Year |
Citation |
Score |
2024 |
Hew BE, Gupta S, Sato R, Waller DF, Stoytchev I, Short JE, Sharek L, Tran CT, Badran AH, Owens JB. Directed evolution of hyperactive integrases for site specific insertion of transgenes. Nucleic Acids Research. PMID 38953167 DOI: 10.1093/nar/gkae534 |
0.318 |
|
2024 |
Hew BE, Gupta S, Sato R, Waller DF, Stoytchev I, Short JE, Sharek L, Tran CT, Badran AH, Owens JB. Directed evolution of hyperactive integrases for site specific insertion of transgenes. Biorxiv : the Preprint Server For Biology. PMID 38915697 DOI: 10.1101/2024.06.10.598370 |
0.318 |
|
2017 |
Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature. PMID 29160308 DOI: 10.1038/Nature24644 |
0.352 |
|
2017 |
Komor AC, Badran AH, Liu DR. Editing the Genome Without Double-Stranded DNA Breaks. Acs Chemical Biology. PMID 28957631 DOI: 10.1021/Acschembio.7B00710 |
0.311 |
|
2015 |
Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR. Continuous directed evolution of DNA-binding proteins to improve TALEN specificity. Nature Methods. 12: 939-42. PMID 26258293 DOI: 10.1038/Nmeth.3515 |
0.402 |
|
2014 |
Ogunleye LO, Jester BW, Riemen AJ, Badran AH, Wang P, Ghosh I. When tight is too tight: Dasatinib and its lower affinity analogue for profiling kinase inhibitors in a three-hybrid split-luciferase system Medchemcomm. 5: 328-332. DOI: 10.1039/C3Md00275F |
0.42 |
|
2011 |
Badran AH, Furman JL, Ma AS, Comi TJ, Porter JR, Ghosh I. Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor. Analytical Chemistry. 83: 7151-7. PMID 21797230 DOI: 10.1021/Ac2015239 |
0.538 |
|
2011 |
Furman JL, Mok PW, Badran AH, Ghosh I. Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA. Journal of the American Chemical Society. 133: 12518-27. PMID 21520929 DOI: 10.1021/Ja1116606 |
0.51 |
|
2010 |
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Toward a general approach for RNA-templated hierarchical assembly of split-proteins. Journal of the American Chemical Society. 132: 11692-701. PMID 20681585 DOI: 10.1021/Ja104395B |
0.455 |
|
2010 |
Yu Y, Blair S, Gillespie D, Jensen R, Myszka D, Badran AH, Ghosh I, Chagovetz A. Direct DNA methylation profiling using methyl binding domain proteins. Analytical Chemistry. 82: 5012-9. PMID 20507169 DOI: 10.1021/Ac1010316 |
0.525 |
|
2009 |
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA. Bioorganic & Medicinal Chemistry Letters. 19: 3748-51. PMID 19457665 DOI: 10.1016/J.Bmcl.2009.04.141 |
0.549 |
|
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