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Indraneel Ghosh, Ph.D. - Publications

Affiliations: 
2001- Chemistry University of Arizona, Tucson, AZ 
Area:
Bioorganic Chemistry
Website:
http://www.chem.arizona.edu/faculty_profile/ghos/group.dir/index.html
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67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Castillo-Montoya J, Ghosh I. Engineering Small Molecule Responsive Split Protein Kinases. Methods in Molecular Biology (Clifton, N.J.). 1596: 307-319. PMID 28293895 DOI: 10.1007/978-1-4939-6940-1_19  0.831
2015 Campbell ST, Carlson KJ, Buchholz CJ, Helmers MR, Ghosh I. Mapping the BH3 Binding Interface of Bcl-xL, Bcl-2, and Mcl-1 Using Split-Luciferase Reassembly. Biochemistry. 54: 2632-43. PMID 25844633 DOI: 10.1021/Bi501505Y  0.779
2015 Restituyo E, Camacho-Soto K, Ghosh I. A fragment-based selection approach for the discovery of peptide macrocycles targeting protein kinases. Methods in Molecular Biology (Clifton, N.J.). 1248: 95-104. PMID 25616328 DOI: 10.1007/978-1-4939-2020-4_7  0.826
2014 Camacho-Soto K, Castillo-Montoya J, Tye B, Ogunleye LO, Ghosh I. Small molecule gated split-tyrosine phosphatases and orthogonal split-tyrosine kinases. Journal of the American Chemical Society. 136: 17078-86. PMID 25409264 DOI: 10.1021/Ja5080745  0.77
2014 Camacho-Soto K, Castillo-Montoya J, Tye B, Ghosh I. Ligand-gated split-kinases. Journal of the American Chemical Society. 136: 3995-4002. PMID 24533431 DOI: 10.1021/Ja4130803  0.798
2014 Ogunleye LO, Jester BW, Riemen AJ, Badran AH, Wang P, Ghosh I. When tight is too tight: Dasatinib and its lower affinity analogue for profiling kinase inhibitors in a three-hybrid split-luciferase system Medchemcomm. 5: 328-332. DOI: 10.1039/C3Md00275F  0.808
2012 Sarma U, Ghosh I. Different designs of kinase-phosphatase interactions and phosphatase sequestration shapes the robustness and signal flow in the MAPK cascade. Bmc Systems Biology. 6: 82. PMID 22748295 DOI: 10.1186/1752-0509-6-82  0.326
2012 Lamba V, Ghosh I. New directions in targeting protein kinases: focusing upon true allosteric and bivalent inhibitors. Current Pharmaceutical Design. 18: 2936-45. PMID 22571662 DOI: 10.2174/138161212800672813  0.844
2012 Jester BW, Gaj A, Shomin CD, Cox KJ, Ghosh I. Testing the promiscuity of commercial kinase inhibitors against the AGC kinase group using a split-luciferase screen. Journal of Medicinal Chemistry. 55: 1526-37. PMID 22257127 DOI: 10.1021/Jm201265F  0.817
2011 Shekhawat SS, Ghosh I. Split-protein systems: beyond binary protein-protein interactions. Current Opinion in Chemical Biology. 15: 789-97. PMID 22070901 DOI: 10.1016/J.Cbpa.2011.10.014  0.758
2011 Shomin CD, Restituyo E, Cox KJ, Ghosh I. Selection of cyclic-peptide inhibitors targeting Aurora kinase A: problems and solutions. Bioorganic & Medicinal Chemistry. 19: 6743-9. PMID 22004849 DOI: 10.1016/J.Bmc.2011.09.049  0.806
2011 Shekhawat SS, Campbell ST, Ghosh I. A comprehensive panel of turn-on caspase biosensors for investigating caspase specificity and caspase activation pathways. Chembiochem : a European Journal of Chemical Biology. 12: 2353-64. PMID 21850719 DOI: 10.1002/Cbic.201100372  0.772
2011 Badran AH, Furman JL, Ma AS, Comi TJ, Porter JR, Ghosh I. Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor. Analytical Chemistry. 83: 7151-7. PMID 21797230 DOI: 10.1021/Ac2015239  0.777
2011 Furman JL, Mok PW, Badran AH, Ghosh I. Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA. Journal of the American Chemical Society. 133: 12518-27. PMID 21520929 DOI: 10.1021/Ja1116606  0.782
2011 Cox KJ, Shomin CD, Ghosh I. Tinkering outside the kinase ATP box: allosteric (type IV) and bivalent (type V) inhibitors of protein kinases. Future Medicinal Chemistry. 3: 29-43. PMID 21428824 DOI: 10.4155/Fmc.10.272  0.834
2011 Furman JL, Mok PW, Shen S, Stains CI, Ghosh I. A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death. Chemical Communications (Cambridge, England). 47: 397-9. PMID 20830433 DOI: 10.1039/C0Cc02229B  0.763
2010 Porter JR, Helmers MR, Wang P, Furman JL, Joy ST, Arora PS, Ghosh I. Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2. Chemical Communications (Cambridge, England). 46: 8020-2. PMID 20856941 DOI: 10.1039/C0Cc02969F  0.802
2010 Henchey LK, Porter JR, Ghosh I, Arora PS. High specificity in protein recognition by hydrogen-bond-surrogate α-helices: selective inhibition of the p53/MDM2 complex. Chembiochem : a European Journal of Chemical Biology. 11: 2104-7. PMID 20821791 DOI: 10.1002/Cbic.201000378  0.58
2010 Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Toward a general approach for RNA-templated hierarchical assembly of split-proteins. Journal of the American Chemical Society. 132: 11692-701. PMID 20681585 DOI: 10.1021/Ja104395B  0.799
2010 Stains CI, Furman JL, Porter JR, Rajagopal S, Li Y, Wyatt RT, Ghosh I. A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. Acs Chemical Biology. 5: 943-52. PMID 20681584 DOI: 10.1021/Cb100143M  0.795
2010 Porter JR, Lockwood SH, Segal DJ, Ghosh I. Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER). Methods in Molecular Biology (Clifton, N.J.). 649: 365-82. PMID 20680847 DOI: 10.1007/978-1-60761-753-2_23  0.546
2010 Jester BW, Cox KJ, Gaj A, Shomin CD, Porter JR, Ghosh I. A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases. Journal of the American Chemical Society. 132: 11727-35. PMID 20669947 DOI: 10.1021/Ja104491H  0.826
2010 Yu Y, Blair S, Gillespie D, Jensen R, Myszka D, Badran AH, Ghosh I, Chagovetz A. Direct DNA methylation profiling using methyl binding domain proteins. Analytical Chemistry. 82: 5012-9. PMID 20507169 DOI: 10.1021/Ac1010316  0.663
2010 Meyer SC, Ghosh I. Phage display technology in biosensor development Recognition Receptors in Biosensors. 723-749. DOI: 10.1007/978-1-4419-0919-0_18  0.462
2009 Shekhawat SS, Porter JR, Sriprasad A, Ghosh I. An autoinhibited coiled-coil design strategy for split-protein protease sensors. Journal of the American Chemical Society. 131: 15284-90. PMID 19803505 DOI: 10.1021/Ja9050857  0.779
2009 Shomin CD, Meyer SC, Ghosh I. Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling. Bioorganic & Medicinal Chemistry. 17: 6196-202. PMID 19674907 DOI: 10.1016/J.Bmc.2009.07.056  0.849
2009 Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA. Bioorganic & Medicinal Chemistry Letters. 19: 3748-51. PMID 19457665 DOI: 10.1016/J.Bmcl.2009.04.141  0.795
2009 Deng Z, Lie FL, Shen S, Ghosh I, Mansuripur M, Muscat AJ. Water-based route to ligand-selective synthesis of ZnSe and Cd-doped ZnSe quantum dots with tunable ultraviolet A to blue photoluminescence. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 434-42. PMID 19053829 DOI: 10.1021/La802294E  0.745
2008 Porter JR, Stains CI, Jester BW, Ghosh I. A general and rapid cell-free approach for the interrogation of protein-protein, protein-DNA, and protein-RNA interactions and their antagonists utilizing split-protein reporters. Journal of the American Chemical Society. 130: 6488-97. PMID 18444624 DOI: 10.1021/Ja7114579  0.803
2007 Stains CI, Mondal K, Ghosh I. Molecules that target beta-amyloid. Chemmedchem. 2: 1674-92. PMID 17952881 DOI: 10.1002/Cmdc.200700140  0.713
2007 Meyer SC, Shomin CD, Gaj T, Ghosh I. Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A. Journal of the American Chemical Society. 129: 13812-3. PMID 17944472 DOI: 10.1021/Ja076197D  0.846
2007 Stains CI, Ghosh I. When conjugated polymers meet amyloid fibrils. Acs Chemical Biology. 2: 525-8. PMID 17708668 DOI: 10.1021/Cb700165V  0.673
2007 Gaj T, Meyer SC, Ghosh I. The AviD-tag, a NeutrAvidin/avidin specific peptide affinity tag for the immobilization and purification of recombinant proteins. Protein Expression and Purification. 56: 54-61. PMID 17697784 DOI: 10.1016/J.Pep.2007.06.010  0.805
2007 Porter JR, Stains CI, Segal DJ, Ghosh I. Split beta-lactamase sensor for the sequence-specific detection of DNA methylation. Analytical Chemistry. 79: 6702-8. PMID 17685552 DOI: 10.1021/Ac071163+  0.762
2007 Zhou M, Nakatani E, Gronenberg LS, Tokimoto T, Wirth MJ, Hruby VJ, Roberts A, Lynch RM, Ghosh I. Peptide-labeled quantum dots for imaging GPCRs in whole cells and as single molecules. Bioconjugate Chemistry. 18: 323-32. PMID 17373766 DOI: 10.1021/Bc0601929  0.766
2007 Tokimoto T, Bethea TR, Zhou M, Ghosh I, Wirth MJ. Probing orientations of single fluorescent labels on a peptide reversibly binding to the human delta-opioid receptor. Applied Spectroscopy. 61: 130-7. PMID 17331303 DOI: 10.1366/000370207779947512  0.398
2007 Zhou M, Ghosh I. Quantum dots and peptides: a bright future together. Biopolymers. 88: 325-39. PMID 17167795 DOI: 10.1002/Bip.20655  0.427
2006 Ghosh I, Stains CI, Ooi AT, Segal DJ. Direct detection of double-stranded DNA: Molecular methods and applications for DNA diagnostics. Molecular Biosystems. 2: 551-60. PMID 17216036 DOI: 10.1039/B611169F  0.713
2006 Smith TJ, Stains CI, Meyer SC, Ghosh I. Inhibition of beta-amyloid fibrillization by directed evolution of a beta-sheet presenting miniature protein. Journal of the American Chemical Society. 128: 14456-7. PMID 17090018 DOI: 10.1021/Ja065557E  0.756
2006 Rajagopal S, Meyer SC, Goldman A, Zhou M, Ghosh I. A minimalist approach toward protein recognition by epitope transfer from functionally evolved beta-sheet surfaces. Journal of the American Chemical Society. 128: 14356-63. PMID 17076509 DOI: 10.1021/Ja064885B  0.8
2006 Meyer SC, Gaj T, Ghosh I. Highly selective cyclic peptide ligands for NeutrAvidin and avidin identified by phage display. Chemical Biology & Drug Design. 68: 3-10. PMID 16923020 DOI: 10.1111/J.1747-0285.2006.00401.X  0.796
2006 Stains CI, Furman JL, Segal DJ, Ghosh I. Site-specific detection of DNA methylation utilizing mCpG-SEER. Journal of the American Chemical Society. 128: 9761-5. PMID 16866532 DOI: 10.1021/Ja060681J  0.798
2006 Ooi AT, Stains CI, Ghosh I, Segal DJ. Sequence-enabled reassembly of beta-lactamase (SEER-LAC): a sensitive method for the detection of double-stranded DNA. Biochemistry. 45: 3620-5. PMID 16533044 DOI: 10.1021/Bi0517032  0.722
2006 Ooi AT, Stains CI, Ghosh I, Segal DJ. 973. SEquence-Enabled Reassembly of β- Lactamase (SEER-LAC): A Sensitive Method for the Detection of Double-Stranded DNA Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1065  0.365
2005 Stains CI, Porter JR, Ooi AT, Segal DJ, Ghosh I. DNA sequence-enabled reassembly of the green fluorescent protein. Journal of the American Chemical Society. 127: 10782-3. PMID 16076155 DOI: 10.1021/Ja051969W  0.781
2005 Meyer SC, Huerta C, Ghosh I. Single-site mutations in a hyperthermophilic variant of the B1 domain of protein G result in self-assembled oligomers. Biochemistry. 44: 2360-8. PMID 15709748 DOI: 10.1021/Bi048197L  0.578
2005 Magliery TJ, Wilson CG, Pan W, Mishler D, Ghosh I, Hamilton AD, Regan L. Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: scope and mechanism. Journal of the American Chemical Society. 127: 146-57. PMID 15631464 DOI: 10.1021/Ja046699G  0.775
2004 Ghosh I, Chmielewski J. Peptide self-assembly as a model of proteins in the pre-genomic world. Current Opinion in Chemical Biology. 8: 640-4. PMID 15556409 DOI: 10.1016/J.Cbpa.2004.09.001  0.708
2004 Zhou M, Ghosh I. Noncovalent multivalent assembly of jun peptides on a leucine zipper dendrimer displaying fos peptides. Organic Letters. 6: 3561-4. PMID 15387548 DOI: 10.1021/Ol0485262  0.454
2004 Reiner O, Gdalyahu A, Ghosh I, Levy T, Sapoznik S, Nir R, Sapir T. DCX's phosphorylation by not just another kinase (JNK). Cell Cycle (Georgetown, Tex.). 3: 747-51. PMID 15118415 DOI: 10.4161/Cc.3.6.909  0.392
2004 Rajagopal S, Meza-Romero R, Ghosh I. Dual surface selection methodology for the identification of thrombin binding epitopes from hotspot biased phage-display libraries. Bioorganic & Medicinal Chemistry Letters. 14: 1389-93. PMID 15006368 DOI: 10.1016/J.Bmcl.2003.09.098  0.595
2004 Gdalyahu A, Ghosh I, Levy T, Sapir T, Sapoznik S, Fishler Y, Azoulai D, Reiner O. DCX, a new mediator of the JNK pathway. The Embo Journal. 23: 823-32. PMID 14765123 DOI: 10.1038/Sj.Emboj.7600079  0.315
2004 Zhou M, Bentley D, Ghosh I. Helical supramolecules and fibers utilizing leucine zipper-displaying dendrimers. Journal of the American Chemical Society. 126: 734-5. PMID 14733545 DOI: 10.1021/Ja036634Y  0.375
2001 Ghosh I, Bishop P, Chmielewski J. DNA binding properties of basic helix-loop-helix fusion proteins of Tal and E47 Journal of Peptide Research. 57: 354-360. PMID 11350595 DOI: 10.1034/J.1399-3011.2001.00846.X  0.793
2000 Ghosh I, Hamilton AD, Regan L. Antiparallel leucine zipper-directed protein reassembly: Application to the green fluorescent protein [12] Journal of the American Chemical Society. 122: 5658-5659. DOI: 10.1021/Ja994421W  0.569
1999 Ma Y, Cunningham ME, Wang X, Ghosh I, Regan L, Longley BJ. Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region. The Journal of Biological Chemistry. 274: 13399-402. PMID 10224103 DOI: 10.1074/Jbc.274.19.13399  0.571
1999 Ghosh I, Issac R, Chmielewski J. Structure-function relationship in a β-sheet peptide Inhibitor of E47 dimerization and DNA binding Bioorganic and Medicinal Chemistry. 7: 61-66. PMID 10199656 DOI: 10.1016/S0968-0896(98)00214-4  0.79
1999 Yao S, Ghosh I, Zutshi R, Chmielewski J. A pH-Modulated, Self-Replicating Peptide [J. Am.Chem. Soc.1997,119, 10559−10560]. Journal of the American Chemical Society. 121: 8132-8132. DOI: 10.1021/Ja995525+  0.771
1998 Yao S, Ghosh I, Zutshi R, Chmielewski J. A Self-Replicating Peptide under Ionic Control. Angewandte Chemie (International Ed. in English). 37: 478-481. PMID 29711158 DOI: 10.1002/(Sici)1521-3773(19980302)37:4<478::Aid-Anie478>3.0.Co;2-V  0.774
1998 Yao S, Ghosh I, Zutshi R, Chmielewski J. Selective amplification by auto- and cross-catalysis in a replicating peptide system Nature. 396: 447-450. PMID 9853750 DOI: 10.1038/24814  0.789
1998 Ghosh I, Chmielewski J. A β-sheet peptide inhibitor of E47 dimerization and DNA binding Chemistry and Biology. 5: 439-445. PMID 9710566 DOI: 10.1016/S1074-5521(98)90160-0  0.714
1998 Yao S, Ghosh I, Zutshi R, Chmielewski J. Selbstreplikation eines Peptids unter Ionenkontrolle Angewandte Chemie. 110: 489-492. DOI: 10.1002/(Sici)1521-3757(19980216)110:4<489::Aid-Ange489>3.0.Co;2-K  0.774
1998 Yao S, Ghosh I, Zutshi R, Chmielewski J. A self-replicating peptide under ionic control Angewandte Chemie - International Edition in English. 37: 478-481.  0.671
1997 Yao S, Ghosh I, Zutshi R, Chmielewski J. A pH-modulated, self-replicating peptide Journal of the American Chemical Society. 119: 10559-10560. DOI: 10.1021/Ja9710619  0.771
1995 Bishop P, Jones C, Ghosh I, Chmielewski J. Synthesis of the basic-helix-loop-helix region of the immunoglobulin enhancer binding protein E47 and evaluation of its structural and DNA binding properties International Journal of Peptide and Protein Research. 46: 149-154. PMID 8567169 DOI: 10.1111/J.1399-3011.1995.Tb01330.X  0.793
1995 Bishop P, Ghosh I, Jones C, Chimielewski J. Correction. Basic-Helix-Loop-Helix Region of Tal: Evaluation of Structure and DNA Affinity Journal of the American Chemical Society. 117: 11616-11616. DOI: 10.1021/Ja00151A600  0.725
1995 Bishop P, Ghosh I, Jones C, Chmielewski J. Basic-helix-loop-helix region of tal: Evaluation of structure and DNA affinity Journal of the American Chemical Society. 117: 8283-8284. DOI: 10.1021/Ja00136A032  0.772
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