Melissa A. Fath, Ph.D. - Publications

Affiliations: 
2001 University of Iowa, Iowa City, IA 
Area:
Heparin

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Musser ML, Mahaffey AL, Fath MA, Buettner GR, Wagner BA, Schneider BK, Seo YJ, Mochel JP, Johannes CM. Cytotoxicity and Pharmacokinetic Evaluation of Pharmacological Ascorbate in Dogs. Frontiers in Veterinary Science. 6: 385. PMID 31788483 DOI: 10.3389/Fvets.2019.00385  0.316
2018 Luo M, Shang L, Brooks MD, Jiagge E, Zhu Y, Buschhaus JM, Conley S, Fath MA, Davis A, Gheordunescu E, Wang Y, Harouaka R, Lozier A, Triner D, McDermott S, et al. Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. Cell Metabolism. 28: 69-86.e6. PMID 29972798 DOI: 10.1016/J.Cmet.2018.06.006  0.33
2018 Luo M, Shang L, Brooks M, Jiagge E, Zhu Y, Conley S, Fath M, Harouaka R, Merajver S, Spitz, Wicha. Abstract P1-02-09: Targeting breast cancer stem cell state equilibrium through modulation of redox signaling Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P1-02-09  0.337
2018 Ma D, Anderson C, Rodmann SN, Follmer K, Buranasudja V, Bodeker K, Parkhurst JR, McCormack M, Davis A, Spitz DR, Buatti J, Allen BG, Fath MA. Abstract LB-252: Ketogenic diet with concurrent chemoradiation in head and neck squamous cell carcinoma: Pre-clinical and phase I trial results Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-252  0.364
2018 Sciegienka S, Rodman S, Tomanek-Chalkley A, Falls KC, Spitz DR, Fath MA. Abstract 3219: Sensitizing hypoxic small cell lung cancer cells to radiation and hydrogen peroxide-producing agents using CuATSM Tumor Biology. DOI: 10.1158/1538-7445.Am2018-3219  0.34
2017 Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biology. 14: 82-87. PMID 28886484 DOI: 10.1016/J.Redox.2017.08.017  0.321
2017 Zahra A, Fath MA, Opat E, Mapuskar KA, Bhatia SK, Ma DC, Iii SNR, Snyders TP, Chenard CA, Eichenberger-Gilmore JM, Bodeker KL, Ahmann L, Smith BJ, Vollstedt SA, Brown HA, et al. Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer: The University of Iowa Experience of Two Phase 1 Clinical Trials. Radiation Research. PMID 28437190 DOI: 10.1667/Rr14668.1  0.373
2017 Sciegienka SJ, Solst SR, Falls KC, Schoenfeld JD, Klinger AR, Ross NL, Rodman SN, Spitz DR, Fath MA. D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H2O2-mediated oxidative stress. Free Radical Biology & Medicine. PMID 28389407 DOI: 10.1016/J.Freeradbiomed.2017.04.001  0.414
2017 Solst SR, Rodman SN, Fath MA, Taylor EB, Spitz DR. Inhibition of Mitochondrial Pyruvate Transport Selectively Sensitizes Cancer Cells to Metabolic Oxidative Stress Free Radical Biology and Medicine. 112: 102. DOI: 10.1016/J.Freeradbiomed.2017.10.154  0.401
2017 Falls K, Gui K, Anderson M, Rodman S, Solst S, Fath M, McCormick M, Spitz D. Disulfiram causes Selective Hypoxic Cancer Cell Toxicity and Radio-chemo-sensitization via Redox Cycling of Copper and O 2 •‒ mediated Oxidative Stress Free Radical Biology and Medicine. 112: 88. DOI: 10.1016/J.Freeradbiomed.2017.10.128  0.365
2016 Rodman SN, Spence JM, Ronnfeldt TJ, Zhu Y, Solst SR, O'Neill RA, Allen BG, Guan X, Spitz DR, Fath MA. Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism. Radiation Research. PMID 27643875 DOI: 10.1667/Rr14463.1  0.386
2015 Hrabe JE, O'Leary BR, Fath MA, Rodman SN, Button AM, Domann FE, Spitz DR, Mezhir JJ. Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells. Redox Biology. 5: 319-327. PMID 26114584 DOI: 10.1016/J.Redox.2015.06.004  0.391
2015 Li L, Fath MA, Scarbrough PM, Watson WH, Spitz DR. Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer. Redox Biology. 4: 127-35. PMID 25560241 DOI: 10.1016/J.Redox.2014.12.001  0.399
2015 Ma DC, Rodman SN, Buatti JM, Anderson C, Allen BG, Spitz DR, Fath MA. Abstract 1177: Ketogenic diet sensitizes FaDu human head and neck cancer xenografts to cisplatin as well as ionizing radiation combined with cetuximab Cancer Research. 75: 1177-1177. DOI: 10.1158/1538-7445.Am2015-1177  0.38
2014 Allen BG, Bhatia SK, Anderson CM, Eichenberger-Gilmore JM, Sibenaller ZA, Mapuskar KA, Schoenfeld JD, Buatti JM, Spitz DR, Fath MA. Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism. Redox Biology. 2: 963-970. PMID 25460731 DOI: 10.1016/J.Redox.2014.08.002  0.39
2014 Wegman-Points LJ, Teoh-Fitzgerald ML, Mao G, Zhu Y, Fath MA, Spitz DR, Domann FE. Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population. Redox Biology. 2: 847-54. PMID 25009786 DOI: 10.1016/J.Redox.2014.06.006  0.377
2013 Allen BG, Bhatia SK, Buatti JM, Brandt KE, Lindholm KE, Button AM, Szweda LI, Smith BJ, Spitz DR, Fath MA. Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3905-13. PMID 23743570 DOI: 10.1158/1078-0432.Ccr-12-0287  0.366
2013 Conley SJ, Baker T, Theisen R, Gheordunescu E, Zhu Y, Aykin-Burns N, Fath M, Spitz D, Wicha M. Abstract 3729: Targeting breast cancer stem cells via oxidative stress with inhibitors of hydroperoxide metabolism and decyl-triphenylphosphonium. Cancer Research. 73: 3729-3729. DOI: 10.1158/1538-7445.Am2013-3729  0.376
2012 Rodman SN, Zhu Y, Ronnfeldt TJ, Wilke WW, Allen BG, Spitz DR, Fath MA. Abstract 1470: Enhancing radiation therapy by simultaneous inhibition of thioredoxin- and glutathione-dependent metabolism Cancer Research. 72: 1470-1470. DOI: 10.1158/1538-7445.Am2012-1470  0.423
2011 Fath MA, Ahmad IM, Smith CJ, Spence J, Spitz DR. Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6206-17. PMID 21844013 DOI: 10.1158/1078-0432.Ccr-11-0736  0.377
2011 Allen B, Szweda L, Buatti J, Bhatia S, Spitz D, Fath M. Ketogenic Diets Enhance Lung Cancer Reponse To Therapy Free Radical Biology and Medicine. 51: S82. DOI: 10.1016/J.Freeradbiomed.2011.10.386  0.304
2009 Simons AL, Parsons AD, Foster KA, Orcutt KP, Fath MA, Spitz DR. Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells. Journal of Oncology. 2009: 519563. PMID 19746172 DOI: 10.1155/2009/519563  0.38
2009 Fath MA, Diers AR, Aykin-Burns N, Simons AL, Hua L, Spitz DR. Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells. Cancer Biology & Therapy. 8: 1228-36. PMID 19411865 DOI: 10.4161/Cbt.8.13.8631  0.387
2002 Zhang F, Fath M, Marks R, Linhardt RJ. A highly stable covalent conjugated heparin biochip for heparin-protein interaction studies Analytical Biochemistry. 304: 271-273. PMID 12009707 DOI: 10.1006/Abio.2002.5617  0.525
2000 Kilpeläinen I, Kaksonen M, Kinnunen T, Avikainen H, Fath M, Linhardt RJ, Raulo E, Rauvala H. Heparin-binding growth-associated molecule contains two heparin-binding β-sheet domains that are homologous to the thrombospondin type I repeat Journal of Biological Chemistry. 275: 13564-13570. PMID 10788472 DOI: 10.1074/Jbc.275.18.13564  0.357
1999 Fath M, Vandernoot V, Kilpeläinen I, Kinnunen T, Rauvala H, Linhardt RJ. Interaction of soluble and surface-bound heparin binding growth-associated molecule with heparin Febs Letters. 454: 105-108. PMID 10413105 DOI: 10.1016/S0014-5793(99)00785-1  0.584
1998 Fath MA, Wu X, Hileman RE, Linhardt RJ, Kashem MA, Nelson RM, Wright CD, Abraham WM. Interaction of secretory leukocyte protease inhibitor with heparin inhibits proteases involved in asthma. The Journal of Biological Chemistry. 273: 13563-9. PMID 9593692 DOI: 10.1074/Jbc.273.22.13563  0.479
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