| Year |
Citation |
Score |
| 2024 |
Yu J, Yan C, Paul T, Brewer L, Tsutakawa SE, Tsai CL, Hamdan SM, Tainer JA, Ivanov I. Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nature Communications. 15: 8511. PMID 39353945 DOI: 10.1038/s41467-024-52860-y |
0.685 |
|
| 2024 |
Longo MA, Ahmed SM, Chen Y, Tsai CL, Namjoshi S, Wang X, Perera RL, Arvai A, Lee M, Kong LR, Engl W, Shyuan W, Zhao ZW, Venkitaraman AR, Tainer JA, et al. BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability. Biorxiv : the Preprint Server For Biology. PMID 39345573 DOI: 10.1101/2024.09.21.614229 |
0.435 |
|
| 2024 |
Pradhan S, Bush K, Zhang N, Pandita RK, Tsai CL, Smith C, Pandlebury DF, Gaikwad S, Leonard F, Nie L, Tao A, Russell W, Yuan S, Choudhary S, Ramos KS, ... ... Tainer JA, et al. Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons. Biorxiv : the Preprint Server For Biology. PMID 39345557 DOI: 10.1101/2024.09.19.613927 |
0.318 |
|
| 2024 |
De-Paula RB, Bacolla A, Syed A, Tainer JA. Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation. The Journal of Biological Chemistry. 107822. PMID 39341500 DOI: 10.1016/j.jbc.2024.107822 |
0.551 |
|
| 2024 |
Provasek VE, Bacolla A, Rangaswamy S, Mitra J, Kodavati M, Yusuf IO, Malojirao VH, Vasquez V, Britz GW, Li GM, Xu Z, Mitra S, Garruto RM, Tainer JA, Hegde ML. RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability. Biorxiv : the Preprint Server For Biology. PMID 38798341 DOI: 10.1101/2024.05.16.594552 |
0.32 |
|
| 2024 |
Chinnam NB, Thapar R, Arvai AS, Sarker AH, Soll JM, Paul T, Syed A, Rosenberg DJ, Hammel M, Bacolla A, Katsonis P, Asthana A, Tsai MS, Ivanov I, Lichtarge O, ... ... Tainer JA, et al. ASCC1 structures and bioinformatics reveal a novel Helix-Clasp-Helix RNA-binding motif linked to a two-histidine phosphodiesterase. The Journal of Biological Chemistry. 107368. PMID 38750793 DOI: 10.1016/j.jbc.2024.107368 |
0.759 |
|
| 2024 |
Filandr F, Sarpe V, Raval S, Crowder DA, Khan MF, Douglas P, Coales S, Viner R, Syed A, Tainer JA, Lees-Miller SP, Schriemer DC. Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology. Nature Communications. 15: 2836. PMID 38565885 DOI: 10.1038/s41467-024-47157-z |
0.492 |
|
| 2024 |
Filandr F, Sarpe V, Raval S, Crowder DA, Khan MF, Douglas P, Coales S, Viner R, Syed A, Tainer JA, Lees-Miller SP, Schriemer DC. Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology. Nature Communications. 15: 2200. PMID 38467655 DOI: 10.1038/s41467-024-46610-3 |
0.541 |
|
| 2024 |
Woltz R, Schweibenz B, Tsutakawa SE, Zhao C, Ma L, Shurina B, Hura GL, John R, Vorobiev S, Swapna G, Solotchi M, Tainer JA, Krug RM, Patel SS, Montelione GT. The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral response. Biorxiv : the Preprint Server For Biology. PMID 38328244 DOI: 10.1101/2023.09.25.559316 |
0.614 |
|
| 2023 |
Swift ML, Zhou R, Syed A, Moreau LA, Tomasik B, Tainer JA, Konstantinopoulos PA, D'Andrea AD, He YJ, Chowdhury D. Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs. Nature Structural & Molecular Biology. PMID 37696958 DOI: 10.1038/s41594-023-01074-9 |
0.67 |
|
| 2023 |
Syed A, Filandr F, Patterson-Fortin J, Bacolla A, Ravindranathan R, Zhou J, McDonald DT, Albuhluli ME, Verway-Cohen A, Newman JA, Tsai MS, Jones DE, Schriemer DC, D'Andrea AD, Tainer JA. Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity. Nucleic Acids Research. PMID 37665033 DOI: 10.1093/nar/gkad727 |
0.635 |
|
| 2023 |
Longo MA, Roy S, Chen Y, Tomaszowski KH, Arvai AS, Pepper JT, Boisvert RA, Kunnimalaiyaan S, Keshvani C, Schild D, Bacolla A, Williams GJ, Tainer JA, Schlacher K. RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. Nature Communications. 14: 4445. PMID 37488098 DOI: 10.1038/s41467-023-40096-1 |
0.314 |
|
| 2023 |
Yu J, Yan C, Dodd T, Tsai CL, Tainer JA, Tsutakawa SE, Ivanov I. Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases. Nature Communications. 14: 2758. PMID 37179334 DOI: 10.1038/s41467-023-38416-6 |
0.669 |
|
| 2023 |
Zhou R, Swift ML, Syed A, Huang K, Moreau L, Tainer JA, Konstantinopoulos PA, Dâ Andrea AD, He YJ, Chowdhury D. Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs. Biorxiv : the Preprint Server For Biology. PMID 37034578 DOI: 10.1101/2023.03.27.534416 |
0.667 |
|
| 2023 |
LeBleu VS, Dai J, Tsutakawa S, MacDonald BA, Alge JL, Sund M, Xie L, Sugimoto H, Tainer J, Zon LI, Kalluri R. Identification of unique α4 chain structure and conserved antiangiogenic activity of α3NC1 type IV collagen in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 37002899 DOI: 10.1002/dvdy.590 |
0.565 |
|
| 2022 |
Chinnam NB, Syed A, Hura GL, Hammel M, Tainer JA, Tsutakawa SE. Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution. Methods in Enzymology. 678: 351-376. PMID 36641214 DOI: 10.1016/bs.mie.2022.09.023 |
0.731 |
|
| 2022 |
Bralić A, Tehseen M, Sobhy MA, Tsai CL, Alhudhali L, Yi G, Yu J, Yan C, Ivanov I, Tsutakawa SE, Tainer JA, Hamdan SM. A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair. Nucleic Acids Research. PMID 36477609 DOI: 10.1093/nar/gkac1095 |
0.706 |
|
| 2022 |
Fan C, Chen K, Wang Y, Ball EV, Stenson PD, Mort M, Bacolla A, Kehrer-Sawatzki H, Tainer JA, Cooper DN, Zhao H. Profiling human pathogenic repeat expansion regions by synergistic and multi-level impacts on molecular connections. Human Genetics. PMID 36344696 DOI: 10.1007/s00439-022-02500-6 |
0.334 |
|
| 2022 |
Kim M, Kim HS, D'Souza A, Gallagher K, Jeong E, Topolska-Wós A, Ogorodnik Le Meur K, Tsai CL, Tsai MS, Kee M, Tainer JA, Yeo JE, Chazin WJ, Schärer OD. Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207408119. PMID 35969784 DOI: 10.1073/pnas.2207408119 |
0.377 |
|
| 2022 |
Rosenberg DJ, Syed A, Tainer JA, Hura GL. Monitoring Nuclease Activity by X-Ray Scattering Interferometry Using Gold Nanoparticle-Conjugated DNA. Methods in Molecular Biology (Clifton, N.J.). 2444: 183-205. PMID 35290639 DOI: 10.1007/978-1-0716-2063-2_12 |
0.666 |
|
| 2022 |
Chinnam NB, Syed A, Burnett KH, Hura GL, Tainer JA, Tsutakawa SE. Universally Accessible Structural Data on Macromolecular Conformation, Assembly, and Dynamics by Small Angle X-Ray Scattering for DNA Repair Insights. Methods in Molecular Biology (Clifton, N.J.). 2444: 43-68. PMID 35290631 DOI: 10.1007/978-1-0716-2063-2_4 |
0.796 |
|
| 2021 |
Tsutakawa SE, Bacolla A, Katsonis P, Bralić A, Hamdan SM, Lichtarge O, Tainer JA, Tsai CL. Decoding Cancer Variants of Unknown Significance for Helicase-Nuclease-RPA Complexes Orchestrating DNA Repair During Transcription and Replication. Frontiers in Molecular Biosciences. 8: 791792. PMID 34966786 DOI: 10.3389/fmolb.2021.791792 |
0.645 |
|
| 2021 |
Twayana S, Bacolla A, Barreto-Galvez A, De-Paula RB, Drosopoulos WC, Kosiyatrakul ST, Bouhassira EE, Tainer JA, Madireddy A, Schildkraut CL. Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34815340 DOI: 10.1073/pnas.2106477118 |
0.334 |
|
| 2021 |
Moiani D, Link TM, Brosey CA, Katsonis P, Lichtarge O, Kim Y, Joachimiak A, Ma Z, Kim IK, Ahmed Z, Jones DE, Tsutakawa SE, Tainer JA. An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2. Methods in Enzymology. 661: 407-431. PMID 34776222 DOI: 10.1016/bs.mie.2021.09.003 |
0.628 |
|
| 2021 |
Alexander LT, Lepore R, Kryshtafovych A, Adamopoulos A, Alahuhta M, Arvin AM, Bomble YJ, Böttcher B, Breyton C, Chiarini V, Chinnam NB, Chiu W, Fidelis K, Grinter R, Gupta GD, ... ... Tainer JA, et al. Target highlights in CASP14: analysis of models by structure providers. Proteins. PMID 34561912 DOI: 10.1002/prot.26247 |
0.604 |
|
| 2021 |
Ye Z, Xu S, Shi Y, Bacolla A, Syed A, Moiani D, Tsai CL, Shen Q, Peng G, Leonard PG, Jones DE, Wang B, Tainer JA, Ahmed Z. GRB2 enforces homology-directed repair initiation by MRE11. Science Advances. 7. PMID 34348893 DOI: 10.1126/sciadv.abe9254 |
0.621 |
|
| 2021 |
Hambarde S, Tsai CL, Pandita RK, Bacolla A, Maitra A, Charaka V, Hunt CR, Kumar R, Limbo O, Le Meur R, Chazin WJ, Tsutakawa SE, Russell P, Schlacher K, Pandita TK, ... Tainer JA, et al. EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Molecular Cell. PMID 34197737 DOI: 10.1016/j.molcel.2021.05.027 |
0.726 |
|
| 2021 |
Rashid I, Hammel M, Sverzhinsky A, Tsai MS, Pascal JM, Tainer JA, Tomkinson AE. Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus. The Journal of Biological Chemistry. 100921. PMID 34181949 DOI: 10.1016/j.jbc.2021.100921 |
0.437 |
|
| 2021 |
Zhou J, Gelot C, Pantelidou C, Li A, Yücel H, Davis RE, Farkkila A, Kochupurakkal B, Syed A, Shapiro GI, Tainer JA, Blagg BSJ, Ceccaldi R, D'Andrea AD. A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors. Nature Cancer. 2: 598-610. PMID 34179826 DOI: 10.1038/s43018-021-00203-x |
0.585 |
|
| 2021 |
Hammel M, Tainer JA. X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology. Protein Science : a Publication of the Protein Society. PMID 34056803 DOI: 10.1002/pro.4133 |
0.424 |
|
| 2021 |
Banday S, Pandita RK, Mushtaq A, Bacolla A, Mir US, Singh DK, Jan S, Bhat KP, Hunt CR, Rao G, Charaka VK, Tainer JA, Pandita TK, Altaf M. Autism-associated vigilin depletion impairs DNA damage repair. Molecular and Cellular Biology. PMID 33941620 DOI: 10.1128/MCB.00082-21 |
0.373 |
|
| 2021 |
Zhang X, Blundell T, Tainer JA. The renaissance in biophysics and molecular biology enabled by the interface of DNA repair and replication with cancer. Progress in Biophysics and Molecular Biology. PMID 33798567 DOI: 10.1016/j.pbiomolbio.2021.03.006 |
0.307 |
|
| 2021 |
Nguyen MT, Moiani D, Ahmed Z, Arvai AS, Namjoshi S, Shin DS, Fedorov Y, Selvik EJ, Jones DE, Pink J, Yan Y, Laverty DJ, Nagel ZD, Tainer JA, Gerson SL. An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Progress in Biophysics and Molecular Biology. PMID 33675849 DOI: 10.1016/j.pbiomolbio.2021.02.004 |
0.391 |
|
| 2020 |
Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. Nucleic Acids Research. PMID 33330937 DOI: 10.1093/nar/gkaa1188 |
0.423 |
|
| 2020 |
Bacolla A, Sengupta S, Ye Z, Yang C, Mitra J, De-Paula RB, Hegde ML, Ahmed Z, Mort M, Cooper DN, Mitra S, Tainer JA. Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin. Nucleic Acids Research. PMID 33300026 DOI: 10.1093/nar/gkaa1120 |
0.324 |
|
| 2020 |
Wilson DM, Deacon AM, Duncton MAJ, Pellicena P, Georgiadis MM, Yeh AP, Arvai AS, Moiani D, Tainer JA, Das D. Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response. Progress in Biophysics and Molecular Biology. PMID 33115610 DOI: 10.1016/j.pbiomolbio.2020.10.005 |
0.304 |
|
| 2020 |
Thapar R, Wang JL, Hammel M, Ye R, Liang K, Sun C, Hnizda A, Liang S, Maw SS, Lee L, Villarreal H, Forrester I, Fang S, Tsai MS, Blundell TL, ... ... Tainer JA, et al. Mechanism of efficient double-strand break repair by a long non-coding RNA. Nucleic Acids Research. PMID 33045735 DOI: 10.1093/nar/gkaa784 |
0.346 |
|
| 2020 |
Lees-Miller JP, Cobban A, Katsonis P, Bacolla A, Tsutakawa SE, Hammel M, Meek K, Anderson DW, Lichtarge O, Tainer JA, Lees-Miller SP. Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease. Progress in Biophysics and Molecular Biology. PMID 33035590 DOI: 10.1016/j.pbiomolbio.2020.09.010 |
0.72 |
|
| 2020 |
Tsutakawa SE, Tsai CL, Yan C, Bralić A, Chazin WJ, Hamdan SM, Schärer OD, Ivanov I, Tainer JA. Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair. Dna Repair. 96: 102972. PMID 33007515 DOI: 10.1016/J.Dnarep.2020.102972 |
0.711 |
|
| 2020 |
Hammel M, Rosenberg DJ, Bierma J, Hura GL, Lees-Miller SP, Tainer JA. Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM. Progress in Biophysics and Molecular Biology. PMID 32966823 DOI: 10.1016/J.Pbiomolbio.2020.09.003 |
0.435 |
|
| 2020 |
Tsutakawa SE, Sarker AH, Ng C, Arvai AS, Shin DS, Shih B, Jiang S, Thwin AC, Tsai MS, Willcox A, Her MZ, Trego KS, Raetz AG, Rosenberg D, Bacolla A, ... ... Tainer JA, et al. Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 32522879 DOI: 10.1073/Pnas.1921311117 |
0.78 |
|
| 2019 |
Hura GL, Hodge CD, Rosenberg D, Guzenko D, Duarte JM, Monastyrskyy B, Grudinin S, Kryshtafovych A, Tainer JA, Fidelis K, Tsutakawa SE. Small angle X-ray scattering-assisted protein structure prediction in CASP13 and emergence of solution structure differences. Proteins. PMID 31589784 DOI: 10.1002/Prot.25827 |
0.614 |
|
| 2019 |
Zhang H, Chen Z, Ye Y, Ye Z, Cao D, Xiong Y, Srivastava M, Feng X, Tang M, Wang C, Tainer JA, Chen J. SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair. Nucleic Acids Research. PMID 31495888 DOI: 10.1093/nar/gkz769 |
0.367 |
|
| 2019 |
Yan C, Dodd T, He Y, Tainer JA, Tsutakawa SE, Ivanov I. Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nature Structural & Molecular Biology. PMID 31110295 DOI: 10.1038/s41594-019-0220-3 |
0.694 |
|
| 2019 |
Syed A, Tainer JA. Charge Transport Communication through DNA by Protein Fe-S Clusters: How Far Is Not Too Far? Acs Central Science. 5: 7-9. PMID 30693320 DOI: 10.1021/Acscentsci.8B00909 |
0.616 |
|
| 2018 |
Tang HYH, Shin DS, Hura GL, Yang Y, Hu X, Lightstone FC, McGee MD, Padgett HS, Yannone SM, Tainer JA. Structural control of nonnative ligand binding in engineered mutants of phosphoenolpyruvate carboxykinase. Biochemistry. PMID 30376300 DOI: 10.1021/Acs.Biochem.8B00963 |
0.547 |
|
| 2018 |
Wang JL, Duboc C, Wu Q, Ochi T, Liang S, Tsutakawa SE, Lees-Miller SP, Nadal M, Tainer JA, Blundell TL, Strick TR. Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature Structural & Molecular Biology. PMID 29786079 DOI: 10.1038/S41594-018-0065-1 |
0.719 |
|
| 2018 |
Syed A, Tainer JA. The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair. Annual Review of Biochemistry. PMID 29709199 DOI: 10.1146/Annurev-Biochem-062917-012415 |
0.67 |
|
| 2018 |
Moiani D, Ronato DA, Brosey CA, Arvai AS, Syed A, Masson JY, Petricci E, Tainer JA. Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities. Methods in Enzymology. 601: 205-241. PMID 29523233 DOI: 10.1016/Bs.Mie.2017.11.030 |
0.628 |
|
| 2018 |
Ogorzalek TL, Hura GL, Belsom A, Burnett KH, Kryshtafovych A, Tainer JA, Rappsilber J, Tsutakawa SE, Fidelis K. Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy. Proteins. PMID 29314274 DOI: 10.1002/Prot.25452 |
0.602 |
|
| 2018 |
Ogorzalek TL, Hura GL, Kryshtafovych A, Tainer JA, Fidelis K, Tsutakawa SE. Small Angle X-ray Scattering for Data-Assisted Structure Prediction in CASP12 with Prospects to Improve Accuracy Biophysical Journal. 114: 576a-577a. DOI: 10.1016/J.Bpj.2017.11.3152 |
0.577 |
|
| 2017 |
Tsutakawa SE, Thompson MJ, Arvai AS, Neil AJ, Shaw SJ, Algasaier SI, Kim JC, Finger LD, Jardine E, Gotham VJB, Sarker AH, Her MZ, Rashid F, Hamdan SM, Mirkin SM, ... ... Tainer JA, et al. Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nature Communications. 8: 16145. PMID 31305777 DOI: 10.1038/ncomms16145 |
0.572 |
|
| 2017 |
Brosey CA, Ahmed Z, Lees-Miller SP, Tainer JA. What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses. Methods in Enzymology. 592: 417-455. PMID 28668129 DOI: 10.1016/Bs.Mie.2017.04.005 |
0.375 |
|
| 2017 |
Tsutakawa SE, Thompson MJ, Arvai AS, Neil AJ, Shaw SJ, Algasaier SI, Kim JC, Finger LD, Jardine E, Gotham VJB, Sarker AH, Her MZ, Rashid F, Hamdan SM, Mirkin SM, ... ... Tainer JA, et al. Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nature Communications. 8: 15855. PMID 28653660 DOI: 10.1038/Ncomms15855 |
0.702 |
|
| 2017 |
Aceytuno RD, Piett CG, Havali-Shahriari Z, Edwards RA, Rey M, Ye R, Javed F, Fang S, Mani R, Weinfeld M, Hammel M, Tainer JA, Schriemer DC, Lees-Miller SP, Glover JNM. Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex. Nucleic Acids Research. PMID 28453785 DOI: 10.1093/Nar/Gkx275 |
0.426 |
|
| 2017 |
Rashid F, Harris PD, Zaher MS, Sobhy MA, Joudeh LI, Yan C, Piwonski H, Tsutakawa SE, Ivanov I, Tainer JA, Habuchi S, Hamdan SM. Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1. Elife. 6. PMID 28230529 DOI: 10.7554/Elife.21884 |
0.73 |
|
| 2017 |
Wallen JR, Zhang H, Weis C, Cui W, Foster BM, Ho CM, Hammel M, Tainer JA, Gross ML, Ellenberger T. Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome. Structure (London, England : 1993). 25: 157-166. PMID 28052235 DOI: 10.1016/J.Str.2016.11.019 |
0.438 |
|
| 2017 |
Tang HYH, Hura GL, Shin DS, Yannone SM, Tainer JA. Effects of engineering non-native ligand binding into E. coli phosphoenolpyruvate carboxykinase Acta Crystallographica Section a Foundations and Advances. 73: a207-a207. DOI: 10.1107/S0108767317097963 |
0.483 |
|
| 2017 |
Tainer JA, Tsutakawa SE, Hura GL, Hammel M. Super resolution for X-ray scattering and biological insights from its applications to dynamic DNA replication and repair complexes Acta Crystallographica Section a Foundations and Advances. 73: a314-a314. DOI: 10.1107/S0108767317096921 |
0.654 |
|
| 2017 |
Aceytuno D, Piett C, Havali-Shahriari Z, Edwards R, Rey M, Mani R, Fang S, Hammel M, Weinfeld M, Tainer J, Schriemer D, Lees-Miller S, Glover J. Clinical dysregulation of DNA repair by the polynucleotide kinase/phosphatase-XRCC4-DNA ligase IV in neurological disease Annals of Oncology. 28: v17. DOI: 10.1093/Annonc/Mdx361.058 |
0.324 |
|
| 2016 |
Hammel M, Yu Y, Radhakrishnan SK, Chokshi C, Tsai MS, Matsumoto Y, Kuzdovich M, Remesh SG, Fang S, Tomkinson AE, Lees-Miller SP, Tainer JA. An Intrinsically Disordered APLF Links Ku, DNA-PKcs and XRCC4-DNA Ligase IV in an Extended Flexible Non-Homologous End Joining Complex. The Journal of Biological Chemistry. PMID 27875301 DOI: 10.1074/Jbc.M116.751867 |
0.392 |
|
| 2016 |
Stingele J, Bellelli R, Alte F, Hewitt G, Sarek G, Maslen SL, Tsutakawa SE, Borg A, Kjær S, Tainer JA, Skehel JM, Groll M, Boulton SJ. Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Molecular Cell. 64: 688-703. PMID 27871365 DOI: 10.1016/J.Molcel.2016.09.031 |
0.717 |
|
| 2016 |
Hammel M, Amlanjyoti D, Reyes FE, Chen JH, Parpana R, Tang HY, Larabell CA, Tainer JA, Adhya S. HU multimerization shift controls nucleoid compaction. Science Advances. 2: e1600650. PMID 27482541 DOI: 10.1107/S0108767317099019 |
0.377 |
|
| 2016 |
Bacolla A, Tainer JA, Vasquez KM, Cooper DN. Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences. Nucleic Acids Research. PMID 27084947 DOI: 10.1093/Nar/Gkw261 |
0.306 |
|
| 2016 |
Deshpande RA, Williams GJ, Limbo O, Williams RS, Kuhnlein J, Lee JH, Classen S, Guenther G, Russell P, Tainer JA, Paull TT. ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. The Embo Journal. 35: 791. PMID 27037288 DOI: 10.15252/Embj.201694047 |
0.303 |
|
| 2016 |
Youngblut MD, Tsai CL, Clark IC, Carlson HK, Maglaqui AP, Gau-Pan PS, Redford SA, Wong A, Tainer JA, Coates JD. Perchlorate Reductase is Distinguished by Active Site Aromatic Gate Residues. The Journal of Biological Chemistry. PMID 26940877 DOI: 10.1074/Jbc.M116.714618 |
0.309 |
|
| 2015 |
Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Exploring the repeat protein universe through computational protein design. Nature. PMID 26675729 DOI: 10.1038/Nature16162 |
0.631 |
|
| 2015 |
Shin DS, Tainer JA. Molecular biology: DNA repair without flipping out. Nature. PMID 26524524 DOI: 10.1038/Nature15646 |
0.652 |
|
| 2015 |
Pratt AJ, DiDonato M, Shin DS, Cabelli DE, Bruns CK, Belzer CA, Gorringe AR, Langford PR, Tabatabai LB, Kroll JS, Tainer JA, Getzoff ED. Structural, functional and immunogenic insights on Cu,Zn Superoxide Dismutase pathogenic virulence factors from Neisseria meningitidis and Brucella abortus. Journal of Bacteriology. PMID 26459556 DOI: 10.1128/Jb.00343-15 |
0.671 |
|
| 2015 |
Tsai CL, Williams GJ, Perry JJ, Tainer JA. An AAA+ ATPase Clamshell Targets Transposition. Cell. 162: 701-3. PMID 26276624 DOI: 10.1016/j.cell.2015.07.050 |
0.378 |
|
| 2015 |
Kukshal V, Kim IK, Hura GL, Tomkinson AE, Tainer JA, Ellenberger T. Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining. Nucleic Acids Research. 43: 7021-31. PMID 26130724 DOI: 10.1093/Nar/Gkv652 |
0.418 |
|
| 2015 |
Tsutakawa SE, Yan C, Xu X, Zhuang Z, Todd Washington M, Tainer JA, Ivanov I. 112 Structurally distinct ubiquitin- and SUMO-modified PCNA: implications for their distinct roles in the DNA damage response. Journal of Biomolecular Structure & Dynamics. 33: 70-1. PMID 26103323 DOI: 10.1080/07391102.2015.1032745 |
0.715 |
|
| 2015 |
Tsutakawa SE, Tainer JA. Bending Forks and Wagging Dogs--It's about the DNA 3' Tail. Molecular Cell. 58: 972-3. PMID 26091346 DOI: 10.1016/J.Molcel.2015.06.005 |
0.688 |
|
| 2015 |
Tsutakawa SE, Yan C, Xu X, Weinacht CP, Freudenthal BD, Yang K, Zhuang Z, Washington MT, Tainer JA, Ivanov I. Structurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response. Structure (London, England : 1993). 23: 724-33. PMID 25773143 DOI: 10.1016/J.Str.2015.02.008 |
0.715 |
|
| 2015 |
Lafrance-Vanasse J, Williams GJ, Tainer JA. Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair. Progress in Biophysics and Molecular Biology. 117: 182-93. PMID 25576492 DOI: 10.1016/j.pbiomolbio.2014.12.004 |
0.417 |
|
| 2014 |
Pratt AJ, Shin DS, Merz GE, Rambo RP, Lancaster WA, Dyer KN, Borbat PP, Poole FL, Adams MW, Freed JH, Crane BR, Tainer JA, Getzoff ED. Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 111: E4568-76. PMID 25316790 DOI: 10.1073/Pnas.1308531111 |
0.653 |
|
| 2014 |
Mason AC, Rambo RP, Greer B, Pritchett M, Tainer JA, Cortez D, Eichman BF. A structure-specific nucleic acid-binding domain conserved among DNA repair proteins. Proceedings of the National Academy of Sciences of the United States of America. 111: 7618-23. PMID 24821763 DOI: 10.1073/Pnas.1324143111 |
0.409 |
|
| 2014 |
Tsutakawa SE, Lafrance-Vanasse J, Tainer JA. The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once. Dna Repair. 19: 95-107. PMID 24754999 DOI: 10.1016/J.Dnarep.2014.03.022 |
0.731 |
|
| 2014 |
Groocock LM, Nie M, Prudden J, Moiani D, Wang T, Cheltsov A, Rambo RP, Arvai AS, Hitomi C, Tainer JA, Luger K, Perry JJ, Lazzerini-Denchi E, Boddy MN. RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response. Embo Reports. 15: 601-8. PMID 24714598 DOI: 10.1002/Embr.201338369 |
0.503 |
|
| 2014 |
Shin DS, Pratt AJ, Tainer JA. Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins. Archaea (Vancouver, B.C.). 2014: 206735. PMID 24701133 DOI: 10.1155/2014/206735 |
0.603 |
|
| 2014 |
Williams GJ, Hammel M, Radhakrishnan SK, Ramsden D, Lees-Miller SP, Tainer JA. Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time. Dna Repair. 17: 110-20. PMID 24656613 DOI: 10.1016/J.Dnarep.2014.02.009 |
0.443 |
|
| 2014 |
Deshpande RA, Williams GJ, Limbo O, Williams RS, Kuhnlein J, Lee JH, Classen S, Guenther G, Russell P, Tainer JA, Paull TT. ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. The Embo Journal. 33: 482-500. PMID 24493214 DOI: 10.1002/Embj.201386100 |
0.434 |
|
| 2014 |
Shibata A, Moiani D, Arvai AS, Perry J, Harding SM, Genois MM, Maity R, van Rossum-Fikkert S, Kertokalio A, Romoli F, Ismail A, Ismalaj E, Petricci E, Neale MJ, Bristow RG, ... ... Tainer JA, et al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Molecular Cell. 53: 7-18. PMID 24316220 DOI: 10.1016/J.Molcel.2013.11.003 |
0.497 |
|
| 2014 |
Dyer KN, Hammel M, Rambo RP, Tsutakawa SE, Rodic I, Classen S, Tainer JA, Hura GL. High-throughput SAXS for the characterization of biomolecules in solution: a practical approach. Methods in Molecular Biology (Clifton, N.J.). 1091: 245-58. PMID 24203338 DOI: 10.1007/978-1-62703-691-7_18 |
0.572 |
|
| 2014 |
Zhao W, Saro D, Hammel M, Kwon Y, Xu Y, Rambo RP, Williams GJ, Chi P, Lu L, Pezza RJ, Camerini-Otero RD, Tainer JA, Wang HW, Sung P. Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing. Nucleic Acids Research. 42: 906-17. PMID 24150939 DOI: 10.1093/Nar/Gkt924 |
0.41 |
|
| 2014 |
Rambo R, Hura G, Hammel M, Tainer J. X-ray scattering methods for accurate analyses of flexible complexes Acta Crystallographica Section a Foundations and Advances. 70: C409-C409. DOI: 10.1107/S2053273314095904 |
0.396 |
|
| 2014 |
Tsutakawa S, Arvai A, Sarker A, Querol-Audi J, Finger D, Nogales E, Ivanov I, Cooper P, Grasby J, Tainer J. Defining the Superfamily Conserved Mechanism for Flap Endonucleases FEN1 and XPG Specificity for 5' Flap DNA and DNA Bubbles, Respectively, by Hybrids Methods of Crystallography, SAXS, EM, and Computation Biophysical Journal. 106: 230a. DOI: 10.1016/J.Bpj.2013.11.1343 |
0.772 |
|
| 2013 |
Tsai CL, Tainer JA. Probing DNA by 2-OG-dependent dioxygenase. Cell. 155: 1448-50. PMID 24360270 DOI: 10.1016/j.cell.2013.12.002 |
0.334 |
|
| 2013 |
Hura GL, Tsai CL, Claridge SA, Mendillo ML, Smith JM, Williams GJ, Mastroianni AJ, Alivisatos AP, Putnam CD, Kolodner RD, Tainer JA. DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals. Proceedings of the National Academy of Sciences of the United States of America. 110: 17308-13. PMID 24101514 DOI: 10.1073/Pnas.1308595110 |
0.76 |
|
| 2013 |
Hegde ML, Tsutakawa SE, Hegde PM, Holthauzen LM, Li J, Oezguen N, Hilser VJ, Tainer JA, Mitra S. The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. Journal of Molecular Biology. 425: 2359-71. PMID 23542007 DOI: 10.1016/J.Jmb.2013.03.030 |
0.701 |
|
| 2013 |
Mahaney BL, Hammel M, Meek K, Tainer JA, Lees-Miller SP. XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 91: 31-41. PMID 23442139 DOI: 10.1139/Bcb-2012-0058 |
0.425 |
|
| 2013 |
Perry JJ, Tainer JA. Developing advanced X-ray scattering methods combined with crystallography and computation. Methods (San Diego, Calif.). 59: 363-71. PMID 23376408 DOI: 10.1016/j.ymeth.2013.01.005 |
0.382 |
|
| 2013 |
Tsutakawa SE, Shin DS, Mol CD, Izumi T, Arvai AS, Mantha AK, Szczesny B, Ivanov IN, Hosfield DJ, Maiti B, Pique ME, Frankel KA, Hitomi K, Cunningham RP, Mitra S, ... Tainer JA, et al. Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. The Journal of Biological Chemistry. 288: 8445-55. PMID 23355472 DOI: 10.1074/Jbc.M112.422774 |
0.829 |
|
| 2013 |
Brosey CA, Yan C, Tsutakawa SE, Heller WT, Rambo RP, Tainer JA, Ivanov I, Chazin WJ. A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Research. 41: 2313-27. PMID 23303776 DOI: 10.1093/Nar/Gks1332 |
0.729 |
|
| 2013 |
Dalhus B, Nilsen L, Korvald H, Huffman J, Forstrøm RJ, McMurray CT, Alseth I, Tainer JA, Bjørås M. Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2. Structure (London, England : 1993). 21: 154-66. PMID 23245849 DOI: 10.1016/j.str.2012.11.004 |
0.432 |
|
| 2012 |
Lee KC, Padget K, Curtis H, Cowell IG, Moiani D, Sondka Z, Morris NJ, Jackson GH, Cockell SJ, Tainer JA, Austin CA. MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA. Biology Open. 1: 863-73. PMID 23213480 DOI: 10.1242/bio.20121834 |
0.32 |
|
| 2012 |
Shi K, Kurahashi K, Gao R, Tsutakawa SE, Tainer JA, Pommier Y, Aihara H. Structural basis for recognition of 5′-phosphotyrosine adducts by Tdp2 Nature Structural and Molecular Biology. 19: 1372-1377. PMID 23104058 DOI: 10.1038/Nsmb.2423 |
0.742 |
|
| 2012 |
Limbo O, Moiani D, Kertokalio A, Wyman C, Tainer JA, Russell P. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Nucleic Acids Research. 40: 11435-49. PMID 23080121 DOI: 10.1093/Nar/Gks954 |
0.405 |
|
| 2012 |
Finger LD, Atack JM, Tsutakawa S, Classen S, Tainer J, Grasby J, Shen B. The wonders of flap endonucleases: structure, function, mechanism and regulation. Sub-Cellular Biochemistry. 62: 301-26. PMID 22918592 DOI: 10.1007/978-94-007-4572-8_16 |
0.761 |
|
| 2012 |
Latypov VF, Tubbs JL, Watson AJ, Marriott AS, McGown G, Thorncroft M, Wilkinson OJ, Senthong P, Butt A, Arvai AS, Millington CL, Povey AC, Williams DM, Santibanez-Koref MF, Tainer JA, et al. Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines. Molecular Cell. 47: 50-60. PMID 22658721 DOI: 10.1016/J.Molcel.2012.04.028 |
0.325 |
|
| 2012 |
Kim IK, Kiefer JR, Ho CM, Stegeman RA, Classen S, Tainer JA, Ellenberger T. Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element. Nature Structural & Molecular Biology. 19: 653-6. PMID 22609859 DOI: 10.1038/Nsmb.2305 |
0.355 |
|
| 2012 |
Querol-Audí J, Yan C, Xu X, Tsutakawa SE, Tsai MS, Tainer JA, Cooper PK, Nogales E, Ivanov I. Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability. Proceedings of the National Academy of Sciences of the United States of America. 109: 8528-33. PMID 22586102 DOI: 10.1073/Pnas.1121116109 |
0.723 |
|
| 2012 |
Christie JM, Hitomi K, Arvai AS, Hartfield KA, Mettlen M, Pratt AJ, Tainer JA, Getzoff ED. Structural tuning of the fluorescent protein iLOV for improved photostability. The Journal of Biological Chemistry. 287: 22295-304. PMID 22573334 DOI: 10.1074/Jbc.M111.318881 |
0.513 |
|
| 2012 |
Roberts VA, Pique ME, Hsu S, Li S, Slupphaug G, Rambo RP, Jamison JW, Liu T, Lee JH, Tainer JA, Ten Eyck LF, Woods VL. Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase. Nucleic Acids Research. 40: 6070-81. PMID 22492624 DOI: 10.1093/Nar/Gks291 |
0.7 |
|
| 2012 |
Yamagata A, Milgotina E, Scanlon K, Craig L, Tainer JA, Donnenberg MS. Structure of an essential type IV pilus biogenesis protein provides insights into pilus and type II secretion systems. Journal of Molecular Biology. 419: 110-24. PMID 22387466 DOI: 10.1016/J.Jmb.2012.02.041 |
0.606 |
|
| 2012 |
Patel N, Atack JM, Finger LD, Exell JC, Thompson P, Tsutakawa S, Tainer JA, Williams DM, Grasby JA. Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends. Nucleic Acids Research. 40: 4507-19. PMID 22319208 DOI: 10.1093/Nar/Gks051 |
0.694 |
|
| 2012 |
Sontz PA, Mui TP, Fuss JO, Tainer JA, Barton JK. DNA charge transport as a first step in coordinating the detection of lesions by repair proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 1856-61. PMID 22308447 DOI: 10.1073/Pnas.1120063109 |
0.357 |
|
| 2012 |
Tsutakawa SE, Tainer JA. Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamily. Mechanisms of Ageing and Development. 133: 195-202. PMID 22244820 DOI: 10.1016/J.Mad.2011.11.009 |
0.736 |
|
| 2012 |
Hitomi K, Arvai AS, Yamamoto J, Hitomi C, Teranishi M, Hirouchi T, Yamamoto K, Iwai S, Tainer JA, Hidema J, Getzoff ED. Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants. The Journal of Biological Chemistry. 287: 12060-9. PMID 22170053 DOI: 10.1074/Jbc.M111.244020 |
0.612 |
|
| 2012 |
Grasby JA, Finger LD, Tsutakawa SE, Atack JM, Tainer JA. Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases. Trends in Biochemical Sciences. 37: 74-84. PMID 22118811 DOI: 10.1016/J.Tibs.2011.10.003 |
0.708 |
|
| 2012 |
Kulman J, Tsutakawa S, Bou-Assaf G, Berkowitz S, Light DR, Mezo A, Wang D, Whitlow M, Culyba L, Tainer J, Peters R. Structural Comparability Between Recombinant FVIII-Fc and Its Isolated FVIII and Fc Constituents Blood. 120: 1135-1135. DOI: 10.1182/Blood.V120.21.1135.1135 |
0.658 |
|
| 2012 |
Rosenfeld R, Garcin E, Arvai A, Tainer J, Getzoff E. Nitric oxide synthases in motion Nitric Oxide. 27: S25. DOI: 10.1016/J.Niox.2012.04.090 |
0.568 |
|
| 2012 |
Tainer J. Accurate Structures, Conformations, and Assemblies of Macromolecules in Solution by X-Ray Scattering (SAXS) using Quality Control Parameters Biophysical Journal. 102: 381a. DOI: 10.1016/J.Bpj.2011.11.2084 |
0.421 |
|
| 2011 |
Hartung S, Arvai AS, Wood T, Kolappan S, Shin DS, Craig L, Tainer JA. Ultrahigh resolution and full-length pilin structures with insights for filament assembly, pathogenic functions, and vaccine potential. The Journal of Biological Chemistry. 286: 44254-65. PMID 22027840 DOI: 10.1074/Jbc.M111.297242 |
0.702 |
|
| 2011 |
Tsutakawa SE, Van Wynsberghe AW, Freudenthal BD, Weinacht CP, Gakhar L, Washington MT, Zhuang Z, Tainer JA, Ivanov I. Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA. Proceedings of the National Academy of Sciences of the United States of America. 108: 17672-7. PMID 22006297 DOI: 10.1073/Pnas.1110480108 |
0.669 |
|
| 2011 |
Mui TP, Fuss JO, Ishida JP, Tainer JA, Barton JK. ATP-stimulated, DNA-mediated redox signaling by XPD, a DNA repair and transcription helicase. Journal of the American Chemical Society. 133: 16378-81. PMID 21939244 DOI: 10.1021/Ja207222T |
0.366 |
|
| 2011 |
Hammel M, Rey M, Yu Y, Mani RS, Classen S, Liu M, Pique ME, Fang S, Mahaney BL, Weinfeld M, Schriemer DC, Lees-Miller SP, Tainer JA. XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. The Journal of Biological Chemistry. 286: 32638-50. PMID 21775435 DOI: 10.1074/Jbc.M111.272641 |
0.45 |
|
| 2011 |
Tubbs JL, Tainer JA. P53 conformational switching for selectivity may reveal a general solution for specific DNA binding. The Embo Journal. 30: 2099-100. PMID 21629273 DOI: 10.1038/Emboj.2011.133 |
0.418 |
|
| 2011 |
Fuss JO, Tainer JA. XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. Dna Repair. 10: 697-713. PMID 21571596 DOI: 10.1016/j.dnarep.2011.04.028 |
0.418 |
|
| 2011 |
Trego KS, Chernikova SB, Davalos AR, Perry JJ, Finger LD, Ng C, Tsai MS, Yannone SM, Tainer JA, Campisi J, Cooper PK. The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome. Cell Cycle (Georgetown, Tex.). 10: 1998-2007. PMID 21558802 DOI: 10.4161/Cc.10.12.15878 |
0.465 |
|
| 2011 |
Tsutakawa SE, Classen S, Chapados BR, Arvai AS, Finger LD, Guenther G, Tomlinson CG, Thompson P, Sarker AH, Shen B, Cooper PK, Grasby JA, Tainer JA. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell. 145: 198-211. PMID 21496641 DOI: 10.1016/J.Cell.2011.03.004 |
0.853 |
|
| 2011 |
Perry JJ, Tainer JA. All stressed out without ATM kinase. Science Signaling. 4: pe18. PMID 21467296 DOI: 10.1126/scisignal.2001961 |
0.437 |
|
| 2011 |
Prudden J, Perry JJ, Nie M, Vashisht AA, Arvai AS, Hitomi C, Guenther G, Wohlschlegel JA, Tainer JA, Boddy MN. DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Molecular and Cellular Biology. 31: 2299-310. PMID 21444718 DOI: 10.1128/Mcb.05188-11 |
0.448 |
|
| 2011 |
Williams GJ, Williams RS, Williams JS, Moncalian G, Arvai AS, Limbo O, Guenther G, SilDas S, Hammel M, Russell P, Tainer JA. ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nature Structural & Molecular Biology. 18: 423-31. PMID 21441914 DOI: 10.1038/Nsmb.2038 |
0.326 |
|
| 2011 |
Heideker J, Prudden J, Perry JJ, Tainer JA, Boddy MN. SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability. Plos Genetics. 7: e1001320. PMID 21408210 DOI: 10.1371/Journal.Pgen.1001320 |
0.5 |
|
| 2011 |
Arthur DC, Edwards RA, Tsutakawa S, Tainer JA, Frost LS, Glover JN. Mapping interactions between the RNA chaperone FinO and its RNA targets. Nucleic Acids Research. 39: 4450-63. PMID 21278162 DOI: 10.1093/Nar/Gkr025 |
0.606 |
|
| 2011 |
Wellhauser L, Luna-Chavez C, D'Antonio C, Tainer J, Bear CE. ATP induces conformational changes in the carboxyl-terminal region of ClC-5. The Journal of Biological Chemistry. 286: 6733-41. PMID 21173145 DOI: 10.1074/Jbc.M110.175877 |
0.357 |
|
| 2011 |
Lintner NG, Frankel KA, Tsutakawa SE, Alsbury DL, Copié V, Young MJ, Tainer JA, Lawrence CM. The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system. Journal of Molecular Biology. 405: 939-55. PMID 21093452 DOI: 10.1016/J.Jmb.2010.11.019 |
0.67 |
|
| 2011 |
Hitomi K, Christie JM, Tainer JA, Getzoff ED. 2SA-05 The LOV/PAS-fold : what should we learn?(2SA Photobiophysics promoted by young scientists,The 49th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 51: S14. DOI: 10.2142/Biophys.51.S14_3 |
0.409 |
|
| 2011 |
Williams GJ, Williams RS, Williams JS, Moncalian G, Arvai AS, Limbo O, Guenther G, SilDas S, Hammel M, Russell P, Tainer JA. Erratum: ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair Nature Structural & Molecular Biology. 18: 1084-1084. DOI: 10.1038/Nsmb0911-1084C |
0.34 |
|
| 2010 |
Hammel M, Yu Y, Fang S, Lees-Miller SP, Tainer JA. XLF regulates filament architecture of the XRCC4·ligase IV complex. Structure (London, England : 1993). 18: 1431-42. PMID 21070942 DOI: 10.1016/J.Str.2010.09.009 |
0.347 |
|
| 2010 |
Williams GJ, Lees-Miller SP, Tainer JA. Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks. Dna Repair. 9: 1299-306. PMID 21035407 DOI: 10.1016/J.Dnarep.2010.10.001 |
0.367 |
|
| 2010 |
Dobbs TA, Tainer JA, Lees-Miller SP. A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. Dna Repair. 9: 1307-14. PMID 21030321 DOI: 10.1016/J.Dnarep.2010.09.019 |
0.429 |
|
| 2010 |
Kashiwagi S, Kuraoka I, Fujiwara Y, Hitomi K, Cheng QJ, Fuss JO, Shin DS, Masutani C, Tainer JA, Hanaoka F, Iwai S. Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. Journal of Nucleic Acids. 2010. PMID 20936172 DOI: 10.4061/2010/701472 |
0.64 |
|
| 2010 |
Perry JJ, Shin DS, Tainer JA. Amyotrophic lateral sclerosis. Advances in Experimental Medicine and Biology. 685: 9-20. PMID 20687491 DOI: 10.1007/978-1-4419-6448-9_2 |
0.563 |
|
| 2010 |
Rosenfeld RJ, Bonaventura J, Szymczyna BR, MacCoss MJ, Arvai AS, Yates JR, Tainer JA, Getzoff ED. Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation. The Journal of Biological Chemistry. 285: 31581-9. PMID 20659888 DOI: 10.1074/Jbc.M109.072496 |
0.51 |
|
| 2010 |
Rahal EA, Henricksen LA, Li Y, Williams RS, Tainer JA, Dixon K. ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining. Cell Cycle (Georgetown, Tex.). 9: 2866-77. PMID 20647759 DOI: 10.4161/cc.9.14.12363 |
0.388 |
|
| 2010 |
Lim MS, Ng D, Zong Z, Arvai AS, Taylor RK, Tainer JA, Craig L. Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus-mediated microcolony formation. Molecular Microbiology. 77: 755-70. PMID 20545841 DOI: 10.1111/J.1365-2958.2010.07244.X |
0.594 |
|
| 2010 |
Cotner-Gohara E, Kim IK, Hammel M, Tainer JA, Tomkinson AE, Ellenberger T. Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states Biochemistry. 49: 6165-6176. PMID 20518483 DOI: 10.1021/Bi100503W |
0.449 |
|
| 2010 |
Tubbs JL, Tainer JA. Alkyltransferase-like proteins: molecular switches between DNA repair pathways. Cellular and Molecular Life Sciences : Cmls. 67: 3749-62. PMID 20502938 DOI: 10.1007/S00018-010-0405-8 |
0.4 |
|
| 2010 |
Tainer JA, McCammon JA, Ivanov I. Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor C promotes eukaryotic clamp-loading Journal of the American Chemical Society. 132: 7372-7378. PMID 20455582 DOI: 10.1021/Ja100365X |
0.304 |
|
| 2010 |
Perry JJP, Cotner-Gohara E, Ellenberger T, Tainer JA. Structural dynamics in DNA damage signaling and repair Current Opinion in Structural Biology. 20: 283-294. PMID 20439160 DOI: 10.1016/J.Sbi.2010.03.012 |
0.375 |
|
| 2010 |
Tomlinson CG, Atack JM, Chapados B, Tainer JA, Grasby JA. Substrate recognition and catalysis by flap endonucleases and related enzymes Biochemical Society Transactions. 38: 433-437. PMID 20298197 DOI: 10.1042/Bst0380433 |
0.826 |
|
| 2010 |
Aramini JM, Tubbs JL, Kanugula S, Rossi P, Ertekin A, Maglaqui M, Hamilton K, Ciccosanti CT, Jiang M, Xiao R, Soong TT, Rost B, Acton TB, Everett JK, Pegg AE, ... Tainer JA, et al. Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein. The Journal of Biological Chemistry. 285: 13736-41. PMID 20212037 DOI: 10.1074/Jbc.M109.093591 |
0.444 |
|
| 2010 |
Pretto DI, Tsutakawa S, Brosey CA, Castillo A, Chagot ME, Smith JA, Tainer JA, Chazin WJ. Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry. 49: 2880-9. PMID 20184389 DOI: 10.1021/Bi9019934 |
0.699 |
|
| 2010 |
Das D, Moiani D, Axelrod HL, Miller MD, McMullan D, Jin KK, Abdubek P, Astakhova T, Burra P, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, Ernst D, ... ... Tainer JA, et al. Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair. Journal of Molecular Biology. 397: 647-63. PMID 20122942 DOI: 10.1016/J.Jmb.2010.01.049 |
0.472 |
|
| 2010 |
Rambo RP, Tainer JA. Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering. Current Opinion in Structural Biology. 20: 128-37. PMID 20097063 DOI: 10.1016/j.sbi.2009.12.015 |
0.316 |
|
| 2010 |
Williams JS, Williams RS, Dovey CL, Guenther G, Tainer JA, Russell P. gammaH2A binds Brc1 to maintain genome integrity during S-phase. The Embo Journal. 29: 1136-48. PMID 20094029 DOI: 10.1038/Emboj.2009.413 |
0.425 |
|
| 2010 |
Perry JJ, Shin DS, Getzoff ED, Tainer JA. The structural biochemistry of the superoxide dismutases. Biochimica Et Biophysica Acta. 1804: 245-62. PMID 19914407 DOI: 10.1016/j.bbapap.2009.11.004 |
0.71 |
|
| 2010 |
Hammel M, Yu Y, Mahaney BL, Cai B, Ye R, Phipps BM, Rambo RP, Hura GL, Pelikan M, So S, Abolfath RM, Chen DJ, Lees-Miller SP, Tainer JA. Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. The Journal of Biological Chemistry. 285: 1414-23. PMID 19893054 DOI: 10.1074/Jbc.M109.065615 |
0.431 |
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| 2009 |
Williams RS, Dodson GE, Limbo O, Yamada Y, Williams JS, Guenther G, Classen S, Glover JN, Iwasaki H, Russell P, Tainer JA. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell. 139: 87-99. PMID 19804755 DOI: 10.1016/J.Cell.2009.07.033 |
0.415 |
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| 2009 |
Crowther LJ, Yamagata A, Craig L, Tainer JA, Donnenberg MS. Erratum: The ATPase activity of BfpD is greatly enhanced by zinc and allosteric interactions with other Bfp proteins (The Journal of Biological Chemistry (2005) vol. 280 (24839-24848)) Journal of Biological Chemistry. 284. PMID 19785092 DOI: 10.1074/Jbc.A500253200 |
0.576 |
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| 2009 |
Bernstein NK, Hammel M, Mani RS, Weinfeld M, Pelikan M, Tainer JA, Glover JN. Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase. Nucleic Acids Research. 37: 6161-73. PMID 19671525 DOI: 10.1093/nar/gkp597 |
0.439 |
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| 2009 |
Hura GL, Menon AL, Hammel M, Rambo RP, Poole FL, Tsutakawa SE, Jenney FE, Classen S, Frankel KA, Hopkins RC, Yang SJ, Scott JW, Dillard BD, Adams MW, Tainer JA. Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS). Nature Methods. 6: 606-12. PMID 19620974 DOI: 10.1038/Nmeth.1353 |
0.621 |
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| 2009 |
Tubbs JL, Latypov V, Kanugula S, Butt A, Melikishvili M, Kraehenbuehl R, Fleck O, Marriott A, Watson AJ, Verbeek B, McGown G, Thorncroft M, Santibanez-Koref MF, Millington C, Arvai AS, ... ... Tainer JA, et al. Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature. 459: 808-13. PMID 19516334 DOI: 10.1038/Nature08076 |
0.428 |
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| 2009 |
Perry JJ, Harris RM, Moiani D, Olson AJ, Tainer JA. p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses. Journal of Molecular Biology. 391: 1-11. PMID 19501598 DOI: 10.1016/j.jmb.2009.06.005 |
0.59 |
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| 2009 |
Prudden J, Perry JJ, Arvai AS, Tainer JA, Boddy MN. Molecular mimicry of SUMO promotes DNA repair. Nature Structural & Molecular Biology. 16: 509-16. PMID 19363481 DOI: 10.1038/Nsmb.1582 |
0.505 |
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| 2009 |
Hitomi K, DiTacchio L, Arvai AS, Yamamoto J, Kim ST, Todo T, Tainer JA, Iwai S, Panda S, Getzoff ED. Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes. Proceedings of the National Academy of Sciences of the United States of America. 106: 6962-7. PMID 19359474 DOI: 10.1073/Pnas.0809180106 |
0.651 |
|
| 2009 |
Perry JJ, Hearn AS, Cabelli DE, Nick HS, Tainer JA, Silverman DN. Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis. Biochemistry. 48: 3417-24. PMID 19265433 DOI: 10.1021/Bi8023288 |
0.428 |
|
| 2009 |
Min X, Akella R, He H, Humphreys JM, Tsutakawa SE, Lee SJ, Tainer JA, Cobb MH, Goldsmith EJ. The structure of the MAP2K MEK6 reveals an autoinhibitory dimer. Structure (London, England : 1993). 17: 96-104. PMID 19141286 DOI: 10.1016/J.Str.2008.11.007 |
0.649 |
|
| 2009 |
Dalhus B, Arvai AS, Rosnes I, Olsen ØE, Backe PH, Alseth I, Gao H, Cao W, Tainer JA, Bjørås M. Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair. Nature Structural & Molecular Biology. 16: 138-43. PMID 19136958 DOI: 10.1038/Nsmb.1538 |
0.394 |
|
| 2009 |
Shin DS, Didonato M, Barondeau DP, Hura GL, Hitomi C, Berglund JA, Getzoff ED, Cary SC, Tainer JA. Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis. Journal of Molecular Biology. 385: 1534-55. PMID 19063897 DOI: 10.1016/J.Jmb.2008.11.031 |
0.691 |
|
| 2009 |
Edwards RA, Lee MS, Tsutakawa SE, Williams RS, Nazeer I, Kleiman FE, Tainer JA, Glover JN. The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50 (Biochemistry (2008), 47, 44 (11446-11456)) Biochemistry. 48: 4008. DOI: 10.1021/Bi900462X |
0.635 |
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| 2008 |
Acharya SN, Many AM, Schroeder AP, Kennedy FM, Savytskyy OP, Grubb JT, Vincent JA, Friedle EA, Celerin M, Maillet DS, Palmerini HJ, Greischar MA, Moncalian G, Williams RS, Tainer JA, et al. Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination. Genetics. 180: 1889-907. PMID 18940790 DOI: 10.1534/Genetics.108.092775 |
0.314 |
|
| 2008 |
Williams RS, Moncalian G, Williams JS, Yamada Y, Limbo O, Shin DS, Groocock LM, Cahill D, Hitomi C, Guenther G, Moiani D, Carney JP, Russell P, Tainer JA. Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell. 135: 97-109. PMID 18854158 DOI: 10.1016/J.Cell.2008.08.017 |
0.67 |
|
| 2008 |
Garcin ED, Arvai AS, Rosenfeld RJ, Kroeger MD, Crane BR, Andersson G, Andrews G, Hamley PJ, Mallinder PR, Nicholls DJ, St-Gallay SA, Tinker AC, Gensmantel NP, Mete A, Cheshire DR, ... ... Tainer JA, et al. Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nature Chemical Biology. 4: 700-7. PMID 18849972 DOI: 10.1038/Nchembio.115 |
0.504 |
|
| 2008 |
Edwards RA, Lee MS, Tsutakawa SE, Williams RS, Nazeer I, Kleiman FE, Tainer JA, Glover JN. The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50. Biochemistry. 47: 11446-56. PMID 18842000 DOI: 10.1021/Bi801115G |
0.699 |
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| 2008 |
Fang Q, Noronha AM, Murphy SP, Wilds CJ, Tubbs JL, Tainer JA, Chowdhury G, Guengerich FP, Pegg AE. Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase. Biochemistry. 47: 10892-903. PMID 18803403 DOI: 10.1021/Bi8008664 |
0.351 |
|
| 2008 |
Syson K, Tomlinson C, Chapados BR, Sayers JR, Tainer JA, Williams NH, Grasby JA. Three metal ions participate in the reaction catalyzed by T5 flap endonuclease. The Journal of Biological Chemistry. 283: 28741-6. PMID 18697748 DOI: 10.1074/Jbc.M801264200 |
0.773 |
|
| 2008 |
Pebernard S, Perry JJ, Tainer JA, Boddy MN. Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability. Molecular Biology of the Cell. 19: 4099-109. PMID 18667531 DOI: 10.1091/Mbc.E08-02-0226 |
0.451 |
|
| 2008 |
Fan L, Fuss JO, Cheng QJ, Arvai AS, Hammel M, Roberts VA, Cooper PK, Tainer JA. XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. Cell. 133: 789-800. PMID 18510924 DOI: 10.1016/j.cell.2008.04.030 |
0.303 |
|
| 2008 |
Garcin ED, Hosfield DJ, Desai SA, Haas BJ, Björas M, Cunningham RP, Tainer JA. DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nature Structural & Molecular Biology. 15: 515-22. PMID 18408731 DOI: 10.1038/Nsmb.1414 |
0.774 |
|
| 2008 |
Perry JJ, Tainer JA, Boddy MN. A SIM-ultaneous role for SUMO and ubiquitin. Trends in Biochemical Sciences. 33: 201-8. PMID 18403209 DOI: 10.1016/J.Tibs.2008.02.001 |
0.351 |
|
| 2007 |
Putnam CD, Hammel M, Hura GL, Tainer JA. X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Quarterly Reviews of Biophysics. 40: 191-285. PMID 18078545 DOI: 10.1017/S0033583507004635 |
0.634 |
|
| 2007 |
Roberts BR, Tainer JA, Getzoff ED, Malencik DA, Anderson SR, Bomben VC, Meyers KR, Karplus PA, Beckman JS. Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. Journal of Molecular Biology. 373: 877-90. PMID 17888947 DOI: 10.1016/J.Jmb.2007.07.043 |
0.532 |
|
| 2007 |
Prudden J, Pebernard S, Raffa G, Slavin DA, Perry JJ, Tainer JA, McGowan CH, Boddy MN. SUMO-targeted ubiquitin ligases in genome stability. The Embo Journal. 26: 4089-101. PMID 17762865 DOI: 10.1038/Sj.Emboj.7601838 |
0.432 |
|
| 2007 |
Williams RS, Williams JS, Tainer JA. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template Biochemistry and Cell Biology. 85: 509-520. PMID 17713585 DOI: 10.1139/O07-069 |
0.416 |
|
| 2007 |
Williams R, Sengerová B, Osborne S, Syson K, Ault S, Kilgour A, Chapados BR, Tainer JA, Sayers JR, Grasby JA. Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease. Journal of Molecular Biology. 371: 34-48. PMID 17559871 DOI: 10.1016/J.Jmb.2007.04.063 |
0.82 |
|
| 2007 |
Tubbs JL, Pegg AE, Tainer JA. DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy. Dna Repair. 6: 1100-15. PMID 17485252 DOI: 10.1016/J.Dnarep.2007.03.011 |
0.443 |
|
| 2007 |
Barondeau DP, Kassmann CJ, Tainer JA, Getzoff ED. The case of the missing ring: radical cleavage of a carbon-carbon bond and implications for GFP chromophore biosynthesis. Journal of the American Chemical Society. 129: 3118-26. PMID 17326633 DOI: 10.1021/Ja063983U |
0.499 |
|
| 2007 |
Vijayakumar S, Chapados BR, Schmidt KH, Kolodner RD, Tainer JA, Tomkinson AE. The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase Nucleic Acids Research. 35: 1624-1637. PMID 17308348 DOI: 10.1093/Nar/Gkm006 |
0.84 |
|
| 2007 |
Ivanov I, Tainer JA, McCammon JA. Unraveling the three-metal-ion catalytic mechanism of the DNA repair endonuclease IV Proceedings of the National Academy of Sciences of the United States of America. 104: 1465-1470. PMID 17242363 DOI: 10.1073/Pnas.0603468104 |
0.333 |
|
| 2007 |
Hitomi K, Iwai S, Tainer JA. The intricate structural chemistry of base excision repair machinery: Implications for DNA damage recognition, removal, and repair Dna Repair. 6: 410-428. PMID 17208522 DOI: 10.1016/j.dnarep.2006.10.004 |
0.458 |
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| 2007 |
Tsutakawa SE, Hura GL, Frankel KA, Cooper PK, Tainer JA. Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography. Journal of Structural Biology. 158: 214-23. PMID 17182256 DOI: 10.1016/J.Jsb.2006.09.008 |
0.662 |
|
| 2006 |
Ivanov I, Chapados BR, McCammon JA, Tainer JA. Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications. Nucleic Acids Research. 34: 6023-33. PMID 17071716 DOI: 10.1093/Nar/Gkl744 |
0.831 |
|
| 2006 |
Pascal JM, Tsodikov OV, Hura GL, Song W, Cotner EA, Classen S, Tomkinson AE, Tainer JA, Ellenberger T. A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Molecular Cell. 24: 279-91. PMID 17052461 DOI: 10.1016/J.Molcel.2006.08.015 |
0.439 |
|
| 2006 |
Craig L, Volkmann N, Arvai AS, Pique ME, Yeager M, Egelman EH, Tainer JA. Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Molecular Cell. 23: 651-62. PMID 16949362 DOI: 10.1016/J.Molcel.2006.07.004 |
0.597 |
|
| 2006 |
Sundheim O, Vågbø CB, Bjørås M, Sousa MML, Talstad V, Aas PA, Drabløs F, Krokan HE, Tainer JA, Slupphaug G. Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage Embo Journal. 25: 3389-3397. PMID 16858410 DOI: 10.1038/Sj.Emboj.7601219 |
0.675 |
|
| 2006 |
Perry JJ, Yannone SM, Holden LG, Hitomi C, Asaithamby A, Han S, Cooper PK, Chen DJ, Tainer JA. WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nature Structural & Molecular Biology. 13: 414-22. PMID 16622405 DOI: 10.1038/nsmb1088 |
0.549 |
|
| 2006 |
Fan L, Arvai AS, Cooper PK, Iwai S, Hanaoka F, Tainer JA. Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair Molecular Cell. 22: 27-37. PMID 16600867 DOI: 10.1016/j.molcel.2006.02.017 |
0.442 |
|
| 2006 |
Barondeau DP, Kassmann CJ, Tainer JA, Getzoff ED. Understanding GFP posttranslational chemistry: structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation. Journal of the American Chemical Society. 128: 4685-93. PMID 16594705 DOI: 10.1021/Ja056635L |
0.478 |
|
| 2006 |
Fan L, Kim S, Farr CL, Schaefer KT, Randolph KM, Tainer JA, Kaguni LS. A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Journal of Molecular Biology. 358: 1229-43. PMID 16574152 DOI: 10.1016/J.Jmb.2006.02.073 |
0.366 |
|
| 2006 |
Barondeau DP, Tainer JA, Getzoff ED. Structural evidence for an enolate intermediate in GFP fluorophore biosynthesis. Journal of the American Chemical Society. 128: 3166-8. PMID 16522096 DOI: 10.1021/Ja0552693 |
0.51 |
|
| 2006 |
Garcin-Hosfield ED, Arvai AS, Rosenfeld RJ, Bonaventura J, Scharber MA, Bruns CM, Hosfield DJ, Jane Lloyd S, MacCoss MJ, Yates J, Tiso M, Stuehr DJ, Tainer JA, Getzoff ED. P188. Structural insights into NOS regulatory mechanisms: What? where? how? Nitric Oxide. 14: 77-78. DOI: 10.1016/J.Niox.2006.04.258 |
0.721 |
|
| 2006 |
Garcin-Hosfield E, Arvai A, Rosenfeld R, Crane B, Connolly S, Tinker A, Aberg A, Andersson G, Stuehr D, Wallace A, Tainer J, Getzoff E. P0118. Structural insights into the conformational selectivity of inducible nitric oxide synthase specific inhibitors Nitric Oxide. 14: 55. DOI: 10.1016/J.Niox.2006.04.184 |
0.529 |
|
| 2005 |
Wood TI, Barondeau DP, Hitomi C, Kassmann CJ, Tainer JA, Getzoff ED. Defining the role of arginine 96 in green fluorescent protein fluorophore biosynthesis. Biochemistry. 44: 16211-20. PMID 16331981 DOI: 10.1021/Bi051388J |
0.491 |
|
| 2005 |
Sarker AH, Tsutakawa SE, Kostek S, Ng C, Shin DS, Peris M, Campeau E, Tainer JA, Nogales E, Cooper PK. Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome. Molecular Cell. 20: 187-98. PMID 16246722 DOI: 10.1016/J.Molcel.2005.09.022 |
0.739 |
|
| 2005 |
Putnam CD, Tainer JA. Protein mimicry of DNA and pathway regulation. Dna Repair. 4: 1410-20. PMID 16226493 DOI: 10.1016/J.Dnarep.2005.08.007 |
0.698 |
|
| 2005 |
Williams RS, Tainer JA. A nanomachine for making ends meet: MRN is a flexing scaffold for the repair of DNA double-strand breaks Molecular Cell. 19: 724-726. PMID 16168369 DOI: 10.1016/j.molcel.2005.07.006 |
0.379 |
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| 2005 |
Ayala I, Perry JJ, Szczepanski J, Tainer JA, Vala MT, Nick HS, Silverman DN. Hydrogen bonding in human manganese superoxide dismutase containing 3-fluorotyrosine. Biophysical Journal. 89: 4171-9. PMID 16150974 DOI: 10.1529/Biophysj.105.060616 |
0.365 |
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| 2005 |
Simeoni F, Arvai A, Bello P, Gondeau C, Hopfner KP, Neyroz P, Heitz F, Tainer J, Divita G. Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2. Biochemistry. 44: 11997-2008. PMID 16142897 DOI: 10.1021/Bi050427O |
0.401 |
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| 2005 |
Tubbs JL, Tainer JA, Getzoff ED. Crystallographic structures of Discosoma red fluorescent protein with immature and mature chromophores: linking peptide bond trans-cis isomerization and acylimine formation in chromophore maturation. Biochemistry. 44: 9833-40. PMID 16026155 DOI: 10.1021/Bi0472907 |
0.479 |
|
| 2005 |
Huffman JL, Sundheim O, Tainer JA. DNA base damage recognition and removal: new twists and grooves. Mutation Research. 577: 55-76. PMID 15941573 DOI: 10.1016/j.mrfmmm.2005.03.012 |
0.419 |
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| 2005 |
Crowther LJ, Yamagata A, Craig L, Tainer JA, Donnenberg MS. The ATPase activity of BfpD is greatly enhanced by zinc and allosteric interactions with other Bfp proteins. The Journal of Biological Chemistry. 280: 24839-48. PMID 15866879 DOI: 10.1074/Jbc.M500253200 |
0.634 |
|
| 2005 |
Barondeau DP, Kassmann CJ, Tainer JA, Getzoff ED. Understanding GFP chromophore biosynthesis: controlling backbone cyclization and modifying post-translational chemistry. Biochemistry. 44: 1960-70. PMID 15697221 DOI: 10.1021/Bi0479205 |
0.528 |
|
| 2005 |
Tainer J. Envisioning new targets and new approaches for molecular-based cancer therapeutics Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1087 |
0.547 |
|
| 2004 |
Manuel RC, Hitomi K, Arvai AS, House PG, Kurtz AJ, Dodson ML, McCullough AK, Tainer JA, Lloyd RS. Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase. The Journal of Biological Chemistry. 279: 46930-9. PMID 15326180 DOI: 10.1074/jbc.M403944200 |
0.382 |
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| 2004 |
Shin DS, Chahwan C, Huffman JL, Tainer JA. Structure and function of the double-strand break repair machinery. Dna Repair. 3: 863-73. PMID 15279771 DOI: 10.1016/J.Dnarep.2004.03.022 |
0.671 |
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| 2004 |
Daniels DS, Woo TT, Luu KX, Noll DM, Clarke ND, Pegg AE, Tainer JA. DNA binding and nucleotide flipping by the human DNA repair protein AGT. Nature Structural & Molecular Biology. 11: 714-20. PMID 15221026 DOI: 10.1038/Nsmb791 |
0.788 |
|
| 2004 |
Barondeau DP, Kassmann CJ, Bruns CK, Tainer JA, Getzoff ED. Nickel superoxide dismutase structure and mechanism. Biochemistry. 43: 8038-47. PMID 15209499 DOI: 10.1021/Bi0496081 |
0.544 |
|
| 2004 |
Garcin ED, Bruns CM, Lloyd SJ, Hosfield DJ, Tiso M, Gachhui R, Stuehr DJ, Tainer JA, Getzoff ED. Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase. The Journal of Biological Chemistry. 279: 37918-27. PMID 15208315 DOI: 10.1074/Jbc.M406204200 |
0.746 |
|
| 2004 |
Greenleaf WB, Perry JJ, Hearn AS, Cabelli DE, Lepock JR, Stroupe ME, Tainer JA, Nick HS, Silverman DN. Role of hydrogen bonding in the active site of human manganese superoxide dismutase. Biochemistry. 43: 7038-45. PMID 15170341 DOI: 10.1021/Bi049888K |
0.372 |
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| 2004 |
de Jager M, Trujillo KM, Sung P, Hopfner KP, Carney JP, Tainer JA, Connelly JC, Leach DR, Kanaar R, Wyman C. Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair protein complex. Journal of Molecular Biology. 339: 937-49. PMID 15165861 DOI: 10.1016/J.Jmb.2004.04.014 |
0.318 |
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| 2004 |
Craig L, Pique ME, Tainer JA. Type IV pilus structure and bacterial pathogenicity. Nature Reviews. Microbiology. 2: 363-78. PMID 15100690 DOI: 10.1038/Nrmicro885 |
0.564 |
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| 2004 |
Arthur LM, Gustausson K, Hopfner KP, Carson CT, Stracker TH, Karcher A, Felton D, Weitzman MD, Tainer J, Carney JP. Structural and functional analysis of Mre11-3. Nucleic Acids Research. 32: 1886-93. PMID 15047855 DOI: 10.1093/Nar/Gkh343 |
0.539 |
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| 2004 |
Qiu J, Liu R, Chapados BR, Sherman M, Tainer JA, Shen B. Interaction interface of human flap endonuclease-1 with its DNA substrates. The Journal of Biological Chemistry. 279: 24394-402. PMID 15037610 DOI: 10.1074/Jbc.M401464200 |
0.833 |
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| 2004 |
Chapados BR, Hosfield DJ, Han S, Qiu J, Yelent B, Shen B, Tainer JA. Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair. Cell. 116: 39-50. PMID 14718165 DOI: 10.1016/S0092-8674(03)01036-5 |
0.856 |
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| 2004 |
Moncalian G, Lengsfeld B, Bhaskara V, Hopfner KP, Karcher A, Alden E, Tainer JA, Paull TT. The rad50 signature motif: essential to ATP binding and biological function. Journal of Molecular Biology. 335: 937-51. PMID 14698290 DOI: 10.1016/J.Jmb.2003.11.026 |
0.37 |
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| 2004 |
Hopfner KP, Tainer JA. Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures. Current Opinion in Structural Biology. 13: 249-55. PMID 12727520 DOI: 10.1016/S0959-440X(03)00037-X |
0.364 |
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| 2003 |
Barondeau DP, Putnam CD, Kassmann CJ, Tainer JA, Getzoff ED. Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures. Proceedings of the National Academy of Sciences of the United States of America. 100: 12111-6. PMID 14523232 DOI: 10.1073/Pnas.2133463100 |
0.682 |
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| 2003 |
DiDonato M, Craig L, Huff ME, Thayer MM, Cardoso RM, Kassmann CJ, Lo TP, Bruns CK, Powers ET, Kelly JW, Getzoff ED, Tainer JA. ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization. Journal of Molecular Biology. 332: 601-15. PMID 12963370 DOI: 10.1016/S0022-2836(03)00889-1 |
0.795 |
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| 2003 |
Shin DS, Pellegrini L, Daniels DS, Yelent B, Craig L, Bates D, Yu DS, Shivji MK, Hitomi C, Arvai AS, Volkmann N, Tsuruta H, Blundell TL, Venkitaraman AR, Tainer JA. Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. The Embo Journal. 22: 4566-76. PMID 12941707 DOI: 10.1093/Emboj/Cdg429 |
0.846 |
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| 2003 |
Huffman JL, Li H, White RH, Tainer JA. Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii. Journal of Molecular Biology. 331: 885-96. PMID 12909016 DOI: 10.1016/S0022-2836(03)00789-7 |
0.316 |
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| 2003 |
Craig L, Taylor RK, Pique ME, Adair BD, Arvai AS, Singh M, Lloyd SJ, Shin DS, Getzoff ED, Yeager M, Forest KT, Tainer JA. Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin. Molecular Cell. 11: 1139-50. PMID 12769840 DOI: 10.1016/S1097-2765(03)00170-9 |
0.76 |
|
| 2003 |
Friedberg EC, Hanaoka F, Tanaka K, Wilson SH, Yasui A, Sugasawa K, Matsunaga T, Madura K, Sweder K, Van Houten B, Cooper P, Shiomi T, Grollman A, Nakabeppu Y, Wallace S, ... ... Tainer J, et al. Report on the First US-Japan DNA Repair Meeting Sendai, Japan, October 27-31, 2002 Dna Repair. 2: 639-652. PMID 12713820 DOI: 10.1016/S1568-7864(03)00038-7 |
0.451 |
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| 2003 |
Cardoso RM, Daniels DS, Bruns CM, Tainer JA. Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum. Proteins. 51: 137-46. PMID 12596270 DOI: 10.1002/Prot.10345 |
0.715 |
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| 2003 |
Aoyagi M, Arvai AS, Tainer JA, Getzoff ED. Structural basis for endothelial nitric oxide synthase binding to calmodulin. The Embo Journal. 22: 766-75. PMID 12574113 DOI: 10.1093/Emboj/Cdg078 |
0.516 |
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| 2003 |
Brudler R, Hitomi K, Daiyasu H, Toh H, Kucho K, Ishiura M, Kanehisa M, Roberts VA, Todo T, Tainer JA, Getzoff ED. Identification of a new cryptochrome class. Structure, function, and evolution. Molecular Cell. 11: 59-67. PMID 12535521 DOI: 10.1016/S1097-2765(03)00008-X |
0.601 |
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| 2003 |
DiDonato M, Craig L, Huff ME, Thayer MM, Cardoso RM, Kassmann CJ, Lo TP, Bruns CK, Powers ET, Kelly JW, Getzoff ED, Tainer JA. Erratum to “ALS Mutants of Human Superoxide Dismutase form Fibrous Aggregates via Framework Destabilization” [J. Mol. Biol. 332 (2003) 601–615] Journal of Molecular Biology. 334: 175. DOI: 10.1016/S0022-2836(03)01190-2 |
0.768 |
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| 2002 |
Cardoso RM, Thayer MM, DiDonato M, Lo TP, Bruns CK, Getzoff ED, Tainer JA. Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase. Journal of Molecular Biology. 324: 247-56. PMID 12441104 DOI: 10.1016/S0022-2836(02)01090-2 |
0.769 |
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| 2002 |
Rosenfeld RJ, Garcin ED, Panda K, Andersson G, Aberg A, Wallace AV, Morris GM, Olson AJ, Stuehr DJ, Tainer JA, Getzoff ED. Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency. Biochemistry. 41: 13915-25. PMID 12437348 DOI: 10.1021/Bi026313J |
0.663 |
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| 2002 |
Hopfner KP, Craig L, Moncalian G, Zinkel RA, Usui T, Owen BA, Karcher A, Henderson B, Bodmer JL, McMurray CT, Carney JP, Petrini JH, Tainer JA. The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature. 418: 562-6. PMID 12152085 DOI: 10.1038/Nature00922 |
0.702 |
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| 2002 |
Barondeau DP, Kassmann CJ, Tainer JA, Getzoff ED. Structural chemistry of a green fluorescent protein Zn biosensor. Journal of the American Chemical Society. 124: 3522-4. PMID 11929238 DOI: 10.1021/Ja0176954 |
0.493 |
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| 2002 |
Han S, Tainer JA. The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases. International Journal of Medical Microbiology : Ijmm. 291: 523-9. PMID 11890553 DOI: 10.1078/1438-4221-00162 |
0.357 |
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| 2002 |
Hopfner KP, Putnam CD, Tainer JA. DNA double-strand break repair from head to tail. Current Opinion in Structural Biology. 12: 115-22. PMID 11839498 DOI: 10.1016/S0959-440X(02)00297-X |
0.703 |
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| 2002 |
Mol CD, Arvai AS, Begley TJ, Cunningham RP, Tainer JA. Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases. Journal of Molecular Biology. 315: 373-84. PMID 11786018 DOI: 10.1006/Jmbi.2001.5264 |
0.772 |
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| 2002 |
Adak S, Bilwes AM, Panda K, Hosfield D, Aulak KS, McDonald JF, Tainer JA, Getzoff ED, Crane BR, Stuehr DJ. Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans. Proceedings of the National Academy of Sciences of the United States of America. 99: 107-12. PMID 11756668 DOI: 10.1073/Pnas.012470099 |
0.756 |
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| 2002 |
Castagnetto JM, Hennessy SW, Roberts VA, Getzoff ED, Tainer JA, Pique ME. MDB: the Metalloprotein Database and Browser at The Scripps Research Institute. Nucleic Acids Research. 30: 379-82. PMID 11752342 DOI: 10.1093/Nar/30.1.379 |
0.502 |
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| 2002 |
Garcin ED, Lloyd SJ, Arvai AS, Tsuruta H, Meade A, Stuehr DJ, Tainer JA, Getzoff ED. Crystal structures of oxygenase and reductase modules of nitric oxide synthase: enzyme mechanism and regulation of electron transfer revealed Acta Crystallographica Section a Foundations of Crystallography. 58: c292-c292. DOI: 10.1107/S0108767302096666 |
0.486 |
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| 2001 |
Aoyagi M, Arvai AS, Ghosh S, Stuehr DJ, Tainer JA, Getzoff ED. Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457. Biochemistry. 40: 12826-32. PMID 11669619 DOI: 10.1021/Bi011183K |
0.529 |
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| 2001 |
Hearn AS, Stroupe ME, Cabelli DE, Lepock JR, Tainer JA, Nick HS, Silverman DN. Kinetic analysis of product inhibition in human manganese superoxide dismutase. Biochemistry. 40: 12051-8. PMID 11580280 DOI: 10.1021/Bi011047F |
0.356 |
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| 2001 |
Hosfield DJ, Daniels DS, Mol CD, Putnam CD, Parikh SS, Tainer JA. DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. Progress in Nucleic Acid Research and Molecular Biology. 68: 315-47. PMID 11554309 DOI: 10.1016/S0079-6603(01)68110-8 |
0.833 |
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| 2001 |
Tainer JA. Structural implications of BER enzymes: dragons dancing--the structural biology of DNA base excision repair. Progress in Nucleic Acid Research and Molecular Biology. 68: 299-304. PMID 11554306 DOI: 10.1016/S0079-6603(01)68108-X |
0.406 |
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| 2001 |
Putnam CD, Clancy SB, Tsuruta H, Gonzalez S, Wetmur JG, Tainer JA. Structure and mechanism of the RuvB Holliday junction branch migration motor. Journal of Molecular Biology. 311: 297-310. PMID 11478862 DOI: 10.1006/Jmbi.2001.4852 |
0.698 |
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| 2001 |
Chung JH, Suh MJ, Park YI, Tainer JA, Han YS. Repair activities of 8-oxoguanine DNA glycosylase from Archaeoglobus fulgidus, a hyperthermophilic archaeon. Mutation Research. 486: 99-111. PMID 11425515 DOI: 10.1016/S0921-8777(01)00081-7 |
0.366 |
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| 2001 |
Hopfner KP, Karcher A, Craig L, Woo TT, Carney JP, Tainer JA. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell. 105: 473-85. PMID 11371344 DOI: 10.1016/S0092-8674(01)00335-X |
0.716 |
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| 2001 |
Chapados BR, Chai Q, Hosfield DJ, Qiu J, Shen B, Tainer JA. Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication. Journal of Molecular Biology. 307: 541-56. PMID 11254381 DOI: 10.1006/Jmbi.2001.4494 |
0.832 |
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| 2001 |
Hopfner KP, Tainer JA. DNA mismatch repair: the hands of a genome guardian. Structure (London, England : 1993). 8: R237-41. PMID 11188699 DOI: 10.1016/S0969-2126(00)00545-1 |
0.419 |
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| 2000 |
Hopfner KP, Parikh SS, Tainer JA. Envisioning the fourth dimension of the genetic code: the structural biology of macromolecular recognition and conformational switching in DNA repair. Cold Spring Harbor Symposia On Quantitative Biology. 65: 113-26. PMID 12760026 DOI: 10.1101/Sqb.2000.65.113 |
0.68 |
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| 2000 |
Hopfner KP, Karcher A, Shin D, Fairley C, Tainer JA, Carney JP. Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine. Journal of Bacteriology. 182: 6036-41. PMID 11029422 DOI: 10.1128/Jb.182.21.6036-6041.2000 |
0.614 |
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| 2000 |
Mol CD, Hosfield DJ, Tainer JA. Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means. Mutation Research. 460: 211-29. PMID 10946230 DOI: 10.1016/S0921-8777(00)00028-8 |
0.844 |
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| 2000 |
Parikh SS, Putnam CD, Tainer JA. Lessons learned from structural results on uracil-DNA glycosylase. Mutation Research. 460: 183-99. PMID 10946228 DOI: 10.1016/S0921-8777(00)00026-4 |
0.807 |
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| 2000 |
Daniels DS, Tainer JA. Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O(6)-alkylguanine-DNA alkyltransferase. Mutation Research. 460: 151-63. PMID 10946226 DOI: 10.1016/S0921-8777(00)00024-0 |
0.791 |
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| 2000 |
Tainer JA, Friedberg EC. Dancing with the elephants: envisioning the structural biology of DNA repair pathways. Mutation Research. 460: 139-41. PMID 10946224 DOI: 10.1016/S0921-8777(00)00037-9 |
0.39 |
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| 2000 |
Hopfner KP, Karcher A, Shin DS, Craig L, Arthur LM, Carney JP, Tainer JA. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell. 101: 789-800. PMID 10892749 DOI: 10.1016/S0092-8674(00)80890-9 |
0.773 |
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| 2000 |
Parikh SS, Walcher G, Jones GD, Slupphaug G, Krokan HE, Blackburn GM, Tainer JA. Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects. Proceedings of the National Academy of Sciences of the United States of America. 97: 5083-8. PMID 10805771 DOI: 10.1073/Pnas.97.10.5083 |
0.811 |
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| 2000 |
Crane BR, Arvai AS, Ghosh S, Getzoff ED, Stuehr DJ, Tainer JA. Structures of the N(omega)-hydroxy-L-arginine complex of inducible nitric oxide synthase oxygenase dimer with active and inactive pterins. Biochemistry. 39: 4608-21. PMID 10769116 DOI: 10.1021/Bi992409A |
0.483 |
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| 2000 |
Daniels DS, Mol CD, Arvai AS, Kanugula S, Pegg AE, Tainer JA. Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding. The Embo Journal. 19: 1719-30. PMID 10747039 DOI: 10.1093/Emboj/19.7.1719 |
0.851 |
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| 2000 |
Mol CD, Izumi T, Mitra S, Tainer JA. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]. Nature. 403: 451-6. PMID 10667800 DOI: 10.1038/35000249 |
0.778 |
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| 2000 |
Putnam CD, Arvai AS, Bourne Y, Tainer JA. Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism. Journal of Molecular Biology. 296: 295-309. PMID 10656833 DOI: 10.1006/Jmbi.1999.3458 |
0.622 |
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| 2000 |
Putnam CD, Tainer JA. The food of sweet and bitter fancy. Nature Structural Biology. 7: 17-8. PMID 10625418 DOI: 10.1038/71211 |
0.63 |
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| 2000 |
Mol CD, Izumi T, Mitra S, Tainer JA. Erratum: DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination Nature. 404: 525-525. DOI: 10.1038/35006693 |
0.761 |
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| 1999 |
Crane BR, Rosenfeld RJ, Arvai AS, Ghosh DK, Ghosh S, Tainer JA, Stuehr DJ, Getzoff ED. N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization. The Embo Journal. 18: 6271-81. PMID 10562539 DOI: 10.1093/Emboj/18.22.6271 |
0.53 |
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| 1999 |
Ghosh DK, Crane BR, Ghosh S, Wolan D, Gachhui R, Crooks C, Presta A, Tainer JA, Getzoff ED, Stuehr DJ. Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction. The Embo Journal. 18: 6260-70. PMID 10562538 DOI: 10.1093/Emboj/18.22.6260 |
0.515 |
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| 1999 |
Han S, Craig JA, Putnam CD, Carozzi NB, Tainer JA. Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex. Nature Structural Biology. 6: 932-6. PMID 10504727 DOI: 10.1038/13300 |
0.625 |
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| 1999 |
Adak S, Crooks C, Wang Q, Crane BR, Tainer JA, Getzoff ED, Stuehr DJ. Tryptophan 409 controls the activity of neuronal nitric-oxide synthase by regulating nitric oxide feedback inhibition. The Journal of Biological Chemistry. 274: 26907-11. PMID 10480900 DOI: 10.1074/Jbc.274.38.26907 |
0.508 |
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| 1999 |
Hosfield DJ, Guan Y, Haas BJ, Cunningham RP, Tainer JA. Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis. Cell. 98: 397-408. PMID 10458614 DOI: 10.1016/S0092-8674(00)81968-6 |
0.775 |
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| 1999 |
Ghosh S, Wolan D, Adak S, Crane BR, Kwon NS, Tainer JA, Getzoff ED, Stuehr DJ. Mutational analysis of the tetrahydrobiopterin-binding site in inducible nitric-oxide synthase. The Journal of Biological Chemistry. 274: 24100-12. PMID 10446182 DOI: 10.1074/Jbc.274.34.24100 |
0.566 |
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| 1999 |
Pellequer JL, Chen Sw, Roberts VA, Tainer JA, Getzoff ED. Unraveling the effect of changes in conformation and compactness at the antibody V(L)-V(H) interface upon antigen binding. Journal of Molecular Recognition : Jmr. 12: 267-75. PMID 10440998 DOI: 10.1002/(Sici)1099-1352(199907/08)12:4<267::Aid-Jmr465>3.0.Co;2-9 |
0.467 |
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| 1999 |
Mol CD, Parikh SS, Putnam CD, Lo TP, Tainer JA. DNA repair mechanisms for the recognition and removal of damaged DNA bases. Annual Review of Biophysics and Biomolecular Structure. 28: 101-28. PMID 10410797 DOI: 10.1146/Annurev.Biophys.28.1.101 |
0.836 |
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| 1999 |
Shroyer MJ, Bennett SE, Putnam CD, Tainer JA, Mosbaugh DW. Mutation of an active site residue in Escherichia coli uracil-DNA glycosylase: effect on DNA binding, uracil inhibition and catalysis. Biochemistry. 38: 4834-45. PMID 10200172 DOI: 10.1021/Bi982986J |
0.694 |
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| 1999 |
Putnam CD, Shroyer MJ, Lundquist AJ, Mol CD, Arvai AS, Mosbaugh DW, Tainer JA. Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase. Journal of Molecular Biology. 287: 331-46. PMID 10080896 DOI: 10.1006/Jmbi.1999.2605 |
0.839 |
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| 1999 |
Parikh SS, Mol CD, Hosfield DJ, Tainer JA. Envisioning the molecular choreography of DNA base excision repair. Current Opinion in Structural Biology. 9: 37-47. PMID 10047578 DOI: 10.1016/S0959-440X(99)80006-2 |
0.843 |
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| 1999 |
Haas BJ, Sandigursky M, Tainer JA, Franklin WA, Cunningham RP. Purification and Characterization ofThermotoga maritima Endonuclease IV, a Thermostable Apurinic/Apyrimidinic Endonuclease and 3′-Repair Diesterase Journal of Bacteriology. 181: 2834-2839. DOI: 10.1128/jb.181.9.2834-2839.1999 |
0.336 |
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| 1998 |
Guan Y, Manuel RC, Arvai AS, Parikh SS, Mol CD, Miller JH, Lloyd S, Tainer JA. MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nature Structural Biology. 5: 1058-64. PMID 9846876 DOI: 10.1038/4168 |
0.847 |
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| 1998 |
Hosfield DJ, Mol CD, Shen B, Tainer JA. Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity. Cell. 95: 135-46. PMID 9778254 DOI: 10.1016/S0092-8674(00)81789-4 |
0.857 |
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| 1998 |
Hosfield DJ, Frank G, Weng Y, Tainer JA, Shen B. Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1. The Journal of Biological Chemistry. 273: 27154-61. PMID 9765234 DOI: 10.1074/Jbc.273.42.27154 |
0.754 |
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| 1998 |
Schnecke V, Swanson CA, Getzoff ED, Tainer JA, Kuhn LA. Screening a peptidyl database for potential ligands to proteins with side-chain flexibility. Proteins. 33: 74-87. PMID 9741846 DOI: 10.1002/(Sici)1097-0134(19981001)33:1<74::Aid-Prot7>3.0.Co;2-L |
0.53 |
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| 1998 |
Parikh SS, Mol CD, Slupphaug G, Bharati S, Krokan HE, Tainer JA. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. The Embo Journal. 17: 5214-26. PMID 9724657 DOI: 10.1093/Emboj/17.17.5214 |
0.849 |
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| 1998 |
Shen B, Qiu J, Hosfield D, Tainer JA. Flap endonuclease homologs in archaebacteria exist as independent proteins. Trends in Biochemical Sciences. 23: 171-3. PMID 9612080 DOI: 10.1016/S0968-0004(98)01199-2 |
0.635 |
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| 1998 |
Crane BR, Arvai AS, Ghosh DK, Wu C, Getzoff ED, Stuehr DJ, Tainer JA. Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science (New York, N.Y.). 279: 2121-6. PMID 9516116 DOI: 10.1126/Science.279.5359.2121 |
0.516 |
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| 1998 |
Marceau M, Forest K, Béretti JL, Tainer J, Nassif X. Consequences of the loss of O-linked glycosylation of meningococcal type IV pilin on piliation and pilus-mediated adhesion. Molecular Microbiology. 27: 705-15. PMID 9515697 DOI: 10.1046/J.1365-2958.1998.00706.X |
0.314 |
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| 1997 |
Zu JS, Deng HX, Lo TP, Mitsumoto H, Ahmed MS, Hung WY, Cai ZJ, Tainer JA, Siddique T. Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis. Neurogenetics. 1: 65-71. PMID 10735277 DOI: 10.1007/S100480050010 |
0.73 |
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| 1997 |
Parikh SS, Mol CD, Tainer JA. Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway. Structure (London, England : 1993). 5: 1543-50. PMID 9438868 DOI: 10.1016/S0969-2126(97)00303-1 |
0.829 |
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| 1997 |
Gorman MA, Morera S, Rothwell DG, de La Fortelle E, Mol CD, Tainer JA, Hickson ID, Freemont PS. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. The Embo Journal. 16: 6548-58. PMID 9351835 DOI: 10.1093/Emboj/16.21.6548 |
0.762 |
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| 1997 |
Crane BR, Arvai AS, Gachhui R, Wu C, Ghosh DK, Getzoff ED, Stuehr DJ, Tainer JA. The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science (New York, N.Y.). 278: 425-31. PMID 9334294 DOI: 10.1126/Science.278.5337.425 |
0.528 |
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| 1997 |
Fisher CL, Cabelli DE, Hallewell RA, Beroza P, Lo TP, Getzoff ED, Tainer JA. Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase. Proteins. 29: 103-12. PMID 9294870 DOI: 10.1002/(Sici)1097-0134(199709)29:1<103::Aid-Prot8>3.0.Co;2-G |
0.766 |
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| 1997 |
Boissinot M, Karnas S, Lepock JR, Cabelli DE, Tainer JA, Getzoff ED, Hallewell RA. Function of the Greek key connection analysed using circular permutants of superoxide dismutase. The Embo Journal. 16: 2171-8. PMID 9171332 DOI: 10.1093/Emboj/16.9.2171 |
0.497 |
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| 1996 |
Bourne Y, Redford SM, Steinman HM, Lepock JR, Tainer JA, Getzoff ED. Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 93: 12774-9. PMID 8917495 DOI: 10.1073/Pnas.93.23.12774 |
0.541 |
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| 1996 |
Slupphaug G, Mol CD, Kavli B, Arvai AS, Krokan HE, Tainer JA. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature. 384: 87-92. PMID 8900285 DOI: 10.1038/384087A0 |
0.837 |
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| 1996 |
Mol CD, Harris JM, McIntosh EM, Tainer JA. Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits. Structure (London, England : 1993). 4: 1077-92. PMID 8805593 DOI: 10.1016/S0969-2126(96)00114-1 |
0.762 |
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| 1996 |
Forest KT, Bernstein SL, Getzoff ED, So M, Tribbick G, Geysen HM, Deal CD, Tainer JA. Assembly and antigenicity of the Neisseria gonorrhoeae pilus mapped with antibodies. Infection and Immunity. 64: 644-52. PMID 8550220 DOI: 10.1128/Iai.64.2.644-652.1996 |
0.471 |
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| 1996 |
Lo TP, Canestrelli IL, Tainer JA, Getzoff ED. Crystallization of superoxide dismutase from a halophilic organism Acta Crystallographica Section a Foundations of Crystallography. 52: C136-C136. DOI: 10.1107/S0108767396093804 |
0.423 |
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| 1996 |
Mol CD, Slupphaug G, Arvai AS, Tainer JA, Kavli B, Krokan HE. Structural basis for the removal and exclusion of uracil from DNA Acta Crystallographica Section a Foundations of Crystallography. 52: C157-C158. DOI: 10.1107/S010876739609294X |
0.817 |
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| 1996 |
Tainer JA, Parge HE, Forest KT, Getzoff ED. Dancing with the elephant: structure and assembly of the fiber-forming protein pilin Acta Crystallographica Section a Foundations of Crystallography. 52: C176-C176. DOI: 10.1107/S0108767396092252 |
0.475 |
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| 1996 |
Kavli B, Slupphaug G, Mol CD, Arvai AS, Peterson SB, Tainer JA, Krokan HE. Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase. The Embo Journal. 15: 3442-3447. DOI: 10.1002/J.1460-2075.1996.Tb00710.X |
0.825 |
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| 1995 |
Kuhn LA, Swanson CA, Pique ME, Tainer JA, Getzoff ED. Atomic and residue hydrophilicity in the context of folded protein structures. Proteins. 23: 536-47. PMID 8749849 DOI: 10.1002/Prot.340230408 |
0.495 |
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| 1995 |
Mol CD, Kuo CF, Thayer MM, Cunningham RP, Tainer JA. Structure and function of the multifunctional DNA-repair enzyme exonuclease III. Nature. 374: 381-6. PMID 7885481 DOI: 10.1038/374381A0 |
0.758 |
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| 1995 |
Tainer JA, Thayer MM, Cunningham RP. DNA repair proteins Current Opinion in Structural Biology. 5: 20-26. PMID 7773744 DOI: 10.1016/0959-440X(95)80005-L |
0.414 |
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| 1995 |
Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE, Tainer JA. Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis. Cell. 80: 869-78. PMID 7697717 DOI: 10.1016/0092-8674(95)90290-2 |
0.834 |
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| 1995 |
Mol CD, Arvai AS, Sanderson RJ, Slupphaug G, Kavli B, Krokan HE, Mosbaugh DW, Tainer JA. Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA. Cell. 82: 701-8. PMID 7671300 DOI: 10.1016/0092-8674(95)90467-0 |
0.833 |
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| 1995 |
Barzilay G, Mol CD, Robson CN, Walker LJ, Cunningham RP, Tainer JA, Hickson ID. Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1. Nature Structural Biology. 2: 561-8. PMID 7664124 DOI: 10.1038/Nsb0795-561 |
0.743 |
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| 1995 |
Phillips JP, Tainer JA, Getzoff ED, Boulianne GL, Kirby K, Hilliker AJ. Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium. Proceedings of the National Academy of Sciences of the United States of America. 92: 8574-8. PMID 7567977 DOI: 10.1073/Pnas.92.19.8574 |
0.503 |
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| 1995 |
Parge HE, Forest KT, Hickey MJ, Christensen DA, Getzoff ED, Tainer JA. Structure of the fibre-forming protein pilin at 2.6 A resolution. Nature. 378: 32-8. PMID 7477282 DOI: 10.1038/378032A0 |
0.491 |
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| 1995 |
Thayer MM, Ahern H, Xing D, Cunningham RP, Tainer JA. Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure. The Embo Journal. 14: 4108-4120. DOI: 10.1002/j.1460-2075.1995.tb00083.x |
0.437 |
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| 1994 |
Kuo CF, Mol CD, Thayer MM, Cunningham RP, Tainer JA. Structure and function of the DNA repair enzyme exonuclease III from E. coli. Annals of the New York Academy of Sciences. 726: 223-34; discussion 2. PMID 8092679 DOI: 10.1111/J.1749-6632.1994.Tb52820.X |
0.721 |
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| 1994 |
Fisher CL, Cabelli DE, Tainer JA, Hallewell RA, Getzoff ED. The role of arginine 143 in the electrostatics and mechanism of Cu,Zn superoxide dismutase: computational and experimental evaluation by mutational analysis. Proteins. 19: 24-34. PMID 8066083 DOI: 10.1002/Prot.340190105 |
0.495 |
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| 1993 |
Kuo CF, McRee DE, Cunningham RP, Tainer JA. Purification, crystallization and space group determination of DNA repair enzyme exonuclease III from E. coli Journal of Molecular Biology. 229: 239-242. PMID 8421304 DOI: 10.1006/jmbi.1993.1021 |
0.329 |
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| 1993 |
Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, Getzoff ED, Hu P, Herzfeldt B, Roos RP, Warner C, Deng G, Soriano E, Smyth C, Parge HE, et al. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase Science. 261: 1047-1051. PMID 8351519 DOI: 10.1126/Science.8351519 |
0.532 |
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| 1993 |
Tainer JA, Cunningham RP. Molecular recognition in DNA-binding proteins and enzymes Current Opinion in Biotechnology. 4: 474-483. PMID 7763979 DOI: 10.1016/0958-1669(93)90015-O |
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| 1993 |
Tainer JA, Kuo CF, McRee DE, Fisher CL, O'Handle S, Cunningham RP. Crystallographic structures of metalloenzymes for dna repair: The [4fe-4s] enzyme endonuclease iii structure as a prototype for dna n-glycosylase and ap lyase Protein Engineering, Design and Selection. 6: 39. DOI: 10.1093/protein/6.Supplement.39 |
0.38 |
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| 1993 |
Kuhn LA, Swanson CA, Siani MA, Tainer JA, Getzoff ED. Amino acid hydrophobicity in the context of folded proteins: A crystallographic hydration scale Protein Engineering, Design and Selection. 6: 129. DOI: 10.1093/Protein/6.Supplement.129-A |
0.456 |
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| 1993 |
Tainer J, Parge H, Borgstahl G, Fisher C, Redford S, Murtari D, Hickey M, McRae D, Hallewell R, Getzoff E. Cu, Zn and Mn superoxide dismutaes: Crystal structures, mutants, and function Free Radical Biology and Medicine. 15: 476. DOI: 10.1016/0891-5849(93)90205-9 |
0.474 |
|
| 1993 |
Tainer JA, Parge HE, Borgstahl GE, Fisher CL, Redford SM, Murtari DJ, Hickey MJ, McRee DE, Hallewell RA, Getzoff ED. Cu, Zn and Mn superoxide dismutases; Crystal structures, mutants, and function Journal of Inorganic Biochemistry. 51: 57. DOI: 10.1016/0162-0134(93)85093-N |
0.475 |
|
| 1992 |
Kuhn LA, Siani MA, Pique ME, Fisher CL, Getzoff ED, Tainer JA. The interdependence of protein surface topography and bound water molecules revealed by surface accessibility and fractal density measures Journal of Molecular Biology. 228: 13-22. PMID 1447777 DOI: 10.1016/0022-2836(92)90487-5 |
0.482 |
|
| 1992 |
Kuo CF, McRee DE, Fisher CL, O'Handley SF, Cunningham RP, Tainer JA. Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III Science. 258: 434-440. PMID 1411536 DOI: 10.1126/science.1411536 |
0.389 |
|
| 1992 |
Alexander H, Alexander S, Getzoff ED, Tainer JA, Geysen HM, Lerner RA. Altering the antigenicity of proteins Proceedings of the National Academy of Sciences of the United States of America. 89: 3352-3356. PMID 1373498 DOI: 10.1073/Pnas.89.8.3352 |
0.521 |
|
| 1992 |
Tainer JA, Roberts VA, Getzoff ED. Protein metal-binding sites Current Opinion in Biotechnology. 3: 378-387. PMID 1368439 DOI: 10.1016/0960-9822(92)90035-9 |
0.506 |
|
| 1991 |
Hallewell RA, Imlay KC, Lee P, Fong NM, Gallegos C, Getzoff ED, Tainer JA, Cabelli DE, Tekamp-Olson P, Mullenbach GT, Cousens LS. Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines Biochemical and Biophysical Research Communications. 181: 474-480. PMID 1958215 DOI: 10.1016/S0006-291X(05)81443-3 |
0.54 |
|
| 1991 |
Tainer JA, Deal CD, Geysen HM, Roberts VA, Getzoff ED. Defining antibody-antigen recognition: Towards engineered antibodies and epitopes International Reviews of Immunology. 7: 165-194. PMID 1721650 DOI: 10.3109/08830189109061773 |
0.409 |
|
| 1991 |
Alexander H, Alexander S, Heffron F, Fieser TM, Hay BN, Getzoff ED, Tainer JA, Lerner RA. Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene Gene. 99: 151-156. PMID 1708739 DOI: 10.1016/0378-1119(91)90121-Q |
0.51 |
|
| 1991 |
Fisher CL, Hallewell RA, Roberts VA, Tainer JA, Getzoff ED. Probing the structural basis for enzyme-substrate recognition in cu, zn superoxide dismutase Free Radical Research. 12: 287-296. PMID 1649096 DOI: 10.3109/10715769109145797 |
0.558 |
|
| 1991 |
Roberts VA, Fisher CL, Redford SM, Mcree DE, Parge HE, Getzoff ED, Tainer JA. Mechanism and atomic structure of superoxide dismutase Free Radical Research. 12: 269-278. PMID 1649094 DOI: 10.3109/10715769109145795 |
0.51 |
|
| 1991 |
Tainer JA, Roberts VA, Getzoff ED. Metal-binding sites in proteins Current Opinion in Biotechnology. 2: 582-591. PMID 1367679 DOI: 10.1016/0958-1669(91)90084-I |
0.53 |
|
| 1990 |
Roberts VA, Iverson BL, Iverson SA, Benkovic SJ, Lerner RA, Getzoff ED, Tainer JA. Antibody remodeling: a general solution to the design of a metal-coordination site in an antibody binding pocket. Proceedings of the National Academy of Sciences of the United States of America. 87: 6654-8. PMID 2395868 DOI: 10.1073/Pnas.87.17.6654 |
0.525 |
|
| 1990 |
McRee D, Redford SM, Getzoff ED, Lepock JR, Hallewell RA, Tainer JA. Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine Journal of Biological Chemistry. 265: 14234-14241. PMID 2387847 DOI: 10.2210/Pdb3Sod/Pdb |
0.556 |
|
| 1990 |
Redford SM, McRee DE, Getzoff ED, Steinman HM, Tainer JA. Crystallographic characterization of a Cu,Zn superoxide dismutase from Photobacterium leiognathi Journal of Molecular Biology. 212: 449-451. PMID 2325128 DOI: 10.1016/0022-2836(90)90323-E |
0.47 |
|
| 1990 |
Fisher CL, Tainer JA, Pique ME, Getzoff ED. Visualization of molecular flexibility and its effects on electrostatic recognition Journal of Molecular Graphics. 8: 125-132. PMID 2279008 DOI: 10.1016/0263-7855(90)80052-H |
0.486 |
|
| 1989 |
Getzoff ED, Tainer JA, Stempien MM, Bell GI, Hallewell RA. Evolution of CuZn superoxide dismutase and the Greek key β-barrel structural motif Proteins: Structure, Function and Genetics. 5: 322-336. PMID 2798409 DOI: 10.1002/Prot.340050408 |
0.545 |
|
| 1989 |
McRee DE, Tainer JA, Meyer TE, Van Beeumen J, Cusanovich MA, Getzoff ED. Crystallographic structure of a photoreceptor protein at 2.4 A resolution Proceedings of the National Academy of Sciences of the United States of America. 86: 6533-6537. PMID 2771940 DOI: 10.1073/Pnas.86.17.6533 |
0.53 |
|
| 1988 |
Tainer JA, Hallewell RA, Roberts VA, Parge HE, Getzoff ED. Probing enzyme-substrate recognition and catalytic mechanism in Cu,Zn superoxide dismutase Basic Life Sciences. 49: 635-640. PMID 3250519 DOI: 10.1007/978-1-4684-5568-7_100 |
0.499 |
|
| 1988 |
Getzoff ED, Tainer JA, Lerner RA, Geysen HM. The chemistry and mechanism of antibody binding to protein antigens Advances in Immunology. 43: 1-98. PMID 3055852 DOI: 10.1016/S0065-2776(08)60363-6 |
0.514 |
|
| 1988 |
Getzoff ED, Parge HE, McRee DE, Tainer JA. Understanding the structure and antigenicity of gonococcal pili Reviews of Infectious Diseases. 10: S296-299. PMID 2903537 DOI: 10.1093/Cid/10.Supplement_2.S296 |
0.518 |
|
| 1987 |
Getzoff ED, Geysen HM, Rodda SJ, Alexander H, Tainer JA, Lerner RA. Mechanisms of antibody binding to a protein Science. 235: 1191-1196. PMID 3823879 DOI: 10.1126/Science.3823879 |
0.576 |
|
| 1987 |
Geysen HM, Tainer JA, Rodda SJ, Mason TJ, Alexander H, Getzoff ED, Lerner RA. Chemistry of antibody binding to a protein Science. 235: 1184-1190. PMID 3823878 DOI: 10.1126/Science.3823878 |
0.552 |
|
| 1987 |
Parge HE, McRee DE, Capozza MA, Bernstein SL, Getzoff ED, Tainer JA. Three dimensional structure of bacterial pili Antonie Van Leeuwenhoek. 53: 447-453. PMID 2897188 DOI: 10.1007/Bf00415501 |
0.544 |
|
| 1987 |
GEYSEN HM, RODDA SJ, MASON TJ, TAINER JA, ALEXANDER H, GETZOFF ED, LERNER RA. Response: Antigenicity of Myohemerythrin Science. 238: 1584-1586. DOI: 10.1126/Science.238.4833.1584-A |
0.399 |
|
| 1986 |
Getzoff ED, Tainer JA, Olson AJ. Recognition and interactions controlling the assemblies of beta barrel domains Biophysical Journal. 49: 191-206. PMID 3955170 DOI: 10.1016/S0006-3495(86)83634-7 |
0.679 |
|
| 1986 |
Hazzard JT, Cusanovich MA, Tainer JA, Getzoff ED, Tollin G. Kinetic studies of reduction of a 1:1 cytochrome c-flavodoxin complex by free flavin semiquinones and rubredoxin Biochemistry. 25: 3318-3328. PMID 3015203 DOI: 10.1021/Bi00359A035 |
0.477 |
|
| 1985 |
Tainer JA, Getzoff ED, Paterson Y, Olson AJ, Lerner RA. The atomic mobility component of protein antigenicity Annual Review of Immunology. 3: 501-535. PMID 2415142 DOI: 10.1146/Annurev.Iy.03.040185.002441 |
0.651 |
|
| 1985 |
So M, Billyard E, Deal C, Getzoff E, Hagblom P, Meyer TF, Segal E, Tainer J. Gonococcal pilus: genetics and structure. Current Topics in Microbiology and Immunology. 118: 13-28. PMID 2414068 DOI: 10.1007/978-3-642-70586-1_2 |
0.531 |
|
| 1985 |
Wilson IA, Haft DH, Getzoff ED, Tainer JA, Lerner RA, Brenner S. Identical short peptide sequences in unrelated proteins can have different conformations: A testing ground for theories of immune recognition Proceedings of the National Academy of Sciences of the United States of America. 82: 5255-5259. PMID 2410917 DOI: 10.1073/Pnas.82.16.5255 |
0.482 |
|
| 1984 |
Tainer JA, Getzoff ED, Alexander H, Houghten RA, Olson AJ, Lerner RA, Hendrickson WA. The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein Nature. 312: 127-134. PMID 6209578 DOI: 10.1038/312127A0 |
0.62 |
|
| 1983 |
Getzoff ED, Tainer JA, Weiner PK, Kollman PA, Richardson JS, Richardson DC. Electrostatic recognition between superoxide and copper, zinc superoxide dismutase. Nature. 306: 287-90. PMID 6646211 DOI: 10.1038/306287A0 |
0.718 |
|
| 1983 |
Tainer JA, Getzoff ED, Richardson JS, Richardson DC. Structure and mechanism of copper, zinc superoxide dismutase. Nature. 306: 284-7. PMID 6316150 DOI: 10.1038/306284A0 |
0.703 |
|
| 1982 |
Tainer JA, Getzoff ED, Beem KM, Richardson JS, Richardson DC. Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase. Journal of Molecular Biology. 160: 181-217. PMID 7175933 DOI: 10.1016/0022-2836(82)90174-7 |
0.698 |
|
| 1980 |
Richardson JS, Tainer JA, Richardson DC. An illustrated museum of protein structures. Biophysical Journal. 32: 211-3. PMID 19431356 DOI: 10.1016/S0006-3495(80)84934-4 |
0.613 |
|
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