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Brian Bierie, Ph.D. - Publications

Affiliations: 
2008 Vanderbilt University, Nashville, TN 
Area:
Molecular Biology
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lambert AW, Fiore C, Chutake Y, Verhaar ER, Strasser PC, Chen MW, Farouq D, Das S, Li X, Eaton EN, Zhang Y, Liu Donaher J, Engstrom I, Reinhardt F, Yuan B, ... ... Bierie B, et al. ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells. Developmental Cell. 57: 2714-2730.e8. PMID 36538894 DOI: 10.1016/j.devcel.2022.11.015  0.312
2020 Kurley SJ, Tischler V, Bierie B, Novitskiy SV, Noske A, Varga Z, Zürrer-Härdi U, Brandt S, Carnahan RH, Cook RS, Muller WJ, Richmond A, Reynolds AB. A Requirement for p120-catenin in the metastasis of invasive ductal breast cancer. Journal of Cell Science. PMID 33097605 DOI: 10.1242/jcs.250639  0.331
2020 Lambert A, Fiore C, Chutake Y, Verhaar E, Chen MW, Donaher J, Reinhardt F, Engstrom I, Yuan B, Bierie B, Farouq D, Carulli J, Olson E, Guenther M, Weinberg R. Abstract P4-04-02: Epigenomic analysis of cancer stem cells (CSCs) from triple-negative breast cancer (TNBC) reveals p63 and p73 as core metastasis drivers Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-04-02  0.379
2019 Kröger C, Afeyan A, Mraz J, Eaton EN, Reinhardt F, Khodor YL, Thiru P, Bierie B, Ye X, Burge CB, Weinberg RA. Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30910979 DOI: 10.1073/Pnas.1812876116  0.359
2018 van Dijk D, Sharma R, Nainys J, Yim K, Kathail P, Carr AJ, Burdziak C, Moon KR, Chaffer CL, Pattabiraman D, Bierie B, Mazutis L, Wolf G, Krishnaswamy S, Pe'er D. Recovering Gene Interactions from Single-Cell Data Using Data Diffusion. Cell. PMID 29961576 DOI: 10.1016/J.Cell.2018.05.061  0.315
2018 Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA. The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy. Science Translational Medicine. 10. PMID 29643230 DOI: 10.1126/Scitranslmed.Aan3464  0.407
2018 Guenther M, Lambert A, Chen M, Fiore C, Eaton M, Orlando D, Bierie B, Weinberg R, Fritz C, Olson E. Abstract P2-04-03: Epigenomic analysis of cancer stem cell (CSC)-enriched triple-negative breast cancer (TNBC) populations reveals gene regulatory circuitry and novel tumor cell vulnerabilities Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P2-04-03  0.458
2017 Rashidian M, Ingram JR, Dougan M, Dongre A, Whang KA, LeGall C, Cragnolini JJ, Bierie B, Gostissa M, Gorman J, Grotenbreg GM, Bhan A, Weinberg RA, Ploegh HL. Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells. The Journal of Experimental Medicine. PMID 28666979 DOI: 10.1084/Jem.20161950  0.35
2017 Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. PMID 28329758 DOI: 10.1038/Nature21408  0.344
2017 Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova Z, Weinberg RA. Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270621 DOI: 10.1073/Pnas.1618298114  0.478
2016 Wang H, Bierie B, Li AG, Pathania S, Toomire K, Dimitrov SD, Liu B, Gelman R, Giobbie-Hurder A, Feunteun J, Polyak K, Livingston DM. BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells. Molecular Cell. PMID 27373334 DOI: 10.1016/J.Molcel.2016.05.038  0.348
2016 Pattabiraman DR, Bierie B, Kober KI, Thiru P, Krall JA, Zill C, Reinhardt F, Tam WL, Weinberg RA. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science (New York, N.Y.). 351: aad3680. PMID 26941323 DOI: 10.1126/Science.Aad3680  0.465
2014 Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, et al. Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 158: 1094-109. PMID 25171410 DOI: 10.1016/J.Cell.2014.07.032  0.403
2013 Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA. Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell. 24: 347-64. PMID 24029232 DOI: 10.1016/J.Ccr.2013.08.005  0.388
2013 Pattabiraman DR, Reinhardt F, Bierie B, Weinberg RA. Abstract 1497: Inducing a mesenchymal-to-epithelial transition for the targeting of cancer stem cells. Cancer Research. 73: 1497-1497. DOI: 10.1158/1538-7445.Am2013-1497  0.441
2012 Kurley SJ, Bierie B, Carnahan RH, Lobdell NA, Davis MA, Hofmann I, Moses HL, Muller WJ, Reynolds AB. p120-catenin is essential for terminal end bud function and mammary morphogenesis. Development (Cambridge, England). 139: 1754-64. PMID 22461563 DOI: 10.1242/Dev.072769  0.517
2011 Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, et al. Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. The Journal of Clinical Investigation. 121: 4106-17. PMID 21926469 DOI: 10.1172/Jci42754  0.623
2011 Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proceedings of the National Academy of Sciences of the United States of America. 108: 7950-5. PMID 21498687 DOI: 10.1073/Pnas.1102454108  0.362
2010 Bierie B, Moses HL. Transforming growth factor beta (TGF-beta) and inflammation in cancer. Cytokine & Growth Factor Reviews. 21: 49-59. PMID 20018551 DOI: 10.1016/J.Cytogfr.2009.11.008  0.728
2009 Bierie B, Moses HL. Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis. Cell Cycle (Georgetown, Tex.). 8: 3319-27. PMID 19806012 DOI: 10.4161/Cc.8.20.9727  0.655
2009 Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, Aakre M, Shyr Y, Moses HL. Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. The Journal of Clinical Investigation. 119: 1571-82. PMID 19451693 DOI: 10.1172/Jci37480  0.703
2009 Abel TW, Clark C, Bierie B, Chytil A, Aakre M, Gorska A, Moses HL. GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma. Molecular Cancer Research : McR. 7: 645-53. PMID 19435821 DOI: 10.1158/1541-7786.Mcr-08-0477  0.581
2009 Bierie B, Gorska AE, Stover DG, Moses HL. TGF-beta promotes cell death and suppresses lactation during the second stage of mammary involution. Journal of Cellular Physiology. 219: 57-68. PMID 19086032 DOI: 10.1002/Jcp.21646  0.69
2009 Yu X, Wang Y, Jiang M, Bierie B, Roy-Burman P, Shen MM, Taketo MM, Wills M, Matusik RJ. Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration. The Prostate. 69: 249-62. PMID 18991257 DOI: 10.1002/Pros.20877  0.501
2008 Bierie B, Stover DG, Abel TW, Chytil A, Gorska AE, Aakre M, Forrester E, Yang L, Wagner KU, Moses HL. Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Cancer Research. 68: 1809-19. PMID 18339861 DOI: 10.1158/0008-5472.Can-07-5597  0.756
2008 Bierie B, Moses HL. 30 TGF-β and the Tumor Microenvironment Cold Spring Harbor Monograph Archive. 50: 965-987. DOI: 10.1101/087969752.50.965  0.587
2007 Stover DG, Bierie B, Moses HL. A delicate balance: TGF-beta and the tumor microenvironment. Journal of Cellular Biochemistry. 101: 851-61. PMID 17486574 DOI: 10.1002/Jcb.21149  0.749
2006 Bierie B, Moses HL. Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nature Reviews. Cancer. 6: 506-20. PMID 16794634 DOI: 10.1038/Nrc1926  0.601
2006 Bierie B, Moses HL. TGF-beta and cancer. Cytokine & Growth Factor Reviews. 17: 29-40. PMID 16289860 DOI: 10.1016/J.Cytogfr.2005.09.006  0.723
2005 Bierie B, Moses HL. Under pressure: stromal fibroblasts change their ways. Cell. 123: 985-7. PMID 16360028 DOI: 10.1016/J.Cell.2005.11.029  0.608
2005 Xie L, Xu BJ, Gorska AE, Shyr Y, Schwartz SA, Cheng N, Levy S, Bierie B, Caprioli RM, Moses HL. Genomic and proteomic analysis of mammary tumors arising in transgenic mice. Journal of Proteome Research. 4: 2088-98. PMID 16335954 DOI: 10.1021/Pr050214L  0.707
2005 Le Provost F, Miyoshi K, Vilotte JL, Bierie B, Robinson GW, Hennighausen L. SOCS3 promotes apoptosis of mammary differentiated cells. Biochemical and Biophysical Research Communications. 338: 1696-701. PMID 16289036 DOI: 10.1016/J.Bbrc.2005.10.138  0.428
2005 Thangaraju M, Rudelius M, Bierie B, Raffeld M, Sharan S, Hennighausen L, Huang AM, Sterneck E. C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution. Development (Cambridge, England). 132: 4675-85. PMID 16192306 DOI: 10.1242/Dev.02050  0.335
2005 Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL. Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. Cancer Research. 65: 2296-302. PMID 15781643 DOI: 10.1158/0008-5472.Can-04-3272  0.756
2004 Bierie B, Edwin M, Melenhorst JJ, Hennighausen L. The proliferation associated nuclear element (PANE1) is conserved between mammals and fish and preferentially expressed in activated lymphoid cells. Gene Expression Patterns : Gep. 4: 389-95. PMID 15183305 DOI: 10.1016/J.Modgep.2004.01.008  0.483
2004 Nemade RV, Bierie B, Nozawa M, Bry C, Smith GH, Vasioukhin V, Fuchs E, Hennighausen L. Biogenesis and function of mouse mammary epithelium depends on the presence of functional alpha-catenin. Mechanisms of Development. 121: 91-9. PMID 14706703 DOI: 10.1016/J.Mod.2003.09.007  0.352
2003 Gallego MI, Bierie B, Hennighausen L. Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways. Oncogene. 22: 8498-508. PMID 14627990 DOI: 10.1038/Sj.Onc.1207063  0.463
2003 Renou JP, Bierie B, Miyoshi K, Cui Y, Djiane J, Reichenstein M, Shani M, Hennighausen L. Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated β-catenin Oncogene. 22: 4594-4610. PMID 12881717 DOI: 10.1038/Sj.Onc.1206596  0.395
2003 Bierie B, Nozawa M, Renou JP, Shillingford JM, Morgan F, Oka T, Taketo MM, Cardiff RD, Miyoshi K, Wagner KU, Robinson GW, Hennighausen L. Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation. Oncogene. 22: 3875-87. PMID 12813461 DOI: 10.1038/Sj.Onc.1206426  0.426
2002 Humphreys RC, Bierie B, Zhao L, Raz R, Levy D, Hennighausen L. Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli. Endocrinology. 143: 3641-50. PMID 12193580 DOI: 10.1210/En.2002-220224  0.316
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