Dieter Seebach, Ph.D. - Publications

Affiliations: 
Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 
Area:
synthetic methods
Website:
http://www.loc.ethz.ch/people/emerit/Seebach

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Year Citation  Score
2019 Grogg M, Hilvert D, Beck AK, Seebach D. Syntheses of Cyanophycin Segments for Investigations of Cell-Penetration Synthesis. 51: 31-39. DOI: 10.1055/S-0037-1610202  0.384
2017 Seebach D. What I Have Learned from Jack Dunitz Israel Journal of Chemistry. 57: 55-65. DOI: 10.1002/Ijch.201600010  0.335
2015 Kolesinska B, Eyer K, Robinson T, Dittrich PS, Beck AK, Seebach D, Walde P. Interaction of β(3) /β(2) -peptides, consisting of Val-Ala-Leu segments, with POPC giant unilamellar vesicles (GUVs) and white blood cancer cells (U937)--a new type of cell-penetrating peptides, and a surprising chain-length dependence of their vesicle- and cell-lysing activity. Chemistry & Biodiversity. 12: 697-732. PMID 26010661 DOI: 10.1002/Cbdv.201500085  0.316
2015 Purkayastha N, Capone S, Beck AK, Seebach D, Leeds J, Thompson K, Moser HE. Antibacterial activity of enrofloxacin and ciprofloxacin derivatives of β-octaarginine. Chemistry & Biodiversity. 12: 179-93. PMID 25676502 DOI: 10.1002/Cbdv.201400456  0.322
2015 Meyer D, Marti R, Seebach D. Scalable Enantioselective Synthesis of Fmoc-β2-Serine and Fmoc-β2-Threonine by an Organocatalytic Mannich Reaction European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.201500636  0.369
2014 Schaab C, Kling RC, Einsiedel J, Hübner H, Clark T, Seebach D, Gmeiner P. Structure-based evolution of subtype-selective neurotensin receptor ligands. Chemistryopen. 3: 206-18. PMID 25478316 DOI: 10.1002/Open.201402031  0.304
2014 Hayashi Y, Okamura D, Yamazaki T, Ameda Y, Gotoh H, Tsuzuki S, Uchimaru T, Seebach D. A theoretical and experimental study of the effects of silyl substituents in enantioselective reactions catalyzed by diphenylprolinol silyl ether. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 17077-88. PMID 25348681 DOI: 10.1002/Chem.201403514  0.493
2014 Seebach D. Joy and flustration with organofluorine compounds - a fluorous autobiography. Chimia. 68: 348-55. PMID 25198744 DOI: 10.2533/Chimia.2014.348  0.387
2014 Grošelj U, Beck A, Schweizer WB, Seebach D. Preparation and structures of 2-substituted 5-benzyl-3-methylimidazolidin- 4-one-derived iminium salts, reactive intermediates in organocatalytic transformations involving α,β-unsaturated aldehydes Helvetica Chimica Acta. 97: 751-796. DOI: 10.1002/Hlca.201400110  0.359
2013 Seebach D. A journey from the pool of chiral synthetic building blocks to cell-penetrating peptides, to a novel type of enzyme - and back. Chimia. 67: 844-50. PMID 24594324 DOI: 10.2533/Chimia.2013.844  0.35
2013 Sparr C, Purkayastha N, Yoshinari T, Seebach D, Maschauer S, Prante O, Hübner H, Gmeiner P, Kolesinska B, Cescato R, Waser B, Reubi JC. Syntheses, receptor bindings, in vitro and in vivo stabilities and biodistributions of DOTA-neurotensin(8-13) derivatives containing β-amino acid residues - a lesson about the importance of animal experiments. Chemistry & Biodiversity. 10: 2101-21. PMID 24327436 DOI: 10.1002/Cbdv.201300331  0.322
2013 Purkayastha N, Eyer K, Robinson T, Dittrich PS, Beck AK, Seebach D, Kolesinska B, Cadalbert R. Enantiomeric and diastereoisomeric (mixed) L/ D-octaarginine derivatives - a simple way of modulating the properties of cell-penetrating peptides. Chemistry & Biodiversity. 10: 1165-84. PMID 23847063 DOI: 10.1002/Cbdv.201300180  0.302
2013 Kolesinska B, Podwysocka DJ, Rueping MA, Seebach D, Kamena F, Walde P, Sauer M, Windschiegl B, Meyer-Ács M, Vor der Brüggen M, Giehring S. Permeation through phospholipid bilayers, skin-cell penetration, plasma stability, and CD spectra of α- and β-oligoproline derivatives. Chemistry & Biodiversity. 10: 1-38. PMID 23341206 DOI: 10.1002/Cbdv.201200393  0.528
2013 Grošelj U, Podlipnik C, Bezenšek J, Svete J, Stanovnik B, Seebach D. Reversal of the stereochemical course of 1-methyl-1H-indole addition to cinnamaldehyde with cis-5-benzyl-(2-fluoromethyl)-2,3-dimethylimidazolidin-4- ones as catalysts - A puzzling 'fluorine effect': Preliminary communication Helvetica Chimica Acta. 96: 1815-1821. DOI: 10.1002/Hlca.201300332  0.313
2013 Seebach D, Sun X, Ebert MO, Schweizer WB, Purkayastha N, Beck AK, Duschmalé J, Wennemers H, Mukaiyama T, Benohoud M, Hayashi Y, Reiher M. Stoichiometric reactions of enamines derived from diphenylprolinol silyl ethers with nitro olefins and lessons for the corresponding organocatalytic conversions - A survey Helvetica Chimica Acta. 96: 799-852. DOI: 10.1002/Hlca.201300079  0.541
2012 Merz T, Heck T, Geueke B, Mittl PR, Briand C, Seebach D, Kohler HP, Grütter MG. Autoproteolytic and catalytic mechanisms for the β-aminopeptidase BapA--a member of the Ntn hydrolase family. Structure (London, England : 1993). 20: 1850-60. PMID 22980995 DOI: 10.1016/J.Str.2012.07.017  0.322
2012 Heck T, Merz T, Reimer A, Seebach D, Rentsch D, Briand C, Grütter MG, Kohler HP, Geueke B. Crystal structures of BapA complexes with β-lactam-derived inhibitors illustrate substrate specificity and enantioselectivity of β-aminopeptidases. Chembiochem : a European Journal of Chemical Biology. 13: 2137-45. PMID 22961926 DOI: 10.1002/Cbic.201200393  0.344
2012 Niggli DA, Ebert MO, Lin Z, Seebach D, van Gunsteren WF. Helical content of a β(3)-octapeptide in methanol: molecular dynamics simulations explain a seeming discrepancy between conclusions derived from CD and NMR data. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 586-93. PMID 22162155 DOI: 10.1002/Chem.201102667  0.302
2012 Seebach D, Sun X, Sparr C, Ebert MO, Schweizer WB, Beck AK. 1,2-oxazine N-oxides as catalyst resting states in michael additions of aldehydes to nitro olefins organocatalyzed by α,α-diphenylprolinol trimethylsilyl ether: Preliminary communication Helvetica Chimica Acta. 95: 1064-1078. DOI: 10.1002/Hlca.201200283  0.335
2012 Seebach D, Beck AK, Bichsel HU, Pichota A, Sparr C, Wünsch R, Schweizer WB. Preparation and characterization of new C 2- and C 1-symmetric nitrogen, oxygen, phosphorous, and sulfur derivatives and analogs of TADDOL. part III Helvetica Chimica Acta. 95: 1303-1324. DOI: 10.1002/Hlca.201200146  0.35
2011 Charkoudian LK, Liu CW, Capone S, Kapur S, Cane DE, Togni A, Seebach D, Khosla C. Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase. Protein Science : a Publication of the Protein Society. 20: 1244-55. PMID 21563224 DOI: 10.1002/Pro.652  0.467
2011 Seebach D, Lukaszuk A, Patora-Komisarska K, Podwysocka D, Gardiner J, Ebert MO, Reubi JC, Cescato R, Waser B, Gmeiner P, Hübner H, Rougeot C. On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY. Chemistry & Biodiversity. 8: 711-39. PMID 21560227 DOI: 10.1002/Cbdv.201100093  0.341
2011 Kamena F, Monnanda B, Makou D, Capone S, Patora-Komisarska K, Seebach D. On the mechanism of eukaryotic cell penetration by α- and β-oligoarginines--targeting infected erythrocytes. Chemistry & Biodiversity. 8: 1-12. PMID 21259419 DOI: 10.1002/Cbdv.201000318  0.303
2011 Seebach D. Generation of secondary, tertiary, and quaternary centers by geminal disubstitution of carbonyl oxygens. Angewandte Chemie (International Ed. in English). 50: 96-101. PMID 21154539 DOI: 10.1002/Anie.201003823  0.31
2011 Yoshinari T, Gessier F, Noti C, Beck AK, Seebach D. Stereoselective preparation of 3-amino-2-fluoro carboxylic acid derivatives, and their incorporation in tetrahydropyrimidin-4(1H)-ones, and in open-chain and cyclic β-peptides Helvetica Chimica Acta. 94: 1908-1942. DOI: 10.1002/Hlca.201100340  0.417
2011 Patora-Komisarska K, Benohoud M, Ishikawa H, Seebach D, Hayashi Y. Organocatalyzed michael addition of aldehydes to nitro alkenes - Generally accepted mechanism revisited and revised Helvetica Chimica Acta. 94: 719-745. DOI: 10.1002/Hlca.201100122  0.543
2011 Jaun B, Seebach D, Mathad RI. Note: Helix or no helix of β-peptides containing β 3hAla(αF) residues? Helvetica Chimica Acta. 94: 355-361. DOI: 10.1002/Hlca.201100023  0.348
2011 Patora-Komisarska K, Jadwiga Podwysocka D, Seebach D. Preparation of the β 2-homoselenocysteine derivatives Fmoc-(S)-β 2hSec(PMB)-OH and Boc-(S)-β 2hSec(PMB)- OH for solution and solid-phase peptide synthesis Helvetica Chimica Acta. 94: 1-17. DOI: 10.1002/Hlca.201000409  0.393
2010 Heck T, Reimer A, Seebach D, Gardiner J, Deniau G, Lukaszuk A, Kohler HP, Geueke B. Beta-aminopeptidase-catalyzed biotransformations of beta(2)-dipeptides: kinetic resolution and enzymatic coupling. Chembiochem : a European Journal of Chemical Biology. 11: 1129-36. PMID 20340152 DOI: 10.1002/Cbic.200900757  0.316
2010 Seebach D, Gilmour R, Grošelj U, Deniau G, Sparr C, Ebert MO, Beck AK, McCusker LB, Šišak D, Uchimaru T. Stereochemical models for discussing additions to α,β- unsaturated aldehydes organocatalyzed by diarylprolinol or imidazolidinone derivatives - Is there an '(E)/(Z)-dilemma'? Helvetica Chimica Acta. 93: 603-634. DOI: 10.1002/Hlca.201000069  0.336
2010 Sprecher H, Pletscher S, Möri M, Marti R, Gaul C, Patora-Komisarska K, Otchertianova E, Beck AK, Seebach D. Applications of the chiral auxiliaries DIOZ and TRIOZ for conjugate additions and comparison with other auxiliaries Helvetica Chimica Acta. 93: 90-110. DOI: 10.1002/Hlca.200900385  0.384
2010 Seebach D, Grošelj U, Schweizer WB, Grimme S, Mück-Lichtenfeld C. Experimental and theoretical conformational analysis of 5-benzylimidazolidin-4-one derivatives - A 'playground' for studying dispersion interactions and a 'windshield-wiper' effect in organocatalysis Helvetica Chimica Acta. 93: 1-16. DOI: 10.1002/Hlca.200900376  0.329
2010 Seebach D, Brenner M, Rueping M, Jaun B. ChemInform Abstract: γ2-, γ3-, and γ2,3,4-Amino Acids, Coupling to γ-Hexapeptides: CD Spectra, NMR Solution and X-Ray Crystal Structures of γ-Peptides. Cheminform. 33: no-no. DOI: 10.1002/chin.200227223  0.467
2010 MATTHEWS JL, BRAUN C, GUIBOURDENCHE C, OVERHAND M, SEEBACH D. ChemInform Abstract: Preparation of Enantiopure β-Amino Acids from α-Amino Acids Using the Arndt-Eistert Homologation Cheminform. 28: no-no. DOI: 10.1002/chin.199746324  0.589
2010 STUDER A, HINTERMANN T, SEEBACH D. ChemInform Abstract: Synthesis and First Applications of a New Chiral Auxiliary (tert-Butyl 2-(tert-Butyl)-5,5-dimethyl-4-oxoimidazolidine-1-carboxylate) (V). Cheminform. 26: no-no. DOI: 10.1002/chin.199547157  0.44
2010 Heck T, Makam VS, Lutz J, Blank LM, Schmid A, Seebach D, Kohler HPE, Geuekea B. Kinetic analysis of L-carnosine formation by β-aminopeptidases Advanced Synthesis and Catalysis. 352: 407-415. DOI: 10.1002/Adsc.200900697  0.336
2009 Heck T, Seebach D, Osswald S, Ter Wiel MK, Kohler HP, Geueke B. Kinetic resolution of aliphatic beta-amino acid amides by beta-aminopeptidases. Chembiochem : a European Journal of Chemical Biology. 10: 1558-61. PMID 19449346 DOI: 10.1002/Cbic.200900184  0.326
2009 Seebach D, Beck AK, Capone S, Deniau G, Grošelj U, Zass E. Enantioselective preparation of β2-amino acid derivatives for β-Peptide synthesis Synthesis. 1-32. DOI: 10.1055/S-0028-1087490  0.39
2009 Heck T, Geueke B, Seebach D, Osswald S, Ter Wiel M, Kohler H. β-Aminopeptidases: enzymatic degradation and synthesis of β-amino acid containing peptides and kinetic resolution of β-amino acid amides New Biotechnology. 25: S62. DOI: 10.1016/J.Nbt.2009.06.291  0.353
2009 Gardiner J, Mathad RI, Jaun B, Schreiber JV, Flögel O, Seebach D. β-peptide conjugates: Syntheses and CD and NMR investigations of β/α-chimeric peptides, of a DPA-β-decapeptide, and of a PEGylated β-heptapeptide Helvetica Chimica Acta. 92: 2698-2721. DOI: 10.1002/Hlca.200900325  0.354
2009 Ebert MO, Gardiner J, Ballet S, Abell AD, Seebach D. Synthesis and high-resolution NMR structure of a β3- octapeptide with and without a tether introduced by olefin metathesis Helvetica Chimica Acta. 92: 2643-2658. DOI: 10.1002/Hlca.200900311  0.357
2009 Deniau G, Seebach D. Preparation of N-Fmoc-protected (S)-5-amino-4,4-difluoro-7-methyloctanoic acid, a possible dipeptide isostere Helvetica Chimica Acta. 92: 1720-1728. DOI: 10.1002/Hlca.200900215  0.35
2009 Grošelj U, Seebach D, Badine DM, Schweizer WB, Beck AK, Krossing I, Klose P, Hayashi Y, Uchimaru T. Structures of the reactive intermediates in organocatalysis with diarylprolinol ethers Helvetica Chimica Acta. 92: 1225-1259. DOI: 10.1002/Hlca.200900179  0.532
2009 Grošelj U, Schweizer WB, Ebert MO, Seebach D. 5-benzyl-3-methylimidazolidin-4-one-derived reactive intermediates of organocatalysis - A comforting resemblance of X-ray, NMR, and DFT solid-phase, liquid-phase, and gas-phase structures Helvetica Chimica Acta. 92: 1-13. DOI: 10.1002/Hlca.200800432  0.322
2008 David R, Günther R, Baumann L, Lühmann T, Seebach D, Hofmann HJ, Beck-Sickinger AG. Artificial chemokines: combining chemistry and molecular biology for the elucidation of interleukin-8 functionality. Journal of the American Chemical Society. 130: 15311-7. PMID 18942784 DOI: 10.1021/Ja802453X  0.303
2008 Seebach D, Gardiner J. Beta-peptidic peptidomimetics. Accounts of Chemical Research. 41: 1366-75. PMID 18578513 DOI: 10.1021/Ar700263G  0.318
2008 Caponea S, Kieltschb I, Flögela O, Lelaisa G, Togni A, Seebach D. Electrophilic S-trifluoromethylation of cysteine side chains in α- and β-peptides: Isolation of trifluoromethylated sandostatin® (octreotide) derivatives Helvetica Chimica Acta. 91: 2035-2056. DOI: 10.1002/Hlca.200890217  0.382
2008 Seebach D, Grošelj U, Badine DM, Schweizer WB, Beck AK. Isolation and X-ray structures of reactive intermediates of organocatalysis with diphenylprolinol ethers and with imidazolidinones a survey and comparison with computed structures and with 1-acyl-imidazolidinones: The 1,5-repulsion and the geminal-diaryl effect at work Helvetica Chimica Acta. 91: 1999-2034. DOI: 10.1002/Hlca.200890216  0.326
2008 Seebach D, Dubost E, Mathad RI, Jaun B, Limbach M, Löweneck M, Flögel O, Gardiner J, Capone S, Beck AK, Widmer H, Langenegger D, Monna D, Hoyer D. New open-chain and cyclic tetrapeptides, consisting of α-, β2-, and β3-amino-acid residues, as somatostatin mimics - A survey Helvetica Chimica Acta. 91: 1736-1786. DOI: 10.1002/Hlca.200890190  0.362
2008 Müller-Hartwieg JCD, La Vecchia L, Meyer H, Beck AK, Seebach D. (R)-2-(benzyloxycarbonylamino-methyl)-3-phenylpropanoic acid (Z-β2hPHE-OH): Preparation of A β2-amino acid with the auxiliary dioz Organic Syntheses. 85: 295-306. DOI: 10.1002/0471264229.Os085.30  0.373
2008 Meyer H, Beck AK, Sebesta R, Seebach D. Benzyl isopropoxymethyl carbamate - An aminomethylating reagent for mannich reactions of titanium enolates Organic Syntheses. 85: 287-294. DOI: 10.1002/0471264229.Os085.29  0.332
2007 Hubatsch I, Arvidsson PI, Seebach D, Luthman K, Artursson P. Beta- and gamma-di- and tripeptides as potential substrates for the oligopeptide transporter hPepT1. Journal of Medicinal Chemistry. 50: 5238-42. PMID 17887660 DOI: 10.1021/Jm070148U  0.59
2007 Mathad RI, Jaun B, Flögel O, Gardiner J, Löweneck M, Codée JDC, Seeberger PH, Seebach D, Edmonds MK, Graichen FHM, Abell AD. NMR-solution structures of fluoro-substituted β-peptides: A 3 14-helix and a hairpin turn. The first case of a 90° O=C-C-F dihedral angle in an α-fluoro-amide group Helvetica Chimica Acta. 90: 2251-2273. DOI: 10.1002/Hlca.200790235  0.36
2007 Flögel O, Casi G, Hilvert D, Seebach D. Preparation of the β3-homoselenocysteine derivatives Fmoc-β3hSec(PMB)-OH and Boc-β3hSec(PMB)-OH for solution and solid-phase-peptide synthesis and selenoligation Helvetica Chimica Acta. 90: 1651-1666. DOI: 10.1002/Hlca.200790171  0.387
2007 Seebach D, Beck AK, Badine DM, Limbach M, Eschenmoser A, Treasurywala AM, Hobi R, Prikoszovich W, Linder B. Are oxazolidinones really unproductive, parasitic species in proline catalysis? - Thoughts and experiments pointing to an alternative view Helvetica Chimica Acta. 90: 425-471. DOI: 10.1002/Hlca.200790050  0.377
2007 Seebach D, Beck AK, Heckel A. TADDOL and its derivatives - Our dream of universal chiral auxiliaries Essays in Contemporary Chemistry: From Molecular Structure Towards Biology. 283-306. DOI: 10.1002/9783906390451.ch7  0.529
2006 Heck T, Limbach M, Geueke B, Zacharias M, Gardiner J, Kohler HP, Seebach D. Enzymatic degradation of beta- and mixed alpha,beta-oligopeptides. Chemistry & Biodiversity. 3: 1325-48. PMID 17193247 DOI: 10.1002/Cbdv.200690136  0.302
2006 Geueke B, Heck T, Limbach M, Nesatyy V, Seebach D, Kohler HP. Bacterial beta-peptidyl aminopeptidases with unique substrate specificities for beta-oligopeptides and mixed beta,alpha-oligopeptides. The Febs Journal. 273: 5261-72. PMID 17064315 DOI: 10.1111/J.1742-4658.2006.05519.X  0.305
2006 Wezenberg SJ, Metselaar GA, Rowan AE, Cornelissen JJ, Seebach D, Nolte RJ. Synthesis, characterization, and folding behavior of beta-amino acid derived polyisocyanides. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 2778-86. PMID 16419142 DOI: 10.1002/Chem.200501042  0.34
2006 Seebach D, Hook DF, Glättli A. Helices and other secondary structures of beta- and gamma-peptides. Biopolymers. 84: 23-37. PMID 16235225 DOI: 10.1002/Bip.20391  0.314
2006 Hoffmann T, Seebach D. Preparation of 12- and 16-Membered Macrolactones (Oligolides) from (S)-Malic Acid - Low Molecular-Mass Analogs of the Biopolymer Poly[(S)-Malic Acid] (PMA) Liebigs Annalen. 1996: 1277-1282. DOI: 10.1002/Jlac.199619960806  0.353
2006 Bezencon O, Seebach D. Alkylations of Chiral Imidazolidinones Derived from Di‐ and Triglycine and Attempts at Cyclisations to Give Cycloisodityrosines Liebigs Annalen. 1996: 1259-1276. DOI: 10.1002/Jlac.199619960805  0.405
2006 Guibourdenche C, Podlech J, Seebach D. Selective Acylations of Multifunctional Nucleophiles, Including Carbohydrates and Nucleosides, with Intermediates Generated by Wolff Rearrangement of Amino Acid Derived Diazo Ketones: Preparation of β-Amino Acid Derivatives Liebigs Annalen. 1996: 1121-1129. DOI: 10.1002/Jlac.199619960710  0.407
2006 Namoto K, Gardiner J, Kimmerlin T, Seebach D. Investigation of the interactions of β-peptides with DNA duplexes by circular dichroism spectroscopy Helvetica Chimica Acta. 89: 3087-3103. DOI: 10.1002/Hlca.200690277  0.307
2006 Seebach D, Jaun B, Sebesta R, Mathad RI, Flögel O, Limbach M, Sellner H, Cottens S. Synthesis, and helix or hairpin-turn secondary structures of 'mixed' α/β-peptides consisting of residues with proteinogenic side chains and of 2-amino-2-methylpropanoic acid (Aib) Helvetica Chimica Acta. 89: 1801-1825. DOI: 10.1002/Hlca.200690176  0.394
2006 Limbach M, Löweneck M, Schreiber JV, Frackenpohl J, Seebach D, Billich A. Synthesis of β3-homophenylalanine-derived amino acids and peptides by Suzuki coupling in solution and on solid support Helvetica Chimica Acta. 89: 1427-1441. DOI: 10.1002/Hlca.200690143  0.365
2006 Lelais G, Seebach D, Jaun B, Mathad RI, Flögel O, Rossi F, Campo M, Wortmann A. β‐Peptidic Secondary Structures Fortified and Enforced by Zn2+ Complexation – On the Way to β‐Peptidic Zinc Fingers? Helvetica Chimica Acta. 89: 361-403. DOI: 10.1002/Hlca.200690040  0.342
2006 Flögel O, Codée JDC, Seebach D, Seeberger PH. Synthese von β-Peptiden im Mikroreaktor Angewandte Chemie. 118: 7157-7160. DOI: 10.1002/Ange.200602167  0.305
2005 Arvidsson PI, Ryder NS, Weiss HM, Hook DF, Escalante J, Seebach D. Exploring the antibacterial and hemolytic activity of shorter- and longer-chain beta-, alpha,beta-, and gamma-peptides, and of beta-peptides from beta2-3-aza- and beta3-2-methylidene-amino acids bearing proteinogenic side chains--a survey. Chemistry & Biodiversity. 2: 401-20. PMID 17191989 DOI: 10.1002/Cbdv.200590020  0.609
2005 Glättli A, Daura X, Bindschädler P, Jaun B, Mahajan YR, Mathad RI, Rueping M, Seebach D, van Gunsteren WF. On the influence of charged side chains on the folding-unfolding equilibrium of beta-peptides: a molecular dynamics simulation study. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 7276-93. PMID 16247825 DOI: 10.1002/Chem.200401129  0.527
2005 Gessier F, Schaeffer L, Kimmerlin T, Flögel O, Seebach D. Preparation of β2-amino acid derivatives (β2hThr, β2hTrp, β2hMet, β2hPro, β2hLys, pyrrolidine-3-carboxylic acid) by using DIOZ as chiral auxiliary Helvetica Chimica Acta. 88: 2235-2249. DOI: 10.1002/Hlca.200590157  0.406
2005 Seebach D, Mathad RI, Kimmerlin T, Mahajan YR, Bindschädler P, Rueping M, Jaun B, Hilty C, Etezady-Esfarjani T. NMR-solution structures in methanol of an α-heptapeptide, of a β3/β2-nonapeptide, and of an all-β3-icosapeptide carrying the 20 proteinogenic side chains Helvetica Chimica Acta. 88: 1969-1982. DOI: 10.1002/Hlca.200590151  0.579
2005 Mathad R, Gessier F, Seebach D, Jaun B. The Effect of Backbone-Heteroatom Substitution on the Folding of Peptides - A Single Fluorine Substituent Prevents a?-Heptapeptide from Folding into a314-Helix (NMR Analysis) Helvetica Chimica Acta. 88: 266-280. DOI: 10.1002/Hlca.200590008  0.375
2004 Seebach D, Beck AK, Bierbaum DJ. The world of beta- and gamma-peptides comprised of homologated proteinogenic amino acids and other components. Chemistry & Biodiversity. 1: 1111-239. PMID 17191902 DOI: 10.1002/Cbdv.200490087  0.326
2004 Wiegand H, Wirz B, Schweitzer A, Gross G, Perez MI, Andres H, Kimmerlin T, Rueping M, Seebach D. Pharmacokinetic investigation of a 14C-labelled beta 3/alpha tetrapeptide in rats. Chemistry & Biodiversity. 1: 1812-28. PMID 17191818 DOI: 10.1002/Cbdv.200490136  0.532
2004 Hook DF, Gessier F, Noti C, Kast P, Seebach D. Probing the proteolytic stability of beta-peptides containing alpha-fluoro- and alpha-hydroxy-beta-amino acids. Chembiochem : a European Journal of Chemical Biology. 5: 691-706. PMID 15122642 DOI: 10.1002/Cbic.200300827  0.313
2004 Rueping M, Mahajan YR, Jaun B, Seebach D. Design, synthesis and structural investigations of a beta-peptide forming a 314-helix stabilized by electrostatic interactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 1607-15. PMID 15054747 DOI: 10.1002/Chem.200305571  0.552
2004 Belokon YN, Harutyunyan S, Vorontsov EV, Peregudov AS, Chrustalev VN, Kochetkov KA, Pripadchev DA, Sagyan AS, Beck AK, Seebach D. Nucleophilic addition to an achiral dehydroalanine Schiff base Ni(II) complex as a route to amino acids. A case of stereodetermining asymmetric protonation in the presence of TADDOL Arkivoc. 2004: 132-150. DOI: 10.3998/Ark.5550190.0005.313  0.352
2004 Bierbaum DJ, Seebach D. Synthesis and Spectroscopic Characterization of β-Di-, β-Tri-, and β-Hexapeptides Built with (S)-2-Methylene-3-aminoalkanoic Acids Derived from Alanine, Valine, and Leucine Australian Journal of Chemistry. 57: 859. DOI: 10.1071/Ch04052  0.385
2004 Seebach D, Kimmerlin T, Šebesta R, Campo MA, Beck AK. How we drifted into peptide chemistry and where we have arrived at Tetrahedron. 60: 7455-7506. DOI: 10.1016/J.Tet.2004.06.043  0.379
2004 Lelais G, Micuch P, Josien-Lefebvre D, Rossi F, Seebach D. Preparation of Protected?2- and?3-Homocysteine,?2- and?3-Homohistidine, and?2-Homoserine for Solid-Phase Syntheses Helvetica Chimica Acta. 87: 3131-3159. DOI: 10.1002/Hlca.200490280  0.396
2004 Rueping M, Albert M, Seebach D. On the structure of PHB (=Poly[(R)-3-hydroxybutanoic acid]) in phospholipid bilayers: Preparation of trifluoromethyl-labeled oligo[(R)-3-hydroxybutanoic acid] derivatives Helvetica Chimica Acta. 87: 2473-2486. DOI: 10.1002/Hlca.200490222  0.501
2004 Lelais G, Campo M, Kopp S, Seebach D. Enantioselective Preparation ofβ2-Amino Acids with Aspartate, Glutamate, Asparagine, and Glutamine Side Chains Helvetica Chimica Acta. 87: 1545-1560. DOI: 10.1002/Hlca.200490142  0.368
2003 Peter C, Rueping M, Wörner HJ, Jaun B, Seebach D, van Gunsteren WF. Molecular dynamics simulations of small peptides: can one derive conformational preferences from ROESY spectra? Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 5838-49. PMID 14673855 DOI: 10.1002/Chem.200305147  0.524
2003 Arvidsson PI, Ryder NS, Weiss HM, Gross G, Kretz O, Woessner R, Seebach D. Antibiotic and hemolytic activity of a beta2/beta3 peptide capable of folding into a 12/10-helical secondary structure. Chembiochem : a European Journal of Chemical Biology. 4: 1345-7. PMID 14661278 DOI: 10.1002/Cbic.200300698  0.6
2003 Adam W, Alsters PL, Neumann R, Saha-Möller CR, Seebach D, Beck AK, Zhang R. Chiral hydroperoxides as oxygen source in the catalytic stereoselective epoxidation of allylic alcohols by sandwich-type polyoxometalates: control of enantioselectivity through a metal-coordinated template. The Journal of Organic Chemistry. 68: 8222-31. PMID 14535806 DOI: 10.1021/Jo034923Z  0.409
2003 Gademann K, Häne A, Rueping M, Jaun B, Seebach D. The fourth helical secondary structure of beta-peptides: the (P)-28-helix of a beta-hexapeptide consisting of (2R,3S)-3-amino-2-hydroxy acid residues. Angewandte Chemie (International Ed. in English). 42: 1534-7. PMID 12698493 DOI: 10.1002/Anie.200250290  0.692
2003 Adam W, Alsters PL, Neumann R, Saha-Möller CR, Seebach D, Zhang R. Highly efficient catalytic asymmetric epoxidation of allylic alcohols by an oxovanadium-substituted polyoxometalate with a regenerative TADDOL-derived hydroperoxide. Organic Letters. 5: 725-8. PMID 12605500 DOI: 10.1021/Ol027498P  0.346
2003 Nunn C, Rueping M, Langenegger D, Schuepbach E, Kimmerlin T, Micuch P, Hurth K, Seebach D, Hoyer D. Beta(2)/beta(3)-di- and alpha/beta(3)-tetrapeptide derivatives as potent agonists at somatostatin sst(4) receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 367: 95-103. PMID 12595949 DOI: 10.1007/S00210-002-0673-4  0.501
2003 Adam W, Beck AK, Pichota A, Saha-Möller CR, Seebach D, Vogl N, Zhang R. Control of enantioselectivity through a hydrogen-bonded template in the vanadium(V)-catalyzed epoxidation of allylic alcohols by optically active hydroperoxides Tetrahedron: Asymmetry. 14: 1355-1361. DOI: 10.1016/S0957-4166(03)00213-1  0.418
2003 Lelais G, Seebach D. Synthesis, CD Spectra, and Enzymatic Stability ofβ2-Oligoazapeptides Prepared from (S)-2-Hydrazino Carboxylic Acids Carrying the Side Chains of Val, Ala, and Leu Helvetica Chimica Acta. 86: 4152-4168. DOI: 10.1002/Hlca.200390342  0.398
2003 Sebesta R, Seebach D. Preparation of (S,S)-Fmoc-β2hIle-OH, (S)-Fmoc-β2hMet-OH, and (S)-Fmoc-β2hTyr(tBu)-OH for Solid-Phase Syntheses ofβ2- andβ2/β3-Peptides Helvetica Chimica Acta. 86: 4061-4072. DOI: 10.1002/Hlca.200390337  0.402
2003 Rossi F, Lelais G, Seebach D. Zn2+-Complexation by aβ-Peptidic Helix and Hairpin Containingβ3hCys andβ3hHis Building Blocks: Evidence from CD Measurements. Preliminary Communication Helvetica Chimica Acta. 86: 2653-2661. DOI: 10.1002/Hlca.200390215  0.343
2003 Kimmerlin T, Seebach D. Solid-Phase Synthesis of a 3-Icosapeptide Containing the Homologs of the Twenty Common Proteinaceous Amino Acids. Preliminary Communication Helvetica Chimica Acta. 86: 2098-2103. DOI: 10.1002/Hlca.200390166  0.362
2003 Gessier F, Noti C, Rueping M, Seebach D. Synthesis and CD spectra of fluoro- and hydroxy-substituted β-peptides Helvetica Chimica Acta. 86: 1862-1870. DOI: 10.1002/Hlca.200390150  0.595
2003 Seebach D, Schaeffer L, Gessier F, Bindschädler P, Jäger C, Josien D, Kopp S, Lelais G, Mahajan Y, Micuch P, Sebesta R, Schweizer B. Enantioselective Preparation of 2-Aminomethyl Carboxylic Acid Derivatives: Solving the 2-Amino Acid Problem with the Chiral Auxiliary 4-Isopropyl-5,5-diphenyloxazolidin-2-one (DIOZ). Preliminary Communication Helvetica Chimica Acta. 86: 1852-1861. DOI: 10.1002/Hlca.200390149  0.415
2003 Arvidsson P, Frackenpohl J, Seebach D. Syntheses and CD-Spectroscopic Investigations of Longer-Chain -Peptides: Preparation by Solid-Phase Couplings of Single Amino Acids, Dipeptides, and Tripeptides Helvetica Chimica Acta. 86: 1522-1553. DOI: 10.1002/Hlca.200390133  0.647
2003 Gademann K, Häne A, Rueping M, Jaun B, Seebach D. Die vierte helicale Sekundärstruktur von β-Peptiden: (P)-28-Helix eines β-Hexapeptids aus (2R,3S)-3-Amino-2-hydroxycarbonsäure-Einheiten Angewandte Chemie. 115: 1573-1575. DOI: 10.1002/Ange.200250290  0.67
2003 Rueping M, Schreiber JV, Lelais G, Jaun B, Seebach D. Mixed β2/β3-Hexapeptides and β2/β3-Nonapeptides Folding to (P)-Helices with Alternating Twelve- and Ten-Membered Hydrogen-Bonded Rings. Cheminform. 34: no-no. DOI: 10.1002/1522-2675(200209)85:9<2577::Aid-Hlca2577>3.0.Co;2-D  0.558
2003 Brenner M, Vecchia LL, Leutert T, Seebach D. (4S)‐4‐(1‐Methylethyl)‐5,5‐Diphenyl‐2‐Oxazolidinone Organic Syntheses. 80: 57-65. DOI: 10.1002/0471264180.Os080.07  0.325
2003 Beck AK, Blank S, Job K, Seebach D, Sommerfeld T. Synthesis of (S)‐2‐Methylproline: A General Method for the Preparation of α‐Branched Amino Acids Organic Syntheses. 62-62. DOI: 10.1002/0471264180.Os072.09  0.332
2003 Seebach D, Beck AK, Breitschuh R, Job K. Direct Degradation of the Biopolymer Poly[(R)‐3‐Hydroxybutyric Acid] to (R)‐3‐Hydroxybutanoic Acid and its Methyl Ester Organic Syntheses. 71: 39-47. DOI: 10.1002/0471264180.Os071.05  0.331
2003 Eberle M, Missbach M, Seebach D. Enantioselective Saponification with Pig Liver Esterase (PLE): (1S,2S,3R)‐3‐Hydroxy‐2‐nitrocyclohexyl Acetate Organic Syntheses. 19-19. DOI: 10.1002/0471264180.Os069.03  0.3
2003 Seebach D, Aebi J, Wasmuth D. Diastereoselective α‐Alkylation of β‐Hydroxycarboxylic Esters through Alkoxide Enolates: Diethyl (2S, 3R)‐( + )‐3‐Allyl‐2‐Hydroxysuccinate from Diethyl (S)‐( − )‐Malate Organic Syntheses. 109-109. DOI: 10.1002/0471264180.Os063.12  0.365
2003 Seebach D, Sutter MA, Weber RH, Züger MF. Yeast Reduction of Ethyl Acetoacetate: (S)‐( + )‐Ethyl 3‐Hydroxybutanoate Organic Syntheses. 1-1. DOI: 10.1002/0471264180.Os063.01  0.334
2003 Seebach D, Hidber A. Enantioselective Addition of Butyllithium in the Presence of the Chiral Cosolvent DDB: (R)-( + )-1-Phenyl-1-Pentanol Organic Syntheses. 42-42. DOI: 10.1002/0471264180.Os061.10  0.338
2003 Seebach D, Kalinowski H, Langer W, Crass G, Wilka E. Chiral Media for Asymmetric Solvent Inductions. (S,S)‐( + )‐1,4‐Bis(dimethylamino)‐2,3‐dimethoxybutane from (R,R)‐( + )‐Diethyl Tartrate Organic Syntheses. 24-24. DOI: 10.1002/0471264180.Os061.07  0.31
2003 Corey EJ, Seebach D. 1,3-Dithiane Organic Syntheses. 72-72. DOI: 10.1002/0471264180.Os050.22  0.517
2002 Wiegand H, Wirz B, Schweitzer A, Camenisch GP, Rodriguez Perez MI, Gross G, Woessner R, Voges R, Arvidsson PI, Frackenpohl J, Seebach D. The outstanding metabolic stability of a 14C-labeled beta-nonapeptide in rats--in vitro and in vivo pharmacokinetic studies. Biopharmaceutics & Drug Disposition. 23: 251-62. PMID 12214326 DOI: 10.1002/Bdd.334  0.577
2002 Seebach D, Mahajan YR, Senthilkumar R, Rueping M, Jaun B. Beta-depsipeptides--the effect of a missing and a weakened hydrogen bond on the stability of the beta-peptidic 3(14)-helix. Chemical Communications (Cambridge, England). 1598-9. PMID 12170800 DOI: 10.1039/B204187C  0.529
2002 Adam W, Roschmann KJ, Saha-Möller CR, Seebach D. cis-Stilbene and (1 alpha,2 beta,3 alpha)-(2-ethenyl-3-methoxycyclopropyl)benzene as mechanistic probes in the Mn(III)(salen)-catalyzed epoxidation: influence of the oxygen source and the counterion on the diastereoselectivity of the competitive concerted and radical-type oxygen transfer. Journal of the American Chemical Society. 124: 5068-73. PMID 11982371 DOI: 10.1021/Ja0177206  0.417
2002 Rueping M, Mahajan Y, Sauer M, Seebach D. Cellular uptake studies with beta-peptides. Chembiochem : a European Journal of Chemical Biology. 3: 257-9. PMID 11921409 DOI: 10.1002/1439-7633(20020301)3:2/3<257::Aid-Cbic257>3.0.Co;2-S  0.53
2002 Seebach D, Brenner M, Rueping M, Jaun B. Gamma2-, gamma3-, and gamma(2,3,4)-amino acids, coupling to gamma-hexapeptides: CD spectra, NMR solution and X-ray crystal structures of gamma-peptides. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 573-84. PMID 11855705 DOI: 10.1002/1521-3765(20020201)8:3<573::Aid-Chem573>3.0.Co;2-H  0.551
2002 Heckel A, Seebach D. Preparation and characterization of TADDOLs immobilized on hydrophobic controlled-pore-glass silica gel and their use in enantioselective heterogeneous catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 559-72. PMID 11855704 DOI: 10.1002/1521-3765(20020201)8:3<559::Aid-Chem559>3.0.Co;2-1  0.577
2002 Seebach D, Sifferlen T, Bierbaum DJ, Rueping M, Jaun B, Schweizer B, Schaefer J, Mehta AK, O'Connor RD, Meier BH, Ernst M, Glättli A. Isotopically labelled and unlabelled β-peptides with geminal dimethyl substitution in 2-position of each residue: Synthesis and NMR investigation in solution and in the solid state Helvetica Chimica Acta. 85: 2877-2917. DOI: 10.1002/1522-2675(200209)85:9<2877::Aid-Hlca2877>3.0.Co;2-W  0.588
2002 Juaristi E, Hernández-Rodríguez M, López-Ruiz H, Aviña J, Muñoz-Muñiz O, Hayakawa M, Seebach D. Synthesis of New Chiral Derivatives of N,N′-Dimethylpropyleneurea (DMPU) and Examination of Their Influence on the Regio- and Enantioselectivity of Addition of 2-(1,3-Dithianyl)lithium to Cyclohex-2-en-1-one Helvetica Chimica Acta. 85: 1999. DOI: 10.1002/1522-2675(200207)85:7<1999::Aid-Hlca1999>3.0.Co;2-K  0.359
2002 Micuch P, Seebach D. Preparation of β2-homotryptophan derivatives for β-peptide synthesis Helvetica Chimica Acta. 85: 1567-1577. DOI: 10.1002/1522-2675(200206)85:6<1567::Aid-Hlca1567>3.0.Co;2-T  0.435
2002 Gaul C, Schweizer B, Seiler P, Seebach D. Crystal Structures– AManifesto for the Superiority of the Valine-Derived 5,5-Diphenyloxazolidinone as an Auxiliary in Enantioselective Organic Synthesis Helvetica Chimica Acta. 85: 1546-1566. DOI: 10.1002/1522-2675(200206)85:6<1546::Aid-Hlca1546>3.0.Co;2-2  0.331
2002 Etezady-Esfarjani T, Hilty C, Wüthrich K, Rueping M, Schreiber J, Seebach D. NMR-structural investigations of a β3-dodecapeptide with proteinogenic side chains in methanol and in aqueous solutions Helvetica Chimica Acta. 85: 1197-1209. DOI: 10.1002/1522-2675(200205)85:5<1197::Aid-Hlca1197>3.0.Co;2-E  0.559
2002 Gaul C, Seebach D. Metallations and Reactions with Electrophiles of 4-Isopropyl-5,5-diphenyloxazolidin-2-one (DIOZ) with N-Allyl and N-Propargyl Substituents: Chiral Homoenolate Reagents Helvetica Chimica Acta. 85: 963. DOI: 10.1002/1522-2675(200204)85:4<963::Aid-Hlca963>3.0.Co;2-6  0.37
2002 Heckel A, Seebach D. Enantioselective Heterogeneous Epoxidation and Hetero-Diels-Alder Reaction with Mn- and Cr-salen Complexes Immobilized on Silica Gel by Radical Grafting Helvetica Chimica Acta. 85: 913. DOI: 10.1002/1522-2675(200203)85:3<913::Aid-Hlca913>3.0.Co;2-U  0.565
2002 Gaul C, Seebach D. Conjugate Addition of Lithiated (S)-4-Isopropyl-3- [(methylthio)methyl]-5,5-diphenyloxazolidin-2-one to Cinnamoyl Derivatives: Preparation of Enantiomerically Pure 1,4-Diols Helvetica Chimica Acta. 85: 772. DOI: 10.1002/1522-2675(200203)85:3<772::Aid-Hlca772>3.0.Co;2-I  0.381
2002 Albert M, Seebach D, Duchardt E, Schwalbe H. Synthesis and NMR Analysis in Solution of Oligo(3-hydroxyalkanoic acid) Derivatives with the Side Chains of Alanine, Valine, and Leucine (β-Depsides): Coming Full Circle from PHB toβ-Peptides to PHB Helvetica Chimica Acta. 85: 633-658. DOI: 10.1002/1522-2675(200202)85:2<633::Aid-Hlca633>3.0.Co;2-1  0.395
2002 Sellner H, Rheiner P, Seebach D. Preparation of Polystyrene Beads with Dendritically Embedded TADDOL and Use in EnantioselectiveLewis Acid Catalysis Helvetica Chimica Acta. 85: 352-387. DOI: 10.1002/1522-2675(200201)85:1<352::Aid-Hlca352>3.0.Co;2-D  0.317
2001 Arvidsson PI, Frackenpohl J, Ryder NS, Liechty B, Petersen F, Zimmermann H, Camenisch GP, Woessner R, Seebach D. On the antimicrobial and hemolytic activities of amphiphilic beta-peptides. Chembiochem : a European Journal of Chemical Biology. 2: 771-3. PMID 11948860 DOI: 10.1002/1439-7633(20011001)2:10<771::Aid-Cbic771>3.0.Co;2-#  0.595
2001 Frackenpohl J, Arvidsson PI, Schreiber JV, Seebach D. The outstanding biological stability of beta- and gamma-peptides toward proteolytic enzymes: an in vitro investigation with fifteen peptidases. Chembiochem : a European Journal of Chemical Biology. 2: 445-55. PMID 11828476 DOI: 10.1002/1439-7633(20010601)2:6<445::Aid-Cbic445>3.0.Co;2-R  0.608
2001 Gaul C, Arvidsson PI, Bauer W, Gawley RE, Seebach D. Computational, ReactIR-, and NMR-spectroscopic investigations on the chiral formyl anion equivalent N-(alpha-lithiomethylthiomethyl)-4-isopropyl-5,5-diphenyloxazolidin-2-one and related compounds. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4117-25. PMID 11686589 DOI: 10.1002/1521-3765(20011001)7:19<4117::Aid-Chem4117>3.0.Co;2-I  0.578
2001 Sellner H, Karjalainen JK, Seebach D. Preparation of dendritic and non-dendritic styryl-substituted Salens for cross-linking suspension copolymerization with styrene and multiple use of the corresponding Mn and Cr complexes in enantioselective epoxidations and hetero-Diels-Alder reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 2873-87. PMID 11486964 DOI: 10.1002/1521-3765(20010702)7:13<2873::Aid-Chem2873>3.0.Co;2-C  0.326
2001 Daura X, Gademann K, Schäfer H, Jaun B, Seebach D, van Gunsteren WF. The beta-peptide hairpin in solution: conformational study of a beta-hexapeptide in methanol by NMR spectroscopy and MD simulation. Journal of the American Chemical Society. 123: 2393-404. PMID 11456889 DOI: 10.1021/Ja003689G  0.584
2001 Gademann K, Kimmerlin T, Hoyer D, Seebach D. Peptide folding induces high and selective affinity of a linear and small beta-peptide to the human somatostatin receptor 4. Journal of Medicinal Chemistry. 44: 2460-8. PMID 11448228 DOI: 10.1021/Jm010816Q  0.61
2001 Gaul C, Schärer K, Seebach D. Lithiated 4-isopropyl-3-(methylthiomethyl)-5,5-diphenyloxazolidin-2-one: a chiral formyl anion equivalent for enantioselective preparations of 1,2-diols, 2-amino alcohols, 2-hydroxy esters, and 4-hydroxy-2-alkenoates. The Journal of Organic Chemistry. 66: 3059-73. PMID 11325271 DOI: 10.1021/Jo0155254  0.381
2001 Seebach D, Beck AK, Heckel A. TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries. Angewandte Chemie (International Ed. in English). 40: 92-138. PMID 11169693 DOI: 10.1002/1521-3773(20010105)40:1<92::Aid-Anie92>3.0.Co;2-K  0.601
2001 Seebach D, Beck AK, Heckel A. Cover Picture. Angewandte Chemie (International Ed. in English). 40: 1. PMID 11169690 DOI: 10.1002/1521-3773(20010105)40:1<1::AID-ANIE1>3.0.CO;2-F  0.516
2001 Arvidsson PI, Rueping M, Seebach D. Design, machine synthesis, and NMR-solution structure of a β-heptapeptide forming a salt-bridge stabilised 314-helix in methanol and in water Chemical Communications. 649-650. DOI: 10.1039/B101085I  0.691
2001 Seebach D, Brenner M, Rueping M, Schweizer B, Jaun B. Preparation and determination of X-ray-crystal and NMR-solution structures of γ2,3,4-peptides Chemical Communications. 207-208. DOI: 10.1039/B008377L  0.535
2001 Rueping M, Dietrich A, Buschmann V, Fritz MG, Sauer M, Seebach D. On the structure of poly(3-hydroxybutanoic acid) in solution and in phospholipid bilayers. Circular dichroism and fluorescence spectroscopy with oligo(3-hydroxybutanoic acid) derivatives Macromolecules. 34: 7042-7048. DOI: 10.1021/Ma010520U  0.502
2001 Seebach D, Brenner M, Rueping M, Schweizer B, Jaun B. ChemInform Abstract: Preparation and Determination of X-Ray-Crystal and NMR-Solution Structures of γ2,3,4-Peptides. Cheminform. 32: no-no. DOI: 10.1002/chin.200118173  0.451
2001 Seebach D, Rueping M, Arvidsson PI, Kimmerlin T, Micuch P, Noti C, Langenegger D, Hoyer D. Linear, peptidase-resistant β 2/β 3-Di- and α/β 3-tetrapeptide derivatives with nanomolar affinities to a human somatostatin receptor Helvetica Chimica Acta. 84: 3503-3510. DOI: 10.1002/1522-2675(20011114)84:11<3503::Aid-Hlca3503>3.0.Co;2-A  0.655
2001 Gademann K, Seebach D. Synthesis of cyclo-β-tripeptides and their biological in vitro evaluation as antiproliferatives against the growth of human cancer cell lines Helvetica Chimica Acta. 84: 2924-2937. DOI: 10.1002/1522-2675(20011017)84:10<2924::Aid-Hlca2924>3.0.Co;2-E  0.591
2001 Brenner M, Seebach D. Design, Synthesis, NMR-Solution and X-Ray Crystal Structure ofN-Acyl-γ-dipeptide Amides That Form aβII′-Type Turn Helvetica Chimica Acta. 84: 2155-2166. DOI: 10.1002/1522-2675(20010815)84:8<2155::Aid-Hlca2155>3.0.Co;2-8  0.418
2001 Waser P, Rueping M, Seebach D, Duchardt E, Schwalbe H. On the solution structure of PHB: Preparation and NMR analysis of isotopically labeled oligo[(R)-3-hydroxybutanoic acids] (OHBs) Helvetica Chimica Acta. 84: 1821-1845. DOI: 10.1002/1522-2675(20010613)84:6<1821::Aid-Hlca1821>3.0.Co;2-C  0.535
2001 Brenner M, Seebach D. Synthesis and CD Spectra in MeCN, MeOH, and H2O ofγ-Oligopeptides with Hydroxy Groups on the Backbone, Preliminary Communication Helvetica Chimica Acta. 84: 1181-1189. DOI: 10.1002/1522-2675(20010516)84:5<1181::Aid-Hlca1181>3.0.Co;2-0  0.39
2001 Seebach D, Schreiber J, Arvidsson P, Frackenpohl J. The Miraculous CD Spectra (and Secondary Structures?) ofβ-Peptides as They Grow Longer, Preliminary Communication Helvetica Chimica Acta. 84: 271-279. DOI: 10.1002/1522-2675(20010228)84:2<271::Aid-Hlca271>3.0.Co;2-O  0.641
2001 Le H, Hintermann T, Wessels T, Gan Z, Seebach D, Ernst R. Determination of the Amide-Plane Orientations in a Cyclo-β-Peptide by Magic-Angle-Spinning Deuterium-Correlation Spectroscopy, and Comparison with the Powder X-Ray Structure Helvetica Chimica Acta. 84: 208-221. DOI: 10.1002/1522-2675(20010131)84:1<208::Aid-Hlca208>3.0.Co;2-B  0.311
2001 Aoki M, Seebach D. Preparation of TADOOH, a Hydroperoxide from TADDOL, and Use in Highly Enantioface- and Enantiomer-Differentiating Oxidations Helvetica Chimica Acta. 84: 187-207. DOI: 10.1002/1522-2675(20010131)84:1<187::Aid-Hlca187>3.0.Co;2-O  0.351
2001 Seebach D, Beck AK, Heckel A. TADDOLe, ihre Derivate und Analoga – vielseitige chirale Hilfsstoffe Angewandte Chemie. 113: 96-142. DOI: 10.1002/1521-3757(20010105)113:1<96::Aid-Ange96>3.0.Co;2-B  0.58
2000 Gaul C, Seebach D. A valine-derived lithiated 3-methylthiomethyl-1,3-oxazolidin-2-one for enantioselective nucleophilic hydroxymethylation, formylation, and alkoxycarbonylation of aldehydes Organic Letters. 2: 1501-4. PMID 10841464 DOI: 10.1021/Ol0000410  0.373
2000 Heckel A, Seebach D. Immobilization of TADDOL with a High Degree of Loading on Porous Silica Gel and First Applications in Enantioselective Catalysis. Angewandte Chemie (International Ed. in English). 39: 163-165. PMID 10649361 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<163::Aid-Anie163>3.0.Co;2-J  0.573
2000 Rueping M, Jaun B, Seebach D. NMR structure in methanol of a β-hexapeptide with a disulfide clamp Chemical Communications. 2267-2268. DOI: 10.1039/B007503P  0.567
2000 Böhm A, Seebach D. Determination of Enantiomer Purity ofβ- andγ-Amino Acids by NMR Analysis of Diastereoisomeric Palladium Complexes Helvetica Chimica Acta. 83: 3262-3278. DOI: 10.1002/1522-2675(20001220)83:12<3262::Aid-Hlca3262>3.0.Co;2-P  0.386
2000 Cuenca A, Medio-Simón M, Aguilar G, Weibel D, Beck A, Seebach D. Highly Enantioselective Protonation of the 3,4-Dihydro-2- methylnaphthalen-1(2H)-one Li-Enolate by TADDOLs Helvetica Chimica Acta. 83: 3153-3162. DOI: 10.1002/1522-2675(20001220)83:12<3153::Aid-Hlca3153>3.0.Co;2-R  0.387
2000 Schreiber J, Seebach D. Solid-Phase Synthesis of aβ-Dodecapeptide with Seven Functionalized Side Chains and CD-Spectroscopic Evidence for a Dramatic Structural Switch When Going from Water to Methanol Solution Helvetica Chimica Acta. 83: 3139-3152. DOI: 10.1002/1522-2675(20001220)83:12<3139::Aid-Hlca3139>3.0.Co;2-W  0.356
2000 Seebach D, Sifferlen T, Mathieu P, Häne A, Krell C, Bierbaum D, Abele S. CD Spectra in Methanol ofβ-Oligopeptides Consisting ofβ-Amino Acids with Functionalized Side Chains, with Alternating Configuration, and with Geminal Backbone Substituents - Fingerprints of New Secondary Structures? Helvetica Chimica Acta. 83: 2849-2864. DOI: 10.1002/1522-2675(20001108)83:11<2849::Aid-Hlca2849>3.0.Co;2-R  0.349
2000 Seebach D, Jacobi A, Rueping M, Gademann K, Ernst M, Jaun B. Synthesis of β-hexa- and β-heptapeptides containing novel β 2,3-amino acids with two serine or two cysteine side chains - CD- and NMR-spectroscopic evidence for 3 14-helical secondary structures in water Helvetica Chimica Acta. 83: 2115-2140. DOI: 10.1002/1522-2675(20000906)83:9<2115::Aid-Hlca2115>3.0.Co;2-E  0.699
2000 Krell C, Seebach D. Preparation of Free and of Specifically Protected Oligo[β-Malic Acids] for Enzymatic Degradation Studies European Journal of Organic Chemistry. 2000: 1207-1218. DOI: 10.1002/1099-0690(200004)2000:7<1207::Aid-Ejoc1207>3.0.Co;2-2  0.358
2000 Seebach D, Schreiber J, Abele S, Daura X, van Gunsteren W. Structure and Conformation ofβ-Oligopeptide Derivatives with Simple Proteinogenic Side Chains: Circular Dichroism and Molecular Dynamics Investigations Helvetica Chimica Acta. 83: 34-57. DOI: 10.1002/(Sici)1522-2675(20000119)83:1<34::Aid-Hlca34>3.0.Co;2-B  0.314
2000 Gademann K, Ernst M, Seebach D, Hoyer D. The cyclo-β-tetrapeptide (β-HPhe-β-HThr-β-HLys-β-HTrp): Synthesis, NMR structure in methanol solution, and affinity for human somatostatin receptors Helvetica Chimica Acta. 83: 16-33. DOI: 10.1002/(Sici)1522-2675(20000119)83:1<16::Aid-Hlca16>3.0.Co;2-3  0.635
2000 Heckel A, Seebach D. Verankerung von TADDOL auf porösem Kieselgel mit hoher Beladung und erste Anwendungen in der enantioselektiven Katalyse Angewandte Chemie. 112: 165-167. DOI: 10.1002/(Sici)1521-3757(20000103)112:1<165::Aid-Ange165>3.0.Co;2-V  0.527
2000 Pichota A, Pregosin PS, Valentini M, Wörle M, Seebach D. Röntgenstrukturanalyse, Diffusionsmessungen und NOESY‐NMR‐Untersuchungen chiraler, vierkerniger CuI‐Katalysatoren aus einzähnigen Thiol‐Derivaten von TADDOL Angewandte Chemie. 112: 157-160. DOI: 10.1002/(Sici)1521-3757(20000103)112:1<157::Aid-Ange157>3.0.Co;2-R  0.334
2000 Abele S, Seebach D. Preparation of Achiral and of Enantiopure Geminally Disubstituted β-Amino Acids for β-Peptide Synthesis European Journal of Organic Chemistry. 2000: 1-15. DOI: 10.1002/(Sici)1099-0690(200001)2000:1<1::Aid-Ejoc1>3.0.Co;2-6  0.407
1999 Gademann K, Ernst M, Hoyer D, Seebach D. Synthesis and Biological Evaluation of a Cyclo-β-tetrapeptide as a Somatostatin Analogue. Angewandte Chemie (International Ed. in English). 38: 1223-1226. PMID 29711729 DOI: 10.1002/(Sici)1521-3773(19990503)38:9<1223::Aid-Anie1223>3.0.Co;2-A  0.606
1999 Seebach D, Abele S, Gademann K, Jaun B. Pleated Sheets and Turns of β-Peptides with Proteinogenic Side Chains. Angewandte Chemie (International Ed. in English). 38: 1595-1597. PMID 29710979 DOI: 10.1002/(Sici)1521-3773(19990601)38:11<1595::Aid-Anie1595>3.0.Co;2-0  0.62
1999 Seebach D, Pichota A, Beck AK, Pinkerton AB, Litz T, Karjalainen J, Gramlich V. Preparation of TADDOL Derivatives for New Applications Organic Letters. 1: 55-58. DOI: 10.1021/Ol990060D  0.34
1999 Bachmann BM, Seebach D. Investigation of the Enzymatic Cleavage of Diastereomeric Oligo(3-hydroxybutanoates) Containing Two to Eight HB Units. A Model for the Stereoselectivity of PHB Depolymerase fromAlcaligenes faecalisT1 Macromolecules. 32: 1777-1784. DOI: 10.1021/Ma981496W  0.303
1999 Gottwald K, Seebach D. Ring opening with kinetic resolution of azlactones by Ti-TADDOLates Tetrahedron. 55: 723-738. DOI: 10.1016/S0040-4020(98)01064-3  0.392
1999 Brenner M, Seebach D. Enantioselective Preparation ofγ-Amino Acids andγ-Lactams from Nitro Olefins and Carboxylic Acids, with the Valine-Derived 4-Isopropyl-5,5-diphenyl-1,3-oxazolidin-2-one as an Auxiliary Helvetica Chimica Acta. 82: 2365-2379. DOI: 10.1002/(Sici)1522-2675(19991215)82:12<2365::Aid-Hlca2365>3.0.Co;2-#  0.369
1999 Sifferlen T, Rueping M, Gademann K, Jaun B, Seebach D. β-thiopeptides: Synthesis, NMR solution structure, CD spectra and photochemistry Helvetica Chimica Acta. 82: 2067-2093. DOI: 10.1002/(Sici)1522-2675(19991215)82:12<2067::Aid-Hlca2067>3.0.Co;2-5  0.665
1999 Seebach D, Lyapkalo IM, Dahinden R. Dichloro[TADDOLato(2−)-O,O′]titanium/Dichlorobis[1-methylethoxy]titanium-Mediated, Highly Diastereo- and Enantioselective Additions of Silyl Enol Ethers to Nitro Olefins and [3+2] Cycloadditions of Primary Adducts to Acetylenes Helvetica Chimica Acta. 82: 1829-1842. DOI: 10.1002/(Sici)1522-2675(19991110)82:11<1829::Aid-Hlca1829>3.0.Co;2-#  0.39
1999 Werder M, Hauser H, Abele S, Seebach D. β‐Peptides as Inhibitors of Small‐Intestinal Cholesterol and Fat Absorption Helvetica Chimica Acta. 82: 1774-1783. DOI: 10.1002/(Sici)1522-2675(19991006)82:10<1774::Aid-Hlca1774>3.0.Co;2-O  0.311
1999 Abele S, Seiler P, Seebach D. Synthesis, Crystal Structures, and Modelling ofβ-Oligopeptides Consisting of 1-(Aminomethyl)cyclopropanecarboxylic Acid: Ribbon-Type Arrangement of Eight-Membered H-Bonded Rings Helvetica Chimica Acta. 82: 1559-1571. DOI: 10.1002/(Sici)1522-2675(19991006)82:10<1559::Aid-Hlca1559>3.0.Co;2-A  0.38
1999 Abele S, Vögtli K, Seebach D. Oligomers ofβ2- and ofβ3-Homoproline: What are the Secondary Structures ofβ-Peptides Lacking H-Bonds? Helvetica Chimica Acta. 82: 1539-1558. DOI: 10.1002/(Sici)1522-2675(19991006)82:10<1539::Aid-Hlca1539>3.0.Co;2-E  0.337
1999 Jacobi A, Seebach D. How To Stabilize or Breakβ-Peptidic Helices by Disulfide Bridges: Synthesis and CD Investigation ofβ-Peptides with Cysteine and Homocysteine Side Chains Helvetica Chimica Acta. 82: 1150-1172. DOI: 10.1002/(Sici)1522-2675(19990804)82:8<1150::Aid-Hlca1150>3.0.Co;2-O  0.358
1999 Heldmann D, Seebach D. Catalytic Enantioselective Hydrosilylation of Ketones with Rhodium-Phosphite Complexes Containing a TADDOLate and a Dihydrooxazole Unit Helvetica Chimica Acta. 82: 1096-1110. DOI: 10.1002/(Sici)1522-2675(19990707)82:7<1096::Aid-Hlca1096>3.0.Co;2-I  0.352
1999 Gademann K, Seebach D. Preparation and NMR structure of the cyclo-β-tripeptide [β3-HGlu]3 in aqueous solution: A new class of enterobactin-type C3-symmetrical ligands? Helvetica Chimica Acta. 82: 957-962. DOI: 10.1002/(Sici)1522-2675(19990609)82:6<957::Aid-Hlca957>3.0.Co;2-H  0.614
1999 Gademann K, Jaun B, Seebach D, Perozzo R, Scapozza L, Folkers G. Temperature-dependent NMR and CD spectra of β-peptides: On the thermal stability of β-peptide helices - Is the folding process of β-peptides non- cooperative? Helvetica Chimica Acta. 82: 1-11. DOI: 10.1002/(Sici)1522-2675(19990113)82:1<1::Aid-Hlca1>3.0.Co;2-N  0.62
1999 Daura X, Gademann K, Jaun B, Seebach D, van Gunsteren WF, Mark AE. Peptide Folding: When Simulation Meets Experiment Angewandte Chemie International Edition. 38: 236-240. DOI: 10.1002/(Sici)1521-3773(19990115)38:1/2<236::Aid-Anie236>3.0.Co;2-M  0.56
1999 Rheiner PB, Seebach D. Dendritic TADDOLs: Synthesis, Characterization and Use in the Catalytic Enantioselective Addition of Et2Zn to Benzaldehyde Chemistry - a European Journal. 5: 3221-3236. DOI: 10.1002/(Sici)1521-3765(19991105)5:11<3221::Aid-Chem3221>3.0.Co;2-P  0.321
1999 Seebach D, Abele S, Gademann K, Jaun B. Faltblätter und Schleifen von β-Peptiden mit proteinogenen Seitenketten Angewandte Chemie. 111: 1700-1703. DOI: 10.1002/(Sici)1521-3757(19990601)111:11<1700::Aid-Ange1700>3.0.Co;2-M  0.593
1999 Gademann K, Ernst M, Hoyer D, Seebach D. Synthese und biologische Evaluation eines Cyclo-β-tetrapeptids als Somatostatin-Analogon Angewandte Chemie. 111: 1302-1304. DOI: 10.1002/(Sici)1521-3757(19990503)111:9<1302::Aid-Ange1302>3.0.Co;2-L  0.564
1999 Daura X, Gademann K, Jaun B, Seebach D, van Gunsteren WF, Mark AE. Peptidfaltung: Wenn die Simulation das Experiment erreicht Angewandte Chemie. 111: 249-253. DOI: 10.1002/(Sici)1521-3757(19990115)111:1/2<249::Aid-Ange249>3.0.Co;2-B  0.588
1999 Götzö SP, Seebach D, Sanglier J. EPC Syntheses of Trifluorocitronellol and of Hexafluoropyrenophorin – A Comparison of Their Physiological Properties with the Nonfluorinated Analogs European Journal of Organic Chemistry. 1999: 2533-2544. DOI: 10.1002/(Sici)1099-0690(199910)1999:10<2533::Aid-Ejoc2533>3.0.Co;2-O  0.333
1999 Seebach D, Boog A, Schweizer WB. EPC-Synthesis of β-Amino Acid Derivatives through Lithiated Hydropyrimidines European Journal of Organic Chemistry. 1999: 335-360. DOI: 10.1002/(Sici)1099-0690(199901)1999:1<335::Aid-Ejoc335>3.0.Co;2-A  0.406
1998 Matthews JL, Gademann K, Jaun B, Seebach D. Linear and cyclic β3-oligopeptides with functionalised side-chains (-CH2OBn, -CO2Bn, -CH2CH2CO2Bn) derived from serine and from aspartic and glutamic acid Journal of the Chemical Society - Perkin Transactions 1. 3331-3340. DOI: 10.1039/A805478I  0.619
1998 Comina PJ, Beck AK, Seebach D. A Simple Batch Reactor for the Efficient Multiple Use of Polymer-Bound α,α,α‘,α‘-Tetraaryl-1,3-dioxolane-4,5-dimethanol Titanates in the Nucleophilic Addition of Dialkylzinc Reagents to Aldehydes Organic Process Research & Development. 2: 18-26. DOI: 10.1021/Op9700441  0.316
1998 Jaeschke G, Seebach D. Highly Enantioselective Ring Opening of Cyclic Meso-Anhydrides to Isopropyl Hemiesters with Ti−TADDOLates: An Alternative to Hydrolytic Enzymes? Journal of Organic Chemistry. 63: 1190-1197. DOI: 10.1021/Jo971731T  0.327
1998 Seebach D, Hoffmann M, Sting AR, Kinkel JN, Schulte M, Küsters E. Chromatographic resolution of synthetically useful chiral glycine derivatives by high-performance liquid chromatography Journal of Chromatography A. 796: 299-307. DOI: 10.1016/S0021-9673(97)01010-8  0.33
1998 Seebach D, Poenaru S, Folkers G, Rognan D. Synthesis of Oligo(3-hydroxybutanoate)(OHB)-Containing Peptides with High Binding Affinity to a Class-I-MHC Protein Helvetica Chimica Acta. 81: 1181-1200. DOI: 10.1002/Hlca.19980810529  0.336
1998 Greiveldinger G, Seebach D. Second-Generation Trifluoromethyl-Substituted Chiral Dendrimers Containing Triply Branched Building Blocks: CF3 as sensitive NMR probe for ?remote? diastereotopicity Helvetica Chimica Acta. 81: 1003-1022. DOI: 10.1002/Hlca.19980810515  0.365
1998 Hintermann T, Gademann K, Jaun B, Seebach D. γ‐Peptides Forming More Stable Secondary Structures than α‐Peptides: Synthesis and helical NMR‐solution structure of the γ‐hexapeptide analog of H‐(Val‐Ala‐Leu)2‐OH Helvetica Chimica Acta. 81: 983-1002. DOI: 10.1002/Hlca.19980810514  0.609
1998 Seebach D, Abele S, Gademann K, Guichard G, Hintermann T, Jaun B, Matthews JL, Schreiber JV, Oberer L, Hommel U, Widmer H. ?2- and ?3-Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the influence of solvation and hydrophobic interactions on folding Helvetica Chimica Acta. 81: 932-982. DOI: 10.1002/Hlca.19980810513  0.64
1998 Murer P, Seebach D. Synthesis and Properties of Monodisperse Chiral Dendrimers (up to Fourth Generation) with doubly branched building blocks: An intriguing solvent effect Helvetica Chimica Acta. 81: 603-631. DOI: 10.1002/Hlca.19980810313  0.326
1998 Guichard G, Abele S, Seebach D. Preparation ofN-Fmoc-Protected ?2- and ?3-Amino Acids and their use as building blocks for the solid-phase synthesis of ?-peptides Helvetica Chimica Acta. 81: 187-206. DOI: 10.1002/Hlca.19980810202  0.395
1998 Bachmann B, Seebach D. Synthesis and Structure of Linear and Cyclic Oligomers of 3-Hydroxybutanoic Acid with Specific Sequences of (R)- and (S)-Configurations Helvetica Chimica Acta. 81: 2430-2461. DOI: 10.1002/(Sici)1522-2675(19981216)81:12<2430::Aid-Hlca2430>3.0.Co;2-W  0.384
1998 Fritz M, Seebach D. Synthesis of Amino-Acid-, Carbohydrate-, Coumarin-, and Biotin-Labelled Oligo[(R)-3-Hydroxybutanoic Acids] (OHB) Helvetica Chimica Acta. 81: 2414-2429. DOI: 10.1002/(Sici)1522-2675(19981216)81:12<2414::Aid-Hlca2414>3.0.Co;2-C  0.352
1998 Seebach D, Abele S, Sifferlen T, Hänggi M, Gruner S, Seiler P. Preparation and Structure ofβ-Peptides Consisting of Geminally Disubstitutedβ2,2- andβ3,3-Amino Acids: A Turn Motif forβ-Peptides Helvetica Chimica Acta. 81: 2218-2243. DOI: 10.1002/(Sici)1522-2675(19981216)81:12<2218::Aid-Hlca2218>3.0.Co;2-0  0.405
1998 Abele S, Guichard G, Seebach D. (S)-β3-Homolysine- and (S)-β3-Homoserine-Containingβ-Peptides: CD Spectra in Aqueous Solution Helvetica Chimica Acta. 81: 2141-2156. DOI: 10.1002/(Sici)1522-2675(19981216)81:12<2141::Aid-Hlca2141>3.0.Co;2-5  0.347
1998 Hintermann T, Seebach D. A Useful Modification of theEvans Auxiliary: 4-Isopropyl-5,5-diphenyloxazolidin-2-one Helvetica Chimica Acta. 81: 2093-2126. DOI: 10.1002/(Sici)1522-2675(19981111)81:11<2093::Aid-Hlca2093>3.0.Co;2-X  0.329
1998 Matt T, Seebach D. C‐Alkylation of Peptides Containing Aminomalonate and (Amino)(cyano)acetate Residues Helvetica Chimica Acta. 81: 1845-1895. DOI: 10.1002/(Sici)1522-2675(19981007)81:10<1845::Aid-Hlca1845>3.0.Co;2-L  0.399
1998 Hoffmann M, Blank S, Seebach D, K�sters E, Schmid E. Separation of (R)- and (S)-tert-butyl 2-tert-butyl-4-methoxy-2,5-dihydro-1,3-imidazole-1-carboxylate (building block for amino acid synthesis) by preparative high performance liquid chromatography on a polysaccharide stationary phase Chirality. 10: 217-222. DOI: 10.1002/(Sici)1520-636X(1998)10:3<217::Aid-Chir3>3.0.Co;2-6  0.314
1998 Seebach D, Hoffmann M. Preparation and Use in Amino Acid Synthesis of a New Chiral Glycine Derivative – (R)- and (S)-tert-Butyl 2-tert-Butyl-4-methoxy-2,5-dihydroimidazole-1-carboxylate (BDI)⋆ European Journal of Organic Chemistry. 1998: 1337-1351. DOI: 10.1002/(Sici)1099-0690(199807)1998:7<1337::Aid-Ejoc1337>3.0.Co;2-T  0.425
1997 Hintermann T, Seebach D. Synthesis of a β-Hexapeptide from (R)-2-Aminomethyl-alkanoic Acids and Structural Investigations Synlett. 1997: 437-438. DOI: 10.1055/S-1997-6117  0.36
1997 Seebach D, Matthews JL. β-Peptides: a surprise at every turn Chemical Communications. 2015-2022. DOI: 10.1039/A704933A  0.364
1997 Seebach D, Jaeschke G, Gottwald K, Matsuda K, Formisano R, Chaplin DA, Breuning M, Bringmann G. Resolution of racemic carboxylic acid derivatives by Ti-TADDOLate mediated esterification reactions—A general method for the preparation of enantiopure compounds Tetrahedron. 53: 7539-7556. DOI: 10.1016/S0040-4020(97)00456-0  0.384
1997 Matthews JL, Overhand M, Kühnle FNM, Ciceri PE, Seebach D. β-peptides: Oligo-β-homoalanines - The amide analogues of poly(3-hydroxybutanoate) Liebigs Annales. 1371-1379. DOI: 10.1002/Jlac.199719970714  0.652
1997 Seebach D, Jaeschke G, Pichota A, Audergon L. Enantioselective 1,4-Addition of AliphaticGrignard Reagents to Enones Catalyzed by Readily Available Copper(I) thiolates derived from TADDOL. Preliminary communication Helvetica Chimica Acta. 80: 2515-2519. DOI: 10.1002/Hlca.19970800819  0.351
1997 Seebach D, Gademann K, Schreiber JV, Matthews JL, Hintermann T, Jaun B, Oberer L, Hommel U, Widmer H. ‘Mixed’ β-peptides: A unique helical secondary structure in solution. Preliminary communication Helvetica Chimica Acta. 80: 2033-2038. DOI: 10.1002/Hlca.19970800703  0.606
1997 Murer PK, Lapierre J, Greiveldinger G, Seebach D. Synthesis and Properties of First and Second Generation Chiral Dendrimers with Triply Branched Units: A Spectacular Case of Diastereoselectivity Helvetica Chimica Acta. 80: 1648-1681. DOI: 10.1002/Hlca.19970800522  0.321
1997 Seebach D, Herrmann GF, Lengweiler UD, Amrein W. Synthesis of Monodisperse Macromolecular Bicyclic and dendritic compounds from (R)‐3‐hydroxybutanoic acid and benzene‐1,3,5‐tricarboxylic acid and analysis by fragmenting MALDI‐TOF mass spectroscopy Helvetica Chimica Acta. 80: 989-1026. DOI: 10.1002/Hlca.19970800402  0.363
1997 Seebach D, Matthews JL, Meden A, Wessels T, Baerlocher C, McCusker LB. Cyclo-β-peptides: Structure and tubular stacking of cyclic tetramers of 3-aminobutanoic acid as determined from powder diffraction data Helvetica Chimica Acta. 80: 173-182. DOI: 10.1002/Hlca.19970800116  0.348
1997 Guibourdenche C, Seebach D, Natt F. Use of the Wolff Rearrangement of Diazo Ketones from Amino Acids as a synthetic method for the formation of oligonucleo‐peptides: A novel approach to chimeric biomolecules Helvetica Chimica Acta. 80: 1-13. DOI: 10.1002/Hlca.19970800102  0.373
1996 Sting AR, Seebach D. Synthesis of (2R, 3S)- or (2S, 3R)-2-amino-3-trifluoromethyl-3-hydroxyalkanoic acid derivatives (threonine and allo-threonine analogs) from enantiopure 4,4,4-trifluoro-3-hydroxybutanoic acid Tetrahedron. 52: 279-290. DOI: 10.1016/0040-4020(95)00895-F  0.382
1996 Seebach D, Ciceri PE, Overhand M, Jaun B, Rigo D, Oberer L, Hommel U, Amstutz R, Widmer H. Probing the Helical Secondary Structure of Short-Chain ?-Peptides Helvetica Chimica Acta. 79: 2043-2066. DOI: 10.1002/Hlca.19960790802  0.646
1996 Seebach D, Marti RE, Hintermann T. Polymer- and Dendrimer-Bound Ti-TADDOLates in Catalytic (and Stoichiometric) Enantioselective Reactions: Are pentacoordinate cationic Ti complexes the catalytically active species? Helvetica Chimica Acta. 79: 1710-1740. DOI: 10.1002/Hlca.19960790621  0.353
1996 Seebach D, Overhand M, Kühnle FNM, Martinoni B, Oberer L, Hommel U, Widmer H. 80. β-peptides: Synthesis by Arndt-Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X-Ray crystallography. Helical secondary structure of a β-hexapeptide in solution and its stability towards pepsin Helvetica Chimica Acta. 79: 913-941. DOI: 10.1002/Hlca.19960790402  0.659
1996 Ramón DJ, Guillena G, Seebach D. Nonreductive Enantioselective Ring Opening ofN-(Methylsulfonyl)dicarboximides with Diisopropoxytitanium α,α,α′,α′-Tetraaryl-1,3-dioxolane-4,5-dimethanolate Helvetica Chimica Acta. 79: 875-894. DOI: 10.1002/Hlca.19960790328  0.369
1996 Lengweiler UD, Fritz MG, Seebach D. Synthese monodisperser linearer und cyclischer Oligomere der (R)‐3‐Hydroxybuttersäure mit bis zu 128 Einheiten Helvetica Chimica Acta. 79: 670-701. DOI: 10.1002/Hlca.19960790311  0.362
1996 Seebach D, Bezençon O, Jaun B, Pietzonka T, Matthews JL, Kühnle FNM, Schweizer WB. FurtherC-Alkylations of CyclotetrapeptidesviaLithium and Phosphazenium (P4) Enolates: Discovery of a New Conformation Helvetica Chimica Acta. 79: 588-608. DOI: 10.1002/Hlca.19960790303  0.396
1996 Brunner A, Kühnle FNM, Seebach D. Preparation, Structure, and Reactivity of Thioxo and Imino Derivatives of the Triolide (and Pentolide) from (R)-3-Hydroxybutanoic Acid Helvetica Chimica Acta. 79: 319-345. DOI: 10.1002/Hlca.19960790202  0.415
1996 Seebach D, Herrmann GF, Lengweiler UD, Bachmann BM, Amrein W. Synthesis and Enzymatic Degradation of Dendrimers from (R)‐3‐Hydroxybutanoic Acid and Trimesic Acid Angewandte Chemie. 35: 2795-2797. DOI: 10.1002/Anie.199627951  0.323
1996 Seebach D, Sting AR, Hoffmann M. Self-Regeneration of Stereocenters (SRS)—Applications, Limitations, and Abandonment of a Synthetic Principle†‡ Angewandte Chemie. 35: 2708-2748. DOI: 10.1002/Anie.199627081  0.421
1996 Seebach D, Sting AR, Hoffmann M. Die Selbstregeneration von Stereozentren (SRS) — Anwendungen, Grenzen und Preisgabe eines Syntheseprinzips Angewandte Chemie. 108: 2881-2921. DOI: 10.1002/Ange.19961082304  0.36
1995 Brandl H, Aeberli B, Bachofen R, Schwegler I, Muller HM, Burger MH, Hoffmann T, Lengweiler UD, Seebach D. Biodegradation of cyclic and substituted linear oligomers of poly(3-hydroxybutyrate). Canadian Journal of Microbiology. 41: 180-6. PMID 7606662 DOI: 10.1139/M95-185  0.33
1995 Juaristi E, Anzorena JL, Boog A, Madrigal D, Seebach D, Garcia-Baez EV, Garcia-Barradas O, Gordillo B, Kramer A. Highly Diastereoselective Alkylation of 1-Benzoyl-2-alkyl-3-(1'-methylbenzyl)imidazolidin-4-ones Journal of Organic Chemistry. 60: 6408-6415. DOI: 10.1021/Jo00125A029  0.341
1995 Seebach D, Dahinden R, Marti RE, Beck AK, Plattner DA, Kuehnle FNM. On the Ti-TADDOLate-Catalyzed Diels-Alder Addition of 3-Butenoyl-1,3-oxazolidin-2-one to Cyclopentadiene. General Features of Ti-BINOLate- and Ti-TADDOLate-Mediated Reactions Journal of Organic Chemistry. 60: 1788-1799. DOI: 10.1021/Jo00111A042  0.373
1995 Schäfer H, Seebach D. Enantioselective conjugate addition of primary dialkylzinc reagents to 2-aryl- and 2-heteroaryl-nitroolefins mediated by titanium-TADDOLates preparation of enantioenriched 2-aryl-alkylamines Tetrahedron. 51: 2305-2324. DOI: 10.1016/0040-4020(94)01100-E  0.36
1995 Stamm T, Kouwenhoven H, Seebach D, Prins R. Zeolite-Catalyzed Isomerization of Aromatic Amines to Methyl-Aza-Aromatics Journal of Catalysis. 155: 268-282. DOI: 10.1006/Jcat.1995.1209  0.349
1995 Podlech J, Seebach D. On the preparation of β‐amino acids from α‐amino acids using the Arndt‐Eistert reaction: Scope, limitations and stereoselectivity. Application to carbohydrate peptidation. Stereoselective α‐alkylations of some β‐amino acids Liebigs Annalen. 1995: 1217-1228. DOI: 10.1002/Jlac.1995199507163  0.415
1995 Marti RE, Heinzer J, Seebach D. Preparation and reactions of silyl nitronates derived from 2,2,2-trifluoronitroethane. Diastereoselective synthesis of trifluoromethyl-substituted aminoethanols and -propanols Liebigs Annalen. 1995: 1193-1215. DOI: 10.1002/Jlac.1995199507162  0.387
1995 Studer A, Seebach D. Enantioselective synthesis of α-branched α-amino acids with bulky substituents Liebigs Annalen. 1995: 217-222. DOI: 10.1002/Jlac.199519950231  0.547
1995 Seebach D, Devaquet E, Ernst A, Hayakawa M, Kühnle FNM, Bernd Schweizer W, Weber B. Preparation of the PdCl2Complex of TADDOP, the Bis(diphenylphosphinite) of TADDOL: Use in enantioselective 1,3-diphenylallylations of nucleophiles and discussion of the mechanism Helvetica Chimica Acta. 78: 1636-1650. DOI: 10.1002/Hlca.19950780703  0.334
1995 Seebach D, Hoffmann T, Kühnle FNM, Kinkel JN, Schulte M. Preparation, Structure, and Properties of All Possible Cyclic Dimers (Diolides) of 3-Hydroxybutanoic Acid Helvetica Chimica Acta. 78: 1525-1540. DOI: 10.1002/Hlca.19950780611  0.384
1995 Podlech J, Seebach D. Azetidin-3-ones from (S)-?-Amino Acids and Their Reactions with Nucleophiles: Preparation of some azetidine-containing amino-alcohol and amino-acid derivatives Helvetica Chimica Acta. 78: 1238-1246. DOI: 10.1002/Hlca.19950780516  0.353
1995 Studer A, Hintermann T, Seebach D. Synthesis and First Applications of a New Chiral Auxiliary (tert-butyl 2-(tert-butyl)-5,5-dimethyl-4-oxoimidazolidine-1-carboxylate) Helvetica Chimica Acta. 78: 1185-1206. DOI: 10.1002/Hlca.19950780512  0.538
1995 Seebach D, Jaeschke G, Wang YM. Highly Enantioselective Opening of Cyclicmeso-Anhydrides to Isopropyl Hemiesters with Diisopropoxytitanium TADDOLates Angewandte Chemie International Edition in English. 34: 2395-2396. DOI: 10.1002/Anie.199523951  0.323
1995 Sommerfeld T, Seebach D. Synthesis of ψ[SCH2]‐, ψ[SOCH2]‐, and ψ[SO2CH2]‐Peptide Isosters Angewandte Chemie. 34: 553-554. DOI: 10.1002/Anie.199505531  0.303
1995 Murer P, Seebach D. Synthese Und Eigenschaften Von Dendrimeren Erster Bis Dritter Generation Mit Zwei- Und Dreifach Verzweigenden Chiralen Bausteinen Angewandte Chemie. 107: 2297-2300. DOI: 10.1002/Ange.19951071913  0.304
1994 Seebach D, Murer P, Rheiner B, Juaristi E. Enantioselective Synthesis ob b-Amino Acids. 5. Stereoselective Reaction of Chiral Pyrimidinone Enolates with Aldehydes Heterocycles. 39: 319-344. DOI: 10.3987/Com-94-S(B)35  0.35
1994 Weber B, Seebach D. Ti-TADDOLate-catalyzed, highly enantioselective addition of alkyl- and aryl-titanum derivatives to aldehydes Tetrahedron. 50: 7473-7484. DOI: 10.1016/S0040-4020(01)90475-2  0.379
1994 Weber B, Seebach D. Highly enantioselective addition of primary alkyl Grignard reagents to carbocyclic and heterocyclic arylketones in the presence of magnesium TADDOLate preparative and mechanistic aspects Tetrahedron. 50: 6117-6128. DOI: 10.1016/S0040-4020(01)90463-6  0.378
1994 Seebach D, Beck AK, Schmidt B, Wang YM. Enantio- and diastereoselective titanium-TADDOLate catalyzed addition of diethyl and bis(3-buten-1-yl) zinc to aldehydes a full account with preparative details Tetrahedron. 50: 4363-4384. DOI: 10.1016/S0040-4020(01)89373-X  0.408
1994 Maestro MA, Sefkow M, Seebach D. Total Synthesis of Myxovirescins, 3 Coupling of the Two Key Fragments and Last Steps to Myxovirescins A1 and M2 Liebigs Annalen Der Chemie. 1994: 731-738. DOI: 10.1002/Jlac.199419940714  0.313
1994 Sefkow M, Neidlein A, Sommerfeld T, Sternfeld F, Maestro MA, Seebach D. Total Synthesis of Myxovirescins, 2 Assembly of the “Northwestern” Part [C(15)–C(28)] Liebigs Annalen Der Chemie. 1994: 719-729. DOI: 10.1002/Jlac.199419940713  0.319
1994 Seebach D, Maestro MA, Sefkow M, Adam G, Hintermann S, Neidlein A. Total Synthesis of Myxovirescins, 1 Strategy and Construction of the “Southeastern” Part [O(1)–C(14)] Liebigs Annalen Der Chemie. 1994: 701-717. DOI: 10.1002/Jlac.199419940712  0.343
1994 Ito YN, Ariza X, Beck AK, Boháč A, Ganter C, Gawley RE, Kühnle FNM, Tuleja J, Wang YM, Seebach D. Preparation and Structural Analysis of Several New α,α,α′,α′-Tetraaryl-1,3-dioxolane-4,5-dimethanols (TADDOL's) and TADDOL analogs, their evaluation as titanium ligands in the enantioselective addition of methyltitanium and diethylzinc reagents to benzald Helvetica Chimica Acta. 77: 2071-2110. DOI: 10.1002/Hlca.19940770802  0.343
1994 Seebach D, Studer A, Pfammatter E, Widmer H. Synthesis of Tri-, Penta-, and Heptapeptides Containing and (R)-2-alkyl-2-amino-3-(methylamino)-propionic acid residue in the central position Helvetica Chimica Acta. 77: 2035-2050. DOI: 10.1002/Hlca.19940770728  0.547
1994 Seebach D, Hoffmann T, Kühnle FNM, Lengweiler UD. Preparation and Structure of Oligolides from (R)-3-Hydroxypentanoic Acid and comparison with the hydroxybutanoic-acid derivatives: A small change with large consequences Helvetica Chimica Acta. 77: 2007-2034. DOI: 10.1002/Hlca.19940770727  0.327
1994 Seebach D, Lapierre J, Greiveldinger G, Skobridis K. Synthesis of Chiral Starburst Dendrimers from PHB-Derived Triols as Central Cores Helvetica Chimica Acta. 77: 1673-1688. DOI: 10.1002/Hlca.19940770702  0.35
1994 Seebach D, Sommerfeld TL, Jiang Q, Venanzi LM. Preparation of Oxazolidine-Containing Peptides: Unusual effects in RhIII-catalyzed acetalizations of aldehydes with urethane-protected serine and threonine esters and with dipeptides containing serine or threonine residues at the N-terminus Helvetica Chimica Acta. 77: 1313-1330. DOI: 10.1002/Hlca.19940770513  0.425
1994 Bossler HG, Seebach D. Peptide Enolates.C-Alkylation of Glycine Residues in linear tri-, tetra-, and pentapeptidesvia dilithium azadienediolates Helvetica Chimica Acta. 77: 1124-1165. DOI: 10.1002/Hlca.19940770424  0.346
1994 Gautschi M, Schweizer WB, Seebach D. In 2‐ und 3‐Stellung verzweigte, enantiomerenreine 4,4,4‐Trifluor‐3‐hydroxy‐buttersäure‐Derivate aus 6‐Trifluormethyl‐1,3‐dioxan‐und ‐dioxin‐4‐onen Chemische Berichte. 127: 565-579. DOI: 10.1002/Cber.19941270317  0.394
1994 Seebach D, Lapierre J, Skobridis K, Greiveldinger G. Chiral Dendrimers from Tris(hydroxymethyl)methane Derivatives Angewandte Chemie. 33: 440-442. DOI: 10.1002/Anie.199404401  0.33
1993 Juaristi E, Beck AK, Hansen J, Matt T, Mukhopadhyay T, Simson M, Seebach D. Enantioselective Aldol and Michael Additions of Achiral Enolates in the Presence of Chiral Lithium Amides and Amines Synthesis. 1993: 1271-1290. DOI: 10.1055/S-1993-26041  0.367
1993 Seebach D, Hayakawa M, Sakaki J, Schweizer W. Derivatives of α,α,α′,α′-Tetraaryl-2,2-dimethyl-1,3-dioxolan-4,5-dimethanol (TADDOL) containing nitrogen, sulfur, and phosphorus atoms. New ligands and auxiliaries for enantioselective reactions. Tetrahedron. 49: 1711-1724. DOI: 10.1016/S0040-4020(01)80529-9  0.397
1993 Blank S, Seebach D. Herstellung von (R,R)‐ oder (S,S)‐2‐Amino‐3‐hydroxycarbonsäuren (allo‐Threonin‐Analoge) durch Acylierung/Reduktion von 2‐t‐Butyl‐3‐methyl‐4‐oxoimidazolidin‐1‐carbonsäure‐t‐butylester (Boc‐BMI) European Journal of Organic Chemistry. 1993: 889-896. DOI: 10.1002/Jlac.1993199301140  0.417
1993 Seebach D, Gees T, Schuler F. Herstellung von α‐verzweigten Phenylalaninen und von 1,1‐disubstituierten Ethylendiaminen über chirale Imidazolidinone und Oxazolidinone aus Glycin – präparative und mechanistische Aspekte European Journal of Organic Chemistry. 1993: 785-799. DOI: 10.1002/Jlac.1993199301124  0.406
1993 Sakaki J, Schweizer WB, Seebach D. Catalytic Enantioselective Hydrosilylation of Aromatic Ketones Using Rhodium Complexes of TADDOL-Derived Cyclic Phosphonites and Phosphites Helvetica Chimica Acta. 76: 2654-2665. DOI: 10.1002/Hlca.19930760722  0.407
1993 Gees T, Schweizer WB, Seebach D. An Unusual Rearrangement of a Lithiated N-Acyl-tetrahydroisoquinoline to an Amino-indan Skeleton and Structural Comparison of 3-Amino-2-methylindan- and -tetrahydronaphthalene-2-carboxylic Acids as Possible Building Blocks for Peptide-Turn Mimics Helvetica Chimica Acta. 76: 2640-2653. DOI: 10.1002/Hlca.19930760721  0.436
1993 Seebach D, Bürger HM, Plattner DA, Nesper R, Fässler T. Complexes of the Triolide from (R)-3-Hydroxybutanoic Acid with Sodium, Potassium, and Barium Salts: Crystal Structures, Ester Chelates and Ester Crowns, Crystal Packing, Bonding, and Electron-Localization Functions Helvetica Chimica Acta. 76: 2581-2601. DOI: 10.1002/Hlca.19930760718  0.301
1993 Lapierre J, Skobridis K, Seebach D. Preparation of Chiral Building Blocks for Starburst Dendrimer Synthesis Helvetica Chimica Acta. 76: 2419-2432. DOI: 10.1002/Hlca.19930760702  0.363
1993 Plattner DA, Brunner A, Dobler M, Müller H, Petter W, Zbinden P, Seebach D. Cyclische Oligomere von (R)-3-Hydroxybuttersäure: Herstellung und strukturelle Aspekte† Helvetica Chimica Acta. 76: 2004-2033. DOI: 10.1002/Hlca.19930760518  0.39
1993 Sommerfeld TL, Seebach D. Dehydroalanine-Containing Peptides by AcOH-Elimination fromO-Acetylserine Residuces with DBU/LiClO4 in Tetrahydrofuran Helvetica Chimica Acta. 76: 1702-1714. DOI: 10.1002/Hlca.19930760427  0.322
1993 Seebach D, Beck AK, Bossler HG, Gerber C, Ko SY, Murtiashaw CW, Naef R, Shoda S, Thaler A, Krieger M, Wenger R. Modification of Cyclosporin A (CS): Generation of an enolate at the sarcosine residue and reactions with electrophiles Helvetica Chimica Acta. 76: 1564-1590. DOI: 10.1002/Hlca.19930760415  0.362
1993 Miller SA, Griffiths SL, Seebach D. C-Alkylation of Sarcosine Residues in Cyclic Tetrapeptidesvia Lithium Enlates Helvetica Chimica Acta. 76: 563-595. DOI: 10.1002/Hlca.19930760138  0.408
1993 Seebach D, Lapierre J, Jaworek W, Seiler P. A Simple Procedure for the Preparation of Chiral ?Tris(hydroxymethyl)methane? Derivatives Helvetica Chimica Acta. 76: 459-475. DOI: 10.1002/Hlca.19930760130  0.391
1993 Lapierre J, Gautschi M, Greiveldinger G, Seebach D. Reaction of 6‐(CF3)‐ and 6‐(CH3)‐2‐(tert‐Butyl)‐1,3‐dioxan‐4‐one Li Enolate with Two Equivalents of an Aldehyde – Unusual Reorganizations of Aldolates Chemische Berichte. 126: 2739-2746. DOI: 10.1002/Cber.19931261225  0.303
1993 Blank S, Seebach D. (R)- and(S)-4-Alkoxy-2-tert-butyl-2,5-dihydroimidazole-1-carboxylates—New Chiral Glycine Derivatives for Amino Acid Synthesis Angewandte Chemie International Edition in English. 32: 1765-1766. DOI: 10.1002/Anie.199317651  0.375
1992 Breitschuh R, Seebach D. Herstellung von steroisomeren 3-Sulfinylbuttersäuren aus (R)- und (S)-4-Methyl-2-oxetanon Synthesis. 1992: 83-89. DOI: 10.1055/S-1992-34181  0.313
1992 Seebach D, Gysel U, Job K, Beck AK. Modified Preparation of (2R)-2-tert-Butyl-6-methyl-4H-1,3-dioxin-4-one; a Chiral Acetylacetic Acid Derivative for the Synthesis of Enantiopure Compounds Synthesis. 1992: 39-40. DOI: 10.1055/S-1992-34162  0.34
1992 Breitschuh R, Seebach D. Herstellung enantiomerenreiner Sulfoxide aus Milchsäure und 3-Hydroxybuttersäure: Isopropenyl-tolyl-sulfoxid und 2-(Phenylsulfinyl) acrylester Synthesis. 1992: 1170-1178. DOI: 10.1055/S-1992-26328  0.35
1992 Juaristi E, Escalante J, Lamatsch B, Seebach D. Enantioselective synthesis of .beta.-amino acids. 2. Preparation of the like stereoisomers of 2-methyl- and 2-benzyl-3-aminobutanoic acid Journal of Organic Chemistry. 57: 2396-2398. DOI: 10.1021/Jo00034A037  0.381
1992 von dem Bussche-Hünnefeld JL, Seebach D. Enantioselective preparation of sec. Alcohols from aldehydes and dialkyl zinc compounds, generated in situ from Grignard reagents, using substoichiometric amounts of TADDOL-titanates Tetrahedron. 48: 5719-5730. DOI: 10.1016/0040-4020(92)80023-9  0.394
1992 Seebach D, Pfammatter E, Gramlich V, Bremi T, Kühnle F, Portmann S, Tironi I. Diastereoselective Michael Additions of Chiral Imidazolidines to Trityl Enones Liebigs Annalen Der Chemie. 1992: 1145-1151. DOI: 10.1002/Jlac.1992199201188  0.31
1992 Suzuki K, Seebach D. threo-3-Alkyl- and -Arylglutamic Acid Derivatives by Michael Additions of Boc-BMI Li-Enolates to 2,6-Di-t-butyl-4-methoxyphenyl Alkenoates on the Diastereoselectivity of the Coupling of Trigonal Centers Involving Heterocyclic Li-Enolates Liebigs Annalen Der Chemie. 1992: 51-61. DOI: 10.1002/Jlac.199219920111  0.518
1992 Seebach D, Plattner DA, Beck AK, Wang YM, Hunziker D, Petter W. On the Mechanisms of Enantioselective Reactions Using α,α,α′,α′ -Tetraaryl-1,3-dioxolane-4,5-dimethanol(TADDOL)-Derived Titanates: Differences between C2- and C1-symmetrical TADDOLs – facts, implications and generalizations† Helvetica Chimica Acta. 75: 2171-2209. DOI: 10.1002/Hlca.19920750704  0.398
1992 Seebach D, Amatsch B, Amstutz R, Beck AK, Doler M, Egli M, Fitzi R, Gautschi M, Herradön B, Hidber PC, Irwin JJ, Locher R, Maestro M, Maetzke T, Mouriño A, et al. Structure and Reactivity of Five‐ and Six‐Ring N, N‐, N, O‐, and O, O‐acetals: A lesson in allylic 1, 3‐strain (A1, 3 strain) Helvetica Chimica Acta. 75: 913-934. DOI: 10.1002/Hlca.19920750326  0.321
1992 Müller W, Lowe DA, Neijt H, Urwyler S, Herrling PL, Blaser D, Seebach D. Synthesis andN-Methyl-D-aspartate (NMDA) Antagonist Properties of the Enantiomers of α-Amino-5-(phosphonomethyl)[1,1′-biphenyl]-3-propanoic Acid. Use of a New Chiral Glycine Derivative Helvetica Chimica Acta. 75: 855-864. DOI: 10.1002/Hlca.19920750320  0.337
1992 Von Dem Bussche-Hünnefeld C, Beck AK, Lengweiler U, Seebach D. α,α,α′,α′-Tetraaryl-1,3-dioxolane-4,5-dimethanols (TADDOLs) for Resolutions of Alcohols and as Chiral Solvating Agents in NMR Spectroscopy Helvetica Chimica Acta. 75: 438-441. DOI: 10.1002/Hlca.19920750203  0.338
1992 Bussche–Hünnefeld CVD, Cescato C, Seebach D. Ergiebige Herstellung von (R)- und (S)-3,3,3-Trifluormilchsäure und von (R)- und (S)-(Trifluormethyl)oxiran Chemische Berichte. 125: 2795-2802. DOI: 10.1002/Cber.19921251227  0.331
1992 Bussche‐Hünnefeld CVD, Seebach D. Herstellung und Umsetzungen von (R,R)‐ und (S,S)‐3‐Trifluormethyloxiran‐2‐carbonsäure‐ethylester, einem vielseitigen, leicht zugänglichen CF3‐haltigen Synthesebaustein Chemische Berichte. 125: 1273-1281. DOI: 10.1002/Cber.19921250538  0.363
1992 Gautschi M, Seebach D. Synthesis of (R)- and (S)2-tert-Butyl-6-trifluoro-methyl-1,3-dioxin-4-ones, Transformations into 3-Hydroxy-3-(trifluoromethyl)alkanoates, and Surprising Differences in the Reactivity of CH3- and CF3-Substituted Compounds† Angewandte Chemie. 31: 1083-1085. DOI: 10.1002/Anie.199210831  0.32
1992 Weber B, Seebach D. Enantiomerenreine tertiäre Alkohole durch TADDOL-vermittelte Additionen an Ketone - oder wie man ein Grignard-Reagens enantioselektiv macht† Angewandte Chemie. 104: 96-97. DOI: 10.1002/Ange.19921040133  0.339
1991 Blaser D, Ko SY, Seebach D. A stereoselective synthesis of MeBmt employing a new chiral glycine enolate derivative Journal of Organic Chemistry. 56: 6230-6233. DOI: 10.1021/Jo00021A050  0.326
1991 Juaristi E, Quintana D, Lamatsch B, Seebach D. Asymmetric synthesis of .beta.-amino acids. 1. Highly diastereoselective addition of a racemic .beta.-alanine enolate derivative to electrophiles Journal of Organic Chemistry. 56: 2553-2557. DOI: 10.1021/Jo00007A053  0.445
1991 Seebach D, Maetzke T, Petter W, Kloetzer B, Plattner DA. Pyramidalization and reactivity of trigonal centers. X-ray crystal structure analysis of two silyl enol ethers from 1-benzoyl- and 1-(methoxycarbonyl)-2-tert-butyl-3,5-dimethyl-4-imidazolidinone (reagents for amino acid synthesis) Journal of the American Chemical Society. 113: 1781-1786. DOI: 10.1021/Ja00005A049  0.324
1991 Pfammatter E, Seebach D. Preparation of (R)- and (S)-2-alkyl-2-amino-3-(methylamino)propanoic and other 2,3-diaminoalkanoic acid derivatives from a chiral imidazoline Liebigs Annalen Der Chemie. 1991: 1323-1336. DOI: 10.1002/Jlac.1991199101227  0.406
1991 Blaser D, Seebach D. Benzyl (R)- and (S)-2-tert-butyl-5-oxo-oxazolidine-3-carboxylate for convenient preparation ofD- andL-threonine analogs from aldehydes Liebigs Annalen Der Chemie. 1991: 1067-1078. DOI: 10.1002/Jlac.1991199101184  0.369
1991 Seebach D, Bürger HM, Schickli CP. Stereoselektive Umsetzungen von rac‐, (R), oder (S)‐5‐Alkyliden‐2‐t‐butyl‐3‐methyl‐4‐oxo‐1‐imidazolidincarbonsäure‐t‐butylestern (chirale 2,3‐Dehydroaminosäure‐Derivate) und Herstellung einiger nichtproteinogener Aminosäuren European Journal of Organic Chemistry. 1991: 669-684. DOI: 10.1002/Jlac.1991199101119  0.396
1991 Schickli CP, Seebach D. Herstellung chiraler elektrophiler Glycin- und (E)-2,3-Dehydroaminosäure-Derivate aus 2-t-Butyl-3-methyl-4-oxo-1-imidazolidincarbonsäure-t-butylester (Boc-BMI) European Journal of Organic Chemistry. 1991: 655-668. DOI: 10.1002/Jlac.1991199101118  0.413
1991 Seebach D, Maestro MA, Sefkow M, Neidlein A, Sternleld F, Adam G, Sommerfeld T. A Highly Convergent Total Synthesis of (+)-Myxovirescine M2. Preliminary Communication Helvetica Chimica Acta. 74: 2112-2118. DOI: 10.1002/Hlca.19910740846  0.368
1991 Seebach D, Ko SY, Kessler H, Köck M, Reggelin M, Schmieder P, Walkinshaw MD, Bölsterli JJ, Bevec D. Thiocyclosporins: Preparation, Solution and Crystal Structure, and Immunosuppressive Activity Helvetica Chimica Acta. 74: 1953-1990. DOI: 10.1002/Hlca.19910740833  0.324
1991 Kinkel JN, Gysel U, Blaser D, Seebach D. Preparative Resolution of Heterocyclic Acetals Derived from Glycine, Mercapto-acetic Acid, ?-Alanine, and Formyl- or Acetylacetic Acid by Recycling Chromatography onChiraspher and Temperature Dependence of Separation Factors Helvetica Chimica Acta. 74: 1622-1635. DOI: 10.1002/Hlca.19910740803  0.365
1991 Gerber C, Seebach D. Dipeptide derivatives with a phosphonate instead of carboxylate terminus by C-alkylation of protected (decarboxy-dipeptidyl)phosphonates Helvetica Chimica Acta. 74: 1373-1385. DOI: 10.1002/Hlca.19910740702  0.325
1991 Thaler A, Seebach D, Cardinaux F. Lithium-Salt Effects in Peptide Synthesis. Part II. Improvement of Degree of Resin Swelling and of Efficiency of Coupling in Solid-Phase Synthesis Helvetica Chimica Acta. 74: 628-643. DOI: 10.1002/Hlca.19910740320  0.314
1991 Thaler A, Seebach D, Cardinaux F. Lithium-Salt Effects in Peptide Synthesis. Part I. Conditions for the Use of Lithium-Salts in Coupling Reactions Helvetica Chimica Acta. 74: 617-627. DOI: 10.1002/Hlca.19910740319  0.323
1991 Seebach D, Bossler H, Gründler H, Shoda S, Wenger R. C-Alkylation of Peptides through Polylithiated and LiCl-Solvated Derivatives Containing Sarcosine Li-Enolate Units Helvetica Chimica Acta. 74: 197-224. DOI: 10.1002/Hlca.19910740121  0.346
1991 Beck AK, Seebach D. Aldol‐ und Michael‐Additionen fluorierter Nitroalkane an Aldehyde, Ketone und α,β‐ungesättigte Carbonylverbindungen1,2) Chemische Berichte. 124: 2897-2911. DOI: 10.1002/Cber.19911241233  0.39
1991 Pietzonka T, Seebach D. Alkylations of (R,R)-2-t-Butyl-6-methyl-1,3-dioxan-4-ones which are not Possible with Lithium Amides may be Achieved with a Schwesinger P4 Base Chemische Berichte. 124: 1837-1843. DOI: 10.1002/Cber.19911240822  0.347
1991 Schmidt B, Seebach D. 2,2‐Dimethyl‐α,α,α′,α′‐tetrakis(β‐naphthyl)‐1,3‐dioxolan‐4,5‐dimethanol (DINOL) for the Titanate‐Mediated Enantioselective Addition of Diethylzinc to Aldehydes Angewandte Chemie. 30: 1321-1323. DOI: 10.1002/Anie.199113211  0.328
1991 Seebach D, Behrendt L, Felix D. Titanate‐Catalyzed Enantioselective Addition of Dialkylzinc Compounds—Generated in situ from Grignard Reagents in Ether—to Aldehydes Angewandte Chemie. 30: 1008-1009. DOI: 10.1002/Anie.199110081  0.333
1991 Schmidt B, Seebach D. Catalytic and Stoichiometric Enantioselective Addition of Diethylzinc to Aldehydes Using a Novel Chiral Spirotitanate Angewandte Chemie International Edition in English. 30: 99-101. DOI: 10.1002/Anie.199100991  0.331
1991 Schmidt B, Seebach D. 2,2‐Dimethyl‐α,α,α′,α′‐tetra(naphth‐2‐yl)‐1,3‐dioxolan‐4,5‐dimethanol (DINOL) für die Titanat‐vermittelte, enantioselektive Addition von Diethylzink an Aldehyde Angewandte Chemie. 103: 1383-1385. DOI: 10.1002/Ange.19911031034  0.311
1991 Seebach D, Behrendt L, Felix D. Titanat‐katalysierte enantioselektive Addition von in situ aus Grignard‐Reagentien in Ether erzeugten Alkylzinkverbindungen an Aldehyde Angewandte Chemie. 103: 991-992. DOI: 10.1002/Ange.19911030820  0.302
1990 Ehrler J, Seebach D. Enantioselektive Verseifungen substituierter, achiraler 3-Acyloxy-propylester mit Lipasen: Herstellung chiraler Derivate von «Tris(hydroxymethyl)methan» European Journal of Organic Chemistry. 1990: 379-388. DOI: 10.1002/Jlac.199019900172  0.389
1990 Vettiger T, Seebach D. Nucleophile Ringöffnung von 1-Nitro-1-cyclopropancarbonsäure-arylestern mit sterisch geschützter, aber elektronisch wirksamer Carbonyl- und Nitrogruppe. Ein neues Prinzip der Aminosäuresynthese European Journal of Organic Chemistry. 1990: 195-201. DOI: 10.1002/Jlac.199019900133  0.401
1990 Seebach D, Adam G, Bussche-Hünnefeld Cvd, Gisi U, Binder H. EPC‐synthesis and fungistatic activity of a gloeosporone analog with an ω‐hydroxybutyl instead of the pentyl side chain on the macrocyclic ring European Journal of Organic Chemistry. 1990: 1007-1012. DOI: 10.1002/Jlac.1990199001182  0.311
1990 Seebach D, Vettiger T, Müller H, Plattner DA, Petter W. Stereoselective hydroxyalkylations of (S)‐2‐azetidinecarboxylic acid European Journal of Organic Chemistry. 1990: 687-695. DOI: 10.1002/Jlac.1990199001129  0.377
1990 Amberg W, Seebach D. Direkte Michael-artige Addition von Si-Gruppen an β-Aryl-α,β-ungesättigte Carbonylverbindungen mit R3SiCl/Bu2Cu(CN)Li2 Chemische Berichte. 123: 2439-2444. DOI: 10.1002/Cber.19901231227  0.353
1990 Amberg W, Seebach D. (2R)-5-Alkyl-2-tert-butyl-6-methyl-4H-1,3-dioxin-4-one als Zwischenprodukte zur Herstellung von α,β,β-trisubstituierten β-Hydroxycarbonsäuren unter Selbstregeneration des stereogenen Zentrums von (R)-3-Hydroxybuttersäure Chemische Berichte. 123: 2429-2438. DOI: 10.1002/Cber.19901231226  0.4
1990 Amberg W, Seebach D. (E,R,R)‐5‐Alkyliden‐2‐tert‐butyl‐6‐methyl‐1,3‐dioxan‐4‐one: Herstellung aus (R)‐3‐Hydroxybuttersäure, Cuprat‐Additionen und Hydrolysen zu 3‐Hydroxycarbonsäuren mit chiralen sekundären Alkylgruppen in 2‐Stellung Chemische Berichte. 123: 2413-2428. DOI: 10.1002/Cber.19901231225  0.379
1990 Hahn E, Maetzke T, Plattner DA, Seebach D. Röntgenstrukturanalyse des dimeren 2,2-Diphenylcyclopropanthiocarbonsäure-S-tert-butylester-Lithium-Enolat · TMEDA-Komplexes: ein „ganz normales” Ester-Enolat und ein „ganz normales” Methylencyclopropan-Derivat Chemische Berichte. 123: 2059-2064. DOI: 10.1002/Cber.19901231018  0.315
1990 Seebach D. Organic Synthesis—Where now? Angewandte Chemie. 29: 1320-1367. DOI: 10.1002/Anie.199013201  0.311
1989 Polt R, Seebach D. Stereoselective alkylation of glycine units in dipeptide derivatives. "Chirality transfer" via a pivalaldehyde N,N-acetal center Journal of the American Chemical Society. 111: 2622-2632. DOI: 10.1021/Ja00189A042  0.58
1989 Seebach D, Adam G, Zibuck R, Simona W, Rouilly M, Meyer WL, Hinton JF, Privett TA, Templeton GE, Heiny DK, Gisi U, Binder H. Gloeosporone – A Macrolide Fungal Germination Self-Inhibitor Total Synthesis and Activity Liebigs Annalen Der Chemie. 1989: 1233-1240. DOI: 10.1002/Jlac.198919890294  0.309
1989 Seebach D, Dziadulewicz E, Behrendt L, Cantoreggi S, Fitzi R. Synthesis of Nonproteinogenic (R)- or (S)-Amino Acids Analogues of Phenylalanine, Isotopically Labelled and Cyclic Amino Acids fromtert-Butyl 2-(tert-Butyl)-3-methyl-4-oxo-1-imidazolidinecarboxylate (Boc-BMI) Liebigs Annalen Der Chemie. 1989: 1215-1232. DOI: 10.1002/Jlac.198919890293  0.412
1989 Seebach D, Brändli U, Müller H, Dobler M, Egli M, Przybylski M, Schneider K. On the Macrolactonization of β-Hydroxy Acids. Crystal structures of the pentolide and the hexolide from (R)-3-hydroxybutanoic acid. Molecular modeling studies of the tetrolide Helvetica Chimica Acta. 72: 1704-1717. DOI: 10.1002/Hlca.19890720807  0.352
1989 Ehrler J, Seebach D. Notiz über mikrobiologische Umsetzungen mit Halobacterium halobium: Reduktion von 3‐Oxobutansäure‐ethylester und Hydrolyse von 3‐Hydroxybutansäure‐ethylester. Cooperative Effekte von Reduktase und Hydrolase Helvetica Chimica Acta. 72: 793-799. DOI: 10.1002/Hlca.19890720420  0.363
1989 Herradón B, Seebach D. Mono- and Dialkylation of Derivatives of (1R, 2S)-2-Hydroxycyclopentanecarboxylic Acid and -cyclohexanecarboxylic acidviabicyclic dioxanones: Selective generation of three contiguous stereogenic centers on a cyclohexane ring Helvetica Chimica Acta. 72: 690-714. DOI: 10.1002/Hlca.19890720410  0.401
1989 Maetzke T, Seebach D. Röntgenstrukturanalyse von 2,4,6‐Tri(tert‐butyl)phenyl‐lithium · N,N,N′,N′‐Tetramethylpropan‐1,2‐diamin: Eine monomere Organolithium‐Verbindung Helvetica Chimica Acta. 72: 624-630. DOI: 10.1002/Hlca.19890720321  0.306
1989 Seebach D, Charczuk R, Gerber C, Renaud P, Berner H, Schneider H. Elektrochemische Decarboxylierung vonL.-Threonin- und Oligopeptid-Derivaten unter Bildung vonN-Acyl-N, O-acetalen: Herstellung von Oligopeptiden mit Carboxamid-oder Phosphonat-C-Terminus Helvetica Chimica Acta. 72: 401-425. DOI: 10.1002/Hlca.19890720302  0.533
1989 Seebach D, Stucky G, Pfammatter E. Cycloadditionen an die Doppelbindung von (R)‐2‐tert‐Butyl‐Δ4‐1,3‐oxazolin‐3‐carbonsäure‐methylestern Chemische Berichte. 122: 2377-2389. DOI: 10.1002/Cber.19891221226  0.379
1989 Stucky G, Seebach D. Substitutionen und Additionen an (R)-2-tert-Butyl-Δ4-1,3-oxazolin-3-carbonsäure-methylester Chemische Berichte. 122: 2365-2375. DOI: 10.1002/Cber.19891221225  0.383
1988 Adam G, Seebach D. (2S,3R)-2-Benzyloxy-3,4-epoxybutan-1-ol, A Versatile Synthetic Building Block Formally Derived From (u)-Tartaric acid Synthesis. 5: 373-375. DOI: 10.1055/S-1988-27577  0.317
1988 Seebach D, Zimmermann J, Gysel U, Ziegler R, Ha TK. Totally stereoselective additions to 2,6-disubstituted 1,3-dioxin-4-ones (chiral acetoacetic acid derivatives). Synthetic and mechanistic aspects of remote stereoselectivity Journal of the American Chemical Society. 110: 4763-4772. DOI: 10.1021/Ja00222A039  0.38
1988 Fitzi R, Seebach D. Resolution and use in α-amino acid synthesis of imidazolidinone glycine derivatives Tetrahedron. 44: 5277-5292. DOI: 10.1016/S0040-4020(01)86036-1  0.397
1988 Betschart C, Schmidt B, Seebach D. Anwendungsbreite der reduktiven Kupplung aromatischer Aldimin‐Derivate mit niedervalenten Titan‐Reagenzien zu 1,2‐Diarylethylendiaminen Helvetica Chimica Acta. 71: 1999-2021. DOI: 10.1002/Hlca.19880710818  0.389
1988 Estermann H, Seebach D. Diastereoselektive Alkylierung von 3‐Aminobutansäure in der 2‐Stellung Helvetica Chimica Acta. 71: 1824-1839. DOI: 10.1002/Hlca.19880710724  0.405
1988 Seebach D, Müller SG, Gysel U, Zimmermann J. Präparative chromatographische Enantiomerentrennung von synthetisch nützlichen cyclischen Acetalen Helvetica Chimica Acta. 71: 1303-1318. DOI: 10.1002/Hlca.19880710541  0.346
1988 Zimmermann J, Seebach D, Ha T. α‐Alkylierung von β‐Hydroxycarbonsäuren über 1,3‐Dioxan‐4‐on‐Enolate Helvetica Chimica Acta. 71: 1143-1155. DOI: 10.1002/Hlca.19880710527  0.389
1988 Seebach D, Maetzke T, Haynes RK, Paddon‐Row MN, Wong SS. Low‐Temperature X‐ray Crystal‐Structure Analysis of the Thermally Unstable Lithiated 2‐Butenyl tert‐Butyl Sulfide: A comparison with model ab initio MO calculations Helvetica Chimica Acta. 71: 299-311. DOI: 10.1002/Hlca.19880710202  0.316
1988 Gander-Coquoz M, Seebach D. Herstellung enantiomerenreiner, α‐alkylierter Lysin‐, Ornithin‐ und Tryptophan‐Derivate Helvetica Chimica Acta. 71: 224-236. DOI: 10.1002/Hlca.19880710124  0.413
1988 Seebach D, Brändli U, Schnurrenberger P, Przybylski M. High-Yield Synthesis of 20-, 24-, and 28-Membered Macropentolide, -hexolide, and -heptolide, Respectively, from (R)- or (S)-3-hydroxybutanoic acid underYamaguchi's macrolactonization conditions Helvetica Chimica Acta. 71: 155-167. DOI: 10.1002/Hlca.19880710119  0.349
1988 Eberle M, Egli M, Seebach D. Enantioselektive Verseifung der Diacetate von 2‐Nitro‐1,3‐diolen mit Schweineleber‐Esterase und Herstellung enantiomerenreiner Derivate von 2‐Nitro‐allylalkoholen (chirale Verknüpfungsreagenzien) Helvetica Chimica Acta. 71: 1-23. DOI: 10.1002/Hlca.19880710102  0.336
1988 SEEBACH D, STUCKY G, RENAUD P. ChemInform Abstract: Chiral Building Blocks from Amino Acids via an Electrochemical Key Step: Synthesis of (R)-2-tert-Butyl-3-methoxycarbonyl-1,3-oxazolines from (S)-Serine and (S)-Threonine. Cheminform. 19. DOI: 10.1002/chin.198842205  0.442
1988 Krause N, Seebach D. The ring opening of unsymmetrical allylic, benzylic, propargylic, and Si-substituted epoxides by titanium acetylides: a convenient access to certain 2-substituted 3-butyn-1-ols Chemische Berichte. 121: 1315-1320. DOI: 10.1002/Cber.19881210716  0.392
1988 Seebach D, Adam G, Gees T, Schiess M, Weigand W. Scope and limitations of the TiCl4-mediated additions of isocyanides to aldehydes and ketones with formation of α-hydroxycarboxylic acid amides Chemische Berichte. 121: 507-517. DOI: 10.1002/Cber.19881210319  0.429
1988 Amberg W, Seebach D. Direct Michael Additions of Silyl Groups to α,β-Unsaturated β-Arylketones and an α-Benzylidenelactone with Mixtures Obtained from Copper(I) Cyanide, Butyllithium and Chlorosilanes Angewandte Chemie. 27: 1718-1719. DOI: 10.1002/Anie.198817181  0.316
1988 Seebach D. Structure and Reactivity of Lithium Enolates. From Pinacolone to SelectiveC-Alkylations of Peptides. Difficulties and Opportunities Afforded by Complex Structures Angewandte Chemie International Edition in English. 27: 1624-1654. DOI: 10.1002/Anie.198816241  0.397
1988 Seebach D, Stucky G. Reactivity of (R)‐2‐tert‐Butyldihydrooxazole Derivatives Prepared from Serine and Threonine: Novel, Versatile Chiral Building Blocks Angewandte Chemie. 27: 1351-1353. DOI: 10.1002/Anie.198813511  0.328
1988 Seebach D. Struktur und Reaktivität von Lithiumenolaten, vom Pinakolon zur selektiven C‐Alkylierung von Peptiden – Schwierigkeiten und Möglichkeiten durch komplexe Strukturen Angewandte Chemie. 100: 1685-1715. DOI: 10.1002/Ange.19881001206  0.31
1988 Seebach D, Stucky G. Reaktivität von (R)‐2‐tert‐Butyldihydrooxazol‐Derivaten aus Serin und Threonin – neuartige und vielseitig einsetzbare chirale Synthesebausteine Angewandte Chemie. 100: 1398-1404. DOI: 10.1002/Ange.19881001021  0.301
1987 Brook MA, Seebach D. Cyclic nitronates from the diastereoselective addition of 1-trimethylsilyloxycyclohexene to nitroolefins. Starting materials for stereoselective Henry reactions and 1,3-dipolar cycloadditions Canadian Journal of Chemistry. 65: 836-850. DOI: 10.1139/V87-142  0.46
1987 Adam G, Zibuck R, Seebach D. Total synthesis of (+)-gloeosporone: assignment of absolute configuration Journal of the American Chemical Society. 109: 6176-6177. DOI: 10.1021/Ja00254A043  0.317
1987 Seebach D, Herradon B. Diastereoselective elaboration of the carbon skeleton of β-hydroxyesters from yeast reductions Preparation of (2S)-2-Hydroxy-cyclohexane Carboxylic Acids with Three Contiguous Stereogenic Centers Tetrahedron Letters. 28: 3791-3794. DOI: 10.1016/S0040-4039(00)96385-8  0.749
1987 Seebach D, Estermann H. α-Alkylation of β-aminobutanoates with lk-1.2-induction Tetrahedron Letters. 28: 3103-3106. DOI: 10.1016/S0040-4039(00)96296-8  0.373
1987 Schnurrenberger P, Hungerbühler E, Seebach D. Total synthesis of (+)-colletodiol from (S,S)-tartrate and (R)-3-hydroxybutanoate European Journal of Organic Chemistry. 1987: 733-744. DOI: 10.1002/Jlac.198719870821  0.308
1987 Betschart C, Seebach D. Aminierende reduktive Kupplung aromatischer Aldehyde mit niervalenten Titan‐Reagenzien zu 1,2‐Diarylethylendiaminen Helvetica Chimica Acta. 70: 2215-2231. DOI: 10.1002/Hlca.19870700826  0.357
1987 Noda Y, Seebach D. Reactions of Chiral 2-(tert-Butyl)-2H,4H-1,3-dioxin-4-ones Bearing Functional Groups in the 6-Position and Diastereoselective Catalytic Hydrogenation tocis-2,6-Disubstituted 1,3-Dioxan-4-ones Helvetica Chimica Acta. 70: 2137-2145. DOI: 10.1002/Hlca.19870700819  0.356
1987 Huber IMP, Seebach D. EPC-Synthesis of Tetrahydroisoquinolines by Diastereoselective Alkylation at the 1-Position of Phenylalanine-Derived Precursors. Synthesis of the Alkaloid (+)-Corlumine Helvetica Chimica Acta. 70: 1944-1954. DOI: 10.1002/Hlca.19870700729  0.42
1987 Polt R, Seebach D. Alkylation of Imidazolidinone Dipeptide Derivatives: Preparation of Enantiomerically Pure Di- and Tripeptides by ?Chirality Transfer?via a Pivalaldehyde N,N-Acetal Center. Preliminary Communication Helvetica Chimica Acta. 70: 1930-1936. DOI: 10.1002/Hlca.19870700727  0.615
1987 Häner R, Olano B, Seebach D. Preparation and C-Alkylation of Enantiomerically PureS-Phenyl Aziridinecarbothioates. On the Structure of Small-Ring Ester Lithium Enolates Helvetica Chimica Acta. 70: 1676-1693. DOI: 10.1002/Hlca.19870700704  0.356
1987 Seebach D, Roggo S, Maetzke T, Braunschweiger H, Cercus J, Krieger M. Diasterio‐ und enantioselektive Reduktion von β‐Ketoestern mit Cyclopentanon‐, Cyclohexanon‐, Piperidon‐ und Tetralon‐Struktur durch nicht fermentierende Bäcker‐Hefe Helvetica Chimica Acta. 70: 1605-1615. DOI: 10.1002/Hlca.19870700618  0.36
1987 Seebach D, Häner R, Vettiger T. Nucleophile Ringöffnung von α‐Nitrocyclopropancarbonsäure‐arylestern mit sterisch geschützter, aber elektronisch wirksamer Carbonyl‐ und Nitro‐Gruppe. Ein neues Prinzip der α‐Aminosäure‐Synthese (2‐Aminobutansäure‐a4‐Synthon) Helvetica Chimica Acta. 70: 1507-1515. DOI: 10.1002/Hlca.19870700607  0.403
1987 Seebach D, Isabelle MPH, Max AS. Diasteroselektive Hydroxyalkylierungen in 1‐Stellung von Tetrahydroisochinolinen und Synthese von Aporphin‐, Protoberberin‐ und Phthalid‐Alkaloider Helvetica Chimica Acta. 70: 1357-1379. DOI: 10.1002/Hlca.19870700517  0.323
1987 Griesbeck A, Seebach D. Herstellung enantiomerenreiner Derivate von 3‐Amino‐ und 3‐Mercaptobuttersäure durch SN2‐Ringöffnung des β‐Lactons und eines 1,3‐Dixoanons aus der 3‐Hydroxybuttersä ure Helvetica Chimica Acta. 70: 1326-1332. DOI: 10.1002/Hlca.19870700514  0.572
1987 Griesbeck A, Seebach D. Einfache Umwandlung von(–)‐(R)‐3‐Hydroxybuttersäure in das (+)‐(S)‐Enantiomere und dessen Lacton(‒)‐(S)‐4‐Methyloxetan‐2‐on Helvetica Chimica Acta. 70: 1320-1325. DOI: 10.1002/Hlca.19870700513  0.545
1987 Seebach D, Aebi JD, Gander-Coquoz M, Naef R. Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung†‡ Helvetica Chimica Acta. 70: 1194-1216. DOI: 10.1002/Hlca.19870700426  0.376
1987 Zimmermann J, Seebach D. Brominations of Cyclic Acetals from ?-Amino Acids and ?- or ?-Hydroxy Acids withN-Bromosucinimide Helvetica Chimica Acta. 70: 1104-1114. DOI: 10.1002/Hlca.19870700423  0.388
1987 Seebach D, Beck AK, Imwinkelzied R, Roggo S, Wonnacott A. Chirale Alkoxytitan(IV)‐Komplexe für enantioselektive nucleophile Additionen an Aldehyde und als Lewis‐Säuren in Diels‐Alder‐Reaktionen Helvetica Chimica Acta. 70: 954-974. DOI: 10.1002/Hlca.19870700406  0.397
1987 Seebach D, Imwinkelried R, Stucky G. Optisch aktive Alkohole aus 1,3-Dioxan-4-onen: eine praktikable Variante der enantioselektiven Synthese unter nucleophiler Substitution an Acetal-Zentren† Helvetica Chimica Acta. 70: 448-464. DOI: 10.1002/Hlca.19870700226  0.395
1987 Renaud P, Hürzeler M, Seebach D. Elektrochemische Oxidation von (S)-Äpfelsäure-Derivaten: ein Weg zu enantiomerenreinen alkylierten Malonaldehydsäure-estern Helvetica Chimica Acta. 70: 292-298. DOI: 10.1002/Hlca.19870700204  0.506
1987 Seebach D, Juaristi E, Miller DD, Schickli C, Weber T. Addition of Chiral Glycine, Methionine, and Vinylglycine Enolate Derivatives to Aldehydes and Ketones in the Preparation of Enantiomerically Pure ?-Amino-?-Hydroxy Acids Helvetica Chimica Acta. 70: 237-261. DOI: 10.1002/Hlca.19870700129  0.406
1987 GRIESBECK A, SEEBACH D. ChemInform Abstract: Preparation of Enantiomerically Pure Derivatives of 3-Amino- and 3-Mercaptobutanoic Acid by SN2 Ring Opening of the β-Lactone and a 1,3-Dioxanone Derived from 3-Hydroxybutanoic Acid. Cheminform. 18. DOI: 10.1002/chin.198747139  0.539
1987 GRIESBECK A, SEEBACH D. ChemInform Abstract: Simple Conversion of (R)-3-Hydroxybutanoic Acid to the (S)-Enantiomer and Its Lactone (-)-(S)-4-Methyloxetan-2-one. Cheminform. 18. DOI: 10.1002/chin.198747079  0.47
1987 Krause N, Seebach D. Zur Chemie acetylenischer Titan- Verbindungen Chemische Berichte. 120: 1845-1851. DOI: 10.1002/Cber.19871201112  0.379
1986 Renaud P, Seebach D. Electrochemical Decarboxylation of Hydroxyproline: A Simple Three-Step Conversion of (2S,4R)-4-Hydroxyproline to (R)-γ-Amino-β-hydroxybutanoic Acid (GABOB) Synthesis. 1986: 424-426. DOI: 10.1055/S-1986-31665  0.514
1986 Meyer WL, Brannon MJ, Merritt A, Seebach D. Annulation of 2-formyl-2-cyclohexenones by reaction with enamines Tetrahedron Letters. 27: 1449-1452. DOI: 10.1016/S0040-4039(00)84282-3  0.369
1986 Schregenberger C, Seebach D. Totalsynthese des Makrodiolids (+)‐Conglobatin European Journal of Organic Chemistry. 1986: 2081-2103. DOI: 10.1002/Jlac.198619861204  0.359
1986 Seebach D, Chow H, Jackson RFW, Sutter MA, Thaisrivongs S, Zimmermann J. (+)-11,11′-Di-O-methylelaiophylidene – preparation from elaiophylin and total synthesis from (R)-3-hydroxybutyrate and (S)-malate Liebigs Annalen Der Chemie. 1986: 1281-1308. DOI: 10.1002/Jlac.198619860714  0.383
1986 Renaud P, Seebach D. Enantiomerenreine Pyrrolidin-Derivate austrans-4-Hydroxy-L-prolin durch elektrochemische oxidative Decarboxylierung und Titantetrachlorid-vermittelte Umsetzung mit Nukleophilen Helvetica Chimica Acta. 69: 1704-1710. DOI: 10.1002/Hlca.19860690726  0.483
1986 Häner R, Maetzke T, Seebach D. Generation and Reactions of Lithiatedtert-Butyl and 2,6-Di(tert-butyl)-4-methylphenyl Cyclopropanecarboxylates Helvetica Chimica Acta. 69: 1655-1665. DOI: 10.1002/Hlca.19860690720  0.361
1986 Weber T, Aeschimann R, Maetzke T, Seebach D. Methionin als Vorläufer zur enantioselektiven Synthese α-verzweigter Vinylglycine und anderer Aminosäuren Helvetica Chimica Acta. 69: 1365-1377. DOI: 10.1002/Hlca.19860690611  0.42
1986 Seebach D, Zimmermann J. 1,3-Dioxanone Derivatives from ?-Hydroxy-carboxylic Acids and Pivalaldehyde. Versatile Building Blocks for Syntheses of Enantiomerically Pure Compounds. A Chiral Acetoacetic Acid Derivative Preliminary Communication Helvetica Chimica Acta. 69: 1147-1152. DOI: 10.1002/Hlca.19860690523  0.409
1986 Chow H, Seebach D. Diastereoselective aldol addition using boron trichloride or alkoxydichloroborane Helvetica Chimica Acta. 69: 604-614. DOI: 10.1002/Hlca.19860690309  0.373
1986 WEBER T, AESCHIMANN R, MAETZKE T, SEEBACH D. ChemInform Abstract: Methionine as Precursor for the Enantioselective Synthesis of α-Branched Vinylglycines and of Other Amino Acids. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198652120  0.377
1986 HAENER R, SCHWEIZER WB, SEILER P, SEEBACH D. ChemInform Abstract: Aldol Addition of a Lithium Ketone Enolate with Persubstituted Double Bond. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198644065  0.304
1986 Chow H‐, Seebach D. Diastereoselective Aldol Addition Using Boron Trichloride or Alkoxydichloroborane. Cheminform. 17. DOI: 10.1002/Chin.198631107  0.313
1986 Fitzi R, Seebach D. Enantiomer Separation of (R,S)‐2‐(tert‐Butyl)‐3‐methyl‐4‐imidazolidinone, a Chiral Building Block for Amino Acid Synthesis. Cheminform. 17. DOI: 10.1002/Chin.198631106  0.343
1986 SEEBACH D, BECK AK, RENAUD P. ChemInform Abstract: Di- and Trifluoro Substituted Dilithio Compounds for Organic Synthesis. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198619263  0.466
1986 Brändli U, Eyer M, Seebach D. Regioselektive Erzeugung und diastereoselektive Umsetzungen in β-Stellung zur Nitrogruppe sekundärer Nitroalkane über α,β-doppelt deprotonierte Derivate (Super-enamine) Chemische Berichte. 119: 575-588. DOI: 10.1002/Cber.19861190221  0.416
1986 Renaud P, Seebach D. Preparation of Chiral Building Blocks from Amino Acids and Peptides via Electrolytic Decarboxylation and TiCl4-Induced Aminoalkylation Angewandte Chemie International Edition in English. 25: 843-844. DOI: 10.1002/Anie.198608431  0.528
1986 Fitzi R, Seebach D. Enantiomer Separation of(R,S)-2-(tert-Butyl)-3-methyl-4-imidazolidinone, a Chiral Building Block for Amino Acid Synthesis Angewandte Chemie International Edition in English. 25: 345-346. DOI: 10.1002/Anie.198603451  0.36
1986 Seebach D, Beck AK, Renaud P. Di- and Trifluoro-Substituted Dilithium Compounds for Organic Syntheses Angewandte Chemie International Edition in English. 25: 98-99. DOI: 10.1002/Anie.198600981  0.448
1986 Renaud P, Seebach D. Herstellung chiraler Synthesebausteine aus Aminosäuren und Peptiden durch oxidative elektrolytische Decarboxylierung und TiCl4-induzierte Umsetzung mit Nucleophilen Angewandte Chemie. 98: 836-838. DOI: 10.1002/Ange.19860980927  0.424
1986 Seebach D, Imwinkelried R, Stucky G. Optisch aktive Alkohole aus 1,3-Dioxan-4-onen; eine praktikable Variante der asymmetrischen Synthese unter nucleophiler Substitution an Acetalzentren Angewandte Chemie. 98: 182-183. DOI: 10.1002/Ange.19860980220  0.338
1986 Seebach D, Beck AK, Renaud P. Di- und trifluorsubstituierte Dilithium-Verbindungen für die Organische Synthese Angewandte Chemie. 98: 96-97. DOI: 10.1002/Ange.19860980121  0.461
1985 Seebach D, Amstutz R, Laube T, Bernd Schweizer W, Dunitz JD. Structures of three lithium ester enolates by X-ray diffraction: Derivation of reaction path for cleavage into ketene and alcoholate Journal of the American Chemical Society. 107: 5403-5409. DOI: 10.1021/Ja00305A014  0.369
1985 Seebach D, Calderari G, Knochel P. Trifluoroacetoxy-phenylselenation of nitroolefins regioselective preparation of nitroallylic alcohol derivatives and their use as multiple coupling reagents Tetrahedron. 41: 4861-4872. DOI: 10.1016/S0040-4020(01)96725-0  0.445
1985 Seebach D, Hansen J, Seiler P, Gromek JM. On the steric course of addition of 1-lithio- and 1-magnesio-2-pivaloyl-1,2,3,4-tetrahydroisoquinoline to aldehydes and ketones. An x-ray crystal structure determination of the organomagnesium reagent Journal of Organometallic Chemistry. 285: 1-13. DOI: 10.1016/0022-328X(85)87352-6  0.306
1985 Jackson RFW, Sutter MA, Seebach D. Preparation of (2E,4E,6S,7S,10E,12E,14S,15S,1′S)‐7,15‐Bis(1′‐hydroxymethylethyl)‐6,14‐dimethyl‐8,16‐dioxa‐2,4,10,12‐cyclohexadecatetraene‐1,9‐dione. – A Building Block for the Synthesis of Elaiophylin European Journal of Organic Chemistry. 1985: 2313-2327. DOI: 10.1002/Jlac.198519851203  0.336
1985 Seebach D, Renaud P. Chirale Synthesebausteine durchKolbe-Elektrolyse enantiomerenreiner ?-Hydroxy-carbons�urederivate. (R)- und (S)-Methyl-sowie (R)-Trifluormethyl-?-butyrolactone und -?-valerolactone Helvetica Chimica Acta. 68: 2342-2349. DOI: 10.1002/Hlca.19850680829  0.51
1985 Calderari G, Seebach D. Asymmetrische Michael‐Additionen. Stereoselektive Alkylierung chiraler, nicht racemischer Enolate durch Nitroolefine. Herstellung enantiomerenreiner γ‐Aminobuttersäure‐ und Bernsteinsäure‐Derivate Helvetica Chimica Acta. 68: 1592-1604. DOI: 10.1002/Hlca.19850680611  0.398
1985 Aebi JD, Seebach D. Enantioselektive α‐Alkylierung von Asparagin‐ und Glutaminsäure über die Dilithium‐enolatocarboxylate von 2‐[3‐Benzoyl‐2‐(tert‐butyl)‐1‐methyl‐5‐oxoimidazolidin‐4‐yl]essigsäure und 3‐[3‐Benzoyl‐2‐(tert‐butyl)‐1‐methyl‐5‐oxoimidazolidin‐4‐yl]propionsäure Helvetica Chimica Acta. 68: 1507-1518. DOI: 10.1002/Hlca.19850680603  0.37
1985 Laube T, Dunitz JD, Seebach D. Über die Wechselwirkung zwischen Lithium-enolaten und sekundären Aminen in Lösung und im Kristall Helvetica Chimica Acta. 68: 1373-1393. DOI: 10.1002/Hlca.19850680530  0.337
1985 Ertaş M, Seebach D. Selektive Herstellung von l‐ oder u‐Aldolen aus Äthyl‐trityl‐keton und aromatischen Aldehyden über Lithium‐ bzw. Aluminium‐Enolate Helvetica Chimica Acta. 68: 961-968. DOI: 10.1002/Hlca.19850680421  0.349
1985 Seebach D, Miller DD, Müller S, Weber T. The Chiral Glycine Enolate Derivative from 1‐Benzoyl‐2‐(tert‐butyl)‐3‐methyl‐1,3‐imidazolidin‐4‐one is Alkylated in the 5‐Position with Relative Topicity lk. Preliminary Communication Helvetica Chimica Acta. 68: 949-952. DOI: 10.1002/Hlca.19850680418  0.386
1985 Seebach D, Brook MA. Reversed Stereochemical Course of theMichael Addition of Cyclohexanone to ?-Nitrostyrenes by Using 1-(Trimethylsiloxy)cyclohexene/Dichloro(diisopropoxy)titanium. Preliminary Communication Helvetica Chimica Acta. 68: 319-324. DOI: 10.1002/Hlca.19850680205  0.552
1985 Seebach D, Ertas̨ M, Locher R, Schweizer WB. Tritylketone und tritylenone. Beiträge zur sterisch erzwungenen Michael-Addition und zur diastereoselektiven Aldol-Addition Helvetica Chimica Acta. 68: 264-282. DOI: 10.1002/Hlca.19850680133  0.365
1985 Seebach D, Beck AK, Goliński J, Hay JN, Laube T. Über den sterischen Verlauf der Umsetzung von Enaminen aus offenkettigen Aldehyden und Ketonen mit Nitroolefinen zu 2,3‐disubstituierten 4‐Nitroketonen Helvetica Chimica Acta. 68: 162-172. DOI: 10.1002/Hlca.19850680120  0.368
1985 Weber T, Seebach D. Alkylierung in der 2‐Stellung von (2S, 4R)‐ 4‐Hydroxyprolin unter Retention Helvetica Chimica Acta. 68: 155-161. DOI: 10.1002/Hlca.19850680119  0.374
1985 Seebach D, Aebi JD, Naef R, Weber T. α‐Alkylation of Amino Acids without Racemization. Preparation of Either (S)‐ or (R)‐α‐Methyldopa from (S)‐Alanine Helvetica Chimica Acta. 68: 144-154. DOI: 10.1002/Hlca.19850680118  0.399
1985 Naef R, Seebach D. Herstellung enantiomerenreiner cis‐ oder trans‐konfigurierter 2‐(tert‐Butyl)‐3‐methylimidazolidin‐4‐one aus den Aminosäuren (S)‐Alanin, (S)‐Phenylalanin, (R)‐Phenylglycin, (S)‐Methionin und (S)‐Valin Helvetica Chimica Acta. 68: 135-143. DOI: 10.1002/Hlca.19850680117  0.397
1985 Haener R, Laube T, Seebach D. Regio- and diastereoselective preparation of aldols from .alpha.-branched ketone enolates generated from BHT ester enolates and organolithium reagents. In situ generation and trapping of ketenes from ester enolates Journal of the American Chemical Society. 107: 5396-5403. DOI: 10.1002/Chin.198552167  0.318
1985 Seebach D, Chow HF, Jackson R, Lawson K, Sutter M, Thaisrivongs S, Zimmermann J. Total synthesis of (+)-11,11'-di-O-methylelaiophylidene, an aglycon of elaiophylin Journal of the American Chemical Society. 107: 5292-5293. DOI: 10.1002/Chin.198551323  0.512
1985 Seebach D, Beck AK, Roggo S, Wonnacott A. Enantioselective Addition Of Aryl Groups To Aromatic Aldehydes Using Chiral Aryltitanium Binaphthol Derivatives Cheminform. 16. DOI: 10.1002/Chin.198551086  0.32
1985 Seebach D, Fadel A. N,O-Acetals from Pivalaldehyde and Amino Acids for the ?-Alkylation with Self-Reproduction of the Center of Chirality. Enolates of 3-Benzoyl-2-(tert-butyl)-1,3-oxazolidin-5-ones Helvetica Chimica Acta. 68: 1243-1250. DOI: 10.1002/Chin.198547296  0.32
1985 SEEBACH D, CALDERARI G, MEYER WL, MERRITT A, ODERMANN L. ChemInform Abstract: STEREOSELECTIVE (3 + 3)-CARBOCYCLIZATION OF ENAMINES WITH NITROALLYLATING REAGENTS Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198547090  0.363
1985 SEEBACH D, MILLER DD, MUELLER S, WEBER T. ChemInform Abstract: THE CHIRAL GLYCINE ENOLATE DERIVATIVE FROM 1-BENZOYL-2-(TERT-BUTYL)-3-METHYL-1,3-IMIDAZOLIDIN-4-ONE IS ALKYLATED IN THE 5-POSITION WITH RELATIVE TOPICITY LK Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198539200  0.35
1985 WIDLER L, WEBER T, SEEBACH D. ChemInform Abstract: THE D1- AND D3-SELECTIVE REACTIONS OF SULFUR-SUBSTITUTED ALLYLIC TITANIUM DERIVATIVES WITH ALDEHYDES AND KETONES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198532091  0.311
1985 Seebach D, Aebi JD, Naef R, Weber T. α-ALKYLATION OF AMINO ACIDS WITHOUT RACEMIZATION. PREPARATION OF EITHER (S)- OR (R)-α-METHYLDOPA FROM (S)-ALANINE Cheminform. 16. DOI: 10.1002/Chin.198522350  0.356
1985 Seebach D, Beck AK, Roggo S, Wonnacott A. Enantioselektive Addition von Arylgruppen an aromatische Aldehyde mit Aryltitan‐Binaphthol‐Derivaten Chemische Berichte. 118: 3673-3682. DOI: 10.1002/Cber.19851180921  0.385
1985 Widler L, Weber T, Seebach D. d1- und d3-selektive Umsetzungen von schwefelsubstituierten Allyl-Titan-Derivaten mit Aldehyden und Ketonen Chemische Berichte. 118: 1329-1344. DOI: 10.1002/Cber.19851180405  0.364
1984 Schregenberger C, Seebach D. Synthesis and determination of the absolute configuration of the macrodiolide (+)-conglobatin Tetrahedron Letters. 25: 5881-5884. DOI: 10.1016/S0040-4039(01)81710-X  0.398
1984 Seebach D, Züger MF. On the preparation of methyl and ethyl (r)-(−)-3-hydroxy-valerate by depolymerization of a mixed phb/phv biopolymer Tetrahedron Letters. 25: 2747-2750. DOI: 10.1016/S0040-4039(01)81280-6  0.339
1984 Seebach D, Aebi JD. α-alkylation of serine with self-reproduction of the center of chirality Tetrahedron Letters. 25: 2545-2548. DOI: 10.1016/S0040-4039(01)81227-2  0.362
1984 Schnurrenberger P, Hungerbühler E, Seebach D. (+)-Colletodiol : Synthesis from (S,S)-tartaric acid and (R)-3-hydroxy-butyric acid Tetrahedron Letters. 25: 2209-2212. DOI: 10.1016/S0040-4039(01)80212-4  0.319
1984 Seebach D, Naef R, Calderari G. (α-Alkylation of α-heterosubstituted carboxylic acids without racemization : EPC-syntheses of tertiary alcohols and thiols☆☆☆ Tetrahedron. 40: 1313-1324. DOI: 10.1016/S0040-4020(01)82417-0  0.378
1984 Bauer W, Seebach D. Bestimmung des Aggregationsgrads lithiumorganischer Verbindungen durch Kryoskopie in Tetrahydrofuran Helvetica Chimica Acta. 67: 1972-1988. DOI: 10.1002/Hlca.19840670736  0.383
1984 Seebach D, Weber T. Hydroxyalkylierungen von Cystein über das Enolat von (2R,5R)‐2(tert‐Butyl)‐1‐aza‐3‐oxa‐7‐thiabicyclo[3.3.0]octan‐4‐on und unter Selbstreproduktion des Ciralitätszentrums Helvetica Chimica Acta. 67: 1650-1661. DOI: 10.1002/Hlca.19840670635  0.428
1984 Seebach D, Betschart C, Schiess M. Diastereoselektive synthese neuartiger Mannich-Basen mittels titanderivaten, vorläufige mitteilung†‡ Helvetica Chimica Acta. 67: 1593-1597. DOI: 10.1002/Hlca.19840670626  0.372
1984 Imwinkelried R, Seebach D. Aminierende, reduktive Kupplung aromatischer Aldehyde mit Tris(dialkylamino)methylvanandium (IV) zu N,N,N′,N′‐Tetraaalkyl‐1,2‐diaryläthylendiaminen Helvetica Chimica Acta. 67: 1496-1502. DOI: 10.1002/Hlca.19840670612  0.329
1984 Nájera C, Yus M, Hässig R, Seebach D. Fluoro(phenylsufinyl)methyllithium. Note on the 13C‐NMR Spectrum of a Flourocarbenoid Helvetica Chimica Acta. 67: 1100-1103. DOI: 10.1002/Hlca.19840670422  0.427
1984 Seebach D, Gabriel J, Hässig R. Low-Temperature 13C-NMR Spectra of 6Li- and 13C-Labelled Sulfur- and Selenium-Substituted Organolithium Derivatives†‡§ Helvetica Chimica Acta. 67: 1083-1099. DOI: 10.1002/Hlca.19840670421  0.302
1984 Gabriel J, Seebach D. Synthese und NMR‐Spektren einiger 13C‐markierter Thio‐ und Seleno‐äther, ‐acetale und ‐orthoester Helvetica Chimica Acta. 67: 1070-1082. DOI: 10.1002/Hlca.19840670420  0.345
1984 Nájera C, Yus M, Seebach D. C‐Metallierte chirale Aloxide als d2‐ und d3‐Reagenzien für die Synthese enantiomerenreiner Produkte (EPC‐Synthese) Helvetica Chimica Acta. 67: 289-300. DOI: 10.1002/Hlca.19840670135  0.503
1984 Seebach D, Konchel P. 2'-Nitro-2'-propen-1'-yl 2,2-dimethylpropanoate (NPP), a multiple coupling reagent Helvetica Chimica Acta. 67: 261-283. DOI: 10.1002/Hlca.19840670133  0.344
1984 Seebach D, Renaud P, Schweizer WB, Züger MF, Brienne M. Preparation by yeast reduction and determination of the sense of chirality of enantiomerically pure ethyl (−)-4,4,4-trichloro-3-hydroxy- and (+)-4,4,4-trifluoro-3-hydroxybutanoate Helvetica Chimica Acta. 67: 1843-1853. DOI: 10.1002/Chin.198507084  0.469
1984 SEEBACH D, BETSCHART C, SCHIESS M. ChemInform Abstract: DIASTEREOSELECTIVE SYNTHESIS OF NOVEL MANNICH BASES THROUGH TITANIUM DERIVATIVES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198452114  0.356
1984 Najera C, Yus M, Haessig R+, Seebach D. Fluoro(Phenylsulfinyl)Methyllithium. Note On The Carbon‐13 Nmr Spectrum Of A Fluorocarbenoid Cheminform. 15. DOI: 10.1002/Chin.198440047  0.417
1984 HAESSIG R, SEEBACH D, SIEGEL H. ChemInform Abstract: PREPARATION OF ALLENES FROM GEMINAL DIBROMO OLEFINS AND ALDEHYDES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198432137  0.359
1984 SEEBACH D, ZUEGER MF, GIOVANNINI F, SONNLEITNER B, FIECHTER A. ChemInform Abstract: PREPARATIVE MICROBIOLOGICAL REDUCTION OF β-OXO ESTERS WITH THERMOANAEROBIUM BROCKII Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198419094  0.343
1984 NAJERA C, YUS M, SEEBACH D. ChemInform Abstract: C-METALATED CHIRAL ALKOXIDES AS D2- AND D3-REAGENTS FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE COMPOUNDS (EPC-SYNTHESIS) Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198416153  0.47
1984 ZUEGER MF, GIOVANNINI F, SEEBACH D. ChemInform Abstract: PREPARATION OF ETHYL (R)-(-)-3-HYDROXY-2-METHYLPROPIONATE BY YEAST REDUCTION OF ETHYL α-FORMYLPROPIONATE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198412146  0.348
1984 AEBI JD, SUTTER MA, WASMUTH D, SEEBACH D. ChemInform Abstract: ENANTIOMERICALLY PURE SYNTHONS FROM BRANCHED MALATES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198410067  0.309
1984 Hässig R, Seebach D, Siegel H. Herstellung von Allenen aus geminalen Dibromolefinen und Aldehyden Chemische Berichte. 117: 1877-1884. DOI: 10.1002/Cber.19841170515  0.327
1984 Seebach D, Dust M, Naef R, Bänziger M. Synthesis and Determination of the Absolute Configuration of (+)-Delesserine, a Metabolite of the Red Marine AlgaDelesseria sanguinea(Lamouroux) Angewandte Chemie International Edition in English. 23: 530-531. DOI: 10.1002/Anie.198405301  0.303
1984 Seebach D, Syfrig MA. Diastereoselective Hydroxyalkylation of the 1‐Position of 2‐Pivaloyl 1,2,3,4‐tetrahydroisoquinoline via Magnesium Derivatives Angewandte Chemie. 23: 248-249. DOI: 10.1002/Anie.198402481  0.321
1984 Seebach D, Dust M, Naef R, Bänziger M. Synthese und Bestimmung der absoluten Konfiguration von (+)-Delesserin, einem Inhaltsstoff der roten Meeresalge Delesseria sanguinea (Lamouroux) Angewandte Chemie. 96: 498-498. DOI: 10.1002/Ange.19840960710  0.308
1983 Seebach D, Beck AK, Schiess M, Widler L, Wonnacott A. Some recent advances in the use of titanium reagents for organic synthesis Pure and Applied Chemistry. 55: 1807-1822. DOI: 10.1351/Pac198355111807  0.405
1983 Thaisrivongs S, Seebach D. Diastereoselective benzyloxymercuration/demercuration of derivatives of .gamma.-alkyl-.delta.-hydroxy-.alpha.,.beta.-unsaturated esters. A new strategy for the synthesis of aldol-type products Journal of the American Chemical Society. 105: 7407-7413. DOI: 10.1021/Ja00363A033  0.318
1983 Seebach D, Boes M, Naef R, Schweizer WB. Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality Journal of the American Chemical Society. 105: 5390-5398. DOI: 10.1021/Ja00354A034  0.336
1983 Seebach D, Weber T. α-Alkylation of a cysteine derivative without racemization and without the use of a chiral auxiliary Tetrahedron Letters. 24: 3315-3318. DOI: 10.1016/S0040-4039(00)86257-7  0.353
1983 Seebach D, Aebi JD. α-Alkylation of threonine Tetrahedron Letters. 24: 3311-3314. DOI: 10.1016/S0040-4039(00)86256-5  0.339
1983 Seebach D, Lohmann J, Syfrig MA, Yoshifuji M. Alkylation of the isoquinoline skeleton in the 1-position Tetrahedron. 39: 1963-1974. DOI: 10.1016/S0040-4020(01)91914-3  0.346
1983 Aebi JD, Sutter MA, Wasmuth D, Seebach D. Enantiomerenreine Synthesebausteine aus verzweigter Äpfelsäure European Journal of Organic Chemistry. 1983: 2114-2126. DOI: 10.1002/Jlac.198319831207  0.336
1983 Naef R, Seebach D. Vierstufige EPC-Synthese von (+)- oder (−)-Frontalin aus Milchsäure. – Eine erste Anwendung des Prinzips der Selbstreproduktion der Chiralität in der Naturstoffsynthese European Journal of Organic Chemistry. 1983: 1930-1936. DOI: 10.1002/Jlac.198319831108  0.391
1983 Sutter MA, Seebach D. Synthese von (2E,4E,6S,7R,10E,12E,14S,15R)‐6,7,14,15‐Tetramethyl‐8,16‐dioxa‐2,4,10,12‐cyclohexadecatetraen‐1,9‐dion. Ein Modellsystem für Elaiophylin European Journal of Organic Chemistry. 1983: 939-949. DOI: 10.1002/Jlac.198319830607  0.309
1983 Schiess M, Seebach D. N-Methyl-C-(trichlortitanio)formimidoylchlorid. Ein effizientes Reagenz zur Homologisierung von Aldehyden und Ketonen zu α-Hydroxy-carbonsäureamiden Helvetica Chimica Acta. 66: 1618-1623. DOI: 10.1002/Hlca.19830660531  0.382
1983 Seebach D, Hässig R, Gabriel J. 13C‐NMR.‐Spektroskopie von Organolithiumverbindungen bei tiefen Temperaturen. Strukturinformation aus der 13C, 6Li‐Kopplung Helvetica Chimica Acta. 66: 308-337. DOI: 10.1002/Hlca.19830660128  0.313
1983 SEEBACH D, BOES M, NAEF R, SCHWEIZER WB. ChemInform Abstract: ALKYLATION OF AMINO ACIDS WITHOUT LOSS OF THE OPTICAL ACTIVITY: PREPARATION OF α-SUBSTITUTED PROLINE DERIVATIVES. A CASE OF SELF-REPRODUCTION O CHIRALITY Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198347110  0.344
1983 SEEBACH D, WIDLER L. ChemInform Abstract: A CASE OF HIGHLY DIASTEREOSELECTIVE ADDITION TO UNSYMMETRICAL KETONES: LK-ADDITION OF (2-ALKENYL)TRIPHENOXYTITANIUM DERIVATIVES Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198314107  0.329
1983 Blarer SJ, Seebach D. Asymmetrische Michael‐Additionen. Regio‐, diastereo‐ und enantioselektive Alkylierungen der Enamine aus β‐Tetralonen und (S)‐2‐(Methoxymethyl)pyrrolidin („Prolinolmethylether”︁) durch ω‐Nitrostyrole Chemische Berichte. 116: 3086-3096. DOI: 10.1002/Cber.19831160908  0.365
1983 Blarer SJ, Seebach D. Asymmetrische Michael‐Additionen. Stereoselektive Alkylierungen des (R)‐ und (S)‐Enamins aus Cyclohexanon und 2‐(Methoxymethyl)pyrrolidin durch α‐(Methoxycarbonyl)zimtsäure‐methylester Chemische Berichte. 116: 2250-2260. DOI: 10.1002/Cber.19831160616  0.37
1983 Züger MF, Giovannini F, Seebach D. Preparation of Ethyl (R)-(−)-3-Hydroxy-2-methylpropanoate by Yeast Reduction of Ethyl α-Formylpropanoate Angewandte Chemie International Edition in English. 22: 1012-1012. DOI: 10.1002/Anie.198310121  0.332
1983 Weidmann B, Seebach D. Organometallverbindungen von Titan und Zirconium als selektive nucleophile Reagentien für die Organische Synthese Angewandte Chemie. 95: 12-26. DOI: 10.1002/Ange.19830950103  0.331
1982 Knochel P, Seebach D. Dehydratisierung von Nitroaldolen mit Dicyclohexylcarbodiimid: Herstellung von Nitroolefinen unter milden Bedingungen Synthesis. 1982: 1017-1018. DOI: 10.1055/S-1982-30045  0.334
1982 Knochel P, Seebach D. Synthesis and reactions of substituted nitro-allylating reagents Tetrahedron Letters. 23: 3897-3900. DOI: 10.1016/S0040-4039(00)87737-0  0.489
1982 Weller T, Seebach D. Synthesis of (±)-1-desoxy-2-lycorinone and of a possible trans-dihydro-lycoricidine precursor Tetrahedron Letters. 23: 935-938. DOI: 10.1016/S0040-4039(00)86987-7  0.349
1982 Seidel W, Seebach D. Crahamimycin A1 synthesis and determination of configuration and chirality Tetrahedron Letters. 23: 159-162. DOI: 10.1016/S0040-4039(00)86774-X  0.319
1982 Seebach D, Schiess M. Alkylative amination of non-enolizable aldehydes with alkyl (dialkyl-amino)titanium derivatives† Preliminary Communication Helvetica Chimica Acta. 65: 2598-2602. DOI: 10.1002/Hlca.19820650831  0.325
1982 Seebach D, Widler L. A case of highly diastereoselective addition to unsymmetrical ketones: lk-addition† of (2-alkenyl)triphenoxytitanium derivatives Helvetica Chimica Acta. 65: 1972-1981. DOI: 10.1002/Hlca.19820650704  0.388
1982 Blarer SJ, Schweizer WB, Seebach D. Asymmetrische Micheal‐Additionen. Praktisch vollständigdiastereo‐ und enantioselektive Alkylierungen des Enamins aus Cyclohexanon und Prolinylmethyläther.durch ω‐Nitrostyrole zu u‐2‐(l′‐Aryl‐2′‐nitroäthyl)cyclohexanonen Helvetica Chimica Acta. 65: 1637-1654. DOI: 10.1002/Hlca.19820650537  0.355
1982 Seebach D, Züger M. Über die Depolymerisierung von Poly-(R)-3-hydroxy-buttersäureester (PHB) Helvetica Chimica Acta. 65: 495-503. DOI: 10.1002/Hlca.19820650208  0.372
1982 Wasmuth D, Arigoni D, Seebach D. Zum stereochemischen Verlauf der Biosynthese von 2-Oxo-pantolacton: Synthese von stereospezifisch indiziertem Pantolacton aus Äpfelsäure Helvetica Chimica Acta. 65: 344-352. DOI: 10.1002/Hlca.19820650136  0.368
1982 SEEBACH D, PRELOG V. ChemInform Abstract: SPECIFICATION OF THE STERIC COURSE OF ASYMMETRIC SYNTHESES Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198250357  0.511
1982 BLARER SJ, SCHWEIZER WB, SEEBACH D. ChemInform Abstract: ASYMMETRIC MICHAEL ADDITIONS. PRACTICALLY COMPLETELY DIASTEREO- AND ENANTIOSELECTIVE ALKYLATIONS OF THE ENAMINE FROM CYCLOHEXANONE AND PROLINYL METHYL ETHER BY Ω-NITROSTYRENES TO GIVE U-2-(1′-ARYL-2′-NITROETHYL)CYCLOHEXANONES Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198249096  0.344
1982 Seebach D, Beck AK, Mukhopadhyay T, Thomas E. Diastereoselective Synthesis of Nitroaldol Derivatives Helvetica Chimica Acta. 65: 1101-1133. DOI: 10.1002/Chin.198244109  0.356
1982 HAESSIG R, SIEGEL H, SEEBACH D. ChemInform Abstract: PREPARATION OF SUBSTITUTED METHYLENECYCLOPROPANES FROM GEMINAL-DIBROMOCYCLOPROPANES AND CARBONYL COMPOUNDS Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198232129  0.325
1982 Seebach D, Pohmakotr M, Schregenberger C, Weidmann B, Mali RS, Pohmakotr S. d5-Reactions of Doubly Deprotonated ?,?-Unsaturated Carbonyl Derivatives with Electrophiles. A Novel Approach to the Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives Helvetica Chimica Acta. 65: 419-450. DOI: 10.1002/Chin.198231207  0.338
1982 Kai Y, Knochel P, Kwiatkowski S, Dunitz JD, Oth JFM, Seebach D, Kalinowski H. Structure, Synthesis, and Properties of Some Persubstituted 1,2-Dintroethanes. In Quest of Nitrocyclopropyl-Anion Derivatives Helvetica Chimica Acta. 65: 137-161. DOI: 10.1002/Chin.198223164  0.411
1982 WASMUTH D, ARIGONI D, SEEBACH D. ChemInform Abstract: STEREOCHEMICAL PATH OF THE BIOSYNTHESIS OF 2-OXOPANTOLACTONE: SYNTHESIS OF STEREOSPECIFICALLY LABELED PANTOLACTONE FROM MALIC ACID Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198223106  0.327
1982 Mukhopadhyay T, Seebach D. Substitution of HMPT by the cyclic urea DMPU as a cosolvent for highly reactive nucleophiles and bases Helvetica Chimica Acta. 65: 385-391. DOI: 10.1002/Chin.198222157  0.351
1982 Seebach D, Naef R. ENANTIOSELECTIVE GENERATION AND DIASTEREOSELECTIVE REACTIONS OF CHIRAL ENOLATES DERIVED FROM α-HETEROSUBSTITUTED CARBOXYLIC ACIDS. PRELIMINARY COMMUNICATION Cheminform. 13. DOI: 10.1002/Chin.198215113  0.347
1982 OLIVERO AG, WEIDMANN B, SEEBACH D. ChemInform Abstract: ENANTIOSELECTIVE ADDITION OF CHIRAL ORGANOTITANIUM DERIVATIVES TO ALDEHYDES. PRELIMINARY COMMUNICATION Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198213267  0.314
1982 Hässig R, Siegel H, Seebach D. Herstellung von substituierten Methylencyclopropanen aus geminalen Dibromcyclopropanen und Carbonylverbindungen Chemische Berichte. 115: 1990-1997. DOI: 10.1002/Cber.19821150528  0.366
1982 Seebach D, Henning R, Mukhopadhyay T. Doubly Deprotonated Methyl 3‐Mitropropanoate, an Acrylic Ester d2‐reagent Chemische Berichte. 115: 1705-1720. DOI: 10.1002/Cber.19821150505  0.321
1982 Seebach D, Prelog V. The Unambiguous Specification of the Steric Course of Asymmetric Syntheses Angewandte Chemie International Edition in English. 21: 654-660. DOI: 10.1002/Anie.198206541  0.556
1981 Knochel P, Seebach D. Nitroallylation of highly reactive organolithium compounds by 2-nitro-3-pivaloyloxy-1-propene (NPP) Tetrahedron Letters. 22: 3223-3226. DOI: 10.1016/S0040-4039(01)81868-2  0.386
1981 Seebach D, Pohmakotr M. Generation of dienone and trienone dianion derivatives : Double deprotonation as a route to lumo-filled π-systems Tetrahedron. 37: 4047-4058. DOI: 10.1016/S0040-4020(01)93280-6  0.361
1981 Seebach D, Naef R. Enantioselective Generation and Diastereoselective Reactions of Chiral Enolates Derived from α-Heterosubstituted Carboxylic Acids. Preliminary Communication† Helvetica Chimica Acta. 64: 2704-2708. DOI: 10.1002/Hlca.19810640829  0.393
1981 Seebach D, Amstutz R, Dunitz JD. Mechanistic Implications of the Tetrameric Cubic Structure of Lithium Enolates Helvetica Chimica Acta. 64: 2622-2626. DOI: 10.1002/Hlca.19810640820  0.32
1981 Olivero AG, Weidmann B, Seebach D. Enantioselective Addition of Chiral Organotitanium Derivatives to Aldehydes Helvetica Chimica Acta. 64: 2485-2488. DOI: 10.1002/Hlca.19810640755  0.37
1981 Weidmann B, Maycock CD, Seebach D. Alkyl-, Aryl-, Vinyl-, and Heterosubstituted Organozirconium Compounds. -Selective nucleophiles of low basicity. Preliminary communication Helvetica Chimica Acta. 64: 1552-1557. DOI: 10.1002/Hlca.19810640532  0.589
1981 Hungerbühler E, Seebach D, Wasmuth D. Doppelt und dreifach funktionalisierte, enantiomerenreine C4‐Synthesebausteine aus β‐Hydroxybuttersäure, Äpfelsäure und Weinsäure Helvetica Chimica Acta. 64: 1467-1487. DOI: 10.1002/Hlca.19810640523  0.354
1981 Seebach D, Goliński J. Synthesis of Open-Chain 2,3-Disubstituted 4-nitroketones by Diastereoselective Michael-addition of (E)-Enamines to (E)-Nitroolefins. A topological rule for C, C-bond forming processes between prochiral centres. Preliminary communication Helvetica Chimica Acta. 64: 1413-1423. DOI: 10.1002/Hlca.19810640518  0.361
1981 Wykypiel W, Lohmann J, Seebach D. Lithiierung in α‐Stellung zum N‐Atom von Triphenylacetamiden aus cyclischen sekundären Aminen. Umlagerung metallierter Triphenylacetamide unter 1,3‐Verschiebung der Carbamoylgruppe Helvetica Chimica Acta. 64: 1337-1346. DOI: 10.1002/Hlca.19810640510  0.326
1981 Weller T, Seebach D, Davis RE, Laird BB. 3-Hydroxy-4-nitro-cyclohexanone aus Ketonen und 4-Nitrobuttersäurechlorid. Eine ringerweiternde Fünfringanellierung Helvetica Chimica Acta. 64: 736-760. DOI: 10.1002/Hlca.19810640314  0.383
1981 Seebach D, Weller T, Protschuk G, Beck AK, Hoekstra MS. Herstellung von 1, 3-Diketonen und von Nitro-diketonen durch (1:1)-Acylierungen von Lithiumenolaten mit Acylchloriden Helvetica Chimica Acta. 64: 716-735. DOI: 10.1002/Hlca.19810640313  0.321
1981 Hungerbühler E, Seebach D. Chirale elektrophile Synthesebausteine mit vier verschiedenen funktionellen Gruppen aus Weinsäure, 2, 3‐ und 3, 4‐Epoxy‐butandiolderivate in allen vier stereoisomeren Formen Helvetica Chimica Acta. 64: 687-702. DOI: 10.1002/Hlca.19810640311  0.391
1981 Seebach D, Yoshifuji M. 2-Bis (dimethylamino)phosphinoyl-1-lithio-1, 2, 3, 4-tetrahydroisoquinoline. A highly nucleophilic d1-reagent for the preparation of 1-substituted tetrahydroisoquinolines Helvetica Chimica Acta. 64: 643-647. DOI: 10.1002/Hlca.19810640305  0.381
1981 Mali RS, Pohmakotr M, Weidmann B, Seebach D. A Short Synthesis of (R,R)-(-)-Pyrenophorin from (S)-Propylene Oxide and a 3-Pentenoic Acid d5-Reagent Liebigs Annalen Der Chemie. 1981: 2272-2284. DOI: 10.1002/Chin.198213242  0.305
1981 Seebach D, Wasmuth D. Alkylation of Amino Acids without Loss of Optical Activity:α- andβ-Alkylation of an Aspartic Acid Derivative Angewandte Chemie International Edition in English. 20: 971-971. DOI: 10.1002/Chin.198210101  0.33
1981 Colvin EW, Robertson AD, Seebach D, Beck AK. The reactions of silyl nitronates with organolithium reagents Journal of the Chemical Society, Chemical Communications. 952-953. DOI: 10.1002/Chin.198203105  0.338
1981 WEIDMANN B, MAYCOCK CD, SEEBACH D. ChemInform Abstract: ALKYL-, ARYL-, VINYL-, AND HETEROSUBSTITUTED ORGANOZIRCONIUM COMPOUNDS - SELECTIVE NUCLEOPHILES OF LOW BASICITY Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198145263  0.588
1981 WYKYPIEL W, LOHMANN J, SEEBACH D. ChemInform Abstract: LITHIATION IN α-POSITION TO THE N-ATOM OF TRIPHENYLACETAMIDES FROM CYCLIC SECONDARY AMINES. REARRANGEMENT OF METALATED TRIPHENYLACETAMIDES BY 1,3-SHIFT OF CARBAMOYL GROUPS Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198145145  0.306
1981 LOCHER R, SEEBACH D. ChemInform Abstract: MICHAEL ADDITION OF LITHIUM ACETYLIDES TO PROPENYL TRITYL KETONE Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198143078  0.349
1981 SEEBACH D, WELLER T, PROTSCHUK G, BECK AK, HOEKSTRA MS. ChemInform Abstract: PREPARATION OF 1,3-DIKETONES AND OF NITRODIKETONES BY (1:1)-ACYLATION OF LITHIUM ENOLATES WITH ACYL CHLORIDES Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198131153  0.357
1981 WELLER T, SEEBACH D, DAVIS RE, LAIRD BB. ChemInform Abstract: 3-HYDROXY-4-NITROCYCLOHEXANONES FROM KETONES AND 4-NITROBUTANOYL CHLORIDE. A RING ENLARGING FIVE-RING ANNULATION Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198131150  0.305
1981 Seebach D, Yoshifuji M. 2-Bis(Dimethylamino)Phosphinoyl-1-Lithio-1,2,3,4-Tetrahydroisoquinoline. A Highly Nucleophilic D1-Reagent For The Preparation Of 1-Substituted Tetrahydroisoquinolines Cheminform. 12. DOI: 10.1002/Chin.198130275  0.301
1981 Weidmann B, Widler L, Olivero AG, Maycock CD, Seebach D. Selectivities in the Reactions of Alkyl-, Aryl- and Heterosubstituted Organotitanium Compounds Preliminary Communication Helvetica Chimica Acta. 64: 357-361. DOI: 10.1002/Chin.198118303  0.569
1981 HUNGERBUEHLER E, NAEF R, WASMUTH D, SEEBACH D, LOOSLI H, WEHRLI A. ChemInform Abstract: SYNTHESIS OF OPTICALLY ACTIVE 2-METHYL- AND 2-ETHYL-1,6-DIOXASPIRO(4.4)NONANE AND -(4.5)DECANE PHEROMONES FROM A COMMON CHIRAL PRECURSOR Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198106333  0.301
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