| Year |
Citation |
Score |
| 2024 |
Carrillo AK, Kadayat TM, Hwang JY, Chen Y, Zhu F, Holbrook G, Gillingwater K, Connelly MC, Yang L, Kaiser M, Guy RK. Antitrypanosomal Chloronitrobenzamides. Journal of Medicinal Chemistry. PMID 38363074 DOI: 10.1021/acs.jmedchem.3c01680 |
0.656 |
|
| 2015 |
Kang CH, Yun JI, Lee K, Lee CO, Lee HK, Yun CS, Hwang JY, Cho SY, Jung H, Kim P, Ha JD, Jeon JH, Choi SU, Jeong HG, Kim HR, et al. Development of potent ALK inhibitor and its molecular inhibitory mechanism against NSCLC harboring EML4-ALK proteins. Biochemical and Biophysical Research Communications. PMID 26168728 DOI: 10.1016/J.Bbrc.2015.07.027 |
0.304 |
|
| 2013 |
Hwang JY, Smithson DC, Holbrook G, Zhu F, Connelly MC, Kaiser M, Brun R, Kiplin Guy R. Optimization of the electrophile of chloronitrobenzamide leads active against Trypanosoma brucei. Bioorganic & Medicinal Chemistry Letters. 23: 4127-31. PMID 23746473 DOI: 10.1016/j.bmcl.2013.05.049 |
0.714 |
|
| 2013 |
Hwang JY, Smithson D, Zhu F, Holbrook G, Connelly MC, Kaiser M, Brun R, Guy RK. Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for human African trypanosomiasis (HAT). Journal of Medicinal Chemistry. 56: 2850-60. PMID 23484493 DOI: 10.1021/jm301687p |
0.722 |
|
| 2013 |
Hwang JY, Attia RR, Carrillo AK, Connelly MC, Guy RK. Synthesis and evaluation of methylsulfonylnitrobenzamides (MSNBAs) as inhibitors of the thyroid hormone receptor-coactivator interaction. Bioorganic & Medicinal Chemistry Letters. 23: 1891-5. PMID 23414840 DOI: 10.1016/j.bmcl.2012.12.055 |
0.768 |
|
| 2012 |
Hwang JY, Attia RR, Zhu F, Yang L, Lemoff A, Jeffries C, Connelly MC, Guy RK. Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors. Journal of Medicinal Chemistry. 55: 2301-10. PMID 22324546 DOI: 10.1021/Jm201546M |
0.776 |
|
| 2011 |
Hwang JY, Kawasuji T, Lowes DJ, Clark JA, Connelly MC, Zhu F, Guiguemde WA, Sigal MS, Wilson EB, Derisi JL, Guy RK. Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity. Journal of Medicinal Chemistry. 54: 7084-93. PMID 21910466 DOI: 10.1021/jm200636z |
0.71 |
|
| 2011 |
Sadana P, Hwang JY, Attia RR, Arnold LA, Neale G, Guy RK. Similarities and differences between two modes of antagonism of the thyroid hormone receptor. Acs Chemical Biology. 6: 1096-106. PMID 21815645 DOI: 10.1021/cb200092v |
0.694 |
|
| 2011 |
Johnson RL, Hwang JY, Arnold LA, Huang R, Wichterman J, Augustinaite I, Austin CP, Inglese J, Guy RK, Huang W. A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2. Journal of Biomolecular Screening. 16: 618-27. PMID 21482722 DOI: 10.1177/1087057111402199 |
0.66 |
|
| 2011 |
Hwang JY, Huang W, Arnold LA, Huang R, Attia RR, Connelly M, Wichterman J, Zhu F, Augustinaite I, Austin CP, Inglese J, Johnson RL, Guy RK. Methylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone. The Journal of Biological Chemistry. 286: 11895-908. PMID 21321127 DOI: 10.1074/jbc.M110.200436 |
0.775 |
|
| 2010 |
Hwang JY, Smithson D, Connelly M, Maier J, Zhu F, Guy KR. Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis. Bioorganic & Medicinal Chemistry Letters. 20: 149-52. PMID 19963377 DOI: 10.1016/j.bmcl.2009.11.022 |
0.713 |
|
| 2009 |
Hwang JY, Arnold LA, Zhu F, Kosinski A, Mangano TJ, Setola V, Roth BL, Guy RK. Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors. Journal of Medicinal Chemistry. 52: 3892-901. PMID 19469546 DOI: 10.1021/Jm9002704 |
0.623 |
|
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