| Year |
Citation |
Score |
| 2024 |
Mojanaga OO, Woodman TJ, Lloyd MD, Acharya KR. α-Methylacyl-CoA Racemase from -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules. 14. PMID 38540719 DOI: 10.3390/biom14030299 |
0.316 |
|
| 2023 |
Gregory KS, Hall PR, Onuh JP, Mojanaga OO, Liu SM, Acharya KR. Crystal Structure of the Catalytic Domain of a Botulinum Neurotoxin Homologue from : Potential Insights into Substrate Recognition. International Journal of Molecular Sciences. 24. PMID 37628902 DOI: 10.3390/ijms241612721 |
0.304 |
|
| 2022 |
Cozier GE, Newby EC, Schwager SLU, Isaac RE, Sturrock ED, Acharya KR. Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat. The Febs Journal. PMID 35653492 DOI: 10.1111/febs.16543 |
0.316 |
|
| 2020 |
Cozier GE, Lubbe L, Sturrock ED, Acharya KR. Angiotensin-converting enzyme open for business: structural insights into the sub-domain dynamics. The Febs Journal. PMID 33067882 DOI: 10.1111/febs.15601 |
0.343 |
|
| 2020 |
Davies JR, Britton A, Liu SM, Acharya KR. High resolution crystal structures of the botulinum neurotoxin binding domains from subtypes A5 and A6. Febs Open Bio. PMID 32654405 DOI: 10.1002/2211-5463.12931 |
0.341 |
|
| 2020 |
Sharma U, Cozier GE, Sturrock ED, Acharya KR. Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin - Implications for Dual Inhibitor Design with Angiotensin Converting Enzyme. Journal of Medicinal Chemistry. PMID 32337993 DOI: 10.1021/Acs.Jmedchem.0C00441 |
0.38 |
|
| 2020 |
Cozier GE, Lubbe L, Sturrock ED, Acharya KR. ACE-domain selectivity extends beyond direct interacting residues at the active site. The Biochemical Journal. 477: 1241-1259. PMID 32195541 DOI: 10.1042/BCJ20200060 |
0.304 |
|
| 2020 |
Grozdanovic MM, Doyle CB, Liu L, Maybruck B, Kwatia MA, Thiyagarajan N, Acharya KR, Ackerman SJ. Charcot-Leyden Crystal Protein/Galectin-10 Interacts with Cationic Ribonucleases and is Required for Eosinophil Granulogenesis. The Journal of Allergy and Clinical Immunology. PMID 31982451 DOI: 10.1016/J.Jaci.2020.01.013 |
0.333 |
|
| 2020 |
Gregory KS, Liu SM, Acharya KR. Crystal structure of botulinum neurotoxin subtype A3 cell binding domain in complex with GD1a co-receptor ganglioside. Febs Open Bio. PMID 31945264 DOI: 10.1002/2211-5463.12790 |
0.392 |
|
| 2019 |
Moss S, Subramanian V, Acharya KR. Crystal structure of peptide-bound neprilysin reveals key binding interactions. Febs Letters. PMID 31514225 DOI: 10.1002/1873-3468.13602 |
0.419 |
|
| 2019 |
Sturrock ED, Lubbe L, Cozier GE, Schwager SLU, Arowolo AT, Arendse LB, Belcher ER, Acharya KR. . The Biochemical Journal. PMID 31072910 DOI: 10.1042/Bcj20190290 |
0.394 |
|
| 2018 |
Cozier GE, Arendse LB, Schwager SL, Sturrock ED, Acharya KR. Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design. Journal of Medicinal Chemistry. PMID 30372620 DOI: 10.1021/acs.jmedchem.8b01309 |
0.322 |
|
| 2018 |
Iyer S, Subramanian V, Acharya KR. C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor. Peerj. 6: e5815. PMID 30356970 DOI: 10.7717/Peerj.5815 |
0.311 |
|
| 2018 |
Moss S, Subramanian V, Acharya KR. High resolution crystal structure of substrate-free human neprilysin. Journal of Structural Biology. PMID 29906506 DOI: 10.1016/J.Jsb.2018.06.004 |
0.435 |
|
| 2018 |
Davies JR, Hackett GS, Liu SM, Acharya KR. High resolution crystal structures of the receptor-binding domain ofneurotoxin serotypes A and FA. Peerj. 6: e4552. PMID 29576992 DOI: 10.7717/Peerj.4552 |
0.373 |
|
| 2018 |
Cozier GE, Schwager SL, Sharma RK, Chibale K, Sturrock ED, Acharya KR. Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE: a molecular basis for domain-selectivity. The Febs Journal. PMID 29476645 DOI: 10.1111/Febs.14421 |
0.463 |
|
| 2018 |
Abrie JA, Moolman WJA, Cozier GE, Schwager SL, Acharya KR, Sturrock ED. Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme. Molecular Pharmacology. PMID 29371233 DOI: 10.1124/Mol.117.110866 |
0.35 |
|
| 2018 |
Iyer S, Acharya KR, Subramanian V. Prediction of structural consequences for disease causing variants in C21orf2 protein using computational approaches. Journal of Biomolecular Structure & Dynamics. 1-32. PMID 29343210 DOI: 10.1080/07391102.2018.1429313 |
0.303 |
|
| 2017 |
Davies JR, Rees J, Liu SM, Acharya KR. High resolution crystal structures of Clostridium botulinum neurotoxin A3 and A4 binding domains. Journal of Structural Biology. PMID 29288126 DOI: 10.1016/J.Jsb.2017.12.010 |
0.33 |
|
| 2017 |
Bradshaw WJ, Kirby JM, Roberts AK, Shone CC, Acharya KR. The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile. The Febs Journal. PMID 29083543 DOI: 10.1111/Febs.14310 |
0.36 |
|
| 2017 |
Bradshaw WJ, Kirby JM, Roberts AK, Shone CC, Acharya KR. Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro. The Febs Journal. PMID 28677344 DOI: 10.1111/Febs.14157 |
0.357 |
|
| 2017 |
Abu Hasan Z', Williams H, Ismail NM, Othman H, Cozier GE, Acharya KR, Isaac RE. The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae. Scientific Reports. 7: 45409. PMID 28345667 DOI: 10.1038/Srep45409 |
0.327 |
|
| 2016 |
Davies AH, McGlashan J, Posner MG, Roberts AK, Shone CC, Acharya KR. Functional significance of active site residues in the enzymatic component of the Clostridium difficile binary toxin. Biochemistry and Biophysics Reports. 8: 55-61. PMID 28955942 DOI: 10.1016/J.Bbrep.2016.08.011 |
0.35 |
|
| 2016 |
Masuyer G, Cozier GE, Kramer GJ, Bachmann BO, Acharya KR. Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor. The Febs Journal. PMID 27754586 DOI: 10.1111/Febs.13928 |
0.344 |
|
| 2016 |
Larmuth KM, Masuyer G, Douglas RG, Schwager SL, Acharya KR, Sturrock ED. Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme. The Febs Journal. 283: 1060-76. PMID 26748546 DOI: 10.1111/Febs.13647 |
0.377 |
|
| 2016 |
Liang S, Acharya KR. Structural basis of substrate specificity in porcine RNase 4. The Febs Journal. PMID 26748441 DOI: 10.1111/Febs.13646 |
0.435 |
|
| 2015 |
Harrison C, Acharya KR. A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE. Febs Open Bio. 5: 661-7. PMID 26380810 DOI: 10.1016/J.Fob.2015.08.004 |
0.4 |
|
| 2015 |
Iyer S, La-Borde PJ, Payne KA, Parsons MR, Turner AJ, Isaac RE, Acharya KR. Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site. Febs Open Bio. 5: 292-302. PMID 25905034 DOI: 10.1016/J.Fob.2015.03.013 |
0.403 |
|
| 2015 |
Bradshaw WJ, Davies AH, Chambers CJ, Roberts AK, Shone CC, Acharya KR. Molecular features of the sortase enzyme family. The Febs Journal. 282: 2097-114. PMID 25845800 DOI: 10.1111/Febs.13288 |
0.322 |
|
| 2015 |
Chambers CJ, Roberts AK, Shone CC, Acharya KR. Structure and function of a Clostridium difficile sortase enzyme. Scientific Reports. 5: 9449. PMID 25801974 DOI: 10.1038/Srep09449 |
0.388 |
|
| 2015 |
Ramaswamy S, Sleiman MH, Masuyer G, Arbez-Gindre C, Micha-Screttas M, Calogeropoulou T, Steele BR, Acharya KR. Structural basis of multivalent galactose-based dendrimer recognition by human galectin-7. The Febs Journal. 282: 372-87. PMID 25367374 DOI: 10.1111/Febs.13140 |
0.39 |
|
| 2014 |
Masuyer G, Yates CJ, Sturrock ED, Acharya KR. Angiotensin-I converting enzyme (ACE): structure, biological roles, and molecular basis for chloride ion dependence. Biological Chemistry. 395: 1135-49. PMID 25205727 DOI: 10.1515/Hsz-2014-0157 |
0.391 |
|
| 2014 |
Harrison C, Acharya KR. ACE for all - a molecular perspective. Journal of Cell Communication and Signaling. 8: 195-210. PMID 25027949 DOI: 10.1007/S12079-014-0236-8 |
0.368 |
|
| 2014 |
Kramer GJ, Mohd A, Schwager SL, Masuyer G, Acharya KR, Sturrock ED, Bachmann BO. Interkingdom pharmacology of Angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes. Acs Medicinal Chemistry Letters. 5: 346-51. PMID 24900839 DOI: 10.1021/Ml4004588 |
0.372 |
|
| 2014 |
Pham TT, Stinson B, Thiyagarajan N, Lizotte-Waniewski M, Brew K, Acharya KR. Structures of complexes of a metal-independent glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-acetylgalactosamine (UDP-GalNAc) and its hydrolysis products. The Journal of Biological Chemistry. 289: 8041-50. PMID 24459149 DOI: 10.1074/Jbc.M113.545384 |
0.578 |
|
| 2014 |
Yates CJ, Masuyer G, Schwager SL, Akif M, Sturrock ED, Acharya KR. Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE). The Journal of Biological Chemistry. 289: 1798-814. PMID 24297181 DOI: 10.1074/Jbc.M113.512335 |
0.435 |
|
| 2014 |
Masuyer G, Akif M, Czarny B, Beau F, Schwager SL, Sturrock ED, Isaac RE, Dive V, Acharya KR. Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. The Febs Journal. 281: 943-56. PMID 24289879 DOI: 10.1111/Febs.12660 |
0.426 |
|
| 2014 |
Michaud A, Acharya KR, Masuyer G, Quenech'du N, Gribouval O, Morinière V, Gubler MC, Corvol P. Absence of cell surface expression of human ACE leads to perinatal death. Human Molecular Genetics. 23: 1479-91. PMID 24163131 DOI: 10.1093/Hmg/Ddt535 |
0.322 |
|
| 2014 |
Masuyer G, Chaddock JA, Foster KA, Acharya KR. Engineered botulinum neurotoxins as new therapeutics. Annual Review of Pharmacology and Toxicology. 54: 27-51. PMID 24016211 DOI: 10.1146/Annurev-Pharmtox-011613-135935 |
0.335 |
|
| 2014 |
Douglas RG, Sharma RK, Masuyer G, Lubbe L, Zamora I, Acharya KR, Chibale K, Sturrock ED. Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors. Clinical Science (London, England : 1979). 126: 305-13. PMID 24015848 DOI: 10.1042/Cs20130403 |
0.366 |
|
| 2013 |
Thiyagarajan N, Acharya KR. Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule. Febs Open Bio. 3: 65-70. PMID 23772376 DOI: 10.1016/J.Fob.2012.12.003 |
0.444 |
|
| 2013 |
Iyer S, Holloway DE, Acharya KR. Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues. The Febs Journal. 280: 302-18. PMID 23170778 DOI: 10.1111/Febs.12071 |
0.469 |
|
| 2012 |
Walker NJ, Clark EA, Ford DC, Bullifent HL, McAlister EV, Duffield ML, Acharya KR, Oyston PC. Structure and function of cytidine monophosphate kinase from Yersinia pseudotuberculosis, essential for virulence but not for survival. Open Biology. 2: 120142. PMID 23271832 DOI: 10.1098/Rsob.120142 |
0.318 |
|
| 2012 |
Thiyagarajan N, Pham TT, Stinson B, Sundriyal A, Tumbale P, Lizotte-Waniewski M, Brew K, Acharya KR. Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Scientific Reports. 2: 940. PMID 23230506 DOI: 10.1038/Srep00940 |
0.607 |
|
| 2012 |
Akif M, Masuyer G, Bingham RJ, Sturrock ED, Isaac RE, Acharya KR. Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster. The Febs Journal. 279: 4525-34. PMID 23082758 DOI: 10.1111/Febs.12038 |
0.407 |
|
| 2012 |
Masuyer G, Schwager SL, Sturrock ED, Isaac RE, Acharya KR. Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Scientific Reports. 2: 717. PMID 23056909 DOI: 10.1038/Srep00717 |
0.34 |
|
| 2012 |
Stancombe PR, Masuyer G, Birch-Machin I, Beard M, Foster KA, Chaddock JA, Acharya KR. Engineering botulinum neurotoxin domains for activation by toxin light chain. The Febs Journal. 279: 515-23. PMID 22141396 DOI: 10.1111/J.1742-4658.2011.08444.X |
0.366 |
|
| 2012 |
Masuyer G, Jabeen T, Öberg CT, Leffler H, Nilsson UJ, Acharya KR. Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor. The Febs Journal. 279: 193-202. PMID 22059385 DOI: 10.1111/J.1742-4658.2011.08414.X |
0.382 |
|
| 2011 |
Masuyer G, Stancombe P, Chaddock JA, Acharya KR. Structures of engineered Clostridium botulinum neurotoxin derivatives. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1466-72. PMID 22139146 DOI: 10.1107/S1744309111034671 |
0.384 |
|
| 2011 |
Holloway DE, Singh UP, Shogen K, Acharya KR. Crystal structure of Onconase at 1.1 Å resolution--insights into substrate binding and collective motion. The Febs Journal. 278: 4136-49. PMID 21895975 DOI: 10.1111/J.1742-4658.2011.08320.X |
0.419 |
|
| 2011 |
Akif M, Masuyer G, Schwager SL, Bhuyan BJ, Mugesh G, Isaac RE, Sturrock ED, Acharya KR. Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril. The Febs Journal. 278: 3644-50. PMID 21810173 DOI: 10.1111/J.1742-4658.2011.08276.X |
0.421 |
|
| 2011 |
Davies AH, Roberts AK, Shone CC, Acharya KR. Super toxins from a super bug: structure and function of Clostridium difficile toxins. The Biochemical Journal. 436: 517-26. PMID 21615333 DOI: 10.1042/Bj20110106 |
0.3 |
|
| 2011 |
Holbourn KP, Malfois M, Acharya KR. First structural glimpse of CCN3 and CCN5 multifunctional signaling regulators elucidated by small angle x-ray scattering. The Journal of Biological Chemistry. 286: 22243-9. PMID 21543320 DOI: 10.1074/Jbc.M111.225755 |
0.36 |
|
| 2011 |
Clark EA, Walker N, Ford DC, Cooper IA, Oyston PC, Acharya KR. Molecular recognition of chymotrypsin by the serine protease inhibitor ecotin from Yersinia pestis. The Journal of Biological Chemistry. 286: 24015-22. PMID 21531711 DOI: 10.1074/Jbc.M111.225730 |
0.389 |
|
| 2011 |
Holbourn KP, Lloyd MD, Thompson AS, Threadgill MD, Acharya KR. Cloning, purification, crystallization and preliminary crystallographic analysis of the human histone deacetylase sirtuin 1 Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 461-463. PMID 21505241 DOI: 10.1107/S1744309111003277 |
0.309 |
|
| 2011 |
Holbourn KP, Acharya KR. Cloning, expression and purification of the CCN family of proteins in Escherichia coli. Biochemical and Biophysical Research Communications. 407: 837-41. PMID 21458411 DOI: 10.1016/J.Bbrc.2011.03.122 |
0.349 |
|
| 2011 |
Akif M, Schwager SL, Anthony CS, Czarny B, Beau F, Dive V, Sturrock ED, Acharya KR. Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide. The Biochemical Journal. 436: 53-9. PMID 21352096 DOI: 10.1042/Bj20102123 |
0.418 |
|
| 2011 |
Thiyagarajan N, Smith BD, Raines RT, Acharya KR. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A. The Febs Journal. 278: 541-9. PMID 21205197 DOI: 10.1111/J.1742-4658.2010.07976.X |
0.302 |
|
| 2011 |
Masuyer G, Beard M, Cadd VA, Chaddock JA, Acharya KR. Structure and activity of a functional derivative of Clostridium botulinum neurotoxin B. Journal of Structural Biology. 174: 52-7. PMID 21078393 DOI: 10.1016/J.Jsb.2010.11.010 |
0.35 |
|
| 2010 |
Brew K, Tumbale P, Acharya KR. Family 6 glycosyltransferases in vertebrates and bacteria: inactivation and horizontal gene transfer may enhance mutualism between vertebrates and bacteria. The Journal of Biological Chemistry. 285: 37121-7. PMID 20870714 DOI: 10.1074/Jbc.R110.176248 |
0.551 |
|
| 2010 |
Anthony CS, Corradi HR, Schwager SLU, Redelinghuys P, Georgiadis D, Dive V, Acharya KR, Sturrock ED. The N domain of human angiotensin-I-converting enzyme: The role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407 Journal of Biological Chemistry. 285: 35685-35693. PMID 20826823 DOI: 10.1074/Jbc.M110.167866 |
0.416 |
|
| 2010 |
Akif M, Ntai I, Sturrock ED, Isaac RE, Bachmann BO, Acharya KR. Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster. Biochemical and Biophysical Research Communications. 398: 532-6. PMID 20599761 DOI: 10.1016/J.Bbrc.2010.06.113 |
0.414 |
|
| 2010 |
Iyer S, Darley PI, Acharya KR. Structural insights into the binding of vascular endothelial growth factor-B by VEGFR-1(D2): recognition and specificity. The Journal of Biological Chemistry. 285: 23779-89. PMID 20501651 DOI: 10.1074/Jbc.M110.130658 |
0.319 |
|
| 2010 |
Akif M, Georgiadis D, Mahajan A, Dive V, Sturrock ED, Isaac RE, Acharya KR. High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs. Journal of Molecular Biology. 400: 502-17. PMID 20488190 DOI: 10.1016/J.Jmb.2010.05.024 |
0.445 |
|
| 2010 |
de Andrade MC, Affonso R, Fernandes FB, Febba AC, da Silva ID, Stella RC, Marson O, Jubilut GN, Hirata IY, Carmona AK, Corradi H, Acharya KR, Sturrock ED, Casarini DE. Spectroscopic and structural analysis of somatic and N-domain angiotensin I-converting enzyme isoforms from mesangial cells from Wistar and spontaneously hypertensive rats. International Journal of Biological Macromolecules. 47: 238-43. PMID 20435057 DOI: 10.1016/J.Ijbiomac.2010.04.015 |
0.391 |
|
| 2010 |
Sundriyal A, Roberts AK, Ling R, McGlashan J, Shone CC, Acharya KR. Expression, purification and cell cytotoxicity of actin-modifying binary toxin from Clostridium difficile. Protein Expression and Purification. 74: 42-8. PMID 20433927 DOI: 10.1016/J.Pep.2010.04.014 |
0.319 |
|
| 2010 |
Cozier GE, Leese MP, Lloyd MD, Baker MD, Thiyagarajan N, Acharya KR, Potter BV. Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors. Biochemistry. 49: 3464-76. PMID 20297840 DOI: 10.1021/Bi902178W |
0.339 |
|
| 2010 |
Woo LWL, Jackson T, Putey A, Cozier G, Leonard P, Acharya KR, Chander SK, Purohit A, Reed MJ, Potter BVl. Abstract 727: Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a diaryl template Cancer Research. 70: 727-727. DOI: 10.1158/1538-7445.Am10-727 |
0.307 |
|
| 2009 |
Sundriyal A, Roberts AK, Shone CC, Acharya KR. Structural basis for substrate recognition in the enzymatic component of ADP-ribosyltransferase toxin CDTa from Clostridium difficile. The Journal of Biological Chemistry. 284: 28713-9. PMID 19692332 DOI: 10.1074/jbc.M109.043018 |
0.332 |
|
| 2009 |
Jamaluddin H, Tumbale P, Ferns TA, Thiyagarajan N, Brew K, Acharya KR. Crystal structure of alpha-1,3-galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNPbetaGal). Biochemical and Biophysical Research Communications. 385: 601-4. PMID 19486884 DOI: 10.1016/J.Bbrc.2009.05.111 |
0.593 |
|
| 2009 |
Holbourn KP, Perbal B, Acharya KR. Proteins on the catwalk: modelling the structural domains of the CCN family of proteins. Journal of Cell Communication and Signaling. 3: 25-41. PMID 19424823 DOI: 10.1007/S12079-009-0048-4 |
0.36 |
|
| 2009 |
Masuyer G, Thiyagarajan N, James PL, Marks PM, Chaddock JA, Acharya KR. Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A. Biochemical and Biophysical Research Communications. 381: 50-3. PMID 19351593 DOI: 10.1016/J.Bbrc.2009.02.003 |
0.405 |
|
| 2009 |
Holloway DE, Chavali GB, Leonidas DD, Baker MD, Acharya KR. Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study. Biopolymers. 91: 995-1008. PMID 19191310 DOI: 10.1002/Bip.21158 |
0.412 |
|
| 2008 |
Leonard P, Scotney PD, Jabeen T, Iyer S, Fabri LJ, Nash AD, Acharya KR. Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment. Journal of Molecular Biology. 384: 1203-17. PMID 18930733 DOI: 10.1016/J.Jmb.2008.09.076 |
0.301 |
|
| 2008 |
Holbourn KP, Acharya KR, Perbal B. The CCN family of proteins: structure-function relationships. Trends in Biochemical Sciences. 33: 461-73. PMID 18789696 DOI: 10.1016/J.Tibs.2008.07.006 |
0.346 |
|
| 2008 |
Tumbale P, Jamaluddin H, Thiyagarajan N, Acharya KR, Brew K. Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase. Glycobiology. 18: 1036-43. PMID 18782853 DOI: 10.1093/Glycob/Cwn083 |
0.625 |
|
| 2008 |
Ulrich M, Petre A, Youhnovski N, Prömm F, Schirle M, Schumm M, Pero RS, Doyle A, Checkel J, Kita H, Thiyagarajan N, Acharya KR, Schmid-Grendelmeier P, Simon HU, Schwarz H, et al. Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. The Journal of Biological Chemistry. 283: 28629-40. PMID 18694936 DOI: 10.1074/Jbc.M801196200 |
0.38 |
|
| 2008 |
Tumbale P, Jamaluddin H, Thiyagarajan N, Brew K, Acharya KR. Structural basis of UDP-galactose binding by alpha-1,3-galactosyltransferase (alpha3GT): role of negative charge on aspartic acid 316 in structure and activity. Biochemistry. 47: 8711-8. PMID 18651752 DOI: 10.1021/Bi800852A |
0.647 |
|
| 2008 |
Jabeen T, Leonard P, Jamaluddin H, Acharya KR. Structure of mouse IP-10, a chemokine. Acta Crystallographica. Section D, Biological Crystallography. 64: 611-9. PMID 18560148 DOI: 10.1107/S0907444908007026 |
0.406 |
|
| 2008 |
Kazakou K, Holloway DE, Prior SH, Subramanian V, Acharya KR. Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications. Journal of Molecular Biology. 380: 206-22. PMID 18508078 DOI: 10.1016/J.Jmb.2008.04.070 |
0.361 |
|
| 2008 |
Jamaluddin H, Tumbale P, Withers SG, Acharya KR, Brew K. Corrigendum to "Conformational Changes Induced by Binding of UDP-2F-galactose to α-1,3 Galactosyltransferase-Implications for Catalysis" [J. Mol. Biol. 369 (2007) 1270-1281] (DOI:10.1016/j.jmb.2007.04.012) Journal of Molecular Biology. 378: 295-296. DOI: 10.1016/J.Jmb.2008.02.030 |
0.614 |
|
| 2007 |
Crabtree B, Thiyagarajan N, Prior SH, Wilson P, Iyer S, Ferns T, Shapiro R, Brew K, Subramanian V, Acharya KR. Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry. 46: 11810-8. PMID 17900154 DOI: 10.1021/Bi701333H |
0.557 |
|
| 2007 |
Hamze AB, Wei S, Bahudhanapati H, Kota S, Acharya KR, Brew K. Constraining specificity in the N-domain of tissue inhibitor of metalloproteinases-1; gelatinase-selective inhibitors. Protein Science : a Publication of the Protein Society. 16: 1905-13. PMID 17660250 DOI: 10.1110/Ps.072978507 |
0.536 |
|
| 2007 |
Rivière G, Michaud A, Corradi HR, Sturrock ED, Acharya KR, Cogez V, Bohin J, Vieau D, Corvol P. Characterization of the first angiotensin-converting like enzyme in bacteria: Ancestor ACE is already active. Gene. 399: 81-90. PMID 17597310 DOI: 10.1016/J.Gene.2007.05.010 |
0.378 |
|
| 2007 |
Singh UP, Ardelt W, Saxena SK, Holloway DE, Vidunas E, Lee HS, Saxena A, Shogen K, Acharya KR. Enzymatic and structural characterisation of amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes. Journal of Molecular Biology. 371: 93-111. PMID 17560606 DOI: 10.1016/J.Jmb.2007.04.071 |
0.404 |
|
| 2007 |
Jamaluddin H, Tumbale P, Withers SG, Acharya KR, Brew K. Conformational Changes Induced by Binding UDP-2F-galactose to α-1,3 Galactosyltransferase- Implications for Catalysis Journal of Molecular Biology. 369: 1270-1281. PMID 17493636 DOI: 10.1016/J.Jmb.2007.04.012 |
0.644 |
|
| 2007 |
Corradi HR, Chitapi I, Sewell BT, Georgiadis D, Dive V, Sturrock ED, Acharya KR. The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380. Biochemistry. 46: 5473-8. PMID 17439247 DOI: 10.1021/Bi700275E |
0.422 |
|
| 2007 |
Crabtree B, Holloway DE, Baker MD, Acharya KR, Subramanian V. Biological and structural features of murine angiogenin-4, an angiogenic protein. Biochemistry. 46: 2431-43. PMID 17279775 DOI: 10.1021/Bi062158N |
0.401 |
|
| 2007 |
Rummel A, Eichner T, Weil T, Karnath T, Gutcaits A, Mahrhold S, Sandhoff K, Proia RL, Acharya KR, Bigalke H, Binz T. Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept. Proceedings of the National Academy of Sciences of the United States of America. 104: 359-64. PMID 17185412 DOI: 10.1073/Pnas.0609713104 |
0.38 |
|
| 2007 |
Iyer S, Wei S, Brew K, Acharya KR. Crystal structure of the catalytic domain of matrix metalloproteinase-1 in complex with the inhibitory domain of tissue inhibitor of metalloproteinase-1. The Journal of Biological Chemistry. 282: 364-71. PMID 17050530 DOI: 10.1074/Jbc.M607625200 |
0.536 |
|
| 2006 |
Corradi HR, Corrigall AV, Boix E, Mohan CG, Sturrock ED, Meissner PN, Acharya KR. Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen. The Journal of Biological Chemistry. 281: 38625-33. PMID 17046834 DOI: 10.1074/Jbc.M606640200 |
0.441 |
|
| 2006 |
Watermeyer JM, Sewell BT, Schwager SL, Natesh R, Corradi HR, Acharya KR, Sturrock ED. Structure of testis ACE glycosylation mutants and evidence for conserved domain movement. Biochemistry. 45: 12654-63. PMID 17042482 DOI: 10.1021/Bi061146Z |
0.333 |
|
| 2006 |
Corradi HR, Schwager SL, Nchinda AT, Sturrock ED, Acharya KR. Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design. Journal of Molecular Biology. 357: 964-74. PMID 16476442 DOI: 10.1016/J.Jmb.2006.01.048 |
0.385 |
|
| 2006 |
Baker MD, Holloway DE, Swaminathan GJ, Acharya KR. Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Biochemistry. 45: 416-26. PMID 16401072 DOI: 10.1021/Bi0518592 |
0.415 |
|
| 2006 |
Baker MD, Holloway DE, Swaminathan GJ, Acharya KR. Erratum: Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5′-ATP, Ap3A, Ap4A, and Ap5A (Biochemistry (January 17, 2006) 45, 2 (416-426)) Biochemistry. 45. DOI: 10.1021/Bi068008U |
0.347 |
|
| 2005 |
Sundara Baalaji N, Acharya KR, Singh TP, Krishnaswamy S. High-resolution diffraction from crystals of a membrane-protein complex: bacterial outer membrane protein OmpC complexed with the antibacterial eukaryotic protein lactoferrin. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 773-5. PMID 16511154 DOI: 10.1107/S1744309105022086 |
0.351 |
|
| 2005 |
Holloway DE, Chavali GB, Hares MC, Subramanian V, Acharya KR. Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies. Acta Crystallographica. Section D, Biological Crystallography. 61: 1568-78. PMID 16301790 DOI: 10.1107/S0907444905029616 |
0.35 |
|
| 2005 |
Swaminathan GJ, Myszka DG, Katsamba PS, Ohnuki LE, Gleich GJ, Acharya KR. Eosinophil-granule major basic protein, a C-type lectin, binds heparin. Biochemistry. 44: 14152-8. PMID 16245931 DOI: 10.1021/Bi051112B |
0.372 |
|
| 2005 |
Balyasnikova IV, Woodman ZL, Albrecht RF, Natesh R, Acharya KR, Sturrock ED, Danilov SM. Localization of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies. Journal of Proteome Research. 4: 258-67. PMID 15822901 DOI: 10.1021/Pr049859W |
0.321 |
|
| 2005 |
Holbourn KP, Sutton JM, Evans HR, Shone CC, Acharya KR. Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase. Proceedings of the National Academy of Sciences of the United States of America. 102: 5357-62. PMID 15809419 DOI: 10.1073/pnas.0501525102 |
0.32 |
|
| 2005 |
Acharya KR, Lloyd MD. The advantages and limitations of protein crystal structures. Trends in Pharmacological Sciences. 26: 10-4. PMID 15629199 DOI: 10.1016/J.Tips.2004.10.011 |
0.352 |
|
| 2005 |
Lloyd MD, Pederick RL, Natesh R, Woo LW, Purohit A, Reed MJ, Acharya KR, Potter BV. Crystal structure of human carbonic anhydrase II at 1.95 A resolution in complex with 667-coumate, a novel anti-cancer agent. The Biochemical Journal. 385: 715-20. PMID 15453828 DOI: 10.1042/Bj20041037 |
0.355 |
|
| 2004 |
Sturrock ED, Natesh R, van Rooyen JM, Acharya KR. Structure of angiotensin I-converting enzyme. Cellular and Molecular Life Sciences : Cmls. 61: 2677-86. PMID 15549168 DOI: 10.1007/S00018-004-4239-0 |
0.348 |
|
| 2004 |
Baker MD, Gendlina I, Collins CM, Acharya KR. Crystal structure of a dimeric form of streptococcal pyrogenic exotoxin A (SpeA1). Protein Science : a Publication of the Protein Society. 13: 2285-90. PMID 15295110 DOI: 10.1110/Ps.04826804 |
0.368 |
|
| 2004 |
Errico M, Riccioni T, Iyer S, Pisano C, Acharya KR, Persico MG, De Falco S. Identification of placenta growth factor determinants for binding and activation of Flt-1 receptor. The Journal of Biological Chemistry. 279: 43929-39. PMID 15272021 DOI: 10.1074/Jbc.M401418200 |
0.391 |
|
| 2004 |
Natesh R, Schwager SLU, Evans HR, Sturrock ED, Acharya KR. Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme Biochemistry. 43: 8718-8724. PMID 15236580 DOI: 10.1021/Bi049480N |
0.447 |
|
| 2004 |
Zhang Y, Deshpande A, Xie Z, Natesh R, Acharya KR, Brew K. Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology. 14: 1295-302. PMID 15229192 DOI: 10.1093/Glycob/Cwh119 |
0.64 |
|
| 2004 |
Turton K, Natesh R, Thiyagarajan N, Chaddock JA, Acharya KR. Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose Glycobiology. 14: 923-929. PMID 15201215 DOI: 10.1093/Glycob/Cwh114 |
0.329 |
|
| 2004 |
Baker MD, Acharya KR. Superantigens: Structure-function relationships International Journal of Medical Microbiology. 293: 529-537. PMID 15149028 DOI: 10.1078/1438-4221-00298 |
0.337 |
|
| 2004 |
Holloway DE, Chavali GB, Hares MC, Baker MD, Subbarao GV, Shapiro R, Acharya KR. Crystallographic Studies on Structural Features That Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80, and Residues 38-41 Biochemistry. 43: 1230-1241. PMID 14756559 DOI: 10.1021/bi035654+ |
0.341 |
|
| 2004 |
Leonidas DD, Chavali GB, Oikonomakos NG, Chrysina ED, Kosmopoulou MN, Vlassi M, Frankling C, Acharya KR. High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors. Protein Science : a Publication of the Protein Society. 12: 2559-74. PMID 14573867 DOI: 10.1110/ps.03196603 |
0.311 |
|
| 2004 |
Papageorgiou AC, Baker MD, McLeod JD, Goda SK, Manzotti CN, Sansom DM, Tranter HS, Acharya KR. Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition. The Journal of Biological Chemistry. 279: 1297-303. PMID 14559915 DOI: 10.1074/Jbc.M307333200 |
0.408 |
|
| 2003 |
Acharya KR, Sturrock ED, Riordan JF, Ehlers MR. Ace revisited: a new target for structure-based drug design. Nature Reviews. Drug Discovery. 2: 891-902. PMID 14668810 DOI: 10.1038/Nrd1227 |
0.341 |
|
| 2003 |
Zhang Y, Swaminathan GJ, Deshpande A, Boix E, Natesh R, Xie Z, Acharya KR, Brew K. Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity. Biochemistry. 42: 13512-21. PMID 14621997 DOI: 10.1021/Bi035430R |
0.62 |
|
| 2003 |
Guy JL, Jackson RM, Acharya KR, Sturrock ED, Hooper NM, Turner AJ. Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence. Biochemistry. 42: 13185-92. PMID 14609329 DOI: 10.1021/Bi035268S |
0.412 |
|
| 2003 |
Evans HR, Sutton JM, Holloway DE, Ayriss J, Shone CC, Acharya KR. The Crystal Structure of C3stau2 from Staphylococcus aureus and Its Complex with NAD Journal of Biological Chemistry. 278: 45924-45930. PMID 12933793 DOI: 10.1074/Jbc.M307719200 |
0.472 |
|
| 2003 |
Chavali GB, Papageorgiou AC, Olson KA, Fett JW, Hu GF, Shapiro R, Acharya KR. The crystal structure of human angiogenin in complex with an antitumor neutralizing antibody Structure. 11: 875-885. PMID 12842050 DOI: 10.1016/S0969-2126(03)00131-X |
0.371 |
|
| 2003 |
Swaminathan GJ, Holloway DE, Colvin RA, Campanella GK, Papageorgiou AC, Luster AD, Acharya KR. Crystal structures of oligomeric forms of the IP-10/CXCL10 chemokine. Structure (London, England : 1993). 11: 521-32. PMID 12737818 DOI: 10.1016/S0969-2126(03)00070-4 |
0.379 |
|
| 2003 |
Teufel DP, Kao RY, Acharya KR, Shapiro R. Mutational analysis of the complex of human RNase inhibitor and human eosinophil-derived neurotoxin (RNase 2). Biochemistry. 42: 1451-9. PMID 12578357 DOI: 10.1021/Bi026852O |
0.328 |
|
| 2003 |
Gordon K, Redelinghuys P, Schwager SL, Ehlers MR, Papageorgiou AC, Natesh R, Acharya KR, Sturrock ED. Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme. The Biochemical Journal. 371: 437-42. PMID 12542396 DOI: 10.1042/Bj20021842 |
0.394 |
|
| 2003 |
Baker MD, Acharya KR. Superantigens. Structure, function, and diversity. Methods of Molecular Biology. 214: 1-31. DOI: 10.1128/9781555815844.Ch8 |
0.348 |
|
| 2002 |
Turton K, Chaddock JA, Acharya KR. Botulinum and tetanus neurotoxins: structure, function and therapeutic utility Trends in Biochemical Sciences. 27: 552-558. PMID 12417130 DOI: 10.1016/S0968-0004(02)02177-1 |
0.326 |
|
| 2002 |
Mohan CG, Boix E, Evans HR, Nikolovski Z, Nogués MV, Cuchillo CM, Acharya KR. The crystal structure of eosinophil cationic protein in complex with 2′,5′-ADP at 2.0 Å resolution reveals the details of the ribonucleolytic active site Biochemistry. 41: 12100-12106. PMID 12356310 DOI: 10.1021/Bi0264521 |
0.438 |
|
| 2002 |
Holloway DE, Shapiro R, Hares MC, Leonidas DD, Acharya KR. Guest-host crosstalk in an angiogenin - RNase a chimeric protein Biochemistry. 41: 10482-10489. PMID 12173935 DOI: 10.1021/Bi026151R |
0.335 |
|
| 2002 |
Boix E, Zhang Y, Swaminathan GJ, Brew K, Acharya KR. Structural basis of ordered binding of donor and acceptor substrates to the retaining glycosyltransferase, alpha-1,3-galactosyltransferase. The Journal of Biological Chemistry. 277: 28310-8. PMID 12011052 DOI: 10.1074/Jbc.M202631200 |
0.622 |
|
| 2002 |
Iyer S, Acharya KR. Role of placenta growth factor in cardiovascular health Trends in Cardiovascular Medicine. 12: 128-134. PMID 12007738 DOI: 10.1016/S1050-1738(01)00164-5 |
0.304 |
|
| 2002 |
Swaminathan GJ, Holloway DE, Veluraja K, Acharya KR. Atomic resolution (0.98 A) structure of eosinophil-derived neurotoxin. Biochemistry. 41: 3341-52. PMID 11876642 DOI: 10.1021/bi015911f |
0.326 |
|
| 2002 |
Leonidas DD, Shapiro R, Subbarao GV, Russo A, Acharya KR. Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency Biochemistry. 41: 2552-2562. PMID 11851402 DOI: 10.1021/bi015768q |
0.336 |
|
| 2002 |
Ackerman SJ, Liu L, Kwatia MA, Savage MP, Leonidas DD, Swaminathan GJ, Acharya KR. Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion. The Journal of Biological Chemistry. 277: 14859-68. PMID 11834744 DOI: 10.1074/Jbc.M200221200 |
0.414 |
|
| 2002 |
Baker MD, Papageorgiou AC, Titball RW, Miller J, White S, Lingard B, Lee JJ, Cavanagh D, Kehoe MA, Robinson JH, Acharya KR. Structural and functional role of threonine 112 in a superantigen Staphylococcus aureus enterotoxin B. The Journal of Biological Chemistry. 277: 2756-62. PMID 11704673 DOI: 10.1074/Jbc.M109369200 |
0.42 |
|
| 2001 |
Greene LH, Chrysina ED, Irons LI, Papageorgiou AC, Acharya KR, Brew K. Role of conserved residues in structure and stability: Tryptophans of human serum retinol-binding protein, a model for the lipocalin superfamily Protein Science. 10: 2301-2316. PMID 11604536 DOI: 10.1110/Ps.22901 |
0.588 |
|
| 2001 |
Boix E, Swaminathan GJ, Zhang Y, Natesh R, Brew K, Acharya KR. Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus. The Journal of Biological Chemistry. 276: 48608-14. PMID 11592969 DOI: 10.1074/Jbc.M108828200 |
0.604 |
|
| 2001 |
Leonidas DD, Chavali GB, Jardine AM, Li S, Shapiro R, Acharya KR. Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography Protein Science. 10: 1669-1676. PMID 11468363 DOI: 10.1110/ps.13601 |
0.327 |
|
| 2001 |
Holloway DE, Hares MC, Shapiro R, Subramanian V, Acharya KR. High-level expression of three members of the murine angiogenin family in Escherichia coli and purification of the recombinant proteins Protein Expression and Purification. 22: 307-317. PMID 11437607 DOI: 10.1006/Prep.2001.1434 |
0.329 |
|
| 2001 |
Poulas K, Eliopoulos E, Vatzaki E, Navaza J, Kontou M, Oikonomakos N, Acharya KR, Tzartos SJ. Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies. Febs Journal. 268: 3685-3693. PMID 11432734 DOI: 10.1046/J.1432-1327.2001.02274.X |
0.357 |
|
| 2001 |
Baker M, Gutman DM, Papageorgiou AC, Collins CM, Acharya KR. Structural features of a zinc binding site in the superantigen strepococcal pyrogenic exotoxin A (SpeA1): implications for MHC class II recognition. Protein Science : a Publication of the Protein Society. 10: 1268-73. PMID 11369867 DOI: 10.1110/Ps.330101 |
0.414 |
|
| 2001 |
Leonidas DD, Boix E, Prill R, Suzuki M, Turton R, Minson K, Swaminathan GJ, Youle RJ, Acharya KR. Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. The Journal of Biological Chemistry. 276: 15009-17. PMID 11154698 DOI: 10.1074/Jbc.M010585200 |
0.335 |
|
| 2000 |
Papageorgiou AC, Acharya KR. Microbial superantigens: From structure to function Trends in Microbiology. 8: 369-375. PMID 10920396 DOI: 10.1016/S0966-842X(00)01793-5 |
0.311 |
|
| 2000 |
Chrysina ED, Brew K, Acharya KR. Crystal structures of Apo- and holo-bovine α-lactalbumin at 2.2-Å resolution reveal an effect of calcium on inter-lobe interactions Journal of Biological Chemistry. 275: 37021-37029. PMID 10896943 DOI: 10.1074/jbc.M004752200 |
0.569 |
|
| 2000 |
Papageorgiou AC, Plano LRW, Collins CM, Acharya KR. Structural similarities and differences in Staphylococcus aureus exfoliative toxins A and B as revealed by their crystal structures Protein Science. 9: 610-618. PMID 10752623 DOI: 10.1110/Ps.9.3.610 |
0.314 |
|
| 1999 |
Kontou M, Leonidas DD, Vatzaki EH, Tsantili P, Mamalaki A, Oikonomakos NG, Acharya KR, Tzartos SJ. The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor. Febs Journal. 267: 2389-2397. PMID 10759865 DOI: 10.1046/J.1432-1327.2000.01252.X |
0.366 |
|
| 1999 |
Boix E, Leonidas DD, Nikolovski Z, Nogués MV, Cuchillo CM, Acharya KR. Crystal structure of eosinophil cationic protein at 2.4 A resolution Biochemistry. 38: 16794-16801. PMID 10606511 DOI: 10.1021/Bi9919145 |
0.453 |
|
| 1999 |
Swaminathan GJ, Leonidas DD, Savage MP, Ackerman SJ, Acharya KR. Selective recognition of mannose by the human eosinophil Charcot-Leyden crystal protein (galectin-10): a crystallographic study at 1.8 A resolution. Biochemistry. 38: 13837-43. PMID 10529229 DOI: 10.1021/Bi990756E |
0.416 |
|
| 1999 |
Greene LH, Grobler JA, Malinovskii VA, Tian J, Acharya KR, Brew K. Stability, activity and flexibility in α-lactalbumin Protein Engineering. 12: 581-587. PMID 10436084 |
0.538 |
|
| 1999 |
Vatzaki EH, Allen SC, Leonidas DD, Trautwein-Fritz K, Stackhouse J, Benner SA, Acharya KR. Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution. European Journal of Biochemistry / Febs. 260: 176-82. PMID 10091597 DOI: 10.1046/J.1432-1327.1999.00142.X |
0.386 |
|
| 1999 |
Leonidas DD, Shapiro R, Allen SC, Subbarao GV, Veluraja K, Acharya KR. Refined crystal structures of native human angiogenin and two active site variants: Implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth Journal of Molecular Biology. 285: 1209-1233. PMID 9918722 DOI: 10.1006/jmbi.1998.2378 |
0.352 |
|
| 1999 |
Papageorgiou AC, Collins CM, Gutman DM, Kline JB, O'Brien SM, Tranter HS, Acharya KR. Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors. The Embo Journal. 18: 9-21. PMID 9878045 DOI: 10.1093/Emboj/18.1.9 |
0.371 |
|
| 1998 |
Leonidas DD, Vatzaki EH, Vorum H, Celis JE, Madsen P, Acharya KR. Structural basis for the recognition of carbohydrates by human galectin- 7 Biochemistry. 37: 13930-13940. PMID 9760227 DOI: 10.1021/bi981056x |
0.334 |
|
| 1998 |
Chandra N, Brew K, Acharya KR. Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin. Biochemistry. 37: 4767-72. PMID 9537992 DOI: 10.1021/Bi973000T |
0.585 |
|
| 1997 |
Papageorgiou AC, Shapiro R, Acharya KR. Molecular recognition of human angiogenin by placental ribonuclease inhibitor - An X-ray crystallographic study at 2.0 Å resolution Embo Journal. 16: 5162-5177. PMID 9311977 DOI: 10.1093/Emboj/16.17.5162 |
0.338 |
|
| 1997 |
Papageorgiou AC, Acharya KR. Superantigens as immunomodulators: Recent structural insights Structure. 5: 991-996. PMID 9309216 DOI: 10.1016/S0969-2126(97)00252-9 |
0.314 |
|
| 1997 |
Schad EM, Papageorgiou AC, Svensson LA, Acharya KR. A structural and functional comparison of staphylococcal enterotoxins A and C2 reveals remarkable similarity and dissimilarity Journal of Molecular Biology. 269: 270-280. PMID 9191070 DOI: 10.1006/Jmbi.1997.1023 |
0.361 |
|
| 1997 |
Leonidas DD, Shapiro R, Irons LI, Russo N, Acharya KR. Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution. Biochemistry. 36: 5578-88. PMID 9154942 DOI: 10.1021/bi9700330 |
0.36 |
|
| 1996 |
Papageorgiou AC, Quinn CP, Beer D, Brehm RD, Tranter HS, Bonventre PF, Acharya KR. Crystal structure of a biologically inactive mutant of toxic shock syndrome toxin-1 at 2.5 Å resolution Protein Science. 5: 1737-1741. PMID 8844860 DOI: 10.1002/Pro.5560050826 |
0.407 |
|
| 1996 |
Pike ACW, Brew K, Acharya KR. Crystal structures of guinea-pig, goat and bovine α-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase Structure. 4: 691-703. PMID 8805552 DOI: 10.1016/S0969-2126(96)00075-5 |
0.644 |
|
| 1995 |
Leonidas DD, Elbert BL, Zhou Z, Leffler H, Ackerman SJ, Acharya KR. Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure (London, England : 1993). 3: 1379-93. PMID 8747464 DOI: 10.1016/S0969-2126(01)00275-1 |
0.345 |
|
| 1995 |
Papageorgiou AC, Acharya KR, Shapiro R, Passalacqua EF, Brehm RD, Tranter HS. Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site Structure. 3: 769-779. PMID 7582894 DOI: 10.1016/S0969-2126(01)00212-X |
0.419 |
|
| 1994 |
Acharya KR, Shapiro R, Allen SC, Riordan JF, Vallee BL. Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease Proceedings of the National Academy of Sciences of the United States of America. 91: 2915-2919. PMID 8159679 DOI: 10.1073/Pnas.91.8.2915 |
0.336 |
|
| 1994 |
Pike ACW, Acharya KR. A structural basis for the interaction of urea with lysozyme Protein Science. 3: 706-710. PMID 8003989 DOI: 10.1002/Pro.5560030419 |
0.456 |
|
| 1994 |
Acharya KR, Stuart DI, Phillips DC, McKenzie HA, Teahan CG. Models of the three-dimensional structures of echidna, horse, and pigeon lysozymes: calcium-binding lysozymes and their relationship with alpha-lactalbumins. Journal of Protein Chemistry. 13: 569-84. PMID 7832986 DOI: 10.1007/Bf01901539 |
0.371 |
|
| 1994 |
Allen SC, Acharya KR, Palmer KA, Shapiro R, Vallee BL, Scheraga HA. A comparison of the predicted and X-ray structures of angiogenin. Implications for further studies of model building of homologous proteins. Journal of Protein Chemistry. 13: 649-58. PMID 7702747 DOI: 10.1007/Bf01890464 |
0.378 |
|
| 1993 |
Passalacqua EF, Brehm RD, Acharya KR, Tranter HS. Crystallization and preliminary X-ray analysis of a microbial superantigen staphylococcal enterotoxin C2 Journal of Molecular Biology. 233: 170-172. PMID 8377185 DOI: 10.1006/Jmbi.1993.1493 |
0.303 |
|
| 1993 |
Robson KJ, Gamble Y, Acharya KR. Molecular modelling of malaria calmodulin suggests that it is not a suitable target for novel antimalarials Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 340: 39-53. PMID 8099744 DOI: 10.1098/Rstb.1993.0047 |
0.372 |
|
| 1992 |
Acharya KR, Subramanian V, Shapiro R, Riordan JF, Vallee BL. Crystallization and preliminary X-ray analysis of human angiogenin Journal of Molecular Biology. 228: 1269-1270. PMID 1474591 DOI: 10.1016/0022-2836(92)90333-F |
0.314 |
|
| 1992 |
Passalacqua EF, Brehm RD, Acharya KR, Tranter HS. Purification, crystallization and preliminary X-ray analysis of toxic shock syndrome toxin-1 from Staphylococcus aureus Journal of Molecular Biology. 228: 983-986. PMID 1469731 DOI: 10.1016/0022-2836(92)90882-K |
0.301 |
|
| 1991 |
Acharya KR, Ren JS, Stuart DI, Phillips DC, Fenna RE. Crystal structure of human alpha-lactalbumin at 1.7 A resolution. Journal of Molecular Biology. 221: 571-81. PMID 1920433 DOI: 10.1016/0022-2836(91)80073-4 |
0.364 |
|
| 1990 |
Johnson LN, Acharya KR, Jordan MD, McLaughlin PJ. Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex. Journal of Molecular Biology. 211: 645-61. PMID 2106586 DOI: 10.1016/0022-2836(90)90271-M |
0.313 |
|
| 1988 |
Sprang SR, Acharya KR, Goldsmith EJ, Stuart DI, Varvill K, Fletterick RJ, Madsen NB, Johnson LN. Structural changes in glycogen phosphorylase induced by phosphorylation. Nature. 336: 215-21. PMID 3194008 DOI: 10.1038/336215A0 |
0.332 |
|
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