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Esther Woon - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 
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18/42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Perry GS, Das M, Woon ECY. Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets. Journal of Medicinal Chemistry. 64: 16974-17003. PMID 34792334 DOI: 10.1021/acs.jmedchem.1c01694  0.342
2015 Toh JDW, Sun L, Lau LZM, Tan J, Low JJA, Tang CWQ, Cheong EJY, Tan MJH, Chen Y, Hong W, Gao YG, Woon ECY. A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N(6)-methyladenosine demethylase FTO. Chemical Science. 6: 112-122. PMID 28553460 DOI: 10.1039/c4sc02554g  0.411
2015 Paine HA, Nathubhai A, Woon EC, Sunderland PT, Wood PJ, Mahon MF, Lloyd MD, Thompson AS, Haikarainen T, Narwal M, Lehtiö L, Threadgill MD. Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro. Bioorganic & Medicinal Chemistry. PMID 26189030 DOI: 10.1016/j.bmc.2015.06.061  0.419
2015 Toh JDW, Sun L, Lau LZM, Tan J, Low JJA, Tang CWQ, Cheong EJY, Tan MJH, Chen Y, Hong W, Gao YG, Woon ECY. A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO Chemical Science. 6: 112-122. DOI: 10.1039/c4sc02554g  0.303
2013 Yeoh KK, Chan MC, Thalhammer A, Demetriades M, Chowdhury R, Tian YM, Stolze I, McNeill LA, Lee MK, Woon EC, Mackeen MM, Kawamura A, Ratcliffe PJ, Mecinović J, Schofield CJ. Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion. Organic & Biomolecular Chemistry. 11: 732-45. PMID 23151668 DOI: 10.1039/C2Ob26648B  0.735
2012 Rose NR, Woon EC, Tumber A, Walport LJ, Chowdhury R, Li XS, King ON, Lejeune C, Ng SS, Krojer T, Chan MC, Rydzik AM, Hopkinson RJ, Che KH, Daniel M, et al. Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. Journal of Medicinal Chemistry. 55: 6639-43. PMID 22724510 DOI: 10.1021/Jm300677J  0.729
2012 Demetriades M, Leung IK, Chowdhury R, Chan MC, McDonough MA, Yeoh KK, Tian YM, Claridge TD, Ratcliffe PJ, Woon EC, Schofield CJ. Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors. Angewandte Chemie (International Ed. in English). 51: 6672-5. PMID 22639232 DOI: 10.1002/Anie.201202000  0.675
2012 Woon EC, Demetriades M, Bagg EA, Aik W, Krylova SM, Ma JH, Chan M, Walport LJ, Wegman DW, Dack KN, McDonough MA, Krylov SN, Schofield CJ. Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase. Journal of Medicinal Chemistry. 55: 2173-84. PMID 22263962 DOI: 10.1021/Jm201417E  0.645
2012 Woon EC, Tumber A, Kawamura A, Hillringhaus L, Ge W, Rose NR, Ma JH, Chan MC, Walport LJ, Che KH, Ng SS, Marsden BD, Oppermann U, McDonough MA, Schofield CJ. Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases. Angewandte Chemie (International Ed. in English). 51: 1631-4. PMID 22241642 DOI: 10.1002/Anie.201107833  0.705
2011 Woon EC, Zervosen A, Sauvage E, Simmons KJ, Zivec M, Inglis SR, Fishwick CW, Gobec S, Charlier P, Luxen A, Schofield CJ. Structure guided development of potent reversibly binding penicillin binding protein inhibitors. Acs Medicinal Chemistry Letters. 2: 219-23. PMID 24900305 DOI: 10.1021/Ml100260X  0.508
2011 Contreras-Martel C, Amoroso A, Woon EC, Zervosen A, Inglis S, Martins A, Verlaine O, Rydzik AM, Job V, Luxen A, Joris B, Schofield CJ, Dessen A. Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA). Acs Chemical Biology. 6: 943-51. PMID 21732689 DOI: 10.1021/Cb2001846  0.438
2011 Chowdhury R, Yeoh KK, Tian YM, Hillringhaus L, Bagg EA, Rose NR, Leung IK, Li XS, Woon EC, Yang M, McDonough MA, King ON, Clifton IJ, Klose RJ, Claridge TD, et al. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. Embo Reports. 12: 463-9. PMID 21460794 DOI: 10.1038/Embor.2011.43  0.623
2011 Sunderland PT, Woon EC, Dhami A, Bergin AB, Mahon MF, Wood PJ, Jones LA, Tully SR, Lloyd MD, Thompson AS, Javaid H, Martin NM, Threadgill MD. 5-Benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl)isoquinolin-1-ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2). Journal of Medicinal Chemistry. 54: 2049-59. PMID 21417348 DOI: 10.1021/jm1010918  0.374
2011 Chang KH, King ON, Tumber A, Woon EC, Heightman TD, McDonough MA, Schofield CJ, Rose NR. Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds. Chemmedchem. 6: 759-64. PMID 21412984 DOI: 10.1002/Cmdc.201100026  0.774
2010 Rose NR, Woon EC, Kingham GL, King ON, Mecinović J, Clifton IJ, Ng SS, Talib-Hardy J, Oppermann U, McDonough MA, Schofield CJ. Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. Journal of Medicinal Chemistry. 53: 1810-8. PMID 20088513 DOI: 10.1021/Jm901680B  0.778
2010 Inglis SR, Woon EC, Thompson AL, Schofield CJ. Observations on the deprotection of pinanediol and pinacol boronate esters via fluorinated intermediates. The Journal of Organic Chemistry. 75: 468-71. PMID 20014787 DOI: 10.1021/Jo901930V  0.326
2009 Inglis SR, Zervosen A, Woon EC, Gerards T, Teller N, Fischer DS, Luxen A, Schofield CJ. Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors. Journal of Medicinal Chemistry. 52: 6097-106. PMID 19731939 DOI: 10.1021/Jm9009718  0.463
2005 Woon EC, Threadgill MD. Poly(ADP-ribose)polymerase inhibition - where now? Current Medicinal Chemistry. 12: 2373-92. PMID 16181138 DOI: 10.2174/0929867054864778  0.348
Low-probability matches (unlikely to be authored by this person)
2018 Das M, Tianming Y, Jinghua D, Prasetya F, Yiming X, Wong K, Cheong A, Woon ECY. Multi-Protein Dynamic Combinatorial Chemistry: A Novel Strategy that Leads to Simultaneous Discovery of Subfamily-Selective Inhibitors for Nucleic Acid Demethylases FTO and ALKBH3. Chemistry, An Asian Journal. PMID 29917331 DOI: 10.1002/asia.201800729  0.265
2018 Das M, Yang T, Dong J, Prasetya F, Xie Y, Wong KHQ, Cheong A, Woon ECY. Cover Feature: Multiprotein Dynamic Combinatorial Chemistry: A Strategy for the Simultaneous Discovery of Subfamily-Selective Inhibitors for Nucleic Acid Demethylases FTO and ALKBH3 (Chem. Asian J. 19/2018) Chemistry - An Asian Journal. 13: 2740-2740. DOI: 10.1002/asia.201801029  0.262
2016 Zou S, Toh JD, Wong KH, Gao YG, Hong W, Woon EC. N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5. Scientific Reports. 6: 25677. PMID 27156733 DOI: 10.1038/srep25677  0.245
2013 Woon EC, Sunderland PT, Paine HA, Lloyd MD, Thompson AS, Threadgill MD. One-pot tandem Hurtley-retro-Claisen-cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs. Bioorganic & Medicinal Chemistry. 21: 5218-27. PMID 23849206 DOI: 10.1016/j.bmc.2013.06.031  0.232
2006 Woon ECY, Dhami A, Mahon MF, Threadgill MD. 5-Nitroisocoumarins from tandem Castro-Stephens coupling-6-endo-dig cyclisation of 2-iodo-3-nitrobenzoic acid and arylethynes and ring-closure of methyl 2-alkynyl-3-nitrobenzoates with electrophiles Tetrahedron. 62: 4829-4837. DOI: 10.1016/j.tet.2006.03.005  0.198
2007 Woon ECY, Dhami A, Mahon MF, Threadgill MD. Corrigendum to "5-Nitroisocoumarins from tandem Castro-Stephens coupling-6-endo-dig cyclisation of 2-iodo-3-nitrobenzoic acid and arylethynes and ring-closure of methyl 2-alkynyl-3-nitrobenzoates with electrophiles". [Tetrahedron 62 (2006) 4829] (DOI:10.1016/j.tet.2006.03.005) Tetrahedron. 63: 4191. DOI: 10.1016/j.tet.2007.03.014  0.19
2018 Cheong A, Low JJA, Lim A, Yen PM, Woon ECY. A fluorescent methylation-switchable probe for highly sensitive analysis of FTO -methyladenosine demethylase activity in cells. Chemical Science. 9: 7174-7185. PMID 30288236 DOI: 10.1039/c8sc02163e  0.186
2014 Woon ECY, Toh JDW. Antiobesity effects of natural products from an epigenetic perspective Studies in Natural Products Chemistry. 41: 161-193. DOI: 10.1016/B978-0-444-63294-4.00006-1  0.182
2016 Yang T, Cheong A, Mai X, Zou S, Woon EC. A methylation-switchable conformational probe for the sensitive and selective detection of RNA demethylase activity. Chemical Communications (Cambridge, England). PMID 27074833 DOI: 10.1039/c6cc01045h  0.176
2013 Singh N, Halliday AC, Thomas JM, Kuznetsova OV, Baldwin R, Woon EC, Aley PK, Antoniadou I, Sharp T, Vasudevan SR, Churchill GC. A safe lithium mimetic for bipolar disorder. Nature Communications. 4: 1332. PMID 23299882 DOI: 10.1038/Ncomms2320  0.164
2019 Yang T, Low JJA, Woon ECY. A general strategy exploiting m5C duplex-remodelling effect for selective detection of RNA and DNA m5C methyltransferase activity in cells. Nucleic Acids Research. PMID 31691820 DOI: 10.1093/nar/gkz1047  0.143
2007 Woon EC, Arcieri M, Wilderspin AF, Malkinson JP, Searcey M. Solid-phase synthesis of chlorofusin analogues. The Journal of Organic Chemistry. 72: 5146-51. PMID 17559272 DOI: 10.1021/jo070450a  0.141
2002 Wong SM, Shah B, Shah P, Butt IC, Woon ECY, Wright JA, Thompson AS, Upton C, Threadgill MD. A new synthesis of 'push-pull' naphthalenes by condensation of nitro-2-methylbenzoate esters with dimethylacetamide dimethyl acetal Tetrahedron Letters. 43: 2299-2302. DOI: 10.1016/S0040-4039(02)00228-9  0.109
1985 Woon EY. n-connectedness in pure 2-complexes Israel Journal of Mathematics. 52: 177-192. DOI: 10.1007/BF02786514  0.105
2017 Goh WJ, Lee CK, Zou S, Woon EC, Czarny B, Pastorin G. Doxorubicin-loaded cell-derived nanovesicles: an alternative targeted approach for anti-tumor therapy. International Journal of Nanomedicine. 12: 2759-2767. PMID 28435256 DOI: 10.2147/IJN.S131786  0.1
2024 Shao Z, King-Gee Tam K, Vaishnav APK, Woon ECY, James Mason A, Fung Chow S, Cheong Yam W, Lam JKW. Synergistic combination of antimicrobial peptide and isoniazid as inhalable dry powder formulation against multi-drug resistant tuberculosis. International Journal of Pharmaceutics. 123960. PMID 38447778 DOI: 10.1016/j.ijpharm.2024.123960  0.073
2016 Lim A, Zhou J, Sinha RA, Singh BK, Ghosh S, Lim KH, Kah-Hoe Chow P, Woon EC, Yen PM. Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity. Biochemical and Biophysical Research Communications. PMID 27651333 DOI: 10.1016/j.bbrc.2016.09.086  0.067
2006 Woon ECY, Dhami A, Sunderland PT, Chalkley DA, Threadgill MD. Reductive cyclisation of 2-cyanomethyl-3-nitrobenzoates Letters in Organic Chemistry. 3: 619-621. DOI: 10.1002/chin.200713153  0.064
2015 Wallace MW, Hood AVS, Woon EMS, Giddings JA, Fromhold TA. The cryogenian balcanoona reef complexes of the northern flinders ranges: Implications for neoproterozoic ocean chemistry Palaeogeography, Palaeoclimatology, Palaeoecology. 417: 320-336. DOI: 10.1016/j.palaeo.2014.09.028  0.059
2020 Ou YH, Zou S, Goh WJ, Chong SY, Venkatesan G, Wacker MG, Storm G, Wang JW, Czarny B, Pastorin G, Woon ECY. Micro cell vesicle technology (mCVT): a novel hybrid system of gene delivery for hard-to-transfect (HTT) cells. Nanoscale. PMID 32857097 DOI: 10.1039/d0nr03784b  0.035
2014 Wallace MW, Hood AVS, Woon EMS, Hoffmann KH, Reed CP. Enigmatic chambered structures in Cryogenian reefs: The oldest sponge-grade organisms? Precambrian Research. 255: 109-123. DOI: 10.1016/j.precamres.2014.09.020  0.034
2009 Giddings JA, Wallace MW, Woon EMS. Interglacial carbonates of the Cryogenian Umberatana Group, northern Flinders Ranges, South Australia Australian Journal of Earth Sciences. 56: 907-925. DOI: 10.1080/08120090903005378  0.022
2003 Enoch S, Woon E, Blair SD. Thromboprophylaxis can be omitted in selected patients undergoing varicose vein surgery and hernia repair. The British Journal of Surgery. 90: 818-20. PMID 12854106 DOI: 10.1002/bjs.4185  0.02
1989 Woon EY. Chinese arms sales and US - China military relations Asian Survey. 29: 601-618.  0.01
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