| Year |
Citation |
Score |
| 2020 |
Sullivan SA, Nawarathne I, Walker KD. CoA recycling by a benzoate coenzyme a ligase in cascade reactions with aroyltransferases to biocatalyze paclitaxel analogs. Archives of Biochemistry and Biophysics. 108276. PMID 31978400 DOI: 10.1016/J.Abb.2020.108276 |
0.786 |
|
| 2019 |
Shee PK, Ratnayake ND, Walter T, Goethe O, Onyeozili EN, Walker KD. Exploring the Scope of an α/β-Aminomutase for the Amination of Cinnamate Epoxides to Arylserines and Arylisoserines Acs Catalysis. 9: 7418-7430. DOI: 10.1021/Acscatal.9B01557 |
0.412 |
|
| 2018 |
Attanayake G, Walter T, Walker KD. Understanding Which Residues of the Active Site and Loop Structure of a Tyrosine Aminomutase Define its Mutase and Lyase Activities. Biochemistry. PMID 29757631 DOI: 10.1021/Acs.Biochem.8B00269 |
0.384 |
|
| 2017 |
Thornburg CK, Walter T, Walker KD. Biocatalysis of a Paclitaxel Analogue: Conversion of Baccatin III to N-Debenzoyl-N-(2-furoyl)paclitaxel and Characterization of an Amino Phenylpropanoyl CoA Transferase. Biochemistry. PMID 29068219 DOI: 10.1021/Acs.Biochem.7B00912 |
0.496 |
|
| 2017 |
Muchiri R, Walker KD. Paclitaxel Biosynthesis: Adenylation and Thiolation Domains of an NRPS TycA PheAT Module Produce Various Arylisoserine CoA Thioesters. Biochemistry. PMID 28230972 DOI: 10.1021/Acs.Biochem.6B01188 |
0.395 |
|
| 2016 |
Sa N, Rawat R, Thornburg C, Walker KD, Roje S. Identification and characterization of the missing phosphatase on the riboflavin biosynthesis pathway in Arabidopsis thaliana. The Plant Journal : For Cell and Molecular Biology. PMID 27490826 DOI: 10.1111/Tpj.13291 |
0.365 |
|
| 2016 |
Walter T, Wijewardena D, Walker KD. Mutation of Aryl Binding-Pocket Residues Results in an Unexpected Activity Switch in an Oryza sativa Tyrosine Aminomutase. Biochemistry. PMID 27243642 DOI: 10.1021/Acs.Biochem.6B00331 |
0.366 |
|
| 2015 |
Walter T, King Z, Walker KD. A Tyrosine Aminomutase from Rice (Oryza sativa) Isomerizes (S)-α- to (R)-β-Tyrosine with Unique High Enantioselectivity and Retention of Configuration. Biochemistry. PMID 26709535 DOI: 10.1021/Acs.Biochem.5B01331 |
0.329 |
|
| 2015 |
Ratnayake ND, Theisen C, Walter T, Walker KD. Whole-Cell Biocatalytic Production of Variously Substituted β-Aryl- and β-Heteroaryl-β-Amino Acids. Journal of Biotechnology. PMID 26528624 DOI: 10.1016/J.Jbiotec.2015.10.012 |
0.318 |
|
| 2015 |
Thornburg CK, Wortas-Strom S, Nosrati M, Geiger JH, Walker KD. Kinetically and Crystallographically Guided Mutations of a Benzoate CoA Ligase (BadA) Elucidate Mechanism and Expand Substrate Permissivity. Biochemistry. 54: 6230-42. PMID 26378464 DOI: 10.1021/Acs.Biochem.5B00899 |
0.433 |
|
| 2014 |
Ratnayake ND, Liu N, Kuhn LA, Walker KD. Ring-substituted α-arylalanines for probing substituent effects on the isomerization reaction catalyzed by an aminomutase Acs Catalysis. 4: 3077-3090. DOI: 10.1021/Cs500474S |
0.428 |
|
| 2013 |
Wanninayake U, Walker KD. A bacterial tyrosine aminomutase proceeds through retention or inversion of stereochemistry to catalyze its isomerization reaction. Journal of the American Chemical Society. 135: 11193-204. PMID 23800193 DOI: 10.1021/Ja403918W |
0.785 |
|
| 2012 |
Muchiri R, Walker KD. Taxol biosynthesis: tyrocidine synthetase A catalyzes the production of phenylisoserinyl CoA and other amino phenylpropanoyl thioesters. Chemistry & Biology. 19: 679-85. PMID 22726682 DOI: 10.1016/J.Chembiol.2012.05.007 |
0.369 |
|
| 2012 |
Wanninayake U, Walker KD. Assessing the deamination rate of a covalent aminomutase adduct by burst phase analysis. Biochemistry. 51: 5226-8. PMID 22686417 DOI: 10.1021/Bi300569R |
0.772 |
|
| 2012 |
Strom S, Wanninayake U, Ratnayake ND, Walker KD, Geiger JH. Insights into the mechanistic pathway of the Pantoea agglomerans phenylalanine aminomutase. Angewandte Chemie (International Ed. in English). 51: 2898-902. PMID 22319000 DOI: 10.1002/Anie.201108525 |
0.804 |
|
| 2011 |
Wanninayake U, Deporre Y, Ondari M, Walker KD. (S)-Styryl-α-alanine used to probe the intermolecular mechanism of an intramolecular MIO-aminomutase. Biochemistry. 50: 10082-90. PMID 21985059 DOI: 10.1021/Bi2012299 |
0.748 |
|
| 2011 |
Ratnayake ND, Wanninayake U, Geiger JH, Walker KD. Stereochemistry and mechanism of a microbial phenylalanine aminomutase. Journal of the American Chemical Society. 133: 8531-3. PMID 21561099 DOI: 10.1021/Ja2030728 |
0.779 |
|
| 2011 |
Feng L, Wanninayake U, Strom S, Geiger J, Walker KD. Mechanistic, mutational, and structural evaluation of a Taxus phenylalanine aminomutase. Biochemistry. 50: 2919-30. PMID 21361343 DOI: 10.1021/Bi102067R |
0.79 |
|
| 2010 |
Wijeratne S, Byrne NA, Walker KD. Separation of alpha- from beta-arylalanines by nickel nitrilotriacetate chromatography. Journal of Separation Science. 33: 1279-82. PMID 20201044 DOI: 10.1002/Jssc.200900675 |
0.324 |
|
| 2010 |
Nawarathne IN, Walker KD. Point mutations (Q19P and N23K) increase the operational solubility of a 2alpha-O-benzoyltransferase that conveys various acyl groups from CoA to a taxane acceptor. Journal of Natural Products. 73: 151-9. PMID 20108947 DOI: 10.1021/Np900524D |
0.759 |
|
| 2009 |
Cox BM, Bilsborrow JB, Walker KD. Enhanced conversion of racemic alpha-arylalanines to (R)-beta-arylalanines by coupled racemase/aminomutase catalysis. The Journal of Organic Chemistry. 74: 6953-9. PMID 19711925 DOI: 10.1021/Jo9009563 |
0.381 |
|
| 2009 |
Nevarez DM, Mengistu YA, Nawarathne IN, Walker KD. An N-aroyltransferase of the BAHD superfamily has broad aroyl CoA specificity in vitro with analogues of N-dearoylpaclitaxel. Journal of the American Chemical Society. 131: 5994-6002. PMID 19382815 DOI: 10.1021/Ja900545M |
0.639 |
|
| 2009 |
Ondari ME, Walker KD. Synthesis of 4-deacetyl-1-dimethylsilyl-7-triethylsilylbaccatin III. The Journal of Organic Chemistry. 74: 2186-8. PMID 19199654 DOI: 10.1021/Jo802598M |
0.759 |
|
| 2008 |
Ondari ME, Walker KD. The taxol pathway 10-O-acetyltransferase shows regioselective promiscuity with the oxetane hydroxyl of 4-deacetyltaxanes. Journal of the American Chemical Society. 130: 17187-94. PMID 19007225 DOI: 10.1021/Ja8067534 |
0.775 |
|
| 2007 |
Mutatu W, Klettke KL, Foster C, Walker KD. Unusual mechanism for an aminomutase rearrangement: retention of configuration at the migration termini. Biochemistry. 46: 9785-94. PMID 17676876 DOI: 10.1021/Bi700691P |
0.769 |
|
| 2007 |
Klettke KL, Sanyal S, Mutatu W, Walker KD. Beta-styryl- and beta-aryl-beta-alanine products of phenylalanine aminomutase catalysis. Journal of the American Chemical Society. 129: 6988-9. PMID 17500524 DOI: 10.1021/Ja071328W |
0.759 |
|
| 2007 |
Loncaric C, Ward AF, Walker KD. Expression of an acetyl-CoA synthase and a CoA-transferase in Escherichia coli to produce modified taxanes in vivo. Biotechnology Journal. 2: 266-74. PMID 17183509 DOI: 10.1002/Biot.200600194 |
0.425 |
|
| 2006 |
Loncaric C, Merriweather E, Walker KD. Profiling a Taxol pathway 10beta-acetyltransferase: assessment of the specificity and the production of baccatin III by in vivo acetylation in E. coli. Chemistry & Biology. 13: 309-17. PMID 16638536 DOI: 10.1016/J.Chembiol.2006.01.006 |
0.476 |
|
| 2004 |
Walker KD, Klettke K, Akiyama T, Croteau R. Cloning, heterologous expression, and characterization of a phenylalanine aminomutase involved in Taxol biosynthesis. The Journal of Biological Chemistry. 279: 53947-54. PMID 15494399 DOI: 10.1074/Jbc.M411215200 |
0.422 |
|
| 2004 |
Chau M, Walker K, Long R, Croteau R. Regioselectivity of taxoid-O-acetyltransferases: heterologous expression and characterization of a new taxadien-5alpha-ol-O-acetyltransferase. Archives of Biochemistry and Biophysics. 430: 237-46. PMID 15369823 DOI: 10.1016/J.Abb.2004.07.013 |
0.407 |
|
| 2004 |
Jennewein S, Wildung MR, Chau M, Walker K, Croteau R. Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 9149-54. PMID 15178753 DOI: 10.1073/Pnas.0403009101 |
0.326 |
|
| 2004 |
Chau M, Jennewein S, Walker K, Croteau R. Taxol biosynthesis: Molecular cloning and characterization of a cytochrome P450 taxoid 7 beta-hydroxylase. Chemistry & Biology. 11: 663-72. PMID 15157877 DOI: 10.1016/J.Chembiol.2004.02.025 |
0.347 |
|
| 2002 |
Walker K, Fujisaki S, Long R, Croteau R. Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 12715-20. PMID 12232048 DOI: 10.1073/Pnas.192463699 |
0.473 |
|
| 2002 |
Walker K, Long R, Croteau R. The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus. Proceedings of the National Academy of Sciences of the United States of America. 99: 9166-71. PMID 12089320 DOI: 10.1073/Pnas.082115799 |
0.491 |
|
| 2001 |
Walker K, Croteau R. Taxol biosynthetic genes Phytochemistry. 58: 1-7. PMID 11524108 DOI: 10.1016/S0031-9422(01)00160-1 |
0.374 |
|
| 2000 |
Walker K, Croteau R. Taxol biosynthesis: Molecular cloning of a benzoyl-CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 97: 13591-13596. PMID 11095755 DOI: 10.1073/Pnas.250491997 |
0.422 |
|
| 2000 |
Walker K, Schoendorf A, Croteau R. Molecular cloning of a taxa-4(20),11(12)-dien-5α-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli Archives of Biochemistry and Biophysics. 374: 371-380. PMID 10666320 DOI: 10.1006/Abbi.1999.1609 |
0.433 |
|
| 2000 |
Walker K, Croteau R. Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 97: 583-587. PMID 10639122 DOI: 10.1073/Pnas.97.2.583 |
0.415 |
|
| 1999 |
Walker K, Ketchum RE, Hezari M, Gatfield D, Goleniowski M, Barthol A, Croteau R. Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis. Archives of Biochemistry and Biophysics. 364: 273-9. PMID 10190984 DOI: 10.1006/Abbi.1999.1125 |
0.418 |
|
| 1996 |
Chesters NCJE, Walker K, O'Hagan D, Floss HG. The biosynthesis of tropic acid: A reevaluation of the stereochemical course of the conversion of phenyllactate to tropate in Datura stramonium Journal of the American Chemical Society. 118: 925-926. DOI: 10.1021/Ja9531485 |
0.316 |
|
| 1994 |
Fleming PE, Floss HG, Haertel M, Knaggs AR, Lansing A, Mocek U, Walker KD. Biosynthetic studies on taxol Pure and Applied Chemistry. 66: 2045-2048. DOI: 10.1351/Pac199466102045 |
0.35 |
|
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