41587-022-01510-z  0.321
2021 Stump CT, Roehle K, Manjarrez Orduno N, Dougan SK. Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer. Open Biology. 11: 210245. PMID 34784792 DOI: 10.1098/rsob.210245  0.311
2021 Roehle K, Qiang L, Ventre KS, Heid D, Ali LR, Lenehan P, Heckler M, Crowley SJ, Stump CT, Ro G, Godicelj A, Bhuiyan AM, Yang A, Quiles Del Rey M, Biary T, ... ... Dougan SK, et al. cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Science Translational Medicine. 13. PMID 34011631 DOI: 10.1126/scitranslmed.abf5058  0.356
2021 Heckler M, Ali LR, Clancy-Thompson E, Qiang L, Ventre KS, Lenehan P, Roehle K, Luoma A, Boelaars K, Peters V, McCreary J, Boschert T, Wang ES, Suo S, Marangoni F, ... ... Dougan SK, et al. Inhibition of CDK4/6 promotes CD8 T-cell memory formation. Cancer Discovery. PMID 33941591 DOI: 10.1158/2159-8290.CD-20-1540  0.339
2020 Luoma AM, Suo S, Williams HL, Sharova T, Sullivan K, Manos M, Bowling P, Hodi FS, Rahma O, Sullivan RJ, Boland GM, Nowak JA, Dougan SK, Dougan M, Yuan GC, et al. Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy. Cell. PMID 32603654 DOI: 10.1016/J.Cell.2020.06.001  0.474
2020 Crowley SJ, Bruck PT, Bhuiyan MA, Mitchell-Gears A, Walsh MJ, Zhangxu K, Ali LR, Jeong HJ, Ingram JR, Knipe DM, Ploegh HL, Dougan M, Dougan SK. Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH. Open Biology. 10: 190235. PMID 32019478 DOI: 10.1098/Rsob.190235  0.399
2019 Dougan SK, Dougan M. SMAC mimetics throw a molecular switch to control T17 responses. Science Signaling. 12. PMID 31455724 DOI: 10.1126/Scisignal.Aay3986  0.404
2019 Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The Embo Journal. 38: e101260. PMID 31304630 DOI: 10.15252/Embj.2018101260  0.409
2019 Dougan M, Dougan SK. Programmable bacteria as cancer therapy. Nature Medicine. PMID 31270505 DOI: 10.1038/S41591-019-0513-4  0.333
2019 Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The Embo Journal. PMID 31152007 DOI: 10.15252/embj.2018101260  0.3
2019 Balachandran VP, Beatty GL, Dougan SK. Broadening the impact of immunotherapy to pancreatic cancer: Challenges and opportunities. Gastroenterology. PMID 30660727 DOI: 10.1053/J.Gastro.2018.12.038  0.303
2019 Dougan SK. Abstract I09: Tumor-specific T cells reprogram mononuclear phagocytes for destruction of checkpoint blockade-resistant pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-I09  0.479
2019 Sheahan A, Morel K, Burkhart D, Baca S, Labbè D, Roehle K, Calagua C, Ye H, Galbo P, Panja S, Mitrofanova A, Hamid A, Kibel A, Choudhury A, Pomerantz M, ... ... Dougan S, et al. Abstract B006: Targeting EZH2 increases therapeutic efficacy of PD-1 blockade in models of prostate cancer Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B006  0.332
2018 Clancy-Thompson E, Devlin CA, Tyler PM, Servos MM, Ali LR, Ventre KS, Bhuiyan MA, Bruck PT, Birnbaum M, Dougan SK. Altered binding of tumor antigenic peptides to MHC class I affects CD8 T cell effector responses. Cancer Immunology Research. PMID 30352798 DOI: 10.2210/Pdb6Mp0/Pdb  0.468
2018 Yasmin-Karim S, Bruck PT, Moreau M, Kunjachan S, Chen GZ, Kumar R, Grabow S, Dougan SK, Ngwa W. Radiation and Local Anti-CD40 Generate an Effective Vaccine in Preclinical Models of Pancreatic Cancer. Frontiers in Immunology. 9: 2030. PMID 30245691 DOI: 10.3389/Fimmu.2018.02030  0.413
2018 Ito Y, Ashenberg O, Pyrdol J, Luoma AM, Rozenblatt-Rosen O, Hofree M, Christian E, Ferrari de Andrade L, Tay RE, Teyton L, Regev A, Dougan SK, Wucherpfennig KW. Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity. The Journal of Experimental Medicine. PMID 30185635 DOI: 10.1084/Jem.20180300  0.328
2018 Lin YC, Pecetta S, Steichen JM, Kratochvil S, Melzi E, Arnold J, Dougan SK, Wu L, Kirsch KH, Nair U, Schief WR, Batista FD. One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice. The Embo Journal. PMID 30087111 DOI: 10.15252/Embj.201899243  0.329
2018 Heckler M, Dougan SK. Unmasking Pancreatic Cancer: Epitope Spreading After Single Antigen Chimeric Antigen Receptor T-Cell Therapy in a Human Phase I Trial. Gastroenterology. PMID 29885301 DOI: 10.1053/J.Gastro.2018.06.023  0.393
2018 Dougan SK, Dougan M. Regulation of innate and adaptive antitumor immunity by IAP antagonists. Immunotherapy. PMID 29807457 DOI: 10.2217/Imt-2017-0185  0.436
2018 Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA. The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy. Science Translational Medicine. 10. PMID 29643230 DOI: 10.1126/Scitranslmed.Aan3464  0.305
2018 Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, ... Dougan SK, et al. Anti-CTLA-4 therapy requires an Fc domain for efficacy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581255 DOI: 10.1073/Pnas.1801524115  0.331
2018 Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK. Targeting cytokine therapy to the pancreatic tumor microenvironment using PD-L1 specific VHHs. Cancer Immunology Research. PMID 29459478 DOI: 10.1158/2326-6066.Cir-17-0495  0.341
2017 Jeong HJ, Abhiraman GC, Story CM, Ingram JR, Dougan SK. Generation of Ca2+-independent sortase A mutants with enhanced activity for protein and cell surface labeling. Plos One. 12: e0189068. PMID 29200433 DOI: 10.1371/Journal.Pone.0189068  0.319
2017 Dougan SK. The Pancreatic Cancer Microenvironment. Cancer Journal (Sudbury, Mass.). 23: 321-325. PMID 29189327 DOI: 10.1097/Ppo.0000000000000288  0.381
2017 Clancy-Thompson E, Ali L, Bruck PT, Exley MA, Blumberg RS, Dranoff G, Dougan M, Dougan SK. IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells. Cancer Immunology Research. PMID 29187357 DOI: 10.1158/2326-6066.Cir-17-0490  0.575
2017 Zeissig S, Peuker K, Iyer S, Gensollen T, Dougan SK, Olszak T, Kaser A, Blumberg RS. CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28893990 DOI: 10.1073/Pnas.1701428114  0.593
2017 Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M. Localized CD47 blockade enhances immunotherapy for murine melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874561 DOI: 10.1073/Pnas.1710776114  0.383
2017 Clancy-Thompson E, Chen GZ, Tyler PM, Servos MM, Barisa M, Brennan PJ, Ploegh HL, Dougan SK. Monoclonal Invariant NKT (iNKT) Cell Mice Reveal a Role for Both Tissue of Origin and the TCR in Development of iNKT Functional Subsets. Journal of Immunology (Baltimore, Md. : 1950). PMID 28576977 DOI: 10.4049/Jimmunol.1700214  0.38
2017 Dougan M, Dougan SK. Targeting Immunotherapy to the Tumor Microenvironment. Journal of Cellular Biochemistry. PMID 28332219 DOI: 10.1002/Jcb.26005  0.305
2017 Pishesha N, Bilate AM, Wibowo MC, Huang NJ, Li Z, Dhesycka R, Bousbaine D, Li H, Patterson HC, Dougan SK, Maruyama T, Lodish HF, Ploegh HL. Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270614 DOI: 10.1073/Pnas.1701746114  0.442
2017 Tyler PM, Servos MM, de Vries RC, Klebanov B, Kashyap T, Sacham S, Landesman Y, Dougan M, Dougan SK. Clinical dosing regimen of selinexor maintains normal immune homeostasis and T cell effector function in mice: implications for combination with immunotherapy. Molecular Cancer Therapeutics. PMID 28148714 DOI: 10.1182/Blood.V128.22.2525.2525  0.482
2017 Sanderson NS, Zimmermann M, Eilinger L, Gubser C, Schaeren-Wiemers N, Lindberg RL, Dougan SK, Ploegh HL, Kappos L, Derfuss T. Cocapture of cognate and bystander antigens can activate autoreactive B cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28057865 DOI: 10.1073/Pnas.1614472114  0.454
2016 Bilate AM, Bousbaine D, Mesin L, Agudelo M, Leube J, Kratzert A, Dougan SK, Victora GD, Ploegh HL. Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor. Science Immunology. 1: eaaf7471. PMID 28783695 DOI: 10.1126/Sciimmunol.Aaf7471  0.484
2016 Sanecka A, Yoshida N, Dougan SK, Jackson J, Shastri N, Ploegh H, Blanchard N, Frickel EM. Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute phase Toxoplasma gondii burden. Immunology. PMID 27377596 DOI: 10.1111/Imm.12643  0.453
2016 Dura B, Servos MM, Barry RM, Ploegh HL, Dougan SK, Voldman J. Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture. Proceedings of the National Academy of Sciences of the United States of America. PMID 27303033 DOI: 10.1073/Pnas.1515364113  0.38
2016 Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, et al. Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. PMID 26982724 DOI: 10.1038/Nature17421  0.433
2016 Tyler P, Servos M, Dougan SK. Abstract A067: Quality of initial activation of CD8 T cells specific for TRP1 determines long-term antitumor immunity Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A067  0.473
2016 Dougan M, Ingram J, Ploegh H, Dougan SK. Abstract B112: Targeting immunotherapy to the tumor microenvironment using anti-PDL1 VHH Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B112  0.374
2015 Tafesse FG, Rashidfarrokhi A, Schmidt FI, Freinkman E, Dougan S, Dougan M, Esteban A, Maruyama T, Strijbis K, Ploegh HL. Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans. Plos Pathogens. 11: e1005188. PMID 26431038 DOI: 10.1371/Journal.Ppat.1005188  0.399
2015 Santone M, Aprea S, Wu TY, Cooke MP, Mbow ML, Valiante NM, Rush JS, Dougan S, Avalos A, Ploegh H, De Gregorio E, Buonsanti C, D'Oro U. A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells. Human Vaccines & Immunotherapeutics. 0. PMID 26024409 DOI: 10.1080/21645515.2015.1027467  0.465
2015 Dura B, Dougan SK, Barisa M, Hoehl MM, Lo CT, Ploegh HL, Voldman J. Profiling lymphocyte interactions at the single-cell level by microfluidic cell pairing. Nature Communications. 6: 5940. PMID 25585172 DOI: 10.1038/Ncomms6940  0.415
2015 Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, et al. CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 517: 386-90. PMID 25363763 DOI: 10.1038/Nature13848  0.606
2015 Dougan SK, Bilate A, Jaenisch R, Ploegh HL. Abstract B59: Transnuclear mice as models of the immune response to pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B59  0.477
2014 Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS. Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. PMID 25367873 DOI: 10.1136/Gutjnl-2014-308541  0.43
2014 Shi J, Kundrat L, Pishesha N, Bilate A, Theile C, Maruyama T, Dougan SK, Ploegh HL, Lodish HF. Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. Proceedings of the National Academy of Sciences of the United States of America. 111: 10131-6. PMID 24982154 DOI: 10.1073/Pnas.1409861111  0.335
2014 Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V, Dougan SK, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, et al. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature. 506: 52-7. PMID 24476824 DOI: 10.1038/Nature12988  0.451
2013 Dougan SK, Dougan M, Kim J, Turner JA, Ogata S, Cho HI, Jaenisch R, Celis E, Ploegh HL. Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity. Cancer Immunology Research. 1: 99-111. PMID 24459675 DOI: 10.1158/2326-6066.Cir-13-0047  0.491
2013 Dougan SK, Ashour J, Karssemeijer RA, Popp MW, Avalos AM, Barisa M, Altenburg AF, Ingram JR, Cragnolini JJ, Guo C, Alt FW, Jaenisch R, Ploegh HL. Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus. Nature. 503: 406-9. PMID 24141948 DOI: 10.1038/Nature12637  0.345
2013 Fang M, Xie H, Dougan SK, Ploegh H, van Oudenaarden A. Stochastic cytokine expression induces mixed T helper cell States. Plos Biology. 11: e1001618. PMID 23935453 DOI: 10.1371/Journal.Pbio.1001618  0.415
2013 Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL. Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. Plos Pathogens. 9: e1003446. PMID 23825946 DOI: 10.1371/Journal.Ppat.1003446  0.322
2012 Dougan SK, Ogata S, Hu CC, Grotenbreg GM, Guillen E, Jaenisch R, Ploegh HL. IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 13739-44. PMID 22869725 DOI: 10.1073/Pnas.1210273109  0.38
2012 Dougan SK, Bilate A, Ploegh H. Abstract B75: Transnuclear mice from pancreatic tumor-infiltrating T cells. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B75  0.474
2011 Dougan SK, Hu CC, Paquet ME, Greenblatt MB, Kim J, Lilley BN, Watson N, Ploegh HL. Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes. Molecular and Cellular Biology. 31: 1145-59. PMID 21220515 DOI: 10.1128/Mcb.00967-10  0.368
2011 Zeissig S, Murata K, Hu Z, Kaser A, Dougan S, Bosse E, Scapa E, Cohen D, Arlt A, Franke A, Schreiber S, Liang T, Blumberg R. Hepatitis B-Virus-induzierte hepatozytäre Lipidantigene aktivieren Natürliche Killer T-Zellen und sind von zentraler Bedeutung für die antivirale Immunantwort Zeitschrift FüR Gastroenterologie. 49. DOI: 10.1055/S-0031-1285206  0.485
2011 Zeissig S, Murata K, Hu Z, Kaser A, Dougan SK, Bosse E, Scapa EF, Cohen DE, Arlt A, Franke A, Schreiber S, Liang TJ, Blumberg RS. Early Alterations in Endogenous Hepatocyte Lipid Antigens in Hepatitis B Virus Infection Are Associated With CD1D-Restricted Natural Killer T Cell Activation and Viral Clearance Gastroenterology. 140: S-886. DOI: 10.1016/S0016-5085(11)63685-8  0.54
2010 Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. The Journal of Experimental Medicine. 207: 2195-206. PMID 20837698 DOI: 10.1084/Jem.20101123  0.574
2010 Zeissig S, Dougan SK, Barral DC, Junker Y, Chen Z, Kaser A, Ho M, Mandel H, McIntyre A, Kennedy SM, Painter GF, Veerapen N, Besra GS, Cerundolo V, Yue S, et al. Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. The Journal of Clinical Investigation. 120: 2889-99. PMID 20592474 DOI: 10.1172/Jci42703  0.563
2009 Hu CC, Dougan SK, Winter SV, Paton AW, Paton JC, Ploegh HL. Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes. The Journal of Experimental Medicine. 206: 2429-40. PMID 19808260 DOI: 10.1084/Jem.20090782  0.369
2009 McGehee AM, Dougan SK, Klemm EJ, Shui G, Park B, Kim YM, Watson N, Wenk MR, Ploegh HL, Hu CC. XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis. Journal of Immunology (Baltimore, Md. : 1950). 183: 3690-9. PMID 19710472 DOI: 10.4049/Jimmunol.0900953  0.386
2009 Hu CC, Dougan SK, McGehee AM, Love JC, Ploegh HL. XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells. The Embo Journal. 28: 1624-36. PMID 19407814 DOI: 10.1038/Emboj.2009.117  0.399
2009 Zeissig S, Kaser A, Dougan SK, Scapa EF, Cohen DE, Blumberg RS. T1701 Microsomal Triglyceride Transfer Protein Regulates CD1D-Restricted Antigen Presentation of Hepatocytes and Controls NKT Cell Homeostasis via CD1D-Mediated Apoptosis Gastroenterology. 136: A-561. DOI: 10.1016/S0016-5085(09)62582-8  0.539
2009 Zeissig S, Dougan SK, Junker Y, Chen Z, Chen X, Kennedy S, Ho MM, Mandel H, Yue SC, Gumperz JE, Exley MA, Davidson NO, Blumberg RS. 706 Mutations in the Microsomal Triglyceride Transfer Protein Lead to a Defect in CD1D-Restricted Antigen Presentation and Impaired Activation of Natural Killer T Cells in Patients with Abetalipoproteinemia Gastroenterology. 136: A-111. DOI: 10.1016/S0016-5085(09)60501-1  0.553
2008 Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS. Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. European Journal of Immunology. 38: 2351-9. PMID 18624350 DOI: 10.1002/Eji.200738102  0.591
2008 Hussain MM, Rava P, Pan X, Dai K, Dougan SK, Iqbal J, Lazare F, Khatun I. Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism. Current Opinion in Lipidology. 19: 277-84. PMID 18460919 DOI: 10.1097/Mol.0B013E3282Feea85  0.31
2008 Zeissig S, Kaser A, Dougan S, Blumberg R. Das Microsomale Triglyzerid-Transferprotein (MTP) beeinflusst die CD1d-vermittelte Antigen-Präsentation von Hepatozyten und reguliert die periphere Natural Killer T (NKT)-Zell Homöostase Zeitschrift FüR Gastroenterologie. 46. DOI: 10.1055/S-0028-1089464  0.527
2008 Zeissig S, Kaser A, Dougan SK, Blumberg RS. T1241 Microsomal Triglyceride Transfer Protein Regulates CD1d-Restricted Antigen Presentation of Hepatocytes and Controls Natural Killer T Cell Homeostasis Via CD1d-Mediated Apoptosis Gastroenterology. 134: A-514. DOI: 10.1016/S0016-5085(08)62398-7  0.584
2007 Zeissig S, Kaser A, Dougan SK, Nieuwenhuis EE, Blumberg RS. Role of NKT cells in the digestive system. III. Role of NKT cells in intestinal immunity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 293: G1101-5. PMID 17717040 DOI: 10.1152/Ajpgi.00342.2007  0.587
2007 Dougan SK, Kaser A, Blumberg RS. CD1 expression on antigen-presenting cells. Current Topics in Microbiology and Immunology. 314: 113-41. PMID 17593659 DOI: 10.1007/978-3-540-69511-0_5  0.539
2007 Dougan SK, Rava P, Hussain MM, Blumberg RS. MTP regulated by an alternate promoter is essential for NKT cell development. The Journal of Experimental Medicine. 204: 533-45. PMID 17312007 DOI: 10.1084/Jem.20062006  0.598
2005 Dougan SK, Salas A, Rava P, Agyemang A, Kaser A, Morrison J, Khurana A, Kronenberg M, Johnson C, Exley M, Hussain MM, Blumberg RS. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. The Journal of Experimental Medicine. 202: 529-39. PMID 16087713 DOI: 10.1084/Jem.20050183  0.559
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